(3α,5β,7α)-3,7-Dihydroxycholan-24-oic acid
| Title | Journal |
|---|---|
| Alisol A 24-acetate ameliorates nonalcoholic steatohepatitis by inhibiting oxidative stress and stimulating autophagy through the AMPK/mTOR pathway. | Chemico-biological interactions 20180801 |
| Aryl hydrocarbon receptor (AhR) mediated short-term effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on bile acid homeostasis in mice. | Toxicology and applied pharmacology 20180315 |
| Activation of intestinal GR-FXR and PPARα-UGT signaling exacerbates ibuprofen-induced enteropathy in mice. | Archives of toxicology 20180301 |
| Pharmacotoxicology of clinically-relevant concentrations of obeticholic acid in an organotypic human hepatocyte system. | Toxicology in vitro : an international journal published in association with BIBRA 20170301 |
| Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor. | Toxicology letters 20170104 |
| Alisol B 23-acetate protects against non-alcoholic steatohepatitis in mice via farnesoid X receptor activation. | Acta pharmacologica Sinica 20170101 |
| Obeticholic acid protects against carbon tetrachloride-induced acute liver injury and inflammation. | Toxicology and applied pharmacology 20170101 |
| Differential modulation of FXR activity by chlorophacinone and ivermectin analogs. | Toxicology and applied pharmacology 20161215 |
| UDCA and CDCA alleviate 17α-ethinylestradiol-induced cholestasis through PKA-AMPK pathways in rats. | Toxicology and applied pharmacology 20161115 |
| Alterations in Enterohepatic Fgf15 Signaling and Changes in Bile Acid Composition Depend on Localization of Murine Intestinal Inflammation. | Inflammatory bowel diseases 20161001 |
| Obeticholic Acid: First Global Approval. | Drugs 20160801 |
| Chenodeoxycholic acid significantly impacts the expression of miRNAs and genes involved in lipid, bile acid and drug metabolism in human hepatocytes. | Life sciences 20160701 |
| Farnesoid X Receptor Protects against Kidney Injury in Uninephrectomized Obese Mice. | The Journal of biological chemistry 20160129 |
| Elevated copper impairs hepatic nuclear receptor function in Wilson's disease. | The Journal of clinical investigation 20150901 |
| The organic solute transporters alpha and beta are induced by hypoxia in human hepatocytes. | Liver international : official journal of the International Association for the Study of the Liver 20150401 |
| Individual bile acids have differential effects on bile acid signaling in mice. | Toxicology and applied pharmacology 20150215 |
| Urinary bile acids as biomarkers for liver diseases II. Signature profiles in patients. | Toxicological sciences : an official journal of the Society of Toxicology 20150201 |
| Farnesoid X receptor antagonizes JNK signaling pathway in liver carcinogenesis by activating SOD3. | Molecular endocrinology (Baltimore, Md.) 20150201 |
| Expression of drug transporters and drug metabolizing enzymes in the bladder urothelium in man and affinity of the bladder spasmolytic trospium chloride to transporters likely involved in its pharmacokinetics. | Molecular pharmaceutics 20150105 |
| Decreased bile-acid synthesis in livers of hepatocyte-conditional NADPH-cytochrome P450 reductase-null mice results in increased bile acids in serum. | The Journal of pharmacology and experimental therapeutics 20141001 |
| Potency of individual bile acids to regulate bile acid synthesis and transport genes in primary human hepatocyte cultures. | Toxicological sciences : an official journal of the Society of Toxicology 20141001 |
| 11β-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice. | Molecular metabolism 20140801 |
| Toxicity and intracellular accumulation of bile acids in sandwich-cultured rat hepatocytes: role of glycine conjugates. | Toxicology in vitro : an international journal published in association with BIBRA 20140301 |
| Suppression of autophagic flux by bile acids in hepatocytes. | Toxicological sciences : an official journal of the Society of Toxicology 20140201 |
| Quantitative high-throughput profiling of environmental chemicals and drugs that modulate farnesoid X receptor. | Scientific reports 20140101 |
| Aberrant activation of M phase proteins by cell proliferation-evoking carcinogens after 28-day administration in rats. | Toxicology letters 20130607 |
| Intrahepatic cholestasis of pregnancy levels of sulfated progesterone metabolites inhibit farnesoid X receptor resulting in a cholestatic phenotype. | Hepatology (Baltimore, Md.) 20130201 |
| An improved synthesis of 6α-ethylchenodeoxycholic acid (6ECDCA), a potent and selective agonist for the Farnesoid X Receptor (FXR). | Steroids 20121101 |
| Testosterone and farnesoid X receptor agonist INT-747 counteract high fat diet-induced bladder alterations in a rabbit model of metabolic syndrome. | The Journal of steroid biochemistry and molecular biology 20121001 |
| Specific bile acids inhibit hepatic fatty acid uptake in mice. | Hepatology (Baltimore, Md.) 20121001 |
| Involvement of multiple elements in FXR-mediated transcriptional activation of FGF19. | The Journal of steroid biochemistry and molecular biology 20121001 |
| BASIC--a bile acid-sensitive ion channel highly expressed in bile ducts. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20121001 |
| Formation of tubules by p-tert-butylphenylamide derivatives of chenodeoxycholic and ursodeoxycholic acids in aqueous solution. | Steroids 20121001 |
| In search of sustainable chemical processes: cloning, recombinant expression, and functional characterization of the 7α- and 7β-hydroxysteroid dehydrogenases from Clostridium absonum. | Applied microbiology and biotechnology 20120901 |
| Effect of probiotics on serum bile acids in patients with ulcerative colitis. | Hepato-gastroenterology 20120901 |
| Inhibition of butyrate uptake by the primary bile salt chenodeoxycholic acid in intestinal epithelial cells. | Journal of cellular biochemistry 20120901 |
| Kinetics of bile salt binding to liposomes revealed by carboxyfluorescein release and mathematical modeling. | Journal of liposome research 20120901 |
| Discovery and optimization of 1,3,4-trisubstituted-pyrazolone derivatives as novel, potent, and nonsteroidal farnesoid X receptor (FXR) selective antagonists. | Journal of medicinal chemistry 20120823 |
| Clinical reasoning: a case of treatable spastic paraparesis. | Neurology 20120807 |
| Simultaneous evaluation of six human glucuronidation activities in liver microsomes using liquid chromatography-tandem mass spectrometry. | Analytical biochemistry 20120801 |
| Determination of binding affinity for chenodeoxycholate in equilibrium with sulfobutylether-β-cyclodextrin. | Journal of pharmaceutical sciences 20120801 |
| Farnesoid X receptor regulates vascular reactivity through nitric oxide mechanism. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20120801 |
| Triterpenes from Alisma orientalis act as farnesoid X receptor agonists. | Bioorganic & medicinal chemistry letters 20120715 |
| Chenodeoxycholic acid through a TGR5-dependent CREB signaling activation enhances cyclin D1 expression and promotes human endometrial cancer cell proliferation. | Cell cycle (Georgetown, Tex.) 20120715 |
| In situ investigation of dye adsorption on TiO2 films using a quartz crystal microbalance with a dissipation technique. | Physical chemistry chemical physics : PCCP 20120707 |
| Putative irreversible inhibitors of the human sodium-dependent bile acid transporter (hASBT; SLC10A2) support the role of transmembrane domain 7 in substrate binding/translocation. | Pharmaceutical research 20120701 |
| Effect of ursodeoxycholic acid on bile acid profiles and intestinal detoxification machinery in primary biliary cirrhosis and health. | Journal of hepatology 20120701 |
| Glucocorticoid receptor mediates the gluconeogenic activity of the farnesoid X receptor in the fasting condition. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120701 |
| Investigation of imatinib and other approved drugs as starting points for antidiabetic drug discovery with FXR modulating activity. | Biochemical pharmacology 20120615 |
| Activation of farnesoid X receptor attenuates liver injury in systemic lupus erythematosus. | Rheumatology international 20120601 |
| Probiotics decreased the bioavailability of the bile acid analog, monoketocholic acid, when coadministered with gliclazide, in healthy but not diabetic rats. | European journal of drug metabolism and pharmacokinetics 20120601 |
| Molecular interactions between selected sodium salts of bile acids and morphine hydrochloride. | Colloids and surfaces. B, Biointerfaces 20120601 |
| Progressive familial intrahepatic cholestasis and inborn errors of bile acid synthesis. | Clinics and research in hepatology and gastroenterology 20120601 |
| [Progress in the ligands and their complex structures of farnesoid X receptor]. | Yao xue xue bao = Acta pharmaceutica Sinica 20120601 |
| The effect of physiological concentrations of bile acids on in vitro growth of Mycobacterium tuberculosis. | South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20120523 |
| Molecular dynamics simulations on the aggregation behavior of indole type organic dye molecules in dye-sensitized solar cells. | Journal of molecular modeling 20120501 |
| Cytochrome P450s in the synthesis of cholesterol and bile acids--from mouse models to human diseases. | The FEBS journal 20120501 |
| Discovery and structural development of small molecules that enhance transport activity of bile salt export pump mutant associated with progressive familial intrahepatic cholestasis type 2. | Bioorganic & medicinal chemistry 20120501 |
| Nelumal A, the active principle from Ligularia nelumbifolia, is a novel farnesoid X receptor agonist. | Bioorganic & medicinal chemistry letters 20120501 |
| The Sigma class glutathione transferase from the liver fluke Fasciola hepatica. | PLoS neglected tropical diseases 20120501 |
| Biophysical investigations into the interactions of endotoxins with bile acids. | Innate immunity 20120401 |
| Cerebrotendinous xanthomatosis revealed in drug-resistant epilepsy diagnostic workup. | The American journal of the medical sciences 20120401 |
| Unusual binding of ursodeoxycholic acid to ileal bile acid binding protein: role in activation of FXRα. | Journal of lipid research 20120401 |
| Sesquiterpenoids from Atractylodes macrocephala act as farnesoid X receptor and progesterone receptor modulators. | Bioorganic & medicinal chemistry letters 20120315 |
| High-performance organic materials for dye-sensitized solar cells: triarylene-linked dyads with a 4-tert-butylphenylamine donor. | Chemistry, an Asian journal 20120305 |
| Comparative studies on animal models for Opisthorchis viverrini infection: host interaction through susceptibility and pathology. | Parasitology research 20120301 |
| Gender, but not CYP7A1 or SLCO1B1 polymorphism, affects the fasting plasma concentrations of bile acids in human beings. | Basic & clinical pharmacology & toxicology 20120301 |
| Multiple functions of a multi-component mating pheromone in sea lamprey Petromyzon marinus. | Journal of fish biology 20120301 |
| Mitochondrial oxidative stress alters a pathway in Caenorhabditis elegans strongly resembling that of bile acid biosynthesis and secretion in vertebrates. | PLoS genetics 20120301 |
| In vitro and in silico strategies to identify OATP1B1 inhibitors and predict clinical drug-drug interactions. | Pharmaceutical research 20120201 |
| A tea catechin, epigallocatechin-3-gallate, is a unique modulator of the farnesoid X receptor. | Toxicology and applied pharmacology 20120115 |
| Conicasterol E, a small heterodimer partner sparing farnesoid X receptor modulator endowed with a pregnane X receptor agonistic activity, from the marine sponge Theonella swinhoei. | Journal of medicinal chemistry 20120112 |
| The bile steroid chenodeoxycholate is a potent antagonist at NMDA and GABA(A) receptors. | Neuroscience letters 20120111 |
| A biliary HCO3- umbrella constitutes a protective mechanism against bile acid-induced injury in human cholangiocytes. | Hepatology (Baltimore, Md.) 20120101 |
| Three siblings with Cerebrotendinous Xanthomatosis: a novel mutation in the CYP27A1 gene. | European journal of medical genetics 20120101 |
| Bile Acid signaling in liver metabolism and diseases. | Journal of lipids 20120101 |
| Testosterone protects from metabolic syndrome-associated prostate inflammation: an experimental study in rabbit. | The Journal of endocrinology 20120101 |
| Identification and characterization of two bile acid coenzyme A transferases from Clostridium scindens, a bile acid 7α-dehydroxylating intestinal bacterium. | Journal of lipid research 20120101 |
| Eicosapentaenoic acid and docosahexaenoic acid synergistically attenuate bile acid-induced hepatocellular apoptosis. | JPEN. Journal of parenteral and enteral nutrition 20120101 |
| Mechanistic studies of the effect of bile salts on rhodamine 123 uptake into RBE4 cells. | Molecular pharmaceutics 20120101 |
| Waterborne manganese exposure alters plasma, brain, and liver metabolites accompanied by changes in stereotypic behaviors. | Neurotoxicology and teratology 20120101 |
| Enteral bile acid treatment improves parenteral nutrition-related liver disease and intestinal mucosal atrophy in neonatal pigs. | American journal of physiology. Gastrointestinal and liver physiology 20120101 |
| FXR protects lung from lipopolysaccharide-induced acute injury. | Molecular endocrinology (Baltimore, Md.) 20120101 |
| Magnesium chenoursodeoxycholic acid ameliorates carbon tetrachloride-induced liver fibrosis in rats. | Experimental biology and medicine (Maywood, N.J.) 20120101 |
| Nuclear receptors in nonalcoholic Fatty liver disease. | Journal of lipids 20120101 |
| Non-alcoholic Fatty liver disease: the bile Acid-activated farnesoid x receptor as an emerging treatment target. | Journal of lipids 20120101 |
| Rifampicin Does not Significantly Affect the Expression of Small Heterodimer Partner in Primary Human Hepatocytes. | Frontiers in pharmacology 20120101 |
| Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis. | PloS one 20120101 |
| Spores of Clostridium difficile clinical isolates display a diverse germination response to bile salts. | PloS one 20120101 |
| Fetal outcomes in pregnancies complicated by intrahepatic cholestasis of pregnancy in a Northern California cohort. | PloS one 20120101 |
| Gender-divergent profile of bile acid homeostasis during aging of mice. | PloS one 20120101 |
| Oral gallstone dissolution therapies. | Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses 20120101 |
| Dysfunction of organic anion transporting polypeptide 1a1 alters intestinal bacteria and bile acid metabolism in mice. | PloS one 20120101 |
| Effects of human and porcine bile on the proteome of Helicobacter hepaticus. | Proteome science 20120101 |
| Farnesoid X receptor induces murine scavenger receptor Class B type I via intron binding. | PloS one 20120101 |
| Medical therapy of acromegaly. | International journal of endocrinology 20120101 |
| Bile acids specifically increase hepatitis C virus RNA-replication. | PloS one 20120101 |
| A pleiotropic role for the orphan nuclear receptor small heterodimer partner in lipid homeostasis and metabolic pathways. | Journal of lipids 20120101 |
| Cholesterol-lowering probiotics as potential biotherapeutics for metabolic diseases. | Experimental diabetes research 20120101 |
| Effect of ursodeoxycholic Acid alone and ursodeoxycholic Acid plus domperidone on radiolucent gallstones and gallbladder contractility in humans. | Gastroenterology research and practice 20120101 |
| Epigenetics modifications and therapeutic prospects in human thyroid cancer. | Frontiers in endocrinology 20120101 |
| The evolving landscape of neurotoxicity by unconjugated bilirubin: role of glial cells and inflammation. | Frontiers in pharmacology 20120101 |
| Inhibition of intestinal bile acid transporter Slc10a2 improves triglyceride metabolism and normalizes elevated plasma glucose levels in mice. | PloS one 20120101 |
| Alterations in the detergent-induced membrane permeability and solubilization of saturated phosphatidylcholine/cholesterol liposomes: effects of poly(ethylene glycol)-conjugated lipid. | Chemical & pharmaceutical bulletin 20120101 |
| Cerebrotendinous xanthomatosis: a rare disorder with a rare presentation. | BMJ case reports 20120101 |
| Metabolic profiling reveals sphingosine-1-phosphate kinase 2 and lyase as key targets of (phyto-) estrogen action in the breast cancer cell line MCF-7 and not in MCF-12A. | PloS one 20120101 |
| Improvement of low bioavailability of a novel factor Xa inhibitor through formulation of cationic additives in its oral dosage form. | International journal of pharmaceutics 20111215 |
| Activation of the farnesoid-X receptor protects against gastrointestinal injury caused by non-steroidal anti-inflammatory drugs in mice. | British journal of pharmacology 20111201 |
| Role of farnesoid X receptor (FXR) in the process of differentiation of bone marrow stromal cells into osteoblasts. | Bone 20111201 |
| Targeting bile acids in the treatment of constipation. | Expert review of gastroenterology & hepatology 20111201 |
| Pharmacophore-based discovery of FXR agonists. Part I: Model development and experimental validation. | Bioorganic & medicinal chemistry 20111201 |
| Searching for the main anti-bacterial components in artificial Calculus bovis using UPLC and microcalorimetry coupled with multi-linear regression analysis. | Journal of separation science 20111201 |
| Effect of twice-daily oral administration of hydrocortisone on the bile acids composition of gallbladder bile in dogs. | American journal of veterinary research 20111201 |
| Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
