Home Aldehydes 2-Thiophenecarboxaldehyde

2-Thiophenecarboxaldehyde

CAS No.:
98-03-3
Catalog Number:
AG0039AP
Molecular Formula:
C5H4OS
Molecular Weight:
112.1497
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
25g
98%
In Stock USA
United States
$25
- +
100g
98%
In Stock USA
United States
$63
- +
250g
98%(GC)
In Stock USA
United States
$104
- +
Product Description
Catalog Number:
AG0039AP
Chemical Name:
2-Thiophenecarboxaldehyde
CAS Number:
98-03-3
Molecular Formula:
C5H4OS
Molecular Weight:
112.1497
MDL Number:
MFCD00005429
IUPAC Name:
thiophene-2-carbaldehyde
InChI:
InChI=1S/C5H4OS/c6-4-5-2-1-3-7-5/h1-4H
InChI Key:
CNUDBTRUORMMPA-UHFFFAOYSA-N
SMILES:
O=Cc1cccs1
EC Number:
202-629-8
UNII:
IW05BB9XBM
NSC Number:
2162
Properties
Complexity:
72.5  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
111.998g/mol
Formal Charge:
0
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
112.146g/mol
Monoisotopic Mass:
111.998g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
45.3A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1  
Literature
Title Journal
α,α'-N-Boc-substituted bi- and terthiophenes: fluorescent precursors for functional materials. The Journal of organic chemistry 20120615
3',6'-Bis(ethyl-amino)-2',7'-dimethyl-2-{2-(E)-[(thio-phen-2-yl)methyl-idene-amino]-eth-yl}spiro-[isoindoline-1,9'-xanthen]-3-one methanol monosolvate. Acta crystallographica. Section E, Structure reports online 20120501
Synthesis, characterization and biodistribution of novel amine thiophene ⁹⁹mTc labeled complex. Pakistan journal of pharmaceutical sciences 20120401
Benzyl 2-methyl-3-[(E)-(thio-phen-2-yl)methyl-idene]dithio-carbazate. Acta crystallographica. Section E, Structure reports online 20120401
(4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-di-yl]bis-[N-(thio-phen-2-yl-methyl-idene)methanamine. Acta crystallographica. Section E, Structure reports online 20120201
Synthesis by ring-closing metathesis and cytotoxic evaluation of novel thienylmacrolactones. Scientia pharmaceutica 20120101
A comparative study of homolytic reactions of fullerenes with aldehydes in a mass spectrometer under electron impact and in solution under UV irradiation. European journal of mass spectrometry (Chichester, England) 20120101
6-Bromo-2-[(E)-thio-phen-2-yl-methyl-idene]-2,3,4,9-tetra-hydro-1H-carbazol-1-one. Acta crystallographica. Section E, Structure reports online 20111201
Synthesis, spectroscopic and electrochemical studies of N,N-bis[(E)-2-thienylmethylidene]-1,8-naphthalenediamine and its Cu(II) complex: DNA cleavage and generation of superoxide anion. Journal of photochemistry and photobiology. B, Biology 20110902
Synthesis, spectral, antimicrobial and antitumor assessment of Schiff base derived from 2-aminobenzothiazole and its transition metal complexes. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110901
Synthesis, spectroscopic studies and crystal structure of the Schiff base ligand L derived from condensation of 2-thiophenecarboxaldehyde and 3,3'-diaminobenzidine and its complexes with Co(II), Ni(II), Cu(II), Cd(II) and Hg(II): Comparative DNA binding studies of L and its Co(II), Ni(II) and Cu(II) complexes. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110901
(E)-2-Methyl-5-(thiophen-2-ylmethyl-idene)cyclopentan-1-one. Acta crystallographica. Section E, Structure reports online 20110901
(2E)-1-(2,4-Dimethyl-quinolin-3-yl)-3-(thio-phen-2-yl)prop-2-en-1-one. Acta crystallographica. Section E, Structure reports online 20110901
2-Oxo-4-(thio-phen-2-yl)-1,2,5,6-tetra-hydro-benzo[h]quinoline-3-carbonitrile. Acta crystallographica. Section E, Structure reports online 20110901
