Home Sulfos 10H-Phenothiazine-2-sulfonamide,N,N-dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-

10H-Phenothiazine-2-sulfonamide,N,N-dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-

CAS No.:
316-81-4
Catalog Number:
AG0039FQ
Molecular Formula:
C22H30N4O2S2
Molecular Weight:
446.6292
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Product Description
Catalog Number:
AG0039FQ
Chemical Name:
10H-Phenothiazine-2-sulfonamide,N,N-dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-
CAS Number:
316-81-4
Molecular Formula:
C22H30N4O2S2
Molecular Weight:
446.6292
MDL Number:
MFCD00867741
IUPAC Name:
N,N-dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine-2-sulfonamide
InChI:
InChI=1S/C22H30N4O2S2/c1-23(2)30(27,28)18-9-10-22-20(17-18)26(19-7-4-5-8-21(19)29-22)12-6-11-25-15-13-24(3)14-16-25/h4-5,7-10,17H,6,11-16H2,1-3H3
InChI Key:
VZYCZNZBPPHOFY-UHFFFAOYSA-N
SMILES:
CN1CCN(CC1)CCCN1c2ccccc2Sc2c1cc(cc2)S(=O)(=O)N(C)C
EC Number:
206-262-4
UNII:
YJ050AQ56X
Properties
Complexity:
661  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
446.181g/mol
Formal Charge:
0
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
446.628g/mol
Monoisotopic Mass:
446.181g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
80.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.7  
Literature
Title Journal
Using functional signatures to identify repositioned drugs for breast, myelogenous leukemia and prostate cancer. PLoS computational biology 20120201
[Phenothiazines are slowly oxidizable substrates of horseradish peroxidase]. Biomeditsinskaia khimiia 20110101
Methotrimeprazine-induced corneal deposits and cataract revealed by urine drug profiling test. Journal of Korean medical science 20101101
An overview of Indian research in schizophrenia. Indian journal of psychiatry 20100101
Research on antipsychotics in India. Indian journal of psychiatry 20100101
Relationship between obesity and antipsychotic drug use in the adult population: a longitudinal, retrospective claim database study in Primary Care settings. Neuropsychiatric disease and treatment 20080201
Simple and simultaneous determination for 12 phenothiazines in human serum by reversed-phase high-performance liquid chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070701
Analysis of phenothiazines in human body fluids using disk solid-phase extraction and liquid chromatography. Journal of AOAC International 20050101
Correlative neuroanatomical and neuropharmacological study of tremor and catatonia in the monkey. Neuropharmacology 19710501
The bucco-linguo-masticatory syndrome as a side-effect of neuroleptics therapy. The Psychiatric quarterly 19670101
Properties