1H-Indol-2-amine
| Title | Journal |
|---|---|
| Mechanistic studies on CymD: a tryptophan reverse N-prenyltransferase. | Biochemistry 20121002 |
| Synthesis and evaluation of indole-containing 3,5-diarylisoxazoles as potential pro-apoptotic antitumour agents. | European journal of medicinal chemistry 20121001 |
| Asymmetric chemoenzymatic synthesis of ramatroban using lipases and oxidoreductases. | The Journal of organic chemistry 20120518 |
| Streptocarbazoles A and B, two novel indolocarbazoles from the marine-derived actinomycete strain Streptomyces sp. FMA. | Organic letters 20120504 |
| Fas/Fas ligand regulation mediates cell death in human Ewing's sarcoma cells treated with melatonin. | British journal of cancer 20120327 |
| Cyclooxygenase-1-selective inhibitors based on the (E)-2'-des-methyl-sulindac sulfide scaffold. | Journal of medicinal chemistry 20120308 |
| Substrate binding and translocation of the serotonin transporter studied by docking and molecular dynamics simulations. | Journal of molecular modeling 20120301 |
| Novel Cβ-Cγ bond cleavages of tryptophan-containing peptide radical cations. | Journal of the American Society for Mass Spectrometry 20120201 |
| Infiltrating cellular pattern in kidney graft biopsies translates into forkhead box protein 3 up-regulation and p16INK4α senescence protein down-regulation in patients treated with belatacept compared to cyclosporin A. | Clinical and experimental immunology 20120201 |
| 7,8-dichloro-1-oxo-β-carbolines as a versatile scaffold for the development of potent and selective kinase inhibitors with unusual binding modes. | Journal of medicinal chemistry 20120112 |
| Brain microdialysis in freely moving animals. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| Molecular characterization of MHC-DRB cDNA in water buffalo (Bubalus bubalis). | Genetics and molecular biology 20120101 |
| Interaction of Rio1 kinase with toyocamycin reveals a conformational switch that controls oligomeric state and catalytic activity. | PloS one 20120101 |
| Three-component tandem reaction involving acid chlorides, terminal alkynes, and 2-aminoindole hydrochlorides: synthesis of α-carboline derivatives in aqueous conditions via regioselective [3 + 3] cyclocondensation. | The Journal of organic chemistry 20111216 |
| Plasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains. | PLoS genetics 20111201 |
| Redox-active bridging ligands based on indigo diimine ('Nindigo') derivatives. | Inorganic chemistry 20111017 |
| Binding site influence on the electronic structure and electron paramagnetic resonance properties of the phyllosemiquinone free radical of photosystem I. | The journal of physical chemistry. B 20110728 |
| Progress in structure based drug design for G protein-coupled receptors. | Journal of medicinal chemistry 20110714 |
| Recognition of the F&H motif by the Lowe syndrome protein OCRL. | Nature structural & molecular biology 20110701 |
| Interaction of the p53 DNA-binding domain with its n-terminal extension modulates the stability of the p53 tetramer. | Journal of molecular biology 20110610 |
| Structure and reaction mechanism in the heme dioxygenases. | Biochemistry 20110412 |
| Solution structure of a repeated unit of the ABA-1 nematode polyprotein allergen of Ascaris reveals a novel fold and two discrete lipid-binding sites. | PLoS neglected tropical diseases 20110401 |
| meso-[5,10,15,20-Tetra-kis(4-cyano-phen-yl)porphyrinato]zinc. | Acta crystallographica. Section E, Structure reports online 20110401 |
| Structure of rhomboid protease in a lipid environment. | Journal of molecular biology 20110325 |
| Specific CLK inhibitors from a novel chemotype for regulation of alternative splicing. | Chemistry & biology 20110128 |
| Melatonin reduces the severity of experimental amoebiasis. | Parasites & vectors 20110101 |
| An optimal method of iron starvation of the obligate intracellular pathogen, Chlamydia trachomatis. | Frontiers in microbiology 20110101 |
