Posaconazole
Title | Journal |
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Azole resistance in canine and feline isolates of Aspergillus fumigatus. | Comparative immunology, microbiology and infectious diseases 20151001 |
Studies on the antileishmanial mechanism of action of the arylimidamide DB766: azole interactions and role of CYP5122A1. | Antimicrobial agents and chemotherapy 20140801 |
Molecular identification and antifungal susceptibility of yeast isolates causing fungemia collected in a population-based study in Spain in 2010 and 2011. | Antimicrobial agents and chemotherapy 20140301 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. | Toxicological sciences : an official journal of the Society of Toxicology 20131101 |
Epidemiological cutoff values for fluconazole, itraconazole, posaconazole, and voriconazole for six Candida species as determined by the colorimetric Sensititre YeastOne method. | Journal of clinical microbiology 20130801 |
In vitro antifungal susceptibility of clinically relevant species belonging to Aspergillus section Flavi. | Antimicrobial agents and chemotherapy 20130401 |
Posaconazole exhibits in vitro and in vivo synergistic antifungal activity with caspofungin or FK506 against Candida albicans. | PloS one 20130101 |
A new solid oral tablet formulation of posaconazole: a randomized clinical trial to investigate rising single- and multiple-dose pharmacokinetics and safety in healthy volunteers. | The Journal of antimicrobial chemotherapy 20121101 |
In vitro-in vivo correlation of voriconazole resistance due to G448S mutation (cyp51A gene) in Aspergillus fumigatus. | Diagnostic microbiology and infectious disease 20121101 |
Experimental murine model of disseminated infection by Saksenaea vasiformis: successful treatment with posaconazole. | Medical mycology 20121001 |
Zygomycosis over-infection during voriconazole therapy for aspergillosis in a heart transplant patient, successfully treated with liposomal amphotericin and posaconazole. | Transplant infectious disease : an official journal of the Transplantation Society 20121001 |
Are epidemiologic cut-off values predictors of the in vivo efficacy of azoles in experimental aspergillosis? | Diagnostic microbiology and infectious disease 20121001 |
Meningitis due to Cryptococcus neoformans: treatment with posaconazole. | Current HIV research 20121001 |
Case report of hepatic mucormycosis after liver transplantation: successful treatment with liposomal amphotericin B followed by posaconazole sequential therapy. | Transplantation proceedings 20121001 |
Reversible skeletal disease and high fluoride serum levels in hematologic patients receiving voriconazole. | Blood 20120920 |
Successful treatment of cutaneous zygomycosis with extensive surgical debridement and oral posaconazole in an immunocompetent patient. | Journal of plastic, reconstructive & aesthetic surgery : JPRAS 20120901 |
Safety of posaconazole and sirolimus coadministration in allogeneic hematopoietic stem cell transplants. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120901 |
Invasive fungal breakthrough infections, fungal colonization and emergence of resistant strains in high-risk patients receiving antifungal prophylaxis with posaconazole: real-life data from a single-centre institutional retrospective observational study. | The Journal of antimicrobial chemotherapy 20120901 |
Pleurostomophora ochracea, a novel agent of human eumycetoma with yellow grains. | Journal of clinical microbiology 20120901 |
Poor absorption of high-dose posaconazole in pediatric bone marrow transplant patients. | The Annals of pharmacotherapy 20120901 |
Emergence of Aspergillus calidoustus infection in the era of posttransplantation azole prophylaxis. | Transplantation 20120827 |
Comparison of posaconazole versus weekly amphotericin B lipid complex for the prevention of invasive fungal infections in hematopoietic stem-cell transplantation. | Transplantation 20120815 |
In vitro antifungal susceptibility of filamentous fungi causing rare infections: synergy testing of amphotericin B, posaconazole and anidulafungin in pairs. | The Journal of antimicrobial chemotherapy 20120801 |
High prevalence of triazole resistance in Aspergillus fumigatus, especially mediated by TR/L98H, in a French cohort of patients with cystic fibrosis. | The Journal of antimicrobial chemotherapy 20120801 |
Characterization of an unusual ring-contraction degradant of the antifungal agent posaconazole. | Magnetic resonance in chemistry : MRC 20120801 |
Success of posaconazole therapy in a heart transplanted patient with Alternaria infectoria cutaneous infection. | Medical mycology 20120701 |
Efficacy of posaconazole in a murine model of disseminated infection caused by Apophysomyces variabilis. | The Journal of antimicrobial chemotherapy 20120701 |
Structural characterization of a novel degradant of the antifungal agent posaconazole. | Journal of pharmaceutical and biomedical analysis 20120701 |
EUCAST technical note on Aspergillus and amphotericin B, itraconazole, and posaconazole. | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20120701 |
Effects of amiodarone and posaconazole on the growth and ultrastructure of Trypanosoma cruzi. | International journal of antimicrobial agents 20120701 |
The management of febrile neutropenia in the posaconazole era: a new challenge? | Haematologica 20120701 |
Factors influencing the pharmacokinetics of prophylactic posaconazole oral suspension in patients with acute myeloid leukemia or myelodysplastic syndrome. | European journal of clinical pharmacology 20120601 |
A murine model of Cryptococcus gattii meningoencephalitis. | The Journal of antimicrobial chemotherapy 20120601 |
Posaconazole plasma concentrations and invasive mould infections in patients with haematological malignancies. | International journal of antimicrobial agents 20120601 |
Posaconazole treatment in hematology patients: a pilot study of therapeutic drug monitoring. | Therapeutic drug monitoring 20120601 |
Analogues of fenarimol are potent inhibitors of Trypanosoma cruzi and are efficacious in a murine model of Chagas disease. | Journal of medicinal chemistry 20120510 |
In vitro activity of Amphotericin B against zygomycetes isolated from deep mycoses: a comparative study between incubation in aerobic and hyperbaric atmosphere. | Medical mycology 20120501 |
Voriconazole and posaconazole improve asthma severity in allergic bronchopulmonary aspergillosis and severe asthma with fungal sensitization. | The Journal of asthma : official journal of the Association for the Care of Asthma 20120501 |
Posaconazole prophylaxis during front-line chemotherapy of acute myeloid leukemia: a single-center, real-life experience. | Haematologica 20120401 |
Impact of benzodiazepines on posaconazole serum concentrations. A population-based pharmacokinetic study on drug interaction. | Current medical research and opinion 20120401 |
In vitro antifungal susceptibility of Malassezia pachydermatis from dogs with and without skin lesions. | Veterinary microbiology 20120323 |
Successful treatment of disseminated mixed invasive fungal infection after hematopoietic stem cell transplantation for severe aplastic anemia. | Pediatric transplantation 20120301 |
Candida kefyr fungal enteritis following autologous BMT. | Bone marrow transplantation 20120301 |
Posaconazole: when and how? The clinician's view. | Mycoses 20120301 |
Comparative clinical effectiveness of prophylactic voriconazole/posaconazole to fluconazole/itraconazole in patients with acute myeloid leukemia/myelodysplastic syndrome undergoing cytotoxic chemotherapy over a 12-year period. | Haematologica 20120301 |
New species of Madurella, causative agents of black-grain mycetoma. | Journal of clinical microbiology 20120301 |
Effect of pH on in vitro susceptibility of Candida glabrata and Candida albicans to 11 antifungal agents and implications for clinical use. | Antimicrobial agents and chemotherapy 20120301 |
Rapid and sensitive determination of posaconazole in patient plasma by capillary electrophoresis with field-amplified sample stacking. | Journal of chromatography. A 20120224 |
Therapeutic drug monitoring of posaconazole in hematology adults under posaconazole prophylaxis: influence of food intake. | European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20120201 |
Disseminated sporotrichosis in a patient with hairy cell leukemia treated with amphotericin B and posaconazole. | Medical mycology 20120201 |
Long-term treatment of invasive sinus, tracheobroncheal, pulmonary and intracerebral aspergillosis in acute lymphoblastic leukaemia. | Infection 20120201 |
A randomized, placebo- and active-controlled, parallel-group, multicentre, investigator-blinded study of four treatment regimens of posaconazole in adults with toenail onychomycosis. | The British journal of dermatology 20120201 |
Posaconazole: the case for therapeutic drug monitoring. | Therapeutic drug monitoring 20120201 |
Combination therapy for mucormycosis: why, what, and how? | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20120201 |
Posaconazole serum level on day 2 predicts steady state posaconazole serum level. | Therapeutic drug monitoring 20120201 |
A multicenter, open-label study of posaconazole oral suspension in the treatment of invasive fungal infections in patients refractory to or intolerant of first-line therapy. | Future microbiology 20120201 |
In vitro activities of new triazole antifungal agents, posaconazole and voriconazole, against oral Candida isolates from patients suffering from denture stomatitis. | Mycopathologia 20120101 |
Antifungal susceptibilities of Aspergillus fumigatus clinical isolates obtained in Nagasaki, Japan. | Antimicrobial agents and chemotherapy 20120101 |
Antifungal treatment affects the laboratory diagnosis of invasive aspergillosis. | Journal of clinical pathology 20120101 |
Effect of posaconazole on the pharmacokinetics of simvastatin and midazolam in healthy volunteers. | Expert opinion on drug metabolism & toxicology 20120101 |
[53-year-old woman with life-threatening complications after use of ciprofloxacin and posaconazol]. | Deutsche medizinische Wochenschrift (1946) 20120101 |
Oral antifungal therapy for Fusarium-associated chronic rhinosinusitis. | International forum of allergy & rhinology 20120101 |
Cost-effectiveness of posaconazole versus fluconazole or itraconazole in the prevention of invasive fungal infections among high-risk neutropenic patients in Spain. | BMC infectious diseases 20120101 |
Cutaneous zygomycosis. | Clinics in dermatology 20120101 |
[Azole resistance in Aspergillus fumigatus in the Netherlands--increase due to environmental fungicides?]. | Nederlands tijdschrift voor geneeskunde 20120101 |
Paecilomyces lilacinus and alternaria infectoria cutaneous infections in a sarcoidosis patient after double-lung transplantation. | Acta clinica Belgica 20120101 |
Advances in systemic antifungal therapy. | Clinics in dermatology 20120101 |
Triazole antifungal agents in invasive fungal infections: a comparative review. | Drugs 20111224 |
Structural determination of an unknown degradation product in posaconazole drug product using CASI technology in a Fourier transform ion cyclotron resonance mass spectrometer. | Rapid communications in mass spectrometry : RCM 20111215 |
Pneumothorax and empyema complicating Scedosporium apiospermum mycetoma: not just a problem in the immunocompromised patients. | Irish journal of medical science 20111201 |
Posaconazole for the treatment of mucormycosis. | International journal of antimicrobial agents 20111201 |
In vitro activity of isavuconazole against 208 Aspergillus flavus isolates in comparison with 7 other antifungal agents: assessment according to the methodology of the European Committee on Antimicrobial Susceptibility Testing. | Diagnostic microbiology and infectious disease 20111201 |
Posaconazole for chronic refractory coccidioidal meningitis. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20111201 |
Treatment of refractory coccidioidomycosis with voriconazole or posaconazole. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20111201 |
Measurement of posaconazole, itraconazole, and hydroxyitraconazole in plasma/serum by high-performance liquid chromatography with fluorescence detection. | Therapeutic drug monitoring 20111201 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
