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Bumetanide

CAS No.:
28395-03-1
Catalog Number:
AG00383X
Molecular Formula:
C17H20N2O5S
Molecular Weight:
364.4161
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
500mg
98%(HPLC)
In Stock USA
United States
$76
- +
1g
98%
In Stock USA
United States
$112
- +
5g
98%(HPLC)
In Stock USA
United States
$326
- +
10g
98%(HPLC)
In Stock USA
United States
$576
- +
25g
98%
In Stock USA
United States
$1200
- +
Product Description
Catalog Number:
AG00383X
Chemical Name:
Bumetanide
CAS Number:
28395-03-1
Molecular Formula:
C17H20N2O5S
Molecular Weight:
364.4161
MDL Number:
MFCD00078949
IUPAC Name:
3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid
InChI:
InChI=1S/C17H20N2O5S/c1-2-3-9-19-14-10-12(17(20)21)11-15(25(18,22)23)16(14)24-13-7-5-4-6-8-13/h4-8,10-11,19H,2-3,9H2,1H3,(H,20,21)(H2,18,22,23)
InChI Key:
MAEIEVLCKWDQJH-UHFFFAOYSA-N
SMILES:
CCCCNc1cc(cc(c1Oc1ccccc1)S(=O)(=O)N)C(=O)O
EC Number:
249-004-6
UNII:
0Y2S3XUQ5H
NSC Number:
758145
Properties
Complexity:
528  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
364.109g/mol
Formal Charge:
0
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
364.416g/mol
Monoisotopic Mass:
364.109g/mol
Rotatable Bond Count:
8  
Topological Polar Surface Area:
127A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.8  
Literature
Title Journal
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Antioxidants and NOS inhibitors selectively targets manganese-induced cell volume via Na-K-Cl cotransporter-1 in astrocytes. Brain research 20150612
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Enhanced insulin secretion and improved glucose tolerance in mice with homozygous inactivation of the Na(+)K(+)2Cl(-) co-transporter 1. The Journal of endocrinology 20121001
A urine-concentrating defect in 11β-hydroxysteroid dehydrogenase type 2 null mice. American journal of physiology. Renal physiology 20120815
Intracellular Na+, K+ and Cl- activities in Acheta domesticus Malpighian tubules and the response to a diuretic kinin neuropeptide. The Journal of experimental biology 20120815
Upregulation of the Na(+)-K(+)-2Cl(-) cotransporter 1 via histone modification in the aortas of angiotensin II-induced hypertensive rats. Hypertension research : official journal of the Japanese Society of Hypertension 20120801
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ENaC inhibition stimulates Cl- secretion in the mouse cortical collecting duct through an NKCC1-dependent mechanism. American journal of physiology. Renal physiology 20120701
Calcium-sensing receptor inhibits secretagogue-induced electrolyte secretion by intestine via the enteric nervous system. American journal of physiology. Gastrointestinal and liver physiology 20120701
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Altered inhibition in tuberous sclerosis and type IIb cortical dysplasia. Annals of neurology 20120401
Traumatic alterations in GABA signaling disrupt hippocampal network activity in the developing brain. The Journal of neuroscience : the official journal of the Society for Neuroscience 20120321
Intracellular chloride concentration influences the GABAA receptor subunit composition. Nature communications 20120313
Cotransport of water by Na⁺-K⁺-2Cl⁻ cotransporters expressed in Xenopus oocytes: NKCC1 versus NKCC2. The Journal of physiology 20120301
Both NKCC1 and anion exchangers contribute to Cl⁻ accumulation in postnatal forebrain neuronal progenitors. The European journal of neuroscience 20120301
The genetics of loop diuretic effects. The pharmacogenomics journal 20120201
Ischemia-induced stimulation of cerebral microvascular endothelial cell Na-K-Cl cotransport involves p38 and JNK MAP kinases. American journal of physiology. Cell physiology 20120201
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The loop diuretic bumetanide blocks posttraumatic p75NTR upregulation and rescues injured neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 20120201
Propofol facilitated excitatory postsynaptic currents frequency on nucleus tractus solitarii (NTS) neurons. Brain research 20120113
Emodin induces chloride secretion in rat distal colon through activation of mast cells and enteric neurons. British journal of pharmacology 20120101
Evidence for functional atypical nicotinic receptors that activate K+-dependent Cl- secretion in mouse tracheal epithelium. American journal of respiratory cell and molecular biology 20120101
CFTR mediated chloride secretion in the avian renal proximal tubule. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20120101
SPAK/OSR1 regulate NKCC1 and WNK activity: analysis of WNK isoform interactions and activation by T-loop trans-autophosphorylation. The Biochemical journal 20120101
Novel treatment targets for cerebral edema. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20120101
GPR35 is a target of the loop diuretic drugs bumetanide and furosemide. Pharmacology 20120101
Distinct expression/function of potassium and chloride channels contributes to the diverse volume regulation in cortical astrocytes of GFAP/EGFP mice. PloS one 20120101
Defining the cellular environment in the organ of Corti following extensive hair cell loss: a basis for future sensory cell replacement in the Cochlea. PloS one 20120101
Combination of probenecid-sulphadoxine-pyrimethamine for intermittent preventive treatment in pregnancy. Malaria journal 20120101
γ-Aminobutyric acid transporter 2 mediates the hepatic uptake of guanidinoacetate, the creatine biosynthetic precursor, in rats. PloS one 20120101
Modulation of ion transport across rat distal colon by cysteine. Frontiers in physiology 20120101
Effect of diuretic use on 30-day postdialysis mortality in critically ill patients receiving acute dialysis. PloS one 20120101
Suppression of adenosine-activated chloride transport by ethanol in airway epithelia. PloS one 20120101
A sensitive membrane-targeted biosensor for monitoring changes in intracellular chloride in neuronal processes. PloS one 20120101
Loop diuretics have anxiolytic effects in rat models of conditioned anxiety. PloS one 20120101
Multiple tyrosine metabolites are GPR35 agonists. Scientific reports 20120101
Excitatory GABA: How a Correct Observation May Turn Out to be an Experimental Artifact. Frontiers in pharmacology 20120101
Higher Blood Glucose within the Normal Range Is Associated with More Severe Strokes. Stroke research and treatment 20120101
Differentiated human midbrain-derived neural progenitor cells express excitatory strychnine-sensitive glycine receptors containing α2β subunits. PloS one 20120101
Lipoxin A4 stimulates calcium-activated chloride currents and increases airway surface liquid height in normal and cystic fibrosis airway epithelia. PloS one 20120101
Inhibition of Na(+)-K(+)-2Cl(-) cotransporter isoform 1 accelerates temozolomide-mediated apoptosis in glioblastoma cancer cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
High-grade glioma motility reduced by genetic knockdown of KCC3. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Blocking retinal chloride co-transporters KCC2 and NKCC: impact on direction selective ON and OFF responses in the rat's nucleus of the optic tract. PloS one 20120101
Expression of Na+-K+ -2Cl- cotransporter 1 is epigenetically regulated during postnatal development of hypertension. American journal of hypertension 20111201
Loss-of-function and gain-of-function phenotypes of stomatocytosis mutant RhAG F65S. American journal of physiology. Cell physiology 20111201
Inhibition of KCC2 in mouse spinal cord neurons leads to hypersensitivity to thermal stimulation. Anesthesia and analgesia 20111201
Pharmacological characterisation of apical Na+ and Cl- transport mechanisms of the anal papillae in the larval mosquito Aedes aegypti. The Journal of experimental biology 20111201
Dependence of corneal epithelial cell proliferation on modulation of interactions between ERK1/2 and NKCC1. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20111201
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS computational biology 20111201
Critical roles of transitional cells and Na/K-ATPase in the formation of vestibular endolymph. The Journal of neuroscience : the official journal of the Society for Neuroscience 20111116
With-No-Lysine Kinase 3 (WNK3) stimulates glioma invasion by regulating cell volume. American journal of physiology. Cell physiology 20111101
Role of NKCC in BK channel-mediated net K⁺ secretion in the CCD. American journal of physiology. Renal physiology 20111101
Triazacryptand-based fluorescent sensors for extracellular and intracellular K+ sensing. Biomaterials 20111101
Capsaicinoids regulate airway anion transporters through Rho kinase- and cyclic AMP-dependent mechanisms. American journal of respiratory cell and molecular biology 20111001
The flavonone naringenin inhibits chloride secretion in isolated colonic epithelia. European journal of pharmacology 20111001
Proteinase-activated receptors 1 and 2 exert opposite effects on renal renin release. Hypertension (Dallas, Tex. : 1979) 20111001
Chronic hyperosmotic stress converts GABAergic inhibition into excitation in vasopressin and oxytocin neurons in the rat. The Journal of neuroscience : the official journal of the Society for Neuroscience 20110914
A SPAK isoform switch modulates renal salt transport and blood pressure. Cell metabolism 20110907
Mechanisms of chloride in cardiomyocyte anoxia-reoxygenation injury: the involvement of oxidative stress and NF-kappaB activation. Molecular and cellular biochemistry 20110901
Anomalous levels of Cl- transporters cause a decrease of GABAergic inhibition in human peritumoral epileptic cortex. Epilepsia 20110901
Cellular localization of NKCC2 and its possible role in the Cl- absorption in the rat and human distal colonic epithelia. Translational research : the journal of laboratory and clinical medicine 20110901
Positive shifts of the GABAA receptor reversal potential due to altered chloride homeostasis is widespread after status epilepticus. Epilepsia 20110901
Efficacy of synaptic inhibition depends on multiple, dynamically interacting mechanisms implicated in chloride homeostasis. PLoS computational biology 20110901
WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters. The Journal of biological chemistry 20110826
Determination of transmembrane water fluxes in neurons elicited by glutamate ionotropic receptors and by the cotransporters KCC2 and NKCC1: a digital holographic microscopy study. The Journal of neuroscience : the official journal of the Society for Neuroscience 20110817
Pediatric cardiovascular drug dosing in critically ill children and extracorporeal membrane oxygenation. Journal of cardiovascular pharmacology 20110801
Ischemia-induced stimulation of Na-K-Cl cotransport in cerebral microvascular endothelial cells involves AMP kinase. American journal of physiology. Cell physiology 20110801
Complications of nephrotic syndrome. Korean journal of pediatrics 20110801
Primary afferent terminals acting as excitatory interneurons contribute to spontaneous motor activities in the immature spinal cord. The Journal of neuroscience : the official journal of the Society for Neuroscience 20110713
Effects of estradiol on ischemic factor-induced astrocyte swelling and AQP4 protein abundance. American journal of physiology. Cell physiology 20110701
Ion transport mechanisms linked to bicarbonate secretion in the esophageal submucosal glands. American journal of physiology. Regulatory, integrative and comparative physiology 20110701
Entacapone promotes cAMP-dependent colonic Cl(-) secretion in rats. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20110701
Astrocyte ERK phosphorylation precedes K(+)-induced swelling but follows hypotonicity-induced swelling. Neuropathology : official journal of the Japanese Society of Neuropathology 20110601
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Antiepileptic effects of endogenous beta-hydroxybutyrate in suckling infant rats. Epilepsy research 20110601
Volume regulation in mammalian skeletal muscle: the role of sodium-potassium-chloride cotransporters during exposure to hypertonic solutions. The Journal of physiology 20110601
Different effects of α-chloralose on spontaneous and evoked GABA release in rat hippocampal CA1 neurons. Brain research bulletin 20110530
Modulation of Na+/Mg²+ exchanger stoichiometry ratio by Cl⁻ ions in basolateral rat liver plasma membrane vesicles. Molecular and cellular biochemistry 20110501
Na-K-Cl cotransporter-1 in the mechanism of cell swelling in cultured astrocytes after fluid percussion injury. Journal of neurochemistry 20110501
A claim for caution in the use of promising bumetanide to treat neonatal seizures. Journal of child neurology 20110501
Sensitive isotope dilution liquid chromatography/tandem mass spectrometry method for quantitative analysis of bumetanide in serum and brain tissue. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110415
Functional plasticity of mitochondrion-rich cells in the skin of euryhaline medaka larvae (Oryzias latipes) subjected to salinity changes. American journal of physiology. Regulatory, integrative and comparative physiology 20110401
Differential regulation of NFAT5 by NKCC2 isoforms in medullary thick ascending limb (mTAL) cells. American journal of physiology. Renal physiology 20110401
Mechanisms of chloride uptake in frog olfactory receptor neurons. Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20110401
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Lubiprostone activates Cl- secretion via cAMP signaling and increases membrane CFTR in the human colon carcinoma cell line, T84. Digestive diseases and sciences 20110201
Lubiprostone reverses the inhibitory action of morphine on mucosal secretion in human small intestine. Digestive diseases and sciences 20110201
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Cell volume regulation following hypotonic shock in hepatocytes isolated from Sparus aurata. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20110101
Propionate-induced epithelial K(+) and Cl(-)/HCO3(-) secretion and free fatty acid receptor 2 (FFA2, GPR43) expression in the guinea pig distal colon. Pflugers Archiv : European journal of physiology 20110101
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Resistant hypertension workup and approach to treatment. International journal of hypertension 20110101
Functional analysis of human sodium-phosphate transporter 4 (NPT4/SLC17A3) polymorphisms. Journal of pharmacological sciences 20110101
NKCC1 controls GABAergic signaling and neuroblast migration in the postnatal forebrain. Neural development 20110101
Glucose depletion in the airway surface liquid is essential for sterility of the airways. PloS one 20110101
The effects of topical sodium cromoglicate on itch and flare in human skin induced by intradermal histamine: a randomised double-blind vehicle controlled intra-subject design trial. BMC research notes 20110101
Role of the kidneys in resistant hypertension. International journal of hypertension 20110101
Phosphorylation and transport in the Na-K-2Cl cotransporters, NKCC1 and NKCC2A, compared in HEK-293 cells. PloS one 20110101
