Home Aminos 5-Nitro-2-((3-phenylpropyl)amino)benzoic acid

5-Nitro-2-((3-phenylpropyl)amino)benzoic acid

CAS No.:
107254-86-4
Catalog Number:
AG003882
Molecular Formula:
C16H16N2O4
Molecular Weight:
300.3092
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
10mg
≥98%
1 week
United States
$118
- +
25mg
≥98%
1 week
United States
$194
- +
50mg
≥98%
1 week
United States
$286
- +
100mg
99%
1 week
United States
$523
- +
Product Description
Catalog Number:
AG003882
Chemical Name:
5-Nitro-2-((3-phenylpropyl)amino)benzoic acid
CAS Number:
107254-86-4
Molecular Formula:
C16H16N2O4
Molecular Weight:
300.3092
MDL Number:
MFCD00153851
IUPAC Name:
5-nitro-2-(3-phenylpropylamino)benzoic acid
InChI:
InChI=1S/C16H16N2O4/c19-16(20)14-11-13(18(21)22)8-9-15(14)17-10-4-7-12-5-2-1-3-6-12/h1-3,5-6,8-9,11,17H,4,7,10H2,(H,19,20)
InChI Key:
WBSMIPAMAXNXFS-UHFFFAOYSA-N
SMILES:
OC(=O)c1cc(ccc1NCCCc1ccccc1)[N+](=O)[O-]
UNII:
3A35O9G3YZ
Properties
Complexity:
377  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
300.111g/mol
Formal Charge:
0
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
300.314g/mol
Monoisotopic Mass:
300.111g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
95.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4.1  
Literature
Title Journal
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Oxidative stress and alterations in actin cytoskeleton trigger glutathione efflux in Saccharomyces cerevisiae. Biochimica et biophysica acta 20101201
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NPPB structure-specifically activates TRPA1 channels. Biochemical pharmacology 20100701
Proteinase-activated receptors-1 and 2 induce electrogenic Cl- secretion in the mouse cecum by distinct mechanisms. American journal of physiology. Gastrointestinal and liver physiology 20100701
A possible mechanism and sequence of events that lead to the Al3+-induced [Ca2+]cyt transients and inhibition of root growth. Plant signaling & behavior 20100701
Activation of volume-sensitive Cl(-) channel is involved in carboplatin-induced apoptosis in human lung adenocarcinoma cells. Cancer biology & therapy 20100601
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Anion conductance of the human red cell is carried by a maxi-anion channel. Blood cells, molecules & diseases 20100415
Volume-sensitive outwardly rectifying chloride channel in white adipocytes from normal and diabetic mice. American journal of physiology. Cell physiology 20100401
In vitro activation of GAT1 transporters expressed in spinal cord gliosomes stimulates glutamate release that is abnormally elevated in the SOD1/G93A(+) mouse model of amyotrophic lateral sclerosis. Journal of neurochemistry 20100401
MRP transporters as membrane machinery in the bradykinin-inducible export of ATP. Naunyn-Schmiedeberg's archives of pharmacology 20100401
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Gamma-vinyl GABA increases nonvesicular release of GABA and glutamate in the nucleus accumbens in rats via action on anion channels and GABA transporters. Psychopharmacology 20100301
GTPase-Rac enhances depolarization-induced superoxide production by the macula densa during tubuloglomerular feedback. American journal of physiology. Regulatory, integrative and comparative physiology 20100201
Characterization of ion transport in the isolated epipodite of the lobster Homarus americanus. The Journal of experimental biology 20100201
Cell volume decrease as a link between azaspiracid-induced cytotoxicity and c-Jun-N-terminal kinase activation in cultured neurons. Toxicological sciences : an official journal of the Society of Toxicology 20100101
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5-Nitro-2-(3-phenylpropylamino)benzoic acid (NPPB) stimulates cellular ATP release through exocytosis of ATP-enriched vesicles. The Journal of biological chemistry 20091204
The actions of chloride channel blockers, barbiturates and a benzodiazepine on Caenorhabditis elegans glutamate- and ivermectin-gated chloride channel subunits expressed in Xenopus oocytes. Invertebrate neuroscience : IN 20091201
Microglia processes block the spread of damage in the brain and require functional chloride channels. Glia 20091115
Characteristics of Cl- uptake in rat alveolar type I cells. American journal of physiology. Lung cellular and molecular physiology 20091101
Protection by taurine of rat brain cortical slices against oxygen glucose deprivation- and reoxygenation-induced damage. European journal of pharmacology 20091025
Apoptotic inducers activate the release of D-aspartate through a hypotonic stimulus-triggered mechanism in PC12 cells. Archives of biochemistry and biophysics 20091015
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Chloride channels involve in hydrogen peroxide-induced apoptosis of PC12 cells. Biochemical and biophysical research communications 20091002
Plasmodium berghei-infection induces volume-regulated anion channel-like activity in human hepatoma cells. Cellular microbiology 20091001
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology 20091001
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Regulation of ovarian cancer cell adhesion and invasion by chloride channels. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20090501
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Caffeine-inducible ATP release is mediated by Ca2+-signal transducing system from the endoplasmic reticulum to mitochondria. Naunyn-Schmiedeberg's archives of pharmacology 20080701
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Connexin 43 hemichannels are permeable to ATP. The Journal of neuroscience : the official journal of the Society for Neuroscience 20080430
Rutaecarpine induces chloride secretion across rat isolated distal colon. The Journal of pharmacology and experimental therapeutics 20080401
Aortas isolated from sinoaortic-denervated rats exhibit rhythmic contractions that are regulated by pharmacologically distinct calcium sources. Basic & clinical pharmacology & toxicology 20080401
