Ethyl cyanoacetate
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Schiff base structured acid-base cooperative dual sites in an ionic solid catalyst lead to efficient heterogeneous knoevenagel condensations. | Chemistry (Weinheim an der Bergstrasse, Germany) 20121001 |
Design, synthesis, antimicrobial, anti-inflammatory and analgesic activity of novel isoxazolyl pyrimido[4,5-b]quinolines and isoxazolyl chromeno[2,3-d]pyrimidin-4-ones. | European journal of medicinal chemistry 20120901 |
Synthesis of some novel biologically active disperse dyes derived from 4-methyl-2,6-dioxo-1-propyl-1,2,5,6-tetrahydro-pyridine-3-carbonitrile as coupling component and their colour assessment on polyester fabrics. | Molecules (Basel, Switzerland) 20120725 |
Ultrasound-promoted one-pot, three-component synthesis of spiro[indoline-3,1'-pyrazolo[1,2-b]phthalazine] derivatives. | Molecules (Basel, Switzerland) 20120723 |
Condensation reactions of 3-oxo-2-arylhydrazonopropanals with active methylene reagents: formation of 2-hydroxy- and 2-amino-6-substituted-5-arylazonicotinates and pyrido[3,2-c]cinnolines via 6π-electrocyclization reactions. | Molecules (Basel, Switzerland) 20120530 |
Four-component synthesis of 1,2-dihydropyridine derivatives and their evaluation as anticancer agents. | Medicinal chemistry (Shariqah (United Arab Emirates)) 20120501 |
(E)-Ethyl 2-cyano-3-(furan-2-yl)acrylate. | Acta crystallographica. Section E, Structure reports online 20120501 |
Synthesis, anticancer activity and radiosensitizing evaluation of some new 2-pyridone derivatives. | Arzneimittel-Forschung 20120301 |
6-(2-Methyl-prop-yl)-4-oxo-2-sulfanyl-idene-1,2,3,4-tetra-hydro-pyrimidine-5-carbonitrile. | Acta crystallographica. Section E, Structure reports online 20120301 |
Ethyl 5-amino-3-(pyridin-4-yl)-1-(2,4,6-tri-chloro-phen-yl)-1H-pyrazole-4-carb-oxyl-ate dimethyl sulfoxide hemisolvate. | Acta crystallographica. Section E, Structure reports online 20120301 |
Rapid and efficient ultrasound-assisted method for the combinatorial synthesis of spiro[indoline-3,4'-pyrano[2,3-c]pyrazole] derivatives. | ACS combinatorial science 20120109 |
Highly regio- and stereoselective Diels-Alder cycloadditions via two-step and multicomponent reactions promoted by infrared irradiation under solvent-free conditions. | International journal of molecular sciences 20120101 |
Synthesis of substituted isoquinolines via Pd-catalyzed cross-coupling approaches. | Organic letters 20111202 |
Synthesis and in vitro EGFR (ErbB1) tyrosine kinase inhibitory activity of 4-N-substituted 6-aryl-7H-pyrrolo[2,3-d]pyrimidine-4-amines. | European journal of medicinal chemistry 20111201 |
(E)-Ethyl 2-cyano-3-(2,4-dimeth-oxy-phen-yl)prop-2-enoate. | Acta crystallographica. Section E, Structure reports online 20111101 |
2-Amino-4-phenyl-5,6-dihydro-benzo[h]quinoline-3-carbonitrile-3-amino-1-phenyl-9,10-dihydro-phenanthrene-2,4-dicarbonitrile (5/3). | Acta crystallographica. Section E, Structure reports online 20111101 |
2-Amino-4-(3,4-dimeth-oxy-phen-yl)-5,6-dihydro-benzo[h]quinoline-3-carbo-nitrile-3-amino-1-(3,4-dimeth-oxy-phen-yl)-9,10-dihydro-phenanthrene-2,4-dicarbonitrile (1/19). | Acta crystallographica. Section E, Structure reports online 20111101 |
