A therapeutic approach for wound healing by using essential oils of cupressus and juniperus species growing in Turkey.

Evidence-based complementary and alternative medicine : eCAM 20120101

The role of nutraceuticals in chemoprevention and chemotherapy and their clinical outcomes.

Journal of oncology 20120101

Anticancer efficacy of perillyl alcohol-bearing PLGA microparticles.

International journal of nanomedicine 20120101

Microbial hydroxylation of S-(-)-perillyl alcohol by Fusarium heterosporium.

Natural product communications 20111201

Nonmelanoma skin cancer chemoprevention.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20111101

Cell physiology rather than enzyme kinetics can determine the efficiency of cytochrome P450-catalyzed C-H-oxyfunctionalization.

Journal of industrial microbiology & biotechnology 20110901

Prevention of transplant coronary artery disease by prenylation inhibitors.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20110701

Evaluation of the antioxidant and antiproliferative potential of bioflavors.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110701

An efficient route to selective bio-oxidation catalysts: an iterative approach comprising modeling, diversification, and screening, based on CYP102A1.

Chembiochem : a European journal of chemical biology 20110614

Efficacy of monoterpene perillyl alcohol upon survival rate of patients with recurrent glioblastoma.

Journal of cancer research and clinical oncology 20110201

Perillyl alcohol protects against ethanol induced acute liver injury in Wistar rats by inhibiting oxidative stress, NFκ-B activation and proinflammatory cytokine production.

Toxicology 20110111

Chemo-resistant protein expression pattern of glioblastoma cells (A172) to perillyl alcohol.

Journal of proteome research 20110107

(1S,2R,4S)-1-[(Benzyl-amino)-meth-yl]-4-(prop-1-en-2-yl)cyclo-hexane-1,2-diol.

Acta crystallographica. Section E, Structure reports online 20110101

NNK-Induced Lung Tumors: A Review of Animal Model.

Journal of oncology 20110101

Hydroxyl radical and its scavengers in health and disease.

Oxidative medicine and cellular longevity 20110101

Chemical composition and antigenotoxic properties of Lippia alba essential oils.

Genetics and molecular biology 20110101

Pentoxifylline sensitizes human cervical tumor cells to cisplatin-induced apoptosis by suppressing NF-kappa B and decreased cell senescence.

BMC cancer 20110101

Chamomile (Matricaria chamomilla L.): An overview.

Pharmacognosy reviews 20110101

The anticancer drug perillyl alcohol is a Na/K-ATPase inhibitor.

Molecular and cellular biochemistry 20101201

Nonsurgical innovations in the treatment of nonmelanoma skin cancer.

The Journal of clinical and aesthetic dermatology 20100601

Dynamic proteomic overview of glioblastoma cells (A172) exposed to perillyl alcohol.

Journal of proteomics 20100310

A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer.

Cancer prevention research (Philadelphia, Pa.) 20100201

The promise of natural products for blocking early events in skin carcinogenesis.

Cancer prevention research (Philadelphia, Pa.) 20100201

Perillyl alcohol and methyl jasmonate sensitize cancer cells to cisplatin.

Anti-cancer drugs 20100101

Tumour-specific HMG-CoAR is an independent predictor of recurrence free survival in epithelial ovarian cancer.

BMC cancer 20100101

Sensitization of cervix cancer cells to Adriamycin by Pentoxifylline induces an increase in apoptosis and decrease senescence.

Molecular cancer 20100101

Expressed sequence tags from cephalic chemosensory organs of the northern walnut husk fly, Rhagoletis suavis, including a putative canonical odorant receptor.

Journal of insect science (Online) 20100101

Antineoplastic activities of MT81 and its structural analogue in Ehrlich ascites carcinoma-bearing Swiss Albino mice.

Oxidative medicine and cellular longevity 20100101

Mechanism of statin-induced contractile dysfunction in rat cultured skeletal myofibers.