Apparent intermediate K conductance channel hyposmotic activation in human lens epithelial cells. American journal of physiology. Cell physiology 20080301
Potassium-chloride promiscuous channels in mitochondrial membranes. General physiology and biophysics 20080301
Electrophysiological characterization of the node in Chara corallina: functional differentiation for wounding response. Plant & cell physiology 20080201
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The product of the gene GEF1 of Saccharomyces cerevisiae transports Cl- across the plasma membrane. FEMS yeast research 20071201
Regulatory volume decrease after swelling induced by urea in fibroblasts: prominent role of organic osmolytes. Molecular and cellular biochemistry 20071201
Regulation of paracellular ion conductances by NaCl gradients in renal epithelial cells. Biochemical and biophysical research communications 20071123
Translocator protein (18 kDa) ligand PK 11195 induces transient mitochondrial Ca2+ release leading to transepithelial Cl- secretion in HT-29 human colon cancer cells. Biology of the cell 20071101
HCO(-3)-dependent pHi recovery and overacidification induced by NH+4 pulse in rat lung alveolar type II cells: HCO(-3)-dependent NH3 excretion from lungs? Pflugers Archiv : European journal of physiology 20071101
Inhibition of ERK and JNK decreases both osmosensitive taurine release and cell proliferation in glioma cells. Neurochemical research 20071101
Inhibitory effect of DIDS, NPPB, and phloretin on intracellular chloride channels. Pflugers Archiv : European journal of physiology 20071101
Functional ion channels in mouse bone marrow mesenchymal stem cells. American journal of physiology. Cell physiology 20071101
[Cl-]i modulation of Ca2+-regulated exocytosis in ACh-stimulated antral mucous cells of guinea pig. American journal of physiology. Gastrointestinal and liver physiology 20071001
pH stat studies on bicarbonate secretion in the isolated mouse ileum. Biomedical research (Tokyo, Japan) 20071001
SLC26A7 can function as a chloride-loading mechanism in parietal cells. Pflugers Archiv : European journal of physiology 20070901
CFTR-dependent Cl- secretion in Xenopus laevis lung epithelium. Respiratory physiology & neurobiology 20070815
An outwardly rectifying anionic background current in atrial myocytes from the human heart. Biochemical and biophysical research communications 20070803
Acute inflammation alters bicarbonate transport in mouse ileum. The Journal of physiology 20070615
Basolateral Cl channels in primary airway epithelial cultures. American journal of physiology. Lung cellular and molecular physiology 20070601
Tin protoporphyrin induces intestinal chloride secretion by inducing light oxidation processes. American journal of physiology. Cell physiology 20070501
Physiological significance of hypotonicity-induced regulatory volume decrease: reduction in intracellular Cl- concentration acting as an intracellular signaling. American journal of physiology. Renal physiology 20070501
Effects of monocarboxylic acid-derived Cl- channel blockers on depolarization-activated potassium currents in rat ventricular myocytes. Experimental physiology 20070501
Differential dependence of regulatory volume decrease behavior in rabbit corneal epithelial cells on MAPK superfamily activation. Experimental eye research 20070501
Inhibition of P-type ATPases by [(dihydroindenyl)oxy]acetic acid (DIOA), a K+ -Cl- cotransporter inhibitor. European journal of pharmacology 20070410
Epithelial ion transport of human nasal polyp and paranasal sinus mucosa. American journal of respiratory cell and molecular biology 20070401
Electrophysiological studies of malaria parasite-infected erythrocytes: current status. International journal for parasitology 20070401
Roles of volume-activated Cl- currents and regulatory volume decrease in the cell cycle and proliferation in nasopharyngeal carcinoma cells. Cell proliferation 20070401
Bioelectric properties of chloride channels in human, pig, ferret, and mouse airway epithelia. American journal of respiratory cell and molecular biology 20070301
Haemolysin produced by Vibrio mimicus activates two Cl- secretory pathways in cultured intestinal-like Caco-2 cells. Cellular microbiology 20070301
Mechanisms of secretion-associated shrinkage and volume recovery in cultured rabbit parietal cells. American journal of physiology. Gastrointestinal and liver physiology 20070301
Vitamin C transport and SVCT1 transporter expression in chick renal proximal tubule cells in culture. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20070301
Roles of volume-sensitive chloride channel in excitotoxic neuronal injury. The Journal of neuroscience : the official journal of the Society for Neuroscience 20070207
Extracellular pH alkalinization by Cl-/HCO3- exchanger is crucial for TASK2 activation by hypotonic shock in proximal cell lines from mouse kidney. American journal of physiology. Renal physiology 20070201
Is the glucose-induced phosphate flush in pancreatic islets attributable to gating of volume-sensitive anion channels? Endocrine 20070201
Caspase-dependent and -independent induction of phosphatidylserine externalization during apoptosis in human renal carcinoma Cak(1)-1 and A-498 cells. Toxicology 20070105
Characterisation of chloride currents across the proximal colon in CftrTgH(neoim)1Hgu congenic mice. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20070101
Characterization of a novel voltage-dependent outwardly rectifying anion current in Caenorhabditis elegans oocytes. American journal of physiology. Cell physiology 20070101
Evidence for cystic fibrosis transmembrane conductance regulator chloride current in swine ventricular myocytes. Journal of molecular and cellular cardiology 20070101
Blockage of volume-activated chloride channels inhibits migration of nasopharyngeal carcinoma cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101
PI3 kinase dependent stimulation of gastric acid secretion by dexamethasone. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101