2-Amino-4-(4-chloro-phen-yl)-5,6-dihydro-benzo[h]quinoline-3-carbonitrile-3-amino-1-(4-chloro-phen-yl)-9,10-dihydro-phenanthrene-2,4-dicarbonitrile (1/4). | Acta crystallographica. Section E, Structure reports online 20111101 |
3-Amino-1-(4-bromo-phen-yl)-9,10-dihydro-phenanthrene-2,4-dicarbonitrile. | Acta crystallographica. Section E, Structure reports online 20111001 |
4-(4-Chloro-phen-yl)-8-methyl-2-oxo-1,2,3,4,4a,5,6,7-octa-hydro-quinoline-3-carbonitrile. | Acta crystallographica. Section E, Structure reports online 20111001 |
4-(4-Chloro-phen-yl)-8-methyl-2-oxo-1,2,5,6,7,8-hexa-hydro-quinoline-3-carbonitrile. | Acta crystallographica. Section E, Structure reports online 20111001 |
Ethyl (2E)-2-cyano-3-(1-methyl-1H-pyrrol-2-yl)prop-2-enoate. | Acta crystallographica. Section E, Structure reports online 20110901 |
Ethyl 6-amino-8-(4-chloro-phen-yl)-9-nitro-2,3,4,8-tetra-hydro-pyrido[2,1-b][1,3]thia-zine-7-carboxyl-ate. | Acta crystallographica. Section E, Structure reports online 20110901 |
3-Amino-1-(2H-1,3-benzodioxol-5-yl)-9,10-dihydro-phenanthrene-2,4-dicarbonitrile. | Acta crystallographica. Section E, Structure reports online 20110901 |
3-Amino-1-(4-meth-oxy-phen-yl)-9,10-dihydro-phenanthrene-2,4-dicarbonitrile. | Acta crystallographica. Section E, Structure reports online 20110901 |
4-(4-Meth-oxy-phen-yl)-2-oxo-1,2,5,6-tetra-hydro-benzo[h]quinoline-3-carbo-nitrile. | Acta crystallographica. Section E, Structure reports online 20110901 |
4-(1,3-Benzodioxol-5-yl)-2-oxo-1,2,5,6-tetra-hydro-benzo[h]quinoline-3-carbo-nitrile. | Acta crystallographica. Section E, Structure reports online 20110901 |
4-(4-Bromo-phen-yl)-2-oxo-1,2,5,6-tetra-hydro-benzo[h]quinoline-3-carbonitrile. | Acta crystallographica. Section E, Structure reports online 20110901 |
2-Oxo-4-(thio-phen-2-yl)-1,2,5,6-tetra-hydro-benzo[h]quinoline-3-carbonitrile. | Acta crystallographica. Section E, Structure reports online 20110901 |
2-Oxo-4-phenyl-1,2,5,6-tetra-hydro-benzo[h]quinoline-3-carbonitrile. | Acta crystallographica. Section E, Structure reports online 20110901 |
Ethyl 2-amino-4-phenyl-4H-1-benzo-thieno[3,2-b]pyran-3-carboxyl-ate. | Acta crystallographica. Section E, Structure reports online 20110801 |
(E)-Ethyl 2-cyano-3-(1H-pyrrol-2-yl)acrylate. | Acta crystallographica. Section E, Structure reports online 20110801 |
(Z)-Ethyl 2-cyano-2-{2-[5,6-dimethyl-4-(thio-phen-2-yl)-1H-pyrazolo-[3,4-b]pyridin-3-yl]hydrazinylidene}acetate. | Acta crystallographica. Section E, Structure reports online 20110801 |
Synthesis of functionalized 2-aminohydropyridines and 2-pyridinones via domino reactions of arylamines, methyl propiolate, aromatic aldehydes, and substituted acetonitriles. | ACS combinatorial science 20110711 |
Synthesis, antitumor and antimicrobial activities of 4-(4-chlorophenyl)-3-cyano-2-(β-O-glycosyloxy)-6-(thien-2-yl)-nicotinonitrile. | European journal of medicinal chemistry 20110701 |
Synthesis of some novel pyrazolo[1,5-a]pyrimidine derivatives and their application as disperse dyes. | Molecules (Basel, Switzerland) 20110622 |
Synthesis and antimicrobial evaluation of some 6-aryl-5-cyano-2-thiouracil derivatives. | Acta pharmaceutica (Zagreb, Croatia) 20110601 |
Synthesis of pyridin-2(1H)-one derivatives via enamine cyclization. | The Journal of organic chemistry 20110520 |
