Preparation and antimicrobial activity of some carboxymethyl chitosan acyl thiourea derivatives.

International journal of biological macromolecules 20120601

The effect of aprepitant and race on the pharmacokinetics of cyclophosphamide in breast cancer patients.

Cancer chemotherapy and pharmacology 20120501

Reverse thioether ligation route to multimeric peptide antigens.

Organic & biomolecular chemistry 20120421

A sensitive HPLC-based method to quantify adenine nucleotides in primary astrocyte cell cultures.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120315

Anticancer activity of stabilized palifosfamide in vivo: schedule effects, oral bioavailability, and enhanced activity with docetaxel and doxorubicin.

Anti-cancer drugs 20120201

Factor-independent transcription pausing caused by recognition of the RNA-DNA hybrid sequence.

The EMBO journal 20120201

Sensor-based cell and tissue screening for personalized cancer chemotherapy.

Medical & biological engineering & computing 20120201

Liquid chromatography-tandem mass spectrometry quantification of 6-thioguanine in DNA using endogenous guanine as internal standard.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120115

Identification of 3,N(4)-etheno-5-methyl-2'-deoxycytidine in human DNA: a new modified nucleoside which may perturb genome methylation.

Chemical research in toxicology 20120113

Chitosan microparticles and nanoparticles as biocompatible delivery vehicles for peptide and protein-based immunocontraceptive vaccines.

Molecular pharmaceutics 20120101

Defects in leaf carbohydrate metabolism compromise acclimation to high light and lead to a high chlorophyll fluorescence phenotype in Arabidopsis thaliana.

BMC plant biology 20120101

Contrasting cellularity and fatty acid composition in fat depots from Alentejana and Barrosã bovine breeds fed high and low forage diets.

International journal of biological sciences 20120101

2-Chloro-1-[4-(2,4-difluoro-benz-yl)piperazin-1-yl]ethanone.

Acta crystallographica. Section E, Structure reports online 20120101

Elucidation of the involvement of p14, a sperm protein during maturation, capacitation and acrosome reaction of caprine spermatozoa.

PloS one 20120101

Novel AlkB dioxygenases--alternative models for in silico and in vivo studies.

PloS one 20120101

Busulphan-cyclophosphamide cause endothelial injury, remodeling of resistance arteries and enhanced expression of endothelial nitric oxide synthase.

PloS one 20120101

Use of Linear Free Energy Relationships (LFERs) to elucidate the mechanisms of reaction of a γ-methyl-β-alkynyl and an ortho-substituted aryl chloroformate ester.

International journal of molecular sciences 20120101

Sesquiterpenes from an Egyptian herbal medicine, Pulicaria undulate, with inhibitory effects on nitric oxide production in RAW264.7 macrophage cells.

Chemical & pharmaceutical bulletin 20120101

Structure-based classification and ontology in chemistry.

Journal of cheminformatics 20120101

Plastics and carcinogenesis: The example of vinyl chloride.

Journal of carcinogenesis 20120101

Identification and characterisation of a novel acylpeptide hydrolase from Sulfolobus solfataricus: structural and functional insights.

PloS one 20120101

Inhibition of gene expression of organic cation/carnitine transporter and antioxidant enzymes in oxazaphosphorines-induced acute cardiomyopathic rat models.

Oxidative medicine and cellular longevity 20120101

Determination of cellular aminopropyltransferase activity using precolumn fluorescent etheno-derivatization with high-performance liquid chromatography.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20120101

Efficient and selective removal of chloroacetyl group promoted with tetra-n-butylammonium fluoride (TBAF).

Carbohydrate research 20111213

Fatal Ifosfamide-induced metabolic encephalopathy in patients with recurrent epithelial ovarian cancer: report of two cases.

Cancer research and treatment : official journal of Korean Cancer Association 20111201

Cysteine cyclic pyrrole-imidazole polyamide for sequence-specific recognition in the DNA minor groove.

Journal of the American Chemical Society 20111123

6-Bromo-imidazo[1,2-a]pyridin-8-amine.

Acta crystallographica. Section E, Structure reports online 20111101

Peptide dendrimer enzyme models for ester hydrolysis and aldolization prepared by convergent thioether ligation.

Organic & biomolecular chemistry 20111021

One-pot synthesis of chiral aziridines by a domino reaction by using desulfonylative formation on the N-tosyl imine of chloroacetaldehyde with an asymmetric Mannich reaction as a key step.

Chemistry (Weinheim an der Bergstrasse, Germany) 20111010

Synthesis of β-(1→6)-linked N-acetyl-D-glucosamine oligosaccharide substrates and their hydrolysis by Dispersin B.

Carbohydrate research 20110906

2,4-Dioxo-1-(prop-2-yn-yl)-1,2,3,4-tetra-hydro-pyrimidine-5-carbaldehyde.