Use of the hydantoin isostere to produce inhibitors showing selectivity toward the vesicular glutamate transporter versus the obligate exchange transporter system x(c)(-). Bioorganic & medicinal chemistry letters 20110715
2-(Naphthalen-1-yl)-4-(thio-phen-2-yl-methyl-idene)-1,3-oxazol-5(4H)-one. Acta crystallographica. Section E, Structure reports online 20110601
Effect of substituent of β-diketones on the synergistic extraction of lanthanoids with linear polyether. Talanta 20110530
Third generation fluoroquinolones antibacterial drug based mixed-ligand Cu(II) complexes: structure, antibacterial activity, superoxide dismutase activity and DNA-interaction approach. Journal of enzyme inhibition and medicinal chemistry 20110401
N'-[1-(2,4-Dioxo-3,4-dihydro-2H-1-benzopyran-3-yl-idene)eth-yl]thiophene-2-carbo-hydrazide. Acta crystallographica. Section E, Structure reports online 20110401
(E)-2-(2-Nitro-prop-1-en-yl)thio-phene. Acta crystallographica. Section E, Structure reports online 20110401
2-(2,2-Dibromo-ethen-yl)thio-phene. Acta crystallographica. Section E, Structure reports online 20110201
P=C-N-heterocycles: synthesis of biaryl-type 1,3-benzazaphospholes with ortho-substituted phenyl or 2-heteroaryl groups. Dalton transactions (Cambridge, England : 2003) 20110107
Copper and its complexes in medicine: a biochemical approach. Molecular biology international 20110101
A nanostructured piezoelectric immunosensor for detection of human cardiac troponin T. Sensors (Basel, Switzerland) 20110101
Elevation of antidermatophytic action of mefenamic acid by cobalt ions. Indian journal of pharmacology 20101201
6-Amino-5-(1-amino-2,2-dicyano-vin-yl)-3,3a,4,5-tetra-hydro-2H-indene-4-spiro-1'-cyclo-pentane-3a,7-dicarbonitrile-thio-phene-2-carbaldehyde (1/0.5). Acta crystallographica. Section E, Structure reports online 20101001
Benzoyl radicals from (hetero)aromatic aldehydes. Decatungstate photocatalyzed synthesis of substituted aromatic ketones. Organic & biomolecular chemistry 20100921
Synthesis of chiral macrocyclic or linear pyridine carboxamides from pyridine-2,6-dicarbonyl dichloride as antimicrobial agents. Molecules (Basel, Switzerland) 20100920
(E)-N'-(2-Thienyl-methyl-idene)-p-toluene-sulfono-hydrazide. Acta crystallographica. Section E, Structure reports online 20100901
(E)-N'-(9-Anthryl-methyl-idene)-p-toluene-sulfono-hydrazide. Acta crystallographica. Section E, Structure reports online 20100901
Cyclometalated Ru complexes of type [Ru(II)(N--N)(2)(C--N)](z): physicochemical response to substituents installed on the anionic ligand. Inorganic chemistry 20100607
2-(3,4-Dimethyl-5,5-dioxo-2H,4H-pyrazolo[4,3-c][1,2]benzothia-zin-2-yl)-N'-(2-thienylmethyl-idene)acetohydrazide. Acta crystallographica. Section E, Structure reports online 20100601
Adsorption and separation of reactive aromatic isomers and generation and stabilization of their radicals within cadmium(II)-triazole metal-organic confined space in a single-crystal-to-single-crystal fashion. Journal of the American Chemical Society 20100526
1-Methyl-2-[(E)-2-(2-thien-yl)ethen-yl]quinolinium 4-bromo-benzene-sulfonate. Acta crystallographica. Section E, Structure reports online 20100501
Synthesis and characterization of a class of donor-acceptor conjugated molecules: experiments and theoretical calculations. The journal of physical chemistry. A 20100408
(E)-3-(2,3,4,5,6-Penta-fluoro-styr-yl)thio-phene. Acta crystallographica. Section E, Structure reports online 20100401