| The effect of varying short-chain alkyl substitution on the molar absorptivity and quantum yield of cyanine dyes. | Analytical chemistry insights 20110101 |
| Biosynthetic gene cluster for the cladoniamides, bis-indoles with a rearranged scaffold. | PloS one 20110101 |
| The Aggregation Inhibitor Peptide QBP1 as a Therapeutic Molecule for the Polyglutamine Neurodegenerative Diseases. | Journal of amino acids 20110101 |
| Study of the role of 'gatekeeper' mutations V654A and T670I of c-kit kinase in the interaction with inhibitors by means mixed molecular dynamics/docking approach. | Bioinformation 20110101 |
| Indoleamine 2,3-dioxygenase expression in patients with allergic rhinitis: a case-control study. | Clinical and translational allergy 20110101 |
| The second-shell metal ligands of human arginase affect coordination of the nucleophile and substrate. | Biochemistry 20101214 |
| Selection of evodiamine as a novel topoisomerase I inhibitor by structure-based virtual screening and hit optimization of evodiamine derivatives as antitumor agents. | Journal of medicinal chemistry 20101111 |
| The Structure of the talin head reveals a novel extended conformation of the FERM domain. | Structure (London, England : 1993) 20101013 |
| Melatonin induces pro-apoptotic signaling pathway in human pancreatic carcinoma cells (PANC-1). | Journal of pineal research 20101001 |
| UV-dissipation mechanisms in the eumelanin building block DHICA. | Chemphyschem : a European journal of chemical physics and physical chemistry 20100802 |
| Organometallic indolo[3,2-c]quinolines versus indolo[3,2-d]benzazepines: synthesis, structural and spectroscopic characterization, and biological efficacy. | Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20100801 |
| Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases. | PLoS biology 20100701 |
| Probing the ternary complexes of indoleamine and tryptophan 2,3-dioxygenases by cryoreduction EPR and ENDOR spectroscopy. | Journal of the American Chemical Society 20100421 |
| Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynones. | Journal of the American Chemical Society 20100324 |
| The development of a knowledge base for basic active structures: an example case of dopamine agonists. | Chemistry Central journal 20100101 |
| Halogenated indole alkaloids from marine invertebrates. | Marine drugs 20100101 |
| Iterative structure-based peptide-like inhibitor design against the botulinum neurotoxin serotype A. | PloS one 20100101 |
| A critical tryptophan and Ca2+ in activation and catalysis of TPPI, the enzyme deficient in classic late-infantile neuronal ceroid lipofuscinosis. | PloS one 20100101 |
| IDO-Mediated Tryptophan Degradation in the Pathogenesis of Malignant Tumor Disease. | International journal of tryptophan research : IJTR 20100101 |
| The antinociceptive and anti-inflammatory activities of caulerpin, a bisindole alkaloid isolated from seaweeds of the genus Caulerpa. | Marine drugs 20091201 |
| Marine pyrrolocarbazoles and analogues: synthesis and kinase inhibition. | Marine drugs 20091201 |
| Total synthesis and antiproliferative activity screening of (+/-)-aplicyanins A, B and E and related analogues. | Journal of medicinal chemistry 20091022 |
| Synthesis and biological activities of aminopyrimidyl-indoles structurally related to meridianins. | Bioorganic & medicinal chemistry 20090701 |
| Trp180 of endothelial NOS and Trp56 of bacterial saNOS modulate sigma bonding of the axial cysteine to the heme. | Journal of inorganic biochemistry 20090701 |
| Sleep-promoting action of IIK7, a selective MT2 melatonin receptor agonist in the rat. | Neuroscience letters 20090626 |
| Gold nanoparticles as assisted matrices for the detection of biomolecules in a high-salt solution through laser desorption/ionization mass spectrometry. | Journal of the American Society for Mass Spectrometry 20090501 |
| Development of a novel virtual screening cascade protocol to identify potential trypanothione reductase inhibitors. | Journal of medicinal chemistry 20090326 |