Acta crystallographica. Section E, Structure reports online 20110901

Equilibrative nucleoside transporter 1 (ENT1) is critical for pollen germination and vegetative growth in Arabidopsis.

Journal of experimental botany 20110801

1,N2-Etheno-2'-deoxyguanosine adopts the syn conformation about the glycosyl bond when mismatched with deoxyadenosine.

Chemical research in toxicology 20110718

(5R)-3-(2-Chloro-acet-yl)-4-methyl-5-phenyl-1,3,4-oxadiazinan-2-one.

Acta crystallographica. Section E, Structure reports online 20110701

Insulin restores gestational diabetes mellitus-reduced adenosine transport involving differential expression of insulin receptor isoforms in human umbilical vein endothelium.

Diabetes 20110601

Estrogenic activity of chemical constituents from Tephrosia candida.

Journal of natural products 20110527

The role of AlkB protein in repair of 1,N⁶-ethenoadenine in Escherichia coli cells.

Mutagenesis 20110501

Effects of chloroacetaldehyde in 2-chloroethanol-induced cardiotoxicity.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110501

One-pot synthesis of chiral α-substituted β,γ-epoxy aldehyde derivatives through an asymmetric aldol reaction of chloroacetaldehyde.

Angewandte Chemie (International ed. in English) 20110314

Platelet receptor polymorphisms do not influence Staphylococcus aureus-platelet interactions or infective endocarditis.

Microbes and infection 20110301

Bactericidal activity of porcine neutrophil secretions.

Veterinary immunology and immunopathology 20110215

Design, synthesis and antimycobacterial activities of 1-methyl-2-alkenyl-4(1H)-quinolones.

Bioorganic & medicinal chemistry 20110101

Therapeutic approaches to delay the onset of Alzheimer's disease.

Journal of aging research 20110101

A trypsin-like serine protease is involved in pseudorabies virus invasion through the basement membrane barrier of porcine nasal respiratory mucosa.

Veterinary research 20110101

Acute liver toxicity with ifosfamide in the treatment of sarcoma: a case report.

Journal of medical case reports 20110101

Nitric oxide-induced activation of the AMP-activated protein kinase α2 subunit attenuates IκB kinase activity and inflammatory responses in endothelial cells.

PloS one 20110101

Use of specific chemical reagents for detection of modified nucleotides in RNA.

Journal of nucleic acids 20110101

Mechanism of heparin acceleration of tissue inhibitor of metalloproteases-1 (TIMP-1) degradation by the human neutrophil elastase.

PloS one 20110101

Adaptation of Rhizobium leguminosarum to pea, alfalfa and sugar beet rhizospheres investigated by comparative transcriptomics.

Genome biology 20110101

Comparative analyses of exoproteinases produced by three phytopathogenic microorganisms.

Journal of pathogens 20110101

A review on phytochemistry and medicinal properties of the genus Achillea.

Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101

Glutathione s-transferases in pediatric cancer.

Frontiers in oncology 20110101

Furano-1,2-naphthoquinone inhibits EGFR signaling associated with G2/M cell cycle arrest and apoptosis in A549 cells.

Cell biochemistry and function 20101202

Reversible proximal renal tubular dysfunction after one-time Ifosfamide exposure.

Cancer research and treatment : official journal of Korean Cancer Association 20101201

Tissue Factor/Factor FVII Complex Inhibitors in Cardiovascular Disease. Are Things Going Well?

Current cardiology reviews 20101101

Kinetics and mechanism of the atmospheric reactions of atomic chlorine with 1-penten-3-ol and (Z)-2-penten-1-ol: an experimental and theoretical study.

Physical chemistry chemical physics : PCCP 20101014

Comparative metabolism of cyclophosphamide and ifosfamide in the mouse using UPLC-ESI-QTOFMS-based metabolomics.

Biochemical pharmacology 20101001

Synthesis, characterization, and antifungal activity of novel quaternary chitosan derivatives.

Carbohydrate research 20100903

The synthesis, X-ray crystal structure and optical properties of novel 1-ferrocenyl-2-(3-phenyl-1H-1,2,4-triazol-5-ylthio)ethanone derivatives.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100901

Assessment of heterologous butyrate and butanol pathway activity by measurement of intracellular pathway intermediates in recombinant Escherichia coli.

Applied microbiology and biotechnology 20100901

PI3Kα inhibitors that inhibit metastasis.

Oncotarget 20100901

1-Chloro-acetyl-2,6-bis-(2-chloro-phen-yl)-3,5-dimethyl-piperidin-4-one.

Acta crystallographica. Section E, Structure reports online 20100901

Human base excision repair creates a bias toward -1 frameshift mutations.

The Journal of biological chemistry 20100813

Oxazaphosphorines: new therapeutic strategies for an old class of drugs.

Expert opinion on drug metabolism & toxicology 20100801

Synthesis and anticancer activity of novel betulinic acid and betulin derivatives.

