Cichoric Acid
| Title | Journal |
|---|---|
| Chicoric acid is an antioxidant molecule that stimulates AMP kinase pathway in L6 myotubes and extends lifespan in Caenorhabditis elegans. | PloS one 20130101 |
| Cytotoxic effects of Echinacea purpurea flower extracts and cichoric acid on human colon cancer cells through induction of apoptosis. | Journal of ethnopharmacology 20121011 |
| Hydrolysis of chicoric and caftaric acids with esterases and Lactobacillus johnsonii in Vitro and in a gastrointestinal model. | Journal of agricultural and food chemistry 20120912 |
| Molecular dynamics approach to probe the allosteric inhibition of PTP1B by chlorogenic and cichoric acid. | Journal of chemical information and modeling 20120827 |
| Chicoric acid regulates behavioral and biochemical alterations induced by chronic stress in experimental Swiss albino mice. | Pharmacology, biochemistry, and behavior 20110901 |
| Inhibition of stromelysin-1 by caffeic acid derivatives from a propolis sample from Algeria. | Planta medica 20110701 |
| Luteolin and chicoric acid synergistically inhibited inflammatory responses via inactivation of PI3K-Akt pathway and impairment of NF-κB translocation in LPS stimulated RAW 264.7 cells. | European journal of pharmacology 20110625 |
| Augmentation of immune response by chicoric acid through the modulation of CD28/CTLA-4 and Th1 pathway in chronically stressed mice. | Neuropharmacology 20110501 |
| Taraxacum officinale Weber extracts inhibit LPS-induced oxidative stress and nitric oxide production via the NF-κB modulation in RAW 264.7 cells. | Journal of ethnopharmacology 20110127 |
| Analysis of eleven phenolic compounds including novel p-coumaroyl derivatives in lettuce (Lactuca sativa L.) by ultra-high-performance liquid chromatography with photodiode array and mass spectrometry detection. | Phytochemical analysis : PCA 20110101 |
| Computational fluid dynamics modeling of mass-transfer behavior in a bioreactor for hairy root culture. II. Analysis of ultrasound-intensified process. | Biotechnology progress 20110101 |
| Determination of major phenolic compounds in Echinacea spp. raw materials and finished products by high-performance liquid chromatography with ultraviolet detection: single-laboratory validation matrix extension. | Journal of AOAC International 20110101 |
| Design, synthesis, and biological evaluation of novel hybrid dicaffeoyltartaric/diketo acid and tetrazole-substituted L-chicoric acid analogue inhibitors of human immunodeficiency virus type 1 integrase. | Journal of medicinal chemistry 20101125 |
| Effect of high pressure pasteurization on bacterial load and bioactivity of Echinacea purpurea. | Journal of food science 20100901 |
| New 2-arylnaphthalenediols and triol inhibitors of HIV-1 integrase--discovery of a new polyhydroxylated antiviral agent. | Bioorganic & medicinal chemistry 20100715 |
| Botulinum neurotoxin A protease: discovery of natural product exosite inhibitors. | Journal of the American Chemical Society 20100310 |
| Environmental stresses induce health-promoting phytochemicals in lettuce. | Plant physiology and biochemistry : PPB 20090701 |
| Natural product inhibitors of protein-protein interactions mediated by Src-family SH2 domains. | Bioorganic & medicinal chemistry letters 20090615 |
| Chicoric acid, a new compound able to enhance insulin release and glucose uptake. | Biochemical and biophysical research communications 20081205 |
| The total synthesis of fukiic acid, an HIV-1 integrase inhibitor. | European journal of medicinal chemistry 20081001 |
| Synthesis and antiviral properties of some polyphenols related to Salvia genus. | Bioorganic & medicinal chemistry letters 20080815 |
| Echinacea alkylamides modulate induced immune responses in T-cells. | Fitoterapia 20080101 |
| Genomics and proteomics of immune modulatory effects of a butanol fraction of echinacea purpurea in human dendritic cells. | BMC genomics 20080101 |
| Caffeoylglycolic and caffeoylamino acid derivatives, halfmers of L-chicoric acid, as new HIV-1 integrase inhibitors. | European journal of medicinal chemistry 20071001 |
| Large-scale cultivation of adventitious roots of Echinacea purpurea in airlift bioreactors for the production of chichoric acid, chlorogenic acid and caftaric acid. | Biotechnology letters 20070801 |
| Design, synthesis, and biological evaluation of chicoric acid analogs as inhibitors of HIV-1 integrase. | Bioorganic & medicinal chemistry 20060701 |
| Genetic diversity in seed populations of Echinacea purpurea controls the capacity for regeneration, route of morphogenesis and phytochemical composition. | Plant cell reports 20060601 |
| Anti-human immunodeficiency virus activity of 3,4,5-tricaffeoylquinic acid in cultured cells of lettuce leaves. | Molecular nutrition & food research 20060401 |
| Vanillic acid glycoside and quinic acid derivatives from Gardeniae Fructus. | Journal of natural products 20060401 |
| Preparative separation of cichoric acid from Echinacea purpurea by pH-zone-refining counter-current chromatography. | Journal of chromatography. A 20060120 |
| Development and validation of a high-throughput based on liquid chromatography with ultraviolet absorption and mass spectrometry detection method for quantitation of cichoric acid in Echinacea purpurea aerial-based dietary supplements. | Journal of AOAC International 20060101 |
| Synergistic antioxidative effects of alkamides, caffeic acid derivatives, and polysaccharide fractions from Echinacea purpurea on in vitro oxidation of human low-density lipoproteins. | Journal of agricultural and food chemistry 20051130 |