| Structural determinants of species-selective substrate recognition in human and Drosophila serotonin transporters revealed through computational docking studies. | Proteins 20090215 |
| Tetracyclic indole inhibitors of hepatitis C virus NS5B-polymerase. | Bioorganic & medicinal chemistry letters 20090201 |
| Resonance Raman characterization of a stable tryptophan radical in an azurin mutant. | The journal of physical chemistry. B 20090108 |
| Structural basis for substrate specificity in human monomeric carbonyl reductases. | PloS one 20090101 |
| Isothiocyanate NB7M causes selective cytotoxicity, pro-apoptotic signalling and cell-cycle regression in ovarian cancer cells. | British journal of cancer 20081202 |
| Rhabdovirus matrix protein structures reveal a novel mode of self-association. | PLoS pathogens 20081201 |
| Chemical substructures that enrich for biological activity. | Bioinformatics (Oxford, England) 20081101 |
| Mechanism of the efficient tryptophan fluorescence quenching in human gammaD-crystallin studied by time-resolved fluorescence. | Biochemistry 20081007 |
| Thermodynamics of peptide insertion and aggregation in a lipid bilayer. | The journal of physical chemistry. B 20080828 |
| Crystal structure of botulinum neurotoxin type A in complex with the cell surface co-receptor GT1b-insight into the toxin-neuron interaction. | PLoS pathogens 20080801 |
| TrkA kinase inhibitors from a library of modified and isosteric Staurosporine aglycone. | Bioorganic & medicinal chemistry letters 20080615 |
| Unanticipated acyloxymethylation of sumatriptan indole nitrogen atom and its implications in prodrug design. | Archiv der Pharmazie 20080601 |
| A general synthetic entry to the pentacyclic strychnos alkaloid family, using a [4 + 2]-cycloaddition/rearrangement cascade sequence. | The Journal of organic chemistry 20080502 |
| Synthesis, checkpoint kinase 1 inhibitory properties and in vitro antiproliferative activities of new pyrrolocarbazoles. | Bioorganic & medicinal chemistry 20080415 |
| On-line concentration and separation of indolamines, catecholamines, and metanephrines in capillary electrophoresis using high concentration of poly(diallyldimethylammonium chloride). | Analytica chimica acta 20080414 |
| Synthesis and biological evaluation of 1-methyl-2-(3',4',5'-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors. | Journal of medicinal chemistry 20080313 |
| N-Alkoxy derivatization of indole-3-carbinol increases the efficacy of the G1 cell cycle arrest and of I3C-specific regulation of cell cycle gene transcription and activity in human breast cancer cells. | Biochemical pharmacology 20080201 |
| Induction of cytotoxicity, apoptosis and cell cycle arrest by 1-t-butyl carbamoyl, 7-methyl-indole-3-ethyl isothiocyanate (NB7M) in nervous system cancer cells. | Drug design, development and therapy 20080101 |
| New potent indole derivatives as hyaluronidase inhibitors. | Chemical biology & drug design 20071201 |
| Involvement of vagal nerves in the pancreatostimulatory effects of luminal melatonin, or its precursor L-tryptophan. Study in the rats. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20071201 |
| X-ray structure of Cerulean GFP: a tryptophan-based chromophore useful for fluorescence lifetime imaging. | Biochemistry 20070904 |
| Design, synthesis, and evaluation of potential inhibitors of brassinin glucosyltransferase, a phytoalexin detoxifying enzyme from Sclerotinia sclerotiorum. | Bioorganic & medicinal chemistry 20070901 |
| Synthesis and novel fluorescence phenomenon of terbium complex with a new Schiff base ligand derived from condensation of triaminotriethylamine and 3-indolemethanal. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070601 |
| Indium-labeled macrocyclic conjugates of naltrindole: high-affinity radioligands for in vivo studies of peripheral delta opioid receptors. | Journal of medicinal chemistry 20070503 |
| Type III effector activation via nucleotide binding, phosphorylation, and host target interaction. | PLoS pathogens 20070301 |