Archiv der Pharmazie 20100801

Thorpe-Ingold acceleration of oxirane formation is mostly a solvent effect.

Journal of the American Chemical Society 20100630

Naphtho[1,2-b]furan-4,5-dione induces apoptosis of oral squamous cell carcinoma: involvement of EGF receptor/PI3K/Akt signaling pathway.

European journal of pharmacology 20100625

Protective effects of fomepizole on 2-chloroethanol toxicity.

Human & experimental toxicology 20100601

Naphtho[1,2-b]furan-4,5-dione disrupts Janus kinase-2 and induces apoptosis in breast cancer MDA-MB-231 cells.

Toxicology in vitro : an international journal published in association with BIBRA 20100601

The execution phase of autophagy associated PCD during insect metamorphosis.

Apoptosis : an international journal on programmed cell death 20100601

Different hydrogen-bonding modes in two closely related oximes.

Acta crystallographica. Section C, Crystal structure communications 20100601

1-(2-Bromo-acet-yl)-3-methyl-2,6-diphenyl-piperidin-4-one.

Acta crystallographica. Section E, Structure reports online 20100601

1-Chloro-acetyl-2,6-bis-(2-chloro-phen-yl)-3,5-dimethyl-piperidin-4-one oxime.

Acta crystallographica. Section E, Structure reports online 20100601

First principles insight into the alpha-glucan structures of starch: their synthesis, conformation, and hydration.

Chemical reviews 20100414

Ifosfamide metabolite chloroacetaldehyde inhibits cell proliferation and glucose metabolism without decreasing cellular ATP content in human breast cancer cells MCF-7.

Journal of applied toxicology : JAT 20100401

Kinetics and mechanism of chlorine-atom-initiated oxidation of allyl alcohol, 3-buten-2-ol, and 2-methyl-3-buten-2-ol.

The journal of physical chemistry. A 20100401

Comparison of the novel HK-2 human renal proximal tubular cell line with the standard LLC-PK1 cell line in studying drug-induced nephrotoxicity.

Canadian journal of physiology and pharmacology 20100401

Structure of the 1,N(2)-etheno-2'-deoxyguanosine lesion in the 3'-G(epsilon dG)T-5' sequence opposite a one-base deletion.

Biochemistry 20100330

Vasorelaxant effects of extracts of the stem bark of Terminalia superba Engler & Diels (Combretaceae).

Journal of ethnopharmacology 20100203

Chloroacetaldehyde-induced mutagenesis in Escherichia coli: the role of AlkB protein in repair of 3,N(4)-ethenocytosine and 3,N(4)-alpha-hydroxyethanocytosine.

Mutation research 20100203

Environmentally relevant parameters affecting PCB degradation: carbon source- and growth phase-mitigated effects of the expression of the biphenyl pathway and associated genes in Burkholderia xenovorans LB400.

Biodegradation 20100201

Targets of chloroacetaldehyde-induced nephrotoxicity.

Toxicology in vitro : an international journal published in association with BIBRA 20100201

Naphtho[1,2-b]furan-4,5-dione induces apoptosis and S-phase arrest of MDA-MB-231 cells through JNK and ERK signaling activation.

Toxicology in vitro : an international journal published in association with BIBRA 20100201

1-Chloro-acetyl-3-isopropyl-r-2,c-6-diphenyl-piperidin-4-one.

Acta crystallographica. Section E, Structure reports online 20100201

Naphtho[1,2-b]furan-4,5-dione inactivates EGFR and PI3K/Akt signaling pathways in human lung adenocarcinoma A549 cells.

Life sciences 20100130

Comparative study of the dissociative ionization of 1,1,1-trichloroethane using nanosecond and femtosecond laser pulses.

International journal of molecular sciences 20100101

Adenosine thiamine triphosphate accumulates in Escherichia coli cells in response to specific conditions of metabolic stress.

BMC microbiology 20100101

Removal of urothelium affects bladder contractility and release of ATP but not release of NO in rat urinary bladder.

BMC urology 20100101

Use of empirical correlations to determine solvent effects in the solvolysis of S-methyl chlorothioformate.

International journal of molecular sciences 20100101

Analysis of the nucleophilic solvation effects in isopropyl chlorothioformate solvolysis.

International journal of molecular sciences 20100101

Genetic variations in human glutathione transferase enzymes: significance for pharmacology and toxicology.

Human genomics and proteomics : HGP 20100101

Repair of DNA Alkylation Damage by the Escherichia coli Adaptive Response Protein AlkB as Studied by ESI-TOF Mass Spectrometry.

Journal of nucleic acids 20100101

Formation and repair of tobacco carcinogen-derived bulky DNA adducts.

Journal of nucleic acids 20100101

Methylene blue: revisited.

Journal of anaesthesiology, clinical pharmacology 20100101

Mouse plasminogen has oxidized phosphatidylcholine adducts that are not metabolized by lipoprotein-associated phospholipase A₂under basal conditions.