| Natural products from the Lithistida: a review of the literature since 2000. | Marine drugs 20111201 |
| Pharmacophore-based discovery of FXR-agonists. Part II: identification of bioactive triterpenes from Ganoderma lucidum. | Bioorganic & medicinal chemistry 20111115 |
| The role of the acquisition methods in the analysis of natural and synthetic steroids and cholic acids by gas chromatography-mass spectrometry. | Journal of chromatography. A 20111111 |
| Scoparone potentiates transactivation of the bile salt export pump gene and this effect is enhanced by cytochrome P450 metabolism but abolished by a PKC inhibitor. | British journal of pharmacology 20111101 |
| Critical illness evokes elevated circulating bile acids related to altered hepatic transporter and nuclear receptor expression. | Hepatology (Baltimore, Md.) 20111101 |
| Bile acids promote HCV replication through the EGFR/ERK pathway in replicon-harboring cells. | Intervirology 20111001 |
| A randomized placebo-controlled phase IIb trial of a3309, a bile acid transporter inhibitor, for chronic idiopathic constipation. | The American journal of gastroenterology 20111001 |
| Cerebrotendinous xanthomatosis in Spain: clinical, prognostic, and genetic survey. | European journal of neurology 20111001 |
| Dose-response of five bile acids on serum and liver bile Acid concentrations and hepatotoxicty in mice. | Toxicological sciences : an official journal of the Society of Toxicology 20111001 |
| Deoxycholic and chenodeoxycholic bile acids induce apoptosis via oxidative stress in human colon adenocarcinoma cells. | Apoptosis : an international journal on programmed cell death 20111001 |
| Primary bile acid therapy during pregnancy in patients with 3β-hydroxy-Δ5 -C27 -steroid oxidoreductase deficiency. | Pediatrics international : official journal of the Japan Pediatric Society 20111001 |
| Farnesoid X receptor inhibits tamoxifen-resistant MCF-7 breast cancer cell growth through downregulation of HER2 expression. | Oncogene 20110929 |
| [Usefulness of cholestanol levels in the diagnosis and follow-up of patients with cerebrotendinous xanthomatosis]. | Neurologia (Barcelona, Spain) 20110901 |
| High-dose ursodeoxycholic acid is associated with the development of colorectal neoplasia in patients with ulcerative colitis and primary sclerosing cholangitis. | The American journal of gastroenterology 20110901 |
| Monitoring of 7α-hydroxy-4-cholesten-3-one during therapy of cerebrotendinous xanthomatosis: a case report. | Chemistry and physics of lipids 20110901 |
| Pharmacologic and complementary and alternative medicine therapies for irritable bowel syndrome. | Gut and liver 20110901 |
| Insulin resistance as a risk factor for gallbladder stone formation in Korean postmenopausal women. | The Korean journal of internal medicine 20110901 |
| The diagnosis and treatment of primary biliary cirrhosis. | The Korean journal of hepatology 20110901 |
| β-Cyclodextrin dimers linked through their secondary faces with rigid spacer arms as hosts for bile salts. | Langmuir : the ACS journal of surfaces and colloids 20110816 |
| Carcinogenicity of deoxycholate, a secondary bile acid. | Archives of toxicology 20110801 |
| Farnesoid X receptor activation by chenodeoxycholic acid induces detoxifying enzymes through AMP-activated protein kinase and extracellular signal-regulated kinase 1/2-mediated phosphorylation of CCAAT/enhancer binding protein β. | Drug metabolism and disposition: the biological fate of chemicals 20110801 |
| Farnesoid X receptor agonist for the treatment of liver and metabolic disorders: focus on 6-ethyl-CDCA. | Mini reviews in medicinal chemistry 20110801 |
| Cerebrotendinous xanthomatosis: a treatable disease with juvenile cataracts as a presenting sign. | Archives of ophthalmology (Chicago, Ill. : 1960) 20110801 |
| Metabolomic investigation of cholestasis in a rat model using ultra-performance liquid chromatography/tandem mass spectrometry. | Rapid communications in mass spectrometry : RCM 20110715 |
| Serum and urine metabolite profiling reveals potential biomarkers of human hepatocellular carcinoma. | Molecular & cellular proteomics : MCP 20110701 |
| Ruminal methane inhibition potential of various pure compounds in comparison with garlic oil as determined with a rumen simulation technique (Rusitec). | The British journal of nutrition 20110701 |
| Hepatic reduction of the secondary bile acid 7-oxolithocholic acid is mediated by 11β-hydroxysteroid dehydrogenase 1. | The Biochemical journal 20110615 |
| Chenodeoxycholic acid stabilization of LDL receptor mRNA depends on 3'-untranslated region and AU-rich element-binding protein. | Biochemical and biophysical research communications 20110603 |
| Visualisation of treatment response in a case of cerebrotendinous xanthomatosis. | Journal of neurology, neurosurgery, and psychiatry 20110601 |
| SHP-dependent and -independent induction of peroxisome proliferator-activated receptor-γ by the bile acid sensor farnesoid X receptor counter-regulates the pro-inflammatory phenotype of liver myofibroblasts. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20110601 |
| Suppression of cytochrome P450 reductase (POR) expression in hepatoma cells replicates the hepatic lipidosis observed in hepatic POR-null mice. | Drug metabolism and disposition: the biological fate of chemicals 20110601 |
| Clinical relevance and neurophysiological correlates of spasticity in cerebrotendinous xanthomatosis. | Journal of neurology 20110501 |
| Effects of intervention with sulindac and inulin/VSL#3 on mucosal and luminal factors in the pouch of patients with familial adenomatous polyposis. | International journal of colorectal disease 20110501 |
| Farnesoid X receptor agonists for primary biliary cirrhosis. | Current opinion in gastroenterology 20110501 |
| Histone H3K4 trimethylation by MLL3 as part of ASCOM complex is critical for NR activation of bile acid transporter genes and is downregulated in cholestasis. | American journal of physiology. Gastrointestinal and liver physiology 20110501 |
| Protective effects of Mg-CUD against D-galactosamine-induced hepatotoxicity in rats. | European journal of pharmacology 20110425 |
| Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease. | Gut 20110401 |
| Substrate specificity and inhibitor analyses of human steroid 5β-reductase (AKR1D1). | Steroids 20110401 |
| Differential disposition of chenodeoxycholic acid versus taurocholic acid in response to acute troglitazone exposure in rat hepatocytes. | Toxicological sciences : an official journal of the Society of Toxicology 20110401 |
| Helicobacter hepaticus--induced liver tumor promotion is associated with increased serum bile acid and a persistent microbial-induced immune response. | Cancer research 20110401 |
| Low levels of bile acids increase bacterial uptake in colonic biopsies from patients with collagenous colitis in remission. | Alimentary pharmacology & therapeutics 20110401 |
| Discovery of sulfated sterols from marine invertebrates as a new class of marine natural antagonists of farnesoid-X-receptor. | Journal of medicinal chemistry 20110310 |
| Synthesis and in vitro evaluation of gabapentin prodrugs that target the human apical sodium-dependent bile acid transporter (hASBT). | Journal of pharmaceutical sciences 20110301 |
| Engineered three-dimensional liver mimics recapitulate critical rat-specific bile acid pathways. | Tissue engineering. Part A 20110301 |
| Pathophysiological relevance of apical large-conductance Ca²+-activated potassium channels in pancreatic duct epithelial cells. | Gut 20110301 |
| Farnesoid X receptor suppresses constitutive androstane receptor activity at the multidrug resistance protein-4 promoter. | Biochimica et biophysica acta 20110301 |
| Overexpression of cholesterol 7α-hydroxylase promotes hepatic bile acid synthesis and secretion and maintains cholesterol homeostasis. | Hepatology (Baltimore, Md.) 20110301 |
| Mitochondrial disorders in NSAIDs-induced small bowel injury. | Journal of clinical biochemistry and nutrition 20110301 |
| The role of lithocholic acid in the regulation of bile acid detoxication, synthesis, and transport proteins in rat and human intestine and liver slices. | Toxicology in vitro : an international journal published in association with BIBRA 20110201 |
| Response of cricopharyngeus muscle to esophageal stimulation by mechanical distension and acid and bile perfusion. | The Annals of otology, rhinology, and laryngology 20110201 |
| Determination of bile acids in pig liver, pig kidney and bovine liver by gas chromatography-chemical ionization tandem mass spectrometry with total ion chromatograms and extraction ion chromatograms. | Journal of chromatography. A 20110121 |
| Gas chromatography-mass spectrometry-based simultaneous quantitative analytical method for urinary oxysterols and bile acids in rats. | Analytical biochemistry 20110115 |
| Screening for novel antibacterial agents based on the activities of compounds on metabolism of Escherichia coli: a microcalorimetric study. | Journal of hazardous materials 20110115 |
| Differentiation of various traditional Chinese medicines derived from animal bile and gallstone: simultaneous determination of bile acids by liquid chromatography coupled with triple quadrupole mass spectrometry. | Journal of chromatography. A 20110107 |
| Effects of farnesoid X receptor on the expression of the fatty acid synthetase and hepatic lipase. | Molecular biology reports 20110101 |
| Non-conjugated chenodeoxycholate induces severe mitochondrial damage and inhibits bicarbonate transport in pancreatic duct cells. | Gut 20110101 |
| The crystal structures of the Salmonella type III secretion system tip protein SipD in complex with deoxycholate and chenodeoxycholate. | Protein science : a publication of the Protein Society 20110101 |
| The relationship between postprandial bile acid concentration, GLP-1, PYY and ghrelin. | Clinical endocrinology 20110101 |
| SPECT imaging for brain improvement quantification in a patient with cerebrotendinous xanthomatosis. | Clinical nuclear medicine 20110101 |
| Bile acids induce inflammatory genes in hepatocytes: a novel mechanism of inflammation during obstructive cholestasis. | The American journal of pathology 20110101 |
| Discovering networks of perturbed biological processes in hepatocyte cultures. | PloS one 20110101 |
| Inflammatory pseudo-tumor of the liver: a rare pathological entity. | World journal of surgical oncology 20110101 |
| Metabolomic profiling for identification of novel potential biomarkers in cardiovascular diseases. | Journal of biomedicine & biotechnology 20110101 |
| The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species. | BMC biochemistry 20110101 |
| Ethidium bromide transport across Mycobacterium smegmatis cell-wall: correlation with antibiotic resistance. | BMC microbiology 20110101 |
| Diurnal variations of mouse plasma and hepatic bile acid concentrations as well as expression of biosynthetic enzymes and transporters. | PloS one 20110101 |
| Mechanisms of oxysterol-induced carcinogenesis. | Lipids in health and disease 20110101 |
| Sex differences in drug disposition. | Journal of biomedicine & biotechnology 20110101 |
| FGF19 regulates cell proliferation, glucose and bile acid metabolism via FGFR4-dependent and independent pathways. | PloS one 20110101 |
| Cattle bile aggravates diclofenac sodium-induced small intestinal injury in mice. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
| Neuromuscular abnormality and autonomic dysfunction in patients with cerebrotendinous xanthomatosis. | BMC neurology 20110101 |
| Herbert Falk: a vital force in the renaissance of bile acid research and bile acid therapy. | Digestive diseases (Basel, Switzerland) 20110101 |
| Biliary bicarbonate secretion constitutes a protective mechanism against bile acid-induced injury in man. | Digestive diseases (Basel, Switzerland) 20110101 |
| Genetic variants of the bile salt export pump: inducers and modifiers of liver diseases. | Digestive diseases (Basel, Switzerland) 20110101 |
| Statistical methods for assays with limits of detection: Serum bile acid as a differentiator between patients with normal colons, adenomas, and colorectal cancer. | Journal of carcinogenesis 20110101 |
| Fasting plasma chenodeoxycholic acid and cholic acid concentrations are inversely correlated with insulin sensitivity in adults. | Nutrition & metabolism 20110101 |
| TGR5: a novel target for weight maintenance and glucose metabolism. | Experimental diabetes research 20110101 |
| Profiling circulating and urinary bile acids in patients with biliary obstruction before and after biliary stenting. | PloS one 20110101 |
| Pancreatic ductal bicarbonate secretion: challenge of the acinar Acid load. | Frontiers in physiology 20110101 |
| Transformation of chenodeoxycholic acid by thermophilic Geobacillus stearothermophilus. | Biotechnology and applied biochemistry 20110101 |
| Impact of bile acids on the growth of human cholangiocarcinoma via FXR. | Journal of hematology & oncology 20110101 |
| 2 Novel deletions of the sterol 27-hydroxylase gene in a Chinese Family with Cerebrotendinous Xanthomatosis. | BMC neurology 20110101 |
| Enteric microbiome metabolites correlate with response to simvastatin treatment. | PloS one 20110101 |
| Mychonastes afer HSO-3-1 as a potential new source of biodiesel. | Biotechnology for biofuels 20110101 |
| The bile acid receptor GPBAR-1 (TGR5) modulates integrity of intestinal barrier and immune response to experimental colitis. | PloS one 20110101 |
| Bile acid metabolites in serum: intraindividual variation and associations with coronary heart disease, metabolic syndrome and diabetes mellitus. | PloS one 20110101 |
| Astragalus polysaccharides lowers plasma cholesterol through mechanisms distinct from statins. | PloS one 20110101 |
| Active transport of bile acids decreases mucin 2 in neonatal ileum: implications for development of necrotizing enterocolitis. | PloS one 20110101 |
| Cerebrotendinous xanthomatosis: a rare cause of spinocerebellar syndrome. | Neurologia i neurochirurgia polska 20110101 |
| Structural determinants for transport across the intestinal bile acid transporter using C-24 bile acid conjugates. | Molecular pharmaceutics 20101206 |
| A predictive ligand-based Bayesian model for human drug-induced liver injury. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
| Protective effect of bile acids on the onset of fructose-induced hepatic steatosis in mice. | Journal of lipid research 20101201 |
| Endocrine, metabolic, nutritional, and toxic disorders leading to dementia. | Annals of Indian Academy of Neurology 20101201 |
| Structural requirements of the ASBT by 3D-QSAR analysis using aminopyridine conjugates of chenodeoxycholic acid. | Bioconjugate chemistry 20101117 |
| Application of near infrared spectroscopy for rapid analysis of intermediates of Tanreqing injection. | Journal of pharmaceutical and biomedical analysis 20101102 |
| Effects of feeding bile acids and a bile acid sequestrant on hepatic bile acid composition in mice. | Journal of lipid research 20101101 |
| Chenodeoxycholate in females with irritable bowel syndrome-constipation: a pharmacodynamic and pharmacogenetic analysis. | Gastroenterology 20101101 |
| The influence of NaCl on hydrophobicity of selected, pharmacologically active bile acids expressed with chromatographic retention index and critical micellar concentration. | Colloids and surfaces. B, Biointerfaces 20101101 |
| Inflammatory mediators of esophagitis alter p27 Kip1 expression in esophageal epithelial cells. | Journal of pediatric gastroenterology and nutrition 20101101 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| Analysis of serum bile acids by isotope dilution-mass spectrometry to assess the performance of routine total bile acid methods. | Annals of clinical biochemistry 20101101 |
| Cerebrotendinous xanthomatosis: a treatable hereditary neuro-metabolic disease. | Clinics (Sao Paulo, Brazil) 20101101 |
| A microfluidic approach for in vitro assessment of interorgan interactions in drug metabolism using intestinal and liver slices. | Lab on a chip 20101021 |
| Quantification of the 15 major human bile acids and their precursor 7α-hydroxy-4-cholesten-3-one in serum by liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015 |
| Steroid degradation genes in Comamonas testosteroni TA441: Isolation of genes encoding a Δ4(5)-isomerase and 3α- and 3β-dehydrogenases and evidence for a 100 kb steroid degradation gene hot spot. | The Journal of steroid biochemistry and molecular biology 20101001 |
| Inhibiting the initiation of Clostridium difficile spore germination using analogs of chenodeoxycholic acid, a bile acid. | Journal of bacteriology 20101001 |
| Improved glycemic control with colesevelam treatment in patients with type 2 diabetes is not directly associated with changes in bile acid metabolism. | Hepatology (Baltimore, Md.) 20101001 |
| Modelling phase transition kinetics of chenodeoxycholic acid with the Runge-Kutta method. | Journal of pharmaceutical and biomedical analysis 20100921 |
| Simple and practical derivatization procedure for enhanced detection of carboxylic acids in liquid chromatography-electrospray ionization-tandem mass spectrometry. | Journal of pharmaceutical and biomedical analysis 20100905 |
| Molecular genetic and bile acid profiles in two Japanese patients with 3beta-hydroxy-DELTA5-C27-steroid dehydrogenase/isomerase deficiency. | Pediatric research 20100901 |
| Two time-point assessment of bile acid kinetics in humans using stable isotopes. | Isotopes in environmental and health studies 20100901 |
| Construction of confidence regions for isotopic abundance patterns in LC/MS data sets for rigorous determination of molecular formulas. | Analytical chemistry 20100901 |