Ion channel diversity, channel expression and function in the choroid plexuses. Cerebrospinal fluid research 20070101
Clustering of Helicobacter pylori VacA in lipid rafts, mediated by its receptor, receptor-like protein tyrosine phosphatase beta, is required for intoxication in AZ-521 Cells. Infection and immunity 20061201
Chloride secretion by porcine ciliary epithelium: New insight into species similarities and differences in aqueous humor formation. Investigative ophthalmology & visual science 20061201
Functional characterization of Cl-/HCO3- exchange in villous cells of the mouse ileum. Biomedical research (Tokyo, Japan) 20061201
Stimulus-secretion coupling of hypotonicity-induced insulin release in BRIN-BD11 cells. Endocrine 20061201
The anion channel blocker, 4,4'-dinitrostilbene-2,2'-disulfonic acid prevents neuronal death and excitatory amino acid release during glycolysis inhibition in the hippocampus in vivo. Neuroscience 20061103
[Calcium-dependent chloride channels in plasma membrane of oocytes from toad, Bufo bufo gargarizans]. Sheng li xue bao : [Acta physiologica Sinica] 20061025
VRACs CARVe a path for novel mechanisms of communication in the CNS. Science's STKE : signal transduction knowledge environment 20061017
Effect of chloride on pH microclimate and electrogenic Na+ absorption across the rumen epithelium of goat and sheep. American journal of physiology. Gastrointestinal and liver physiology 20060801
The hydroosmotic response of frog urinary bladder to serosal hypertonicity is dependent on adenylate cyclase for its maintenance and affected by [Cl-]o changes. American journal of physiology. Regulatory, integrative and comparative physiology 20060701
Evidence for a clathrin-mediated recycling of albumin in human term placenta. Biology of reproduction 20060701
Intracellular Cl- fluxes play a novel role in Ca2+ handling in airway smooth muscle. American journal of physiology. Lung cellular and molecular physiology 20060601
Swelling-activated Cl- channels support Cl- secretion by bovine ciliary epithelium. Investigative ophthalmology & visual science 20060601
Mechanism of iodide transport in the rabbit cortical collecting duct. Clinical and experimental nephrology 20060601
Anion channels, including ClC-3, are required for normal neutrophil oxidative function, phagocytosis, and transendothelial migration. The Journal of biological chemistry 20060505
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Regulation of taurine transport in rat hippocampal neurons by hypo-osmotic swelling. Journal of neurochemistry 20060301
Roles for KCC transporters in the maintenance of lens transparency. Investigative ophthalmology & visual science 20060201
Bicarbonate-rich choleresis induced by secretin in normal rat is taurocholate-dependent and involves AE2 anion exchanger. Hepatology (Baltimore, Md.) 20060201
Development and validation of HTS flux assay for endogenously expressed chloride channels in a CHO-K1 cell line. Assay and drug development technologies 20060201
Chloride-dependent bicarbonate secretion in the mouse large intestine. Biomedical research (Tokyo, Japan) 20060201
Ionic mechanism of forskolin-induced liquid secretion by porcine bronchi. American journal of physiology. Lung cellular and molecular physiology 20060101
S-CMC-Lys-dependent stimulation of electrogenic glutathione secretion by human respiratory epithelium. Journal of molecular medicine (Berlin, Germany) 20060101
Changes in ion transport in inflammatory disease. Journal of inflammation (London, England) 20060101
Functional characterization of wild-type and a mutated form of SLC26A4 identified in a patient with Pendred syndrome. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20060101
Elucidation of the mechanisms underlying hypo-osmotically induced turgor pressure regulation in the marine alga Valonia utricularis. The Journal of membrane biology 20060101
Swelling-activated K+ efflux and regulatory volume decrease efficiency in human bronchial epithelial cells. The Journal of membrane biology 20060101
Chloride channels in physiological volume regulation of human spermatozoa. Biology of reproduction 20051101
Effect of Cl- channel blockers on aconitine-induced arrhythmias in rat heart. Experimental physiology 20051101
Volume-activated chloride currents in interstitial cells of Cajal. American journal of physiology. Gastrointestinal and liver physiology 20051101
Identification and functional characterization of a voltage-gated chloride channel and its novel splice variant in taste bud cells. The Journal of biological chemistry 20051028
Quercetin and NPPB-induced diminution of aldosterone action on Na+ absorption and ENaC expression in renal epithelium. Biochemical and biophysical research communications 20051021
Melatonin potentiates flavone-induced apoptosis in human colon cancer cells by increasing the level of glycolytic end products. International journal of cancer 20050820
Hemin induces active chloride secretion in Caco-2 cells. American journal of physiology. Gastrointestinal and liver physiology 20050801
[Regulatory volume decrease and its mechanism in nasopharyngeal epithelial cells]. Shi yan sheng wu xue bao 20050801
[Inhibitory effects of chloride channel blockers NPPB on proliferation of human glomerular mesangial cells]. Yao xue xue bao = Acta pharmaceutica Sinica 20050801
Synergic action of insulin and genistein on Na+/K+/2Cl- cotransporter in renal epithelium. Biochemical and biophysical research communications 20050715
Intermediate-conductance Ca2+-activated K+ channel is expressed in C2C12 myoblasts and is downregulated during myogenesis. American journal of physiology. Cell physiology 20050701
Role of chloride channels in bradykinin-induced guinea pig airway vagal C-fibre activation. The Journal of physiology 20050701
[Background chloride currents in fetal human nasopharyngeal epithelial cells]. Sheng li xue bao : [Acta physiologica Sinica] 20050625