Newborn Analgesia Mediated by Oxytocin during Delivery. Frontiers in cellular neuroscience 20110101
Frog oocytes to unveil the structure and supramolecular organization of human transport proteins. PloS one 20110101
Spatial and temporal dynamics in the ionic driving force for GABA(A) receptors. Neural plasticity 20110101
Altered GABA signaling in early life epilepsies. Neural plasticity 20110101
Band 3 missense mutations and stomatocytosis: insight into the molecular mechanism responsible for monovalent cation leak. International journal of cell biology 20110101
Genetics and function of neocortical GABAergic interneurons in neurodevelopmental disorders. Neural plasticity 20110101
The K+ channel opener 1-EBIO potentiates residual function of mutant CFTR in rectal biopsies from cystic fibrosis patients. PloS one 20110101
Functional characterization of water transport and cellular localization of three aquaporin paralogs in the salmonid intestine. Frontiers in physiology 20110101
Synaptic conversion of chloride-dependent synapses in spinal nociceptive circuits: roles in neuropathic pain. Pain research and treatment 20110101
Is it safe to use a diuretic to treat seizures early in development ? Epilepsy currents 20110101
Current controversies in newer therapies to treat birth asphyxia. International journal of pediatrics 20110101
Effect of polyphenols on oxidative stress and mitochondrial dysfunction in neuronal death and brain edema in cerebral ischemia. International journal of molecular sciences 20110101
Chloride-led disruption of the intestinal mucous layer impedes Salmonella invasion: evidence for an 'enteric tear' mechanism. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101
GABA regulates the multidirectional tangential migration of GABAergic interneurons in living neonatal mice. PloS one 20110101
A systematic review on pharmacokinetic changes in critically ill patients: role of extracorporeal membrane oxygenation. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101
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The effect of a clinical pharmacist discharge service on medication discrepancies in patients with heart failure. Pharmacy world & science : PWS 20101201
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals 20101201
Intrathecal administration of a gap junction decoupler, an inhibitor of Na(+)-K(+)-2Cl(-) cotransporter 1, or a GABA(A) receptor agonist attenuates mechanical pain hypersensitivity induced by REM sleep deprivation in the rat. Pharmacology, biochemistry, and behavior 20101201
Ammonium influx pathways into astrocytes and neurones of hippocampal slices. Journal of neurochemistry 20101201
Role of the NKCC1 co-transporter in sensitization of spinal nociceptive neurons. Pain 20101201
Human sodium phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate. The Journal of biological chemistry 20101105
Differential regulation of the bumetanide-sensitive cotransporter (NKCC2) by ovarian hormones. Steroids 20101101
SPAK-knockout mice manifest Gitelman syndrome and impaired vasoconstriction. Journal of the American Society of Nephrology : JASN 20101101
Cotransport of water by the Na+-K+-2Cl(-) cotransporter NKCC1 in mammalian epithelial cells. The Journal of physiology 20101101
Altered electrolyte handling of the choroid plexus in rats with glycerol-induced acute renal failure. Biopharmaceutics & drug disposition 20101101
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & medicinal chemistry letters 20101101
Potentiation of epithelial innate host responses by intercellular communication. PLoS pathogens 20101101
Congestive heart failure in Indians: how do we improve diagnosis & management? The Indian journal of medical research 20101101
Molecular mechanisms of microvascular failure in central nervous system injury--synergistic roles of NKCC1 and SUR1/TRPM4. Journal of neurosurgery 20100901
Endoplasmic reticulum Ca2+ signaling and mitochondrial Cyt c release in astrocytes following oxygen and glucose deprivation. Journal of neurochemistry 20100901
Sodium-bicarbonate cotransporter NBCn1 in the kidney medullary thick ascending limb cell line is upregulated under acidic conditions and enhances ammonium transport. Experimental physiology 20100901
Progressive NKCC1-dependent neuronal chloride accumulation during neonatal seizures. The Journal of neuroscience : the official journal of the Society for Neuroscience 20100901
[Simultaneous determination of five illegal drugs in weight control foods with solid phase extraction-high performance liquid chromatography]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20100901
Insulin induces swelling-dependent activation of the epidermal growth factor receptor in rat liver. The Journal of biological chemistry 20100820
Expression of Na-K-Cl cotransporter and edema formation are age dependent after ischemic stroke. Experimental neurology 20100801
Na(+)-K (+)-2Cl (-) cotransport inhibitor attenuates cerebral edema following experimental stroke via the perivascular pool of aquaporin-4. Neurocritical care 20100801
Loop diuretics for heart failure-associated hyponatremia. The American journal of medicine 20100801
Depolarizing shift in the GABA-induced current reversal potential by lidocaine hydrochloride. Brain research 20100723
Traditional Chinese formula, lubricating gut pill, improves loperamide-induced rat constipation involved in enhance of Cl- secretion across distal colonic epithelium. Journal of ethnopharmacology 20100720
Localization and functional characterization of the human NKCC2 isoforms. Acta physiologica (Oxford, England) 20100701
A key role for membrane transporter NKCC1 in mediating chondrocyte volume increase in the mammalian growth plate. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20100701
Role of membrane sialic acid and glycophorin protein in thorium induced aggregation and hemolysis of human erythrocytes. Biochimie 20100701
Sensitive phosphorimetric determination of bumetanide in human urine with its inhibition effect on the formation of [Fe-morin]3+ complex. Journal of fluorescence 20100701
Modulation of NaCl absorption by [HCO(3)(-)] in the marine teleost intestine is mediated by soluble adenylyl cyclase. American journal of physiology. Regulatory, integrative and comparative physiology 20100701
Basolateral Cl- uptake mechanisms in Xenopus laevis lung epithelium. American journal of physiology. Regulatory, integrative and comparative physiology 20100701
Proteinase-activated receptors-1 and 2 induce electrogenic Cl- secretion in the mouse cecum by distinct mechanisms. American journal of physiology. Gastrointestinal and liver physiology 20100701
Mucus secretion from individual submucosal glands of the ferret trachea. American journal of physiology. Lung cellular and molecular physiology 20100701
Stimulation of human and mouse erythrocyte Na(+)-K(+)-2Cl(-) cotransport by osmotic shrinkage does not involve AMP-activated protein kinase, but is associated with STE20/SPS1-related proline/alanine-rich kinase activation. The Journal of physiology 20100701
Inhibition of the Sodium-Potassium-Chloride Cotransporter Isoform-1 reduces glioma invasion. Cancer research 20100701
Evaluation of development-specific targets for antiepileptogenic therapy using rapid kindling. Epilepsia 20100701
Disease-modifying effects of phenobarbital and the NKCC1 inhibitor bumetanide in the pilocarpine model of temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience 20100623
Oxytocin is neuroprotective against oxygen-glucose deprivation and reoxygenation in immature hippocampal cultures. Neuroscience letters 20100614
Heterologous regulation of anion transporters by menthol in human airway epithelial cells. European journal of pharmacology 20100610
Strain-dependent differences in electrogenic secretion of electrolytes across mouse colon epithelium. Experimental physiology 20100601
The effect of brimonidine on transepithelial resistance in a human retinal pigment epithelial cell line. Korean journal of ophthalmology : KJO 20100601
Role of NKCC1 and KCC2 in the development of chronic neuropathic pain following spinal cord injury. Annals of the New York Academy of Sciences 20100601
Differential cell sensitivity between OTA and LPS upon releasing TNF-α. Toxins 20100601
Promoter hypomethylation upregulates Na+-K+-2Cl- cotransporter 1 in spontaneously hypertensive rats. Biochemical and biophysical research communications 20100528
Regulatory volume increase in epithelial cells isolated from the mouse fourth ventricle choroid plexus involves Na(+)-H(+) exchange but not Na(+)-K(+)-2Cl(-) cotransport. Brain research 20100406
AE2 Cl-/HCO3- exchanger is required for normal cAMP-stimulated anion secretion in murine proximal colon. American journal of physiology. Gastrointestinal and liver physiology 20100401
Intracellular Na(+) and Ca(2+) modulation increases the tensile properties of developing engineered articular cartilage. Arthritis and rheumatism 20100401
Nitric oxide produced by endothelial nitric oxide synthase promotes diuresis. American journal of physiology. Regulatory, integrative and comparative physiology 20100401
Hymenolepis diminuta: Effect of infection on ion transport in colon and blood picture of rats. Experimental parasitology 20100301
Cerebral metabolic alterations in rats with diabetic ketoacidosis: effects of treatment with insulin and intravenous fluids and effects of bumetanide. Diabetes 20100301
Excitatory action of GABA in the terminal nerve gonadotropin-releasing hormone neurons. Journal of neurophysiology 20100301
Bumetanide alleviates epileptogenic and neurotoxic effects of sevoflurane in neonatal rat brain. Anesthesiology 20100301
The GPA-dependent, spherostomatocytosis mutant AE1 E758K induces GPA-independent, endogenous cation transport in amphibian oocytes. American journal of physiology. Cell physiology 20100201
Mechanisms of Ca2+-stimulated fluid secretion by porcine bronchial submucosal gland serous acinar cells. American journal of physiology. Lung cellular and molecular physiology 20100201
In the adult hippocampus, chronic nerve growth factor deprivation shifts GABAergic signaling from the hyperpolarizing to the depolarizing direction. The Journal of neuroscience : the official journal of the Society for Neuroscience 20100120
Developmental and functional studies of the SLC12 gene family members from Drosophila melanogaster. American journal of physiology. Cell physiology 20100101
Activity-mediated plasticity of GABA equilibrium potential in rat hippocampal CA1 neurons. Experimental neurology 20100101
Differential DNA methylation correlates with differential expression of angiogenic factors in human heart failure. PloS one 20100101
Prostaglandin E2-induced colonic secretion in patients with and without colorectal neoplasia. BMC gastroenterology 20100101
Bumetanide-induced enlargement of the rat intrastrial space and effects of a vasopressin type 2 antagonist. ORL; journal for oto-rhino-laryngology and its related specialties 20100101
Chloride ion modulates cell proliferation of human androgen-independent prostatic cancer cell. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101
Expression of the sodium potassium chloride cotransporter (NKCC1) and sodium chloride cotransporter (NCC) and their effects on rat lens transparency. Molecular vision 20100101
Contribution of GABAergic interneurons to the development of spontaneous activity patterns in cultured neocortical networks. Frontiers in cellular neuroscience 20100101
Temporal coding at the immature depolarizing GABAergic synapse. Frontiers in cellular neuroscience 20100101
Aquaporins: relevance to cerebrospinal fluid physiology and therapeutic potential in hydrocephalus. Cerebrospinal fluid research 20100101
A Single Amino Acid Substitution Makes WNK4 Susceptible to SB 203580 and SB 202190. The open medicinal chemistry journal 20100101
A brief history of the study of fish osmoregulation: the central role of the Mt. Desert Island Biological Laboratory. Frontiers in physiology 20100101
Control of GABA Release at Mossy Fiber-CA3 Connections in the Developing Hippocampus. Frontiers in synaptic neuroscience 20100101
Neuropeptides modulate compound postsynaptic potentials in basolateral amygdala. Neuroscience 20091229
Functional expression of the Na-K-2Cl cotransporter NKCC2 in mammalian cells fails to confirm the dominant-negative effect of the AF splice variant. The Journal of biological chemistry 20091218
Endolymphatic sodium homeostasis by extramacular epithelium of the saccule. The Journal of neuroscience : the official journal of the Society for Neuroscience 20091216
Quercetin stimulates Na+/K+/2Cl- cotransport via PTK-dependent mechanisms in human airway epithelium. American journal of respiratory cell and molecular biology 20091201
Thrombin potentiates D-aspartate efflux from cultured astrocytes under conditions of K+ homeostasis disruption. Journal of neurochemistry 20091201
Unilateral ureteral obstruction alters expression of acid-base transporters in rat kidney. The Journal of urology 20091201
Propofol facilitates glutamatergic transmission to neurons of the ventrolateral preoptic nucleus. Anesthesiology 20091201
Gastroenteritis with severe consequences: a case of sotalol-induced torsades de pointes. Acta cardiologica 20091201
Vectorial bicarbonate transport by Par-C10 salivary cells. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20091201
Gynecomastia: An ADR due to drug interaction. Indian journal of pharmacology 20091201
The multi-herbal drug STW 5 (Iberogast) has prosecretory action in the human intestine. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20091101
Characteristics of Cl- uptake in rat alveolar type I cells. American journal of physiology. Lung cellular and molecular physiology 20091101
Bicarbonate transport by the human pancreatic ductal cell line HPAF. Pancreas 20091101
A comprehensive review of the loop diuretics: should furosemide be first line? The Annals of pharmacotherapy 20091101
Chloride transport in mitochondrion-rich cells of euryhaline tilapia (Oreochromis mossambicus) larvae. American journal of physiology. Cell physiology 20091001
GABAergic signaling induces divergent neuronal Ca2+ responses in the suprachiasmatic nucleus network. The European journal of neuroscience 20091001
Differences in cortical versus subcortical GABAergic signaling: a candidate mechanism of electroclinical uncoupling of neonatal seizures. Neuron 20090910
Excitatory GABAergic activation of cortical dividing glial cells. Cerebral cortex (New York, N.Y. : 1991) 20090901
Bumetanide inhibits rapid kindling in neonatal rats. Epilepsia 20090901
Genistein stimulates electrogenic Cl- secretion via phosphodiesterase modulation in the mouse jejunum. American journal of physiology. Cell physiology 20090901
Normal mouse intestinal mucus release requires cystic fibrosis transmembrane regulator-dependent bicarbonate secretion. The Journal of clinical investigation 20090901
Nkcc1 (Slc12a2) is required for the regulation of endolymph volume in the otic vesicle and swim bladder volume in the zebrafish larva. Development (Cambridge, England) 20090815