| [Chemical constituents of bear bile]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100901 |
| Synthesis and in vitro evaluation of potential sustained release prodrugs via targeting ASBT. | International journal of pharmaceutics 20100830 |
| Bile acids regulate hepatic gluconeogenic genes and farnesoid X receptor via G(alpha)i-protein-coupled receptors and the AKT pathway. | Journal of lipid research 20100801 |
| Retinoic acid represses CYP7A1 expression in human hepatocytes and HepG2 cells by FXR/RXR-dependent and independent mechanisms. | Journal of lipid research 20100801 |
| A putative role of micro RNA in regulation of cholesterol 7alpha-hydroxylase expression in human hepatocytes. | Journal of lipid research 20100801 |
| 3β-hydroxy-Δ⁵-C₂₇-steroid dehydrogenase/isomerase deficiency in a patient who underwent oral bile acid therapy for 10 years and delivered two healthy infants. | Pediatrics international : official journal of the Japan Pediatric Society 20100801 |
| Effects of DCA on Cell Cycle Proteins in Colonocytes. | Journal of the Korean Society of Coloproctology 20100801 |
| Synthesis of bile acid derivatives and in vitro cytotoxic activity with pro-apoptotic process on multiple myeloma (KMS-11), glioblastoma multiforme (GBM), and colonic carcinoma (HCT-116) human cell lines. | European journal of medicinal chemistry 20100701 |
| Two farnesoid X receptor alpha isoforms in Japanese medaka (Oryzias latipes) are differentially activated in vitro. | Aquatic toxicology (Amsterdam, Netherlands) 20100701 |
| Bile acid changes after high-dose ursodeoxycholic acid treatment in primary sclerosing cholangitis: Relation to disease progression. | Hepatology (Baltimore, Md.) 20100701 |
| Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes. | Aging 20100701 |
| Farnesoid X receptor activation prevents the development of vascular calcification in ApoE-/- mice with chronic kidney disease. | Circulation research 20100625 |
| [Effects of bile acids on expression of interleukin-6 and cell viability in QBC939 cell line]. | Zhonghua wai ke za zhi [Chinese journal of surgery] 20100615 |
| Determination of multicomponent contents in Calculus bovis by ultra-performance liquid chromatography-evaporative light scattering detection and its application for quality control. | Journal of separation science 20100601 |
| Hydrophobicity and haemolytic potential of oxo derivatives of cholic, deoxycholic and chenodeoxycholic acids. | Steroids 20100601 |
| Bile acids: short and long term effects in the intestine. | Scandinavian journal of gastroenterology 20100601 |
| Titration of bile acid supplements in 3beta-hydroxy-Delta 5-C27-steroid dehydrogenase/isomerase deficiency. | Journal of pediatric gastroenterology and nutrition 20100601 |
| Neuropathy, retinopathy, and glucose-lowering treatments. | Diabetes care 20100601 |
| Characterization of porcine pregnane X receptor, farnesoid X receptor and their splice variants. | Experimental biology and medicine (Maywood, N.J.) 20100601 |
| Pharmacotherapy of cholestatic liver diseases. | Journal of digestive diseases 20100601 |
| NMR characterization of the interaction of the Salmonella type III secretion system protein SipD and bile salts. | Biochemistry 20100518 |
| Regulation of bile acid synthesis by fat-soluble vitamins A and D. | The Journal of biological chemistry 20100507 |
| Bile acids modulate glucocorticoid metabolism and the hypothalamic-pituitary-adrenal axis in obstructive jaundice. | Journal of hepatology 20100501 |
| Metabonomics study of urine and plasma in depression and excess fatigue rats by ultra fast liquid chromatography coupled with ion trap-time of flight mass spectrometry. | Molecular bioSystems 20100501 |
| Isolation and characterization of a bile acid inducible 7alpha-dehydroxylating operon in Clostridium hylemonae TN271. | Anaerobe 20100401 |
| Ursodeoxycholic acid switches oxaliplatin-induced necrosis to apoptosis by inhibiting reactive oxygen species production and activating p53-caspase 8 pathway in HepG2 hepatocellular carcinoma. | International journal of cancer 20100401 |
| FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats. | Journal of lipid research 20100401 |
| Bile acid-activated receptors in the treatment of dyslipidemia and related disorders. | Progress in lipid research 20100401 |
| Regulation of VDR expression in rat and human intestine and liver--consequences for CYP3A expression. | Toxicology in vitro : an international journal published in association with BIBRA 20100401 |
| alpha(1)-fetoprotein transcription factor (FTF)/liver receptor homolog-1 (LRH-1) is an essential lipogenic regulator. | Biochimica et biophysica acta 20100401 |
| Salivary chenodeoxycholic acid and its glycine-conjugate: their determination method using LC-MS/MS and variation of their concentrations with increased saliva flow rate. | Steroids 20100401 |
| Regulation of the human bile acid UDP-glucuronosyltransferase 1A3 by the farnesoid X receptor and bile acids. | Journal of hepatology 20100401 |
| Cerebrotendinous xanthomatosis presenting with severe externalized disorder: improvement after one year of treatment with chenodeoxycholic Acid. | CNS spectrums 20100401 |
| Identification of farnesoid X receptor modulators by a fluorescence polarization-based interaction assay. | Analytical biochemistry 20100315 |
| Oleanolic acid is a selective farnesoid X receptor modulator. | Phytotherapy research : PTR 20100301 |
| Impacts of different promoters on the mammalian one-hybrid assay for detecting nuclear receptor agonists. | Analytical and bioanalytical chemistry 20100301 |
| Kinetic analysis of bile acid sulfation by stably expressed human sulfotransferase 2A1 (SULT2A1). | Xenobiotica; the fate of foreign compounds in biological systems 20100301 |
| Past, present and future therapeutics for cerebellar ataxias. | Current neuropharmacology 20100301 |
| Farnesoid X receptor, through the binding with steroidogenic factor 1-responsive element, inhibits aromatase expression in tumor Leydig cells. | The Journal of biological chemistry 20100219 |
| Upregulation of early growth response factor-1 by bile acids requires mitogen-activated protein kinase signaling. | Toxicology and applied pharmacology 20100215 |
| Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain? | The Journal of biological chemistry 20100212 |
| Effects of chenodeoxycholate and a bile acid sequestrant, colesevelam, on intestinal transit and bowel function. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20100201 |
| Regulation of diurnal variation of cholesterol 7alpha-hydroxylase (CYP7A1) activity in healthy subjects. | Physiological research 20100101 |
| Variable clinical spectrum of the most common inborn error of bile acid metabolism--3beta-hydroxy-Delta 5-C27-steroid dehydrogenase deficiency. | Journal of pediatric gastroenterology and nutrition 20100101 |
| High performance liquid chromatography-tandem mass spectrometry for the determination of bile acid concentrations in human plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100101 |
| Plasma bile acid concentrations in patients with human immunodeficiency virus infection receiving protease inhibitor therapy: possible implications for hepatotoxicity. | Pharmacotherapy 20100101 |
| Effect of prototypical inducers on ligand activated nuclear receptor regulated drug disposition genes in rodent hepatic and intestinal cells. | Acta pharmacologica Sinica 20100101 |
| Metabolism of bile salts in mice influences spore germination in Clostridium difficile. | PloS one 20100101 |
| Bile acids induce cdx2 expression through the farnesoid x receptor in gastric epithelial cells. | Journal of clinical biochemistry and nutrition 20100101 |
| Reduced levels of hydroxylated, polyunsaturated ultra long-chain fatty acids in the serum of colorectal cancer patients: implications for early screening and detection. | BMC medicine 20100101 |
| Evolutionary diversity of bile salts in reptiles and mammals, including analysis of ancient human and extinct giant ground sloth coprolites. | BMC evolutionary biology 20100101 |
| Identification of novel pathogenicity loci in Clostridium perfringens strains that cause avian necrotic enteritis. | PloS one 20100101 |
| Fenofibrate in primary biliary cirrhosis: a pilot study. | The open cardiovascular medicine journal 20100101 |
| Multi-parametric neuroimaging evaluation of cerebrotendinous xanthomatosis and its correlation with neuropsychological presentations. | BMC neurology 20100101 |
| Transport of estrone 3-sulfate mediated by organic anion transporter OATP4C1: estrone 3-sulfate binds to the different recognition site for digoxin in OATP4C1. | Drug metabolism and pharmacokinetics 20100101 |
| Metabolic bone disease in lion cubs at the London Zoo in 1889: the original animal model of rickets. | Journal of biomedical science 20100101 |
| Plasma bile acids are not associated with energy metabolism in humans. | Nutrition & metabolism 20100101 |
| Analyzing the regulation of metabolic pathways in human breast cancer. | BMC medical genomics 20100101 |
| The Role of PPARα Activation in Liver and Muscle. | PPAR research 20100101 |
| A novel mutation in the sterol 27-hydroxylase gene of a woman with autosomal recessive cerebrotendinous xanthomatosis. | Orphanet journal of rare diseases 20100101 |
| The bile acid sensor FXR protects against dyslipidemia and aortic plaques development induced by the HIV protease inhibitor ritonavir in mice. | PloS one 20100101 |
| Bile acid-induced virulence gene expression of Vibrio parahaemolyticus reveals a novel therapeutic potential for bile acid sequestrants. | PloS one 20100101 |
| Liver X receptor agonist methyl-3β-hydroxy-5α,6α-epoxycholanate attenuates atherosclerosis in apolipoprotein E knockout mice without increasing plasma triglyceride. | Pharmacology 20100101 |
| Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting. | PloS one 20100101 |
| Antimicrobial peptides in gastrointestinal inflammation. | International journal of inflammation 20100101 |
| A novel statistical algorithm for gene expression analysis helps differentiate pregnane X receptor-dependent and independent mechanisms of toxicity. | PloS one 20100101 |
| Deciphering the nuclear bile acid receptor FXR paradigm. | Nuclear receptor signaling 20100101 |
| Microbial induction of immunity, inflammation, and cancer. | Frontiers in physiology 20100101 |
| Cerebrotendinous xanthomatosis associated with immune thrombocytopenia. | BMJ case reports 20100101 |
| Discovery of 6alpha-ethyl-23(S)-methylcholic acid (S-EMCA, INT-777) as a potent and selective agonist for the TGR5 receptor, a novel target for diabesity. | Journal of medicinal chemistry 20091224 |
| The farnesoid X receptor modulates renal lipid metabolism and diet-induced renal inflammation, fibrosis, and proteinuria. | American journal of physiology. Renal physiology 20091201 |
| Detection of Helicobacter hepaticus in human bile samples of patients with biliary disease. | Helicobacter 20091201 |
| Developments in bile acid kinetic measurements using (13)C and (2)H: 10(5) times improved sensitivity during the last 40 years. | Isotopes in environmental and health studies 20091201 |
| Determination of critical micellar concentrations of two monoketo derivatives of cholic acid. | Colloids and surfaces. B, Biointerfaces 20091101 |
| Effect of mitiglinide on Streptozotocin-induced experimental type 2 diabetic rats: a urinary metabonomics study based on ultra-performance liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091101 |
| CFTR expression but not Cl- transport is involved in the stimulatory effect of bile acids on apical Cl-/HCO3- exchange activity in human pancreatic duct cells. | Pancreas 20091101 |
| Bile acids and metabolic regulation: mechanisms and clinical responses to bile acid sequestration. | Diabetes care 20091101 |
| Case Report: Cerebrotendinous xanthomatosis. | The Indian journal of radiology & imaging 20091101 |
| Hepatocyte nuclear factor 1alpha plays a critical role in PCSK9 gene transcription and regulation by the natural hypocholesterolemic compound berberine. | The Journal of biological chemistry 20091016 |
| Modulation of bile acid metabolism by 1alpha-hydroxyvitamin D3 administration in mice. | Drug metabolism and disposition: the biological fate of chemicals 20091001 |
| Albumin dialysis molecular adsorbents recirculating system: impact of dialysate albumin concentration on detoxification efficacy. | Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20091001 |
| Cerebrotendinous xanthomatosis: a treatable neurodegenerative disease. | The Journal of the Association of Physicians of India 20091001 |
| Fluorescence properties of trans-ethyl-p-(dimethylamino) cinnamate in presence of bile acid host. | Journal of photochemistry and photobiology. B, Biology 20090904 |
| The mechanism of the cholesterol-lowering effect of water-insoluble fish protein in ovariectomised rats. | The British journal of nutrition 20090901 |
| The role of transporters in the pharmacokinetics of orally administered drugs. | Pharmaceutical research 20090901 |
| Characterization of the contents of ascending colon to which drugs are exposed after oral administration to healthy adults. | Pharmaceutical research 20090901 |
| Bile acids inhibit NAD+-dependent 15-hydroxyprostaglandin dehydrogenase transcription in colonocytes. | American journal of physiology. Gastrointestinal and liver physiology 20090901 |
| Effects of essential fatty acid deficiency on enterohepatic circulation of bile salts in mice. | American journal of physiology. Gastrointestinal and liver physiology 20090901 |
| Cerebrotendinous xanthomatosis (CTX): a treatable lipid storage disease. | Pediatric endocrinology reviews : PER 20090901 |
| Nutritional approaches to prevention and treatment of gallstones. | Alternative medicine review : a journal of clinical therapeutic 20090901 |
| Ferrocene-beta-cyclodextrin conjugates: synthesis, supramolecular behavior, and use as electrochemical sensors. | Chemistry (Weinheim an der Bergstrasse, Germany) 20090817 |
| Metabonomics study of atherosclerosis rats by ultra fast liquid chromatography coupled with ion trap-time of flight mass spectrometry. | Talanta 20090815 |
| Inhibition of nucleostemin upregulates CDX2 expression in HT29 cells in response to bile acid exposure: implications in the pathogenesis of Barrett's esophagus. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20090801 |
| Physiological concentrations of bile acids down-regulate agonist induced secretion in colonic epithelial cells. | Journal of cellular and molecular medicine 20090801 |
| Relative inhibitory activity of bile acids against 12-O-tetradecanoylphorbol-13-acetate-induced inflammation, and chenodeoxycholic acid inhibition of tumour promotion in mouse skin two-stage carcinogenesis. | The Journal of pharmacy and pharmacology 20090801 |
| Oromandibular dystonia as a complication of cerebrotendinous xanthomatosis. | Movement disorders : official journal of the Movement Disorder Society 20090715 |
| Serum bile acid profiling reflects enterohepatic detoxification state and intestinal barrier function in inflammatory bowel disease. | World journal of gastroenterology 20090707 |
| Bile acid aspiration in suspected ventilator-associated pneumonia. | Chest 20090701 |
| Bile acids inhibit duodenal secretin expression via orphan nuclear receptor small heterodimer partner (SHP). | American journal of physiology. Gastrointestinal and liver physiology 20090701 |
| Dietary procyanidins enhance transcriptional activity of bile acid-activated FXR in vitro and reduce triglyceridemia in vivo in a FXR-dependent manner. | Molecular nutrition & food research 20090701 |
| Expression and regulation of the bile acid transporter, OSTalpha-OSTbeta in rat and human intestine and liver. | Biopharmaceutics & drug disposition 20090701 |
| Monoketocholate can decrease transcellular permeation of methotrexate across Caco-2 cell monolayers and reduce its intestinal absorption in rat. | The Journal of pharmacy and pharmacology 20090701 |
| Association between farnesoid X receptor expression and cell proliferation in estrogen receptor-positive luminal-like breast cancer from postmenopausal patients. | Breast cancer research and treatment 20090601 |
| Absence of glycochenodeoxycholic acid (GCDCA) in human bile is an indication of cholestasis: a 1H MRS study. | NMR in biomedicine 20090601 |
| Ligand diversity of human and chimpanzee CYP3A4: activation of human CYP3A4 by lithocholic acid results from positive selection. | Drug metabolism and disposition: the biological fate of chemicals 20090601 |
| Effect of SLCO1B1 polymorphism on the plasma concentrations of bile acids and bile acid synthesis marker in humans. | Pharmacogenetics and genomics 20090601 |
| Differentiated CaCo-2 cells as an in-vitro model to evaluate de-novo apolipoprotein A-I production in the small intestine. | European journal of gastroenterology & hepatology 20090601 |
| Comparison of effects of VDR versus PXR, FXR and GR ligands on the regulation of CYP3A isozymes in rat and human intestine and liver. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090512 |
| Efficacy on anaplastic thyroid carcinoma of valproic acid alone or in combination with doxorubicin, a synthetic chenodeoxycholic acid derivative, or lactacystin. | International journal of oncology 20090501 |
| [Expression and regulation of megalin in gallbladder mucosa associated with cholesterol gallstone disease]. | Zhonghua yi xue za zhi 20090428 |
| Bile acid signaling pathways increase stability of Small Heterodimer Partner (SHP) by inhibiting ubiquitin-proteasomal degradation. | Genes & development 20090415 |