Activating cystic fibrosis transmembrane conductance regulator channels with pore blocker analogs. The Journal of biological chemistry 20050624
Relative contribution of chloride channels and transporters to regulatory volume decrease in human glioma cells. American journal of physiology. Cell physiology 20050601
Chloride channel activity in human lung fibroblasts and myofibroblasts. American journal of physiology. Lung cellular and molecular physiology 20050601
Interdependency of beta-adrenergic receptors and CFTR in regulation of alveolar active Na+ transport. Circulation research 20050513
Activation of gamma-aminobutyric acid GAT-1 transporters on glutamatergic terminals of mouse spinal cord mediates glutamate release through anion channels and by transporter reversal. Journal of neuroscience research 20050501
The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites. Molecular cancer therapeutics 20050501
Involvement of regulatory volume decrease in the migration of nasopharyngeal carcinoma cells. Cell research 20050501
Tonic release of glutamate by a DIDS-sensitive mechanism in rat hippocampal slices. The Journal of physiology 20050415
Removal of the nitro and phenyl groups from NPPB decreases its inhibitory effect on cytoplasmic streaming in the alga Nitella hookeri. Biochemistry and cell biology = Biochimie et biologie cellulaire 20050401
Blockade of chloride conductance antagonizes PMA-induced ramification in the murine microglial cell line, BV-2. Brain research 20050328
Location of a common inhibitor binding site in the cytoplasmic vestibule of the cystic fibrosis transmembrane conductance regulator chloride channel pore. The Journal of biological chemistry 20050311
Mechanism of augmented duodenal HCO(3)(-) secretion after elevation of luminal CO(2). American journal of physiology. Gastrointestinal and liver physiology 20050301
Mechanisms of chloride influx during KCl-induced swelling in the chicken retina. Pflugers Archiv : European journal of physiology 20050301
Inhibition of swelling-activated Cl- currents by functional anti-ClC-3 antibody in native bovine non-pigmented ciliary epithelial cells. Investigative ophthalmology & visual science 20050301
alpha-Lipoic acid induces apoptosis in human colon cancer cells by increasing mitochondrial respiration with a concomitant O2-*-generation. Apoptosis : an international journal on programmed cell death 20050301
Hydrogen peroxide potentiates volume-sensitive excitatory amino acid release via a mechanism involving Ca2+/calmodulin-dependent protein kinase II. The Journal of biological chemistry 20050204
Hyperosmolarity increases K+-induced vasodilations in rat skeletal muscle arterioles. Medicine and science in sports and exercise 20050201
HCO(3)(-)-independent rescue from apoptosis by stilbene derivatives in rat cardiomyocytes. FEBS letters 20050117
Chloride channels in the small intestinal cell line IEC-18. Journal of cellular physiology 20050101
Vasopressin-stimulated CFTR Cl- currents are increased in the renal collecting duct cells of a mouse model of Liddle's syndrome. The Journal of physiology 20050101
Excitotoxic death induced by released glutamate in depolarized primary cultures of mouse cerebellar granule cells is dependent on GABAA receptors and niflumic acid-sensitive chloride channels. The European journal of neuroscience 20050101
PI3K and PKC contribute to membrane depolarization mediated by alpha2-adrenoceptors in the canine isolated mesenteric vein. BMC physiology 20050101
Monitoring Cl- movement in single cells exposed to hypotonic solution. The Journal of membrane biology 20050101
Chloride channel inhibition prevents ROS-dependent apoptosis induced by ischemia-reperfusion in mouse cardiomyocytes. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20050101
Study of the effect of ion channel modulators on photosynthetic oxygen evolution. Journal of chemical information and modeling 20050101
Role of Cl- in cerebral vascular tone and expression of Na+-K+-2Cl- co-transporter after neonatal hypoxia-ischemia. Canadian journal of physiology and pharmacology 20050101
Activation of chloride current and decrease of cell volume by ATP in nasopharyngeal carcinoma cells. Sheng li xue bao : [Acta physiologica Sinica] 20041225
Depolarisation of the plasma membrane in the arsenic trioxide (As2O3)-and anti-CD95-induced apoptosis in myeloid cells. FEBS letters 20041203
Electrophysiological characterization of volume-activated chloride currents in mouse cholangiocyte cell line. American journal of physiology. Gastrointestinal and liver physiology 20041201
Cl- channels are expressed in human normal monocytes: a functional role in migration, adhesion and volume change. Clinical and experimental immunology 20041201
Involvement of cytosolic Cl- in osmoregulation of alpha-ENaC gene expression. American journal of physiology. Renal physiology 20041101
Volume regulation of mature and immature spermatozoa in a primate model, and possible ion channels involved. Human reproduction (Oxford, England) 20041101
Role of volume-stimulated osmolyte and anion channels in volume regulation by mammalian sperm. Molecular human reproduction 20041101
Enhanced release of synaptic glutamate underlies the potentiation of oxygen-glucose deprivation-induced neuronal injury after induction of NOS-2. Experimental neurology 20041101
The relationship between cell proliferation, Cl- secretion, and renal cyst growth: a study using CFTR inhibitors. Kidney international 20041101
Investigation of the mechanism of nicotine-induced relaxation on the sheep sphincter of Oddi. Canadian journal of physiology and pharmacology 20041101
Chloride efflux is involved in ET-1 and 5-HT-induced contraction in rabbit basilar artery. Journal of cardiovascular pharmacology 20041101
cAMP-activated maxi-Cl(-) channels in native bovine pigmented ciliary epithelial cells. American journal of physiology. Cell physiology 20041001
cAMP inhibits transepithelial chloride secretion across bovine ciliary body/epithelium. Investigative ophthalmology & visual science 20041001