International journal of molecular sciences 20100101

[Determination of 5 polyether antibiotics in chicken tissues by liquid chromatography-electrospray ionization tandem mass spectrometry].

Se pu = Chinese journal of chromatography 20091101

1-Chloro-acetyl-r-2,c-6-bis-(4-methoxy-phen-yl)-c-3,t-3-dimethyl-piperidin-4-one.

Acta crystallographica. Section E, Structure reports online 20091101

1-Chloro-acetyl-r-2,c-6-bis-(4-methoxy-phen-yl)-t-3-methyl-piperidin-4-one.

Acta crystallographica. Section E, Structure reports online 20091101

N(alpha)-tosyl-L-phenylalanine chloromethyl ketone induces caspase-dependent apoptosis in transformed human B cell lines with transcriptional down-regulation of anti-apoptotic HS1-associated protein X-1.

The Journal of biological chemistry 20091009

5-Chloro-acetyl-4-methyl-2,3,4,5-tetra-hydro-1H-1,5-benzodiazepin-2-one.

Acta crystallographica. Section E, Structure reports online 20091001

Preclinical activity of palifosfamide lysine (ZIO-201) in pediatric sarcomas including oxazaphosphorine-resistant osteosarcoma.

Cancer chemotherapy and pharmacology 20090901

1-Chloro-acetyl-2,6-bis-(2-methoxy-phen-yl)-3,5-dimethyl-piperidin-4-one.

Acta crystallographica. Section E, Structure reports online 20090901

1-Chloro-acetyl-2,6-bis-(3-fluoro-phen-yl)piperidin-4-one.

Acta crystallographica. Section E, Structure reports online 20090801

Detection and quantification of (R) and (S)-dechloroethylifosfamide metabolites in plasma from children by enantioselective LC/MS/MS.

Chirality 20090701

SAM levels, gene expression of SAM synthetase, methionine synthase and ACC oxidase, and ethylene emission from N. suaveolens flowers.

Plant molecular biology 20090701

Ifosfamide nephrotoxicity in children: a mechanistic base for pharmacological prevention.

Expert opinion on drug safety 20090301

Grunwald-Winstein analysis: isopropyl chloroformate solvolysis revisited.

International journal of molecular sciences 20090301

Oxidation and glycolytic cleavage of etheno and propano DNA base adducts.

Biochemistry 20090203

New ifosfamide analogs designed for lower associated neurotoxicity and nephrotoxicity with modified alkylating kinetics leading to enhanced in vitro anticancer activity.

The Journal of pharmacology and experimental therapeutics 20090201

Synthesis and chemoselective intramolecular crosslinking of a HER2-binding affibody.

Biopolymers 20090101

Conformational effects of a common codon 751 polymorphism on the C-terminal domain of the xeroderma pigmentosum D protein.

Journal of carcinogenesis 20090101

Protective effect of transgenic expression of porcine heat shock protein 70 on hypothalamic ischemic and oxidative damage in a mouse model of heatstroke.

BMC neuroscience 20090101

Effect of the XRCC1 codon 399 polymorphism on the repair of vinyl chloride metabolite-induced DNA damage.

Journal of carcinogenesis 20090101

Ifosfamide may be safely used in patients with end stage renal disease on hemodialysis.

Sarcoma 20090101

Rhodium-complex-catalyzed addition reactions of chloroacetyl chlorides to alkynes.

Organic letters 20081204

Extended Grunwald-Winstein analysis - LFER used to gauge solvent effects in p-nitrophenyl chloroformate solvolysis.

International journal of molecular sciences 20081101

1-Bromo-acetyl-2,6-bis-(4-methoxy-phen-yl)-3,5-dimethyl-piperidin-4-one.

Acta crystallographica. Section E, Structure reports online 20081001

Structure of the 1,N2-ethenodeoxyguanosine adduct opposite cytosine in duplex DNA: Hoogsteen base pairing at pH 5.2.

Chemical research in toxicology 20080915

Chiral NHC-catalyzed oxodiene Diels-Alder reactions with alpha-chloroaldehyde bisulfite salts.

Organic letters 20080904

Mechanisms of the ifosfamide-induced inhibition of endocytosis in the rat proximal kidney tubule.

Archives of toxicology 20080901

The broad-spectrum caspase inhibitor Boc-Asp-CMK induces cell death in human leukaemia cells.

Toxicology in vitro : an international journal published in association with BIBRA 20080801

Selective alkylation of beta(II)-tubulin and thioredoxin-1 by structurally related subsets of aryl chloroethylureas leading to either anti-microtubules or redox modulating agents.

Bioorganic & medicinal chemistry 20080801

Engineering a catabolic pathway in plants for the degradation of 1,2-dichloroethane.

Plant physiology 20080701

Ribosomal synthesis of bicyclic peptides via two orthogonal inter-side-chain reactions.