[Antifungal therapy update: new drugs and medical uses]. | Enfermedades infecciosas y microbiologia clinica 20111201 |
Targeting calcium homeostasis as the therapy of Chagas' disease and leishmaniasis - a review. | Tropical biomedicine 20111201 |
[In vitro synergisms among hydrazones, ajoeno and posaconazole against Cryptococcus spp]. | Investigacion clinica 20111201 |
A dried blood spots technique based LC-MS/MS method for the analysis of posaconazole in human whole blood samples. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111115 |
Posaconazole versus fluconazole or itraconazole for prevention of invasive fungal infections in patients undergoing intensive cytotoxic therapy for acute myeloid leukemia or myelodysplasia: a cost effectiveness analysis. | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20111101 |
A prospective survey of Aspergillus spp. in respiratory tract samples: prevalence, clinical impact and antifungal susceptibility. | European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20111101 |
Microdilution in vitro antifungal susceptibility of Exophiala dermatitidis, a systemic opportunist. | Medical mycology 20111101 |
Optimising absorption of posaconazole. | Mycoses 20111101 |
Triazole and echinocandin MIC distributions with epidemiological cutoff values for differentiation of wild-type strains from non-wild-type strains of six uncommon species of Candida. | Journal of clinical microbiology 20111101 |
Wild-type MIC distributions and epidemiologic cutoff values for fluconazole, posaconazole, and voriconazole when testing Cryptococcus neoformans as determined by the CLSI broth microdilution method. | Diagnostic microbiology and infectious disease 20111101 |
EUCAST technical note on posaconazole. | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20111101 |
Effect of pH and comedication on gastrointestinal absorption of posaconazole: monitoring of intraluminal and plasma drug concentrations. | Clinical pharmacokinetics 20111101 |
A common fungus, an unusual (and deadly) infection. | The American journal of medicine 20111101 |
T. asahii pulmonary infection as a complication of TNF-inhibitor and steroids: posaconazole pharmacotherapy and risk analysis. | Journal of the Mississippi State Medical Association 20111101 |
[Exophytic and ulcerative lesions on the lower limb in a Moroccan patient]. | Medicina clinica 20111015 |
Risk factors for invasive aspergillosis in acute myeloid leukemia patients prophylactically treated with posaconazole. | Medical mycology 20111001 |
In vitro activity of a novel broad-spectrum antifungal, E1210, tested against Candida spp. as determined by CLSI broth microdilution method. | Diagnostic microbiology and infectious disease 20111001 |
Update in treatment of Chagas disease. | Current opinion in infectious diseases 20111001 |
Breakthrough fungemia due to Candida glabrata during posaconazole prophylaxis in hematology patients treated with anidulafungin - report of 5 cases. | Journal of chemotherapy (Florence, Italy) 20111001 |
In vitro susceptibility of filamentous fungi to itraconazole, voriconazole and posaconazole by Clinical and Laboratory Standards Institute reference method and E-test. | Mycoses 20110901 |
Antifungal activity of posaconazole and granulocyte colony-stimulating factor in the treatment of disseminated zygomycosis (mucormycosis) in a neutropaenic murine model. | Mycoses 20110901 |
Posaconazole: a new antifungal weapon. | Reviews on recent clinical trials 20110901 |
Peripheral neuropathy in patients on long-term triazole antifungal therapy. | The Journal of antimicrobial chemotherapy 20110901 |
A twice daily posaconazole dosing algorithm for children with chronic granulomatous disease. | The Pediatric infectious disease journal 20110901 |
Rhino-orbital-cerebral mucormycosis (ROCM): a comprehensive case review. | Aviation, space, and environmental medicine 20110901 |
74-year-old man from the pacific northwest with fever and a lung mass. | Chest 20110901 |
Disseminated nocardiosis masking an atypical zygomycosis presentation in a kidney transplant recipient. | Transplant infectious disease : an official journal of the Transplantation Society 20110801 |
Endophthalmitis as primary clinical manifestation of fatal fusariosis in an allogeneic stem cell recipient. | Transplant infectious disease : an official journal of the Transplantation Society 20110801 |
Fatal disseminated infection due to Scedosporium prolificans in a patient with acute myeloid leukemia and posaconazole prophylaxis. | Leukemia & lymphoma 20110801 |
Posaconazole plasma concentrations in critically ill patients. | Therapeutic drug monitoring 20110801 |
Madurella mycetomatis mycetoma treated successfully with oral posaconazole. | Journal of chemotherapy (Florence, Italy) 20110801 |
Posaconazole prophylaxis during induction therapy of patients with acute lymphoblastic leukaemia. | Mycoses 20110701 |
Cavitary lung lesions in a renal transplant recipient. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20110701 |
Synthesis and in vitro antimicrobial activities of new (cyano-NNO-azoxy)pyrazole derivatives. | Bioorganic & medicinal chemistry letters 20110601 |
Selection of resistant fungi in liver transplant recipients during use of newer antifungal agents -- a report of two cases. | Annals of the Academy of Medicine, Singapore 20110601 |
European guidelines for antifungal management in leukemia and hematopoietic stem cell transplant recipients: summary of the ECIL 3--2009 update. | Bone marrow transplantation 20110501 |
Clinical efficacy and safety of primary antifungal prophylaxis with posaconazole vs itraconazole in allogeneic blood and marrow transplantation. | Bone marrow transplantation 20110501 |
Pharmacokinetics and pharmacodynamics of posaconazole for invasive pulmonary aspergillosis: clinical implications for antifungal therapy. | The Journal of infectious diseases 20110501 |
Cerebral mucormycosis in a diabetic man. | Connecticut medicine 20110501 |
Efficacy, safety, and breakthrough infections associated with standard long-term posaconazole antifungal prophylaxis in allogeneic stem cell transplantation recipients. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110401 |
Aspergillus endocarditis 2003-2009. | Medical mycology 20110401 |
Retrospective survey on the off-label use of posaconazole in pediatric hematology patients. | European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20110401 |
Multilaboratory testing of two-drug combinations of antifungals against Candida albicans, Candida glabrata, and Candida parapsilosis. | Antimicrobial agents and chemotherapy 20110401 |
Delayed recalcitrant fungal endophthalmitis secondary to Curvularia. | Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20110401 |
Therapeutic efficacy of posaconazole against Candida glabrata in a murine model of vaginitis. | Mycoses 20110301 |
Combined therapy against murine-disseminated infection by Fusarium verticillioides. | Mycopathologia 20110301 |
Posaconazole susceptibility of clinical yeast isolates determined by an agar diffusion and microdilution method. | International journal of antimicrobial agents 20110301 |
A post-marketing evaluation of posaconazole plasma concentrations in neutropenic patients with haematological malignancy receiving posaconazole prophylaxis. | International journal of antimicrobial agents 20110301 |
Lack of evidence for exposure-response relationship in the use of posaconazole as prophylaxis against invasive fungal infections. | Clinical pharmacology and therapeutics 20110301 |
Posaconazole: a pharmacoeconomic review of its use in the prophylaxis of invasive fungal disease in immunocompromised hosts. | PharmacoEconomics 20110301 |
Low prevalence of resistance to azoles in Aspergillus fumigatus in a French cohort of patients treated for haematological malignancies. | The Journal of antimicrobial chemotherapy 20110201 |
Therapeutic drug monitoring of voriconazole and posaconazole. | Pharmacotherapy 20110201 |
Lack of pharmacokinetic drug interaction between oral posaconazole and caspofungin or micafungin. | Journal of clinical pharmacology 20110101 |
Two new species of Mucor from clinical samples. | Medical mycology 20110101 |
Posaconazole cerebrospinal concentrations in an HIV-infected patient with brain mucormycosis. | The Journal of antimicrobial chemotherapy 20110101 |
Posaconazole prophylaxis in patients with acute myelogenous leukaemia--results from an observational study. | Mycoses 20110101 |
Clinical experience with posaconazole prophylaxis--a retrospective analysis in a haematological unit. | Mycoses 20110101 |
Posaconazole: clinical pharmacokinetics and drug interactions. | Mycoses 20110101 |
Caspofungin plus posaconazole as salvage therapy of invasive fungal infections in immunocompromised patients. | Mycoses 20110101 |
Posaconazole as part of the antifungal armamentarium in the intensive care unit--case reports from a surgical ICU. | Mycoses 20110101 |
Cost effectiveness of posaconazole in the prophylaxis of invasive fungal infections in acute leukaemia patients for the French healthcare system. | Journal of medical economics 20110101 |
Successful treatment of chronic mucocutaneous candidiasis caused by azole-resistant Candida albicans with posaconazole. | Clinical & developmental immunology 20110101 |
Pharmacology and metabolism of voriconazole and Posaconazole in the treatment of invasive aspergillosis: review of the literature. | European journal of medical research 20110101 |
Prophylaxis and treatment of invasive aspergillosis with voriconazole, posaconazole and caspofungin: review of the literature. | European journal of medical research 20110101 |
Antimalarial activity of potential inhibitors of Plasmodium falciparum lactate dehydrogenase enzyme selected by docking studies. | PloS one 20110101 |
Targeting Trypanosoma cruzi sterol 14α-demethylase (CYP51). | Advances in parasitology 20110101 |
Long-term treatment of refractory invasive fungal infection with posaconazole: additive value of therapeutic drug monitoring. | Acta clinica Belgica 20110101 |
[Cost effectiveness of posaconazole versus fluconazole/itraconazole in the prophylactic treatment of invasive fungal infections in Mexico]. | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20110101 |
Posaconazole for chronic pulmonary aspergillosis: the next strategy against the threat of azole-resistant Aspergillus infection. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20101215 |
Efficacy and safety of posaconazole for chronic pulmonary aspergillosis. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20101215 |
Use of posaconazole in the treatment of infective rhinocerebral mucormycosis. | The Journal of laryngology and otology 20101201 |
Impact of glucuronide interferences on therapeutic drug monitoring of posaconazole by tandem mass spectrometry. | Clinical chemistry and laboratory medicine 20101201 |
In vitro antifungal susceptibilities and amplified fragment length polymorphism genotyping of a worldwide collection of 350 clinical, veterinary, and environmental Cryptococcus gattii isolates. | Antimicrobial agents and chemotherapy 20101201 |
Multiplex ultra-performance liquid chromatography-tandem mass spectrometry method for simultaneous quantification in human plasma of fluconazole, itraconazole, hydroxyitraconazole, posaconazole, voriconazole, voriconazole-N-oxide, anidulafungin, and caspofungin. | Antimicrobial agents and chemotherapy 20101201 |
Ultra-performance liquid chromatography mass spectrometry and sensitive bioassay methods for quantification of posaconazole plasma concentrations after oral dosing. | Antimicrobial agents and chemotherapy 20101201 |
Molecular phylogeny and proposal of two new species of the emerging pathogenic fungus Saksenaea. | Journal of clinical microbiology 20101201 |
Sixty-year-old man with slowly expanding nodular plaque on the thigh. | Journal of the American Academy of Dermatology 20101201 |
Managing invasive fungal disease in immunocompromised patients. | Future microbiology 20101201 |
Successful treatment of cutaneous zygomycosis with intravenous amphotericin B followed by oral posaconazole in a multivisceral transplant recipient. | Transplantation 20101127 |
AfMkk2 is required for cell wall integrity signaling, adhesion, and full virulence of the human pathogen Aspergillus fumigatus. | International journal of medical microbiology : IJMM 20101101 |