Screening of biological activities of a series of chalcone derivatives against human pathogenic microorganisms. Chemistry & biodiversity 20100201
Use of empirical correlations to determine solvent effects in the solvolysis of S-methyl chlorothioformate. International journal of molecular sciences 20100101
4-(2-Thienylmethyl-eneamino)benzoic acid. Acta crystallographica. Section E, Structure reports online 20091101
N-(2-Thienylmethyl-ene)naphthalen-1-amine. Acta crystallographica. Section E, Structure reports online 20091101
Thienylhalomethylketones: Irreversible glycogen synthase kinase 3 inhibitors as useful pharmacological tools. Bioorganic & medicinal chemistry 20091001
1-Benzyl-3,5-bis-(2-thienylmethyl-ene)-4-piperidone. Acta crystallographica. Section E, Structure reports online 20091001
N,N-Bis(2-thienylmethyl-ene)cyclo-hexane-1,4-diamine. Acta crystallographica. Section E, Structure reports online 20091001
(2E)-1-(4-Amino-phen-yl)-3-(2-thien-yl)prop-2-en-1-one ethanol hemisolvate. Acta crystallographica. Section E, Structure reports online 20091001
N,N'-Bis(2-thienylmethyl-ene)benzene-1,4-diamine. Acta crystallographica. Section E, Structure reports online 20090901
2,6-Diphenyl-4-(2-thien-yl)-1,4-dihydro-pyridine-3,5-dicarbonitrile. Acta crystallographica. Section E, Structure reports online 20090901
N,N'-Bis[(E)-2-thienylmethyl-ene]-4,4'-oxydianiline. Acta crystallographica. Section E, Structure reports online 20090901
(S)-(+)-1-(1-Naphth-yl)-1-(2-thienylmethyl-ene)ethyl-amine. Acta crystallographica. Section E, Structure reports online 20090701
(E)-5-Phenyl-N-(2-thienylmethyl-ene)-1,3,4-thia-diazole-2-amine. Acta crystallographica. Section E, Structure reports online 20090701
N-(2-Thienylmethyl-ene)-2-(2-{[2-(2-thienylmethyl-eneamino)phen-yl]sulfan-yl}ethyl-sulfan-yl)aniline. Acta crystallographica. Section E, Structure reports online 20090701
Determination of trace heavy metals in soil and sediments by atomic spectrometry following preconcentration with Schiff bases on Amberlite XAD-4. Journal of hazardous materials 20090615
1,1'-(2-Thienylmethylene)di-2-naphthol ethyl acetate solvate. Acta crystallographica. Section E, Structure reports online 20090601
(±)-trans-6,7-Dimeth-oxy-1-oxo-3-(2-thien-yl)isochroman-4-carboxylic acid. Acta crystallographica. Section E, Structure reports online 20090601
Immunomodulatory and anticancer activities of some novel 2-substituted-6-bromo-3-methylthiazolo[3,2-a]benzimidazole derivatives. Archiv der Pharmazie 20090401
(4S,5S)-2-(2-Thien-yl)-1,3-dioxolane-4,5-dicarboxamide. Acta crystallographica. Section E, Structure reports online 20090401
A combined experimental and theoretical study of the polar [3 + 2] cycloaddition of electrophilically activated carbonyl ylides with aldehydes and imines. The Journal of organic chemistry 20090306
Corrrelation of the specific rates of solvolysis of ethyl fluoroformate using the extended Grunwald-Winstein equation. International journal of molecular sciences 20090301
(2,6-Diisopropyl-phen-yl)(2-thienylmethyl-ene)amine. Acta crystallographica. Section E, Structure reports online 20090301
Synthesis and pharmacological evaluation of schiff bases of 4-(2-aminophenyl)-morpholines. Indian journal of pharmaceutical sciences 20090101
Evaluation of anti-inflammatory and antioxidant activities of copper (II) Schiff mono-base and copper(II) Schiff base coordination compounds of dien with heterocyclic aldehydes and 2-amino-5-methyl-thiazole. Journal of enzyme inhibition and medicinal chemistry 20081201
Thio-phene-2-carbaldehyde 2,4-dinitro-phenyl-hydrazone. Acta crystallographica. Section E, Structure reports online 20081201