Journal of pharmacological sciences 20100101

Correlation of tumor topography and peritumoral edema of recurrent malignant gliomas with therapeutic response to intranasal administration of perillyl alcohol.

Investigational new drugs 20091201

Pharmacotherapy of actinic keratosis.

Expert opinion on pharmacotherapy 20091201

Statin-induced muscle damage and atrogin-1 induction is the result of a geranylgeranylation defect.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090901

Tricistronic overexpression of cytochrome P450cam, putidaredoxin, and putidaredoxin reductase provides a useful cell-based catalytic system.

Biotechnology letters 20090901

Perillyl alcohol attenuates Ras-ERK signaling to inhibit murine skin inflammation and tumorigenesis.

Chemico-biological interactions 20090515

Components of lemon essential oil attenuate dementia induced by scopolamine.

Nutritional neuroscience 20090401

[Natural compounds in chemoprevention of esophageal squamous cell tumors--experimental studies].

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20090201

GO Explorer: A gene-ontology tool to aid in the interpretation of shotgun proteomics data.

Proteome science 20090101

Protective effects of mastic oil from Pistacia lentiscus variation chia against experimental growth of lewis lung carcinoma.

Nutrition and cancer 20090101

A transcriptomic computational analysis of mastic oil-treated Lewis lung carcinomas reveals molecular mechanisms targeting tumor cell growth and survival.

BMC medical genomics 20090101

Targeted therapy in the treatment of malignant gliomas.

OncoTargets and therapy 20090101

High-performance liquid chromatographic and pharmacokinetic analyses of an intravenous submicron emulsion of perillyl alcohol in rats.

Journal of pharmaceutical and biomedical analysis 20081201

Sensitive determination of monoterpene alcohols in urine by HPLC-FLD combined with ESI-MS detection after online-solid phase extraction of the monoterpene-coumarincarbamate derivates.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081115

Fragrance material review on p-mentha-1,8-dien-7-ol.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081101

Mechanism of in vitro pancreatic cancer cell growth inhibition by melanoma differentiation-associated gene-7/interleukin-24 and perillyl alcohol.

Cancer research 20080915

Preliminary results from a phase I/II study of perillyl alcohol intranasal administration in adults with recurrent malignant gliomas.

Surgical neurology 20080901

Gateways to clinical trials.

Methods and findings in experimental and clinical pharmacology 20080901

Ras pathway activation in gliomas: a strategic target for intranasal administration of perillyl alcohol.

Archivum immunologiae et therapiae experimentalis 20080801

Synthesis of phosphatidylated-monoterpene alcohols catalyzed by phospholipase D and their antiproliferative effects on human cancer cells.

Bioorganic & medicinal chemistry letters 20080715

Chemoprevention by perillyl alcohol coupled with viral gene therapy reduces pancreatic cancer pathogenesis.

Molecular cancer therapeutics 20080701

A pilot study of perillyl alcohol in pancreatic cancer.

The Journal of surgical research 20080615

Phase II trial of daily oral perillyl alcohol (NSC 641066) in treatment-refractory metastatic breast cancer.

Cancer chemotherapy and pharmacology 20080601

Anti-inflammatory senescence actives 5203-L molecule to promote healthy aging and prolongation of lifespan.

Rejuvenation research 20080401

Phase 1 study of topical perillyl alcohol cream for chemoprevention of skin cancer.

Nutrition and cancer 20080101

Prevalence of bortezomib-resistant constitutive NF-kappaB activity in mantle cell lymphoma.

Molecular cancer 20080101

Biphenylalkylacetylhydroquinone ethers suppress the proliferation of murine B16 melanoma cells.

Anticancer research 20080101

Discovery of new biocatalysts for the glycosylation of terpenoid scaffolds.

Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

PatternLab for proteomics: a tool for differential shotgun proteomics.

BMC bioinformatics 20080101

Anti-thrombin as a prognostic biomarker candidate for patients with recurrent glioblastoma multiform under treatment with perillyl alcohol.

