Hyodeoxycholic acid
Title | Journal |
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11β-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice. | Molecular metabolism 20140801 |
Human UDP-glucuronosyltransferases: feedback loops between substrates and ligands of their transcription factors. | Biochemical pharmacology 20121015 |
BASIC--a bile acid-sensitive ion channel highly expressed in bile ducts. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20121001 |
Gender, but not CYP7A1 or SLCO1B1 polymorphism, affects the fasting plasma concentrations of bile acids in human beings. | Basic & clinical pharmacology & toxicology 20120301 |
A tandem mass spectrometric study of bile acids: interpretation of fragmentation pathways and differentiation of steroid isomers. | Steroids 20120201 |
Gender-divergent profile of bile acid homeostasis during aging of mice. | PloS one 20120101 |
Dysfunction of organic anion transporting polypeptide 1a1 alters intestinal bacteria and bile acid metabolism in mice. | PloS one 20120101 |
Effects of human and porcine bile on the proteome of Helicobacter hepaticus. | Proteome science 20120101 |
Refined Qingkailing Protects MCAO Mice from Endoplasmic Reticulum Stress-Induced Apoptosis with a Broad Time Window. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
Chinese medicine injection qingkailing for treatment of acute ischemia stroke: a systematic review of randomized controlled trials. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
A novel 'target constituent knock-out' strategy coupled with TLC, UPLC-ELSD and microcalorimetry for preliminary screening of antibacterial constituents in Calculus bovis. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111115 |
Inhibition of human UGT2B7 gene expression in transgenic mice by the constitutive androstane receptor. | Molecular pharmacology 20110601 |
Regulated phosphorylation of a major UDP-glucuronosyltransferase isozyme by tyrosine kinases dictates endogenous substrate selection for detoxification. | The Journal of biological chemistry 20110114 |
Differentiation of various traditional Chinese medicines derived from animal bile and gallstone: simultaneous determination of bile acids by liquid chromatography coupled with triple quadrupole mass spectrometry. | Journal of chromatography. A 20110107 |
Diurnal variations of mouse plasma and hepatic bile acid concentrations as well as expression of biosynthetic enzymes and transporters. | PloS one 20110101 |
Profiling circulating and urinary bile acids in patients with biliary obstruction before and after biliary stenting. | PloS one 20110101 |
Voluntary wheel running exercise and dietary lactose concomitantly reduce proportion of secondary bile acids in rat feces. | Journal of applied physiology (Bethesda, Md. : 1985) 20100901 |
Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes. | Aging 20100701 |
Regulation of bile acid synthesis by fat-soluble vitamins A and D. | The Journal of biological chemistry 20100507 |
Identification of human UGT2B7 as the major isoform involved in the O-glucuronidation of chloramphenicol. | Drug metabolism and disposition: the biological fate of chemicals 20100301 |
Liver X receptor agonist methyl-3β-hydroxy-5α,6α-epoxycholanate attenuates atherosclerosis in apolipoprotein E knockout mice without increasing plasma triglyceride. | Pharmacology 20100101 |
Challenges predicting ligand-receptor interactions of promiscuous proteins: the nuclear receptor PXR. | PLoS computational biology 20091201 |
Consumption of some polyphenols reduces fecal deoxycholic acid and lithocholic acid, the secondary bile acids of risk factors of colon cancer. | Journal of agricultural and food chemistry 20090923 |
3-ketocholanoic acid is the major in vitro human hepatic microsomal metabolite of lithocholic acid. | Drug metabolism and disposition: the biological fate of chemicals 20090901 |
Serum bile acid profiling reflects enterohepatic detoxification state and intestinal barrier function in inflammatory bowel disease. | World journal of gastroenterology 20090707 |
Improved analysis of bile acids in tissues and intestinal contents of rats using LC/ESI-MS. | Journal of lipid research 20090101 |
Bear bile: dilemma of traditional medicinal use and animal protection. | Journal of ethnobiology and ethnomedicine 20090101 |
The inhibitory effects of cholalic acid and hyodeoxycholalic acid on the expression of TNFalpha and IL-1beta after cerebral ischemia in rats. | Archives of pharmacal research 20090101 |
Regulation of sulfotransferase and UDP-glucuronosyltransferase gene expression by the PPARs. | PPAR research 20090101 |
Novel polymorphic human UDP-glucuronosyltransferase 2A3: cloning, functional characterization of enzyme variants, comparative tissue expression, and gene induction. | Molecular pharmacology 20080901 |
Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies. | Journal of medicinal chemistry 20080327 |
Biotransformation of lithocholic acid by rat hepatic microsomes: metabolite analysis by liquid chromatography/mass spectrometry. | Drug metabolism and disposition: the biological fate of chemicals 20080201 |
Use of selected chemical markers in combination with a multiple regression model to assess the contribution of domesticated animal sources of fecal pollution in the environment. | Chemosphere 20071101 |
[Determination of chyodeoxycholic acid in Bile Arisaema by HPLC-ELSD]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070801 |
