Halofuginone inhibits multiple myeloma growth in vitro and in vivo and enhances cytotoxicity of conventional and novel agents.

British journal of haematology 20120601

TH17 cells are critical for skin-specific pathological injury in acute graft-versus-host disease.

Transplantation proceedings 20120601

Local inhibition of angiogenesis by halofuginone coated silicone materials.

Journal of materials science. Materials in medicine 20120501

Characterization of Plasmodium liver stage inhibition by halofuginone.

ChemMedChem 20120501

Reduction of burn scar formation by halofuginone-eluting silicone gel sheets: a controlled study on nude mice.

Annals of plastic surgery 20120301

Surgical stress resistance induced by single amino acid deprivation requires Gcn2 in mice.

Science translational medicine 20120125

Th17 response and inflammatory autoimmune diseases.

International journal of inflammation 20120101

Halofuginone down-regulates Smad3 expression and inhibits the TGFbeta-induced expression of fibrotic markers in human corneal fibroblasts.

Molecular vision 20120101

Altered tryptophan metabolism as a paradigm for good and bad aspects of immune privilege in chronic inflammatory diseases.

Frontiers in immunology 20120101

The immune diet: meeting the metabolic demands of lymphocyte activation.

F1000 biology reports 20120101

Involvement of host stroma cells and tissue fibrosis in pancreatic tumor development in transgenic mice.

PloS one 20120101

Determination of eleven coccidiostats in animal feed by liquid chromatography-tandem mass spectrometry at cross contamination levels.

Analytica chimica acta 20110826

Development and validation of a multi-residue liquid chromatography-tandem mass spectrometry confirmatory method for eleven coccidiostats in eggs.

Analytica chimica acta 20110826

[An absence of donor TH17 differentiation ameliorates dermal tissue damage].

Zhonghua yi xue za zhi 20110712

Efficacy of halofuginone lactate in the prevention of cryptosporidiosis in dairy calves.

The Veterinary record 20110514

[The role of Th17 cells in early onset of mice acute graft versus host disease].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110501

Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum.

PLoS genetics 20110401

Light-chain shuffling from an antigen-biased phage pool allows 185-fold improvement of an anti-halofuginone single-chain variable fragment.

Analytical biochemistry 20110301

Is there any synergic effect for coadministration of mitomycin C and halofuginone on the skin wound healing?

American journal of otolaryngology 20110101

Phase II AIDS Malignancy Consortium trial of topical halofuginone in AIDS-related Kaposi sarcoma.

Journal of acquired immune deficiency syndromes (1999) 20110101

Halofuginone and muscular dystrophy.

Histology and histopathology 20110101

Halofuginone-coated urethral catheters prevent periurethral spongiofibrosis in a rat model of urethral injury.

Journal of endourology 20110101

Identification of Baicalin as an immunoregulatory compound by controlling T(H)17 cell differentiation.

PloS one 20110101

How can natural products serve as a viable source of lead compounds for the development of new/novel anti-malarials?

Malaria journal 20110101

Natural products as starting points for future anti-malarial therapies: going back to our roots?

Malaria journal 20110101

The Ras antagonist, farnesylthiosalicylic acid (FTS), decreases fibrosis and improves muscle strength in dy/dy mouse model of muscular dystrophy.

PloS one 20110101

Illthrift in suckling lambs secondary to umbilical infections and possible implication of cryptosporidiosis as a risk factor.

Veterinary medicine international 20110101

Aberrant repair and fibrosis development in skeletal muscle.

Skeletal muscle 20110101

Th17 cells and IL-17 in protective immunity to vaginal candidiasis.

PloS one 20110101

Calf health from birth to weaning. II. Management of diarrhoea in pre-weaned calves.

Irish veterinary journal 20110101

Probiotics for the control of parasites: an overview.

Journal of parasitology research 20110101

Microarray profiling reveals the integrated stress response is activated by halofuginone in mammary epithelial cells.