Isavuconazole: a comprehensive review of spectrum of activity of a new triazole. | Mycopathologia 20101101 |
Complementation of a Saccharomyces cerevisiae ERG11/CYP51 (sterol 14α-demethylase) doxycycline-regulated mutant and screening of the azole sensitivity of Aspergillus fumigatus isoenzymes CYP51A and CYP51B. | Antimicrobial agents and chemotherapy 20101101 |
In vitro and in vivo antifungal susceptibilities of the Mucoralean fungus Cunninghamella. | Antimicrobial agents and chemotherapy 20101101 |
Environmental study of azole-resistant Aspergillus fumigatus and other aspergilli in Austria, Denmark, and Spain. | Antimicrobial agents and chemotherapy 20101101 |
Antifungal therapy in a murine model of disseminated infection by Cryptococcus gattii. | Antimicrobial agents and chemotherapy 20101001 |
Expression, purification, and characterization of Aspergillus fumigatus sterol 14-alpha demethylase (CYP51) isoenzymes A and B. | Antimicrobial agents and chemotherapy 20101001 |
In vitro and in vivo activities of posaconazole against zygomycetes with various degrees of susceptibility. | The Journal of antimicrobial chemotherapy 20101001 |
Effect of posaconazole on the pharmacokinetics of fosamprenavir and vice versa in healthy volunteers. | The Journal of antimicrobial chemotherapy 20101001 |
Azole antifungal resistance in Aspergillus fumigatus: 2008 and 2009. | The Journal of antimicrobial chemotherapy 20101001 |
Comparative survival and cost of antifungal therapy: posaconazole versus standard antifungals in the treatment of refractory invasive aspergillosis. | Current medical research and opinion 20101001 |
Clinical pharmacodynamics and pharmacokinetics of the antifungal extended-spectrum triazole posaconazole: an overview. | British journal of clinical pharmacology 20101001 |
In vitro susceptibility testing of Aspergillus spp. against voriconazole, itraconazole, posaconazole, amphotericin B and caspofungin. | Chinese medical journal 20101001 |
A noninvasive renal fungus ball caused by Rhizopus--a previously unreported manifestation of zygomycosis. | Medical mycology 20100901 |
Economic evaluation of posaconazole versus fluconazole prophylaxis in patients with graft-versus-host disease (GVHD) in the Netherlands. | Annals of hematology 20100901 |
Steady-state intrapulmonary pharmacokinetics and pharmacodynamics of posaconazole in lung transplant recipients. | Antimicrobial agents and chemotherapy 20100901 |
Therapeutic drug monitoring of posaconazole in hematology patients: experience with a new high-performance liquid chromatography-based method. | Antimicrobial agents and chemotherapy 20100901 |
Experimental murine scedosporiosis: histopathology and azole treatment. | Antimicrobial agents and chemotherapy 20100901 |
In vitro antifungal activities of isavuconazole and comparators against rare yeast pathogens. | Antimicrobial agents and chemotherapy 20100901 |
Wild-type MIC distributions and epidemiological cutoff values for the triazoles and six Aspergillus spp. for the CLSI broth microdilution method (M38-A2 document). | Journal of clinical microbiology 20100901 |
Antifungal activity of posaconazole against Candida spp. and non-Candida clinical yeasts isolates. | Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20100901 |
Ulcerated plaque under a ruby ring in an immunosuppressed patient. | Dermatology online journal 20100815 |
Structural insights into inhibition of sterol 14alpha-demethylase in the human pathogen Trypanosoma cruzi. | The Journal of biological chemistry 20100813 |
Cunninghamella bertholletiae exhibits increased resistance to human neutrophils with or without antifungal agents as compared to Rhizopus spp. | Medical mycology 20100801 |
Posaconazole salvage treatment in paediatric patients: a multicentre survey. | European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20100801 |
Development, validation, and routine application of a high-performance liquid chromatography method coupled with a single mass detector for quantification of itraconazole, voriconazole, and posaconazole in human plasma. | Antimicrobial agents and chemotherapy 20100801 |
Clinical effectiveness of posaconazole prophylaxis in patients with acute myelogenous leukaemia (AML): a 6 year experience of the Cologne AML cohort. | The Journal of antimicrobial chemotherapy 20100701 |
Antifungal susceptibility profile of human-pathogenic species of Lichtheimia. | Antimicrobial agents and chemotherapy 20100701 |
A comparative study of posaconazole and benznidazole in the prevention of heart damage and promotion of trypanocidal immune response in a murine model of Chagas disease. | International journal of antimicrobial agents 20100701 |
Intracellular concentrations of posaconazole in different compartments of peripheral blood. | Antimicrobial agents and chemotherapy 20100701 |
Antifungal therapies in murine disseminated phaeohyphomycoses caused by Exophiala species. | The Journal of antimicrobial chemotherapy 20100701 |
Exposure-response of posaconazole used for prophylaxis against invasive fungal infections: evaluating the need to adjust doses based on drug concentrations in plasma. | Clinical pharmacology and therapeutics 20100701 |
Chagas disease: pushing through the pipeline. | Nature 20100624 |
Conazoles. | Molecules (Basel, Switzerland) 20100609 |
Azole resistance in allergic bronchopulmonary aspergillosis and Aspergillus bronchitis. | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20100601 |
Emerging therapeutic options in fulminant invasive rhinocerebral mucormycosis. | Auris, nasus, larynx 20100601 |
Breakthrough zygomycosis on posaconazole prophylaxis after allogeneic stem cell transplantation. | Transplant infectious disease : an official journal of the Transplantation Society 20100601 |
Disseminated Rhizopus microsporus infection cured by salvage allogeneic hematopoietic stem cell transplantation, antifungal combination therapy, and surgical resection. | Transplant infectious disease : an official journal of the Transplantation Society 20100601 |
Potential synergistic activity of antimycotic substances in combination with human platelets against Aspergillus fumigatus. | The Journal of antimicrobial chemotherapy 20100601 |
Pharmacokinetic/pharmacodynamic profile of posaconazole. | Clinical pharmacokinetics 20100601 |
Rhizopus oryzae skin infection treated with posaconazole in a boy with chronic granulomatous disease. | The Pediatric infectious disease journal 20100601 |
Mucormycosis may mimic disease relapse in Wegener's granulomatosis. | The Journal of rheumatology 20100601 |
[Economic evaluation of posaconazole in prophylaxis of invasive fungal infections in Italian neutropenic patients with acute myeloid leukaemia or myelodysplastic syndrome]. | Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20100601 |
Second generation analogues of the cancer drug clinical candidate tipifarnib for anti-Chagas disease drug discovery. | Journal of medicinal chemistry 20100527 |
Antifungal activity of amphotericin B, caspofungin and posaconazole on Candida albicans biofilms in intermediate and mature development phases. | Mycoses 20100501 |
Economic evaluation of posaconazole vs fluconazole in the prevention of invasive fungal infections in patients with GVHD following haematopoietic SCT. | Bone marrow transplantation 20100501 |
Correlation between in vitro activity of posaconazole and in vivo efficacy against Rhizopus oryzae infection in mice. | Antimicrobial agents and chemotherapy 20100501 |
Cutaneous model of invasive aspergillosis. | Antimicrobial agents and chemotherapy 20100501 |
Use of a high-resolution melt assay to characterize codon 54 of the cyp51A gene of Aspergillus fumigatus on a Rotor-Gene 6000 instrument. | Antimicrobial agents and chemotherapy 20100501 |
Skin concentrations and pharmacokinetics of posaconazole after oral administration. | Antimicrobial agents and chemotherapy 20100501 |
Severe life threatening neurotoxicity in a child with acute lymphoblastic leukemia receiving posaconazole and vincristine. | Pediatric blood & cancer 20100501 |
Pharmacoeconomic evaluation of voriconazole versus posaconazole for antifungal prophylaxis in acute myeloid leukaemia. | The Journal of antimicrobial chemotherapy 20100501 |
Traditional and emerging antifungal therapies. | Proceedings of the American Thoracic Society 20100501 |
[Prophylaxis use of posaconazole (P) in an hemato-oncology unit: a retrospective study]. | Pathologie-biologie 20100401 |
Unusual presentation of chromoblastomycosis due to Cladophialophora carrionii in a renal and pancreas transplant recipient patient successfully treated with posaconazole and surgical excision. | Transplant infectious disease : an official journal of the Transplantation Society 20100401 |
In vitro activities of eight antifungal drugs against 55 clinical isolates of Fonsecaea spp. | Antimicrobial agents and chemotherapy 20100401 |
In vitro interaction of posaconazole with calcineurin inhibitors and sirolimus against zygomycetes. | The Journal of antimicrobial chemotherapy 20100401 |
Successful treatment with posaconazole of a patient with chronic Chagas disease and systemic lupus erythematosus. | The American journal of tropical medicine and hygiene 20100401 |
Structural characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei bound to the antifungal drugs posaconazole and fluconazole. | PLoS neglected tropical diseases 20100401 |
Presumed Scopulariopsis brevicaulis chorioretinitis in a stem cell transplant recipient. | Clinical & experimental ophthalmology 20100401 |
Rifampin and posaconazole coadministration leads to decreased serum posaconazole concentrations. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100315 |
Onychomycosis. | Clinics in dermatology 20100304 |
Successful treatment of pulmonary zygomycosis in two transplant recipients with liposomal amphotericin B and partial surgical resection followed by posaconazole. | Mycoses 20100301 |
Splenic hyalohyphomycosis, molecularly and immunologically consistent with invasive aspergillosis, in a patient with acute lymphoblastic leukemia. | American journal of hematology 20100301 |
Müeller-Hinton methylene blue media as an alternative to RPMI 1640 for determining the susceptibility of Cryptococcus neoformans and Cryptococcus gattii to posaconazole with Etest. | Mycoses 20100301 |
Efficacy of posaconazole as treatment and prophylaxis against Fusarium solani. | Antimicrobial agents and chemotherapy 20100301 |
Current controversies in treating invasive zygomycosis. | Journal of pediatric hematology/oncology 20100301 |
Successful triple combination therapy of disseminated absidia corymbifera infection in an adolescent with osteosarcoma. | Journal of pediatric hematology/oncology 20100301 |
Report of a successful treatment of pulmonary Cunninghamella bertholletiae infection with liposomal amphotericin and posaconazole in a child with GvHD and review of the literature. | Journal of pediatric hematology/oncology 20100301 |
Sinonasal mucormycosis: case report. | European annals of otorhinolaryngology, head and neck diseases 20100301 |
Drug costs and utilization after implementation of a posaconazole prophylaxis protocol in adults with acute myelogenous leukemia. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100215 |
[Painful peripheral neuropathy associated with voriconazole during the treatment of chronic cavitary pulmonary aspergillosis]. | La Revue de medecine interne 20100201 |
Efficacy of posaconazole against three clinical Aspergillus fumigatus isolates with mutations in the cyp51A gene. | Antimicrobial agents and chemotherapy 20100201 |
In vitro activity of antifungal combinations against Candida albicans biofilms. | The Journal of antimicrobial chemotherapy 20100201 |
Population pharmacokinetics of posaconazole in neutropenic patients receiving chemotherapy for acute myelogenous leukemia or myelodysplastic syndrome. | Current medical research and opinion 20100201 |
Evaluation of antifungal therapy in a neutropenic murine model of Neoscytalidium dimidiatum infection. | International journal of antimicrobial agents 20100201 |
Murine model of a disseminated infection by the novel fungus Fonsecaea monophora and successful treatment with posaconazole. | Antimicrobial agents and chemotherapy 20100201 |
Malignant thymoma with immunodeficiency (Good syndrome) associated with mucormycosis. | American journal of clinical oncology 20100201 |