Synthesis and biological evaluation of 4-styrylcoumarin derivatives as inhibitors of TNF-α and IL-6 with anti-tubercular activity. | Bioorganic & medicinal chemistry letters 20110415 |
(E)-Ethyl 2-cyano-3-[4-(4,5-diphenyl-1H-imidazol-2-yl)phen-yl]acrylate dihydrate. | Acta crystallographica. Section E, Structure reports online 20110301 |
Convenient synthesis of polyfunctional dihydrothiophenes with tandem reaction of 1,3-thiazolidinedione, aldehyde, arylamine and ethyl cyanoacetate. | Molecular diversity 20110201 |
Synthesis and biological activity of pyrazolothienotetrahydroisoquinoline and [1,2,4]triazolo[3,4-a]thienotetrahydroisoquinoline derivatives. | European journal of medicinal chemistry 20110201 |
Ethyl 2-amino-6-benzyl-4,5,6,7-tetra-hydro-thieno[2,3-c]pyridine-3-carboxyl-ate. | Acta crystallographica. Section E, Structure reports online 20110101 |
Synthesis of new pyrimidine derivatives with evaluation of their anti-inflammatory and analgesic activities. | Acta poloniae pharmaceutica 20110101 |
Novel benzimidazole derivatives as expected anticancer agents. | Acta poloniae pharmaceutica 20110101 |
Design, Synthesis and Biological Evaluation of Novel Pyrimido[4,5-d]pyrimidine CDK2 Inhibitors as Anti-Tumor Agents. | Scientia pharmaceutica 20110101 |
Novel synthesis and antitumor evaluation of polyfunctionally substituted heterocyclic compounds derived from 2-cyano-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-acetamide. | Molecules (Basel, Switzerland) 20101227 |
(E)-Ethyl 2-cyano-3-[5-nitro-2-(pyrrolidin-1-yl)phen-yl]acrylate. | Acta crystallographica. Section E, Structure reports online 20101001 |
Green one pot solvent-free synthesis of pyrano[2,3-c]-pyrazoles and pyrazolo[1,5-a]pyrimidines. | Molecules (Basel, Switzerland) 20100920 |
L-Histidine and L-arginine promote Knoevenagel reaction in water. | Amino acids 20100801 |
Mono(NCN-pincer palladium)-metalloporphyrin catalysts: evidence for supramolecular bimetallic catalysis. | Dalton transactions (Cambridge, England : 2003) 20100721 |
One-pot synthesis of 4,6-diaryl-2-oxo(imino)-1,2-dihydropyridine-3-carbonitrile; a New Scaffold for p38alpha MAP kinase inhibition. | Journal of combinatorial chemistry 20100712 |
A convenient one-pot synthesis of 3-amino-2, 5-dihydropyridazine and pyrimidine derivatives in the presence of high surface area MgO as a highly effective heterogeneous base catalyst. | Molecular diversity 20100501 |
Microwave-assisted and efficient solvent-free knoevenagel condensation. A sustainable protocol using porous calcium hydroxyapatite as catalyst. | Molecules (Basel, Switzerland) 20100204 |
Ethyl 2-amino-7,7-dimethyl-2',5-dioxo-spiro-[5,6,7,8-tetra-hydro-4H-chromene-4,3'(2'H)-1H-indole]-3-carboxyl-ate. | Acta crystallographica. Section E, Structure reports online 20100201 |
Ultrasound-assisted one-pot, three-component synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones. | Ultrasonics sonochemistry 20100101 |
Discovery of colon tumor cell growth inhibitory agents through a combinatorial approach. | European journal of medicinal chemistry 20100101 |
Novel 6,8-dibromo-4(3H)-quinazolinone derivatives of promising anti-inflammatory and analgesic properties. | Acta poloniae pharmaceutica 20100101 |
A new and facile synthetic approach to substituted 2-thioxoquinazolin-4-ones by the annulation of a pyrimidine derivative. | Beilstein journal of organic chemistry 20100101 |