BMC research notes 20110101

Halofuginone has anti-proliferative effects in acute promyelocytic leukemia by modulating the transforming growth factor beta signaling pathway.

PloS one 20110101

Efficacy of topical halofuginone in myringotomy patency.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20101101

Pharmacokinetic and tissue distribution of doxycycline in broiler chickens pretreated with either: diclazuril or halofuginone.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20101101

Inhibition of pancreatic stellate cell activation by halofuginone prevents pancreatic xenograft tumor development.

Pancreas 20101001

The effects of methylprednisolone and halofuginone on preventing esophageal and hypopharyngeal fibrosis in delivered radiotherapy.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20100901

Is feline acquired reactive perforating collagenosis a wound healing defect? Treatment with topical betamethasone and halofuginone appears beneficial.

Veterinary dermatology 20100801

Fibrosis inhibition and muscle histopathology improvement in laminin-alpha2-deficient mice.

Muscle & nerve 20100801

Surface modification of silicone breast implants by binding the antifibrotic drug halofuginone reduces capsular fibrosis.

Plastic and reconstructive surgery 20100701

Innovative therapies for systemic sclerosis.

Current opinion in rheumatology 20100501

Halofuginone inhibits Smad3 phosphorylation via the PI3K/Akt and MAPK/ERK pathways in muscle cells: effect on myotube fusion.

Experimental cell research 20100401

Radioprotectors and mitigators of radiation-induced normal tissue injury.

The oncologist 20100401

The antifibrotic drug halofuginone inhibits proliferation and collagen production by human leiomyoma and myometrial smooth muscle cells.

Fertility and sterility 20100301

Halofuginone, a specific inhibitor of collagen type 1 synthesis, ameliorates oxidant colonic damage in rats with experimental colitis.

Digestive diseases and sciences 20100301

Halofuginone enhances the radiation sensitivity of human tumor cell lines.

Cancer letters 20100301

Dihydroxylation of vinyl sulfones: stereoselective synthesis of (+)- and (-)-febrifugine and halofuginone.

The Journal of organic chemistry 20100115

Halofuginone- and chitosan-coated amnion membranes demonstrate improved abdominal adhesion prevention.

TheScientificWorldJournal 20100101

Oesophageal foreign bodies in dogs: factors affecting success of endoscopic retrieval.

Irish veterinary journal 20100101

Validation of a multi-residue liquid chromatography-tandem mass spectrometry confirmatory method for 10 anticoccidials in eggs according to Commission Decision 2002/657/EC.

Journal of chromatography. A 20091113

Multi-residue confirmatory method for the determination of twelve coccidiostats in chicken liver using liquid chromatography tandem mass spectrometry.

Journal of chromatography. A 20091113

Systematic review and meta-analyses of the effects of halofuginone against calf cryptosporidiosis.

Preventive veterinary medicine 20091001

Halofuginone mediated protection against radiation-induced leg contracture.

International journal of oncology 20090801

Combination of cell culture and quantitative PCR for screening of drugs against Cryptosporidium parvum.

Veterinary parasitology 20090610

Immunology. Amino acid addiction.

Science (New York, N.Y.) 20090605

Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response.

Science (New York, N.Y.) 20090605

Recent advances in the treatment of systemic sclerosis.

Clinical reviews in allergy & immunology 20090601

Inhibition of transforming growth factor beta signaling by halofuginone as a modality for pancreas fibrosis prevention.

Pancreas 20090501

Effectiveness of topically applied halofuginone in management of subglottic stenosis in rats.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20090501

Synthesis and comparison of antimalarial activity of febrifugine derivatives including halofuginone.

Medicinal chemistry (Shariqah (United Arab Emirates)) 20090501

Treatment of calf diarrhea: antimicrobial and ancillary treatments.

The Veterinary clinics of North America. Food animal practice 20090301

Halofuginone prevents extracellular matrix deposition in diabetic nephropathy.

Biochemical and biophysical research communications 20090206

Wound-healing modulation in upper airway stenosis-Myths and facts.