Efficacy of combined surgery and antifungal therapies for the management of invasive zygomycoses in patients with haematological malignancies. | Mycoses 20100101 |
Iatrogenic eyelid granulomata. | American journal of therapeutics 20100101 |
Efficacy of posaconazole in a murine disseminated infection by Candida tropicalis. | Antimicrobial agents and chemotherapy 20100101 |
Factors influencing pharmacokinetics of prophylactic posaconazole in patients undergoing allogeneic stem cell transplantation. | Antimicrobial agents and chemotherapy 20100101 |
Pharmacokinetics of a single dose of the antifungal posaconazole as oral suspension in subjects with hepatic impairment. | Current medical research and opinion 20100101 |
Primary antifungal prophylaxis in acute myeloblastic leukemia and myelodysplastic syndrome--still an open question? | Leukemia & lymphoma 20100101 |
Cost-effectiveness of posaconazole compared with standard azole therapy for prevention of invasive fungal infections in patients at high risk in Switzerland. | Oncology 20100101 |
Intermittent posaconazole regimen to treat superficial Scytalidium dimidiatum infection. | European journal of dermatology : EJD 20100101 |
Posaconazole. | Journal of postgraduate medicine 20100101 |
Development, clinical utility, and place in therapy of posaconazole for prevention and treatment of invasive fungal infections. | Drug design, development and therapy 20100101 |
Simultaneous determination of five systemic azoles in plasma by high-performance liquid chromatography with ultraviolet detection. | Journal of pharmaceutical and biomedical analysis 20091205 |
Therapeutic drug monitoring of posaconazole: a monocentric study with 54 adults. | Antimicrobial agents and chemotherapy 20091201 |
Impact of antifungal prophylaxis on colonization and azole susceptibility of Candida species. | Antimicrobial agents and chemotherapy 20091201 |
Correlation of in vitro activity, serum levels, and in vivo efficacy of posaconazole against Rhizopus microsporus in a murine disseminated infection. | Antimicrobial agents and chemotherapy 20091201 |
Activity of MGCD290, a Hos2 histone deacetylase inhibitor, in combination with azole antifungals against opportunistic fungal pathogens. | Journal of clinical microbiology 20091201 |
Phospholipidosis in neurons caused by posaconazole, without evidence for functional neurologic effects. | Toxicologic pathology 20091201 |
Isoquinoline-based analogs of the cancer drug clinical candidate tipifarnib as anti-Trypanosoma cruzi agents. | Bioorganic & medicinal chemistry letters 20091201 |
Successful treatment of ascending aortic graft and valve endocarditis after debulking splenectomy for invasive aspergillosis and mucor. | The American surgeon 20091201 |
Use of posaconazole in the treatment of invasive fungal infections. | Expert review of hematology 20091201 |
Cutaneous zygomycosis caused by Saksenaea vasiformis following water-related wound in a 24-year-old immunocompetent woman. | Mycoses 20091101 |
Comparison of assessment of oxygen consumption, Etest, and CLSI M38-A2 broth microdilution methods for evaluation of the susceptibility of Aspergillus fumigatus to posaconazole. | Antimicrobial agents and chemotherapy 20091101 |
Effect of varying amounts of a liquid nutritional supplement on the pharmacokinetics of posaconazole in healthy volunteers. | Antimicrobial agents and chemotherapy 20091101 |
Posaconazole attenuates leukotriene B4 release and uptake of calcium by chemoattractant-activated human neutrophils: a potential strategy to control neutrophil-mediated inflammation. | The Journal of antimicrobial chemotherapy 20091101 |
[Non-fatal disseminated mucormycosis in a solid organ transplant]. | Revue des maladies respiratoires 20091101 |
Successful nonoperative management of gastrointestinal mucormycosis: novel therapy for invasive disease. | Surgical infections 20091001 |
Atypical Aspergillus flavus isolates associated with chronic azole therapy. | Journal of clinical microbiology 20091001 |
Disseminated zygomycosis with involvement of the central nervous system. | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20091001 |
In vitro activity of antifungals against Zygomycetes. | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20091001 |
Current experience in treating invasive zygomycosis with posaconazole. | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20091001 |
Hyperbaric oxygen therapy and other adjunctive treatments for zygomycosis. | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20091001 |
Evaluating the resistance to posaconazole by E-test and CLSI broth microdilution methodologies of Candida spp. and pathogenic moulds. | European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20090901 |
ZYGOMYCOSIS: current approaches to management of patients with haematological malignancies. | British journal of haematology 20090901 |
A high-throughput LC-MS/MS method for the quantitation of posaconazole in human plasma: Implementing fused core silica liquid chromatography. | Journal of pharmaceutical and biomedical analysis 20090815 |
Determination of the antifungal agent posaconazole in human serum by HPLC with parallel column-switching technique. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090815 |
Limited penetration of posaconazole into cerebrospinal fluid in an allogeneic stem cell recipient with invasive pulmonary aspergillosis. | Bone marrow transplantation 20090801 |
In vitro interactions between antifungals and immunosuppressive drugs against zygomycetes. | Antimicrobial agents and chemotherapy 20090801 |
Efficacy of triazoles in a murine disseminated infection by Candida krusei. | Antimicrobial agents and chemotherapy 20090801 |
Fatal rhizopus pneumonia in allogeneic stem cell transplant patients despite posaconazole prophylaxis: two cases and review of the literature. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20090801 |
What should be the first-choice strategy to maximize posaconazole exposure in daily clinical practice? | Antimicrobial agents and chemotherapy 20090801 |
Effects of oral posaconazole on the pharmacokinetics of atazanavir alone and with ritonavir or with efavirenz in healthy adult volunteers. | Journal of acquired immune deficiency syndromes (1999) 20090801 |
Posaconazole-induced topiramate toxicity. | Annals of internal medicine 20090721 |
Treatment of intestinal and hepatic mucormycosis in an immunocompromized child. | Pediatric blood & cancer 20090701 |
Simultaneous determination of voriconazole and posaconazole concentrations in human plasma by high-performance liquid chromatography. | Antimicrobial agents and chemotherapy 20090701 |
Pharmacokinetics of posaconazole administered orally or by nasogastric tube in healthy volunteers. | Antimicrobial agents and chemotherapy 20090701 |
Structurally simple inhibitors of lanosterol 14alpha-demethylase are efficacious in a rodent model of acute Chagas disease. | Journal of medicinal chemistry 20090625 |
Recent advances in the management of mucormycosis: from bench to bedside. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090615 |
Long-term posaconazole treatment and follow-up of rhino-orbital-cerebral mucormycosis in a diabetic girl. | Pediatric diabetes 20090601 |
Safe management of tacrolimus together with posaconazole in lung transplant patients with cystic fibrosis. | Therapeutic drug monitoring 20090601 |
Dynamics of in vitro acquisition of resistance by Candida parapsilosis to different azoles. | FEMS yeast research 20090601 |
Cutaneous infection caused by Macrophomina phaseolina in a child with acute myeloid leukemia. | Journal of clinical microbiology 20090601 |
Tolerability and safety profile of posaconazole: evaluation of 18 controlled studies in healthy volunteers. | Journal of clinical pharmacy and therapeutics 20090601 |
Successful therapy with ABLC, surgery and posaconazole for Rhizopus microsporus var. rhizopodiformis liver eumycetoma in a child with acute leukaemia. | Mycoses 20090501 |
Triazole-resistant candidaemia following posaconazole exposure. | International journal of antimicrobial agents 20090501 |
Posaconazole therapeutic drug monitoring: a reference laboratory experience. | Antimicrobial agents and chemotherapy 20090501 |
The changing face of febrile neutropenia-from monotherapy to moulds to mucositis. Prevention of mould infections. | The Journal of antimicrobial chemotherapy 20090501 |
Diagnosis and treatment of aspergillosis in children. | Expert review of anti-infective therapy 20090501 |
Rhinocerebral mucormycosis. | British journal of hospital medicine (London, England : 2005) 20090501 |
Trichosporon mucoides fungemia in a liver transplant recipient: case report and review. | Transplant infectious disease : an official journal of the Transplantation Society 20090401 |
Mucor circinelloides as a cause of invasive maxillofacial zygomycosis: an emerging dimorphic pathogen with reduced susceptibility to posaconazole. | Journal of clinical microbiology 20090401 |
Activity of posaconazole and other antifungal agents against Mucorales strains identified by sequencing of internal transcribed spacers. | Antimicrobial agents and chemotherapy 20090401 |
Interactions between triazoles and amphotericin B in treatment of disseminated murine infection by Fusarium oxysporum. | Antimicrobial agents and chemotherapy 20090401 |
A comparison of the fungicidal activity of amphotericin B and posaconazole against Zygomycetes in vitro. | Diagnostic microbiology and infectious disease 20090401 |
Posaconazole for bone-invading rhinomaxillary mucormycosis. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20090401 |
Posaconazole-increased vincristine neurotoxicity in a child: a case report. | Journal of pediatric hematology/oncology 20090401 |
Rational modification of a candidate cancer drug for use against Chagas disease. | Journal of medicinal chemistry 20090326 |
Omeprazole significantly reduces posaconazole serum trough level. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090315 |
Susceptibility testing of Cryptococcus diffluens against amphotericin B, flucytosine, fluconazole, itraconazole, voriconazole and posaconazole. | Medical mycology 20090301 |
Pharmacokinetics and absorption of posaconazole oral suspension under various gastric conditions in healthy volunteers. | Antimicrobial agents and chemotherapy 20090301 |
Multiple-azole-resistant Aspergillus fumigatus osteomyelitis in a patient with chronic granulomatous disease successfully treated with long-term oral posaconazole and surgery. | Medical mycology 20090301 |
Effects of oral posaconazole on the pharmacokinetics of sirolimus. | Current medical research and opinion 20090301 |
Posaconazole's impact on prophylaxis and treatment of invasive fungal infections: an update. | Expert review of anti-infective therapy 20090301 |
Posaconazole mono- or combination therapy for treatment of murine zygomycosis. | Antimicrobial agents and chemotherapy 20090201 |
Intrapulmonary pharmacokinetics and pharmacodynamics of posaconazole at steady state in healthy subjects. | Antimicrobial agents and chemotherapy 20090201 |
Posaconazole efficacy in a murine disseminated infection caused by Paecilomyces lilacinus. | The Journal of antimicrobial chemotherapy 20090201 |
Antifungal susceptibility testing of Exophiala spp.: a head-to-head comparison of amphotericin B, itraconazole, posaconazole and voriconazole. | Medical mycology 20090201 |
Posaconazole: a new oral antifungal agent with an expanded spectrum of activity. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090201 |
Effects of oral posaconazole on the pharmacokinetic properties of oral and intravenous midazolam: a phase I, randomized, open-label, crossover study in healthy volunteers. | Clinical therapeutics 20090201 |
[Amphotericin and posaconazole for gastrointestinal mucormycosis]. | Revista espanola de anestesiologia y reanimacion 20090201 |
Rhino-cerebral zygomycosis resistant to antimycotic treatment: a case report. | Mycoses 20090101 |
Successful treatment of relapsing disseminated coccidioidomycosis with cutaneous involvement with posaconazole. | Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20090101 |
Antifungal susceptibilities among different serotypes of Cryptococcus gattii and Cryptococcus neoformans. | Antimicrobial agents and chemotherapy 20090101 |