Journal of experimental therapeutics & oncology 20080101

Rab-small GTPases are involved in fluvastatin and pravastatin-induced vacuolation in rat skeletal myofibers.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20071201

Perillyl Alcohol Protects Against Fe-NTA-Induced Nephrotoxicity and Early Tumor Promotional Events in Rat Experimental Model.

Evidence-based complementary and alternative medicine : eCAM 20071201

Perillyl alcohol and perillic acid induced cell cycle arrest and apoptosis in non small cell lung cancer cells.

Cancer letters 20071118

Perillyl alcohol and genistein differentially regulate PKB/Akt and 4E-BP1 phosphorylation as well as eIF4E/eIF4G interactions in human tumor cells.

Archives of biochemistry and biophysics 20070901

Cloning of four genes involved in limonene hydroxylation from Enterobacter cowanii 6L.

Journal of microbiology and biotechnology 20070701

Cell cycle arrest by the isoprenoids perillyl alcohol, geraniol, and farnesol is mediated by p21(Cip1) and p27(Kip1) in human pancreatic adenocarcinoma cells.

The Journal of pharmacology and experimental therapeutics 20070301

Anaplastic oligodendroglioma responding favorably to intranasal delivery of perillyl alcohol: a case report and literature review.

Surgical neurology 20061201

Evaluation of characteristic aroma compounds of Citrus natsudaidai Hayata (Natsudaidai) cold-pressed peel oil.

Bioscience, biotechnology, and biochemistry 20060801

Polycyclic aromatic hydrocarbon-induced CYP1B1 activity is suppressed by perillyl alcohol in MCF-7 cells.

Toxicology and applied pharmacology 20060601

Perillyl alcohol inhibits the expression and function of the androgen receptor in human prostate cancer cells.

Cancer letters 20060518

Recent advances in the molecular genetics of malignant gliomas disclose targets for antitumor agent perillyl alcohol.

Surgical neurology 20060101

Perillyl alcohol induces c-Myc-dependent apoptosis in Bcr/Abl-transformed leukemia cells.

Oncology 20060101

Apocynin derivatives interrupt intracellular signaling resulting in decreased migration in breast cancer cells.

Journal of biomedicine & biotechnology 20060101

Mastic oil from Pistacia lentiscus var. chia inhibits growth and survival of human K562 leukemia cells and attenuates angiogenesis.

Nutrition and cancer 20060101

In vitro induction of apoptosis in U937 cells by perillyl alcohol with sensitization by pentoxifylline: increased BCL-2 and BAX protein expression.

Chemotherapy 20060101

Effects of perillyl alcohol and heat shock treatment in gene expression of human lung adenocarcinoma cell line A549.

Journal of experimental therapeutics & oncology 20060101

Perillyl alcohol inhibits a calcium-dependent constitutive nuclear factor-kappaB pathway.

Cancer research 20050915

Gateways to clinical trials.

Methods and findings in experimental and clinical pharmacology 20050601

Effect of D-limonene on immune response in BALB/c mice with lymphoma.

International immunopharmacology 20050501

Perillyl alcohol induces apoptosis in human glioblastoma multiforme cells.

Oncology reports 20050501

CaaX-prenyltransferases are essential for expression of genes involvedin the early stages of monoterpenoid biosynthetic pathway in Catharanthus roseus cells.

Plant molecular biology 20050401

An HPLC method for quantitation of perillyl alcohol in a topical pharmaceutical cream formulation.

Journal of pharmaceutical and biomedical analysis 20050309

Fumigant toxicity of the essential oils of some African plants against Anopheles gambiae sensu stricto.

Phytomedicine : international journal of phytotherapy and phytopharmacology 20050301

Sle1ab mediates the aberrant activation of STAT3 and Ras-ERK signaling pathways in B lymphocytes.