Comparative study on major bioactive components in natural, artificial and in-vitro cultured Calculus Bovis. | Chemical & pharmaceutical bulletin 20070101 |
Simultaneous determination of geniposide, baicalin, cholic acid and hyodeoxycholic acid in rat serum for the pharmacokinetic investigations by high performance liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060914 |
3alpha-6alpha-Dihydroxy-7alpha-fluoro-5beta-cholanoate (UPF-680), physicochemical and physiological properties of a new fluorinated bile acid that prevents 17alpha-ethynyl-estradiol-induced cholestasis in rats. | Toxicology and applied pharmacology 20060715 |
Role for enhanced faecal excretion of bile acid in hydroxysteroid sulfotransferase-mediated protection against lithocholic acid-induced liver toxicity. | Xenobiotica; the fate of foreign compounds in biological systems 20060701 |
Determination of three bile acids in artificial Calculus Bovis and its medicinal preparations by micellar electrokinetic capillary electrophoresis. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060606 |
Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides. | Journal of hepatology 20060401 |
Simultaneous determination of nine components in Qingkailing injection by HPLC/ELSD/DAD and its application to the quality control. | Journal of pharmaceutical and biomedical analysis 20060303 |
Enzymatic production of bile Acid glucuronides used as analytical standards for liquid chromatography-mass spectrometry analyses. | Molecular pharmaceutics 20060101 |
Resistance to ursodeoxycholic acid-induced growth arrest can also result in resistance to deoxycholic acid-induced apoptosis and increased tumorgenicity. | BMC cancer 20060101 |
Isolation and determination of bile acids. | European journal of drug metabolism and pharmacokinetics 20060101 |
Simultaneous determination of major bioactive components in Qingkailing injection by high-performance liquid chromatography with evaporative light scattering detection. | Chemical & pharmaceutical bulletin 20051101 |
[Simultaneous determination of five groups of components in qingkailing injection by high performance liquid chromatography with photo diode array detector and evaporative light scattering detector]. | Se pu = Chinese journal of chromatography 20050901 |
Interfacial properties of most monofluorinated bile acids deviate markedly from the natural congeners: studies with the Langmuir-Pockels surface balance. | Journal of lipid research 20050301 |
Effect of dried plums on colon cancer risk factors in rats. | Nutrition and cancer 20050101 |
Identification of UGT2B9*2 and UGT2B33 isolated from female rhesus monkey liver. | Archives of biochemistry and biophysics 20040601 |
Effects of ileo-rectal anastomosis on cholesterol metabolism in pigs fed either casein or extruded soya beans. | The British journal of nutrition 20040501 |
[Study on extraction technique of HDCA]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040501 |
UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients. | Breast cancer research : BCR 20040101 |
Fluorescence resonance energy transfer in a novel cyclodextrin-peptide conjugate for detecting steroid molecules. | Bioorganic & medicinal chemistry letters 20031215 |
Substrate specificities of rat oatp1 and ntcp: implications for hepatic organic anion uptake. | American journal of physiology. Gastrointestinal and liver physiology 20031101 |
Steroids in the intestinal tract of rats are affected by dietary-fibre-rich barley-based diets. | The British journal of nutrition 20031101 |
Peroxisome proliferator-activated receptor alpha induces hepatic expression of the human bile acid glucuronidating UDP-glucuronosyltransferase 2B4 enzyme. | The Journal of biological chemistry 20030829 |
Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7. | Biochemical pharmacology 20030201 |
The cytotoxicity of hydrophobic bile acids is ameliorated by more hydrophilic bile acids in intestinal cell lines IEC-6 and Caco-2. | Oncology reports 20030101 |
Dietary bile acids inhibit potentially elemental diet-induced small intestinal atrophy in rats. | International journal of molecular medicine 20021101 |
[Study on effect of qingkailing injection and its active principle in inducing cell apoptosis in human acute promyelocytic leukemia]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20011101 |
Hyodeoxycholic acid efficiently suppresses atherosclerosis formation and plasma cholesterol levels in mice. | Journal of lipid research 20010801 |
Effect of bile salts on colonic mucus secretion in isolated vascularly perfused rat colon. | Digestive diseases and sciences 20010601 |
Hydrophilic and hydrophobic bile acids exhibit different cytotoxicities through cytolysis, interleukin-8 synthesis and apoptosis in the intestinal epithelial cell lines. IEC-6 and Caco-2 cells. | Scandinavian journal of gastroenterology 20010501 |
UGT2B23, a novel uridine diphosphate-glucuronosyltransferase enzyme expressed in steroid target tissues that conjugates androgen and estrogen metabolites. | Endocrinology 19991201 |
Reinduction of the hypnotic effects of thiopental with NSAIDs by decreasing thiopental plasma protein binding in humans. | Acta anaesthesiologica Scandinavica 19930401 |
Complementary deoxyribonucleic acid cloning and expression of a human liver uridine diphosphate-glucuronosyltransferase glucuronidating carboxylic acid-containing drugs. | The Journal of pharmacology and experimental therapeutics 19930101 |
Isolation and characterization of hyodeoxycholic-acid: UDP-glucuronosyltransferase from human liver. | European journal of biochemistry 19910901 |