Tiplaxtinin
Title | Journal |
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Identification of potent Yes1 kinase inhibitors using a library screening approach. | Bioorganic & medicinal chemistry letters 20130801 |
Valproic acid induces astrocyte-dependent neurite outgrowth from cultured rat primary cortical neuron via modulation of tPA/PAI-1 activity. | Glia 20130501 |
Discovery of inhibitors of plasminogen activator inhibitor-1: structure-activity study of 5-nitro-2-phenoxybenzoic acid derivatives. | Bioorganic & medicinal chemistry letters 20111001 |
Inhibition of plasminogen activator inhibitor-1 restores skeletal muscle regeneration in untreated type 1 diabetic mice. | Diabetes 20110701 |
Theaflavin digallate inactivates plasminogen activator inhibitor: could tea help in Alzheimer's disease and obesity? | International journal of molecular medicine 20100701 |
In vitro PAI-1 inhibitory activity of oxalamide derivatives. | European journal of medicinal chemistry 20080401 |
Dose-dependent thrombus resolution due to oral plaminogen activator inhibitor (PAI)-1 inhibition with tiplaxtinin in a rat stenosis model of venous thrombosis. | Thrombosis and haemostasis 20080401 |
S35225 is a direct inhibitor of Plasminogen Activator Inhibitor type-1 activity in the blood. | Thrombosis research 20080101 |
Tiplaxtinin impairs nutritionally induced obesity in mice. | Thrombosis and haemostasis 20061201 |
Modulation of adipose tissue development by pharmacological inhibition of PAI-1. | Arteriosclerosis, thrombosis, and vascular biology 20061001 |
Synthesis and SAR of 2-carboxylic acid indoles as inhibitors of plasminogen activator inhibitor-1. | Bioorganic & medicinal chemistry letters 20050801 |
On the role of plasminogen activator inhibitor-1 in adipose tissue development and insulin resistance in mice. | Journal of thrombosis and haemostasis : JTH 20050601 |
Tiplaxtinin, a novel, orally efficacious inhibitor of plasminogen activator inhibitor-1: design, synthesis, and preclinical characterization. | Journal of medicinal chemistry 20040701 |