| Human gene expression as a tool to determine horticultural maturity in a bioactive plant (Echinacea purpurea L. Moench). | Journal of agricultural and food chemistry 20051019 |
| Synthesis and biological evaluation of geminal disulfones as HIV-1 integrase inhibitors. | Journal of medicinal chemistry 20050714 |
| Anti-HIV activities of natural antioxidant caffeic acid derivatives: toward an antiviral supplementation diet. | Current medicinal chemistry 20050101 |
| [Technology of extract improving the immune system]. | Medicina (Kaunas, Lithuania) 20050101 |
| Profile of resistance of human immunodeficiency virus to mannose-specific plant lectins. | Journal of virology 20041001 |
| L-chicoric acid inhibits human immunodeficiency virus type 1 integration in vivo and is a noncompetitive but reversible inhibitor of HIV-1 integrase in vitro. | Virology 20040901 |
| HIV-1 integrase inhibitors: a decade of research and two drugs in clinical trial. | Current topics in medicinal chemistry 20040101 |
| Catechol-substituted L-chicoric acid analogues as HIV integrase inhibitors. | Bioorganic & medicinal chemistry letters 20031215 |
| HPLC method validated for the simultaneous analysis of cichoric acid and alkamides in Echinacea purpurea plants and products. | Journal of agricultural and food chemistry 20031119 |
| A new anti-HIV flavonoid glucuronide from Chrysanthemum morifolium. | Planta medica 20030901 |
| Caffeoyl naphthalenesulfonamide derivatives as HIV integrase inhibitors. | Bioorganic & medicinal chemistry 20030815 |
| Effect of drying temperature on alkylamide and cichoric acid concentrations of Echinacea purpurea. | Journal of agricultural and food chemistry 20030312 |
| Human immunodeficiency virus type-1 integrase containing a glycine to serine mutation at position 140 is attenuated for catalysis and resistant to integrase inhibitors. | Virology 20030201 |
| QSAR studies of HIV-1 integrase inhibition. | Bioorganic & medicinal chemistry 20021201 |
| Antiviral activity of characterized extracts from echinacea spp. (Heliantheae: Asteraceae) against herpes simplex virus (HSV-I). | Planta medica 20020901 |
| Dicaffeoyltartaric acid analogues inhibit human immunodeficiency virus type 1 (HIV-1) integrase and HIV-1 replication at nontoxic concentrations. | Journal of medicinal chemistry 20020815 |
| New class of HIV integrase inhibitors that block viral replication in cell culture. | Current biology : CB 20020723 |
| Stabilization of caffeic acid derivatives in Echinacea purpurea L. glycerin extract. | Journal of agricultural and food chemistry 20020703 |
| Phytochemical variation in echinacea from roots and flowerheads of wild and cultivated populations. | Journal of agricultural and food chemistry 20020619 |
| Simultaneous analysis of alkamides and caffeic acid derivatives for the identification of Echinacea purpurea, Echinacea angustifolia, Echinacea pallida and Parthenium integrifolium roots. | Planta medica 20020601 |
| [Determination of cichoric acid in Echinacea purpuea]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20020601 |
| Diketo acid inhibitor mechanism and HIV-1 integrase: implications for metal binding in the active site of phosphotransferase enzymes. | Proceedings of the National Academy of Sciences of the United States of America 20020514 |
| HIV-1 integrase inhibitory phenylpropanoid glycosides from Clerodendron trichotomum. | Archives of pharmacal research 20010801 |
| Dicaffeoyl- or digalloyl pyrrolidine and furan derivatives as HIV integrase inhibitors. | Bioorganic & medicinal chemistry 20010601 |
| Predicting quantitative phytochemical markers in single Echinacea plants or clones from their DNA fingerprints. | Phytochemistry 20010301 |
| [Chicoric and chlorogenic acids in various plants growing in Georgia]. | Prikladnaia biokhimiia i mikrobiologiia 20010101 |
| Viral entry as the primary target for the anti-HIV activity of chicoric acid and its tetra-acetyl esters. | Molecular pharmacology 20000901 |
| Synthesis and HIV-1 integrase inhibitory activities of caffeoylglucosides. | Bioorganic & medicinal chemistry letters 20000821 |
| Chicoric acid analogues as HIV-1 integrase inhibitors. | Journal of medicinal chemistry 19990422 |
| Structure-activity relationships: analogues of the dicaffeoylquinic and dicaffeoyltartaric acids as potent inhibitors of human immunodeficiency virus type 1 integrase and replication. | Journal of medicinal chemistry 19990211 |
| Resistance to the anti-human immunodeficiency virus type 1 compound L-chicoric acid results from a single mutation at amino acid 140 of integrase. | Journal of virology 19981001 |
| Human immunodeficiency virus type 1 cDNA integration: new aromatic hydroxylated inhibitors and studies of the inhibition mechanism. | Antimicrobial agents and chemotherapy 19980901 |
| L-chicoric acid, an inhibitor of human immunodeficiency virus type 1 (HIV-1) integrase, improves on the in vitro anti-HIV-1 effect of Zidovudine plus a protease inhibitor (AG1350). | Antiviral research 19980801 |
| Dicaffeoylquinic and dicaffeoyltartaric acids are selective inhibitors of human immunodeficiency virus type 1 integrase. | Antimicrobial agents and chemotherapy 19980101 |
| Dicaffeoylquinic acid inhibitors of human immunodeficiency virus integrase: inhibition of the core catalytic domain of human immunodeficiency virus integrase. | Molecular pharmacology 19961001 |
| Inhibitors of HIV-1 replication [corrected; erratum to be published] that inhibit HIV integrase. | Proceedings of the National Academy of Sciences of the United States of America 19960625 |