4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one
Title | Journal |
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Aristolochic acid I interferes with the expression of BLCAP tumor suppressor gene in human cells. | Toxicology letters 20180701 |
Multiple drug transporters mediate the placental transport of sulpiride. | Archives of toxicology 20171201 |
Self-assembled 3D spheroids and hollow-fibre bioreactors improve MSC-derived hepatocyte-like cell maturation in vitro. | Archives of toxicology 20170401 |
Pyruvate Dehydrogenase Kinase 4 Deficiency Results in Expedited Cellular Proliferation through E2F1-Mediated Increase of Cyclins. | Molecular pharmacology 20170301 |
Oxidative stress-induced epigenetic changes associated with malignant transformation of human kidney epithelial cells. | Oncotarget 20170214 |
Determinants of orofacial clefting I: Effects of 5-Aza-2'-deoxycytidine on cellular processes and gene expression during development of the first branchial arch. | Reproductive toxicology (Elmsford, N.Y.) 20170101 |
Determinants of orofacial clefting II: Effects of 5-Aza-2'-deoxycytidine on gene methylation during development of the first branchial arch. | Reproductive toxicology (Elmsford, N.Y.) 20170101 |
Long-term exposure to estrogen enhances chemotherapeutic efficacy potentially through epigenetic mechanism in human breast cancer cells. | PloS one 20170101 |
Role of the antioxidant defence system and telomerase in arsenic-induced genomic instability. | Mutagenesis 20161101 |
Nephrotoxicity of epigenetic inhibitors used for the treatment of cancer. | Chemico-biological interactions 20161025 |
DNA methylome changes by estradiol benzoate and bisphenol A links early-life environmental exposures to prostate cancer risk. | Epigenetics 20160901 |
Cotreatment with Smac mimetics and demethylating agents induces both apoptotic and necroptotic cell death pathways in acute lymphoblastic leukemia cells. | Cancer letters 20160528 |
Epigenetic Modulators and the New Immunotherapies. | The New England journal of medicine 20160218 |
Zebrafish embryos as a screen for DNA methylation modifications after compound exposure. | Toxicology and applied pharmacology 20160115 |
Function of DNA methyltransferase 3a in lead (Pb(2+) )-Induced Cyclooxygenase-2 gene. | Environmental toxicology 20150901 |
Azacytidine sensitizes acute myeloid leukemia cells to arsenic trioxide by up-regulating the arsenic transporter aquaglyceroporin 9. | Journal of hematology & oncology 20150101 |
Synergism of arsenic trioxide and MG132 in Raji cells attained by targeting BNIP3, autophagy, and mitochondria with low doses of valproic acid and vincristine. | European journal of cancer (Oxford, England : 1990) 20141201 |
Arsenic induces polyadenylation of canonical histone mRNA by down-regulating stem-loop-binding protein gene expression. | The Journal of biological chemistry 20141114 |
Epigenetic changes in p21 expression in renal cells after exposure to bromate. | Toxicological sciences : an official journal of the Society of Toxicology 20141001 |
Downregulation of glutathione S-transferase M1 protein in N-butyl-N-(4-hydroxybutyl)nitrosamine-induced mouse bladder carcinogenesis. | Toxicology and applied pharmacology 20140915 |
DNMT3A silencing RASSF1A promotes cardiac fibrosis through upregulation of ERK1/2. | Toxicology 20140902 |
Long-term low-dose exposure of human urothelial cells to sodium arsenite activates lipocalin-2 via promoter hypomethylation. | Archives of toxicology 20140801 |
Epigenetic determinants of CYP1A1 induction by the aryl hydrocarbon receptor agonist 3,3',4,4',5-pentachlorobiphenyl (PCB 126). | International journal of molecular sciences 20140801 |
Silencing of the DNA mismatch repair gene MLH1 induced by hypoxic stress in a pathway dependent on the histone demethylase LSD1. | Cell reports 20140724 |
The acquisition of cancer stem cell-like properties and neoplastic transformation of human keratinocytes induced by arsenite involves epigenetic silencing of let-7c via Ras/NF-κB. | Toxicology letters 20140605 |
Epigenetic silencing of Na,K-ATPase β 1 subunit gene ATP1B1 by methylation in clear cell renal cell carcinoma. | Epigenetics 20140401 |