Structural and functional changes of the duodenum in human norovirus infection. Gut 20090801
GABAA receptors mediate excitation in adult rat GnRH neurons. Biology of reproduction 20090801
Cerebral microvascular endothelial cell Na/H exchange: evidence for the presence of NHE1 and NHE2 isoforms and regulation by arginine vasopressin. American journal of physiology. Cell physiology 20090801
Secretagogues stimulate electrogenic HCO3- secretion in the ileum of the brushtail possum, Trichosurus vulpecula: evidence for the role of a Na+/HCO3- cotransporter. The Journal of experimental biology 20090801
Inhibitory actions of the gamma-aminobutyric acid in pediatric Sturge-Weber syndrome. Annals of neurology 20090801
Ammonium-evoked alterations in intracellular sodium and pH reduce glial glutamate transport activity. Glia 20090701
HCO 3--dependent volume regulation in alpha-cells of the rat endocrine pancreas. Pflugers Archiv : European journal of physiology 20090701
NH4+ secretion in the avian colon. An actively regulated barrier to ammonium permeation of the colon mucosa. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20090701
The role of chloride transport in the control of the membrane potential in skeletal muscle--theory and experiment. Biophysical chemistry 20090701
Inhibition of aquaporin-1 and aquaporin-4 water permeability by a derivative of the loop diuretic bumetanide acting at an internal pore-occluding binding site. Molecular pharmacology 20090701
An environmentally friendly reflectometric method for bumetanide determination in pharmaceuticals. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20090701
CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium. PLoS biology 20090701
Harvesting candidate genes responsible for serious adverse drug reactions from a chemical-protein interactome. PLoS computational biology 20090701
Calciphylaxis in chronic renal failure: An approach to risk factors. Indian journal of nephrology 20090701
In situ measurement of airway surface liquid [K+] using a ratioable K+-sensitive fluorescent dye. The Journal of biological chemistry 20090605
Bumetanide, an NKCC1 antagonist, does not prevent formation of epileptogenic focus but blocks epileptic focus seizures in immature rat hippocampus. Journal of neurophysiology 20090601
Compensatory enhancement of intrinsic spiking upon NKCC1 disruption in neonatal hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience 20090527
Decreased seizure activity in a human neonate treated with bumetanide, an inhibitor of the Na(+)-K(+)-2Cl(-) cotransporter NKCC1. Journal of child neurology 20090501
Bumetanide for neonatal seizures: Based on evidence or enthusiasm? Epilepsia 20090501
Differential contribution of the Na(+)-K(+)-2Cl(-) cotransporter NKCC1 to chloride handling in rat embryonic dorsal root ganglion neurons and motor neurons. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090401
Low salt concentrations activate AMP-activated protein kinase in mouse macula densa cells. American journal of physiology. Renal physiology 20090401
Presynaptic glycine receptors facilitate spontaneous glutamate release onto hilar neurons in the rat hippocampus. Journal of neurochemistry 20090401
Nerve Terminal GABAA Receptors Activate Ca2+/Calmodulin-dependent Signaling to Inhibit Voltage-gated Ca2+ Influx and Glutamate Release. The Journal of biological chemistry 20090327
Inhibitions of chloride transport and gap junction reduce fluid flow across the whole porcine ciliary epithelium. Investigative ophthalmology & visual science 20090301
The role of chloride channels in rat corpus cavernosum: in vivo study. The journal of sexual medicine 20090301
At immature mossy-fiber-CA3 synapses, correlated presynaptic and postsynaptic activity persistently enhances GABA release and network excitability via BDNF and cAMP-dependent PKA. The Journal of neuroscience : the official journal of the Society for Neuroscience 20090225
Excitation-contraction coupling in resistance mesenteric arteries: evidence for NKCC1-mediated pathway. Biochemical and biophysical research communications 20090220
Intracellular pH regulation in human Sertoli cells: role of membrane transporters. Reproduction (Cambridge, England) 20090201
NKCC1 and AE3 appear to accumulate chloride in embryonic motoneurons. Journal of neurophysiology 20090201
Chloride accumulation drives volume dynamics underlying cell proliferation and migration. Journal of neurophysiology 20090201
NKCC1 (SLC12a2) induces a secondary axis in Xenopus laevis embryos independently of its co-transporter function. The Journal of physiology 20090201
Linking binge alcohol-induced neurodamage to brain edema and potential aquaporin-4 upregulation: evidence in rat organotypic brain slice cultures and in vivo. Journal of neurotrauma 20090201
Diuresis in renal failure: treat the patient, not the urine output. Critical care medicine 20090201
TEA-induced long-term potentiation at hippocampal mossy fiber-CA3 synapses: characteristics of its induction and expression. Brain research 20090109
Random stimulation of spider mechanosensory neurons reveals long-lasting excitation by GABA and muscimol. Journal of neurophysiology 20090101
Inhibition of chloride outward transport by gadolinium in cultured rat spinal cord neurons. Neurotoxicology 20090101
The management of acute heart failure and diuretic therapy. American journal of therapeutics 20090101
Astrocytic mechanisms explaining neural-activity-induced shrinkage of extraneuronal space. PLoS computational biology 20090101
Adverse drug reactions in hospital in-patients: a prospective analysis of 3695 patient-episodes. PloS one 20090101
At immature mossy fibers-CA3 connections, activation of presynaptic GABA(B) receptors by endogenously released GABA contributes to synapses silencing. Frontiers in cellular neuroscience 20090101
Expression levels of the alpha4 subunit of the GABA(A) receptor in differentiated neuroblastoma cells are correlated with GABA-gated current. Neuropharmacology 20090101
HCO3-dependent impact of Na+,K+,2Cl- cotransport in vascular smooth muscle excitation-contraction coupling. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20090101
The influence of commonly used immunosuppressive drugs on the small bowel functions - a comparative experimental study. Annals of transplantation 20090101
Effect of L-ascorbate on chloride transport in freshly excised sinonasal epithelia. American journal of rhinology & allergy 20090101
Toluene diisocyanate caused electrophysiological disturbances in the upper airways wall. International journal of occupational medicine and environmental health 20090101
Management of ascites due to gastrointestinal malignancy. Annals of Saudi medicine 20090101
Secondhand smoke inhibits both Cl- and K+ conductances in normal human bronchial epithelial cells. Respiratory research 20090101
Inflammatory bowel disease, such as Ulcerative colitis, is a risk factor for recurrent thromboembolic events: a case report. Cases journal 20090101
Age- and dose-specific anticonvulsant action of bumetanide in immature rats. Physiological research 20090101
Ionic support of the cough reflex. Annales Academiae Medicae Stetinensis 20090101
Clinical approach in treatment of resistant hypertension. Integrated blood pressure control 20090101
Chloride Is essential for capacitation and for the capacitation-associated increase in tyrosine phosphorylation. The Journal of biological chemistry 20081219
Na-K-Cl Cotransporter-1 in the mechanism of ammonia-induced astrocyte swelling. The Journal of biological chemistry 20081205
Analysis of exercise-induced Na+-K+ exchange in rat skeletal muscle in vivo. Experimental physiology 20081201
Effect of hypouricaemic and hyperuricaemic drugs on the renal urate efflux transporter, multidrug resistance protein 4. British journal of pharmacology 20081201
Sustained depolarizing shift of the GABA reversal potential by glutamate receptor activation in hippocampal neurons. Neuroscience research 20081201
Does the intracellular ionic concentration or the cell water content (cell volume) determine the activity of TonEBP in NIH3T3 cells? American journal of physiology. Cell physiology 20081201
GABA(B) receptor activation mediates frequency-dependent plasticity of developing GABAergic synapses. Nature neuroscience 20081201
Simultaneous measurement of mechanical responses and transepithelial potential difference and resistance, in guinea-pig isolated, perfused trachea using a novel apparatus: pharmacological characterization. European journal of pharmacology 20081119
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry 20081113
Use of photosensitising diuretics and risk of skin cancer: a population-based case-control study. British journal of cancer 20081104
Escherichia coli EAST1 toxin toxicity of variants 17-2 and O 42. Comparative immunology, microbiology and infectious diseases 20081101
Glycine input induces the synaptic facilitation in salamander rod photoreceptors. Journal of biomedical science 20081101
Dual pathway activated by tert-butyl hydroperoxide in human airway anion secretion. The Journal of pharmacology and experimental therapeutics 20081101
A K(+)/H (+) P-ATPase transport in the accessory cell membrane of the blowfly taste chemosensilla sustains the transepithelial potential. Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20081101
Iron accumulation in bronchial epithelial cells is dependent on concurrent sodium transport. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20081001
Bradykinin regulates human colonic ion transport in vitro. British journal of pharmacology 20081001
Cerebral blood flow and cerebral edema in rats with diabetic ketoacidosis. Diabetes 20081001
EP4 and EP2 receptor subtypes involved in colonic secretion in rat. Basic & clinical pharmacology & toxicology 20080901
Determination of diuretics in human urine by hollow fiber-based liquid-liquid-liquid microextraction coupled to high performance liquid chromatography. The Analyst 20080901
The bumetanide-sensitive Na-K-2Cl cotransporter NKCC1 as a potential target of a novel mechanism-based treatment strategy for neonatal seizures. Neurosurgical focus 20080901
Role of pontine neurons in central O(2) chemoreflex during development in bullfrogs (Lithobates catesbeiana). Neuroscience 20080826
Anionic selectivity sequence of the Cl(-)-H+ symporter in the synaptosomal preparation from rat brain cortex. Neurochemical research 20080801
Layer-specific generation and propagation of seizures in slices of developing neocortex: role of excitatory GABAergic synapses. Journal of neurophysiology 20080801
Excitatory GABA in rodent developing neocortex in vitro. Journal of neurophysiology 20080801
Decompensation of chronic heart failure associated with pregabalin in a 73-year-old patient with postherpetic neuralgia: a case report. British journal of clinical pharmacology 20080801
Endoplasmic reticulum Ca2+ dysregulation and endoplasmic reticulum stress following in vitro neuronal ischemia: role of Na+-K+-Cl- cotransporter. Journal of neurochemistry 20080801
Carbonic anhydrase inhibitors. Sulfonamide diuretics revisited--old leads for new applications? Organic & biomolecular chemistry 20080721
Capillary electrophoresis of diuretics and probenecid in methanol. Journal of chromatography. A 20080711
Posttraumatic GABA(A)-mediated [Ca2+]i increase is essential for the induction of brain-derived neurotrophic factor-dependent survival of mature central neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 20080702
Na+,K+,2Cl- cotransport and intracellular chloride regulation in rat primary sensory neurons: thermodynamic and kinetic aspects. Journal of neurophysiology 20080701
Roles of basolateral solute uptake via NKCC1 and of myosin II in vasopressin-induced cell swelling in inner medullary collecting duct. American journal of physiology. Renal physiology 20080701
An online field-amplification sample stacking method for the determination of diuretics in urine by capillary electrophoresis-amperometric detection. Talanta 20080630
Activation of chloride secretion via proteinase-activated receptor 2 in a human eccrine sweat gland cell line--NCL-SG3. Experimental dermatology 20080601
Effect of basolateral adenosine triphosphate on chloride secretion by bovine oviductal epithelium. Biology of reproduction 20080601
Purinergic inhibition of Na⁺,K⁺,Cl⁻ cotransport in C11-MDCK cells: Role of stress-activated protein kinases. Purinergic signalling 20080601
Induction of Na+/K+/2Cl- cotransporter expression mediates chronic potentiation of intestinal epithelial Cl- secretion by EGF. American journal of physiology. Cell physiology 20080601
Regulation of electrolyte transport across cultured endometrial epithelial cells by prolactin. The Journal of endocrinology 20080601
The association between high-dose diuretics and clinical stability in ambulatory chronic heart failure patients. Journal of cardiac failure 20080601
Overview of the proton-coupled MCT (SLC16A) family of transporters: characterization, function and role in the transport of the drug of abuse gamma-hydroxybutyric acid. The AAPS journal 20080601
Atelectasis induced by thoracotomy causes lung injury during mechanical ventilation in endotoxemic rats. Journal of Korean medical science 20080601
Intracellular and extracellular renin have opposite effects on the regulation of heart cell volume. Implications for myocardial ischaemia. Journal of the renin-angiotensin-aldosterone system : JRAAS 20080601
Excitatory actions of GABA in the suprachiasmatic nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience 20080521
GABA regulates excitatory synapse formation in the neocortex via NMDA receptor activation. The Journal of neuroscience : the official journal of the Society for Neuroscience 20080521
GABAA receptor-mediated activation of L-type calcium channels induces neuronal excitation in surgically resected human hypothalamic hamartomas. Epilepsia 20080501
Cerebral microvascular nNOS responds to lowered oxygen tension through a bumetanide-sensitive cotransporter and sodium-calcium exchanger. American journal of physiology. Heart and circulatory physiology 20080501
NKCC1 and KCC2 prevent hyperexcitability in the mouse hippocampus. Epilepsy research 20080501
[Epileptiform activities generated in vitro by human temporal lobe tissue]. Neuro-Chirurgie 20080501
Minimal volume regulation after shrinkage of red blood cells from five species of reptiles. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20080501
Coincident pre- and postsynaptic activity downregulates NKCC1 to hyperpolarize E(Cl) during development. The European journal of neuroscience 20080501
GABAergic depolarization of the axon initial segment in cortical principal neurons is caused by the Na-K-2Cl cotransporter NKCC1. The Journal of neuroscience : the official journal of the Society for Neuroscience 20080430
Effects of Cordyceps sinensis, Cordyceps militaris and their isolated compounds on ion transport in Calu-3 human airway epithelial cells. Journal of ethnopharmacology 20080417
Carbonic anhydrase inhibitors. Interaction of indapamide and related diuretics with 12 mammalian isozymes and X-ray crystallographic studies for the indapamide-isozyme II adduct. Bioorganic & medicinal chemistry letters 20080415
