1,3-Dimethyluric acid
| Title | Journal |
|---|---|
| Effect of decursin on the pharmacokinetics of theophylline and its metabolites in rats. | Journal of ethnopharmacology 20121121 |
| Effect of decursinol angelate on the pharmacokinetics of theophylline and its metabolites in rats. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121001 |
| Development and validation of a sensitive LC-MS/MS method for the simultaneous quantitation of theophylline and its metabolites in rat plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120315 |
| Metabolite profiling of Angelica gigas from different geographical origins using 1H NMR and UPLC-MS analyses. | Journal of agricultural and food chemistry 20110824 |
| Development and validation of a LC-MS/MS method based on a new 96-well Hybrid-SPE™-precipitation technique for quantification of CYP450 substrates/metabolites in rat plasma. | Analytical and bioanalytical chemistry 20110601 |
| Usefulness of the simultaneous determination of serum levels of theophylline and its metabolites in patients medicated with theophylline preparation. | Biomedical chromatography : BMC 20110401 |
| Nanosized rods agglomerates as a new approach for formulation of a dry powder inhaler. | International journal of nanomedicine 20110101 |
| Nitrosation of N-methyl derivatives of uric acid and their transnitrosation ability to N-acetylcysteine. | Chemical & pharmaceutical bulletin 20100901 |
| Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids. | Bioorganic & medicinal chemistry letters 20100101 |
| A synthetic uric acid analog accelerates cutaneous wound healing in mice. | PloS one 20100101 |
| Demethylation of theophylline (1,3-dimethylxanthine) to 1-methylxanthine: the first step of an antioxidising cascade. | Redox report : communications in free radical research 20100101 |
| Two distinct pathways for metabolism of theophylline and caffeine are coexpressed in Pseudomonas putida CBB5. | Journal of bacteriology 20090701 |
| Relaxing and contracting effects of theophylline's metabolites on the rabbit upper gastrointestinal tract. | Fundamental & clinical pharmacology 20081001 |
| Time-dependent effects of Klebsiella pneumoniae endotoxin (KPLPS) on the pharmacokinetics of theophylline in rats: return of the parameters in 96-hour KPLPS rats to the control levels. | Drug metabolism and disposition: the biological fate of chemicals 20080501 |
| [Population pharmacokinetic analysis of two theophylline formulations in premature neonates and infants with apnea]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080401 |
| Anti-inflammatory effect of theophylline in rats and its involvement of the glucocorticoid-glucocorticoid receptor system. | Journal of pharmacological sciences 20080401 |
| Effects of CYP inducers and inhibitors on the pharmacokinetics of intravenous theophylline in rats: involvement of CYP1A1/2 in the formation of 1,3-DMU. | The Journal of pharmacy and pharmacology 20080101 |
| Theophylline and its metabolites produce a stimulating cholinergic effect on the small intestine and a nonadrenergic noncholinergic relaxing effect on the colon: a comparative study in the rabbit intestine. | Journal of veterinary pharmacology and therapeutics 20071201 |
| Effects of water deprivation on the pharmacokinetics of theophylline and one of its metabolites, 1,3-dimethyluric acid, after intravenous and oral administration of aminophylline to rats. | Biopharmaceutics & drug disposition 20071101 |
| 7-Arylpiperazinylalkyl and 7-tetrahydroisoquinolinylalkyl derivatives of 8-alkoxy-purine-2,6-dione and some of their purine-2,6,8-trione analogs as 5-HT(1A), 5-HT(2A), and 5-HT(7) serotonin receptor ligands. | Bioorganic & medicinal chemistry 20070801 |
| Lack of effect of aciclovir on metabolism of theophylline and expression of hepatic cytochrome P450 1A2 in rats. | Biological & pharmaceutical bulletin 20070301 |
| Associations between CYP2E1 promoter polymorphisms and plasma 1,3-dimethyluric acid/theophylline ratios. | European journal of clinical pharmacology 20060801 |
| Effect of a newly developed ketolide antibiotic, telithromycin, on metabolism of theophylline and expression of cytochrome P450 in rats. | Life sciences 20060530 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Liver dysfunction markedly decreases the inhibition of cytochrome P450 1A2-mediated theophylline metabolism by fluvoxamine. | Clinical pharmacology and therapeutics 20060501 |
| Pharmacokinetics of theophylline in diabetes mellitus rats: induction of CYP1A2 and CYP2E1 on 1,3-dimethyluric acid formation. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050901 |
| Methylated purines in urinary stones. | Clinical chemistry 20050801 |
| Theophylline pharmacokinetics: comparison of Cyp1a1(-/-) and Cyp1a2(-/-) knockout mice, humanized hCYP1A1_1A2 knock-in mice lacking either the mouse Cyp1a1 or Cyp1a2 gene, and Cyp1(+/+) wild-type mice. | Pharmacogenetics and genomics 20050701 |
| Inhibition of theophylline metabolism by suplatast and its metabolites in rats. | Biological & pharmaceutical bulletin 20050601 |
| Cytochrome P450 enzyme-mediated drug metabolism at exposure to acute hypoxia (corresponding to an altitude of 4,500 m). | European journal of clinical pharmacology 20050301 |
| Uric acid may inhibit glucose-induced insulin secretion via binding to an essential arginine residue in rat pancreatic beta-cells. | Bioorganic & medicinal chemistry letters 20050215 |
| High-throughput liquid chromatography-tandem mass spectrometry assay for plasma theophylline and its metabolites. | Clinical chemistry 20041101 |
| Separation, pre-concentration, and HPLC analysis of methylxanthines in urine samples. | Journal of separation science 20041001 |
| Catabolism of caffeine in plants and microorganisms. | Frontiers in bioscience : a journal and virtual library 20040501 |
| Pharmacokinetics of intravenous theophylline in mutant Nagase analbuminemic rats. | Life sciences 20030131 |
| Effects of acute renal failure induced by uranyl nitrate on the pharmacokinetics of intravenous theophylline in rats: the role of CYP2E1 induction in 1,3-dimethyluric acid formation. | The Journal of pharmacy and pharmacology 20021201 |
| Structural basis for the binding affinity of xanthines with the DNA intercalator acridine orange. | Journal of medicinal chemistry 20011220 |
| Effect of alosetron on theophylline pharmacokinetics. | British journal of clinical pharmacology 20011101 |
| Use of novel solid-phase extraction sorbent materials for high-performance liquid chromatography quantitation of caffeine metabolism products methylxanthines and methyluric acids in samples of biological origin. | Journal of chromatography. B, Biomedical sciences and applications 20010815 |
| Caffeine metabolism before and after liver transplantation. | International journal of clinical pharmacology and therapeutics 20010201 |
| Caffeine metabolism in a group of 67 patients with primary biliary cirrhosis. | International journal of clinical pharmacology and therapeutics 20010101 |
| Dose dependent pharmacokinetics of theophylline: Michaelis-Menten parameters for its major metabolic pathways. | European journal of drug metabolism and pharmacokinetics 20010101 |
| Neurotoxic convulsions induced by theophylline and its metabolites in mice. | Biological & pharmaceutical bulletin 19960601 |
| Structure-activity relationships for the binding of ligands to xanthine or guanine phosphoribosyl-transferase from Toxoplasma gondii. | Biochemical pharmacology 19951109 |
| Kinetics of drug action in disease states. XVI. Pharmacodynamics of theophylline-induced seizures in rats. | The Journal of pharmacology and experimental therapeutics 19860301 |