Journal of the American Chemical Society 20080611

Calcium-dependent release of adenosine and uridine nucleotides from A549 cells.

Purinergic signalling 20080601

AlkB homologue 2-mediated repair of ethenoadenine lesions in mammalian DNA.

Cancer research 20080601

Halogenated derivatives QSAR model using spectral moments to predict haloacetic acids (HAA) mutagenicity.

Bioorganic & medicinal chemistry 20080515

Ribosomal synthesis of peptidase-resistant peptides closed by a nonreducible inter-side-chain bond.

ACS chemical biology 20080418

In vivo mesna and amifostine do not prevent chloroacetaldehyde nephrotoxicity in vitro.

Pediatric nephrology (Berlin, Germany) 20080401

Determination of leukocyte DNA 6-thioguanine nucleotide levels by high-performance liquid chromatography with fluorescence detection.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080315

Yeast Polo-like kinase substrates are nailed with the right tools.

Genome biology 20080101

A novel bioluminescent protease assay using engineered firefly luciferase.

Current chemical genomics 20080101

Synthesis and NMR spectral studies of N-chloroacetyl-2,6-diarylpiperidin-4-ones.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20071231

Influence of short-term use of dexamethasone on the pharmacokinetics of ifosfamide in patients.

Drug metabolism and disposition: the biological fate of chemicals 20071001

Repression by binding of H-NS within the transcription unit.

The Journal of biological chemistry 20070810

Role of MGMT in protecting against cyclophosphamide-induced toxicity in cells and animals.

DNA repair 20070801

AlkB influences the chloroacetaldehyde-induced mutation spectra and toxicity in the pSP189 supF shuttle vector.

Chemical research in toxicology 20070801

The effect of N-acetylcysteine on ifosfamide-induced nephrotoxicity: in vitro studies in renal tubular cells.

Translational research : the journal of laboratory and clinical medicine 20070701

Mesna or cysteine prevents chloroacetaldehyde-induced cell death of human proximal tubule cells.

Pediatric nephrology (Berlin, Germany) 20070601

Necrotic pathway in human osteosarcoma Saos-2 cell death induced by chloroacetaldehyde.

Anti-cancer drugs 20070601

Role of O6-methylguanine-DNA methyltransferase in protecting from alkylating agent-induced toxicity and mutations in mice.

Carcinogenesis 20070501

[14C]bis(2-chloroethoxy)methane: comparative absorption, distribution, metabolism and excretion in rats and mice.

Xenobiotica; the fate of foreign compounds in biological systems 20070401

Ifosfamide toxicity in cultured proximal renal tubule cells.

Pediatric nephrology (Berlin, Germany) 20070301

The chloromethylketone protease inhibitor AAPF(CMK) also targets ATP-dependent helicases and SAP-domain proteins.

Journal of cellular biochemistry 20070215

Osteomalacia as a late metabolic complication of Ifosfamide chemotherapy in young adults: illustrative cases and review of the literature.

Sarcoma 20070101

Occurrence, genotoxicity, and carcinogenicity of regulated and emerging disinfection by-products in drinking water: a review and roadmap for research.

Mutation research 20070101

Activity-based substrate profiling for Gcn5-related N-acetyltransferases: the use of chloroacetyl-coenzyme A to identify protein substrates.

Journal of the American Chemical Society 20061206

Selective thiourea optical probe based on thiourea-induced removal of chloroacetyl group from chloroacetylamine.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20061201

Thiol-mediated anchoring of ligands to self-assembled monolayers for studies of biospecific interactions.

Langmuir : the ACS journal of surfaces and colloids 20061121

Ifosfamide metabolites CAA, 4-OH-Ifo and Ifo-mustard reduce apical phosphate transport by changing NaPi-IIa in OK cells.

Kidney international 20061101

Synthesis of 2-alkenyl-3-(alkoxycarbonyl)furans based on Feist-Benary cyclocondensation of (2,4-dioxobutylidene)phosphoranes with alpha-haloketones and alpha-chloracetaldehyde.

The Journal of organic chemistry 20061013

Selective alteration of the rate-limiting step in cytosolic aldehyde dehydrogenase through random mutagenesis.

Biochemistry 20060808

Ifosfamide-induced nephrotoxicity: mechanism and prevention.

Cancer research 20060801

Efficient method for the deprotection of tert-butyldimethylsilyl ethers with TiCl4-Lewis base complexes: application to the synthesis of 1beta-methylcarbapenems.

The Journal of organic chemistry 20060707

Enantioselective metabolism of ifosfamide by the kidney.

Chirality 20060601

Ifosfamide: pharmacokinetic properties for central nervous system metastasis prevention.

Annals of oncology : official journal of the European Society for Medical Oncology 20060501

Peptides containing acylated C-terminal gem diamines: novel irreversible inactivators of the cysteine and serine proteinases.

