Home Other Building Blocks Dimemorfan phosphate

Dimemorfan phosphate

CAS No.:
36304-84-4
Catalog Number:
AG0039JX
Molecular Formula:
C18H28NO4P
Molecular Weight:
353.3930
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
50mg
99%
1 week
United States
$126
- +
100mg
99%
1 week
United States
$175
- +
Product Description
Catalog Number:
AG0039JX
Chemical Name:
Dimemorfan phosphate
CAS Number:
36304-84-4
Molecular Formula:
C18H28NO4P
Molecular Weight:
353.3930
MDL Number:
MFCD01714607
IUPAC Name:
(1S,9S,10S)-4,17-dimethyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-triene;phosphoric acid
InChI:
InChI=1S/C18H25N.H3O4P/c1-13-6-7-14-12-17-15-5-3-4-8-18(15,16(14)11-13)9-10-19(17)2;1-5(2,3)4/h6-7,11,15,17H,3-5,8-10,12H2,1-2H3;(H3,1,2,3,4)/t15-,17+,18+;/m1./s1
InChI Key:
ODJHDWLIOUGPPA-URVXVIKDSA-N
SMILES:
OP(=O)(O)O.Cc1ccc2c(c1)[C@]13CCCC[C@@H]3[C@@H](C2)N(CC1)C
EC Number:
252-958-6
UNII:
S203Y5Y1QP
Properties
Complexity:
401  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
3  
Defined Bond Stereocenter Count:
0
Exact Mass:
353.176g/mol
Formal Charge:
0
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
353.399g/mol
Monoisotopic Mass:
353.176g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
81A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
A new method for quantitative determination of dimemorfan in human plasma using monolithic silica solid-phase extraction tips. Legal medicine (Tokyo, Japan) 20120901
The oxidative metabolism of dimemorfan by human cytochrome P450 enzymes. Journal of pharmaceutical sciences 20100201
Anti-inflammatory effects of dimemorfan on inflammatory cells and LPS-induced endotoxin shock in mice. British journal of pharmacology 20080701
Concise synthesis of dimemorfan (DF) starting from 3-hydroxymorphinan (3-HM). Chemical & pharmaceutical bulletin 20080701
Dimemorfan protects rats against ischemic stroke through activation of sigma-1 receptor-mediated mechanisms by decreasing glutamate accumulation. Journal of neurochemistry 20080101
[Otorhinolaringologyc approach of the chronic cough. Clinical case]. Anales otorrinolaringologicos ibero-americanos 20070101
Dimemorfan N-demethylation by mouse liver microsomal cytochrome P450 enzymes. Life sciences 20050701
The dextromethorphan analog dimemorfan attenuates kainate-induced seizures via sigma1 receptor activation: comparison with the effects of dextromethorphan. British journal of pharmacology 20050401
Dimemorfan enhances acetylcholine release from rat hippocampal slices. Brain research 20040515
Dimemorfan prevents seizures induced by the L-type calcium channel activator BAY k-8644 in mice. Behavioural brain research 20040505
Anti-amnesic effect of dimemorfan in mice. British journal of pharmacology 20030301
Binding of dimemorfan to sigma-1 receptor and its anticonvulsant and locomotor effects in mice, compared with dextromethorphan and dextrorphan. Brain research 19990313
The nonnarcotic antitussive drug dimemorfan: a review. Clinical therapeutics 19970101
Effect of the centrally acting antitussives on ascites tumor cells. Japanese journal of pharmacology 19830401
Properties