| Quantitative structure-activity relationship (QSAR) of indoloacetamides as inhibitors of human isoprenylcysteine carboxyl methyltransferase. | Bioorganic & medicinal chemistry letters 20070215 |
| Bis-imide granulatimide analogues as potent Checkpoint 1 kinase inhibitors. | European journal of pharmacology 20070112 |
| Reaction of the indole group with malondialdehyde: application for the derivatization of tryptophan residues in peptides. | Bioconjugate chemistry 20070101 |
| General strategy for the syntheses of corynanthe, tacaman, and oxindole alkaloids. | The Journal of organic chemistry 20060818 |
| Hydrophobic effect and hydrogen bonds account for the improved activity of a complement inhibitor, compstatin. | Journal of medicinal chemistry 20060727 |
| Roles for Arg426 and Trp111 in the modulation of NADH oxidase activity of the catalase-peroxidase KatG from Burkholderia pseudomallei inferred from pH-induced structural changes. | Biochemistry 20060425 |
| Evidence for displacements of the C-helix by CO ligation and DNA binding to CooA revealed by UV resonance Raman spectroscopy. | The Journal of biological chemistry 20060421 |
| Synthesis, antioxidant activity and structure-activity relationships for a new series of 2-(N-acylaminoethyl)indoles with melatonin-like cytoprotective activity. | Journal of pineal research 20060401 |
| Comparative genomics of emerging human ehrlichiosis agents. | PLoS genetics 20060201 |
| N-Nitroso products from the reaction of indoles with Angeli's salt. | Chemical research in toxicology 20060101 |
| Indolyl esters and amides related to indomethacin are selective COX-2 inhibitors. | Bioorganic & medicinal chemistry 20051215 |
| Configurational stability of bisindolylmaleimide cyclophanes: from conformers to the first configurationally stable, atropisomeric bisindolylmaleimides. | Chemistry (Weinheim an der Bergstrasse, Germany) 20051021 |
| Deciphering the late steps in the biosynthesis of the anti-tumour indolocarbazole staurosporine: sugar donor substrate flexibility of the StaG glycosyltransferase. | Molecular microbiology 20051001 |
| On the structural basis of the catalytic mechanism and the regulation of the alpha subunit of tryptophan synthase from Salmonella typhimurium and BX1 from maize, two evolutionarily related enzymes. | Journal of molecular biology 20050923 |
| Conformationally restricted homotryptamines. 2. Indole cyclopropylmethylamines as selective serotonin reuptake inhibitors. | Journal of medicinal chemistry 20050922 |
| Development of an efficient strategy for the synthesis of the ETB receptor antagonist BQ-788 and some related analogues. | Peptides 20050801 |
| Control of competing N-H insertion and Wolff rearrangement in dirhodium(II)-catalyzed reactions of 3-indolyl diazoketoesters. synthesis of a potential precursor to the marine 5-(3-indolyl)oxazole martefragin A. | The Journal of organic chemistry 20050722 |
| Changes in interhelical hydrogen bonding upon rhodopsin activation. | Journal of molecular biology 20050408 |
| Structural characterization of the Ser324Thr variant of the catalase-peroxidase (KatG) from Burkholderia pseudomallei. | Journal of molecular biology 20050107 |
| Effects of melatonin treatment on Leydig cell activity in the testis of the frog Rana esculenta. | Zygote (Cambridge, England) 20041101 |
| Recognition and accommodation at the androgen receptor coactivator binding interface. | PLoS biology 20040901 |
| Crystal structure of the ascorbate peroxidase-salicylhydroxamic acid complex. | Biochemistry 20040713 |
| A new strategy toward indole alkaloids involving an intramolecular cycloaddition/rearrangement cascade. | The Journal of organic chemistry 20040528 |
| Tryptophan recycling is responsible for the interferon-gamma resistance of Chlamydia psittaci GPIC in indoleamine dioxygenase-expressing host cells. | Molecular microbiology 20040501 |
| Intramolecular reactions of 2-indolylacyl radicals: access to 1,2-fused ring indole derivatives. | Organic letters 20040304 |
| Inter-genomic displacement via lateral gene transfer of bacterial trp operons in an overall context of vertical genealogy. | BMC biology 20040101 |