| [The right medicine for cerebrotendinous xanthomatosis]. | Nederlands tijdschrift voor geneeskunde 20090411 |
| Bile acid ratio in diagnosis of intrahepatic cholestasis of pregnancy. | American journal of perinatology 20090401 |
| FXR promotes endothelial cell motility through coordinated regulation of FAK and MMP-9. | Arteriosclerosis, thrombosis, and vascular biology 20090401 |
| Conversion of cholic acid and chenodeoxycholic acid into their 7-oxo derivatives by Bacteroides intestinalis AM-1 isolated from human feces. | FEMS microbiology letters 20090401 |
| Bile salts control the antimicrobial peptide cathelicidin through nuclear receptors in the human biliary epithelium. | Gastroenterology 20090401 |
| [Cerebrotendinous xanthomatosis: report of 4 patients]. | Actas dermo-sifiliograficas 20090401 |
| ATP8B1 deficiency disrupts the bile canalicular membrane bilayer structure in hepatocytes, but FXR expression and activity are maintained. | Gastroenterology 20090301 |
| Hematopoietically expressed homeobox is a target gene of farnesoid X receptor in chenodeoxycholic acid-induced liver hypertrophy. | Hepatology (Baltimore, Md.) 20090301 |
| Cholesterol-dependent anaplasma phagocytophilum exploits the low-density lipoprotein uptake pathway. | PLoS pathogens 20090301 |
| The farnesoid X receptor regulates transcription of 3beta-hydroxysteroid dehydrogenase type 2 in human adrenal cells. | Molecular and cellular endocrinology 20090227 |
| Antiatherosclerotic effect of farnesoid X receptor. | American journal of physiology. Heart and circulatory physiology 20090201 |
| Lake char (Salvelinus namaycush) olfactory neurons are highly sensitive and specific to bile acids. | Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20090201 |
| Characterization of enantiomeric bile acid-induced apoptosis in colon cancer cell lines. | The Journal of biological chemistry 20090130 |
| Effect of ursodeoxycholic acid on serum liver enzymes and bile acid metabolism in chronic active hepatitis C virus infection. | Hepatology research : the official journal of the Japan Society of Hepatology 20090101 |
| Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7alpha-hydroxylase gene expression. | Hepatology (Baltimore, Md.) 20090101 |
| Novel zinc porphyrin sensitizers for dye-sensitized solar cells: synthesis and spectral, electrochemical, and photovoltaic properties. | Chemistry (Weinheim an der Bergstrasse, Germany) 20090101 |
| Effect of guggulsterone and cembranoids of Commiphora mukul on pancreatic phospholipase A(2): role in hypocholesterolemia. | Journal of natural products 20090101 |
| Low retinol levels differentially modulate bile salt-induced expression of human and mouse hepatic bile salt transporters. | Hepatology (Baltimore, Md.) 20090101 |
| Chronic diarrhea and juvenile cataracts: think cerebrotendinous xanthomatosis and treat. | Pediatrics 20090101 |
| Bear bile: dilemma of traditional medicinal use and animal protection. | Journal of ethnobiology and ethnomedicine 20090101 |
| Biphasic regulation of cell death and survival by hydrophobic bile acids in HCT116 cells. | Nutrition and cancer 20090101 |
| Cefotaxime pharmacokinetics after oral application in the form of 3alpha,7alpha-dihydroxy-12-keto-5beta-cholanate microvesicles in rat. | European journal of drug metabolism and pharmacokinetics 20090101 |
| Gliclazide reduces MKC intestinal transport in healthy but not diabetic rats. | European journal of drug metabolism and pharmacokinetics 20090101 |
| Deoxycholate induces COX-2 expression via Erk1/2-, p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells. | BMC cancer 20090101 |
| Regulation of bile acid and cholesterol metabolism by PPARs. | PPAR research 20090101 |
| Effect of 12-monoketocholic acid on modulation of analgesic action of morphine and tramadol. | European journal of drug metabolism and pharmacokinetics 20090101 |
| Various techniques for the surgical treatment of common bile duct stones: a meta review. | Gastroenterology research and practice 20090101 |
| Regulation of sulfotransferase and UDP-glucuronosyltransferase gene expression by the PPARs. | PPAR research 20090101 |
| A new bile acid from the bile of Anser anser. | Natural product research 20090101 |
| Erythropoietic protoporphyria. | Orphanet journal of rare diseases 20090101 |
| A transcriptome analysis identifies molecular effectors of unconjugated bilirubin in human neuroblastoma SH-SY5Y cells. | BMC genomics 20090101 |
| Functional and probiotic attributes of an indigenous isolate of Lactobacillus plantarum. | PloS one 20090101 |
| Transport assays and permeability in pathogenic mycobacteria. | Methods in molecular biology (Clifton, N.J.) 20090101 |
| 7alpha- and 12alpha-Hydroxysteroid dehydrogenases from Acinetobacter calcoaceticus lwoffii: a new integrated chemo-enzymatic route to ursodeoxycholic acid. | Steroids 20081222 |
| The membrane protein ATPase class I type 8B member 1 signals through protein kinase C zeta to activate the farnesoid X receptor. | Hepatology (Baltimore, Md.) 20081201 |
| Elevated cholesterol precursors other than cholestanol can also be a hallmark for CTX. | Journal of inherited metabolic disease 20081201 |
| Physical and chemical factors influencing the germination of Clostridium difficile spores. | Journal of applied microbiology 20081201 |
| Beta-glucans in the treatment of diabetes and associated cardiovascular risks. | Vascular health and risk management 20081201 |
| Synthetic chenodeoxycholic acid derivative, HS-1200, induces apoptosis of human hepatoma cells via a mitochondrial pathway. | Cancer letters 20081108 |
| Phosphorylation of farnesoid X receptor by protein kinase C promotes its transcriptional activity. | Molecular endocrinology (Baltimore, Md.) 20081101 |
| beta-Klotho and FGF-15/19 inhibit the apical sodium-dependent bile acid transporter in enterocytes and cholangiocytes. | American journal of physiology. Gastrointestinal and liver physiology 20081101 |
| Bile acids induce CCN2 production through p38 MAP kinase activation in human bronchial epithelial cells: a factor contributing to airway fibrosis. | Respirology (Carlton, Vic.) 20081101 |
| Altered bile acid metabolism in childhood functional constipation: inactivation of secretory bile acids by sulfation in a subset of patients. | Journal of pediatric gastroenterology and nutrition 20081101 |
| FXRalpha down-regulates LXRalpha signaling at the CETP promoter via a common element. | Molecules and cells 20081031 |
| Association between fecal bile acids and colorectal cancer: a meta-analysis of observational studies. | Yonsei medical journal 20081031 |
| Synthesis of sterically hindered phthalocyanines and their applications to dye-sensitized solar cells. | Dalton transactions (Cambridge, England : 2003) 20081028 |
| Effect of coadsorbent on the photovoltaic performance of squaraine sensitized nanocrystalline solar cells. | Nanotechnology 20081022 |
| A chenodeoxycholic derivative, HS-1200, induces apoptosis and cell cycle modulation via Egr-1 gene expression control on human hepatoma cells. | Cancer letters 20081018 |
| Pyrazolidine-3,5-dione derivatives as potent non-steroidal agonists of farnesoid X receptor: virtual screening, synthesis, and biological evaluation. | Bioorganic & medicinal chemistry letters 20081015 |
| Identification of human hepatic cytochrome p450 enzymes involved in the biotransformation of cholic and chenodeoxycholic acid. | Drug metabolism and disposition: the biological fate of chemicals 20081001 |
| New lithocholic and chenodeoxycholic piperazinylcarboxamides with antiproliferative and pro-apoptotic effects on human cancer cell lines. | Bioorganic & medicinal chemistry 20080915 |
| The synthesis of MP-CDCA conjugates and dissolution kinetics of model cholesterol gallstones. | Acta biomaterialia 20080901 |
| Bile acids repress E-cadherin through the induction of Snail and increase cancer invasiveness in human hepatobiliary carcinoma. | Cancer science 20080901 |
| Effects of bile acids on pancreatic ductal bicarbonate secretion in guinea pig. | Gut 20080801 |
| Critical micellar concentrations of keto derivatives of selected bile acids: thermodynamic functions of micelle formation. | Colloids and surfaces. B, Biointerfaces 20080715 |
| Teaching neuroimage: cerebrotendinous xanthomatosis. | Neurology 20080708 |
| Impact of impurity on kinetic estimates from transport and inhibition studies. | The Journal of pharmacology and experimental therapeutics 20080701 |
| Adaptive responses of renal organic anion transporter 3 (OAT3) during cholestasis. | American journal of physiology. Renal physiology 20080701 |
| Metabolic profiling of an Echinostoma caproni infection in the mouse for biomarker discovery. | PLoS neglected tropical diseases 20080701 |
| The novel compounds that activate farnesoid X receptor: the diversity of their effects on gene expression. | Journal of pharmacological sciences 20080701 |
| Determination of bile acids in human serum by on-line restricted access material-ultra high-performance liquid chromatography-mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080615 |
| Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). | Journal of medicinal chemistry 20080612 |
| Bile acid levels are increased in the liver of patients with steatohepatitis. | European journal of gastroenterology & hepatology 20080601 |
| Effect of coadsorbent on the photovoltaic performance of zinc pthalocyanine-sensitized solar cells. | Langmuir : the ACS journal of surfaces and colloids 20080520 |
| [Effects of farnesoid X receptor ligand on the metabolism of bile acids in rats with estrogen-induced intrahepatic cholestasis of pregnancy]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20080501 |
| [Analysis of bile acid-related proteins by mass spectrometry]. | Rinsho byori. The Japanese journal of clinical pathology 20080501 |
| Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma. | Cancer research 20080415 |
| Lithocholic acid derivatives act as selective vitamin D receptor modulators without inducing hypercalcemia. | Journal of lipid research 20080401 |
| Bile acids modulate tight junction structure and barrier function of Caco-2 monolayers via EGFR activation. | American journal of physiology. Gastrointestinal and liver physiology 20080401 |
| Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies. | Journal of medicinal chemistry 20080327 |
| Activation of the farnesoid X receptor represses PCSK9 expression in human hepatocytes. | FEBS letters 20080319 |
| Activators of the farnesoid X receptor negatively regulate androgen glucuronidation in human prostate cancer LNCAP cells. | The Biochemical journal 20080301 |
| Influence of the semisynthetic bile acid MKC on the ileal permeation of gliclazide in vitro in healthy and diabetic rats treated with probiotics. | Methods and findings in experimental and clinical pharmacology 20080301 |
| Rapid screening of antineoplastic candidates for the human organic anion transporter OATP1B3 substrates using fluorescent probes. | Cancer letters 20080218 |
| FXR-mediated regulation of angiotensin type 2 receptor expression in vascular smooth muscle cells. | Cardiovascular research 20080201 |
| Comparison of the induction profile for drug disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells. | British journal of pharmacology 20080201 |
| Enhancement of genotype 1 hepatitis C virus replication by bile acids through FXR. | Journal of hepatology 20080201 |
| Systematic studies on the paracellular permeation of model permeants and oligonucleotides in the rat small intestine with chenodeoxycholate as enhancer. | Journal of pharmaceutical sciences 20080101 |
| The use of High Performance Thin-Layer Chromatography to determine the role of membrane lipid composition in bile salt-induced kidney cell damage. | Journal of pharmacological and toxicological methods 20080101 |
| Spectral-resolved gene technology for multiplexed bioluminescence and high-content screening. | Analytical chemistry 20080101 |
| Clostridium scindens baiCD and baiH genes encode stereo-specific 7alpha/7beta-hydroxy-3-oxo-delta4-cholenoic acid oxidoreductases. | Biochimica et biophysica acta 20080101 |
| Probiotic modulation of symbiotic gut microbial-host metabolic interactions in a humanized microbiome mouse model. | Molecular systems biology 20080101 |
| Role of sulphated polysaccharides from Sargassum Wightii in Cyclosporine A-induced oxidative liver injury in rats. | BMC pharmacology 20080101 |
| Effect of colonic bacterial metabolites on Caco-2 cell paracellular permeability in vitro. | Nutrition and cancer 20080101 |
| Peroxisome proliferator-activated receptor alpha activates cyclooxygenase-2 gene transcription through bile acid transport in human colorectal cancer cell lines. | Journal of gastroenterology 20080101 |
| An amphioxus orthologue of the estrogen receptor that does not bind estradiol: insights into estrogen receptor evolution. | BMC evolutionary biology 20080101 |
| Farnesoid X receptor induces GLUT4 expression through FXR response element in the GLUT4 promoter. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101 |
| Influence of sodium monoketocholate on the hypolipidemic activity of lovastatin in healthy and diabetic rats. | European journal of drug metabolism and pharmacokinetics 20080101 |
| Influence of the semisynthetic bile acid (MKC) on the ileal permeation of gliclazide in healthy and diabetic rats. | Pharmacological reports : PR 20080101 |
| N-Glycosylation of the alpha subunit does not influence trafficking or functional activity of the human organic solute transporter alpha/beta. | BMC cell biology 20080101 |
| Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes. | Molecular systems biology 20080101 |
| Bile composition in Alagille Syndrome and PFIC patients having Partial External Biliary Diversion. | BMC gastroenterology 20080101 |
| The influence of 3alpha,7alpha-dihydroxy-12-keto-5beta-cholanate on gliclazide pharmacokinetics and glucose levels in a rat model of diabetes. | European journal of drug metabolism and pharmacokinetics 20080101 |
| Deoxycholic acid induces the overexpression of intestinal mucin, MUC2, via NF-kB signaling pathway in human esophageal adenocarcinoma cells. | BMC cancer 20080101 |
| Determination of key intermediates in cholesterol and bile acid biosynthesis by stable isotope dilution mass spectrometry. | Analytical chemistry insights 20080101 |
| Organic anion transporting polypeptide 1B3 (OATP1B3) is overexpressed in colorectal tumors and is a predictor of clinical outcome. | Clinical and experimental gastroenterology 20080101 |
| Hydrophobic bile acids, genomic instability, Darwinian selection, and colon carcinogenesis. | Clinical and experimental gastroenterology 20080101 |
| Regulation of hepatic bile acid transporters Ntcp and Bsep expression. | Biochemical pharmacology 20071203 |
| Isolation and chemical synthesis of a major, novel biliary bile acid in the common wombat (Vombatus ursinus): 15alpha-hydroxylithocholic acid. | Journal of lipid research 20071201 |
| Chenodeoxycholic acid suppresses the activation of acetyl-coenzyme A carboxylase-alpha gene transcription by the liver X receptor agonist T0-901317. | Journal of lipid research 20071201 |
| Regulation of human liver delta-aminolevulinic acid synthase by bile acids. | Hepatology (Baltimore, Md.) 20071201 |
| Farnesoid x receptor ligands inhibit vascular smooth muscle cell inflammation and migration. | Arteriosclerosis, thrombosis, and vascular biology 20071201 |
| Synthesis, characterization, and receptor interaction profiles of enantiomeric bile acids. | Journal of medicinal chemistry 20071129 |
| p53 is a key molecular target of ursodeoxycholic acid in regulating apoptosis. | The Journal of biological chemistry 20071123 |
| Structural and dynamic determinants of ligand binding in the ternary complex of chicken liver bile acid binding protein with two bile salts revealed by NMR. | Biochemistry 20071106 |
| Use of selected chemical markers in combination with a multiple regression model to assess the contribution of domesticated animal sources of fecal pollution in the environment. | Chemosphere 20071101 |
| COX-2 induction by unconjugated bile acids involves reactive oxygen species-mediated signalling pathways in Barrett's oesophagus and oesophageal adenocarcinoma. | Gut 20071101 |
| Novel cytotoxic agents from an unexpected source: bile acids and ovarian tumor apoptosis. | Gynecologic oncology 20071101 |
| Activation of nuclear factor (erythroid-2 like) factor 2 by toxic bile acids provokes adaptive defense responses to enhance cell survival at the emergence of oxidative stress. | Molecular pharmacology 20071101 |
| Exposure of airway epithelium to bile acids associated with gastroesophageal reflux symptoms: a relation to transforming growth factor-beta1 production and fibroblast proliferation. | Chest 20071101 |
| Protective effect of n-3 polyunsaturated fatty acid on primary culture of rat hepatocytes. | Journal of gastroenterology and hepatology 20071101 |
| Perinatal bile acid metabolism: bile acid analysis of meconium of preterm and full-term infants. | Journal of gastroenterology 20071101 |
| Beneficial effects of hydrocortisone in induced acute pancreatitis of rats. | Chinese medical journal 20071020 |
| Protective effects of ursodeoxycholic acid on chenodeoxycholic acid-induced liver injury in hamsters. | World journal of gastroenterology 20071007 |
| NMR-based modeling and binding studies of a ternary complex between chicken liver bile acid binding protein and bile acids. | Proteins 20071001 |
| Dihydroxy bile acids increase mucosal permeability and bacterial uptake in human colon biopsies. | Scandinavian journal of gastroenterology 20071001 |