Absence of CD4+ T lymphocytes, CD8+ T lymphocytes, or B lymphocytes has different effects on the efficacy of posaconazole and benznidazole in treatment of experimental acute Trypanosoma cruzi infection. | Antimicrobial agents and chemotherapy 20090101 |
International interlaboratory proficiency testing program for measurement of azole antifungal plasma concentrations. | Antimicrobial agents and chemotherapy 20090101 |
Voriconazole and posaconazole resistant Candida pelliculosa fungemia after cardiac surgery. | The Pediatric infectious disease journal 20090101 |
An increasing trend of cutaneous zygomycosis caused by Mycocladus corymbifer (formerly Absidia corymbifera): report of two cases and review of primary cutaneous Mycocladus infections. | Medical mycology 20090101 |
A routine method for the quantification of the novel antimycotic drug posaconazole in plasma using liquid chromatography-tandem mass spectrometry. | Clinical chemistry and laboratory medicine 20090101 |
Successful treatment of Cryptococcal meningitis with a combination of liposomal amphotericin B, flucytosine and posaconazole: two case reports. | In vivo (Athens, Greece) 20090101 |
Management of metabolic cytochrome P450 3A4 drug-drug interaction between everolimus and azole antifungals in a renal transplant patient. | Clinical drug investigation 20090101 |
Primary cutaneous mucormycosis in a lung transplant recipient: case report and concise review of the literature. | Transplant infectious disease : an official journal of the Transplantation Society 20081201 |
Breakthrough invasive fungal infection in an immunocompromised host while on posaconazole prophylaxis: an omission in patient counseling and follow-up. | Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20081201 |
Economic evaluation of posaconazole vs. standard azole prophylaxis in high risk neutropenic patients in the Netherlands. | European journal of haematology 20081201 |
Posaconazole concentrations in the central nervous system. | The Journal of antimicrobial chemotherapy 20081201 |
Posaconazole as salvage treatment of invasive fungal infections in patients with underlying renal impairment. | The Journal of antimicrobial chemotherapy 20081201 |
Comparative cost-effectiveness of posaconazole versus fluconazole or itraconazole prophylaxis in patients with prolonged neutropenia. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20081201 |
[Trends in development of new antifungal agents in Japan]. | Nihon rinsho. Japanese journal of clinical medicine 20081201 |
Clinical experience with posaconazole in patients with invasive mucormycosis: a case series. | Puerto Rico health sciences journal 20081201 |
[Invasive pulmonary mucormycosis with invasion of the thoracic spine in a patient with myelodysplastic syndrome]. | Revue medicale de Liege 20081201 |
Disseminated Saksenaea vasiformis in an immunocompetent host. | The Medical journal of Australia 20081103 |
Posaconazole as first line treatment for disseminated zygomycosis. | Mycoses 20081101 |
[Posaconazole: another triazole antifungal of the new generation?]. | Deutsche medizinische Wochenschrift (1946) 20081101 |
In vitro susceptibility of Pythium insidiosum and a Lagenidium sp to itraconazole, posaconazole, voriconazole, terbinafine, caspofungin, and mefenoxam. | American journal of veterinary research 20081101 |
Emergence of azole resistance in Aspergillus fumigatus and spread of a single resistance mechanism. | PLoS medicine 20081101 |
Fatal Aspergillus fumigatus and Candida glabrata infections with posaconazole prophylaxis after stem cell transplantation. | International journal of antimicrobial agents 20081001 |
Breakthrough Rhizopus infection on posaconazole prophylaxis following allogeneic stem cell transplantation. | Bone marrow transplantation 20081001 |
Infection of the subcutis of the nose in a cat caused by Mucor species: successful treatment using posaconazole. | Journal of feline medicine and surgery 20081001 |
Comparison of posaconazole and voriconazole in vitro killing against Candida krusei. | Diagnostic microbiology and infectious disease 20081001 |
Activities of antifungal agents against yeasts and filamentous fungi: assessment according to the methodology of the European Committee on Antimicrobial Susceptibility Testing. | Antimicrobial agents and chemotherapy 20081001 |
Posaconazole combined with amphotericin B, an effective therapy for a murine disseminated infection caused by Rhizopus oryzae. | Antimicrobial agents and chemotherapy 20081001 |
Posaconazole: an oral triazole with an extended spectrum of activity. | The Annals of pharmacotherapy 20081001 |
Pharmacokinetics of oral posaconazole in neutropenic patients receiving chemotherapy for acute myelogenous leukemia or myelodysplastic syndrome. | Pharmacotherapy 20081001 |
Adverse drug events complicate antifungal therapy for pulmonary aspergilloma. | The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20081001 |
Posaconazole as salvage therapy in patients with invasive fungal infections after solid organ transplant. | Transplantation 20080927 |
Does pre-exposure of Aspergillus fumigatus to voriconazole or posaconazole in vitro affect its virulence and the in vivo activity of subsequent posaconazole or voriconazole, respectively? A study in a fly model of aspergillosis. | The Journal of antimicrobial chemotherapy 20080901 |
Investigation and management of an outbreak of mucormycosis in a paediatric oncology unit. | The Journal of hospital infection 20080901 |
Trends in species distribution and susceptibility of bloodstream isolates of Candida collected in Monterrey, Mexico, to seven antifungal agents: results of a 3-year (2004 to 2007) surveillance study. | Journal of clinical microbiology 20080901 |
Breakpoints for posaconazole susceptibility testing: background and discussion about the need of establishing values. | Mycoses 20080901 |
Posaconazole for paediatric patients: status of development and future perspectives. | Mycoses 20080901 |
Invasive candidiasis in the ICU: evidence based and on the edge of evidence. | Mycoses 20080901 |
Posaconazole in intensive care patients I: invasive fungal infections in surgical intensive care and case presentation. | Mycoses 20080901 |
Comparative in vitro activities of posaconazole, voriconazole, itraconazole, and amphotericin B against Aspergillus and Rhizopus, and synergy testing for Rhizopus. | Medical mycology 20080901 |
In vitro susceptibilities of invasive isolates of Candida species: rapid increase in rates of fluconazole susceptible-dose dependent Candida glabrata isolates. | Antimicrobial agents and chemotherapy 20080801 |
Breakthrough disseminated Scedosporium prolificans infection in a patient with relapsed leukaemia on prolonged voriconazole followed by posaconazole prophylaxis. | Mycopathologia 20080801 |
Treatment of aspergillosis. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080801 |
[In vitro susceptibility of isolates of Scytalidium spp. from superficial lesions against posaconazole]. | Pathologie-biologie 20080701 |
MICs and minimum fungicidal concentrations of posaconazole, voriconazole and fluconazole for Cryptococcus neoformans and Cryptococcus gattii. | The Journal of antimicrobial chemotherapy 20080701 |
Posaconazole enhances the activity of amphotericin B against hyphae of zygomycetes in vitro. | Antimicrobial agents and chemotherapy 20080701 |
In vitro susceptibility of Cryptococcus gattii clinical isolates. | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20080701 |
In vitro antifungal susceptibility and molecular characterization of clinical isolates of Fusarium verticillioides (F. moniliforme) and Fusarium thapsinum. | Antimicrobial agents and chemotherapy 20080601 |
Posaconazole against Candida glabrata isolates with various susceptibilities to fluconazole. | Antimicrobial agents and chemotherapy 20080601 |
[New systemic antifungal drugs]. | La Revue de medecine interne 20080601 |
Numbers needed to treat with posaconazole prophylaxis to prevent invasive fungal infection and death. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080515 |
The effect of gastric Acid on the absorption of posaconazole. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080515 |
Posaconazole (Noxafil, SCH 56592), a new azole antifungal drug, was a discovery based on the isolation and mass spectral characterization of a circulating metabolite of an earlier lead (SCH 51048). | Journal of mass spectrometry : JMS 20080401 |
Multilaboratory testing of antifungal combinations against a quality control isolate of Candida krusei. | Antimicrobial agents and chemotherapy 20080401 |
Mucormycoses: serious complication of high-dose corticosteroid therapy for traumatic optic neuropathy. | International journal of oral and maxillofacial surgery 20080401 |
Therapeutic drug monitoring of antifungals: pharmacokinetic and pharmacodynamic considerations. | Therapeutic drug monitoring 20080401 |
Beta-D-glucan detection test: a step toward preemptive therapy for fungal infections in leukemic patients? | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080315 |
Novel antifungal agents as salvage therapy for invasive aspergillosis in patients with hematologic malignancies: posaconazole compared with high-dose lipid formulations of amphotericin B alone or in combination with caspofungin. | Leukemia 20080301 |
In vitro activities of combinations of amphotericin B, posaconazole and four other agents against Rhizopus. | The Journal of antimicrobial chemotherapy 20080301 |
Interaction of amphotericin B lipid formulations and triazoles with human polymorphonuclear leucocytes for antifungal activity against Zygomycetes. | Mycoses 20080301 |
Successfully treated Candida krusei infection of the lumbar spine with combined caspofungin/posaconazole therapy. | Medical mycology 20080201 |
Effect of calcineurin inhibitors on posaconazole blood levels as measured by the MVista microbiological assay. | Antimicrobial agents and chemotherapy 20080201 |
Posaconazole activity against Candida glabrata after exposure to caspofungin or amphotericin B. | Antimicrobial agents and chemotherapy 20080201 |
Selection of a surrogate agent (fluconazole or voriconazole) for initial susceptibility testing of posaconazole against Candida spp.: results from a global antifungal surveillance program. | Journal of clinical microbiology 20080201 |
Mucormycosis peritonitis: more than 2 years of disease-free follow-up after posaconazole salvage therapy after failure of liposomal amphotericin B. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20080201 |
Broad-spectrum antifungal prophylaxis in patients with cancer at high risk for invasive mold infections: point. | Journal of the National Comprehensive Cancer Network : JNCCN 20080201 |
Broad-spectrum antifungal prophylaxis in patients with cancer at high risk for invasive mold infections: counterpoint. | Journal of the National Comprehensive Cancer Network : JNCCN 20080201 |
[Antifungal activity of posaconazole and caspofungin in yeast causing invasive fungal infection (2002-2003). E-test system evaluation]. | Enfermedades infecciosas y microbiologia clinica 20080201 |
Comparison of disc diffusion assay with the CLSI reference method (M27-A2) for testing in vitro posaconazole activity against common and uncommon yeasts. | The Journal of antimicrobial chemotherapy 20080101 |
Treatment of zygomycosis: current and new options. | The Journal of antimicrobial chemotherapy 20080101 |
Progressive fusariosis: unpredictable posaconazole bioavailability, and feasibility of recombinant interferon-gamma plus granulocyte macrophage-colony stimulating factor for refractory disseminated infection. | Leukemia & lymphoma 20080101 |
Posaconazole : a review of its use in the prophylaxis of invasive fungal infections. | Drugs 20080101 |
Antifungal agents--clinical pharmacokinetics and drug interactions. | Mycoses 20080101 |
Development and validation of a high-performance liquid chromatography assay for posaconazole utilizing solid-phase extraction. | Clinical chemistry and laboratory medicine 20080101 |
Reviews of anti-infective agents: posaconazole: a broad-spectrum triazole antifungal agent. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20071215 |
Efficacy of caspofungin and posaconazole in a murine model of disseminated Exophiala infection. | Medical mycology 20071201 |
Pharmacokinetics of oral posaconazole in allogeneic hematopoietic stem cell transplant recipients with graft-versus-host disease. | Pharmacotherapy 20071201 |