Rutaecarpine induces chloride secretion across rat isolated distal colon. The Journal of pharmacology and experimental therapeutics 20080401
Anion secretion evoked by Pasteurella multocida toxin across rat colon. European journal of pharmacology 20080331
The mechanisms of acute ischemic injury in the cell processes of developing white matter astrocytes. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20080301
Rapid hair cell loss: a mouse model for cochlear lesions. Journal of the Association for Research in Otolaryngology : JARO 20080301
Apparent intermediate K conductance channel hyposmotic activation in human lens epithelial cells. American journal of physiology. Cell physiology 20080301
NKCC1-mediated traumatic brain injury-induced brain edema and neuron death via Raf/MEK/MAPK cascade. Critical care medicine 20080301
GABA(A) receptors in normal development and seizures: friends or foes? Current neuropharmacology 20080301
NKCC1 cotransporter inactivation underlies embryonic development of chloride-mediated inhibition in mouse spinal motoneuron. The Journal of physiology 20080215
Thermodynamic regulation of NKCC1-mediated Cl- cotransport underlies plasticity of GABA(A) signaling in neonatal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 20080206
Bumetanide enhances phenobarbital efficacy in a neonatal seizure model. Annals of neurology 20080201
Pharmacologic approaches for volume excess in acute kidney injury (AKI). The International journal of artificial organs 20080201
E-Ring Isoprostanes Stimulate a Cl Conductance in Airway Epithelium via Prostaglandin E2-Selective Prostanoid Receptors. American journal of respiratory cell and molecular biology 20080101
Magnesium-calcium signalling in rat parotid acinar cells: effects of acetylcholine. Molecular and cellular biochemistry 20080101
Hypoxia effects on cell volume and ion uptake of cerebral microvascular endothelial cells. American journal of physiology. Cell physiology 20080101
Diuretics: from classical carbonic anhydrase inhibitors to novel applications of the sulfonamides. Current pharmaceutical design 20080101
Multiplicity of cerebrospinal fluid functions: New challenges in health and disease. Cerebrospinal fluid research 20080101
Regulation of endothelin-1 expression and function by nutrient stress in mouse colon epithelia. Scandinavian journal of gastroenterology 20080101
Elevated intracellular chloride level in albino visual cortex neurons is mediated by Na-K-Cl co-transporter. BMC neuroscience 20080101
Effects of oxytocin on GABA signalling in the foetal brain during delivery. Progress in brain research 20080101
Potassium channel and NKCC cotransporter involvement in ocular refractive control mechanisms. PloS one 20080101
Modulation of chloride homeostasis by inflammatory mediators in dorsal root ganglion neurons. Molecular pain 20080101
Acquisition of cisplatin-resistance in malignant mesothelioma cells abrogates Na+,K+,2Cl(-)-cotransport activity and cisplatin-induced early membrane blebbing. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101
Pump and channel K (Rb+) fluxes in apoptosis of human lymphoid cell line U937. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101
The role of cation-dependent chloride transporters in neuropathic pain following spinal cord injury. Molecular pain 20080101
Cellular mechanisms underlying the laxative effect of flavonol naringenin on rat constipation model. PloS one 20080101
Multichannel liquid chromatography-tandem mass spectrometry cocktail method for comprehensive substrate characterization of multidrug resistance-associated protein 4 transporter. Pharmaceutical research 20071201
Altered renal sodium transporter expression in an animal model of type 2 diabetes mellitus. Journal of Korean medical science 20071201
Translocator protein (18 kDa) ligand PK 11195 induces transient mitochondrial Ca2+ release leading to transepithelial Cl- secretion in HT-29 human colon cancer cells. Biology of the cell 20071101
HCO(-3)-dependent pHi recovery and overacidification induced by NH+4 pulse in rat lung alveolar type II cells: HCO(-3)-dependent NH3 excretion from lungs? Pflugers Archiv : European journal of physiology 20071101
Characterization of a long-term rat mTAL cell line. American journal of physiology. Renal physiology 20071001
[Cl-]i modulation of Ca2+-regulated exocytosis in ACh-stimulated antral mucous cells of guinea pig. American journal of physiology. Gastrointestinal and liver physiology 20071001
Transepithelial bioelectrical properties of rabbit acinar cell monolayers on polyester membrane scaffolds. American journal of physiology. Cell physiology 20071001
pH stat studies on bicarbonate secretion in the isolated mouse ileum. Biomedical research (Tokyo, Japan) 20071001
Mechanisms of neuronal chloride accumulation in intact mouse olfactory epithelium. The Journal of physiology 20070915
Perturbed chloride homeostasis and GABAergic signaling in human temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience 20070912
Combined effect of solvent content, temperature and pH on the chromatographic behaviour of ionisable compounds. Journal of chromatography. A 20070907
Beta-adrenergic activation of solute coupled water uptake by toad skin epithelium results in near-isosmotic transport. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20070901
Application of the Na+ recirculation theory to ion coupled water transport in low- and high resistance osmoregulatory epithelia. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20070901
SLC26A7 can function as a chloride-loading mechanism in parietal cells. Pflugers Archiv : European journal of physiology 20070901
Genetic variation in the renal sodium transporters NKCC2, NCC, and ENaC in relation to the effects of loop diuretic drugs. Clinical pharmacology and therapeutics 20070901
Model-specific effects of bumetanide on epileptiform activity in the in-vitro intact hippocampus of the newborn mouse. Neuropharmacology 20070901
Regions in the cytosolic C-terminus of the secretory Na(+)-K(+)-2Cl(-) cotransporter NKCC1 are required for its homodimerization. Biochemistry 20070821
Effects of age-dependent membrane transport changes on the homeostasis of senescent human red blood cells. Blood 20070815
Kinetic properties of Cl uptake mediated by Na+-dependent K+-2Cl cotransport in immature rat neocortical neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 20070808
Nitric oxide production by mouse renal tubules can be increased by a sodium-dependent mechanism. Nitric oxide : biology and chemistry 20070801
Appearance of segmental discrepancy of anion transport in rat distal colon. Biological & pharmaceutical bulletin 20070801
Fast quantitative determination of diuretic drugs in tablets and human urine by microchip electrophoresis with native fluorescence detection. Electrophoresis 20070801
NKCC1 does not accumulate chloride in developing retinal neurons. Journal of neurophysiology 20070701
Oxygen-sensitive regulatory volume increase and Na transport in red blood cells from the cane toad, Bufo marinus. The Journal of experimental biology 20070701
NKCC1 phosphorylation stimulates neurite growth of injured adult sensory neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 20070620
Hypertonic shrinking but not hypotonic swelling increases sodium concentration in rat brain synaptosomes. Brain research bulletin 20070615
Electrogenic bicarbonate secretion by prairie dog gallbladder. American journal of physiology. Gastrointestinal and liver physiology 20070601
Norepinephrine, via beta-adrenoceptors, regulates bumetanide-sensitive cotransporter type 1 expression in thick ascending limb cells. Hypertension (Dallas, Tex. : 1979) 20070601
Effect of osmotic shrinkage and hormones on the expression of Na+/H+ exchanger-1, Na+/K+/2Cl- cotransporter and Na+/K+ -ATPase in gill pavement cells of freshwater adapted Japanese eel, Anguilla japonica. The Journal of experimental biology 20070601
Bumetanide administration attenuated traumatic brain injury through IL-1 overexpression. Neurological research 20070601
Extracellular glutamine is a critical modulator for regulatory volume increase in human glioma cells. Brain research 20070504
Effect of NYD-SP27 down-regulation on ATP-induced Ca2+-dependent pancreatic duct anion secretion in cystic fibrosis cells. Cell biology international 20070501
Shrinkage insensitivity of NKCC1 in myosin II-depleted cytoplasts from Ehrlich ascites tumor cells. American journal of physiology. Cell physiology 20070501
Effect of the Na-K-2Cl cotransporter NKCC1 on systemic blood pressure and smooth muscle tone. American journal of physiology. Heart and circulatory physiology 20070501
Replication of segment-specific and intercalated cells in the mouse renal collecting system. Histochemistry and cell biology 20070401
Mucus secretion by single tracheal submucosal glands from normal and cystic fibrosis transmembrane conductance regulator knockout mice. The Journal of physiology 20070401
Identification and functional characterization of cation-chloride cotransporters in plants. The Plant journal : for cell and molecular biology 20070401
Hospital policies for treatment of acute decompensated heart failure. The Annals of pharmacotherapy 20070401
The effects of bumetanide on human umbilical artery contractions. Reproductive sciences (Thousand Oaks, Calif.) 20070401
Role of Na+-K+-Cl- cotransport and Na+/Ca2+ exchange in mitochondrial dysfunction in astrocytes following in vitro ischemia. American journal of physiology. Cell physiology 20070301
Effects of inhibition of the Na+/K+/2Cl- cotransporter on myogenic and angiotensin II responses of the rat afferent arteriole. American journal of physiology. Renal physiology 20070301
NKCC1 activity modulates formation of functional inhibitory synapses in cultured neocortical neurons. Synapse (New York, N.Y.) 20070301
[Na+,K+,2Cl(-)-cotransport and chloride permeability of the cell membrane in mezaton and histamine regulation of electrical and contractile activity in smooth muscle cells from the guinea pig ureter]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20070301
Roles of volume-sensitive chloride channel in excitotoxic neuronal injury. The Journal of neuroscience : the official journal of the Society for Neuroscience 20070207
Recovery of mucosal barrier function in ischemic porcine ileum and colon is stimulated by a novel agonist of the ClC-2 chloride channel, lubiprostone. American journal of physiology. Gastrointestinal and liver physiology 20070201
Severe citrate toxicity complicating volunteer apheresis platelet donation. Journal of clinical apheresis 20070201
Depolarization evoked by acetylcholine in mesenteric arteries of hypertensive rats attenuates endothelium-dependent hyperpolarizing factor. Journal of hypertension 20070201
Estimating the impact of adding C-reactive protein as a criterion for lipid lowering treatment in the United States. Journal of general internal medicine 20070201
Non-genomic effects of aldosterone on intracellular ion regulation and cell volume in rat ventricular myocytes. Canadian journal of physiology and pharmacology 20070201
Altered ion transport and responsiveness to methacholine and hyperosmolarity in air interface-cultured guinea-pig tracheal epithelium. Journal of pharmacological and toxicological methods 20070101
Fluid transport across the isolated porcine ciliary epithelium. Investigative ophthalmology & visual science 20070101
Early onset pauciarticular arthritis is the major risk factor for naproxen-induced pseudoporphyria in juvenile idiopathic arthritis. Arthritis research & therapy 20070101
Investigation of the Ba2+-sensitive NH4+ transport pathways in the apical cell membrane of primary cultured rabbit MTAL cells. Nephron. Physiology 20070101
Characterization of glial cell K-Cl cotransport. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101
Spinal NKCC1 blockade inhibits TRPV1-dependent referred allodynia. Molecular pain 20070101
Suspension of disbelief - or the Bumetanide paradox. Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20070101
[Hypotonic swelling activates the Na*/H* exchange in rat brain synaptosomes]. Biofizika 20070101
Effect of hibernation on sodium and chloride ion transport in isolated frog skin. Folia biologica 20070101
Colonic epithelial ion transport is not affected in patients with diverticulosis. BMC gastroenterology 20070101
Multiple functions of cation-chloride cotransporters in the fish retina. Visual neuroscience 20070101
An exploratory study with an adaptive continuous intravenous furosemide regimen in neonates treated with extracorporeal membrane oxygenation. Critical care (London, England) 20070101
Cytopathic mechanisms of HIV-1. Virology journal 20070101
Detection of bumetanide in an over-the-counter dietary supplement. Journal of analytical toxicology 20070101
Role of chloride transport proteins in the vasorelaxant action of nitroprusside in isolated rat aorta. European journal of pharmacology 20061228
The role of potassium chloride cotransporters in murine and human sperm volume regulation. Biology of reproduction 20061201
Fast gas chromatographic/mass spectrometric determination of diuretics and masking agents in human urine: Development and validation of a productive screening protocol for antidoping analysis. Journal of chromatography. A 20061201
Early embryonic renal tubules of wild-type and polycystic kidney disease kidneys respond to cAMP stimulation with cystic fibrosis transmembrane conductance regulator/Na(+),K(+),2Cl(-) Co-transporter-dependent cystic dilation. Journal of the American Society of Nephrology : JASN 20061201
Chloride secretion by porcine ciliary epithelium: New insight into species similarities and differences in aqueous humor formation. Investigative ophthalmology & visual science 20061201
Chloride-dependent intracellular pH regulation via extracellular calcium-sensing receptor in the medullary thick ascending limb of the mouse kidney. The Tohoku journal of experimental medicine 20061201
Potential role of abnormal ion transport in the pathogenesis of chronic sinusitis. Archives of otolaryngology--head & neck surgery 20061201
Dose-dependent association between use of loop diuretics and mortality in advanced systolic heart failure. The American journal of cardiology 20061115
Effect of complete protein 4.1R deficiency on ion transport properties of murine erythrocytes. American journal of physiology. Cell physiology 20061101
Increased expression and function of the myocardial Na-K-2Cl cotransporter in failing rat hearts. Basic research in cardiology 20061101
Inhibitory postsynaptic potentials in lumbar motoneurons remain depolarizing after neonatal spinal cord transection in the rat. Journal of neurophysiology 20061101
Regulatory volume increase (RVI) by in situ and isolated bovine articular chondrocytes. Journal of cellular physiology 20061101
Inhibition of the Na+ -K+ -2Cl- -cotransporter in choroid plexus attenuates traumatic brain injury-induced brain edema and neuronal damage. European journal of pharmacology 20061024