Volume-sensitive chloride channels (ICl,vol) mediate doxorubicin-induced apoptosis through apoptotic volume decrease in cardiomyocytes. Fundamental & clinical pharmacology 20041001
Time-dependent interactions of glibenclamide with CFTR: kinetically complex block of macroscopic currents. The Journal of membrane biology 20041001
Volume-activated Cl- current in migrated nasopharyngeal carcinoma cells. Sheng li xue bao : [Acta physiologica Sinica] 20040825
NPPB block of the intermediate-conductance Ca2+-activated K+ channel. European journal of pharmacology 20040816
The glutathione reductase inhibitor carmustine induces an influx of Ca2+ in PC12 cells. European journal of pharmacology 20040816
Defining pathways of loss and secretion of chemical messengers from astrocytes. Glia 20040815
Discovery of glycine hydrazide pore-occluding CFTR inhibitors: mechanism, structure-activity analysis, and in vivo efficacy. The Journal of general physiology 20040801
Uridine 5'-triphosphate stimulates alveolar fluid clearance in the isolated rat lungs. Journal of pharmacological sciences 20040801
Prostaglandin E2 activates outwardly rectifying Cl(-) channels via a cAMP-dependent pathway and reduces cell motility in rat osteoclasts. American journal of physiology. Cell physiology 20040701
Effects of a new cystic fibrosis transmembrane conductance regulator inhibitor on Cl- conductance in human sweat ducts. Experimental physiology 20040701
Volume changes and whole cell membrane currents activated during gradual osmolarity decrease in C6 glioma cells: contribution of two types of K+ channels. American journal of physiology. Cell physiology 20040601
Low-dose PGE2 mimics the duodenal secretory response to luminal acid in mice. American journal of physiology. Gastrointestinal and liver physiology 20040601
Effects of chloride and potassium channel blockers on apoptotic cell shrinkage and apoptosis in cortical neurons. Pflugers Archiv : European journal of physiology 20040601
Volume-sensitive chloride channels do not mediate activation-induced chloride efflux in human neutrophils. Journal of immunology (Baltimore, Md. : 1950) 20040601
Glutamate-induced elevations in intracellular chloride concentration in hippocampal cell cultures derived from EYFP-expressing mice. The European journal of neuroscience 20040601
Impaired regulatory volume decrease in freshly isolated cholangiocytes from cystic fibrosis mice: implications for cystic fibrosis transmembrane conductance regulator effect on potassium conductance. The Journal of biological chemistry 20040409
Suppression of cell proliferation with induction of p21 by Cl(-) channel blockers in human leukemic cells. European journal of pharmacology 20040319
Glycosylphosphatidylinositol-anchored proteins and actin cytoskeleton modulate chloride transport by channels formed by the Helicobacter pylori vacuolating cytotoxin VacA in HeLa cells. The Journal of biological chemistry 20040305
Hypotonic cell swelling stimulates permeability to cAMP in a rat colonic cell line. Pflugers Archiv : European journal of physiology 20040301
Effect of propofol on hypotonic swelling-induced membrane depolarization in human coronary artery smooth muscle cells. Anesthesiology 20040301
Vasopressin-induced taurine efflux from rat pituicytes: a potential negative feedback for hormone secretion. The Journal of physiology 20040201
Leukotrienes-mediated effects of water extracts from Sargassum horneri, a marine brown alga, on Cl- absorption in isolated rat colon. The Japanese journal of physiology 20040201
NHE3 inhibition activates duodenal bicarbonate secretion in the rat. American journal of physiology. Gastrointestinal and liver physiology 20040101
Hyperosmolar solution effects in guinea pig airways. II. Epithelial bioelectric responses to relative changes in osmolarity. The Journal of pharmacology and experimental therapeutics 20040101
Chloride-dependent calcium transients induced by angiotensin II in vascular smooth muscle cells. American journal of physiology. Cell physiology 20040101
Investigations of pharmacologic properties of the renal CLC-K1 chloride channel co-expressed with barttin by the use of 2-(p-Chlorophenoxy)propionic acid derivatives and other structurally unrelated chloride channels blockers. Journal of the American Society of Nephrology : JASN 20040101
Cl- channel blockers NPPB and niflumic acid blunt Ca(2+)-induced erythrocyte 'apoptosis'. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20040101
The Cl(-) channel blocker niflumic acid releases Ca(2+) from an intracellular store in rat pulmonary artery smooth muscle cells. British journal of pharmacology 20031201
Role of Cl- currents in rat aortic smooth muscle activation by prostaglandin F2 alpha. European journal of pharmacology 20031128
Independence of apical Cl-/HCO3- exchange and anion conductance in duodenal HCO3- secretion. American journal of physiology. Gastrointestinal and liver physiology 20031101
Fundamental role of ClC-3 in volume-sensitive Cl- channel function and cell volume regulation in AGS cells. American journal of physiology. Gastrointestinal and liver physiology 20031101
CLCA protein and chloride transport in canine retinal pigment epithelium. American journal of physiology. Cell physiology 20031101
Pharmacological sensitivity of ATP release triggered by photoliberation of inositol-1,4,5-trisphosphate and zero extracellular calcium in brain endothelial cells. Journal of cellular physiology 20031101
Prostaglandin E2 stimulates sodium reabsorption in MDCK C7 cells, a renal collecting duct principal cell model. Prostaglandins, leukotrienes, and essential fatty acids 20031101
Transport of Cl- across the plasma membrane during pollen grain germination in tobacco. Biochemistry. Biokhimiia 20031101
Characterization of Cl-HCO3 exchange in basolateral membrane of rat distal colon. American journal of physiology. Cell physiology 20031001
Activation of muscarinic cholinergic receptors enhances the volume-sensitive efflux of myo-inositol from SH-SY5Y neuroblastoma cells. Journal of neurochemistry 20031001