| Synthesis of annulated gamma-carbolines and heteropolycycles by the palladium-catalyzed intramolecular annulation of alkynes. | The Journal of organic chemistry 20030627 |
| Age-associated changes in the monoaminergic innervation of rat lumbosacral spinal cord. | Brain research 20030516 |
| New N-pyridinyl(methyl)-N1-substituted-3-indolepropanamides acting as topical and systemic anti-inflammatory agents. | Journal of enzyme inhibition and medicinal chemistry 20030401 |
| Syntheses and antiproliferative activities of 7-azarebeccamycin analogues bearing one 7-azaindole moiety. | Journal of medicinal chemistry 20030213 |
| Rebeccamycin analogues as anti-cancer agents. | European journal of medicinal chemistry 20030201 |
| Sulfamoyloxy-substituted 2-phenylindoles: antiestrogen-based inhibitors of the steroid sulfatase in human breast cancer cells. | Bioorganic & medicinal chemistry 20021201 |
| Synthesis and biological evaluation of 14-alkoxymorphinans. 17. Highly delta opioid receptor selective 14-alkoxy-substituted indolo- and benzofuromorphinans. | Journal of medicinal chemistry 20021121 |
| Thermolysis of benzannulated enyne-carbodiimides. Application in the synthesis of pyrido[1',2':1,2]pyrimido[4,5-b]indoles and related heteroaromatic compounds. | The Journal of organic chemistry 20021101 |
| Synthesis of annulated gamma-carbolines by palladium-catalyzed intramolecular iminoannulation. | Organic letters 20020905 |
| Synthesis of a psilocin hapten and a protein-hapten conjugate. | The Journal of pharmacy and pharmacology 20020901 |
| Chromaffin cell catecholamine secretion: bisindolylmaleimide compounds exhibit novel and potent antagonist effects at the nicotinic cholinergic receptor in pheochromocytoma cells. | Molecular pharmacology 20020601 |
| Changes in hydrogen bonding and environment of tryptophan residues on helix F of bacteriorhodopsin during the photocycle: a time-resolved ultraviolet resonance Raman study. | Biochemistry 20020521 |
| Syntheses and biological evaluation of indole-2 and 3-carboxamides: new selective cyclooxygenase-2 inhibitors. | Die Pharmazie 20020401 |
| Tryptophan interactions in bacteriorhodopsin: a heteronuclear solid-state NMR study. | Biochemistry 20020219 |
| Structural model of nicotinic acetylcholine receptor isotypes bound to acetylcholine and nicotine. | BMC structural biology 20020101 |
| Melatonin, serotonin, and tryptamine in some egyptian food and medicinal plants. | Journal of medicinal food 20020101 |
| The effect of copper on (3H)-tryptophan metabolism in organ cultures of rat pineal glands. | Metabolic brain disease 20011201 |
| Conserved tryptophan in cytochrome c: importance of the unique side-chain features of the indole moiety. | The Biochemical journal 20011101 |
| DNA interaction and cytotoxicity of a new series of indolo[2,3-b]quinoxaline and pyridopyrazino[2,3-b]indole derivatives. | Chemico-biological interactions 20011025 |
| Synthesis of N-alkyl substituted indolocarbazoles as potent inhibitors of human cytomegalovirus replication. | Bioorganic & medicinal chemistry letters 20010806 |
| Neural signals that regulate GnRH neurones directly during the oestrous cycle. | Reproduction (Cambridge, England) 20010701 |
| Synthesis, molecular modeling and QSAR studies in chiral 2,3-disubstituted-1,2,3,4-tetrahydro-9H-pyrido(3,4-b)indoles as potential modulators of opioid antinociception. | Bioorganic & medicinal chemistry 20010601 |
| 2-Aryl indole NK1 receptor antagonists: optimisation of the 2-aryl ring and the indole nitrogen substituent. | Bioorganic & medicinal chemistry letters 20010507 |
| Cyclization strategies for the synthesis of macrocyclic bisindolylmaleimides. | The Journal of organic chemistry 20010323 |
| Interactions of tryptamine derivatives with serotonin transporter species variants implicate transmembrane domain I in substrate recognition. | Molecular pharmacology 20010301 |
| Rebeccamycin analogues from indolo[2,3-c]carbazole. | Bioorganic & medicinal chemistry 20010201 |