A review of the new antifungals: posaconazole, micafungin, and anidulafungin. | Journal of drugs in dermatology : JDD 20071201 |
[Invasive zygomycosis in patients treated for haematological malignancies]. | Nederlands tijdschrift voor geneeskunde 20071124 |
Breakthrough infection of Trichosporon asahii during posaconazole treatment in a patient with acute myeloid leukaemia. | European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20071101 |
Efficacy of posaconazole and amphotericin B in experimental invasive pulmonary aspergillosis in dexamethasone immunosuppressed rats. | The Journal of antimicrobial chemotherapy 20071101 |
Correlation of posaconazole minimum fungicidal concentration and time kill test against nine Candida species. | The Journal of antimicrobial chemotherapy 20071101 |
Antifungal agents. | The Medical journal of Australia 20071001 |
Lack of cross-hepatotoxicity between voriconazole and posaconazole. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070915 |
Posaconazole therapy for chronic refractory coccidioidomycosis. | Chest 20070901 |
Synergistic effect of posaconazole and caspofungin against clinical zygomycetes. | Antimicrobial agents and chemotherapy 20070901 |
In vitro susceptibility to posaconazole of 1,903 yeast isolates recovered in France from 2003 to 2006 and tested by the method of the European committee on antimicrobial susceptibility testing. | Antimicrobial agents and chemotherapy 20070901 |
Early use of posaconazole in the successful treatment of rhino-orbital mucormycosis caused by Rhizopus oryzae. | The Journal of infection 20070901 |
Safety, tolerance, and efficacy of posaconazole therapy in patients with nonmeningeal disseminated or chronic pulmonary coccidioidomycosis. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070901 |
Posaconazole for invasive aspergillosis? | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070901 |
Recalcitrant Beauveria bassiana keratitis: confocal microscopy findings and treatment with posaconazole (Noxafil). | Cornea 20070901 |
Posaconazole: an extended-spectrum triazole antifungal agent. | Clinical therapeutics 20070901 |
In vitro susceptibilities of 217 clinical isolates of zygomycetes to conventional and new antifungal agents. | Antimicrobial agents and chemotherapy 20070701 |
Evaluation of Etest and disk diffusion methods compared with broth microdilution antifungal susceptibility testing of clinical isolates of Candida spp. against posaconazole. | Journal of clinical microbiology 20070601 |
Clinical evaluation of the Sensititre YeastOne plate for testing susceptibility of filamentous fungi to posaconazole. | Journal of clinical microbiology 20070601 |
Multicenter evaluation of a new disk agar diffusion method for susceptibility testing of filamentous fungi with voriconazole, posaconazole, itraconazole, amphotericin B, and caspofungin. | Journal of clinical microbiology 20070601 |
Posaconazole salvage therapy allows successful allogeneic hematopoietic stem cell transplantation in patients with refractory invasive mold infections. | Transplant infectious disease : an official journal of the Transplantation Society 20070601 |
Successful treatment of disseminated fusariosis with posaconazole during neutropenia and subsequent allogeneic hematopoietic stem cell transplantation. | Transplant infectious disease : an official journal of the Transplantation Society 20070601 |
Inherited long QT syndrome revealed by antifungals drug-drug interaction. | Journal of clinical pharmacy and therapeutics 20070601 |
Posaconazole: a new broad-spectrum antifungal agent. | Expert opinion on pharmacotherapy 20070601 |
Effect of oral posaconazole on the pharmacokinetics of cyclosporine and tacrolimus. | Pharmacotherapy 20070601 |
Drug interaction assessment following concomitant administration of posaconazole and phenytoin in healthy men. | Current medical research and opinion 20070601 |
Antimicrobial susceptibility of Fusarium, Aspergillus, and other filamentous fungi isolated from keratitis. | Archives of ophthalmology (Chicago, Ill. : 1960) 20070601 |
Rhino-orbital mucormycosis causing cavernous sinus and internal carotid thrombosis treated with posaconazole. | Archives of ophthalmology (Chicago, Ill. : 1960) 20070601 |
Posaconazole: a next-generation triazole antifungal. | Future microbiology 20070601 |
Posaconazole for the management of mucosal candidiasis. | Future microbiology 20070601 |
Posaconazole prophylaxis in hematologic cancer. | The New England journal of medicine 20070524 |
Posaconazole prophylaxis in hematologic cancer. | The New England journal of medicine 20070524 |
Posaconazole prophylaxis in hematologic cancer. | The New England journal of medicine 20070524 |
Posaconazole prophylaxis in hematologic cancer. | The New England journal of medicine 20070524 |
Posaconazole treatment for Apophysomyces elegans rhino-orbital zygomycosis following trauma for a male with well-controlled diabetes. | Journal of clinical microbiology 20070501 |
Rhizopus microsporus var. rhizopodiformis sinus-orbital zygomycosis in an immunosuppressed patient: successful treatment with posaconazole after a complicated clinical course. | Journal of medical microbiology 20070501 |
Mucormycosis in patients with complicated cirrhosis. | Singapore medical journal 20070501 |
Therapeutic efficacy of posaconazole against isolates of Candida albicans with different susceptibilities to fluconazole in a vaginal model. | Medical mycology 20070501 |
Posaconazole susceptibility testing against Candida species: comparison of broth microdilution and E-test methods. | Mycoses 20070501 |
[Correlations among itraconazole, voriconazole and posaconazole MICs in Aspergillus fumigatus]. | Enfermedades infecciosas y microbiologia clinica 20070501 |
Posaconazole for azole-refractory candidiasis in patients with HIV infection. | AIDS alert 20070501 |
Salvage treatment of histoplasmosis with posaconazole. | The Journal of infection 20070401 |
The Anti-Trypanosoma cruzi activity of posaconazole in a murine model of acute Chagas' disease is less dependent on gamma interferon than that of benznidazole. | Antimicrobial agents and chemotherapy 20070401 |
Evaluation of disk diffusion and Etest compared to broth microdilution for antifungal susceptibility testing of posaconazole against clinical isolates of filamentous fungi. | Journal of clinical microbiology 20070401 |
Autologous transplantation of CD133 selected hematopoietic progenitor cells for treatment of relapsed acute lymphoblastic leukemia. | Pediatric blood & cancer 20070301 |
Posaconazole plasma concentrations in juvenile patients with invasive fungal infection. | Antimicrobial agents and chemotherapy 20070301 |
Evaluation of the pharmacokinetics of posaconazole and rifabutin following co-administration to healthy men. | Current medical research and opinion 20070301 |
Posaconazole. | Nature reviews. Drug discovery 20070301 |
Successful treatment and limb salvage of mucor necrotizing fasciitis after kidney transplantation with posaconazole. | Hawaii medical journal 20070301 |
Posaconazole for the treatment of azole-refractory oropharyngeal and esophageal candidiasis in subjects with HIV infection. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070215 |
Effects of age, gender, and race/ethnicity on the pharmacokinetics of posaconazole in healthy volunteers. | Antimicrobial agents and chemotherapy 20070201 |
Posaconazole enhances the activity of amphotericin B against Aspergillus hyphae in vitro. | Antimicrobial agents and chemotherapy 20070201 |
Posaconazole as salvage therapy in a patient with disseminated zygomycosis: case report and review of the literature. | Pharmacotherapy 20070201 |
Successful treatment of resistant ocular fusariosis with posaconazole (SCH-56592). | American journal of ophthalmology 20070201 |
Drug approvals. | The Nurse practitioner 20070201 |
[The latest data on posaconazole]. | Medecine et maladies infectieuses 20070201 |
Possible increase of the neurotoxicity of vincristine by the concurrent use of posaconazole in a young adult with leukemia. | Journal of pediatric hematology/oncology 20070201 |
Posaconazole or fluconazole for prophylaxis in severe graft-versus-host disease. | The New England journal of medicine 20070125 |
Posaconazole vs. fluconazole or itraconazole prophylaxis in patients with neutropenia. | The New England journal of medicine 20070125 |
Prophylaxis and aspergillosis--has the principle been proven? | The New England journal of medicine 20070125 |
A sensitive liquid chromatography and mass spectrometry method for the determination of posaconazole in human plasma. | Journal of pharmaceutical and biomedical analysis 20070104 |
Posaconazole prophylaxis in experimental systemic zygomycosis. | Antimicrobial agents and chemotherapy 20070101 |
Quality control limits for posaconazole disk susceptibility tests on Mueller-Hinton agar with glucose and methylene blue. | Journal of clinical microbiology 20070101 |
Treatment of invasive aspergillosis with posaconazole in patients who are refractory to or intolerant of conventional therapy: an externally controlled trial. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070101 |
Safety and efficacy of posaconazole in the long-term treatment of azole-refractory oropharyngeal and esophageal candidiasis in patients with HIV infection. | HIV clinical trials 20070101 |
Rhinocerebral mucormycosis with perineural spread. | Ophthalmic plastic and reconstructive surgery 20070101 |
Changing epidemiology of rare mould infections: implications for therapy. | Drugs 20070101 |
Update on new antifungal therapy. | AACN advanced critical care 20070101 |
Successful treatment of pulmonary zygomycosis with posaconazole in a recipient of a haploidentical donor stem cell transplant. | Pediatric blood & cancer 20061201 |
Antifungal susceptibilities of the species of the Pseudallescheria boydii complex. | Antimicrobial agents and chemotherapy 20061201 |
Posaconazole (Noxafil) for invasive fungal infections. | The Medical letter on drugs and therapeutics 20061120 |
Evaluation of automated micro solid phase extraction tips (micro-SPE) for the validation of a LC-MS/MS bioanalytical method. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061107 |
Molecular basis for enhanced activity of posaconazole against Absidia corymbifera and Rhizopus oryzae. | Antimicrobial agents and chemotherapy 20061101 |
Chronic refractory phaeohyphomycosis: successful treatment with posaconazole. | Mycoses 20061101 |
Multi-azole resistance in Aspergillus fumigatus. | International journal of antimicrobial agents 20061101 |
New agents for the treatment of fungal infections: clinical efficacy and gaps in coverage. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20061015 |
Comparison of three commercial assays and a modified disk diffusion assay with two broth microdilution reference assays for testing zygomycetes, Aspergillus spp., Candida spp., and Cryptococcus neoformans with posaconazole and amphotericin B. | Journal of clinical microbiology 20061001 |
Successful use of posaconazole in a pediatric case of fungal necrotizing fasciitis. | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20060901 |
Comparison of the EUCAST-AFST broth dilution method with the CLSI reference broth dilution method (M38-A) for susceptibility testing of posaconazole and voriconazole against Aspergillus spp. | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20060901 |
Treatment of cavitary pulmonary zygomycosis with surgical resection and posaconazole. | The Annals of thoracic surgery 20060701 |
Interaction between posaconazole and caspofungin in concomitant treatment of mice with systemic Aspergillus infection. | Antimicrobial agents and chemotherapy 20060701 |
Periorbital zygomycosis (mucormycosis) treated with posaconazole. | American journal of ophthalmology 20060701 |
First case of Penicillium marneffei fungemia in Greece and strain susceptibility to five licensed systemic antifungal agents and posaconazole. | The American journal of the medical sciences 20060701 |
Safety of long-term oral posaconazole use in the treatment of refractory invasive fungal infections. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060615 |
Cytoskeleton reassembly in cardiomyocytes infected by Trypanosoma cruzi is triggered by treatment with ergosterol biosynthesis inhibitors. | International journal of antimicrobial agents 20060601 |
