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Fg-2216

CAS No.:
223387-75-5
Catalog Number:
AG00392N
Molecular Formula:
C12H9ClN2O4
Molecular Weight:
280.6639
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
99%
1 week
United States
$48
- +
5mg
99%
1 week
United States
$84
- +
10mg
99%
1 week
United States
$138
- +
25mg
99%
1 week
United States
$277
- +
50mg
99%
1 week
United States
$460
- +
100mg
99%
1 week
United States
$737
- +
Product Description
Catalog Number:
AG00392N
Chemical Name:
Fg-2216
CAS Number:
223387-75-5
Molecular Formula:
C12H9ClN2O4
Molecular Weight:
280.6639
MDL Number:
MFCD23136998
IUPAC Name:
2-[(1-chloro-4-hydroxyisoquinoline-3-carbonyl)amino]acetic acid
InChI:
InChI=1S/C12H9ClN2O4/c13-11-7-4-2-1-3-6(7)10(18)9(15-11)12(19)14-5-8(16)17/h1-4,18H,5H2,(H,14,19)(H,16,17)
InChI Key:
OUQVKRKGTAUJQA-UHFFFAOYSA-N
SMILES:
OC(=O)CNC(=O)c1nc(Cl)c2c(c1O)cccc2
UNII:
RU921DS4Z5
Properties
Complexity:
366  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
280.025g/mol
Formal Charge:
0
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
280.664g/mol
Monoisotopic Mass:
280.025g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
99.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.5  
Literature
Title Journal
Selective small molecule probes for the hypoxia inducible factor (HIF) prolyl hydroxylases. ACS chemical biology 20130719
Identification of valid housekeeping genes for quantitative RT-PCR analysis of cardiosphere-derived cells preconditioned under hypoxia or with prolyl-4-hydroxylase inhibitors. Molecular biology reports 20120401
The protective effect of prolyl-hydroxylase inhibition against renal ischaemia requires application prior to ischaemia but is superior to EPO treatment. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120301
Using NMR solvent water relaxation to investigate metalloenzyme-ligand binding interactions. Journal of medicinal chemistry 20100128
Application of a proteolysis/mass spectrometry method for investigating the effects of inhibitors on hydroxylase structure. Journal of medicinal chemistry 20090514
Gas phase reaction of substituted isoquinolines to carboxylic acids in ion trap and triple quadrupole mass spectrometers after electrospray ionization and collision-induced dissociation. Journal of the American Society for Mass Spectrometry 20080101
Properties