[Effect of arsenic trioxide and 5-aza-2'-deoxycytidine on SHP-1, JAK3, TYK2 gene expression in K562 cells]. | Zhongguo shi yan xue ye xue za zhi 20140401 |
SOCS1 hypermethylation mediated by DNMT1 is associated with lipopolysaccharide-induced inflammatory cytokines in macrophages. | Toxicology letters 20140321 |
Methylation and miRNA effects of resveratrol on mammary tumors vs. normal tissue. | Nutrition and cancer 20140101 |
Epigenetic regulation of sox30 is associated with testis development in mice. | PloS one 20140101 |
5,6-Dihydro-5-aza-2'-deoxycytidine potentiates the anti-HIV-1 activity of ribonucleotide reductase inhibitors. | Bioorganic & medicinal chemistry 20131115 |
Changes in DNA methylation of erythroid-specific genes in K562 cells exposed to phenol and hydroquinone. | Toxicology 20131004 |
Inhibition of DNA methylation attenuates low-dose cadmium-induced cardiac contractile and intracellular Ca(2+) anomalies. | Clinical and experimental pharmacology & physiology 20131001 |
Smac mimetic and demethylating agents synergistically trigger cell death in acute myeloid leukemia cells and overcome apoptosis resistance by inducing necroptosis. | Cell death & disease 20130901 |
Laccaic acid A is a direct, DNA-competitive inhibitor of DNA methyltransferase 1. | The Journal of biological chemistry 20130816 |
Identification of potent Yes1 kinase inhibitors using a library screening approach. | Bioorganic & medicinal chemistry letters 20130801 |
5-Azacytidine induces early stage apoptosis and promotes in vitro maturation by changing chromosomal construction in murine oocytes. | Reproductive toxicology (Elmsford, N.Y.) 20130601 |
5-Aza-2'-deoxycytidine inhibited PDGF-induced rat airway smooth muscle cell phenotypic switching. | Archives of toxicology 20130501 |
A DNA methyltransferase inhibitor, 5-aza-2'-deoxycytidine, exacerbates neurotoxicity and upregulates Parkinson's disease-related genes in dopaminergic neurons. | CNS neuroscience & therapeutics 20130301 |
Epigenetic therapies in MDS and AML. | Advances in experimental medicine and biology 20130101 |
Lactate dehydrogenase-B is silenced by promoter methylation in a high frequency of human breast cancers. | PloS one 20130101 |
Efficacy of RNA polymerase II inhibitors in targeting dormant leukaemia cells. | BMC pharmacology & toxicology 20130101 |
Increased PRAME-specific CTL killing of acute myeloid leukemia cells by either a novel histone deacetylase inhibitor chidamide alone or combined treatment with decitabine. | PloS one 20130101 |
5-aza-CdR induces the demethylation of Syk promoter in nasopharyngeal carcinoma cell. | Gene 20121215 |
Screening of drugs to counteract human papillomavirus 16 E6 repression of E-cadherin expression. | Investigational new drugs 20121201 |
Activation of silenced tumor suppressor genes in prostate cancer cells by a novel energy restriction-mimetic agent. | The Prostate 20121201 |
Hypoxia-inducible factor-1α expression indicates poor prognosis in myelodysplastic syndromes. | Leukemia & lymphoma 20121201 |
Gemcitabine reactivates epigenetically silenced genes and functions as a DNA methyltransferase inhibitor. | International journal of molecular medicine 20121201 |
Protocadherin8 is a functional tumor suppressor frequently inactivated by promoter methylation in nasopharyngeal carcinoma. | European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20121101 |
Refractory anemia with ring sideroblasts associated with marked thrombocytosis harboring cytogenetic abnormality dup(2)(p15p22) treated with decitabine. | Leukemia & lymphoma 20121101 |
Antineoplastic activity of the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine in anaplastic large cell lymphoma. | Biochimie 20121101 |
Methylome analysis and integrative profiling of human HCCs identify novel protumorigenic factors. | Hepatology (Baltimore, Md.) 20121101 |
Erythroblastic sarcoma, an extremely rare variant of myeloid sarcoma. | Human pathology 20121101 |
PROX1 overexpression inhibits protein kinase C beta II transcription through promoter DNA methylation. | Genes, chromosomes & cancer 20121101 |