Pharmacokinetics and safety of oral posaconazole in neutropenic stem cell transplant recipients. | Antimicrobial agents and chemotherapy 20060601 |
In vitro activities of posaconazole, fluconazole, itraconazole, voriconazole, and amphotericin B against a large collection of clinically important molds and yeasts. | Antimicrobial agents and chemotherapy 20060601 |
In vitro activities of 10 combinations of antifungal agents against the multiresistant pathogen Scopulariopsis brevicaulis. | Antimicrobial agents and chemotherapy 20060601 |
Newer triazole antifungal agents: pharmacology, spectrum, clinical efficacy and limitations. | Expert opinion on investigational drugs 20060601 |
Importance of identification of zygomycetes in the era of newer antifungal agents. | Transplant infectious disease : an official journal of the Transplantation Society 20060601 |
Correlation between microdilution, E-test, and disk diffusion methods for antifungal susceptibility testing of posaconazole against Candida spp. | Journal of clinical microbiology 20060601 |
Posaconazole as salvage treatment for invasive fusariosis in patients with underlying hematologic malignancy and other conditions. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060515 |
Effect of a nutritional supplement on posaconazole pharmacokinetics following oral administration to healthy volunteers. | Antimicrobial agents and chemotherapy 20060501 |
Control of a Candida glabrata prosthetic endovascular infection with posaconazole. | Medical mycology 20060501 |
A multicenter randomized trial evaluating posaconazole versus fluconazole for the treatment of oropharyngeal candidiasis in subjects with HIV/AIDS. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060415 |
Oropharyngeal candidiasis: a new treatment option. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060415 |
Posaconazole is effective as salvage therapy in zygomycosis: a retrospective summary of 91 cases. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060401 |
Head-to-head comparison of the activities of currently available antifungal agents against 3,378 Spanish clinical isolates of yeasts and filamentous fungi. | Antimicrobial agents and chemotherapy 20060301 |
Evaluation of disk diffusion method for determining posaconazole susceptibility of filamentous fungi: comparison with CLSI broth microdilution method. | Antimicrobial agents and chemotherapy 20060301 |
Amiodarone has intrinsic anti-Trypanosoma cruzi activity and acts synergistically with posaconazole. | Journal of medicinal chemistry 20060209 |
Pharmacokinetics, safety, and efficacy of posaconazole in patients with persistent febrile neutropenia or refractory invasive fungal infection. | Antimicrobial agents and chemotherapy 20060201 |
Hydroxylated analogues of the orally active broad spectrum antifungal, Sch 51048 (1), and the discovery of posaconazole [Sch 56592; 2 or (S,S)-5]. | Bioorganic & medicinal chemistry letters 20060101 |
Posaconazole as salvage therapy for zygomycosis. | Antimicrobial agents and chemotherapy 20060101 |
Epidemiology of candidaemia and antifungal susceptibility patterns in an Italian tertiary-care hospital. | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20060101 |
Use of posaconazole in the management of invasive orbital aspergillosis in a cat. | Journal of the American Animal Hospital Association 20060101 |
A new, broad-spectrum azole antifungal: posaconazole--mechanisms of action and resistance, spectrum of activity. | Mycoses 20060101 |
Antifungal efficacy and pharmacodynamics of posaconazole in experimental models of invasive fungal infections. | Mycoses 20060101 |
HPLC analysis of the antifungal agent posaconazole in patients with haematological diseases. | Mycoses 20060101 |
Second-line treatment in invasive mould infections. | Mycoses 20060101 |
Successful treatment of disseminated mucormycosis with a combination of liposomal amphotericin B and posaconazole in a patient with acute myeloid leukaemia. | Mycoses 20060101 |
Rhinocerebral zygomycosis in a young girl undergoing allogeneic stem cell transplantation for severe aplastic anaemia. | Mycoses 20060101 |
Posaconazole for treatment of refractory invasive fungal disease. | Mycoses 20060101 |
Salvage therapy of refractory chronic disseminated candidiasis in a patient with acute myeloid leukaemia and secondary prophylaxis during allogeneic stem cell transplantation. | Mycoses 20060101 |
New drugs: ranibizumab, posaconazole, and darunavir. | Journal of the American Pharmacists Association : JAPhA 20060101 |
Novel medicine to prevent fungal infections. | FDA consumer 20060101 |
Posaconazole: a broad-spectrum triazole antifungal. | The Lancet. Infectious diseases 20051201 |
Pulmonary mucormycosis (zygomycosis) in a lung transplant recipient: recovery after posaconazole therapy. | Transplantation 20051115 |
Posaconazole therapy for systemic coccidioidomycosis in a chimpanzee (Pan troglodytes): a case report. | Mycoses 20051101 |
Mucormycoses in patients with hematologic malignancies: an emerging fungal infection. | Haematologica 20051101 |
What does 'culture of life' mean for an undocumented immigrant? | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20051015 |
Activity of posaconazole in the treatment of central nervous system fungal infections. | The Journal of antimicrobial chemotherapy 20051001 |
Quality control and reference guidelines for CLSI broth microdilution susceptibility method (M 38-A document) for amphotericin B, itraconazole, posaconazole, and voriconazole. | Journal of clinical microbiology 20051001 |
Advances in antifungal therapy. | The Pediatric infectious disease journal 20051001 |
Absidia posttraumatic infection: successful treatment with posaconazole. | The Journal of infection 20051001 |
A case of disseminated histoplasmosis successfully treated with the investigational drug posaconazole. | The Journal of infection 20051001 |
Treatment of zygomycosis with posaconazole in a patient with acute myeloid leukemia. | Clinical advances in hematology & oncology : H&O 20051001 |
Review of treatment of zygomycosis with posaconazole in a patient with acute myeloid leukemia. | Clinical advances in hematology & oncology : H&O 20051001 |
Comparison of visual 24-hour and spectrophotometric 48-hour MICs to CLSI reference microdilution MICs of fluconazole, itraconazole, posaconazole, and voriconazole for Candida spp.: a collaborative study. | Journal of clinical microbiology 20050901 |
[Physiological comportment and in vivo sensitivity of Sporothrix schenckii isolates maintained for 18 years by two preservation methods]. | Revista iberoamericana de micologia 20050901 |
Pulmonary mucormycosis (zygomycosis) in a lung transplant recipient: recovery after posaconazole therapy. | Transplantation 20050827 |
In vitro interaction of posaconazole and caspofungin against clinical isolates of Candida glabrata. | Antimicrobial agents and chemotherapy 20050801 |
International and multicenter comparison of EUCAST and CLSI M27-A2 broth microdilution methods for testing susceptibilities of Candida spp. to fluconazole, itraconazole, posaconazole, and voriconazole. | Journal of clinical microbiology 20050801 |
Lung infection due to opportunistic fungus, Phialemonium obovatum, in a bone marrow transplant recipient: an emerging infection with fungemia and Crohn disease-like involvement of the gastrointestinal tract. | Annals of diagnostic pathology 20050801 |
Posaconazole: clinical pharmacology and potential for management of fungal infections. | Expert review of anti-infective therapy 20050801 |
Refractory coccidioidomycosis treated with posaconazole. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050615 |
Effect of media composition and in vitro activity of posaconazole, caspofungin and voriconazole against zygomycetes. | The Journal of antimicrobial chemotherapy 20050601 |
Posaconazole as salvage therapy in patients with chronic granulomatous disease and invasive filamentous fungal infection. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050601 |
Antifungal agents in children. | Pediatric clinics of North America 20050601 |
Posaconazole. | Drugs of today (Barcelona, Spain : 1998) 20050601 |
In vitro activities of new and established triazoles against opportunistic filamentous and dimorphic fungi. | Medical mycology 20050501 |
Antifungal activity of posaconazole compared with fluconazole and amphotericin B against yeasts from oropharyngeal candidiasis and other infections. | The Journal of antimicrobial chemotherapy 20050301 |
In vitro activities of posaconazole, ravuconazole, terbinafine, itraconazole and fluconazole against dermatophyte, yeast and non-dermatophyte species. | Medical mycology 20050301 |
Posaconazole pharmacokinetics, safety, and tolerability in subjects with varying degrees of chronic renal disease. | Journal of clinical pharmacology 20050201 |
Interaction between posaconazole and amphotericin B in concomitant treatment against Candida albicans in vivo. | Antimicrobial agents and chemotherapy 20050201 |
Detection of Aspergillus fumigatus and a mutation that confers reduced susceptibility to itraconazole and posaconazole by real-time PCR and pyrosequencing. | Journal of clinical microbiology 20050201 |
Successful therapy of cerebral phaeohyphomycosis due to Ramichloridium mackenziei with the new triazole posaconazole. | Medical mycology 20050201 |
Oral bioavailability of posaconazole in fasted healthy subjects: comparison between three regimens and basis for clinical dosage recommendations. | Clinical pharmacokinetics 20050101 |
Posaconazole. | Drugs 20050101 |
Posaconazole treatment of refractory eumycetoma and chromoblastomycosis. | Revista do Instituto de Medicina Tropical de Sao Paulo 20050101 |
Successful treatment of Fusarium proliferatum pneumonia with posaconazole in a lung transplant recipient. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20041201 |
Aspergillus terreus: an emerging amphotericin B-resistant opportunistic mold in patients with hematologic malignancies. | Cancer 20041001 |
Posaconazole is a potent inhibitor of sterol 14alpha-demethylation in yeasts and molds. | Antimicrobial agents and chemotherapy 20041001 |
Antifungal activities of posaconazole and granulocyte-macrophage colony-stimulating factor ex vivo and in mice with disseminated infection due to Scedosporium prolificans. | Antimicrobial agents and chemotherapy 20041001 |
Efficacy of posaconazole in a murine model of central nervous system aspergillosis. | Antimicrobial agents and chemotherapy 20041001 |
Clinical evaluation of the Sensititre YeastOne colorimetric antifungal plate for antifungal susceptibility testing of the new triazoles voriconazole, posaconazole, and ravuconazole. | Journal of clinical microbiology 20041001 |
Posaconazole and amphotericin B combination therapy against Cryptococcus neoformans infection. | Antimicrobial agents and chemotherapy 20040901 |
Disposition of posaconazole following single-dose oral administration in healthy subjects. | Antimicrobial agents and chemotherapy 20040901 |
Zygomycosis in neutropenic patients with past Aspergillus infection: a role for posaconazole? | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20040901 |
Alternatives to amphotericin B for Candida rugosa infection. | The Journal of antimicrobial chemotherapy 20040801 |
Effect of granulocyte colony-stimulating factor combination therapy on efficacy of posaconazole (SCH56592) in an inhalation model of murine pulmonary aspergillosis. | Antimicrobial agents and chemotherapy 20040801 |
Challenges in designing animal studies to detect antagonism of polyene activity. | Antimicrobial agents and chemotherapy 20040801 |
Use of fatty acid RPMI 1640 media for testing susceptibilities of eight Malassezia species to the new triazole posaconazole and to six established antifungal agents by a modified NCCLS M27-A2 microdilution method and Etest. | Journal of clinical microbiology 20040801 |
Application of real-time quantitative PCR to molecular analysis of Candida albicans strains exhibiting reduced susceptibility to azoles. | Antimicrobial agents and chemotherapy 20040601 |
Posaconazole therapy of disseminated phaeohyphomycosis in a murine model. | Antimicrobial agents and chemotherapy 20040601 |
Posaconazole: a potent, extended-spectrum triazole anti-fungal for the treatment of serious fungal infections. | International journal of clinical practice 20040601 |