| A novel variant of ileal bile acid binding protein is up-regulated through nuclear factor-kappaB activation in colorectal adenocarcinoma. | Cancer research 20071001 |
| Nongenomic actions of bile acids. Synthesis and preliminary characterization of 23- and 6,23-alkyl-substituted bile acid derivatives as selective modulators for the G-protein coupled receptor TGR5. | Journal of medicinal chemistry 20070906 |
| The farnesoid X receptor FXRalpha/NR1H4 acquired ligand specificity for bile salts late in vertebrate evolution. | American journal of physiology. Regulatory, integrative and comparative physiology 20070901 |
| Role of bile bacteria in gallbladder carcinoma. | Hepato-gastroenterology 20070901 |
| Cerebrotendinous xanthomatosis: a treatable cause of metabolic ataxia. | The Journal of the Association of Physicians of India 20070901 |
| Lithocholic acid induction of the FGF19 promoter in intestinal cells is mediated by PXR. | World journal of gastroenterology 20070821 |
| [Cerebrotendinous xanthomatosis]. | Deutsche medizinische Wochenschrift (1946) 20070729 |
| Cloning and functional characterization of human sodium-dependent organic anion transporter (SLC10A6). | The Journal of biological chemistry 20070706 |
| Adaptive response to increased bile acids: induction of MDR1 gene expression and P-glycoprotein activity in renal epithelial cells. | Pflugers Archiv : European journal of physiology 20070701 |
| Human cecal bile acids: concentration and spectrum. | American journal of physiology. Gastrointestinal and liver physiology 20070701 |
| Rifampicin-induced CYP3A4 activation in CTX patients cannot replace chenodeoxycholic acid treatment. | Biochimica et biophysica acta 20070701 |
| Synthetic organic chemistry based on small ring compounds. | Chemical & pharmaceutical bulletin 20070701 |
| Cerebrotendinous xanthomatosis in a Saudi Arabian family-genotyping and long-term follow-up. | Saudi medical journal 20070701 |
| Downregulation of p63 upon exposure to bile salts and acid in normal and cancer esophageal cells in culture. | American journal of physiology. Gastrointestinal and liver physiology 20070701 |
| Overexpression of the cholesterol-binding protein MLN64 induces liver damage in the mouse. | World journal of gastroenterology 20070614 |
| Bile acids and lipoprotein metabolism: effects of cholestyramine and chenodeoxycholic acid on human hepatic mRNA expression. | Biochemical and biophysical research communications 20070608 |
| Ontogenic development-associated changes in the expression of genes involved in rat bile acid homeostasis. | Journal of lipid research 20070601 |
| In vivo imaging of farnesoid X receptor activity reveals the ileum as the primary bile acid signaling tissue. | Molecular endocrinology (Baltimore, Md.) 20070601 |
| Crystal structure of chenodeoxycholic acid, ursodeoxycholic acid and their two 3beta,7alpha- and 3beta,7beta-dihydroxy epimers. | Steroids 20070601 |
| Transcriptional regulation of multi-drug tolerance and antibiotic-induced responses by the histone-like protein Lsr2 in M. tuberculosis. | PLoS pathogens 20070601 |
| Can pigment gallstones be induced by biliary stricture and prevented by medicine in Guinea pigs? | World journal of gastroenterology 20070521 |
| On the mechanism of cerebral accumulation of cholestanol in patients with cerebrotendinous xanthomatosis. | Journal of lipid research 20070501 |
| Internalization of PrP106-126 by the formyl-peptide-receptor-like-1 in glial cells. | Journal of neurochemistry 20070501 |
| Design, synthesis, and evaluation of non-steroidal farnesoid X receptor (FXR) antagonist. | Bioorganic & medicinal chemistry 20070401 |
| Non-invasive analysis of gallbladder bile composition in cynomolgus monkeys using in vivo 1H magnetic resonance spectroscopy. | Biochimica et biophysica acta 20070401 |
| A novel chenodeoxycholic derivative HS-1200 enhances radiation-induced apoptosis in MCF-7 cells. | Oncology reports 20070401 |
| Why bile acid glucuronidation is a minor pathway for conjugation of endogenous bile acids in man. | Hepatology (Baltimore, Md.) 20070401 |
| Coordinated defence and the liver. | Clinical medicine (London, England) 20070401 |
| Acquisition of resistance to butyrate induces resistance to luminal components and other types of stress in human colon adenocarcinoma cells. | Toxicology in vitro : an international journal published in association with BIBRA 20070301 |
| Glycochenodeoxycholate (GCDC) inhibits cytokine induced iNOS expression in rat hepatocytes. | The Journal of surgical research 20070301 |
| Enzymes in the conversion of cholesterol into bile acids. | Current molecular medicine 20070301 |
| [Preparation and antitussive, expectorant and antiasthmatic activities of verticinone-bile acids salts]. | Yao xue xue bao = Acta pharmaceutica Sinica 20070301 |
| Bile acid-mediated thrombospondin-1 induction in hepatocytes leads to transforming growth factor-beta-dependent hepatic stellate cell activation. | Biochemical and biophysical research communications 20070223 |
| LC/ESI-tandem mass spectrometric determination of bile acid 3-sulfates in human urine 3beta-Sulfooxy-12alpha-hydroxy-5beta-cholanoic acid is an abundant nonamidated sulfate. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070201 |
| Analysis of bile acid-induced regulation of FXR target genes in human liver slices. | Liver international : official journal of the International Association for the Study of the Liver 20070201 |
| Inhibition of drug metabolism by blocking the activation of nuclear receptors by ketoconazole. | Oncogene 20070111 |
| Bile acid-induced secretion in polarized monolayers of T84 colonic epithelial cells: Structure-activity relationships. | American journal of physiology. Gastrointestinal and liver physiology 20070101 |
| In silico prediction of pregnane X receptor activators by machine learning approaches. | Molecular pharmacology 20070101 |
| Comparative study on major bioactive components in natural, artificial and in-vitro cultured Calculus Bovis. | Chemical & pharmaceutical bulletin 20070101 |
| Removal of bile acids by two different extracorporeal liver support systems in acute-on-chronic liver failure. | ASAIO journal (American Society for Artificial Internal Organs : 1992) 20070101 |
| An improved high throughput protein-protein interaction assay for nuclear hormone receptors. | Nuclear receptor signaling 20070101 |
| Bioavailability and hypoglycemic activity of the semisynthetic bile acid salt, sodium 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate, in healthy and diabetic rats. | European journal of drug metabolism and pharmacokinetics 20070101 |
| A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model. | Molecular systems biology 20070101 |
| Hexose-6-phosphate dehydrogenase modulates 11beta-hydroxysteroid dehydrogenase type 1-dependent metabolism of 7-keto- and 7beta-hydroxy-neurosteroids. | PloS one 20070101 |
| Cerebrotendinous xanthomatosis: case report with evidence of oxidative stress. | Redox report : communications in free radical research 20070101 |
| Biomarker discovery in animal health and disease: the application of post-genomic technologies. | Biomarker insights 20070101 |
| Dietary chitosan enhances hepatic CYP7A1 activity and reduces plasma and liver cholesterol concentrations in diet-induced hypercholesterolemia in rats. | Nutrition research and practice 20070101 |
| Bile acid analysis in biliary tract cancer. | Yonsei medical journal 20061231 |
| Coordinated control of bile acids and lipogenesis through FXR-dependent regulation of fatty acid synthase. | Journal of lipid research 20061201 |
| Chenodeoxycholic acid and taurochenodexycholic acid induce anti-apoptotic cIAP-1 expression in human hepatocytes. | Journal of gastroenterology and hepatology 20061201 |
| Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man. | Journal of internal medicine 20061201 |
| Modulation of the cell cycle and induction of apoptosis in human cancer cells by synthetic bile acids. | Current cancer drug targets 20061201 |
| Decreased glucagon responsiveness by bile acids: a role for protein kinase Calpha and glucagon receptor phosphorylation. | Endocrinology 20061101 |
| Constitutive androstane receptor (CAR) as a potential sensing biomarker of persistent organic pollutants (POPs) in aquatic mammal: molecular characterization, expression level, and ligand profiling in Baikal seal (Pusa sibirica). | Toxicological sciences : an official journal of the Society of Toxicology 20061101 |
| Human UDP-glucuronosyltransferase (UGT)1A3 enzyme conjugates chenodeoxycholic acid in the liver. | Hepatology (Baltimore, Md.) 20061101 |
| The farnesoid X receptor promotes adipocyte differentiation and regulates adipose cell function in vivo. | Molecular pharmacology 20061001 |
| Presenile cataract: consider cholestanol. | Archives of ophthalmology (Chicago, Ill. : 1960) 20061001 |
| The nuclear hormone receptor farnesoid X receptor (FXR) is activated by androsterone. | Endocrinology 20060901 |
| Biphasic regulation by bile acids of dermal fibroblast proliferation through regulation of cAMP production and COX-2 expression level. | American journal of physiology. Cell physiology 20060901 |
| Two loci on chromosome 9 control bile acid composition: evidence that a strong candidate gene, Cyp8b1, is not the culprit. | Journal of lipid research 20060901 |
| ORF18-disrupted mutant of Comamonas testosteroni TA441 accumulates significant amounts of 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oic acid and its derivatives after incubation with steroids. | The Journal of steroid biochemistry and molecular biology 20060901 |
| Expression and significance of ICAM-1 and its counter receptors LFA-1 and Mac-1 in experimental acute pancreatitis of rats. | World journal of gastroenterology 20060821 |
| Chenodeoxycholic acid stimulates the progression of human esophageal cancer cells: A possible mechanism of angiogenesis in patients with esophageal cancer. | International journal of cancer 20060815 |
| Identification of a lead pharmacophore for the development of potent nuclear receptor modulators as anticancer and X syndrome disease therapeutic agents. | Bioorganic & medicinal chemistry letters 20060815 |
| Suppression of bile acid synthesis by thyroid hormone in primary human hepatocytes. | World journal of gastroenterology 20060807 |
| Bile acids induce adhesion molecule expression in endothelial cells through activation of reactive oxygen species, NF-kappaB, and p38. | American journal of physiology. Heart and circulatory physiology 20060801 |
| Bile acids stimulate PKCalpha autophosphorylation and activation: role in the attenuation of prostaglandin E1-induced cAMP production in human dermal fibroblasts. | American journal of physiology. Gastrointestinal and liver physiology 20060801 |
| Influence of Verapamil and Cyclosporin A on bile acid metabolism and transport in rat liver slices. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20060801 |
| Characterization of fasted-state human intestinal fluids collected from duodenum and jejunum. | The Journal of pharmacy and pharmacology 20060801 |
| Chenodeoxycholic acid-mediated activation of the farnesoid X receptor negatively regulates hydroxysteroid sulfotransferase. | Drug metabolism and pharmacokinetics 20060801 |
| A simple and general strategy for the design of fluorescent cation sensor beads. | Organic letters 20060720 |
| Back door modulation of the farnesoid X receptor: design, synthesis, and biological evaluation of a series of side chain modified chenodeoxycholic acid derivatives. | Journal of medicinal chemistry 20060713 |
| Biliary lipid output in the early stage of acute liver failure induced by 90% hepatectomy in the rat. | The Journal of surgical research 20060701 |
| Identification of a novel bile acid in swans, tree ducks, and geese: 3alpha,7alpha,15alpha-trihydroxy-5beta-cholan-24-oic acid. | Journal of lipid research 20060701 |
| Interaction of native bile acids with human apical sodium-dependent bile acid transporter (hASBT): influence of steroidal hydroxylation pattern and C-24 conjugation. | Pharmaceutical research 20060701 |
| Chemical fingerprinting of Shexiang Baoxin Pill and simultaneous determination of its major constituents by HPLC with evaporative light scattering detection and electrospray mass spectrometric detection. | Chemical & pharmaceutical bulletin 20060701 |
| Effects of chenodeoxycholic acid and deoxycholic acid on cholesterol absorption and metabolism in humans. | Translational research : the journal of laboratory and clinical medicine 20060701 |
| Diphenylmethane skeleton as a multi-template for nuclear receptor ligands: preparation of FXR and PPAR ligands. | Bioorganic & medicinal chemistry letters 20060615 |
| Determination of three bile acids in artificial Calculus Bovis and its medicinal preparations by micellar electrokinetic capillary electrophoresis. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060606 |
| Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents. | American journal of physiology. Gastrointestinal and liver physiology 20060601 |
| Potential role of trans-inhibition of the bile salt export pump by progesterone metabolites in the etiopathogenesis of intrahepatic cholestasis of pregnancy. | Journal of hepatology 20060601 |
| Transport of fluorescent chenodeoxycholic acid via the human organic anion transporters OATP1B1 and OATP1B3. | Journal of lipid research 20060601 |
| Plasma levels of ursodeoxycholic acid in black bears, Ursus americanus: seasonal changes. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20060601 |
| Bile acids and cytokines inhibit the human cholesterol 7 alpha-hydroxylase gene via the JNK/c-jun pathway in human liver cells. | Hepatology (Baltimore, Md.) 20060601 |
| Single-step analysis of individual conjugated bile acids in human bile using 1H NMR spectroscopy. | Lipids 20060601 |
| Bile acid promotes the proliferation of squamous cell carcinoma of the esophagus, independent of its inducing COX-2 expression. | The Journal of surgical research 20060501 |
| The human organic cation transporter-1 gene is transactivated by hepatocyte nuclear factor-4alpha. | The Journal of pharmacology and experimental therapeutics 20060501 |
| Functional expression of sinusoidal and canalicular hepatic drug transporters in the differentiated human hepatoma HepaRG cell line. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060501 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Pharmacophore model for bile acids recognition by the FPR receptor. | Journal of computer-aided molecular design 20060501 |
| Bile acid-mediated induction of cyclooxygenase-2 and Mcl-1 in hepatic stellate cells. | Biochemical and biophysical research communications 20060421 |
| Exploitation of the alcohol dehydrogenase-acetone NADP-regeneration system for the enzymatic preparative-scale production of 12-ketochenodeoxycholic acid. | Biotechnology and bioengineering 20060420 |
| Could steroids mask the diagnosis of cerebrotendinous xanthomatosis? | Journal of the neurological sciences 20060415 |
| The region of CQQQKPQRRP of PGC-1alpha interacts with the DNA-binding complex of FXR/RXRalpha. | Biochemical and biophysical research communications 20060414 |
| NMR dynamic studies suggest that allosteric activation regulates ligand binding in chicken liver bile acid-binding protein. | The Journal of biological chemistry 20060407 |
| 11Beta-hydroxysteroid dehydrogenase type 2 and the regulation of surfactant protein A by dexamethasone metabolites. | American journal of physiology. Endocrinology and metabolism 20060401 |
| Activation of the farnesoid X receptor improves lipid metabolism in combined hyperlipidemic hamsters. | American journal of physiology. Endocrinology and metabolism 20060401 |
| Bile acid profiles by capillary electrophoresis in intrahepatic cholestasis of pregnancy. | Clinical science (London, England : 1979) 20060401 |
| Oxysterol 22(R)-hydroxycholesterol induces the expression of the bile salt export pump through nuclear receptor farsenoid X receptor but not liver X receptor. | The Journal of pharmacology and experimental therapeutics 20060401 |
| Fish oil increases bile acid synthesis in male patients with hypertriglyceridemia. | The Journal of nutrition 20060401 |
| Farnesoid X receptor, hepatocyte nuclear factors 1alpha and 3beta are essential for transcriptional activation of the liver-specific organic anion transporter-2 gene. | Journal of gastroenterology 20060401 |
| Retrograded tapioca starch prevents ovarian hormone deficiency-induced hypercholesterolemia. | Journal of nutritional science and vitaminology 20060401 |
| Hepatocyte nuclear factor-4alpha plays pivotal roles in the regulation of mouse carboxylesterase 2 gene transcription in mouse liver. | Archives of biochemistry and biophysics 20060315 |
| Modulation of cholesterol metabolism by the green tea polyphenol (-)-epigallocatechin gallate in cultured human liver (HepG2) cells. | Journal of agricultural and food chemistry 20060308 |
| The nuclear receptor for bile acids, FXR, transactivates human organic solute transporter-alpha and -beta genes. | American journal of physiology. Gastrointestinal and liver physiology 20060301 |
| Tibolone metabolism in human liver is catalyzed by 3alpha/3beta-hydroxysteroid dehydrogenase activities of the four isoforms of the aldo-keto reductase (AKR)1C subfamily. | The Journal of pharmacology and experimental therapeutics 20060301 |
| Bile acid transport and metabolism in rat liver slices. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20060301 |
| Vectorial transport of unconjugated and conjugated bile salts by monolayers of LLC-PK1 cells doubly transfected with human NTCP and BSEP or with rat Ntcp and Bsep. | American journal of physiology. Gastrointestinal and liver physiology 20060301 |