1,5-Bis(4-chloro-phen-yl)-3-(2-thien-yl)pentane-1,5-dione. Acta crystallographica. Section E, Structure reports online 20081201
DNA interaction studies and evaluation of biological activity of homo- and hetero-trihalide mononuclear Cu(II) Schiff base complexes. Quantitative structure-activity relationships. Journal of inorganic biochemistry 20080901
(E,E)-1,5-Di-2-thienylpenta-1,4-dien-3-one. Acta crystallographica. Section E, Structure reports online 20080901
Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries. Natural product reports 20080801
1-Methyl-2-[(E)-2-(2-thien-yl)ethen-yl]quinolinium iodide. Acta crystallographica. Section E, Structure reports online 20080801
Synthesis and anti-breast cancer activities of substituted quinolines. Bioorganic & medicinal chemistry letters 20080601
(E)-2-[2-(2-Thien-yl)vin-yl]-1H-1,3-benzimidazole. Acta crystallographica. Section E, Structure reports online 20080601
2,4-Bis(4-chloro-benzo-yl)-1-(4-chloro-phen-yl)-3,5-di-2-thienylcyclo-hexa-nol methanol hemisolvate. Acta crystallographica. Section E, Structure reports online 20080501
Ethyl 4-hydroxy-methyl-2-methyl-pyridine-5-carboxyl-ate. Acta crystallographica. Section E, Structure reports online 20080501
Novel 3-aroylpyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides 8-substituted, ligands at GABAA/benzodiazepine receptor complex: synthesis, pharmacological and molecular modeling studies. Bioorganic & medicinal chemistry 20080415
1-Methyl-4-[(E)-2-(2-thien-yl)ethen-yl]pyridinium 4-chloro-benzene-sulfonate. Acta crystallographica. Section E, Structure reports online 20080301
Synthesis, characterization, and in vitro cytotoxic activities of benzaldehyde thiosemicarbazone derivatives and their palladium (II) and platinum (II) complexes against various human tumor cell lines. Bioinorganic chemistry and applications 20080101
2-(9H-Fluoren-9-ylidenemeth-yl)thio-phene. Acta crystallographica. Section E, Structure reports online 20080101
(E)-5-(2-Thienylmethyl-eneamino)quinolin-8-ol. Acta crystallographica. Section E, Structure reports online 20080101
[Ten years of work of Lions Croatian Eye Bank]. Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti 20071201
Mononuclear metal complexes of organic carboxylic acid derivatives: synthesis, spectroscopic characterization, thermal investigation and antimicrobial activity. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070501
Design, synthesis, and evaluation of inhibitors for severe acute respiratory syndrome 3C-like protease based on phthalhydrazide ketones or heteroaromatic esters. Journal of medicinal chemistry 20070419
Synthesis, spectroscopic, thermal and antimicrobial studies of some novel metal complexes of Schiff base derived from [N1-(4-methoxy-1,2,5-thiadiazol-3-yl)sulfanilamide] and 2-thiophene carboxaldehyde. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070401
Application of thiophene-2-carbaldehyde-modified mesoporous silica as a new sorbent for separation and preconcentration of palladium prior to inductively coupled plasma atomic emission spectrometric determination. Talanta 20070315
Complexes of 2-thiophenecarbonyl and isonicotinoyl hydrazones of 3-(N-methyl)isatin. A study of their antimicrobial activity. Journal of inorganic biochemistry 20070101
Theoretical study of the syn and anti thiophene-2-aldehyde conformers using density functional theory and normal coordinate analysis. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20061101