Journal of immunology (Baltimore, Md. : 1950) 20050201

The number of functional olfactory receptor genes and the relative size of olfactory brain structures are poor predictors of olfactory discrimination performance with enantiomers.

Chemical senses 20050201

A novel psychrotrophic fungus, Mortierella minutissima, for D-limonene biotransformation.

Biotechnology letters 20050201

Cancer preventive role of selected dietary factors.

Indian journal of cancer 20050101

Protein and m-RNA expression of farnesyl-transferases, RhoA and RhoB in rat liver hepatocytes: action of perillyl alcohol and vitamin A in vivo.

Journal of biomedical science 20050101

Regio- and stereoselective fungal oxyfunctionalisation of limonenes.

Zeitschrift fur Naturforschung. C, Journal of biosciences 20050101

Terpenoids as plant antioxidants.

Vitamins and hormones 20050101

Inherent growth advantage of (pre)malignant hepatocytes associated with nuclear translocation of pro-transforming growth factor alpha.

British journal of cancer 20041129

A pilot surrogate end point biomarker trial of perillyl alcohol in breast neoplasia.

Clinical cancer research : an official journal of the American Association for Cancer Research 20041115

Perillyl alcohol is an angiogenesis inhibitor.

The Journal of pharmacology and experimental therapeutics 20041101

A phase I trial of perillyl alcohol administered four times daily for 14 days out of 28 days.

Cancer chemotherapy and pharmacology 20041001

Repellency of essential oils of some Kenyan plants against Anopheles gambiae.

Phytochemistry 20041001

Studies of the isoprenoid-mediated inhibition of mevalonate synthesis applied to cancer chemotherapy and chemoprevention.

Experimental biology and medicine (Maywood, N.J.) 20040701

Antinociceptive effects of the essential oil of Dracocephalum kotschyi in the mouse writhing test.

Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20040420

Perillyl alcohol inhibits human breast cancer cell growth in vitro and in vivo.

Breast cancer research and treatment 20040401

Using patients as their own controls for cost evaluation of phase I clinical trials.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040401

Perillyl alcohol-mediated inhibition of lung cancer cell line proliferation: potential mechanisms for its chemotherapeutic effects.

Toxicology and applied pharmacology 20040301

Gateways to clinical trials.

Methods and findings in experimental and clinical pharmacology 20040301

Olfactory discrimination ability of human subjects for enantiomers with an isopropenyl group at the chiral center.

Chemical senses 20040201

Development of a perillyl alcohol topical cream formulation.

International journal of pharmaceutics 20040128

Transformation of terpenes using a Picea abies suspension culture.

Journal of biotechnology 20040122

Effects of POH in combination with STI571 on the proliferation and apoptosis of K562 cells.

Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20040101

BAK overexpression mediates p53-independent apoptosis inducing effects on human gastric cancer cells.

BMC cancer 20040101

Monoterpenes enhanced the sensitivity of head and neck cancer cells to radiation treatment in vitro.

Anticancer research 20040101

Effect of antiproliferative agents on vascular function in normal and in vitro balloon-injured porcine coronary arteries.

European journal of pharmacology 20031114

Phase I trial of perillyl alcohol administered four times daily continuously.

Cancer chemotherapy and pharmacology 20031101

Cytotoxicity of perillyl alcohol against cancer cells is potentiated by hyperthermia.

International journal of radiation oncology, biology, physics 20031101

Perillyl alcohol and perillaldehyde induced cell cycle arrest and cell death in BroTo and A549 cells cultured in vitro.

Life sciences 20031017

Studies with cytotoxic agents suggest that apoptosis is not a major determinant of clonogenic death in neuroblastoma cells.

European journal of cancer (Oxford, England : 1990) 20031001

Anti-leukemia effect of perillyl alcohol in Bcr/Abl-transformed cells indirectly inhibits signaling through Mek in a Ras- and Raf-independent fashion.