Chemical biology & drug design 20060501

Directed evolution of an industrial biocatalyst: 2-deoxy-D-ribose 5-phosphate aldolase.

Biotechnology journal 20060501

Systematic synthesis of bisubstrate-type inhibitors of N-acetylglucosaminyltransferases.

Chemistry (Weinheim an der Bergstrasse, Germany) 20060424

Insights into the hydrogen-abstraction reactions of diol dehydratase: relevance to the catalytic mechanism and suicide inactivation.

Journal of the American Chemical Society 20060315

A new protein superfamily includes two novel 3-methyladenine DNA glycosylases from Bacillus cereus, AlkC and AlkD.

Molecular microbiology 20060301

Chloroacetaldehyde: mode of antitumor action of the ifosfamide metabolite.

Cancer chemotherapy and pharmacology 20060201

Hydroxyl-terminated dendritic oligomers from bile acids: synthesis and properties.

The Journal of organic chemistry 20060120

Chloroacetaldehyde- and acrolein-induced death of human proximal tubule cells.

Pediatric nephrology (Berlin, Germany) 20060101

Sequence-specific p53 gene damage by chloroacetaldehyde and its repair kinetics in Escherichia coli.

Acta biochimica Polonica 20060101

Application of biological activated carbon anaerobic reactor for treatment of hazardous chemicals.

Water science and technology : a journal of the International Association on Water Pollution Research 20060101

Chloroacetaldehyde as a sulfhydryl reagent: the role of critical thiol groups in ifosfamide nephropathy.

Kidney & blood pressure research 20060101

Disturbed Ca2+-signaling by chloroacetaldehyde: a possible cause for chronic ifosfamide nephrotoxicity.

Kidney international 20051101

Site specific synthesis and polymerase bypass of oligonucleotides containing a 6-hydroxy-3,5,6,7-tetrahydro-9H-imidazo[1,2-a]purin-9-one base, an intermediate in the formation of 1,N2-etheno-2'-deoxyguanosine.

Chemical research in toxicology 20051101

Mechanisms of solvolyses of acid chlorides and chloroformates. Chloroacetyl and phenylacetyl chloride as similarity models.

The Journal of organic chemistry 20051028

Dynamic analysis of metabolic effects of chloroacetaldehyde and cytochalasin B on tumor cells using bioelectronic sensor chips.

Journal of cancer research and clinical oncology 20051001

AlkB reverses etheno DNA lesions caused by lipid oxidation in vitro and in vivo.

Nature structural & molecular biology 20051001

Enantioselective metabolism and cytotoxicity of R-ifosfamide and S-ifosfamide by tumor cell-expressed cytochromes P450.

Drug metabolism and disposition: the biological fate of chemicals 20050901

Synthesis, characterisation and theoretical calculations of 2,6-diaminopurine etheno derivatives.

Organic & biomolecular chemistry 20050821

Palladium-catalyzed regioselective arylation of imidazo[1,2-b][1,2,4]triazine: synthesis of an alpha 2/3-selective GABA agonist.

The Journal of organic chemistry 20050722

Contribution of CYP3A5 to hepatic and renal ifosfamide N-dechloroethylation.

Drug metabolism and disposition: the biological fate of chemicals 20050701

Cytochrome P450 3A and 2B6 in the developing kidney: implications for ifosfamide nephrotoxicity.

Pediatric nephrology (Berlin, Germany) 20050701

Differential effects of Mg2+ ions on the individual kinetic steps of human cytosolic and mitochondrial aldehyde dehydrogenases.

Biochemistry 20050607

A tubule cell model for ifosfamide nephrotoxicity.

Canadian journal of physiology and pharmacology 20050601

Exocyclic DNA lesions stimulate DNA cleavage mediated by human topoisomerase II alpha in vitro and in cultured cells.

Biochemistry 20050315

Matrix isolation and theoretical study of the photochemical reaction of CrCl2O2 with chloroethenes.

The journal of physical chemistry. A 20050210

One-step synthesis of labeled sugar nucleotides for protein O-GlcNAc modification studies by chemical function analysis of an archaeal protein.

Journal of the American Chemical Society 20050126

Mismatch dependent uracil/thymine-DNA glycosylases excise exocyclic hydroxyethano and hydroxypropano cytosine adducts.

Acta biochimica Polonica 20050101

[Optimization of transfection properties of DNA-lysine dendrimer complexes].

Bioorganicheskaia khimiia 20050101

Ifosfamide-induced encephalopathy with or without using methylene blue.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20050101

ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversal.

Cancer cell international 20050101

Polymorphisms of DNA repair gene XPD and DNA damage of workers exposed to vinylchloride monomer.

International journal of hygiene and environmental health 20050101

[Increased urinary excretion of the neurotoxic side-chain metabolites of ifosphamide in children with polymorphism of the glutathione S-transferases genes].