Estradiol reduces activity of the blood-brain barrier Na-K-Cl cotransporter and decreases edema formation in permanent middle cerebral artery occlusion. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20061001
Antiepileptic effect of loop diuretics? Comment to 'Differential effects of cation-chloride co-transport-blocking diuretics in a rat hippocampal slice model of epilepsy' by Margineanu, Klitgaard, Epilepsy Res. 69 (2006) 93-99. Epilepsy research 20061001
Up-regulation of fetal rat lung parathyroid hormone-related protein gene regulatory network down-regulates the Sonic Hedgehog/Wnt/betacatenin gene regulatory network. Pediatric research 20061001
Efficacy and safety of a furosemide continuous infusion following cardiac surgery. The Annals of pharmacotherapy 20061001
Effects of high-K+, Na+-deficient solution on contractility of the smooth muscles of the bovine trachea. The Journal of veterinary medical science 20061001
Activation of sodium transport in rat erythrocytes by inhibition of protein phosphatases 1 and 2A. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20060901
Cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel and Na-K-Cl cotransporter NKCC1 isoform mediate the vasorelaxant action of genistein in isolated rat aorta. European journal of pharmacology 20060821
Two different oxygen sensors regulate oxygen-sensitive K+ transport in crucian carp red blood cells. The Journal of physiology 20060815
Na+ -K+ -2Cl- cotransporter is implicated in gender differences in the response of the rat aorta to phenylephrine. British journal of pharmacology 20060801
The hydroosmotic response of frog urinary bladder to serosal hypertonicity is dependent on adenylate cyclase for its maintenance and affected by [Cl-]o changes. American journal of physiology. Regulatory, integrative and comparative physiology 20060701
Paradoxical effects of hydrogen peroxide on human airway anion secretion. The Journal of pharmacology and experimental therapeutics 20060701
The pathophysiology of ischemic injury to developing white matter. McGill journal of medicine : MJM : an international forum for the advancement of medical sciences by students 20060701
The cation-chloride cotransporter NKCC1 promotes sharp waves in the neonatal rat hippocampus. The Journal of physiology 20060615
Relation of loop diuretic dose to mortality in advanced heart failure. The American journal of cardiology 20060615
Subtractive hybridization unravels a role for the ion cotransporter NKCC1 in the murine intestinal pacemaker. American journal of physiology. Gastrointestinal and liver physiology 20060601
PVD9902, a porcine vas deferens epithelial cell line that exhibits neurotransmitter-stimulated anion secretion and expresses numerous HCO3(-) transporters. American journal of physiology. Cell physiology 20060601
Role of the Na+-K+-2Cl- cotransporter in the development of capsaicin-induced neurogenic inflammation. Journal of neurophysiology 20060601
Reported medication use in the neonatal intensive care unit: data from a large national data set. Pediatrics 20060601
Activity of the renal Na+-K+-2Cl- cotransporter is reduced by mutagenesis of N-glycosylation sites: role for protein surface charge in Cl- transport. American journal of physiology. Renal physiology 20060501
Nitric oxide transiently converts synaptic inhibition to excitation in retinal amacrine cells. Journal of neurophysiology 20060501
Differential effects of cation-chloride co-transport-blocking diuretics in a rat hippocampal slice model of epilepsy. Epilepsy research 20060501
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Electrochemical gradients for Na+, K+, Cl- and H+ across the apical membrane in Malpighian (renal) tubule cells of Rhodnius prolixus. The Journal of experimental biology 20060501
Lack of threshold for anisotonic cell volume regulation. The Journal of membrane biology 20060501
Neurogenic secretion mediated by the purinergic P2Y1 receptor in guinea-pig small intestine. European journal of pharmacology 20060424
Talniflumate increases survival in a cystic fibrosis mouse model of distal intestinal obstructive syndrome. The Journal of pharmacology and experimental therapeutics 20060401
Restoration of mucociliary transport in the fluid-depleted trachea by surface-active instillates. American journal of respiratory cell and molecular biology 20060401
Dopamine-induced graded intracellular Ca2+ elevation via the Na+Ca2+ exchanger operating in the Ca2+-entry mode in cockroach salivary ducts. Cell calcium 20060401
Regulation of water permeability in rabbit conjunctival epithelium by anisotonic conditions. American journal of physiology. Cell physiology 20060401
Dosage dependent hormonal counter regulation to combination therapy in patients with left ventricular dysfunction. Journal of clinical pharmacy and therapeutics 20060401
Na+/K+/Cl- cotransporter activates MAP-kinase cascade downstream to protein kinase C, and upstream to MEK. Journal of cellular physiology 20060301
Membrane proteins involved in potassium shifts during muscle activity and fatigue. American journal of physiology. Regulatory, integrative and comparative physiology 20060301
Indirect laser-induced fluorescence detection of diuretics separated by capillary electrophoresis. Journal of separation science 20060301
Functional characterization of serotonin receptor subtypes in human duodenal secretion. Basic & clinical pharmacology & toxicology 20060201
The chloride transporter Na(+)-K(+)-Cl- cotransporter isoform-1 contributes to intracellular chloride increases after in vitro ischemia. The Journal of neuroscience : the official journal of the Society for Neuroscience 20060201
Regulation of potassium transport in human lens epithelial cells. Experimental eye research 20060101
DCEBIO stimulates Cl- secretion in the mouse jejunum. American journal of physiology. Cell physiology 20060101
Ionic mechanism of forskolin-induced liquid secretion by porcine bronchi. American journal of physiology. Lung cellular and molecular physiology 20060101
Chloride-sensitive MEQ fluorescence in chick embryo motoneurons following manipulations of chloride and during spontaneous network activity. Journal of neurophysiology 20060101
Fracture risk in patients treated with loop diuretics. Journal of internal medicine 20060101
Probable loop diuretic-induced pancreatitis in a sulfonamide-allergic patient. The Annals of pharmacotherapy 20060101
Loop diuretics increase bone turnover and decrease BMD in osteopenic postmenopausal women: results from a randomized controlled study with bumetanide. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20060101
Intracellular acidification in neurons induced by ammonium depends on KCC2 function. The European journal of neuroscience 20060101
[Diuretic therapy in heart failure]. Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20060101
Thyrotropin-releasing hormone in rat heart: effect of swelling, angiotensin II and renin gene. Acta physiologica (Oxford, England) 20060101
Mebeverine influences sodium ion transport in the distal colon. Pharmacological reports : PR 20060101
Evaluation of furosemide regimens in neonates treated with extracorporeal membrane oxygenation. Critical care (London, England) 20060101
The effect of serotonin on epinephrine modulation of transepithelial ion transport in isolated frog skin. Folia biologica 20060101
The electrical potential difference through the foot epithelium of the snail Achatina achatina, Lameere during mechanical and chemical stimulation. Folia biologica 20060101
The neurotransmitters glycine and GABA stimulate glucagon-like peptide-1 release from the GLUTag cell line. The Journal of physiology 20051215
Electrophysiological effects of O2*- on the plasma membrane in vascular endothelial cells. American journal of physiology. Heart and circulatory physiology 20051201
Moderate-to-severe ischemic conditions increase activity and phosphorylation of the cerebral microvascular endothelial cell Na+-K+-Cl- cotransporter. American journal of physiology. Cell physiology 20051201
Functional characterization of human monocarboxylate transporter 6 (SLC16A5). Drug metabolism and disposition: the biological fate of chemicals 20051201
The underlying cellular mechanism in the effect of tetramethylpyrazine on the anion secretion of colonic mucosa. The Japanese journal of physiology 20051201
Serotoninergic modulation of chloride homeostasis during maturation of the locomotor network in zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience 20051116
Mouse organic anion transporter 2 and 3 (mOAT2/3[Slc22a7/8]) mediates the renal transport of bumetanide. European journal of pharmacology 20051107
Activation of CFTR by ASBT-mediated bile salt absorption. American journal of physiology. Gastrointestinal and liver physiology 20051101
Functional characterization of rat organic anion transporter 5 (Slc22a19) at the apical membrane of renal proximal tubules. The Journal of pharmacology and experimental therapeutics 20051101
NKCC1 transporter facilitates seizures in the developing brain. Nature medicine 20051101
Cell volume regulation during hyperosmotic shrinkage is mediated by Na+/K+-ATPase and Na+-K+-2Cl- cotransporter in Necturus gastrics surface epithelial cells. Digestive diseases and sciences 20051101
Diuretic soothes seizures in newborns. Nature medicine 20051101
Quercetin and NPPB-induced diminution of aldosterone action on Na+ absorption and ENaC expression in renal epithelium. Biochemical and biophysical research communications 20051021
Water permeability of Na+-K+-2Cl- cotransporters in mammalian epithelial cells. The Journal of physiology 20051001
Glucose-induced electrical activity in rat pancreatic beta-cells: dependence on intracellular chloride concentration. The Journal of physiology 20051001
Duodenal secretion in humans mediated by the EP4 receptor subtype. Acta physiologica Scandinavica 20051001
Role of Na-K-2Cl cotransporter-1 in gastric secretion of nonacidic fluid and pepsinogen. American journal of physiology. Gastrointestinal and liver physiology 20050901
Effect of sodium ferulate on human colonic anion secretion and the underlying signaling mechanism. Biological & pharmaceutical bulletin 20050901
Characterization of regulatory volume behavior by fluorescence quenching in human corneal epithelial cells. The Journal of membrane biology 20050901
NKCC1 and NHE1 are abundantly expressed in the basolateral plasma membrane of secretory coil cells in rat, mouse, and human sweat glands. American journal of physiology. Cell physiology 20050801
Comparison of cannabidiol, antioxidants, and diuretics in reversing binge ethanol-induced neurotoxicity. The Journal of pharmacology and experimental therapeutics 20050801
Screening procedure for detection of diuretics and uricosurics and/or their metabolites in human urine using gas chromatography-mass spectrometry after extractive methylation. Therapeutic drug monitoring 20050801
Combination therapy with metolazone and loop diuretics in outpatients with refractory heart failure: an observational study and review of the literature. Cardiovascular drugs and therapy 20050801
Escherichia coli heat stable (STa) enterotoxin and the upper small intestine: lack of evidence in vivo for net fluid secretion. The Journal of membrane biology 20050701
Electrogenic H+ transport and pH gradients generated by a V-H+ -ATPase in the isolated perfused larval Drosophila midgut. The Journal of membrane biology 20050701
Inhibitors of cation-chloride-cotransporters affect hypoxic/hypoglycemic injury in hippocampal slices. Brain research 20050607
Activation of presynaptic GABAA receptors increases spontaneous glutamate release onto noradrenergic neurons of the rat locus coeruleus. Brain research 20050607
Effect of amiloride and bumetanide on transepithelial ion transport in isolated rabbit cecal and colonic wall. Postepy higieny i medycyny doswiadczalnej (Online) 20050603
Characterization of active ion transport across primary rabbit corneal epithelial cell layers (RCrECL) cultured at an air-interface. Experimental eye research 20050601
Interdependency of beta-adrenergic receptors and CFTR in regulation of alveolar active Na+ transport. Circulation research 20050513
Zinc inhibits cAMP-stimulated Cl secretion via basolateral K-channel blockade in rat ileum. American journal of physiology. Gastrointestinal and liver physiology 20050501
Transport mechanism and substrate specificity of human organic anion transporter 2 (hOat2 [SLC22A7]). The Journal of pharmacy and pharmacology 20050501
Modeling spontaneous activity in the developing spinal cord using activity-dependent variations of intracellular chloride. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050406
Muscarinic activation of Na+-dependent ion transporters and modulation by bicarbonate in rat submandibular gland acinus. American journal of physiology. Gastrointestinal and liver physiology 20050401
Rubidium-87 magnetic resonance spectroscopy and imaging for analysis of mammalian K+ transport. NMR in biomedicine 20050401
Impaired Cl- extrusion in layer V pyramidal neurons of chronically injured epileptogenic neocortex. Journal of neurophysiology 20050401
Molecular physiology and pathophysiology of electroneutral cation-chloride cotransporters. Physiological reviews 20050401
The role of Na-K-Cl co-transporter in cerebral ischemia. Neurological research 20050401
Differential effects of Na-K-ATPase pump inhibition, chemical anoxia, and glycolytic blockade on membrane potential of rat optic nerve. Brain research 20050310
Mechanisms of chloride influx during KCl-induced swelling in the chicken retina. Pflugers Archiv : European journal of physiology 20050301
Peripheral and central antinociceptive action of Na+-K+-2Cl- cotransporter blockers on formalin-induced nociception in rats. Pain 20050301
Differences between cation-chloride co-transporter functions in the visual cortex of pigmented and albino rats. The European journal of neuroscience 20050301
Mechanism of the excitatory Cl- response in mouse olfactory receptor neurons. Neuron 20050217
Life threatening hyperkalaemia with diarrhoea during ACE inhibition. Emergency medicine journal : EMJ 20050201
Bumetanide reduces cerebral edema formation in rats with diabetic ketoacidosis. Diabetes 20050201
Distinct properties of functional KCC2 expression in immature mouse hippocampal neurons in culture and in acute slices. The European journal of neuroscience 20050201
Sodium channels are required during in vivo sodium chloride hyperosmolarity to stimulate increase in intestinal endothelial nitric oxide production. American journal of physiology. Heart and circulatory physiology 20050101
GABA(A) receptor facilitation of neurokinin release from primary afferent terminals in the rat spinal cord. Neuroscience 20050101
Predominant constitutive CFTR conductance in small airways. Respiratory research 20050101
Na(+)-dependent chloride transporter (NKCC1)-null mice exhibit less gray and white matter damage after focal cerebral ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20050101
Pharmacological modulation of lung cancer cells for potassium ion depletion. Anticancer research 20050101