Synergism between clofarabine and decitabine through p53R2: a pharmacodynamic drug-drug interaction modeling. | Leukemia research 20121101 |
Could decitabine treatment impair memory functions in humans? | Medical hypotheses 20121101 |
Epigenetic mechanisms regulate the prostaglandin E receptor 2 in breast cancer. | The Journal of steroid biochemistry and molecular biology 20121101 |
Frequent silencing of protocadherin 8 by promoter methylation, a candidate tumor suppressor for human gastric cancer. | Oncology reports 20121101 |
DNA methyltransferase inhibitors in acute myeloid leukemia: discovery, design and first therapeutic experiences. | Expert opinion on drug discovery 20121101 |
Anti-HIV-1 activity of resveratrol derivatives and synergistic inhibition of HIV-1 by the combination of resveratrol and decitabine. | Bioorganic & medicinal chemistry letters 20121101 |
HTLV infection and the eye. | Current opinion in ophthalmology 20121101 |
Analysis of possible mechanisms accounting for raf-1 kinase inhibitor protein downregulation in hepatocellular carcinoma. | Omics : a journal of integrative biology 20121101 |
Tet2 facilitates the derepression of myeloid target genes during CEBPα-induced transdifferentiation of pre-B cells. | Molecular cell 20121026 |
Methylation subtypes and large-scale epigenetic alterations in gastric cancer. | Science translational medicine 20121017 |
Induced production of mycotoxins in an endophytic fungus from the medicinal plant Datura stramonium L. | Bioorganic & medicinal chemistry letters 20121015 |
DNA methylation of the CYP1A1 enhancer is associated with smoking-induced genetic alterations in human lung. | International journal of cancer 20121001 |
Sequence-specific biosensors report drug-induced changes in epigenetic silencing in living cells. | DNA and cell biology 20121001 |
Ischemic cardiac tissue conditioned media induced differentiation of human mesenchymal stem cells into early stage cardiomyocytes. | Cytotechnology 20121001 |
Over-expression of RPL23 in myelodysplastic syndromes is associated with apoptosis resistance of CD34+ cells and predicts poor prognosis and distinct response to CHG chemotherapy or decitabine. | Annals of hematology 20121001 |
Effects of hepatocyte growth factor overexpressed bone marrow-derived mesenchymal stem cells on prevention from left ventricular remodelling and functional improvement in infarcted rat hearts. | Cell biochemistry and function 20121001 |
Durable complete remission after azacitidine treatment in a patient with erythroleukaemia. | European journal of haematology 20121001 |
Epigenetic modifiers enhance the synergistic cytotoxicity of combined nucleoside analog-DNA alkylating agents in lymphoma cell lines. | Experimental hematology 20121001 |
Comprehensive DNA methylation analysis of benign and malignant adrenocortical tumors. | Genes, chromosomes & cancer 20121001 |
The p16-specific reactivation and inhibition of cell migration through demethylation of CpG islands by engineered transcription factors. | Human gene therapy 20121001 |
Hypermethylation of Wnt antagonist gene promoters and activation of Wnt pathway in myelodysplastic marrow cells. | Leukemia research 20121001 |
Fas expression at diagnosis as a biomarker of azacitidine activity in high-risk MDS and secondary AML. | Leukemia 20121001 |
14-3-3σ mediates G2-M arrest produced by 5-aza-2'-deoxycytidine and possesses a tumor suppressor role in endometrial carcinoma cells. | Gynecologic oncology 20121001 |
Phase I/II study of decitabine in patients with myelodysplastic syndrome: a multi-center study in Japan. | Cancer science 20121001 |
Enforced expression of RASAL1 suppresses cell proliferation and the transformation ability of gastric cancer cells. | Oncology reports 20121001 |
Reexpression of tumor suppressor, sFRP1, leads to antitumor synergy of combined HDAC and methyltransferase inhibitors in chemoresistant cancers. | Molecular cancer therapeutics 20121001 |
DNMT1-mediated PTEN hypermethylation confers hepatic stellate cell activation and liver fibrogenesis in rats. | Toxicology and applied pharmacology 20121001 |