| 1,25-dihydroxyvitamin D3 and its receptor inhibit the chenodeoxycholic acid-dependent transactivation by farnesoid X receptor. | The Journal of endocrinology 20060301 |
| Immunoaffinity extraction of a peptide modified by a small molecule. | Analytical biochemistry 20060215 |
| Nuclear receptors, bile-acid detoxification, and cholestasis. | Lancet (London, England) 20060211 |
| Downregulation of endothelin-1 by farnesoid X receptor in vascular endothelial cells. | Circulation research 20060203 |
| A role for FXR and human FGF-19 in the repression of paraoxonase-1 gene expression by bile acids. | Journal of lipid research 20060201 |
| Studies of serum and feces bile acids determination by gas chromatography-mass spectrometry. | Rinsho byori. The Japanese journal of clinical pathology 20060201 |
| Molecular adsorbent recirculating system (MARS) application in liver failure: clinical and hemodepurative results in 22 patients. | The International journal of artificial organs 20060201 |
| FXR regulates organic solute transporters alpha and beta in the adrenal gland, kidney, and intestine. | Journal of lipid research 20060101 |
| Micellization of conjugated chenodeoxy- and ursodeoxycholates and solubilization of cholesterol into their micelles: comparison with other four conjugated bile salts species. | Chemistry and physics of lipids 20060101 |
| Enhancement of DNA topoisomerase I inhibitor-induced apoptosis by ursodeoxycholic acid. | Molecular cancer therapeutics 20060101 |
| Bile acid metabolism in extrahepatic biliary atresia: lithocholic acid in stored dried blood collected at neonatal screening. | Upsala journal of medical sciences 20060101 |
| Laparoscopic common bile duct exploration in pregnancy with acute gallstone pancreatitis. | JSLS : Journal of the Society of Laparoendoscopic Surgeons 20060101 |
| Influence of charge and steric bulk in the C-24 region on the interaction of bile acids with human apical sodium-dependent bile acid transporter. | Molecular pharmaceutics 20060101 |
| Chenodeoxycholic acid reduce bacterial translocation in sepsis. | Medical hypotheses 20060101 |
| State-of-art methodology of marine natural products chemistry: structure determination with extremely small sample amounts. | Progress in molecular and subcellular biology 20060101 |
| Resistance to ursodeoxycholic acid-induced growth arrest can also result in resistance to deoxycholic acid-induced apoptosis and increased tumorgenicity. | BMC cancer 20060101 |
| Cerebrotendinous xanthomatosis: need for early diagnosis. | Indian journal of dermatology, venereology and leprology 20060101 |
| Expression of the bile acid receptor FXR in Barrett's esophagus and enhancement of apoptosis by guggulsterone in vitro. | Molecular cancer 20060101 |
| Autosomal recessive cerebellar ataxias. | Orphanet journal of rare diseases 20060101 |
| Chemical and metabolic transformations of selected bile acids. | European journal of drug metabolism and pharmacokinetics 20060101 |
| Pharmacology of bile acids and their derivatives: absorption promoters and therapeutic agents. | European journal of drug metabolism and pharmacokinetics 20060101 |
| Increased serum concentrations of secondary bile salts during cholate feeding are due to coprophagy. A study with wild-type and Atp8b1-deficient mice. | Molecular pharmaceutics 20060101 |
| [Effect of thromboxane B2 on morphological features of apoptosis in cultured rat hepatocytes exposed to hepatotropic substances]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20060101 |
| FTF and LRH-1, two related but different transcription factors in human Caco-2 cells: their different roles in the regulation of bile acid transport. | Biochimica et biophysica acta 20051230 |
| Ileal bile acid-binding protein, functionally associated with the farnesoid X receptor or the ileal bile acid transporter, regulates bile acid activity in the small intestine. | The Journal of biological chemistry 20051223 |
| Effect of a coadsorbent on the performance of dye-sensitized TiO2 solar cells: shielding versus band-edge movement. | The journal of physical chemistry. B 20051215 |
| Unusual cerebrotendinous xanthomatosis with fronto-temporal dementia phenotype. | American journal of medical genetics. Part A 20051201 |
| Conjugated bile acids promote ERK1/2 and AKT activation via a pertussis toxin-sensitive mechanism in murine and human hepatocytes. | Hepatology (Baltimore, Md.) 20051201 |
| Tissue-specific, inducible, and hormonal control of the human UDP-glucuronosyltransferase-1 (UGT1) locus. | The Journal of biological chemistry 20051111 |
| Synthetic bile acid derivatives induce apoptosis through a c-Jun N-terminal kinase and NF-kappaB-dependent process in human cervical carcinoma cells. | Cancer letters 20051108 |
| Bile acids reduce SR-BI expression in hepatocytes by a pathway involving FXR/RXR, SHP, and LRH-1. | Biochemical and biophysical research communications 20051104 |
| Xanthohumol, the chalcone from beer hops (Humulus lupulus L.), is the ligand for farnesoid X receptor and ameliorates lipid and glucose metabolism in KK-A(y) mice. | Biochemical and biophysical research communications 20051028 |
| Cross-talk between farnesoid-X-receptor (FXR) and peroxisome proliferator-activated receptor gamma contributes to the antifibrotic activity of FXR ligands in rodent models of liver cirrhosis. | The Journal of pharmacology and experimental therapeutics 20051001 |
| 1H and 13C NMR characterization and stereochemical assignments of bile acids in aqueous media. | Lipids 20051001 |
| Impaired proximal colonic motor response to rectal mechanical and chemical stimulation in obstructed defecation. | Diseases of the colon and rectum 20050901 |
| VPAC1 expression is regulated by FXR agonists in the human gallbladder epithelium. | Hepatology (Baltimore, Md.) 20050901 |
| Downregulation of TACO gene transcription restricts mycobacterial entry/survival within human macrophages. | FEMS microbiology letters 20050901 |
| Synthetic chenodeoxycholic acid derivatives inhibit glioblastoma multiform tumor growth in vitro and in vivo. | International journal of oncology 20050901 |
| Effect of Larrea tridentata (creosote bush) on cholesterol gallstones and bile secretion in hamsters. | The Journal of pharmacy and pharmacology 20050901 |
| Cerebrotendinous xanthomatosis: possible higher prevalence than previously recognized. | Archives of neurology 20050901 |
| Bile acid signaling through FXR induces intracellular adhesion molecule-1 expression in mouse liver and human hepatocytes. | American journal of physiology. Gastrointestinal and liver physiology 20050801 |
| A farnesoid x receptor-small heterodimer partner regulatory cascade modulates tissue metalloproteinase inhibitor-1 and matrix metalloprotease expression in hepatic stellate cells and promotes resolution of liver fibrosis. | The Journal of pharmacology and experimental therapeutics 20050801 |
| The methyl transferase PRMT1 functions as co-activator of farnesoid X receptor (FXR)/9-cis retinoid X receptor and regulates transcription of FXR responsive genes. | Molecular pharmacology 20050801 |
| Development of stably transfected monolayer overexpressing the human apical sodium-dependent bile acid transporter (hASBT). | Pharmaceutical research 20050801 |
| Characteristics of apoptosis in HCT116 colon cancer cells induced by deoxycholic acid. | Journal of biochemistry 20050801 |
| Lithocholic acid decreases expression of UGT2B7 in Caco-2 cells: a potential role for a negative farnesoid X receptor response element. | Drug metabolism and disposition: the biological fate of chemicals 20050701 |
| Serum bile acid profile in women during pregnancy and childbed. | Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20050701 |
| Pretreatment with ursodeoxycholic acid (UDCA) as a novel pharmacological intervention in hepatobiliary scintigraphy. | Yonsei medical journal 20050630 |
| Regulation of ileal bile acid-binding protein expression in Caco-2 cells by ursodeoxycholic acid: role of the farnesoid X receptor. | Biochemical pharmacology 20050615 |
| The mechanism underlying the contractile effect of a chemotactic peptide, formyl-Met-Leu-Phe on the guinea-pig Taenia coli. | British journal of pharmacology 20050601 |
| The cell envelope structure and properties of Mycobacterium smegmatis mc(2)155: is there a clue for the unique transformability of the strain? | Microbiology (Reading, England) 20050601 |
| Induction of human cholesterol 7alpha-hydroxylase in HepG2 cells by 2,4,6-trihydroxyacetophenone. | European journal of pharmacology 20050516 |
| Transient changes in the expression pattern of key enzymes for bile acid synthesis during rat liver regeneration. | Biochimica et biophysica acta 20050515 |
| Feedback regulation of bile acid synthesis in human liver: importance of HNF-4alpha for regulation of CYP7A1. | Biochemical and biophysical research communications 20050506 |
| Protective effects of 6-ethyl chenodeoxycholic acid, a farnesoid X receptor ligand, in estrogen-induced cholestasis. | The Journal of pharmacology and experimental therapeutics 20050501 |
| The human organic anion transporter 2 gene is transactivated by hepatocyte nuclear factor-4 alpha and suppressed by bile acids. | Molecular pharmacology 20050501 |
| Cerebrotendinous xanthomatosis: a treatable ataxia. | Neurology 20050426 |
| Bile acids induce MUC2 overexpression in human colon carcinoma cells. | Cancer 20050415 |
| Cytokine regulation of human sterol 12alpha-hydroxylase (CYP8B1) gene. | American journal of physiology. Gastrointestinal and liver physiology 20050401 |
| Chemical synthesis of 24-beta-D-galactopyranosides of bile acids: a new type of bile acid conjugates in human urine. | Chemistry and physics of lipids 20050401 |
| Inhibition of hepatocyte growth factor production in human fibroblasts by ursodeoxycholic acid. | Biological & pharmaceutical bulletin 20050401 |
| Usefulness of combined measurement of serum bile acids and ferritin as additional prognostic markers to predict failure to reach sustained response to antiviral treatment in chronic hepatitis C. | Journal of gastroenterology and hepatology 20050401 |
| Increasing ursodeoxycholic acid in the enterohepatic circulation of pigs through the administration of living bacteria. | The British journal of nutrition 20050401 |
| Interfacial properties of most monofluorinated bile acids deviate markedly from the natural congeners: studies with the Langmuir-Pockels surface balance. | Journal of lipid research 20050301 |
| Isotopomer spectral analysis of intermediates of cholesterol synthesis in patients with cerebrotendinous xanthomatosis. | Metabolism: clinical and experimental 20050301 |
| A new drug carrier, Nalpha-deoxycholyl-L: -lysyl-methylester, for enhancing insulin absorption in the intestine. | Diabetologia 20050301 |
| Bile-induced laryngitis: is there a basis in evidence? | The Annals of otology, rhinology, and laryngology 20050301 |
| Disrupted coordinate regulation of farnesoid X receptor target genes in a patient with cerebrotendinous xanthomatosis. | Journal of lipid research 20050201 |
| Species-specific mechanisms for cholesterol 7alpha-hydroxylase (CYP7A1) regulation by drugs and bile acids. | Archives of biochemistry and biophysics 20050201 |
| Measurement of hepatic functional mass by means of 13C-methacetin and 13C-phenylalanine breath tests in chronic liver disease: comparison with Child-Pugh score and serum bile acid levels. | World journal of gastroenterology 20050107 |
| Vectorial transport of bile salts across MDCK cells expressing both rat Na+-taurocholate cotransporting polypeptide and rat bile salt export pump. | American journal of physiology. Gastrointestinal and liver physiology 20050101 |
| Expression of macrophage migration inhibitory factor in esophageal squamous cell carcinoma and effects of bile acids and NSAIDs. | Carcinogenesis 20050101 |
| Selective activation of vitamin D receptor by lithocholic acid acetate, a bile acid derivative. | Journal of lipid research 20050101 |
| Bile acid induced gene expression in LT97 colonic adenoma cells. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050101 |
| FXR-activating ligands inhibit rabbit ASBT expression via FXR-SHP-FTF cascade. | American journal of physiology. Gastrointestinal and liver physiology 20050101 |
| Esophageal visceral sensitivity to bile salts in patients with functional heartburn and in healthy control subjects. | Digestive diseases and sciences 20050101 |
| [Differential approach to detection and treatment of cholelithiasis in outpatient conditions]. | Terapevticheskii arkhiv 20050101 |
| Inhibition of MRP1-mediated efflux in human erythrocytes by mono-anionic bile salts. | Anticancer research 20050101 |
| Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors). | Nuclear receptor 20050101 |
| Polymorphism in the coding part of the sterol 12alpha-hydroxylase gene does not explain the marked differences in the ratio of cholic acid and chenodeoxycholic acid in human bile. | Scandinavian journal of clinical and laboratory investigation 20050101 |
| Inherited cholesterol lipidosis: cerebrotendinous xanthomatosis (van Bogaert Scherer Epstein disease). A clinicopathological study. | Clinical neuropathology 20050101 |
| Effects of a 3-mo consumption of short-chain fructo-oligosaccharides on parameters of colorectal carcinogenesis in patients with or without small or large colorectal adenomas. | Nutrition and cancer 20050101 |
| Effect of bile acids on butyrate-sensitive and -resistant human colon adenocarcinoma cells. | Nutrition and cancer 20050101 |
| Determination of underivatised sterols and bile acid trimethyl silyl ether methyl esters by gas chromatography-mass spectrometry-single ion monitoring in faeces. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225 |
| Effects of bile acids on proliferation and production of proteinase activity of Uronema marinum (Ciliophora: Scuticociliatida). | Diseases of aquatic organisms 20041213 |
| Megalin and cubilin expression in gallbladder epithelium and regulation by bile acids. | Journal of lipid research 20041201 |
| Farnesoid X receptor represses hepatic lipase gene expression. | Journal of lipid research 20041101 |
| The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis. | Gastroenterology 20041101 |
| Multidrug resistance3 is in situ detected in the liver of patients with primary biliary cirrhosis, and induced in human hepatoma cells by bezafibrate. | Hepatology research : the official journal of the Japan Society of Hepatology 20041101 |
| Bile acid reduces the secretion of very low density lipoprotein by repressing microsomal triglyceride transfer protein gene expression mediated by hepatocyte nuclear factor-4. | The Journal of biological chemistry 20041029 |
| Effects of meal frequency and high-fibre rye-bread diet on glucose and lipid metabolism and ileal excretion of energy and sterols in ileostomy subjects. | European journal of clinical nutrition 20041001 |
| Sterol-derived hormone(s) controls entry into diapause in Caenorhabditis elegans by consecutive activation of DAF-12 and DAF-16. | PLoS biology 20041001 |
| Normalisation of serum cholestanol concentration in a patient with cerebrotendinous xanthomatosis by combined treatment with chenodeoxycholic acid, simvastatin and LDL apheresis. | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20041001 |
| The nuclear bile acid receptor FXR is activated by PGC-1alpha in a ligand-dependent manner. | The Biochemical journal 20040915 |
| Bioconversion of 3beta-hydroxy-5-cholenoic acid into chenodeoxycholic acid by rat brain enzyme systems. | Journal of lipid research 20040901 |
| The farnesoid X receptor: a novel drug target? | Expert opinion on investigational drugs 20040901 |
| Ursodeoxycholate/Sulindac combination treatment effectively prevents intestinal adenomas in a mouse model of polyposis. | Gastroenterology 20040901 |
| DNA hypomethylation induced by non-genotoxic carcinogens in mouse and rat colon. | Cancer letters 20040830 |
| Bile acid derivatives as ligands of the farnesoid X receptor. Synthesis, evaluation, and structure-activity relationship of a series of body and side chain modified analogues of chenodeoxycholic acid. | Journal of medicinal chemistry 20040826 |
| Identification of intermediates in the bile acid synthetic pathway as ligands for the farnesoid X receptor. | Journal of lipid research 20040801 |
| Polyunsaturated fatty acids are FXR ligands and differentially regulate expression of FXR targets. | DNA and cell biology 20040801 |
| Synthetic bile acid derivatives inhibit cell proliferation and induce apoptosis in HT-29 human colon cancer cells. | International journal of oncology 20040701 |
| Cyclosporine A-induced reduction of bile salt synthesis associated with increased plasma lipids in children after liver transplantation. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20040701 |
| Bile acid-induced negative feedback regulation of the human ileal bile acid transporter. | Hepatology (Baltimore, Md.) 20040701 |
| [Menthol in the adjuvant treatment of gallbladder stones fragmented by ESWL as an option for reducing doses of urso- and chenodeoxycholic acid]. | Medizinische Klinik (Munich, Germany : 1983) 20040615 |
| Epimerization of chenodeoxycholic acid to ursodeoxycholic acid by Clostridium baratii isolated from human feces. | FEMS microbiology letters 20040601 |
| Effect of chenodeoxycholic acid on 11beta-hydroxysteroid dehydrogenase in various target tissues. | Metabolism: clinical and experimental 20040601 |
| Short-step synthesis of chenodiol from stigmasterol. | Bioscience, biotechnology, and biochemistry 20040601 |
| [Cerebrotendinous xanthomatosis--a treatable metabolic disorder]. | Der Nervenarzt 20040601 |