New pyridone, thioxopyridine, pyrazolopyridine and pyridine derivatives that modulate inflammatory mediators in stimulated RAW 264.7 murine macrophage. | European journal of medicinal chemistry 20091101 |
(E)-Ethyl 3-(3-bromo-phen-yl)-2-cyano-acrylate. | Acta crystallographica. Section E, Structure reports online 20091101 |
(E)-Ethyl 2-cyano-3-(3,4-dihydr-oxy-5-nitro-phen-yl)acrylate. | Acta crystallographica. Section E, Structure reports online 20091001 |
A simplified green chemistry approaches to synthesis of 2-substituted 1,2,3-triazoles and 4-amino-5-cyanopyrazole derivatives conventional heating versus microwave and ultrasound as ecofriendly energy sources. | Ultrasonics sonochemistry 20090801 |
A novel and efficient one step synthesis of 2-amino-5-cyano-6-hydroxy-4-aryl pyrimidines and their anti-bacterial activity. | European journal of medicinal chemistry 20090601 |
Ethyl 3-amino-1-phenyl-1H-benzo[f]chromene-2-carboxyl-ate. | Acta crystallographica. Section E, Structure reports online 20090401 |
Synthesis of new 2-substituted pyrido[2,3-d]pyrimidin-4(1H)-ones and their antibacterial activity. | European journal of medicinal chemistry 20090301 |
Inorganic zinc salts catalyzed Knoevenagel condensation at room temperature without solvent. | Preparative biochemistry & biotechnology 20090101 |
Antiviral and antischistosomal evaluation of newly synthesized thioglycosides and their acyclic analogues. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20090101 |
Novel 3-(p-substituted phenyl)-6-bromo-4(3H)-quinazolinone derivatives of promising antiinflammatory and analgesic properties. | Acta poloniae pharmaceutica 20090101 |
Hydroxyapatite supported caesium carbonate as a new recyclable solid base catalyst for the Knoevenagel condensation in water. | Beilstein journal of organic chemistry 20090101 |
Ethyl 5-amino-3-methyl-sulfan-yl-1H-pyrazole-4-carboxyl-ate. | Acta crystallographica. Section E, Structure reports online 20081201 |
6,7-Dihydro-4-(4-methoxy-phen-yl)-3-methyl-6-oxo-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile. | Acta crystallographica. Section E, Structure reports online 20081001 |
4-(4-Bromo-phen-yl)-4,5,6,7-tetra-hydro-3-methyl-6-oxo-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile ethanol solvate. | Acta crystallographica. Section E, Structure reports online 20081001 |
Synthesis of new 3-pyridinecarboxylates of potential vasodilation properties. | European journal of medicinal chemistry 20080901 |
Synthesis and antimicrobial activity of some new pyrazole, fused pyrazolo[3,4-d]-pyrimidine and pyrazolo[4,3-e][1,2,4]-triazolo[1,5-c]pyrimidine derivatives. | Molecules (Basel, Switzerland) 20080729 |
Ethyl 5-acetyl-2-amino-4-methyl-thio-phene-3-carboxyl-ate. | Acta crystallographica. Section E, Structure reports online 20080601 |
Application of beta-(2-chloroaroyl) thioacetanilides in synthesis: an unusual and highly efficient access to thiochromeno[2,3-b]pyridine derivatives. | The Journal of organic chemistry 20080307 |
Ethyl 3'-cyano-1'-methyl-2-oxo-4'-phenylspiro-[acenaphthene-1,2'-pyrrolidine]-3'-carboxyl-ate. | Acta crystallographica. Section E, Structure reports online 20080201 |