Medycyna wieku rozwojowego 20050101

DNA damage and mutations produced by chloroacetaldehyde in a CpG-methylated target gene.

Mutation research 20041221

Role of mismatch-specific uracil-DNA glycosylase in repair of 3,N4-ethenocytosine in vivo.

DNA repair 20041202

Degradation pathway of 2-chloroethanol in Pseudomonas stutzeri strain JJ under denitrifying conditions.

Archives of microbiology 20041201

Analysis of drug action on tumor cell metabolism using electronic sensor chips.

Archiv der Pharmazie 20041201

Renal ontogeny of ifosfamide nephrotoxicity.

The Journal of laboratory and clinical medicine 20041201

Release of beta-nicotinamide adenine dinucleotide upon stimulation of postganglionic nerve terminals in blood vessels and urinary bladder.

The Journal of biological chemistry 20041119

Suicide inactivation of dioldehydratase by glycolaldehyde and chloroacetaldehyde: an examination of the reaction mechanism.

Journal of the American Chemical Society 20041006

Increased risk of hepatocellular carcinoma and liver cirrhosis in vinyl chloride workers: synergistic effect of occupational exposure with alcohol intake.

Environmental health perspectives 20040801

Dissociation of the ground state vinoxy radical and its photolytic precursor chloroacetaldehyde: electronic nonadiabaticity and the suppression of the H+ketene channel.

The Journal of chemical physics 20040722

Phase I and pharmacokinetic study of the combination of topotecan and ifosfamide administered intravenously every 3 weeks.

British journal of cancer 20040614

Role of nucleotide- and base-excision repair in genotoxin-induced neuronal cell death.

DNA repair 20040603

S-Adenosyl methionine/S-adenosyl-L-homocysteine ratio determination by capillary electrophoresis employed as a monitoring tool for the antiviral effectiveness of adenosine analogs.

Electrophoresis 20040601

Activation of the anticancer prodrugs cyclophosphamide and ifosfamide: identification of cytochrome P450 2B enzymes and site-specific mutants with improved enzyme kinetics.

Molecular pharmacology 20040501

Factor VII-activating protease (FSAP) inhibits growth factor-mediated cell proliferation and migration of vascular smooth muscle cells.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040401

New nucleoside analogs from 2-amino-9-(beta-D-ribofuranosyl)purine.

Organic & biomolecular chemistry 20040321

Renal-tubule metabolism of ifosfamide to the nephrotoxic chloroacetaldehyde: pharmacokinetic modeling for estimation of intracellular levels.

The Journal of laboratory and clinical medicine 20040301

CYP3A4, CYP2C9 and CYP2B6 expression and ifosfamide turnover in breast cancer tissue microsomes.

British journal of cancer 20040223

[Chips instead of mice: cells on bioelectronic sensor-chips as an alternative to animal experiments].

ALTEX 20040101

The over-representation of binary DNA tracts in seven sequenced chromosomes.

BMC genomics 20040101

Functional cellular assays with multiparametric silicon sensor chips.

Lab on a chip 20031101

Selective enhancement of ifosfamide-induced toxicity in Chinese hamster ovary cells.

Cancer chemotherapy and pharmacology 20031001

Comparative toxicity of ifosfamide metabolites and protective effect of mesna and amifostine in cultured renal tubule cells.

Toxicology in vitro : an international journal published in association with BIBRA 20030801

Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity.

Cell death and differentiation 20030801

Photocatalytic oxidation of gaseous 2-chloroethyl ethyl sulfide over TiO2.

Environmental science & technology 20030801

Liquid chromatographic assay for the antiviral nucleotide analogue tenofovir in plasma using derivatization with chloroacetaldehyde.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030705

Regioselective synthesis of 1,N(2)-etheno-2'-deoxyguanosine and its generation in oligomeric DNA.

Chemical research in toxicology 20030601

Determination of tenofovir in human plasma by high-performance liquid chromatography with spectrofluorimetric detection.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030305

A facile preparation of 1-(6-hydroxyindol-1-yl)-2,2-dimethylpropan-1-one.

Chemical & pharmaceutical bulletin 20030101

Multiparametric sensor chips for chemosensitivity testing of sensitive and resistant tumor cells.

Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20030101

Microphysiological testing for chemosensitivity of living tumor cells with multiparametric microsensor chips.

Cancer detection and prevention 20030101

Pharmacology of ifosfamide.

Oncology 20030101

Neurological toxicity of ifosfamide.

Oncology 20030101

Synthesis and comparison of antibody recognition of conjugates containing herpes simplex virus type 1 glycoprotein D epitope VII.

Bioconjugate chemistry 20030101

Cytoprotective and anticancer properties of coenzyme Q versus capsaicin.

BioFactors (Oxford, England) 20030101

Tag-reporter and resin capture--release strategy in oligosaccharide synthesis.