Inhibitors of swelling-activated chloride channels increase infarct size and apoptosis in rabbit myocardium. Fundamental & clinical pharmacology 20031001
Role of Ca2+-activated Cl- channels in the mechanism of apoptosis induced by cyclosporin A in a human hepatoma cell line. Biochemical and biophysical research communications 20030919
Propofol inhibits volume-sensitive chloride channels in human coronary artery smooth muscle cells. Anesthesia and analgesia 20030901
Expression of voltage-gated chloride channels in human glioma cells. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030702
Aluminum rapidly depolymerizes cortical microtubules and depolarizes the plasma membrane: evidence that these responses are mediated by a glutamate receptor. Plant & cell physiology 20030701
Chloride influx aggravates Ca2+-dependent AMPA receptor-mediated motoneuron death. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030615
Contribution of chloride channels to volume regulation of cortical astrocytes. American journal of physiology. Cell physiology 20030601
Chlorotoxin-sensitive Ca2+-activated Cl- channel in type R2 reactive astrocytes from adult rat brain. Glia 20030601
Swelling-activated chloride and potassium conductance in primary cultures of mouse proximal tubules. Implication of KCNE1 protein. The Journal of membrane biology 20030601
PTH stimulates a Cl(-)-dependent and EIPA-sensitive current in chick proximal tubule cells in culture. American journal of physiology. Renal physiology 20030501
HCO(3)(-)-dependent soluble adenylyl cyclase activates cystic fibrosis transmembrane conductance regulator in corneal endothelium. American journal of physiology. Cell physiology 20030501
Ca2+-activated Cl- channel currents in rat ventral prostate epithelial cells. The Prostate 20030501
Secretion of acid and base equivalents by intact distal airways. American journal of physiology. Lung cellular and molecular physiology 20030501
[Effect of anions and anion channel blockers on vascular tone in rat aorta]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20030501
Pharmacological investigation of the role of ion channels in salivary secretion. Pflugers Archiv : European journal of physiology 20030401
Cl- channel blockers inhibit transition of quiescent (G0) fibroblasts into the cell cycle. Journal of cellular physiology 20030301
Effects of ion transport and channel-blocking drugs on aqueous humor formation in isolated bovine eye. Investigative ophthalmology & visual science 20030301
Amino acid-permeable anion channels in early mouse embryos and their possible effects on cleavage. Biology of reproduction 20030301
A novel chloride conductance activated by extracellular ATP in mouse parotid acinar cells. The Journal of physiology 20030215
Enhancement of aquaporin-3 by vasoactive intestinal polypeptide in a human colonic epithelial cell line. Journal of gastroenterology and hepatology 20030201
Hypotonic-induced transport pathways in Xenopus laevis erythrocytes: taurine fluxes. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20030201
Preliminary pharmacological characterisation of an interleukin-13-enhanced calcium-activated chloride conductance in the human airway epithelium. Naunyn-Schmiedeberg's archives of pharmacology 20030201
A chloride channel blocker reduces acetylcholine uptake into synaptic vesicles at the frog neuromuscular junction. Brain research 20030131
The synthesis of NPPB and NPBB by reductive amination and the effects of these compounds on K+ channels of the alga Nitella hookeri. Bioorganic & medicinal chemistry letters 20030120
Basolateral Ca2+-dependent K+-channels play a key role in Cl- secretion induced by taurodeoxycholate from colon mucosa. Biology of the cell 20030101
Taurine enhances volume regulation in hippocampal slices swollen osmotically. Neuroscience 20030101
Impaired activity of volume-sensitive anion channel during lactacidosis-induced swelling in neuronally differentiated NG108-15 cells. Brain research 20021206
Terbutaline-induced triphasic changes in volume of rat alveolar type II cells: the role of cAMP. The Japanese journal of physiology 20021201
Effects of 5-nitro-2-(3-phenylpropylamino) benzoic acid, anthracene-9-carboxylate, and zaprinast on endothelin-1-induced contractions of pregnant rat myometrium. European journal of obstetrics, gynecology, and reproductive biology 20021115
Control of Cl- transport in the operculum epithelium of Fundulus heteroclitus: long- and short-term salinity adaptation. Biochimica et biophysica acta 20021113
Effects of bile acids on dog pancreatic duct epithelial cell secretion and monolayer resistance. American journal of physiology. Gastrointestinal and liver physiology 20021101
Anion channels influence ECC by modulating L-type Ca(2+) channel in ventricular myocytes. Journal of applied physiology (Bethesda, Md. : 1985) 20021101
Factors affecting ammonium uptake by C11 clone of MDCK cells. Pflugers Archiv : European journal of physiology 20021101
Inhibition of vacuolation toxin activity of Helicobacter pylori by iodine, nitrite and potentiation by sodium chloride, sterigmatocystin and fluoride. Toxicology in vitro : an international journal published in association with BIBRA 20021001
Regulatory volume decrease is actively modulated during the cell cycle. Journal of cellular physiology 20021001
Cell cycle-dependent expression of volume-activated chloride currents in nasopharyngeal carcinoma cells. American journal of physiology. Cell physiology 20021001
Receptor-mediated activation of a Cl(-) current by LPA and S1P in cultured corneal keratocytes. Investigative ophthalmology & visual science 20021001
Tyrosine kinases and amino acid efflux under hyposmotic and ischaemic conditions in the chicken retina. Pflugers Archiv : European journal of physiology 20021001
Study of a glucose-activated anion-selective channel in rat pancreatic beta-cells. Pflugers Archiv : European journal of physiology 20021001