Head & neck 20090101

Anti-angiogenic effects of pterogynidine alkaloid isolated from Alchornea glandulosa.

BMC complementary and alternative medicine 20090101

Halofuginone has a beneficial effect on gentamicin-induced acute nephrotoxicity in rats.

Drug and chemical toxicology 20090101

Focus on collagen: in vitro systems to study fibrogenesis and antifibrosis state of the art.

Fibrogenesis & tissue repair 20090101

Targeting liver myofibroblasts: a novel approach in anti-fibrogenic therapy.

Hepatology international 20081201

Prevention of muscle fibrosis and improvement in muscle performance in the mdx mouse by halofuginone.

Neuromuscular disorders : NMD 20081101

An outbreak of cryptosporidiosis in a collection of Stone curlews (Burhinus oedicnemus) in Dubai.

Avian pathology : journal of the W.V.P.A 20081001

Myofibroblasts in pulmonary and brain metastases of alveolar soft-part sarcoma: a novel target for treatment?

Neoplasia (New York, N.Y.) 20080901

The effect of halofuginone, a specific inhibitor of collagen type 1 synthesis, in the prevention of pancreatic fibrosis in an experimental model of severe hyperstimulation and obstruction pancreatitis.

The Journal of surgical research 20080701

The preventive effect of halofuginone on posterior glottic stenosis in a rabbit model.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20080701

Halofuginone upregulates the expression of heparanase in thioacetamide-induced liver fibrosis in rats.

Laboratory investigation; a journal of technical methods and pathology 20080601

Functional resolution of fibrosis in mdx mouse dystrophic heart and skeletal muscle by halofuginone.

American journal of physiology. Heart and circulatory physiology 20080401

Focusing on fibrosis: halofuginone-induced functional improvement in the mdx mouse model of Duchenne muscular dystrophy.

American journal of physiology. Heart and circulatory physiology 20080401

Type I collagen expression contributes to angiogenesis and the development of deeply invasive cutaneous melanoma.

International journal of cancer 20080301

NF-kappa B: a new player in angiostatic therapy.

Angiogenesis 20080301

The liver pharmacological and xenobiotic gene response repertoire.

Molecular systems biology 20080101

Effect of halofuginone lactate on treatment and prevention of lamb cryptosporidiosis: an extensive field trial.

Journal of veterinary pharmacology and therapeutics 20071201

Involvement of ERK signaling in halofuginone-driven inhibition of fibroblast ability to contract collagen lattices.

European journal of pharmacology 20071114

(2R,3S)-(+)- and (2S,3R)-(-)-Halofuginone lactate: synthesis, absolute configuration, and activity against Cryptosporidium parvum.

Bioorganic & medicinal chemistry letters 20070801

Development and validation of a cell culture based assay for in vitro assessment of anticryptosporidial compounds.

Parasitology research 20070601

Gene expression during chemically induced liver fibrosis: effect of halofuginone on TGF-beta signaling.

Cell and tissue research 20070401

Evaluation of endotoxaemia in the prognosis and treatment of scouring merino lambs.

Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20070301

Inhibition of fibroblast to myofibroblast transition by halofuginone contributes to the chemotherapy-mediated antitumoral effect.

Molecular cancer therapeutics 20070201

Effects of halofuginone on fibrosis formation secondary to experimentally induced subglottic trauma.

The Laryngoscope 20070201

Halofuginone reduces the occurrence of renal fibrosis in 5/6 nephrectomized rats.

The Israel Medical Association journal : IMAJ 20070101

Potential therapeutical effects of topical halofuginone hydrobromide in keloid management.

Medical hypotheses 20070101

Effect of halofuginone, a collagen alpha1(I) inhibitor, on wound healing in normal and irradiated skin: implication for hematopoietic stem cell transplantation.

Acta haematologica 20070101

Evolving concepts of liver fibrogenesis provide new diagnostic and therapeutic options.