Increased cleavage rate of human nuclear transfer embryos after 5-aza-2'-deoxycytidine treatment. | Reproductive biomedicine online 20121001 |
CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer. | Cancer biology & therapy 20121001 |
Decitabine, a DNA methyltransferase inhibitor, reduces P-glycoprotein mRNA and protein expressions and increases drug sensitivity in drug-resistant MOLT4 and Jurkat cell lines. | Anticancer research 20121001 |
Treatment of advanced myelodysplastic syndrome with demethylating agents: azacitidine. | Seminars in hematology 20121001 |
Clinical results with the DNA hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in patients with myelodysplastic syndromes: an update. | Seminars in hematology 20121001 |
The role of DNA methylation in aging, rejuvenation, and age-related disease. | Rejuvenation research 20121001 |
[Methylation of FHIT gene promoter region in DNA from plasma of patients with myelodysplastic syndromes and demethylating effect of decitabine]. | Zhongguo shi yan xue ye xue za zhi 20121001 |
Epigenetic remodelling of gene expression profiles of neoplastic and normal tissues: immunotherapeutic implications. | British journal of cancer 20120925 |
Genome-wide methylation profiling in decitabine-treated patients with acute myeloid leukemia. | Blood 20120920 |
Clofarabine plus low-dose cytarabine followed by clofarabine plus low-dose cytarabine alternating with decitabine in acute myeloid leukemia frontline therapy for older patients. | Cancer 20120915 |
Global identification of genes regulated by estrogen signaling and demethylation in MCF-7 breast cancer cells. | Biochemical and biophysical research communications 20120914 |
Development of a novel microRNA promoter microarray for ChIP-on-chip assay to identify epigenetically regulated microRNAs. | Biochemical and biophysical research communications 20120914 |
Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations. | Blood 20120906 |
Block of red blood cell maturation in acute erythroid leukemia. | Blood 20120906 |
Epigenetic modulation of the biophysical properties of drug-resistant cell lipids to restore drug transport and endocytic functions. | Molecular pharmaceutics 20120904 |
Clonal cytogenetic abnormalities after tyrosine kinase inhibitor therapy in Ph+ ALL resolution after decitabine therapy. | Pediatric blood & cancer 20120901 |
A DNA methylation signature associated with aberrant promoter DNA hypermethylation of DNMT3B in human colorectal cancer. | European journal of cancer (Oxford, England : 1990) 20120901 |
Differential effects of low-dose decitabine on immune effector and suppressor responses in melanoma-bearing mice. | Cancer immunology, immunotherapy : CII 20120901 |
The challenge of individualised risk assessment and therapy planning in elderly high-risk myelodysplastic syndromes (MDS) patients. | Annals of hematology 20120901 |
Deferasirox treatment for myelodysplastic syndromes: 'real-life' efficacy and safety in a single-institution patient population. | Annals of hematology 20120901 |
Allogeneic hematopoietic cell transplantation in patients age 60-70 years with de novo high-risk myelodysplastic syndrome or secondary acute myelogenous leukemia: comparison with patients lacking donors who received azacitidine. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120901 |
Efficacy of hypomethylating agents in therapy-related myelodysplastic syndromes. | Leukemia research 20120901 |
Generalized skin reactions in patients with MDS and CMML treated with azacitidine: Effective management with concomitant prednisolone. | Leukemia research 20120901 |
Hepatoma cells from mice deficient in glycine N-methyltransferase have increased RAS signaling and activation of liver kinase B1. | Gastroenterology 20120901 |
Anti-invasive effects of decitabine, a DNA methyltransferase inhibitor, through tightening of tight junctions and inhibition of matrix metalloproteinase activities in AGS human gastric carcinoma cells. | Oncology reports 20120901 |
Decitabine, a DNA methyltransferase inhibitor, induces apoptosis in human leukemia cells through intracellular reactive oxygen species generation. | International journal of oncology 20120901 |