| The bile acid nuclear receptor FXR and the bile acid binding protein IBABP are differently expressed in colon cancer. | Digestive diseases and sciences 20040601 |
| Production of prostaglandinE2 via bile acid is enhanced by trypsin and acid in normal human esophageal epithelial cells. | Life sciences 20040521 |
| The farnesoid X receptor induces very low density lipoprotein receptor gene expression. | FEBS letters 20040521 |
| Ion-selective electrodes based on molecular tweezer-type neutral carriers. | Talanta 20040510 |
| Role of mitochondrial dysfunction in combined bile acid-induced cytotoxicity: the switch between apoptosis and necrosis. | Toxicological sciences : an official journal of the Society of Toxicology 20040501 |
| Hydrophilic 7 beta-hydroxy bile acids, lovastatin, and cholestyramine are ineffective in the treatment of cerebrotendinous xanthomatosis. | Metabolism: clinical and experimental 20040501 |
| [Studies on mechanism of antiasthmatic and anti-inflammatory actions of CDCA]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040401 |
| The farnesoid X receptor controls gene expression in a ligand- and promoter-selective fashion. | The Journal of biological chemistry 20040305 |
| Bile acids induce cyclooxygenase-2 expression in human pancreatic cancer cell lines. | Carcinogenesis 20040301 |
| [Studies on antitussive, antiasthmatic and expectorant action of chenodeoxycholine acid]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20040301 |
| Inhibitory effect of the small heterodimer partner on hepatocyte nuclear factor-4 mediates bile acid-induced repression of the human angiotensinogen gene. | The Journal of biological chemistry 20040227 |
| Serum bile acids and risk factors for colorectal cancer. | British journal of cancer 20040209 |
| Presence of protein-bound unconjugated bile acids in the cytoplasmic fraction of rat brain. | Journal of lipid research 20040201 |
| Cerebrotendinous xanthomatosis: clinical course, genotypes and metabolic backgrounds. | Clinical and investigative medicine. Medecine clinique et experimentale 20040201 |
| Increased acyclovir oral bioavailability via a bile acid conjugate. | Molecular pharmaceutics 20040112 |
| Facile synthesis, aggregation behavior, and cholesterol solubilization ability of avicholic acid. | Organic letters 20040108 |
| Structure-activity relationship of bile acids and bile acid analogs in regard to FXR activation. | Journal of lipid research 20040101 |
| Cross-resistance to antibiotics of Escherichia coli adapted to benzalkonium chloride or exposed to stress-inducers. | Journal of applied microbiology 20040101 |
| Cholesterol-lowering properties of Ganoderma lucidum in vitro, ex vivo, and in hamsters and minipigs. | Lipids in health and disease 20040101 |
| 3Alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate as blood-brain barrier permeator. | Polish journal of pharmacology 20040101 |
| Comparison among fecal secondary bile acid levels, fecal microbiota and Clostridium scindens cell numbers in Japanese. | Microbiology and immunology 20040101 |
| Enhanced susceptibility of LDL to oxidative modification in a CTX patient:- role of chenodeoxycholic acid in xanthoma formation. | Journal of atherosclerosis and thrombosis 20040101 |
| T0901317 is a dual LXR/FXR agonist. | Molecular genetics and metabolism 20040101 |
| Farnesoid X receptor activates transcription of the phospholipid pump MDR3. | The Journal of biological chemistry 20031219 |
| Combined treatment with LDL-apheresis, chenodeoxycholic acid and HMG-CoA reductase inhibitor for cerebrotendinous xanthomatosis. | Journal of the neurological sciences 20031215 |
| Fluorescence resonance energy transfer in a novel cyclodextrin-peptide conjugate for detecting steroid molecules. | Bioorganic & medicinal chemistry letters 20031215 |
| Hepatoprotection by the farnesoid X receptor agonist GW4064 in rat models of intra- and extrahepatic cholestasis. | The Journal of clinical investigation 20031201 |
| In vitro farnesoid X receptor ligand sensor assay using surface plasmon resonance and based on ligand-induced coactivator association. | The Journal of steroid biochemistry and molecular biology 20031201 |
| Impairment of blood rheology by cholestatic jaundice in human beings. | The Journal of laboratory and clinical medicine 20031201 |
| Cloning and characterization of the NAD-dependent 7alpha-Hydroxysteroid dehydrogenase from Bacteroides fragilis. | Current microbiology 20031201 |
| Orphan nuclear receptor Nur77 translocates to mitochondria in the early phase of apoptosis induced by synthetic chenodeoxycholic acid derivatives in human stomach cancer cell line SNU-1. | Annals of the New York Academy of Sciences 20031201 |
| Micelle formation of sodium chenodeoxycholate and solubilization into the micelles: comparison with other unconjugated bile salts. | Biochimica et biophysica acta 20031115 |
| Substrate specificities of rat oatp1 and ntcp: implications for hepatic organic anion uptake. | American journal of physiology. Gastrointestinal and liver physiology 20031101 |
| Bile acid composition in snake bile juice and toxicity of snake bile acids to rats. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20031101 |
| Metabolic changes in Clostridium absonum ATCC 27555 accompanying induction of epimerization of a primary bile acid. | Current microbiology 20031101 |
| Ligand-binding domain of farnesoid X receptor (FXR) had the highest sensitivity and activity among FXR variants in a fluorescence-based assay. | Lipids 20031101 |
| Gallstones - approach to medical management. | MedGenMed : Medscape general medicine 20031015 |
| Steroid ring hydroxylation patterns govern cooperativity in human bile acid binding protein. | Biochemistry 20031014 |
| Mutations in SRD5B1 (AKR1D1), the gene encoding delta(4)-3-oxosteroid 5beta-reductase, in hepatitis and liver failure in infancy. | Gut 20031001 |
| Inhibition of the rat hepatic microsomal flurbiprofen acyl glucuronidation by bile acids. | Journal of pharmaceutical sciences 20031001 |
| Feedback regulation of bile acid synthesis in primary human hepatocytes: evidence that CDCA is the strongest inhibitor. | Hepatology (Baltimore, Md.) 20031001 |
| Biliary diversion for progressive familial intrahepatic cholestasis: improved liver morphology and bile acid profile. | Gastroenterology 20031001 |
| Apoptosis and modulation of cell cycle control by synthetic derivatives of ursodeoxycholic acid and chenodeoxycholic acid in human prostate cancer cells. | Cancer letters 20030925 |
| The small heterodimer partner interacts with the pregnane X receptor and represses its transcriptional activity. | Molecular endocrinology (Baltimore, Md.) 20030901 |
| Cerebrotendinous xanthomatosis: clinical manifestations, diagnostic criteria, pathogenesis, and therapy. | Journal of child neurology 20030901 |
| Regulation of human sterol 27-hydroxylase gene (CYP27A1) by bile acids and hepatocyte nuclear factor 4alpha (HNF4alpha). | Gene 20030814 |
| Human kininogen gene is transactivated by the farnesoid X receptor. | The Journal of biological chemistry 20030801 |
| Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis. | Genes & development 20030701 |
| Binding mode of 6ECDCA, a potent bile acid agonist of the farnesoid X receptor (FXR). | Bioorganic & medicinal chemistry letters 20030602 |
| Synergism between nuclear receptors bound to specific hormone response elements of the hepatic control region-1 and the proximal apolipoprotein C-II promoter mediate apolipoprotein C-II gene regulation by bile acids and retinoids. | The Biochemical journal 20030601 |
| Synergistic role of 3-hydroxy-3-methylglutaryl coenzyme A reductase and cholesterol 7alpha-hydroxylase in the pathogenesis of manganese-bilirubin-induced cholestasis in rats. | Toxicological sciences : an official journal of the Society of Toxicology 20030601 |
| Hydrophilic but not hydrophobic bile acids prevent gallbladder muscle dysfunction in acute cholecystitis. | Hepatology (Baltimore, Md.) 20030601 |
| Bile acid induces cyclo-oxygenase-2 expression in cultured human pharyngeal cells: a possible mechanism of carcinogenesis in the upper aerodigestive tract by laryngopharyngeal reflux. | The Laryngoscope 20030601 |
| FXR induces the UGT2B4 enzyme in hepatocytes: a potential mechanism of negative feedback control of FXR activity. | Gastroenterology 20030601 |
| Influence of ethinyloestradiol propanolsulphonate on serum bile acids in healthy volunteers. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030601 |
| Liver receptor homologue-1 mediates species- and cell line-specific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter. | The Journal of biological chemistry 20030530 |
| Syndecan-1 expression is regulated in an isoform-specific manner by the farnesoid-X receptor. | The Journal of biological chemistry 20030530 |
| Regulation of oxysterol 7alpha-hydroxylase (CYP7B1) in the rat. | Metabolism: clinical and experimental 20030501 |
| Guggulsterone antagonizes farnesoid X receptor induction of bile salt export pump but activates pregnane X receptor to inhibit cholesterol 7alpha-hydroxylase gene. | Biochemical and biophysical research communications 20030425 |
| Regression of diaphyseal multiloculated bone cyst in familial steroid dehydrogenase deficiency. | Journal of pediatric gastroenterology and nutrition 20030401 |
| A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR. | Molecular cell 20030401 |
| Gum arabic (GA) modifies paracellular water and electrolyte transport in the small intestine. | Digestive diseases and sciences 20030401 |
| Retinoid X receptor (RXR) agonist-induced antagonism of farnesoid X receptor (FXR) activity due to absence of coactivator recruitment and decreased DNA binding. | The Journal of biological chemistry 20030321 |
| Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump. | The Journal of biological chemistry 20030321 |
| Inhibitory effects of ursodeoxycholic acid on the induction of nitric oxide synthase in vascular smooth muscle cells. | European journal of pharmacology 20030319 |
| A G protein-coupled receptor responsive to bile acids. | The Journal of biological chemistry 20030314 |
| Differentiated thermal crystallization from amorphous chenodeoxycholic acid between the ground specimens derived from the polymorphs. | International journal of pharmaceutics 20030306 |
| Hepatocyte nuclear factor 1 alpha: a key mediator of the effect of bile acids on gene expression. | Hepatology (Baltimore, Md.) 20030301 |
| Synthetic chenodeoxycholic acid derivative HS-1200-induced apoptosis of p815 mastocytoma cells is augmented by co-treatment with lactacystin. | Anti-cancer drugs 20030301 |
| Chenodeoxycholate induction of mitochondrial permeability transition pore is associated with increased membrane fluidity and cytochrome c release: protective role of carvedilol. | Mitochondrion 20030301 |
| Identification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearance. | Proceedings of the National Academy of Sciences of the United States of America 20030204 |
| Upregulation of the oncogene c-myc in Barrett's adenocarcinoma: induction of c-myc by acidified bile acid in vitro. | Gut 20030201 |
| Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7. | Biochemical pharmacology 20030201 |
| Bile acids induce the expression of the human peroxisome proliferator-activated receptor alpha gene via activation of the farnesoid X receptor. | Molecular endocrinology (Baltimore, Md.) 20030201 |
| Increase of bile acid production by tacrolimus in the rat liver. | Transplantation proceedings 20030201 |
| Mitochondrially mediated synergistic cell killing by bile acids. | Biochimica et biophysica acta 20030120 |
| Influence of breast feeding, and adapted and hydrolyzed formulas on biliary bile acids in newborn guinea pigs. | Biology of the neonate 20030101 |
| Role of MR imaging in the diagnosis of cerebrotendinous xanthogranulomatosis, case report and review of literature. | La Radiologia medica 20030101 |
| Taurochenodeoxycholic acid induced biphasic hepatotoxicity in isolated perfused rat liver: roles of Ca2+ and calpain. | Hepato-gastroenterology 20030101 |
| The cytotoxicity of hydrophobic bile acids is ameliorated by more hydrophilic bile acids in intestinal cell lines IEC-6 and Caco-2. | Oncology reports 20030101 |
| Cholestanol metabolism, molecular pathology, and nutritional implications. | Journal of medicinal food 20030101 |
| Reproducibility of the serum lipid response to coffee oil in healthy volunteers. | Nutrition journal 20030101 |
| [Cerebrotendinous xanthomatosis, a treatable metabolic disorder]. | Der Nervenarzt 20021201 |
| [Cerebrotendinous xanthomatosis without tendinous xanthomas: presentation of two cases]. | Neurologia (Barcelona, Spain) 20021201 |
| Selective inhibition of CYP27A1 and of chenodeoxycholic acid synthesis in cholestatic hamster liver. | Biochimica et biophysica acta 20021120 |
| Identification of membrane-type receptor for bile acids (M-BAR). | Biochemical and biophysical research communications 20021115 |
| Bile acids enhance low density lipoprotein receptor gene expression via a MAPK cascade-mediated stabilization of mRNA. | The Journal of biological chemistry 20021004 |
| Bile acids stimulate invasion and haptotaxis in human colorectal cancer cells through activation of multiple oncogenic signaling pathways. | Oncogene 20021003 |
| The impact of the absence of glycopeptidolipids on the ultrastructure, cell surface and cell wall properties, and phagocytosis of Mycobacterium smegmatis. | Microbiology (Reading, England) 20021001 |
| Potential bile acid metabolites. 25. Synthesis and chemical properties of stereoisomeric 3alpha,7alpha,16- and 3alpha,7alpha,15-trihydroxy-5beta-cholan-24-oic acids. | Chemical & pharmaceutical bulletin 20021001 |
| Mutations in the sterol 27-hydroxylase gene (CYP27A) cause hepatitis of infancy as well as cerebrotendinous xanthomatosis. | Journal of inherited metabolic disease 20021001 |
| Effect of chenodeoxycholic acid on the toxicity of 5alpha-cyprinol sulfate in rats. | Toxicology 20020930 |
| Synthesis of [3,4-(13)c(2)]-enriched bile salts as NMR probes of protein-ligand interactions. | The Journal of organic chemistry 20020920 |
| Regulation of hepatic low-density lipoprotein receptor, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and cholesterol 7alpha-hydroxylase mRNAs in human liver. | The Journal of clinical endocrinology and metabolism 20020901 |
| A monoclonal antibody-based enzyme-linked immunosorbent assay of glycolithocholic acid sulfate in human urine for liver function test. | Steroids 20020901 |
| Lithocholic acid decreases expression of bile salt export pump through farnesoid X receptor antagonist activity. | The Journal of biological chemistry 20020830 |
| 6alpha-ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity. | Journal of medicinal chemistry 20020815 |
| Changes in bile acid composition and effect on cytolytic activity of fecal water by ursodeoxycholic acid administration: a placebo-controlled cross-over intervention trial in healthy volunteers. | Scandinavian journal of gastroenterology 20020801 |
| Differences in the regulation of the classical and the alternative pathway for bile acid synthesis in human liver. No coordinate regulation of CYP7A1 and CYP27A1. | The Journal of biological chemistry 20020726 |
| The amino acid residues asparagine 354 and isoleucine 372 of human farnesoid X receptor confer the receptor with high sensitivity to chenodeoxycholate. | The Journal of biological chemistry 20020719 |
| Chenodeoxycholic acid and deoxycholic acid inhibit 11 beta-hydroxysteroid dehydrogenase type 2 and cause cortisol-induced transcriptional activation of the mineralocorticoid receptor. | The Journal of biological chemistry 20020719 |
| Fibrates suppress chenodeoxycholic acid-induced RANTES expression through inhibition of NF-kappaB activation. | European journal of pharmacology 20020712 |
| Participation of two members of the very long-chain acyl-CoA synthetase family in bile acid synthesis and recycling. | The Journal of biological chemistry 20020705 |
| On the mechanism of bile acid inhibition of rat sterol 12alpha-hydroxylase gene (CYP8B1) transcription: roles of alpha-fetoprotein transcription factor and hepatocyte nuclear factor 4alpha. | Biochimica et biophysica acta 20020613 |
| A prospective study of serum bile acid concentrations and colorectal cancer risk in post-menopausal women on the island of Guernsey. | British journal of cancer 20020605 |
| Human organic anion transporting polypeptide 8 promoter is transactivated by the farnesoid X receptor/bile acid receptor. | Gastroenterology 20020601 |
| Postprandial changes in serum unconjugated bile acid concentrations in healthy beagles. | American journal of veterinary research 20020601 |
| Effect of colestimide on absorption of unconjugated bile acids in the rat jejunum. | Journal of gastroenterology and hepatology 20020601 |
| A natural product that lowers cholesterol as an antagonist ligand for FXR. | Science (New York, N.Y.) 20020531 |
| Generation of multiple farnesoid-X-receptor isoforms through the use of alternative promoters. | Gene 20020515 |
| A novel primary bile acid in the Shoebill stork and herons and its phylogenetic significance. | Journal of lipid research 20020501 |
| Relationship between asymptomatic hypercholanaemia of pregnancy and progesterone metabolism. | Clinical science (London, England : 1979) 20020501 |
| Immunosuppressive effect of chenodeoxycholic acid on natural killer cell activity in patients with biliary atresia and hepatitis C virus-related liver cirrhosis. | Digestive diseases and sciences 20020501 |
| Disruption of mitochondrial calcium homeostasis after chronic alpha-naphthylisothiocyanate administration: relevance for cholestasis. | Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20020501 |