Chemistry (Weinheim an der Bergstrasse, Germany) 20020715

High-performance liquid chromatographic technique for detection of a fluorescent analogue of ADP-ribose in isolated blood vessel preparations.

Analytical biochemistry 20020615

[Development of novel methodology for rapid conjugated oligosaccharide synthesis].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20020501

Stem cell toxicity of oxazaphosphorine metabolites in comparison to their antileukemic activity.

Biochemical pharmacology 20020401

Synthesis of the glycosidic precursor of isomeric marmelo lactones, volatile components of the quince fruit, Cydonia oblonga.

Bioscience, biotechnology, and biochemistry 20020401

Modified guanines representing O(6)-alkylation by the cyclophosphamide metabolites acrolein and chloroacetaldehyde: synthesis, stability, and ab initio studies.

Chemical research in toxicology 20020301

Toxicity of chloroacetaldehyde is similar in adult and pediatric kidney tubules.

Pediatric nephrology (Berlin, Germany) 20020201

Respective contribution of neutrophil elastase and matrix metalloproteinase 9 in the degradation of BP180 (type XVII collagen) in human bullous pemphigoid.

The Journal of investigative dermatology 20011101

Simultaneous determination of six adenyl purines in human plasma by high-performance liquid chromatography with fluorescence derivatization.

Journal of chromatography. B, Biomedical sciences and applications 20010825

Human kidney tubules detoxify chloroacetaldehyde, a presumed nephrotoxic metabolite of ifosfamide.

Journal of the American Society of Nephrology : JASN 20010801

Modulation of the cytochrome P450-mediated metabolism of ifosfamide by ketoconazole and rifampin.

Clinical pharmacology and therapeutics 20010801

Comparison of cancer risk estimates for vinyl chloride using animal and human data with a PBPK model.

The Science of the total environment 20010702

Influence of dose and infusion duration on pharmacokinetics of ifosfamide and metabolites.

Drug metabolism and disposition: the biological fate of chemicals 20010701

Gas-phase photocatalytic oxidation of dichlorobutenes.

Environmental science & technology 20010701

Sensitive gas chromatographic determination of the cyclophosphamide metabolite 2-dechloroethylcyclophosphamide in human plasma.

Journal of chromatography. B, Biomedical sciences and applications 20010615

Evaluation of a fluorogenic derivatization method for the reversed-phase HPLC analysis of 2'-beta-fluoro-2',3'-dideoxyadenosine, a new anti-AIDS drug.

Journal of pharmaceutical and biomedical analysis 20010501

2-Chloroacetaldehyde induces epsilondA DNA adducts in DNA of Raji cells as demonstrated by an improved HPLC-fluorimetry method.

Fresenius' journal of analytical chemistry 20010501

[The fluorescent properites of the complexes of 1,3-diphenyl-4-acyl-5-pyrazolones with Eu(III)].

Guang pu xue yu guang pu fen xi = Guang pu 20010401

Selective protection by stably transfected human ALDH3A1 (but not human ALDH1A1) against toxicity of aliphatic aldehydes in V79 cells.

Chemico-biological interactions 20010130

Fluorometric determination of 2'-beta-fluoro-2',3'-dideoxyadenosine 5'-triphosphate, the active metabolite of a new anti-human immunodeficiency virus drug, in human lymphocytes.

Analytical biochemistry 20010101

Technical Advance: a novel technique for the sensitive quantification of acyl CoA esters from plant tissues.

The Plant journal : for cell and molecular biology 20010101

Approach to a multiparametric sensor-chip-based tumor chemosensitivity assay.

Anti-cancer drugs 20010101

Determination of pyrimethamine in animal tissue and egg by liquid chromatography with fluorescence detection.

Journal of AOAC International 20010101

Localization of chloroacetaldehyde-induced DNA damage in human p53 gene by DNA polymerase fingerprint analysis.

IARC scientific publications 19990101

The first structure of an aldehyde dehydrogenase reveals novel interactions between NAD and the Rossmann fold.

Nature structural biology 19970401

Determination of the gene sequence and the three-dimensional structure at 2.4 angstroms resolution of methanol dehydrogenase from Methylophilus W3A1.

Journal of molecular biology 19960614

An intramolecular triplex in the human gamma-globin 5'-flanking region is altered by point mutations associated with hereditary persistence of fetal hemoglobin.

The Journal of biological chemistry 19951013

A meta cleavage pathway for 4-chlorobenzoate, an intermediate in the metabolism of 4-chlorobiphenyl by Pseudomonas cepacia P166.

Applied and environmental microbiology 19950201

Ifosfamide metabolite chloroacetaldehyde causes Fanconi syndrome in the perfused rat kidney.

Toxicology and applied pharmacology 19941101

Chloroacetaldehyde and its contribution to urotoxicity during treatment with cyclophosphamide or ifosfamide. An experimental study/short communication.

Arzneimittel-Forschung 19890601