Clinical cancer research : an official journal of the American Association for Cancer Research 20031001

Perillyl alcohol as a radio-/chemosensitizer in malignant glioma.

The Journal of biological chemistry 20030919

Perillyl alcohol mediated radiosensitization via augmentation of the Fas pathway in prostate cancer cells.

The Prostate 20030915

Gateways to clinical trials.

Methods and findings in experimental and clinical pharmacology 20030901

Phase II trial of perillyl alcohol (NSC 641066) administered daily in patients with metastatic androgen independent prostate cancer.

Investigational new drugs 20030801

In situ detection of neoplastic transformation and chemopreventive effects in rat esophagus epithelium using angle-resolved low-coherence interferometry.

Cancer research 20030701

Monoterpene regulation of Ras and Ras-related protein expression.

Journal of lipid research 20030601

A phase I trial of perillyl alcohol in patients with advanced solid tumors.

Cancer chemotherapy and pharmacology 20030601

Perillyl alcohol as a chemopreventive agent in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis.

Cancer research 20030515

Mechanism-based in vitro screening of potential cancer chemopreventive agents.

Mutation research 20030101

Skin cancer chemoprevention: strategies to save our skin.

Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20030101

Effects of perillyl alcohol in glial C6 cell line in vitro and anti-metastatic activity in chorioallantoic membrane model.

International journal of molecular medicine 20021201

Sensitive biomonitoring of monoterpene exposure by gas chromatographic-mass spectrometric measurement of hydroxy terpenes in urine.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20021125

Monoterpenes inhibit proliferation of human colon cancer cells by modulating cell cycle-related protein expression.

Cancer letters 20020726

Effects of perillyl alcohol on melanoma in the TPras mouse model.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20020601

A phase II trial of daily perillyl alcohol in patients with advanced ovarian cancer: Eastern Cooperative Oncology Group Study E2E96.

Gynecologic oncology 20020601

Metabolism of (+)- and (-)-limonenes to respective carveols and perillyl alcohols by CYP2C9 and CYP2C19 in human liver microsomes.

Drug metabolism and disposition: the biological fate of chemicals 20020501

Antileukemia activity of perillyl alcohol (POH): uncoupling apoptosis from G0/G1 arrest suggests that the primary effect of POH on Bcr/Abl-transformed cells is to induce growth arrest.

Leukemia 20020201

Induction of cytostasis in mammary carcinoma cells treated with the anticancer agent perillyl alcohol.

Carcinogenesis 20020101

Sex differences in the metabolism of (+)- and (-)-limonene enantiomers to carveol and perillyl alcohol derivatives by cytochrome p450 enzymes in rat liver microsomes.

Chemical research in toxicology 20020101

Weight-loss drugs and supplements: are there safer alternatives?

Medical hypotheses 20020101

Phase I study of perillyl alcohol in patients with refractory malignancies.

Cancer biology & therapy 20020101

Effects of the isoprenoids perillyl alcohol and farnesol on apoptosis biomarkers in pancreatic cancer chemoprevention.

Anticancer research 20020101

Micronutrients in cancer chemoprevention.

Cancer metastasis reviews 20020101

Phase II trial of perillyl alcohol in patients with metastatic colorectal cancer.

International journal of gastrointestinal cancer 20020101

Species differences in the metabolism of (+)- and (-)-limonenes and their metabolites, carveols and carvones, by cytochrome P450 enzymes in liver microsomes of mice, rats, guinea pigs, rabbits, dogs, monkeys, and humans.

Drug metabolism and pharmacokinetics 20020101

Biotransformation of limonene by Pseudomonas putida.

Applied microbiology and biotechnology 20010501

Breast cancer chemoprevention: beyond tamoxifen.

Breast cancer research : BCR 20010101

Correlation of chemopreventive efficacy data from the human epidermal cell assay with in vivo data.

Anticancer research 20000101

Perillyl alcohol dehydrogenase from a soil pseudomonad.

Biochemical and biophysical research communications 19660525