Comparative hepatology 20070101

Field study of the efficacy of halofuginone and decoquinate in the treatment of cryptosporidiosis in veal calves.

The Veterinary record 20061111

Hydrodynamics based transfection in normal and fibrotic rats.

World journal of gastroenterology 20061014

Halofuginone inhibits NF-kappaB and p38 MAPK in activated T cells.

Journal of leukocyte biology 20060801

Phase I and pharmacokinetic study of halofuginone, an oral quinazolinone derivative in patients with advanced solid tumours.

European journal of cancer (Oxford, England : 1990) 20060801

Halofuginone induces matrix metalloproteinases in rat hepatic stellate cells via activation of p38 and NFkappaB.

The Journal of biological chemistry 20060602

Involvement of the tyrosine phosphatase early gene of liver regeneration (PRL-1) in cell cycle and in liver regeneration and fibrosis effect of halofuginone.

Cell and tissue research 20060601

Halofuginone prevents subglottic stenosis in a canine model.

The Annals of otology, rhinology, and laryngology 20060501

Halofuginone suppresses the lung metastasis of chemically induced hepatocellular carcinoma in rats through MMP inhibition.

Neoplasia (New York, N.Y.) 20060401

Halofuginone inhibits tumor growth in the polyoma middle T antigen mouse via a thrombospondin-1 independent mechanism.

Cancer biology & therapy 20060201

Inhibition of rat renal fibroblast proliferation by halofuginone.

Nephron. Experimental nephrology 20060101

Drug-eluting stent: a review and update.

Vascular health and risk management 20051201

Incidence of residues of nine anticoccidials in eggs.

Food additives and contaminants 20051101

Inhibition of Wilms tumor xenograft progression by halofuginone is accompanied by activation of WT-1 gene expression.

The Journal of urology 20051001

Deposition and depletion of five anticoccidials in eggs.

Journal of agricultural and food chemistry 20050907

Prevention of esophageal strictures in a caustic burn model using halofuginone, an inhibitor of collagen type I synthesis.

The Laryngoscope 20050901

Halofuginone inhibits collagen deposition in fibrous capsules around implants.

Annals of plastic surgery 20050301

Screening for the coccidiostats halofuginone and nicarbazin in egg and chicken muscle: development of an ELISA.

Food additives and contaminants 20050201

Residue analysis for halofuginone in sturgeon muscle by immunoaffinity cleanup and liquid chromatography.

Journal of AOAC International 20050101

Efficient and sensitive detection of residues of nine coccidiostats in egg and muscle by liquid chromatography-electrospray tandem mass spectrometry.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225

Examination of antimicrobial activity of selected non-antibiotic drugs.

Acta poloniae pharmaceutica 20041201

Animal models of systemic sclerosis: insights into systemic sclerosis pathogenesis and potential therapeutic approaches.

Current opinion in rheumatology 20041101

Liquid chromatography-electrospray tandem mass spectrometric assay suitable for quantitation of halofuginone in plasma.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041015

Halofuginone can worsen liver fibrosis in bile duct obstructed rats.

Liver international : official journal of the International Association for the Study of the Liver 20041001

Halofuginone inhibits angiogenesis and growth in implanted metastatic rat brain tumor model--an MRI study.

Neoplasia (New York, N.Y.) 20040901

Suppression of hepatocellular carcinoma growth in mice by the alkaloid coccidiostat halofuginone.

European journal of cancer (Oxford, England : 1990) 20040601

Ureteral replacement using small-intestinal submucosa and a collagen inhibitor in a porcine model.

Journal of endourology 20040601

Potential nonhormonal therapeutics for medical treatment of leiomyomas.

Seminars in reproductive medicine 20040501

Amelioration of radiation-induced fibrosis: inhibition of transforming growth factor-beta signaling by halofuginone.

The Journal of biological chemistry 20040409

Smad3 as a mediator of the fibrotic response.

International journal of experimental pathology 20040401

Halofuginone, an inhibitor of collagen synthesis by rat stellate cells, stimulates insulin-like growth factor binding protein-1 synthesis by hepatocytes.