Effects of amiloride and bumetanide on hyperpolarization after movement across the distal colon epithelium. Pharmacological reports : PR 20050101
Role of Cl- in cerebral vascular tone and expression of Na+-K+-2Cl- co-transporter after neonatal hypoxia-ischemia. Canadian journal of physiology and pharmacology 20050101
The influence of ambroxol and capsaicin on the isolated rabbit bladder wall. Acta poloniae pharmaceutica 20050101
Chloride channels and alpha1-adrenoceptor-mediated pulmonary artery smooth muscle contraction: effect of pulmonary hypertension. European journal of pharmacology 20041215
Genistein stimulates electrogenic Cl(-) secretion in mouse jejunum. American journal of physiology. Cell physiology 20041201
Reducing chloride conductance prevents hyperkalaemia-induced loss of twitch force in rat slow-twitch muscle. The Journal of physiology 20041115
Acute study of interaction among cadmium, calcium, and zinc transport along the rat nephron in vivo. American journal of physiology. Renal physiology 20041101
Involvement of cytosolic Cl- in osmoregulation of alpha-ENaC gene expression. American journal of physiology. Renal physiology 20041101
A model for fluid secretion in Rhodnius upper Malpighian tubules (UMT). The Journal of membrane biology 20041101
Chloride efflux is involved in ET-1 and 5-HT-induced contraction in rabbit basilar artery. Journal of cardiovascular pharmacology 20041101
Na-K-Cl cotransporter-mediated intracellular Na+ accumulation affects Ca2+ signaling in astrocytes in an in vitro ischemic model. The Journal of neuroscience : the official journal of the Society for Neuroscience 20041027
Signalling mechanisms underlying the rapid and additive stimulation of NKCC activity by insulin and hypertonicity in rat L6 skeletal muscle cells. The Journal of physiology 20041001
Cell-volume-dependent vascular smooth muscle contraction: role of Na+, K+, 2Cl- cotransport, intracellular Cl- and L-type Ca2+ channels. Pflugers Archiv : European journal of physiology 20041001
Na+ competes with K+ in bumetanide-sensitive transport by Malpighian tubules of Rhodnius prolixus. The Journal of experimental biology 20041001
Purine modulation of cytokine release during diuretic therapy of rheumatoid arthritis. Nucleosides, nucleotides & nucleic acids 20041001
Process control and drug analysis with an on-line capillary electrophoresis system. Journal of biochemical and biophysical methods 20040930
Stimulation of renin release by prostaglandin E2 is mediated by EP2 and EP4 receptors in mouse kidneys. American journal of physiology. Renal physiology 20040901
Ion and diuretic specificity of chimeric proteins between apical Na(+)-K(+)-2Cl(-) and Na(+)-Cl(-) cotransporters. American journal of physiology. Renal physiology 20040901
Na-K-2Cl cotransporter inhibition impairs human lung cellular proliferation. American journal of physiology. Lung cellular and molecular physiology 20040901
Effects of dopamine on ion transport across the rat distal colon. Pflugers Archiv : European journal of physiology 20040901
Regulatory volume increase after secretory volume decrease in colonic epithelial cells under muscarinic stimulation. Pflugers Archiv : European journal of physiology 20040901
Improvement of barrier function and stimulation of colonic epithelial anion secretion by Menoease Pills. World journal of gastroenterology 20040901
Role of anions in nitric oxide-induced short-circuit current increase in isolated porcine ciliary processes. Investigative ophthalmology & visual science 20040901
Functional characterization of muscarinic receptor subtypes in human duodenal secretion. Acta physiologica Scandinavica 20040901
Bumetanide inhibition of the blood-brain barrier Na-K-Cl cotransporter reduces edema formation in the rat middle cerebral artery occlusion model of stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20040901
Cross-talk of phosphoinositide- and cyclic nucleotide-dependent signaling pathways in differentiating avian nasal gland cells. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20040801
Chloride transport inhibitors influence recovery from oxygen-glucose deprivation-induced cellular injury in adult hippocampus. Neuropharmacology 20040801
Acute ischemic injury of astrocytes is mediated by Na-K-Cl cotransport and not Ca2+ influx at a key point in white matter development. Journal of neuropathology and experimental neurology 20040801
Mechanism of acute ischemic injury of oligodendroglia in early myelinating white matter: the importance of astrocyte injury and glutamate release. Journal of neuropathology and experimental neurology 20040801
Effects of a new cystic fibrosis transmembrane conductance regulator inhibitor on Cl- conductance in human sweat ducts. Experimental physiology 20040701
Basolateral ion transport mechanisms during fluid secretion by Drosophila Malpighian tubules: Na+ recycling, Na+:K+:2Cl- cotransport and Cl- conductance. The Journal of experimental biology 20040701
Regulation of ion transport by 5-hydroxytryptamine in rat colon. Clinical and experimental pharmacology & physiology 20040701
Stimulation of distal airspace fluid clearance in guinea pigs involves bumetanide-sensitive ion transport. American journal of obstetrics and gynecology 20040701
Ion transport in rabbit caecum at 12 and 36 months of age. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20040701
Cl- uptake promoting depolarizing GABA actions in immature rat neocortical neurones is mediated by NKCC1. The Journal of physiology 20040615
Differential Cl- and HCO3- mediated anion secretion by different colonic cell types in response to tetromethylpyrazine. World journal of gastroenterology 20040615
Lateral intercellular space volume as a determinant of CFTR-mediated anion secretion across small intestinal mucosa. American journal of physiology. Gastrointestinal and liver physiology 20040601
Glutamate-induced elevations in intracellular chloride concentration in hippocampal cell cultures derived from EYFP-expressing mice. The European journal of neuroscience 20040601
Permissive role of nitric oxide in macula densa control of renin secretion. American journal of physiology. Renal physiology 20040501
Cellular potassium ion deprivation enhances apoptosis induced by cisplatin. Basic & clinical pharmacology & toxicology 20040501
Food: an unrecognized source of loop diuretic resistance. Pharmacotherapy 20040501
Basolateral anion transport mechanisms underlying fluid secretion by mouse, rat and guinea-pig pancreatic ducts. The Journal of physiology 20040415
Restitution of the bullfrog gastric mucosa is dependent on a DIDS-inhibitable pathway not related to HCO3- ion transport. American journal of physiology. Gastrointestinal and liver physiology 20040401
Alpha1-AR-mediated activation of NKCC in rat cardiomyocytes involves ERK-dependent phosphorylation of the cotransporter. American journal of physiology. Heart and circulatory physiology 20040401
Blood pressure regulates the activity and function of the Na-K-2Cl cotransporter in vascular smooth muscle. American journal of physiology. Heart and circulatory physiology 20040401
Mechanisms of K+ transport across basolateral membranes of principal cells in Malpighian tubules of the yellow fever mosquito, Aedes aegypti. The Journal of experimental biology 20040401
ATP release triggered by activation of the Ca2+-activated K+ channel in human airway Calu-3 cells. American journal of respiratory cell and molecular biology 20040301
Interactions of human organic anion transporters with diuretics. The Journal of pharmacology and experimental therapeutics 20040301
Sodium-dependent methotrexate carrier-1 is expressed in rat kidney: cloning and functional characterization. American journal of physiology. Renal physiology 20040301
Membrane potential stabilization in amphibian skeletal muscle fibres in hypertonic solutions. The Journal of physiology 20040301
Investigation into the mechanisms by which nedocromil sodium, frusemide and bumetanide inhibit the histamine-induced itch and flare response in human skin in vivo. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040301
Chloride secretion in a morphologically differentiated human colonic cell line that expresses the epithelial Na+ channel. The Journal of physiology 20040215
Molecular mechanisms of Cl- transport by the renal Na(+)-K(+)-Cl- cotransporter. Identification of an intracellular locus that may form part of a high affinity Cl(-)-binding site. The Journal of biological chemistry 20040213
Effect of ethanol extracts of three Chinese medicinal plants with laxative properties on ion transport of the rat intestinal epithelia. Biological & pharmaceutical bulletin 20040201
Neuron-glial trafficking of NH4+ and K+: separate routes of uptake into glial cells of bee retina. The European journal of neuroscience 20040201
Determination of lisinopril in dosage forms and spiked human plasma through derivatization with 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole (NBD-Cl) followed by spectrophotometry or HPLC with fluorimetric detection. Journal of pharmaceutical and biomedical analysis 20040127
Beta 2-adrenergic regulation of ciliary beat frequency in rat bronchiolar epithelium: potentiation by isosmotic cell shrinkage. The Journal of physiology 20040115
Effects of pH and the presence of micelles on the resolution of diuretics by reversed-phase liquid chromatography. Journal of chromatography. A 20040102
Hyperosmolar solution effects in guinea pig airways. II. Epithelial bioelectric responses to relative changes in osmolarity. The Journal of pharmacology and experimental therapeutics 20040101
In skeletal muscle the relaxation of the resting membrane potential induced by K(+) permeability changes depends on Cl(-) transport. Pflugers Archiv : European journal of physiology 20040101
Toxoplasma gondii: changes of transepithelial ion transport in infected HT29/B6 cell monolayers. Parasitology research 20040101
Ion transport in the intestine of Gobius niger in both isotonic and hypotonic conditions. Journal of experimental zoology. Part A, Comparative experimental biology 20040101
Effect of ethanol extracts of three Chinese medicinal plants with anti-diarrheal properties on ion transport of the rat intestinal epithelia. Journal of pharmacological sciences 20040101
Role of ionic fluxes in the apoptotic cell death of cultured cerebellar granule neurons. Neurochemical research 20040101
Chronic administration of bumetanide upregulates calbindin D28k mRNA and protein abundance in rat distal convoluted tubules. Nephron. Physiology 20040101
Effect of antagonists of adrenergic and cholinergic receptors on ion transport in the isolated rabbit caecum wall. Polish journal of pharmacology 20040101
Magnesium, aging, and the elderly patient. TheScientificWorldJournal 20040101
Loss of KCNJ10 protein expression abolishes endocochlear potential and causes deafness in Pendred syndrome mouse model. BMC medicine 20040101
Detubulation abolishes membrane potential stabilization in amphibian skeletal muscle. Journal of muscle research and cell motility 20040101
Regulatory volume increase in nematocytes isolated from acontia of Aiptasia diaphana (Cnidaria, Anthozoa). Cellular and molecular biology (Noisy-le-Grand, France) 20040101
The role of the blood-brain barrier Na-K-2Cl cotransporter in stroke. Advances in experimental medicine and biology 20040101
Basolateral membrane mechanisms involved in ligustrazine-stimulated anion secretion in rat distal colon. Sheng li xue bao : [Acta physiologica Sinica] 20031225
Exercise-induced changes in plasma composition increase erythrocyte Na+,K+-ATPase, but not Na+-K+-2Cl- cotransporter, activity to stimulate net and unidirectional K+ transport in humans. The Journal of physiology 20031215
Role of Cl- co-transporters in the excitation produced by GABAA receptors in juvenile bovine adrenal chromaffin cells. Journal of neurophysiology 20031201
Bumetanide-induced enlargement of the intercellular space in the stria vascularis critically depends on Na+ transport. Hearing research 20031201
A study of the pharmacodynamic differences between immediate and extended release bumetanide formulations. International journal of pharmaceutics 20031128
Independence of apical Cl-/HCO3- exchange and anion conductance in duodenal HCO3- secretion. American journal of physiology. Gastrointestinal and liver physiology 20031101
Differential regulation of renin and Cox-2 expression in the renal cortex of C57Bl/6 mice. Pflugers Archiv : European journal of physiology 20031101
Transport of Cl- across the plasma membrane during pollen grain germination in tobacco. Biochemistry. Biokhimiia 20031101
Functional characterisation of the active ascorbic acid transport into cerebrospinal fluid using primary cultured choroid plexus cells. Brain research 20031024
KCC2 mediates NH4+ uptake in cultured rat brain neurons. Journal of neurophysiology 20031001
Measurement of rapid changes in cell volume by forward light scattering. Pflugers Archiv : European journal of physiology 20031001
Isoosmotic shrinkage by self-stimulated outward Na-K-Cl cotransport in quail erythrocytes. Pflugers Archiv : European journal of physiology 20031001
Specialized protective role of mucosal glutathione in pigmented rabbit conjunctiva. Investigative ophthalmology & visual science 20031001
cAMP inhibition of murine intestinal Na/H exchange requires CFTR-mediated cell shrinkage of villus epithelium. Gastroenterology 20031001
Investigation of the photochemical properties and in vitro phototoxic potential of bumetanide. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20031001
Cl- channels in basolateral TAL membranes. XIX. Cytosolic Cl- regulates mmCIC-Ka and mcCIC-Ka channels. The Journal of membrane biology 20030915
Reciprocal interactions between calcium and chloride in rod photoreceptors. Journal of neurophysiology 20030901
Vasopressin-independent renal urinary concentration: increased rBSC1 and enhanced countercurrent multiplication. Kidney international 20030901
Bumetanide, the specific inhibitor of Na+-K+-2Cl- cotransport, inhibits 1alpha,25-dihydroxyvitamin D3-induced osteoclastogenesis in a mouse co-culture system. Experimental physiology 20030901
Oxygen consumption and chloride secretion in rat distal colon isolated mucosa. Digestive diseases and sciences 20030901
Deafness disrupts chloride transporter function and inhibitory synaptic transmission. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030820
Bicarbonate-dependent chloride secretion in Calu-3 epithelia in response to 7,8-benzoquinoline. The Journal of physiology 20030815
Effects of endothelin-1 on epithelial ion transport in human airways. American journal of respiratory cell and molecular biology 20030801
Effect of Na+,K+,2Cl- cotransport inhibitor bumetanide on electrical and contractile activity of smooth muscle cells in guinea pig ureter. Bulletin of experimental biology and medicine 20030801
Anion-dependent Mg2+ influx and a role for a vacuolar H+-ATPase in sheep ruminal epithelial cells. American journal of physiology. Gastrointestinal and liver physiology 20030701