Posaconazole therapy for severe abdominal candidiasis: a case report. | Revista iberoamericana de micologia 20040601 |
[Fulminant invasive fungal sinusitis in immunosuppressed hosts -- pathognomic presentation in MRI]. | RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 20040501 |
Effect of posaconazole on cytochrome P450 enzymes: a randomized, open-label, two-way crossover study. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040401 |
Activity of posaconazole combined with amphotericin B against Aspergillus flavus infection in mice: comparative studies in two laboratories. | Antimicrobial agents and chemotherapy 20040301 |
Pharmacokinetics of posaconazole coadministered with antacid in fasting or nonfasting healthy men. | Antimicrobial agents and chemotherapy 20040301 |
Aspergillus fumigatus empyema, arthritis, and calcaneal osteomyelitis in a lung transplant patient successfully treated with posaconazole. | Journal of clinical microbiology 20040301 |
In vitro activities of voriconazole, posaconazole, and fluconazole against 4,169 clinical isolates of Candida spp. and Cryptococcus neoformans collected during 2001 and 2002 in the ARTEMIS global antifungal surveillance program. | Diagnostic microbiology and infectious disease 20040301 |
Case study: posaconazole treatment of disseminated phaeohyphomycosis due to Exophiala spinifera. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040201 |
Three-dimensional models of wild-type and mutated forms of cytochrome P450 14alpha-sterol demethylases from Aspergillus fumigatus and Candida albicans provide insights into posaconazole binding. | Antimicrobial agents and chemotherapy 20040201 |
Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of posaconazole (Noxafil). | Drug metabolism and disposition: the biological fate of chemicals 20040201 |
Effect of food on the relative bioavailability of two oral formulations of posaconazole in healthy adults. | British journal of clinical pharmacology 20040201 |
Changes in susceptibility to posaconazole in clinical isolates of Candida albicans. | The Journal of antimicrobial chemotherapy 20040101 |
Reversible dilated cardiomyopathy related to amphotericin B therapy. | The Journal of antimicrobial chemotherapy 20040101 |
Pharmacodynamics of a new triazole, posaconazole, in a murine model of disseminated candidiasis. | Antimicrobial agents and chemotherapy 20040101 |
In vitro antifungal activities of anidulafungin and micafungin, licensed agents and the investigational triazole posaconazole as determined by NCCLS methods for 12,052 fungal isolates: review of the literature. | Revista iberoamericana de micologia 20031201 |
Activity of posaconazole in treatment of experimental disseminated zygomycosis. | Antimicrobial agents and chemotherapy 20031101 |
Pharmacokinetics, safety, and tolerability of oral posaconazole administered in single and multiple doses in healthy adults. | Antimicrobial agents and chemotherapy 20030901 |
[Invasive aspergillosis: clinical manifestations and treatment]. | Revista iberoamericana de micologia 20030901 |
Activities of caspofungin, itraconazole, posaconazole, ravuconazole, voriconazole, and amphotericin B against 448 recent clinical isolates of filamentous fungi. | Journal of clinical microbiology 20030801 |
New antifungal agents. | Dermatologic clinics 20030701 |
Mucormycosis (zygomycosis) in a heart-kidney transplant recipient: recovery after posaconazole therapy. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030601 |
[In vitro activity of fluconazole, voriconazole and posaconazole against Candida spp]. | Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20030601 |
Activity of posaconazole against Pseudallescheria boydii: in vitro and in vivo assays. | Antimicrobial agents and chemotherapy 20030401 |
In vitro susceptibility testing of filamentous fungi: comparison of Etest and reference M38-A microdilution methods for determining posaconazole MICs. | Diagnostic microbiology and infectious disease 20030401 |
Use of high-performance liquid chromatographic and microbiological analyses for evaluating the presence or absence of active metabolites of the antifungal posaconazole in human plasma. | Journal of chromatography. A 20030214 |
Mutations in Aspergillus fumigatus resulting in reduced susceptibility to posaconazole appear to be restricted to a single amino acid in the cytochrome P450 14alpha-demethylase. | Antimicrobial agents and chemotherapy 20030201 |
In vitro activities of voriconazole, posaconazole, and four licensed systemic antifungal agents against Candida species infrequently isolated from blood. | Journal of clinical microbiology 20030101 |
Posaconazole: SCH 56592. | Drugs in R&D 20030101 |
[In vitro activity of posaconazole against yeasts isolated in blood cultures]. | Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20021201 |
[Present status and future prospects of azole antifungal agents in Japan]. | The Japanese journal of antibiotics 20021201 |
Laboratory evaluation of new antifungal agents against rare and refractory mycoses. | Current opinion in infectious diseases 20021201 |
In vitro susceptibilities of cerebrospinal fluid isolates of Cryptococcus neoformans collected during a ten-year period against fluconazole, voriconazole and posaconazole (SCH56592). | Mycoses 20021101 |
Acremonium strictum pulmonary infection in a leukemic patient successfully treated with posaconazole after failure of amphotericin B. | European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20021101 |
In vitro activities of investigational triazoles against Fusarium species: effects of inoculum size and incubation time on broth microdilution susceptibility test results. | Antimicrobial agents and chemotherapy 20021001 |
Antifungal triazoles and polymorphonuclear leukocytes synergize to cause increased hyphal damage to Scedosporium prolificans and Scedosporium apiospermum. | Antimicrobial agents and chemotherapy 20020701 |
In vivo activity of posaconazole against Mucor spp. in an immunosuppressed-mouse model. | Antimicrobial agents and chemotherapy 20020701 |
Ocular and systemic posaconazole(SCH-56592) treatment of invasive Fusarium solani keratitis and endophthalmitis. | The British journal of ophthalmology 20020701 |
In vitro activity of three new triazoles and one echinocandin against Candida bloodstream isolates from cancer patients. | The Journal of antimicrobial chemotherapy 20020701 |
Treatment of Scedosporium apiospermum brain abscesses with posaconazole. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020615 |
E-test method for testing susceptibilities of Aspergillus spp. to the new triazoles voriconazole and posaconazole and to established antifungal agents: comparison with NCCLS broth microdilution method. | Journal of clinical microbiology 20020601 |
Effect of medium composition on static and cidal activity of amphotericin B, itraconazole, voriconazole, posaconazole and terbinafine against Aspergillus fumigatus: a multicenter study. | Journal of chemotherapy (Florence, Italy) 20020601 |
In vitro and in vivo activities of posaconazole against Coccidioides immitis. | Antimicrobial agents and chemotherapy 20020501 |
Clinical evaluation of a frozen commercially prepared microdilution panel for antifungal susceptibility testing of seven antifungal agents, including the new triazoles posaconazole, ravuconazole, and voriconazole. | Journal of clinical microbiology 20020501 |
Antifungal activities of posaconazole, ravuconazole, and voriconazole compared to those of itraconazole and amphotericin B against 239 clinical isolates of Aspergillus spp. and other filamentous fungi: report from SENTRY Antimicrobial Surveillance Program, 2000. | Antimicrobial agents and chemotherapy 20020401 |
Genotyping and antifungal susceptibility of human subgingival Candida albicans isolates. | Archives of oral biology 20020301 |
Mechanism of azole antifungal activity as determined by liquid chromatographic/mass spectrometric monitoring of ergosterol biosynthesis. | Journal of mass spectrometry : JMS 20020301 |
Azole cross-resistance in Aspergillus fumigatus. | Antimicrobial agents and chemotherapy 20020201 |
Simultaneous high-performance liquid chromatographic determination of SCH 59884 (phosphate ester prodrug of SCH 56592), SCH 207962 and SCH 56592 in dog plasma. | Journal of pharmaceutical and biomedical analysis 20020101 |
Activity of the new antifungal triazole, posaconazole, against Cryptococcus neoformans. | The Journal of antimicrobial chemotherapy 20011201 |
Aspergillus: rising frequency of clinical isolation and continued susceptibility to antifungal agents, 1994-1999. | Diagnostic microbiology and infectious disease 20011201 |
Evaluation of Etest method for determining posaconazole MICs for 314 clinical isolates of Candida species. | Journal of clinical microbiology 20011101 |
In vitro activity of posaconazole against clinical isolates of dermatophytes. | Journal of clinical microbiology 20011101 |
In vitro activities of posaconazole (Sch 56592) compared with those of itraconazole and fluconazole against 3,685 clinical isolates of Candida spp. and Cryptococcus neoformans. | Antimicrobial agents and chemotherapy 20011001 |
Antifungals: what's in the pipeline. | Current opinion in microbiology 20011001 |
In vitro antifungal activity of posaconazole against various pathogenic fungi. | International journal of antimicrobial agents 20010801 |
In vitro activities of four novel triazoles against Scedosporium spp. | Antimicrobial agents and chemotherapy 20010701 |
Structural characterization of the oxidative degradation products of an antifungal agent SCH 56592 by LC-NMR and LC-MS. | Journal of pharmaceutical and biomedical analysis 20010601 |
Treatment of histoplasmosis. | Seminars in respiratory infections 20010601 |
Interactions of posaconazole and flucytosine against Cryptococcus neoformans. | Antimicrobial agents and chemotherapy 20010501 |
Antifungal activity and pharmacokinetics of posaconazole (SCH 56592) in treatment and prevention of experimental invasive pulmonary aspergillosis: correlation with galactomannan antigenemia. | Antimicrobial agents and chemotherapy 20010301 |
Isolation and in vitro susceptibility to amphotericin B, itraconazole and posaconazole of voriconazole-resistant laboratory isolates of Aspergillus fumigatus. | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20010301 |
In vitro and in vivo activities of SCH 56592 (posaconazole), a new triazole antifungal agent, against Aspergillus and Candida. | Antimicrobial agents and chemotherapy 20000801 |
In vitro activities of the new antifungal triazole SCH 56592 against common and emerging yeast pathogens. | Antimicrobial agents and chemotherapy 20000101 |
In-vitro and in-vivo activities of SCH56592 against Cryptococcus neoformans. | The Journal of antimicrobial chemotherapy 19991201 |
[New antifungal drugs. Present and future]. | Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 19990901 |
Current and emerging azole antifungal agents. | Clinical microbiology reviews 19990101 |
In vitro susceptibilities of Candida bloodstream isolates to the new triazole antifungal agents BMS-207147, Sch 56592, and voriconazole. | Antimicrobial agents and chemotherapy 19981201 |
Comparison of In vitro activities of the new triazole SCH56592 and the echinocandins MK-0991 (L-743,872) and LY303366 against opportunistic filamentous and dimorphic fungi and yeasts. | Journal of clinical microbiology 19981001 |
SCH56592 treatment of murine invasive aspergillosis. | The Journal of antimicrobial chemotherapy 19981001 |
In vitro activity of a new triazole antifungal agent, Sch 56592, against clinical isolates of filamentous fungi. | Mycopathologia 19980101 |
Activity of SCH 56592 compared with those of fluconazole and itraconazole against Candida spp. | Antimicrobial agents and chemotherapy 19971001 |
Activity of a new triazole, Sch 56592, compared with those of four other antifungal agents tested against clinical isolates of Candida spp. and Saccharomyces cerevisiae. | Antimicrobial agents and chemotherapy 19970201 |
In vitro studies of activities of the antifungal triazoles SCH56592 and itraconazole against Candida albicans, Cryptococcus neoformans, and other pathogenic yeasts. | Antimicrobial agents and chemotherapy 19970101 |
In vitro and in vivo efficacies of the azole SCH56592 against Cryptococcus neoformans. | Antimicrobial agents and chemotherapy 19960801 |