Synthesis of heteroaryl imines: theoretical and experimental approach to the determination of the configuration of C=N double bond. The Journal of organic chemistry 20060915
Cyclooctadiene Ru(II) complexes of thiophene-2-carboxaldehyde-derived thiosemicarbazones: synthesis, characterization and antiamoebic activity. European journal of medicinal chemistry 20060501
In vitro antibacterial, antifungal & cytotoxic activity of some isonicotinoylhydrazide Schiff's bases and their cobalt (II), copper (II), nickel (II) and zinc (II) complexes. Journal of enzyme inhibition and medicinal chemistry 20060201
Synthesis, characterization and biological activity of some transition metals with Schiff base derived from 2-thiophene carboxaldehyde and aminobenzoic acid. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20051201
Copper(II) complexes with substituted thiosemicarbazones of thiophene-2-carboxaldehyde: synthesis, characterization and antiamoebic activity against E. histolytica. European journal of medicinal chemistry 20051201
In vivo anticancer, anti-inflammatory, and toxicity studies of mixed-ligand Cu(II) complexes of dien and its Schiff dibases with heterocyclic aldehydes and 2-amino-2-thiazoline. Crystal structure of [Cu(dien)(Br)(2a-2tzn)](Br)(H(2)O). Journal of inorganic biochemistry 20051101
[Method of suturing of the soft tissues wound]. Klinichna khirurhiia 20050901
The structure and conformations of 2-thiophenecarboxaldehyde obtained from partially averaged dipolar couplings. Chemphyschem : a European journal of chemical physics and physical chemistry 20050812
Evidence for the formation of adducts and S-(carboxymethyl)cysteine on reaction of alpha-dicarbonyl compounds with thiol groups on amino acids, peptides, and proteins. Chemical research in toxicology 20050801
Prediction of genotoxicity of chemical compounds by statistical learning methods. Chemical research in toxicology 20050601
A versatile synthesis of pyrazolo[3,4-c]isoquinoline derivatives by reaction of 4-aryl-5-aminopyrazoles with aryl/heteroaryl aldehydes: the effect of the heterocycle on the reaction pathways. Organic & biomolecular chemistry 20050307
The unexpected formation of biologically active Cu(II) Schiff mono-base complexes with 2-thiophene-carboxaldehyde and dipropylenetriamine: crystal and molecular structure of CudptaSCl2. Journal of inorganic biochemistry 20050201
Copper(II) Schiff base coordination compounds of dien with heterocyclic aldehydes and 2-amino-5-methyl-thiazole: synthesis, characterization, antiproliferative and antibacterial studies. Crystal structure of CudienOOCl2. Journal of inorganic biochemistry 20040801
NH2-SEP-PAK cartridges for enrichment of Aromatic Sulfur Compounds from sea water: determination by GC-FID and GC-MS. Annali di chimica 20040101
Synthesis, spectral studies and screening for amoebicidal activity of new palladium(II) complexes derived from thiophene-2-carboxaldehyde thiosemicarbazones. Bioorganic & medicinal chemistry letters 20030224
Reaction of 1,4-phthalazinedione with furfural: formation of the [5,6]benza-3a,7a-diazaindane system via an unusual skeletal rearrangement. Organic letters 20020307
Antibodies directed to drug epitopes to investigate the structure of drug-protein photoadducts. Recognition of a common photobound substructure in tiaprofenic acid/ketoprofen cross-photoreactivity. Chemical research in toxicology 20011101
Synthesis, characterisation and antiamoebic activity of new thiophene-2-carboxaldehyde thiosemicarbazone derivatives and their cyclooctadiene Ru(II) complexes. Bioorganic & medicinal chemistry letters 20011022
Properties