Disruptive effects of anion secretion inhibitors on airway mucus morphology in isolated perfused pig lung. The Journal of physiology 20030615
Na-K-Cl cotransporter contributes to glutamate-mediated excitotoxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030615
Contribution of chloride channels to volume regulation of cortical astrocytes. American journal of physiology. Cell physiology 20030601
Mutations in the human Na-K-2Cl cotransporter (NKCC2) identified in Bartter syndrome type I consistently result in nonfunctional transporters. Journal of the American Society of Nephrology : JASN 20030601
Effect of the location of hydrogen abstraction on the fragmentation of diuretics in negative electrospray ionization mass spectrometry. Journal of the American Society for Mass Spectrometry 20030601
Aldosterone regulates the Na-K-2Cl cotransporter in vascular smooth muscle. Hypertension (Dallas, Tex. : 1979) 20030501
Secretion of acid and base equivalents by intact distal airways. American journal of physiology. Lung cellular and molecular physiology 20030501
Analysis of energy metabolism and mechanism of loop diuretics in the thick ascending limb of Henle's loop in dog kidneys. Acta physiologica Scandinavica 20030501
Isoprenaline-stimulated differential adrenergic response of K+ channels in skeletal muscle under hypokalaemic conditions. Pflugers Archiv : European journal of physiology 20030501
Membrane ion transport in erythrocytes of salt hypertensive Dahl rats and their F2 hybrids: the importance of cholesterol. Hypertension research : official journal of the Japanese Society of Hypertension 20030501
Only weak vasorelaxant properties of loop diuretics in isolated resistance arteries from man, rat and guinea pig. European journal of pharmacology 20030418
Identification of a functionally important conformation-sensitive region of the secretory Na+-K+-2Cl- cotransporter (NKCC1). The Journal of biological chemistry 20030404
Preserved macula densa-dependent renin secretion in A1 adenosine receptor knockout mice. American journal of physiology. Renal physiology 20030401
Regulation of mastoparan-induced increase of paracellular permeability in T84 cells by RhoA and basolateral potassium channels. Biochemical pharmacology 20030401
K(+) transport in Malpighian tubules of Tenebrio molitor L: a study of electrochemical gradients and basal K(+) uptake mechanisms. The Journal of experimental biology 20030301
Effects of ion transport and channel-blocking drugs on aqueous humor formation in isolated bovine eye. Investigative ophthalmology & visual science 20030301
Saliva secretion and ionic composition of saliva in the cockroach Periplaneta americana after serotonin and dopamine stimulation, and effects of ouabain and bumetamide. Journal of insect physiology 20030301
Furosemide challenge in patients with heart failure and adverse reactions to sulfa-containing diuretics. Annals of internal medicine 20030218
Stability of actin cytoskeleton and PKC-delta binding to actin regulate NKCC1 function in airway epithelial cells. American journal of physiology. Cell physiology 20030201
Characterization and identification of steroid sulfate transporters of human placenta. American journal of physiology. Endocrinology and metabolism 20030201
Localization and characterization of phenamil-sensitive Na+ influx in isolated rainbow trout gill epithelial cells. The Journal of experimental biology 20030201
Asphyxia and diuretic-induced changes in the Ca2+ concentration of endolymph. The Japanese journal of physiology 20030201
Inhibition of Na(+)-K(+)-Cl(-) cotransporter during focal cerebral ischemia decreases edema and neuronal damage. Brain research 20030124
Dose-effect relations of loop- and thiazide-diuretics on calcium homeostasis: a randomized, double-blinded Latin-square multiple cross-over study in postmenopausal osteopenic women. European journal of clinical investigation 20030101
Beta-adrenergic stimulation of Na(+)-K(+)-2Cl(-) cotransport activity in the rabbit lens. Experimental eye research 20030101
Pharmacokinetic changes during extracorporeal membrane oxygenation: implications for drug therapy of neonates. Clinical pharmacokinetics 20030101
Endolymphatic sodium homeostasis by Reissner's membrane. Neuroscience 20030101
Effects of amiloride and bumetanide on ion transport in the caecum of rabbit. Polish journal of pharmacology 20030101
Effect of amiloride and bumetanide on ionic currents in the epithelium of caecum from starved rabbits. Polish journal of pharmacology 20030101
Effect of curing conditions and plasticizer level on the release of highly lipophilic drug from coated multiparticulate drug delivery system. Pharmaceutical development and technology 20030101
Effect of phenazine methosulphate on K+ transport in human red cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20030101
Effect of capsaicin and dimethyl sulphoxide (DMSO) on ion transport in isolated skin of frog (Rana esculenta L.). Folia biologica 20030101
Pharmacological suppression of rat distal colon chloride secretion requires two blockers. Acta gastroenterologica Latinoamericana 20030101
Regulation of Na(+)-K(+)-2Cl- cotransporter activity in rat skeletal muscle and intestinal epithelial cells. Tsitologiia 20030101
Allopregnanolone enhancement of GABAergic transmission in rat medial preoptic area neurons. American journal of physiology. Endocrinology and metabolism 20021201
Fluvastatin-induced rhabdomyolysis. The Annals of pharmacotherapy 20021201
Screening for 18 diuretics and probenecid in doping analysis by liquid chromatography-tandem mass spectrometry. Biomedical chromatography : BMC 20021201
Forskolin-induced clearance of the fluorescent dye sulforhodamine from rat parotid intralobular duct lumen: visualization of the secretory function under a confocal laser scanning microscope. The Journal of membrane biology 20021201
Bumetanide-induced enlargement of the intercellular space in the stria vascularis requires an active Na+-K+-ATPase. Acta oto-laryngologica 20021201
Osmotic shrinkage of human cervical cancer cells induces an extracellular Cl- -dependent nonselective cation channel, which requires p38 MAPK. The Journal of biological chemistry 20021129
Excitation- and beta(2)-agonist-induced activation of the Na(+)-K(+) pump in rat soleus muscle. The Journal of physiology 20021115
Decreased blood pressure and vascular smooth muscle tone in mice lacking basolateral Na(+)-K(+)-2Cl(-) cotransporter. American journal of physiology. Heart and circulatory physiology 20021101
Calcium-stimulated short-circuit currents in the canine proximal colonic epithelium: effects of DK-PGD2, a metabolite of prostaglandin D2. Canadian journal of physiology and pharmacology 20021101
Rehydration of high-density sickle erythrocytes in vitro. Blood 20021015
Functional and molecular evidence for Na(+)-HCO cotransporter in porcine vas deferens epithelia. American journal of physiology. Cell physiology 20021001
Coiled body heterogeneity induced by G(1) arrest with amiloride + bumetanide. Experimental cell research 20020910
Calcium-sensing receptor regulation of PTH-dependent calcium absorption by mouse cortical ascending limbs. American journal of physiology. Renal physiology 20020901
Carbachol-induced fluid movement through methazolamide-sensitive bicarbonate production in rat parotid intralobular ducts: quantitative analysis of fluorescence images using fluorescent dye sulforhodamine under a confocal laser scanning microscope. European journal of cell biology 20020901
Mucus secretion from single submucosal glands of pig. Stimulation by carbachol and vasoactive intestinal peptide. The Journal of biological chemistry 20020802
Liquid secretion inhibitors reduce mucociliary transport in glandular airways. American journal of physiology. Lung cellular and molecular physiology 20020801
Role of luminal ATP in regulating electrogenic Na(+) absorption in guinea pig distal colon. American journal of physiology. Gastrointestinal and liver physiology 20020801
An alternate pathway of cAMP-stimulated Cl secretion across the NKCC1-null murine duodenum. Gastroenterology 20020801
Electrogenic ion transport in the intestine of the Australian common brushtail possum, Trichosurus vulpecula: indications of novel transport patterns in a marsupial. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20020801
The effects of drugs modulating K(+) transport on Rb(+) uptake and distribution in pig hearts following regional ischemia: (87)Rb MRI study. NMR in biomedicine 20020801
Disparity between ionic mediators of volume regulation and apoptosis in N1E 115 mouse neuroblastoma cells. Brain research 20020712
Human trabecular meshwork cell volume regulation. American journal of physiology. Cell physiology 20020701
Effects of chloride transport on bistable behaviour of the membrane potential in mouse skeletal muscle. The Journal of physiology 20020701
In vitro anion transport alterations and apoptosis induced by phenylbutazone in the right dorsal colon of ponies. American journal of veterinary research 20020701
Methoxsalen stimulates electrogenic Cl- secretion in the mouse jejunum. Experimental physiology 20020701
Intracellular ion activities in Malpighian tubule cells of Rhodnius prolixus: evaluation of Na+-K+-2Cl- cotransport across the basolateral membrane. The Journal of experimental biology 20020601
Involvement of Na+-HCO3- cotransporter in mediating cyclic adenosine 3',5'-monophosphate-dependent HCO3- secretion by mouse endometrial epithelium. Biology of reproduction 20020601
Inhibitors of NHE-1 Na+/H+ exchange reduce mouse intraocular pressure. Investigative ophthalmology & visual science 20020601
Reduction of KCC2 expression and GABAA receptor-mediated excitation after in vivo axonal injury. The Journal of neuroscience : the official journal of the Society for Neuroscience 20020601
Effect of ambroxol on ion transport -- a model study. Medical science monitor : international medical journal of experimental and clinical research 20020601
Intrinsic optical signals in the dorsal horn of rat spinal cord slices elicited by brief repetitive stimulation. The European journal of neuroscience 20020601
Expression and regulation of the Na(+)/K(+)/2Cl(-) cotransporter NKCC1 in rat liver and human HuH-7 hepatoma cells. Archives of biochemistry and biophysics 20020515
Contribution of Na(+)-K(+)-Cl(-) cotransporter to high-[K(+)](o)- induced swelling and EAA release in astrocytes. American journal of physiology. Cell physiology 20020501
Astrocytes from Na(+)-K(+)-Cl(-) cotransporter-null mice exhibit absence of swelling and decrease in EAA release. American journal of physiology. Cell physiology 20020501
Modulation of Na-K-2Cl cotransport by intracellular Cl(-) and protein kinase C-delta in Calu-3 cells. American journal of physiology. Lung cellular and molecular physiology 20020501
Model study of toluene diisocyanate effect on transepithelial ion transport. Medical science monitor : international medical journal of experimental and clinical research 20020501
Effect of hydrochloric acid, pepsin, or taurocholate on bioelectric properties of gastric squamous mucosa in horses. American journal of veterinary research 20020501
Risk factors for the development and progression of dyslipidemia after heart transplantation. Transplantation 20020427
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. The Journal of biological chemistry 20020419
cAMP regulation of Cl(-) and HCO(-)(3) secretion across rat fetal distal lung epithelial cells. American journal of physiology. Lung cellular and molecular physiology 20020401
Manipulation of chloride flux affects histamine-induced contraction in rabbit basilar artery. American journal of physiology. Heart and circulatory physiology 20020401
Chloride transport in rabbit esophageal epithelial cells. American journal of physiology. Gastrointestinal and liver physiology 20020401
Steroids modulate transepithelial resistance and Na(+) absorption across cultured porcine vas deferens epithelia. Biology of reproduction 20020401
NKCC2: a drug target in hypertension. Journal of hypertension 20020401
Renal Na-K-Cl cotransporter NKCC2 in Dahl salt-sensitive rats. Journal of hypertension 20020401
Contribution of the Na(+)-K(+)-2Cl(-) cotransporter (NKCC1) to transepithelial transport of H(+), NH(4)(+), K(+), and Na(+) in rat outer medullary collecting duct. Journal of the American Society of Nephrology : JASN 20020401
Purinergic-induced ion current in monolayers of C7-MDCK cells: role of basolateral and apical ion transporters. The Journal of membrane biology 20020401
Functional properties of the apical Na+-K+-2Cl- cotransporter isoforms. The Journal of biological chemistry 20020329
Fast screening method for the determination of angiotensin II receptor antagonists in human plasma by high-performance liquid chromatography with fluorimetric detection. Journal of chromatography. A 20020308
The flavonol quercetin activates basolateral K(+) channels in rat distal colon epithelium. British journal of pharmacology 20020301
Rat NKCC2/NKCC1 cotransporter selectivity for loop diuretic drugs. Naunyn-Schmiedeberg's archives of pharmacology 20020301
Effects of butyrate on active sodium and chloride transport in rat and rabbit distal colon. The Journal of physiology 20020215
Basolateral PAR-2 receptors mediate KCl secretion and inhibition of Na+ absorption in the mouse distal colon. The Journal of physiology 20020215
Tonic and spillover inhibition of granule cells control information flow through cerebellar cortex. Neuron 20020214
Activation of NKCC1 by hyperosmotic stress in human tracheal epithelial cells involves PKC-delta and ERK. Biochimica et biophysica acta 20020213
Intrinsic optical signals in the rat optic nerve: role for K(+) uptake via NKCC1 and swelling of astrocytes. Glia 20020201
Interleukin-13 induces a hypersecretory ion transport phenotype in human bronchial epithelial cells. American journal of physiology. Lung cellular and molecular physiology 20020201
Activation of ion secretion via proteinase-activated receptor-2 in human colon. American journal of physiology. Gastrointestinal and liver physiology 20020201
Na(+)/K(+)/Cl(-) cotransporter activates mitogen-activated protein kinase in fibroblasts and lymphocytes. Journal of cellular physiology 20020201
Cellular signaling mechanisms underlying pharmacological action of Bak Foong Pills on gastrointestinal secretion. The Japanese journal of physiology 20020201
Cyclic AMP-dependent Cl secretion is regulated by multiple phosphodiesterase subtypes in human colonic epithelial cells. The Journal of membrane biology 20020115
Roles of the cytoskeleton and of protein phosphorylation events in the osmotic stress response in eel intestinal epithelium. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20020101
Correction for the adverse influence of sodium-potassium cotransport on apparent sodium-lithium countertransport activity in human erythrocytes. Journal of pharmacological and toxicological methods 20020101
Effect of capsaicin and dimethyl sulfoxide on ion transport in the selected experimental models. Polish journal of pharmacology 20020101