Journal of hepatology 20040201

The effect of halofuginone, a specific inhibitor of collagen type 1 synthesis, in the prevention of esophageal strictures related to caustic injury.

American journal of surgery 20040201

Determination of halofuginone in eggs by liquid chromatography/tandem mass spectrometry after cleanup with immunoaffinity chromatography.

Rapid communications in mass spectrometry : RCM 20040101

Halofuginone inhibits serum-stimulated pericardial tissue retraction in vitro.

Tissue engineering 20040101

The use of halofuginone in limiting urethral stricture formation and recurrence: an experimental study in rabbits.

The Journal of urology 20031101

Treatment with halofuginone results in marked growth inhibition of a von Hippel-Lindau pheochromocytoma in vivo.

Clinical cancer research : an official journal of the American Association for Cancer Research 20030901

Resistance to anticoccidial drugs of Dutch avian Eimeria spp. field isolates originating from 1996, 1999 and 2001.

Avian pathology : journal of the W.V.P.A 20030801

Halofuginone to treat fibrosis in chronic graft-versus-host disease and scleroderma.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20030701

Development and validation of a method for the confirmation of halofuginone in chicken liver and eggs using electrospray tandem mass spectrometry.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030505

The production and characterisation of an antibody to detect the coccidiostat toltrazuril and its metabolite ponazuril.

The Analyst 20030501

A medical compound derived from herbs.

Science (New York, N.Y.) 20030328

Prevalence and control of bovine cryptosporidiosis in German dairy herds.

Veterinary parasitology 20030325

Hepatitis C and liver fibrosis.

Cell death and differentiation 20030101

Hepatic fibrosis: from bench to bedside.

Journal of gastroenterology and hepatology 20021201

Halofuginone inhibition of COL1A2 promoter activity via a c-Jun-dependent mechanism.

Arthritis and rheumatism 20021001

Halofuginone, a collagen type I inhibitor improves liver regeneration in cirrhotic rats.

Journal of hepatology 20020901

Halofuginone does not reduce fibrosis in bleomycin-induced lung injury.

Life sciences 20020823

Effect of halofuginone on the development of tight skin (TSK) syndrome.

Autoimmunity 20020701

Angiogenesis in bladder cancer--prognostic marker and target for future therapy.

Surgical oncology 20020601

The production and characterisation of dinitrocarbanilide antibodies raised using antigen mimics.

Journal of immunological methods 20020601

Growth inhibition of prostate cancer xenografts by halofuginone.

The Prostate 20020501

Analysis of the effect of halofuginone on bleomycin-induced scleroderma.

Rheumatology (Oxford, England) 20020501

Halofuginone, an inhibitor of type-I collagen synthesis and skin sclerosis, blocks transforming-growth-factor-beta-mediated Smad3 activation in fibroblasts.

The Journal of investigative dermatology 20020301

Inhibition of anastomotic intimal hyperplasia by a synthetic nonsulphated heparin-mimicking compound.

Experimental and clinical cardiology 20020101

Reduction in dermal fibrosis in the tight-skin (Tsk) mouse after local application of halofuginone.

Biochemical pharmacology 20011101

Pharmacokinetics and tissue distribution of halofuginone (NSC 713205) in CD2F1 mice and Fischer 344 rats.

Cancer chemotherapy and pharmacology 20011101

Halofuginone to prevent and treat thioacetamide-induced liver fibrosis in rats.

Hepatology (Baltimore, Md.) 20010201

Novel therapy in the treatment of scleroderma.

Expert opinion on investigational drugs 20010101

Determination of halofuginone and amprolium in chicken muscle and egg by liquid chromatography.

Journal of AOAC International 20010101

Halofuginone: a potent inhibitor of critical steps in angiogenesis progression.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20001201

The activity of halofuginone in immunosuppressed rats infected with Cryptosporidium parvum.

The Journal of antimicrobial chemotherapy 19950301