Plasmalemmal voltage-activated K(+) currents in protoplasts from tobacco BY-2 cells: possible regulation by actin microfilaments? Protoplasma 20021001
NSAIDs counteract H. pylori VacA toxin-induced cell vacuolation in MKN 28 gastric mucosal cells. American journal of physiology. Gastrointestinal and liver physiology 20020901
Pituitary adenylate cyclase-activating polypeptide induces a sustained increase in intracellular free Ca(2+) concentration and catechol amine release by activating Ca(2+) influx via receptor-stimulated Ca(2+) entry, independent of store-operated Ca(2+) channels, and voltage-dependent Ca(2+) channels in bovine adrenal medullary chromaffin cells. The Journal of pharmacology and experimental therapeutics 20020901
Effect of anion transport blockers on CFTR in the human sweat duct. The Journal of membrane biology 20020901
Oscillatory chloride efflux at the pollen tube apex has a role in growth and cell volume regulation and is targeted by inositol 3,4,5,6-tetrakisphosphate. The Plant cell 20020901
The DC electrical-field-induced Ca(2+) response and growth stimulation of multicellular tumor spheroids are mediated by ATP release and purinergic receptor stimulation. Journal of cell science 20020815
Liquid secretion inhibitors reduce mucociliary transport in glandular airways. American journal of physiology. Lung cellular and molecular physiology 20020801
Activation of CFTR Cl(-) channel by tyrphostins via a protein tyrosine kinase-independent pathway in forskolin-stimulated renal epithelial A6 cells. Life sciences 20020726
Human trabecular meshwork cell volume regulation. American journal of physiology. Cell physiology 20020701
Calcium and voltage-dependent alterations of cell volume in neuroblastomaxglioma hybrid NG108-15 cells. Pflugers Archiv : European journal of physiology 20020501
Amelioration of myocardial global ischemia/reperfusion injury with volume-regulatory chloride channel inhibitors in vivo. Transplantation 20020427
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. The Journal of biological chemistry 20020419
Expression, localization, and functional evaluation of CFTR in bovine corneal endothelial cells. American journal of physiology. Cell physiology 20020401
Basolateral membrane Cl(-)-, Na(+)-, and K(+)-coupled base transport mechanisms in rat MTALH. American journal of physiology. Renal physiology 20020401
Two functionally distinct organic osmolyte pathways in Plasmodium gallinaceum-infected chicken red blood cells. Biochimica et biophysica acta 20020319
Functional expression of V-ATPases in the plasma membrane of glial cells. Glia 20020315
Analysis of NaCl transport in thin ascending limb of Henle's loop in CLC-K1 null mice. American journal of physiology. Renal physiology 20020301
Volume-activated chloride currents from human fibroblasts: blockade by nimodipine. General physiology and biophysics 20020301
Hydrogen peroxide-induced current in Xenopus oocytes: current characteristics similar to those induced by the removal of extracellular calcium. Biochemical pharmacology 20020215
ACTH-induced Cl(-) current in bovine adrenocortical cells: correlation with cortisol secretion. American journal of physiology. Endocrinology and metabolism 20020201
Swelling-activated taurine and creatine effluxes from rat cortical astrocytes are pharmacologically distinct. The Journal of membrane biology 20020115
Transepithelial impedance analysis of chloride secretion. Methods in molecular medicine 20020101
Cellular bicarbonate protects rat duodenal mucosa from acid-induced injury. The Journal of clinical investigation 20011215
Nystatin and valinomycin induce tubuloglomerular feedback. American journal of physiology. Renal physiology 20011201
Helicobacter pylori cytotoxin VacA increases alkaline secretion in gastric epithelial cells. American journal of physiology. Gastrointestinal and liver physiology 20011201
Blue-light-dependent osmoregulation in protoplasts of Phaseolus vulgaris Pulvini. Plant & cell physiology 20011201
Induction of H(2)O(2) synthesis by beta-glucan elicitors in soybean is independent of cytosolic calcium transients. FEBS letters 20011116
Examining basal chloride transport using the nasal potential difference response in a murine model. American journal of physiology. Lung cellular and molecular physiology 20011101
Role of Cl- current in endothelin-1-induced contraction in rabbit basilar artery. American journal of physiology. Heart and circulatory physiology 20011101
Multidrug resistance-like genes of Arabidopsis required for auxin transport and auxin-mediated development. The Plant cell 20011101
Auxin- and abscisic acid-dependent osmoregulation in protoplasts of Phaseolus vulgaris pulvini. Plant & cell physiology 20011101
Novel effects of minocycline on Ca(2+)-dependent Cl(-) secretion in human airway epithelial Calu-3 cells. Toxicology and applied pharmacology 20011015
Selective inhibition of Cl(-) conductance in toad skin by blockers of Cl(-) channels and transporters. American journal of physiology. Cell physiology 20011001
Volume-activated chloride currents contribute to the resting conductance and invasive migration of human glioma cells. The Journal of neuroscience : the official journal of the Society for Neuroscience 20011001
Chloride channel inhibition does block the protection of ischemic preconditioning in myocardium. Journal of molecular and cellular cardiology 20011001
Phenanthrolines--a new class of CFTR chloride channel openers. British journal of pharmacology 20011001
Osmoregulation of vasopressin secretion via activation of neurohypophysial nerve terminals glycine receptors by glial taurine. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010915
The Helicobacter pylori VacA toxin is a urea permease that promotes urea diffusion across epithelia. The Journal of clinical investigation 20010915
CFTR modulates programmed cell death by decreasing intracellular pH in Chinese hamster lung fibroblasts. American journal of physiology. Cell physiology 20010901