K(+) transport and volume regulatory response by NKCC in resting rat hindlimb skeletal muscle. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20020101
Transport of anionic drugs across the basolateral membrane of proximal S2 segments of the rabbit kidney. Inverse relationship between the affinity to the p-aminohippurate transport system and the transport rate. Arzneimittel-Forschung 20020101
Effect of capsaicin on ion transport in the caecum of rabbits. Polish journal of pharmacology 20020101
[Potassium transport in erythrocytes from patients with gentamicin intolerance]. Tsitologiia 20020101
Transepithelial transport of sodium and chloride ions in isolated skin of the frog, Rana esculenta L. Folia biologica 20020101
Growth factors stimulate the Na-K-2Cl cotransporter NKCC1 through a novel Cl(-)-dependent mechanism. American journal of physiology. Cell physiology 20011201
Bumetanide annihilation of amphotericin B-induced apoptosis and cytotoxicity is due to its effect on cellular K+ flux. The Journal of antimicrobial chemotherapy 20011201
Neurotransmitter-stimulated ion transport across cultured bovine mammary epithelial cell monolayers. Journal of dairy science 20011201
An integrative, in situ approach to examining K+ flux in resting skeletal muscle. Canadian journal of physiology and pharmacology 20011201
Vacuolation induced by VacA toxin of Helicobacter pylori requires the intracellular accumulation of membrane permeant bases, Cl(-) and water. FEBS letters 20011123
Role of Cl- current in endothelin-1-induced contraction in rabbit basilar artery. American journal of physiology. Heart and circulatory physiology 20011101
Localization of a Na(+)-K(+)-2Cl(-) cotransporter in the rabbit lens. Experimental eye research 20011101
Selective inhibition of Cl(-) conductance in toad skin by blockers of Cl(-) channels and transporters. American journal of physiology. Cell physiology 20011001
Prostanoids stimulate K secretion and Cl secretion in guinea pig distal colon via distinct pathways. American journal of physiology. Gastrointestinal and liver physiology 20011001
Ion transport by sheep distal airways in a miniature chamber. American journal of physiology. Lung cellular and molecular physiology 20011001
Indirectly gated Cl(-)-dependent Cl(-) channels sense physiological changes of extracellular chloride in the leech. Journal of neurophysiology 20011001
Quantitative determination of the loop diuretic bumetanide in urine and pharmaceuticals by high-performance liquid chromatography with amperometric detection. Journal of chromatographic science 20011001
Mechanism(s) of chloride transport in human distal colonic apical membrane vesicles. Digestive diseases and sciences 20011001
Ionic mechanisms of GABA-induced long-term potentiation in the rat superior colliculus. Experimental brain research 20011001
Ion transport and ligand binding by the Na-K-Cl cotransporter, structure-function studies. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20011001
Mechanism of substance P-induced liquid secretion across bronchial epithelium. American journal of physiology. Lung cellular and molecular physiology 20010901
Spontaneous water secretion in T84 cells: effects of STa enterotoxin, bumetanide, VIP, forskolin, and A-23187. American journal of physiology. Gastrointestinal and liver physiology 20010901
Apoptosis in post-streptococcal glomerulonephritis. Kidney international 20010901
Thermogenesis induced by intravenous infusion of hypertonic solutions in the rat. The Journal of physiology 20010901
Loop diuretics alter the diurnal rhythm of endogenous parathyroid hormone secretion. A randomized-controlled study on the effects of loop- and thiazide-diuretics on the diurnal rhythms of calcitropic hormones and biochemical bone markers in postmenopausal women. European journal of clinical investigation 20010901
Potentiation of urinary atrial natriuretic peptide interferes with macula densa function. Cardiovascular research 20010815
Cisplatin-induced apoptosis of mesothelioma cells is affected by potassium ion flux modulator amphotericin B and bumetanide. International journal of cancer 20010815
Contribution of the Na-K-Cl cotransporter on GABA(A) receptor-mediated presynaptic depolarization in excitatory nerve terminals. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010815
Optical method for quantifying rates of mucus secretion from single submucosal glands. American journal of physiology. Lung cellular and molecular physiology 20010801
Contractile regulation of the Na(+)-K(+)-2Cl(-) cotransporter in vascular smooth muscle. American journal of physiology. Cell physiology 20010801
Alterations in airway ion transport in NKCC1-deficient mice. American journal of physiology. Cell physiology 20010801
Functional and molecular characterization of the K-Cl cotransporter of Xenopus laevis oocytes. American journal of physiology. Cell physiology 20010801
Cl(-)-dependent secretory mechanisms in isolated rat bile duct epithelial units. American journal of physiology. Gastrointestinal and liver physiology 20010801
Insulin-independent, MAPK-dependent stimulation of NKCC activity in skeletal muscle. American journal of physiology. Regulatory, integrative and comparative physiology 20010801
Protection of ischemic myocardium in diabetics by inhibition of electroneutral Na+-K+-2Cl- cotransporter. American journal of physiology. Heart and circulatory physiology 20010801
'Avian-type' renal medullary tubule organization causes immaturity of urine-concentrating ability in neonates. Kidney international 20010801
Loop diuretics and in vitro relaxation of human fetal and newborn mouse airways. Pediatric research 20010801
Effects of thiazide- and loop-diuretics, alone or in combination, on calcitropic hormones and biochemical bone markers: a randomized controlled study. Journal of internal medicine 20010801
Differential roles of the sodium-calcium exchanger in renin secretion and renal vascular resistance. Pflugers Archiv : European journal of physiology 20010801
Regional differences in ciliary epithelial cell transport properties. The Journal of membrane biology 20010801
Forskolin activation of apical Cl- channel and Na+/K+/2Cl- cotransporter via a PTK-dependent pathway in renal epithelium. Biochemical and biophysical research communications 20010727
Epinephrine-induced increases in [Ca2+](in) and KCl-coupled fluid absorption in bovine RPE. Investigative ophthalmology & visual science 20010701
Effects of the potassium channel blocker barium on sodium and potassium transport in the rat loop of Henle in vivo. Experimental physiology 20010701
Liquid and ion transport by fetal airway and lung epithelia of mice deficient in sodium-potassium-2-chloride transporter. American journal of respiratory cell and molecular biology 20010701
HCO3- transport in relation to mucus secretion from submucosal glands. JOP : Journal of the pancreas 20010701
Application of multiple response optimization technique to extended release formulations design. Journal of controlled release : official journal of the Controlled Release Society 20010615
K(+) transport in red blood cells from human umbilical cord. Biochimica et biophysica acta 20010606
Endogenous and exogenous Na-K-Cl cotransporter expression in a low K-resistant mutant MDCK cell line. American journal of physiology. Cell physiology 20010601
cAMP-dependent fluid secretion in rat inner medullary collecting ducts. American journal of physiology. Renal physiology 20010601
Determination and characterization of diuretics in human urine by liquid chromatography coupled to pneumatically assisted electrospray ionization mass spectrometry. Journal of mass spectrometry : JMS 20010601
Two further British families with the 'cryohydrocytosis' form of hereditary stomatocytosis. British journal of haematology 20010601
Na+-K+-Cl- cotransporter in rat focal cerebral ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20010601
Ethanol-induced swelling in neonatal rat primary astrocyte cultures. Brain research 20010511
Contribution of the Na+-K+-2Cl- cotransporter NKCC1 to Cl- secretion in rat OMCD. American journal of physiology. Renal physiology 20010501
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney. Molecular pharmacology 20010501
Role of renocortical cyclooxygenase-2 for renal vascular resistance and macula densa control of renin secretion. Journal of the American Society of Nephrology : JASN 20010501
Pulmonary oedema after ophthalmic regional anaesthesia in an unfasted patient undergoing elective surgery. Anaesthesia 20010501
Diverging effects of 5-HT3 receptor antagonists ondansetron and granisetron on estramustine-inhibited cellular potassium transport. Pharmacology & toxicology 20010501
HCO3- potentiates the cAMP-dependent secretory response of the human distal colon through a DIDS-sensitive pathway. Pflugers Archiv : European journal of physiology 20010501
Pharmacokinetics and pharmacodynamics of intravenous bumetanide in mutant Nagase analbuminemic rats: importance of globulin binding for the pharmacodynamic effects. Biopharmaceutics & drug disposition 20010501
Insulin increases the turnover rate of Na+-K+-ATPase in human fibroblasts. American journal of physiology. Cell physiology 20010401
Alternatively spliced isoform of apical Na(+)-K(+)-Cl(-) cotransporter gene encodes a furosemide-sensitive Na(+)-Cl(-)cotransporter. American journal of physiology. Renal physiology 20010401
Effect of chloride channel blockers on anti-IgE-stimulated histamine and IL-4/IL-13 release from human basophils. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20010401
Corneal endothelial NKCC: molecular identification, location, and contribution to fluid transport. American journal of physiology. Cell physiology 20010301
Serotonin-elicited inhibition of Cl(-) secretion in the rabbit conjunctival epithelium. American journal of physiology. Cell physiology 20010301
Ion transport and regulation of respiratory tract fluid output in dogs. Journal of applied physiology (Bethesda, Md. : 1985) 20010301
Inhibition of Na(+)/K(+)-atpase by endothelin-1 in human nonpigmented ciliary epithelial cells. The Journal of pharmacology and experimental therapeutics 20010301
Na+ reabsorption in cultured rat epididymal epithelium via the Na+/nucleoside cotransporter. Biology of reproduction 20010301
Optical imaging reveals cation--Cl(-) cotransporter-mediated transient rapid decrease in intracellular Cl(-) concentration induced by oxygen--glucose deprivation in rat neocortical slices. Neuroscience research 20010301
Gramicidin-perforated patch analysis on HCO3- secretion through a forskolin-activated anion channel in rat parotid intralobular duct cells. The Journal of membrane biology 20010301
Ca++ regulation of paracellular permeability in the middle intestine of the eel, Anguilla anguilla. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20010301
Activation of Na(+), K(+), Cl(-)-cotransport mediates intracellular Ca(2+) increase and apoptosis induced by Pinacidil in HepG2 human hepatoblastoma cells. Biochemical and biophysical research communications 20010223
Reduced Na-K pump but increased Na-K-2Cl cotransporter in aorta of streptozotocin-induced diabetic rat. American journal of physiology. Heart and circulatory physiology 20010201
Effects of isoprostanes and prostanoids on porcine small intestine. The Journal of pharmacology and experimental therapeutics 20010201
Effect of short-term treatment with bumetanide, quinapril and low-sodium diet on dogs with moderate congestive heart failure. Australian veterinary journal 20010201
The effect of serotonin on airway transepithelial sodium ion pathways. European journal of pharmacology 20010126
Hepatic uptake of synthetic chlorogenic acid derivatives by the organic anion transport proteins. The Journal of pharmacology and experimental therapeutics 20010101
Adrenergic receptor activated ion transport in human fetal retinal pigment epithelium. Investigative ophthalmology & visual science 20010101
Vasopressin regulates water flow in a rat cortical collecting duct cell line not containing known aquaporins. The Journal of membrane biology 20010101
Na(+)-dependent fluid absorption in intact perfused rat colonic crypts. Gastroenterology 20010101
Hypertonicity stimulates Cl(-) transport in the intestine of fresh water acclimated eel, Anguilla anguilla. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20010101
Solubilization and stability of bumetanide in vehicles for intranasal administration, a pilot study. Pharmaceutical development and technology 20010101
Diuretic therapy and resistance in congestive heart failure. Cardiology 20010101
External Cl(-)-dependent formation of watery vacuoles by long-term hypotonic shock in 3T3-L1 cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20010101
[Model experiments of physiologic and pharmacologic interactions with epithelial ionic currents induced by stimulation of sensory receptors ]. Annales Academiae Medicae Stetinensis 20010101
Functional comparison of the K+-Cl- cotransporters KCC1 and KCC4. The Journal of biological chemistry 20000929
Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta. The Journal of biological chemistry 20000211
Endothelial cell shrinkage increases permeability through a Ca2+-dependent pathway in single frog mesenteric microvessels. The Journal of physiology 19990701
Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain. The Journal of biological chemistry 19990507
Pharmacokinetics and pharmacodynamics of bumetanide in critically ill pediatric patients. Journal of clinical pharmacology 19981101
The regulation of Na/K/2Cl cotransport and bumetanide binding in avian erythrocytes by protein phosphorylation and dephosphorylation. Effects of kinase inhibitors and okadaic acid. The Journal of biological chemistry 19901205
[Bumetanide as replacement therapy in furosemide-induced vasculitis]. Presse medicale (Paris, France : 1983) 19901006
Nifedipine and prostatism. The Journal of the Royal College of General Practitioners 19880101
Severe musculoskeletal syndrome in patients with renal failure and hypoalbuminemia receiving bumetanide. Clinical pharmacy 19870901
Quantitative evaluation of ototoxic side effects of furosemide, piretanide, bumetanide, azosemide and ozolinone in the cat--a new approach to the problem of ototoxicity. Naunyn-Schmiedeberg's archives of pharmacology 19851101
Effects of prostaglandins inhibition on changes in active and inactive renin induced by antihypertensive drugs. Clinical and experimental hypertension. Part A, Theory and practice 19820101
Emergency treatment of high blood pressure with oral atenolol. British medical journal (Clinical research ed.) 19810704
Obstructive jaundice, pancytophenia and hydralazine. Lancet (London, England) 19810530
Effect of probenecid on the natriuresis and renin release induced by bumetanide in man. Journal of clinical pharmacology 19810101
Letter: Frusemide, bumetanide, and ototoxicity. Lancet (London, England) 19760424
Diuretic action of bumetanide in advanced chronic renal insufficiency. European journal of clinical pharmacology 19760206
Bumetanide in congestive heart failure. Current medical research and opinion 19760101
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