Targeting the MAGE A3 antigen in pancreatic cancer. | Surgery 20120901 |
Epigenetic induction of adaptive immune response in multiple myeloma: sequential azacitidine and lenalidomide generate cancer testis antigen-specific cellular immunity. | British journal of haematology 20120901 |
Genomic methylation profiling combined with gene expression microarray reveals the aberrant methylation mechanism involved in nasopharyngeal carcinoma taxol resistance. | Anti-cancer drugs 20120901 |
5'-Aza-dC sensitizes paraquat toxic effects on PC12 cell. | Neuroscience letters 20120822 |
Improving the outlook for myelodysplastic syndrome. | Journal of the National Cancer Institute 20120822 |
Widespread existence of cytosine methylation in yeast DNA measured by gas chromatography/mass spectrometry. | Analytical chemistry 20120821 |
CIITA is silenced by epigenetic mechanisms that prevent the recruitment of transactivating factors in rhabdomyosarcoma cells. | International journal of cancer 20120815 |
MicroRNA-34b functions as a potential tumor suppressor in endometrial serous adenocarcinoma. | International journal of cancer 20120815 |
Expression pattern of SVEP1 alternatively-spliced forms. | Gene 20120815 |
Grape seed proanthocyanidins reactivate silenced tumor suppressor genes in human skin cancer cells by targeting epigenetic regulators. | Toxicology and applied pharmacology 20120815 |
Case report of isochromosome 17q in acute myeloid leukemia with myelodysplasia-related changes after treatment with a hypomethylating agent. | Genetics and molecular research : GMR 20120806 |
Synergetic effects of DNA demethylation and histone deacetylase inhibition in primary rat hepatocytes. | Investigational new drugs 20120801 |
Frequent epigenetic inactivation of the chaperone SGNE1/7B2 in human gliomas. | International journal of cancer 20120801 |
Pretransplantation therapy with azacitidine vs induction chemotherapy and posttransplantation outcome in patients with MDS. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120801 |
5-azacitidine efficacy and safety in patients aged >65 years with myelodysplastic syndromes outside clinical trials. | Leukemia & lymphoma 20120801 |
Clone-derived human AF-amniotic fluid stem cells are capable of skeletal myogenic differentiation in vitro and in vivo. | Journal of tissue engineering and regenerative medicine 20120801 |
Changes in micro RNA expression in a wild tuber-bearing Solanum species induced by 5-Azacytidine treatment. | Plant cell reports 20120801 |
Differential TERT promoter methylation and response to 5-aza-2'-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death. | Genes, chromosomes & cancer 20120801 |
Cell cycle regulation of human endometrial stromal cells during decidualization. | Reproductive sciences (Thousand Oaks, Calif.) 20120801 |
A patient with acute megakaryoblastic leukaemia who achieved CRi after decitabine treatment. | Leukemia research 20120801 |
Transcriptional silencing of the inhibin-α gene in human gastric carcinoma cells. | International journal of oncology 20120801 |
Treatment of chronic myelomonocytic leukemia with 5-Azacitidine: a case series and literature review. | Leukemia research 20120801 |
Rewiring drug-activated p53-regulatory network from suppressing to promoting tumorigenesis. | Journal of molecular cell biology 20120801 |
Decorin promotes myogenic differentiation and mdx mice therapeutic effects after transplantation of rat adipose-derived stem cells. | Cytotherapy 20120801 |
5-Aza-2'-deoxycytidine induces cytotoxicity in BGC-823 cells via DNA methyltransferase 1 and 3a independent of p53 status. | Oncology reports 20120801 |
The TCF4/β-catenin pathway and chromatin structure cooperate to regulate D-glucuronyl C5-epimerase expression in breast cancer. | Epigenetics 20120801 |
Screening for cytotoxic compounds in poor-prognostic chronic lymphocytic leukemia. | Anticancer research 20120801 |
Unfavorable, complex, and monosomal karyotypes: the most challenging forms of acute myeloid leukemia. | Oncology (Williston Park, N.Y.) 20120801 |