Diethyl 5,5'-thio-bis[2-amino-4-(4-fluoro-phen-yl)-1-phenyl-1H-pyrrole-3-carboxyl-ate]. | Acta crystallographica. Section E, Structure reports online 20080101 |
Ethyl (E)-3-anilino-2-cyano-3-mercaptoacrylate. | Acta crystallographica. Section E, Structure reports online 20080101 |
An easy synthesis of 5-functionally substituted ethyl 4-amino-1-aryl- pyrazolo-3-carboxylates: interesting precursors to sildenafil analogues. | Beilstein journal of organic chemistry 20070101 |
Design, synthesis and pharmacological screening of a series of N1-(substituted) aryl-5,7-dimethyl-2-(substituted)pyrido(2,3-d)-pyrimidin-4(3H)-ones as potential histamine H1-receptor antagonists. | Journal of enzyme inhibition and medicinal chemistry 20061201 |
Synthesis of multisubstituted quinolines from Baylis-Hillman adducts obtained from substituted 2-chloronicotinaldehydes and their antimicrobial activity. | Bioorganic & medicinal chemistry 20060701 |
A new N-type organic semiconductor synthesized by knoevenagel condensation of truxenone and ethyl cyanoacetate. | Organic letters 20060608 |
Synthesis and molluscicidal activity of some 1,3,4-triaryl-5-chloropyrazole, pyrano[2,3-c]pyrazole, pyrazolylphthalazine and pyrano[2,3-d]thiazole derivatives. | Archiv der Pharmazie 20060601 |
ATR-IR spectroscopy of pendant NH2 groups on silica involved in the Knoevenagel condensation. | Langmuir : the ACS journal of surfaces and colloids 20060411 |
Synthesis and evaluation of 2,6-piperidinedione derivatives as potentially novel compounds with analgesic and other CNS activities. | Inflammopharmacology 20060301 |
Lanthanide(III) and Yttrium(III) Complexes of Benzimidazole-2-Acetic Acid: Synthesis, Characterisation and Effect of La(III) Complex on Germination of Wheat. | Bioinorganic chemistry and applications 20060101 |
Novel milrinone analogs of pyridine-3-carbonitrile derivatives as promising cardiotonic agents. | European journal of medicinal chemistry 20051201 |
Synthesis and antiviral activity of novel chiral cyanoacrylate derivatives. | Journal of agricultural and food chemistry 20051005 |
Synthesis, tautomeric states and crystal structure of (Z)-ethyl 2-cyano-2-(3H-quinazoline-4-ylidene) acetate and (Z)-ethyl 2-cyano-2-(2-methyl-3H-quinazoline-4-ylidene) acetate. | Molecules (Basel, Switzerland) 20050930 |
Synthesis of 1,1-disubstituted-2,6-diarylcyclohexane-4-ones catalyzed by KF/basic Al2O3 under ultrasound. | Ultrasonics sonochemistry 20050801 |
Direct organocatalytic and highly enantio- and diastereoselective Mannich reactions of alpha-substituted alpha-cyanoacetates. | Angewandte Chemie (International ed. in English) 20050506 |
Knoevenagel reaction in water catalyzed by amine supported on silica gel. | Molecular diversity 20050101 |
Highly efficient and mild copper-catalyzed N- and C-arylations with aryl bromides and iodides. | Chemistry (Weinheim an der Bergstrasse, Germany) 20041105 |
Microwave assisted synthesis of 2-(4-substituted piperazin-1-yl)-1,8-naphthyridine-3-carbonitrile as a new class of serotonin 5-HT3 receptor antagonists. | Bioorganic & medicinal chemistry letters 20041018 |
Solvent-free reactions of C60 with active methylene compounds, either with or without carbon tetrabromide, in the presence of bases under high-speed vibration milling conditions. | Organic & biomolecular chemistry 20040621 |