CFTR disruption impairs cAMP-dependent Cl(-) secretion in primary cultures of mouse cortical collecting ducts. American journal of physiology. Renal physiology 20010901
Mechanism of substance P-induced liquid secretion across bronchial epithelium. American journal of physiology. Lung cellular and molecular physiology 20010901
Multiple transport functions of a red blood cell anion exchanger, tAE1: its role in cell volume regulation. The Journal of physiology 20010901
[(Dihydroindenyl)oxy]alkonic acid inhibits the cystic fibrosis transmembrane conductance regulator. European journal of pharmacology 20010831
Liquid transport properties of porcine tracheal epithelium. Journal of applied physiology (Bethesda, Md. : 1985) 20010801
'Avian-type' renal medullary tubule organization causes immaturity of urine-concentrating ability in neonates. Kidney international 20010801
Bile duct epithelia regulate biliary bicarbonate excretion in normal rat liver. Gastroenterology 20010801
Evidence for two mechanisms of amino acid osmolyte release from hippocampal slices. Pflugers Archiv : European journal of physiology 20010801
Forskolin activation of apical Cl- channel and Na+/K+/2Cl- cotransporter via a PTK-dependent pathway in renal epithelium. Biochemical and biophysical research communications 20010727
Release of ATP by a human retinal pigment epithelial cell line: potential for autocrine stimulation through subretinal space. The Journal of physiology 20010701
Intestinal bicarbonate secretion in cystic fibrosis mice. JOP : Journal of the pancreas 20010701
Duodenal intracellular bicarbonate and the 'CF paradox'. JOP : Journal of the pancreas 20010701
Properties of synchronous and asynchronous release during pulse train depression in cultured hippocampal neurons. Journal of neurophysiology 20010601
Blocking swelling-activated chloride current inhibits mouse liver cell proliferation. The Journal of physiology 20010501
Ionic balance in the freshwater-adapted Chinese crab, Eriocheir sinensis. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20010501
pH-sensitive inwardly rectifying chloride current in cultured rat cortical astrocytes. Glia 20010401
ATP stimulates calcium-dependent glutamate release from cultured astrocytes. Journal of neurochemistry 20010401
Maxi K+ channels co-localised with CFTR in the apical membrane of an exocrine gland acinus: possible involvement in secretion. Pflugers Archiv : European journal of physiology 20010401
Expression of chloride channel, ClC-5, and its role in receptor-mediated endocytosis of albumin in OK cells. Biochemical and biophysical research communications 20010323
Cl- channel inhibitors of the arylaminobenzoate type act as photosystem II herbicides: a functional and structural study. Biochemistry 20010320
NH(2)-terminal modification of a channel-forming peptide increases capacity for epithelial anion secretion. American journal of physiology. Cell physiology 20010301
Characterization of apical membrane Cl-dependent Na/H exchange in crypt cells of rat distal colon. American journal of physiology. Gastrointestinal and liver physiology 20010301
Inhibition of caspase 3 abrogates lipopolysaccharide-induced nitric oxide production by preventing activation of NF-kappaB and c-Jun NH2-terminal kinase/stress-activated protein kinase in RAW 264.7 murine macrophage cells. Infection and immunity 20010301
Swelling-activated taurine and K+ transport in human cervical cancer cells: association with cell cycle progression. Pflugers Archiv : European journal of physiology 20010301
Vasopressin-stimulated chloride transport in transimmortalized mouse cell lines derived from the distal convoluted tubule and cortical and inner medullary collecting ducts. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010201
Chloride channel function is linked to epithelium-dependent airway relaxation. American journal of physiology. Lung cellular and molecular physiology 20010201
Assessment of CFTR chloride channel openers in intact normal and cystic fibrosis murine epithelia. British journal of pharmacology 20010201
Epidermal growth factor regulates the transition from basal sodium absorption to anion secretion in cultured endometrial epithelial cells. Journal of cellular physiology 20010201
Detection of Cl- flux in the apical microenvironment of cultured foetal distal lung epithelial cells. The Journal of experimental biology 20010201
Extracellular adenosine modulates a volume-sensitive-like chloride conductance in immortalized rabbit DC1 cells. American journal of physiology. Renal physiology 20010101
Adrenergic receptor activated ion transport in human fetal retinal pigment epithelium. Investigative ophthalmology & visual science 20010101
Blockade of chloride channels reveals relaxations of rat small mesenteric arteries to raised potassium. British journal of pharmacology 20010101
Hypertonicity stimulates Cl(-) transport in the intestine of fresh water acclimated eel, Anguilla anguilla. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20010101
Chloride channel blockers 5-nitro-2-(3-phenylpropylamino) benzoic acid and anthracene-9-carboxylic acid inhibit contractions of pregnant rat myometrium in vitro. Journal of the Society for Gynecologic Investigation 20010101
Non-CFTR chloride channels likely contribute to secretion in the murine small intestine. Pflugers Archiv : European journal of physiology 20010101
Activation of potassium and chloride channels by tumor necrosis factor alpha. Role in liver cell death. The Journal of biological chemistry 20000707
Activation of transepithelial ion transport by secretin in human intestinal Caco-2 cells. The Japanese journal of physiology 20000401
Potential role of the JNK/SAPK signal transduction pathway in the induction of iNOS by TNF-alpha. Biochemical and biophysical research communications 19981230
Inhibition of volume-activated chloride currents in endothelial cells by chromones. British journal of pharmacology 19950801
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