| Characterization of cloned mouse Na+/taurocholate cotransporting polypeptide by transient expression in COS-7 cells. | Bioscience, biotechnology, and biochemistry 20020501 |
| Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes. | Hepatology (Baltimore, Md.) 20020401 |
| Cerebrotendinous xanthomatosis: a rare disease with diverse manifestations. | Archives of neurology 20020401 |
| [Treatment of cholestatic liver diseases]. | Medizinische Klinik (Munich, Germany : 1983) 20020315 |
| The proximal colonic motor response to rectal mechanical and chemical stimulation. | American journal of physiology. Gastrointestinal and liver physiology 20020301 |
| Characterization of rat liver bile acid acyl glucuronosyltransferase. | Steroids 20020301 |
| Unconjugated bile acids modulate adult and neonatal neutrophil chemotaxis induced in vitro by N-formyl-met-leu-phe-peptide. | Pediatric research 20020301 |
| Farnesoid X receptor and bile salts are involved in transcriptional regulation of the gene encoding the human bile salt export pump. | Hepatology (Baltimore, Md.) 20020301 |
| The UDCA dosage deficit: a fate shared with CDCA. | European journal of gastroenterology & hepatology 20020301 |
| Two novel mutations in the sterol 27-hydroxylase gene causing cerebrotendinous xanthomatosis. | Clinical genetics 20020301 |
| Interactions of combined bile acids on hepatocyte viability: cytoprotection or synergism. | Toxicology letters 20020207 |
| Use of ursodeoxycholic acid in patients with liver disease. | Current gastroenterology reports 20020201 |
| MALDI-TOF-MS analysis of droplets prepared in an electrodynamic balance: 'wall-less' sample preparation. | Analytical chemistry 20020201 |
| Guest-responsive fluorescence variations of gamma-cyclodextrins labeled with hetero-functionalized pyrene and tosyl moieties. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20020201 |
| Conversion of 7 alpha-hydroxycholesterol to bile acid in human subjects: is there an alternate pathway favoring cholic acid synthesis? | The Journal of laboratory and clinical medicine 20020201 |
| Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor. | The Journal of biological chemistry 20020125 |
| Induction of cyclooxygenase-2 by tumor promoters in transformed and cytochrome P450 2E1-expressing hepatocytes. | Carcinogenesis 20020101 |
| Bile salts modulate chronic ethanol-induced hepatotoxicity. | Alcohol and alcoholism (Oxford, Oxfordshire) 20020101 |
| Demonstration of a direct stimulatory effect of bile salts on rat colonic epithelial cell proliferation. | Scandinavian journal of gastroenterology 20020101 |
| Effects of bile acids on base hydroxylation in a model of human colonic mucosal DNA. | Cancer detection and prevention 20020101 |
| Use of dominant negative nuclear receptors to study xenobiotic-inducible gene expression in primary cultured hepatocytes. | Journal of pharmacological and toxicological methods 20020101 |
| Enhanced expression of the human multidrug resistance protein 3 by bile salt in human enterocytes. A transcriptional control of a plausible bile acid transporter. | The Journal of biological chemistry 20011214 |
| Antagonism of the actions of peroxisome proliferator-activated receptor-alpha by bile acids. | The Journal of biological chemistry 20011214 |
| Duodenal reflux induces cyclooxygenase-2 in the esophageal mucosa of rats: evidence for involvement of bile acids. | Gastroenterology 20011201 |
| Effect of bile acids on absorption of nitrendipine in healthy subjects. | British journal of clinical pharmacology 20011201 |
| Inducible microsomal prostaglandin E synthase is overexpressed in colorectal adenomas and cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20011201 |
| Anti-inflammatory effects of 5-aminosalicylic acid conjugates with chenodeoxycholic acid and ursodeoxycholic acid on carrageenan-induced colitis in guinea-pigs. | The Journal of pharmacy and pharmacology 20011201 |
| Predominance of human versus rat phenotype in the metabolic pathways for bile acid synthesis by hybrid WIF-B9 cells. | Biochimica et biophysica acta 20011130 |
| Bile acids regulate RANTES gene expression through its cognate NF-kappaB binding sites. | Biochemical and biophysical research communications 20011116 |
| Cerebrotendinous xanthomatosis. | Neurology 20011113 |
| Transcriptional regulation of the human sterol 12alpha-hydroxylase gene (CYP8B1): roles of heaptocyte nuclear factor 4alpha in mediating bile acid repression. | The Journal of biological chemistry 20011109 |
| Reduced activity of 11 beta-hydroxysteroid dehydrogenase in patients with cholestasis. | The Journal of clinical investigation 20011101 |
| Green tea upregulates the low-density lipoprotein receptor through the sterol-regulated element binding Protein in HepG2 liver cells. | Journal of agricultural and food chemistry 20011101 |
| Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450. | The Journal of biological chemistry 20011019 |
| Functional analysis of the transcriptional activity of the mouse phospholipid transfer protein gene. | Biochemical and biophysical research communications 20011005 |
| Effects of bile acids on the humoral immune response: a mechanistic approach. | Life sciences 20011005 |
| Farnesoid X-activated receptor induces apolipoprotein C-II transcription: a molecular mechanism linking plasma triglyceride levels to bile acids. | Molecular endocrinology (Baltimore, Md.) 20011001 |
| Acute effects of dietary fat composition on postprandial plasma bile acid and cholecystokinin concentrations in healthy premenopausal women. | The British journal of nutrition 20011001 |
| 3beta-hydroxy-delta5 -C27-steroid dehydrogenase deficiency: diagnosis and treatment. | Journal of paediatrics and child health 20011001 |
| Cerebrotendinous xanthomatosis: 11-year treatment with chenodeoxycholic acid in five patients. An electrophysiological study. | Journal of the neurological sciences 20010915 |
| Nuclear receptor-mediated repression of human cholesterol 7alpha-hydroxylase gene transcription by bile acids. | Journal of lipid research 20010901 |
| Biliary excretion of tauroursodeoxycholate-3-sulfate in the rat. | Steroids 20010901 |
| [Cerebrotendinous xanthomatosis]. | Nederlands tijdschrift voor geneeskunde 20010901 |
| External biliary drainage plus bile acid feeding is not equal to internal drainage in preserving the cellular immunity following prolonged obstructive jaundice. | Digestive diseases and sciences 20010901 |
| Effect of bile acids on formation of azoxymethane-induced aberrant crypt foci in colostomized F344 rat colon. | Cancer letters 20010828 |
| The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel mechanism of feedback regulation of bile acid synthesis mediated by nuclear receptors. | The Journal of biological chemistry 20010817 |
| Cerebrotendinous xanthomatosis. | Journal of the American Academy of Dermatology 20010801 |
| Cerebrotendinous xanthomatosis presenting as 'chologenic diarrhoea'. | Acta paediatrica (Oslo, Norway : 1992) 20010701 |
| Protective effect of carvedilol on chenodeoxycholate induction of the permeability transition pore. | Biochemical pharmacology 20010601 |
| Bile acid hydrophobicity is correlated with induction of apoptosis and/or growth arrest in HCT116 cells. | The Biochemical journal 20010601 |
| Expression of sterol 12alpha-hydroxylase alters bile acid pool composition in primary rat hepatocytes and in vivo. | Gastroenterology 20010601 |
| Effect of bile salts on colonic mucus secretion in isolated vascularly perfused rat colon. | Digestive diseases and sciences 20010601 |
| Apoptotic activity of novel bile acid derivatives in human leukemic T cells through the activation of caspases. | International journal of oncology 20010501 |
| Effects of treatment with deoxycholic acid and chenodeoxycholic acid on the hepatic synthesis of cholesterol and bile acids in healthy subjects. | Hepatology (Baltimore, Md.) 20010501 |
| Synthetic bile acid derivatives induce nonapoptotic death of human retinal pigment epithelial cells. | Current eye research 20010501 |
| Enhancement of endothelial nitric oxide production by chenodeoxycholic acids in patients with hepatobiliary diseases. | Japanese heart journal 20010501 |
| Effects of bile salts and aliphatic ionic surfactants on human lymphocyte proliferation. | European journal of clinical investigation 20010401 |
| Successful combination therapy--flunarizine, pentoxifylline, and cholestyramine--for spur cell anemia. | International journal of hematology 20010401 |
| LUV's lipid composition modulates diffusion of bile acids. | Chemistry and physics of lipids 20010401 |
| Cloning and expression of a pig liver taurochenodeoxycholic acid 6alpha-hydroxylase (CYP4A21): a novel member of the CYP4A subfamily. | The Journal of biological chemistry 20010330 |
| Chenodeoxycholic treatment of cerebrotendinous xanthomatosis. | Neurology 20010313 |
| Ursodeoxycholic acid administration in patients with cholestasis of pregnancy: effects on primary bile acids in babies and mothers. | Hepatology (Baltimore, Md.) 20010301 |
| High-performance liquid chromatographic determination of ursodeoxycholic acid after solid phase extraction of blood serum and detection-oriented derivatization. | Journal of pharmaceutical and biomedical analysis 20010301 |
| The nuclear receptors FXR and LXRalpha: potential targets for the development of drugs affecting lipid metabolism and neoplastic diseases. | Current pharmaceutical design 20010301 |
| Hypocholesterolemic effect of bile acid sulfonate analogs in hamsters. | Biological & pharmaceutical bulletin 20010301 |
| Bilirubin-induced apoptosis in cultured rat neural cells is aggravated by chenodeoxycholic acid but prevented by ursodeoxycholic acid. | Journal of hepatology 20010301 |
| [3 beta-Hydroxysteroid-delta 5-oxidoreductase/isomerase deficiency]. | Nihon rinsho. Japanese journal of clinical medicine 20010301 |
| [3-oxo-delta 4-steroid 5 beta-reductase deficiency]. | Nihon rinsho. Japanese journal of clinical medicine 20010301 |
| [Cerebrotendinous xanthomatosis]. | Nihon rinsho. Japanese journal of clinical medicine 20010301 |
| [Other antihyperlipidemic drugs with novel mechanism]. | Nihon rinsho. Japanese journal of clinical medicine 20010301 |
| Novel bile acid derivatives induce apoptosis via a p53-independent pathway in human breast carcinoma cells. | Cancer letters 20010210 |
| Colonic luminal contents induce cyclooxygenase 2 transcription in human colon carcinoma cells. | Gastroenterology 20010201 |
| Differences in hepatic levels of intermediates in bile acid biosynthesis between Cyp27(-/-) mice and CTX. | Journal of lipid research 20010201 |
| Chenodeoxycholate is a potent inducer of the permeability transition pore in rat liver mitochondria. | Bioscience reports 20010201 |
| Magnetic resonance imaging and spectroscopic changes in brains of patients with cerebrotendinous xanthomatosis. | Brain : a journal of neurology 20010101 |
| Ursodeoxycholic acid alone or with chenodeoxycholic acid for dissolution of cholesterol gallstones: a randomized multicentre trial. The British-Italian Gallstone Study group. | Alimentary pharmacology & therapeutics 20010101 |
| Determination of bile acids in biological fluids by liquid chromatography-electrospray tandem mass spectrometry. | Journal of lipid research 20010101 |
| [Advances in the diagnosis and treatment of cholelithiasis]. | Terapevticheskii arkhiv 20010101 |
| Cerebrotendinous xanthomatosis in three siblings from a Chinese family. | Singapore medical journal 20010101 |
| Enzyme immunoassay for conjugated 7alpha-hydroxy-3-oxo-4-cholenoic acid in human urine. | Journal of immunoassay & immunochemistry 20010101 |
| Suppression of renal disease and mortality in the female NZB x NZW F1 mouse model of systemic lupus erythematosus (SLE) by chenodeoxycholic acid. | Lupus 20010101 |
| Differential modulation of cellular death and survival pathways by conjugated bile acids. | BMC biochemistry 20010101 |
| Extracorporeal shock wave lithotripsy of gallstones with oral dissolution. Results in course of ten years in Czech Republic in correlation to indication criteria. | Sbornik lekarsky 20010101 |
| Characterization of chenodeoxycholic acid as an endogenous antagonist of the G-coupled formyl peptide receptors. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20001201 |
| Identification of a chemical tool for the orphan nuclear receptor FXR. | Journal of medicinal chemistry 20000810 |
| In the search for specific inhibitors of human 11beta-hydroxysteroid-dehydrogenases (11beta-HSDs): chenodeoxycholic acid selectively inhibits 11beta-HSD-I. | European journal of endocrinology 20000201 |
| Identification of a nuclear receptor for bile acids. | Science (New York, N.Y.) 19990521 |
| Bile acids: natural ligands for an orphan nuclear receptor. | Science (New York, N.Y.) 19990521 |
| Endogenous bile acids are ligands for the nuclear receptor FXR/BAR. | Molecular cell 19990501 |
| Differential effects of 17alpha-ethinylestradiol on the neutral and acidic pathways of bile salt synthesis in the rat. | Journal of lipid research 19990101 |
| Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter. | The American journal of physiology 19980101 |
| Triterpenes as potential dimerization inhibitors of HIV-1 protease. | Biochemical and biophysical research communications 19961014 |
| Bile acids produce a generalized reduction of the catalytic activity of cytochromes P450 and other hepatic microsomal enzymes in vitro: relevance to drug metabolism in experimental cholestasis. | Journal of gastroenterology and hepatology 19960901 |
| Induction of the transcription factor AP-1 in cultured human colon adenocarcinoma cells following exposure to bile acids. | Carcinogenesis 19960301 |
| Cyclosporin A-mediated cholestasis in patients with chronic hepatitis after heart transplantation. | European journal of gastroenterology & hepatology 19960301 |
| Relationship of human liver dihydrodiol dehydrogenases to hepatic bile-acid-binding protein and an oxidoreductase of human colon cells. | The Biochemical journal 19960115 |
| Suppression of sterol 27-hydroxylase mRNA and transcriptional activity by bile acids in cultured rat hepatocytes. | The Biochemical journal 19950115 |
| Ursodeoxycholic acid in the Ursidae: biliary bile acids of bears, pandas, and related carnivores. | Journal of lipid research 19931101 |
| cDNA cloning and expression of the human hepatic bile acid-binding protein. A member of the monomeric reductase gene family. | The Journal of biological chemistry 19930515 |
| Oral and contact dissolution of gallstones. | American journal of surgery 19930401 |
| Promotion of hepatocellular foci in female rats by chenodeoxycholic acid. | Carcinogenesis 19910101 |
| Benign recurrent intrahepatic cholestasis: altered bile acid metabolism. | Gastroenterology 19890801 |
| Selective activity of several cholic acid derivatives against human immunodeficiency virus replication in vitro. | Journal of acquired immune deficiency syndromes 19890101 |
| [Promoting effect of bile acids on gastric carcinogenesis induced by MNNG in rats]. | Nihon Geka Gakkai zasshi 19890101 |
| [Effect of bile and bile acids on monoamine oxidase and acetylcholinesterase activity in the jejunum of rabbits, guinea pigs and swine]. | Polskie archiwum weterynaryjne 19870101 |
| Evidence for an ordered reaction mechanism for bile salt: 3'phosphoadenosine-5'-phosphosulfate: sulfotransferase from rhesus monkey liver that catalyzes the sulfation of the hepatotoxin glycolithocholate. | Journal of lipid research 19861101 |
| Inhibition of hepatic and extrahepatic glutathione S-transferases by primary and secondary bile acids. | The Biochemical journal 19860115 |
| Comparative efficacy and side effects of ursodeoxycholic and chenodeoxycholic acids in dissolving gallstones. A double-blind controlled study. | Gastroenterology 19831201 |
| Early morphologic and enzymatic changes in livers of rats treated with chenodeoxycholic and ursodeoxycholic acids. | Hepatology (Baltimore, Md.) 19830101 |
| Serum bile acid levels in intrahepatic cholestasis of pregnancy during treatment with phenobarbital or cholestyramine. | European journal of obstetrics, gynecology, and reproductive biology 19821201 |
| Carcinoma of the gall-bladder in a patient on long-term chenodeoxycholic acid therapy. | Clinical oncology 19810901 |
| Lack of response to chenodeoxycholic acid in obese and non-obese patients. Role of cholesterol synthesis and possible response to ursodeoxycholic acid. | Gut 19801201 |
| [Effect of cholestyramine and chenodesoxycholic acid on liver cirrhosis. An experimental study in rats]. | Zeitschrift fur experimentelle Chirurgie 19800401 |
| Hepatic toxicity in the rhesus monkey treated with chenodeoxycholic acid for 6 months: biochemical and ultrastructural studies. | Gastroenterology 19760101 |
| Effects of clofibrate in primary biliary cirrhosis hypercholesterolemia and gallstones. | Gastroenterology 19751001 |
| Measurement of bile acid synthesis by 14CO2: the metabolism of propionyl CoA. | Steroids 19751001 |
| Toxicity of chenodeoxycholic acid in the rhesus monkey. | Gastroenterology 19750801 |
| Toxicity of chenodeoxycholic acid in the nonhuman primate. | Surgery 19750601 |
| Medical treatment of gallstones. | Southern medical journal 19750101 |
| [Effects of diet on bile secretion]. | Acta medica Austriaca 19750101 |
| Farnesoid X receptor protects liver cells from apoptosis induced by serum deprivation in vitro and fasting in vivo. | Molecular endocrinology (Baltimore, Md.) |
| Bile acids down-regulate caveolin-1 in esophageal epithelial cells through sterol responsive element-binding protein. | Molecular endocrinology (Baltimore, Md.) |