Selective addition to [60]fullerene of two different radicals generated from Mn(III)-based radical reaction. | Organic & biomolecular chemistry 20040421 |
Synthesis and some reactions of 3-chloro-2-(cyanomethylene)-1,2-dihydroquinoxalines. | Molecules (Basel, Switzerland) 20040331 |
Synthesis and biological testing of novel analogues of sydnone as potential antibacterial agents. | Archiv der Pharmazie 20040301 |
Reaction of [60]fullerene with free radicals generated from active methylene compounds by manganese(III) acetate dihydrate. | Organic & biomolecular chemistry 20031221 |
Synthesis of some new thiazole derivatives of pharmaceutical interest. | Bollettino chimico farmaceutico 20031101 |
P(i-BuNCH2CH2)3N: an efficient ligand for the direct alpha-arylation of nitriles with aryl bromides. | The Journal of organic chemistry 20031017 |
Electrophilicity parameters for benzylidenemalononitriles. | The Journal of organic chemistry 20030905 |
Ultrasound promoted synthesis of 2-aroyl-1,3,5-triaryl-4-carbethoxy-4-cyanocyclohexanols. | Ultrasonics sonochemistry 20030501 |
Synthesis and properties of new substituted 1,2,4-triazoles: potential antitumor agents. | Bioorganic & medicinal chemistry 20030417 |
Synthesis and cytotoxicity evaluation of 2-amino- and 2-hidroxy-3-ethoxycarbonyl-N-substituted-benzo[f]indole-4,9-dione derivatives. | Bioorganic & medicinal chemistry 20030403 |
Synthesis of 5-substituted 2-methylbenzimidazoles with anticancer activity. | Archiv der Pharmazie 20030301 |
Synthesis of vanillin ethers from 4-(bromomethyl) coumarins as anti-inflammatory agents. | European journal of medicinal chemistry 20030301 |
Knoevenagel condensation reaction in a membrane microreactor. | Chemical communications (Cambridge, England) 20030121 |
Non-classical antifolates, 5-(N-phenylpyrrolidin-3-yl)-2,4,6-triaminopyrimidines and 2,4-Diamino-6(5H)-oxopyrimidines, synthesis and antitumor studies. | Bioorganic & medicinal chemistry 20030102 |
A one-pot microwave-assisted synthesis of pyrido[2,3-d]pyrimidines. | Molecular diversity 20030101 |
Synthesis and antibacterial activity of fused 1, 2, 4-triazolo[4, 3-a]quinoxaline and oxopyrimido[2', 1':5, 1]-1, 2, 4-triazolo[4, 3-a]quinoxaline derivatives. | Archiv der Pharmazie 20020801 |
Synthesis of ethyl alpha-cyanocinnamates catalyzed by KF-Al2O3 under ultrasound irradiation. | Ultrasonics sonochemistry 20020701 |
Pyrido[2, 3-d]pyrimidines and pyrimido[5',4':5, 6]pyrido[2, 3-d]pyrimidines as new antiviral agents: synthesis and biological activity. | Archiv der Pharmazie 20020601 |
Pyrrolo[2,1-c][1,2,4]triazines from 2-diazopyrroles: synthesis and antiproliferative activity. | European journal of medicinal chemistry 20020301 |
Palladium-catalyzed arylation of malonates and cyanoesters using sterically hindered trialkyl- and ferrocenyldialkylphosphine ligands. | The Journal of organic chemistry 20020125 |
Synthesis of 1-(2-naphthylsulfonyl)pyrazole-C-glycosides. | Nucleosides, nucleotides & nucleic acids 20020101 |
Palladium-catalyzed arylation of ethyl cyanoacetate. Fluorescence resonance energy transfer as a tool for reaction discovery. | Journal of the American Chemical Society 20010516 |
Synthesis of ethyl alkylidene alpha cyanoacetates under ultrasound irradiation. | Ultrasonics sonochemistry 20010401 |