Nickel-induced epithelial-mesenchymal transition by reactive oxygen species generation and E-cadherin promoter hypermethylation. | The Journal of biological chemistry 20120720 |
Multicenter, randomized, open-label, phase III trial of decitabine versus patient choice, with physician advice, of either supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed acute myeloid leukemia. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120720 |
Relationship between chromatin structure and sensitivity to molecularly targeted auger electron radiation therapy. | International journal of radiation oncology, biology, physics 20120715 |
Factors influencing epigenetic mechanisms and related diseases. | Antioxidants & redox signaling 20120715 |
Methylation of the calcium channel regulatory subunit α2δ-3 (CACNA2D3) predicts site-specific relapse in oestrogen receptor-positive primary breast carcinomas. | British journal of cancer 20120710 |
Promoter demethylation of Keap1 gene in human diabetic cataractous lenses. | Biochemical and biophysical research communications 20120706 |
Twist contributes to hormone resistance in breast cancer by downregulating estrogen receptor-α. | Oncogene 20120705 |
Epigenetic regulation by decitabine of melanoma differentiation in vitro and in vivo. | International journal of cancer 20120701 |
Durable complete remission after single agent decitabine in AML relapsing in extramedullary sites after allo-SCT. | Bone marrow transplantation 20120701 |
Generation of a cholesterol-independent, non-GS NS0 cell line through chemical treatment and application for high titer antibody production. | Biotechnology and bioengineering 20120701 |
Rap1GAP regulates renal cell carcinoma invasion. | Cancer letters 20120701 |
Methylome of fetal and maternal monocytes and macrophages at the feto-maternal interface. | American journal of reproductive immunology (New York, N.Y. : 1989) 20120701 |
5-Aza-2'-deoxycytidine induced growth inhibition of leukemia cells through modulating endogenous cholesterol biosynthesis. | Molecular & cellular proteomics : MCP 20120701 |
Neutrophilic panniculitis following azacitidine treatment for myelodysplastic syndromes. | Leukemia research 20120701 |
Treatment with the cancer drugs decitabine and doxorubicin induces human skin keratinocytes to express Oct4 and the OCT4 regulator mir-145. | The Journal of dermatology 20120701 |
Epigenetic regulation of PRAME in acute myeloid leukemia is different compared to CD34+ cells from healthy donors: effect of 5-AZA treatment. | Leukemia research 20120701 |
Azacitidine differentially affects CD4(pos) T-cell polarization in vitro and in vivo in high risk myelodysplastic syndromes. | Leukemia research 20120701 |
cAMP response element-binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120701 |
Gene silencing of EREG mediated by DNA methylation and histone modification in human gastric cancers. | Laboratory investigation; a journal of technical methods and pathology 20120701 |
Assessing signaling pathways associated with in vitro resistance to cytotoxic agents in AML. | Leukemia research 20120701 |
Epigenetics and vitrification of embryos: one step forward and many raised equivocal questions. | Fertility and sterility 20120701 |
Epigenetic inactivation of PLCD1 in chronic myeloid leukemia. | International journal of molecular medicine 20120701 |
Effect of 5-aza-2'-deoxycytidine on methylation of the putative imprinted control region of H19 during the in vitro development of vitrified bovine two-cell embryos. | Fertility and sterility 20120701 |
5-aza-2'-deoxycytidine improves the sensitivity of endometrial cancer cells to progesterone therapy. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20120701 |
Myelodysplastic syndromes: therapy and outlook. | The American journal of medicine 20120701 |
Immunization with WT1-derived peptides by tattooing inhibits the growth of TRAMP-C2 prostate tumor in mice. | Journal of immunotherapy (Hagerstown, Md. : 1997) 20120701 |
Prostaglandin E2 induces growth inhibition, apoptosis and differentiation in T and B cell-derived acute lymphoblastic leukemia cell lines (CCRF-CEM and Nalm-6). | Prostaglandins, leukotrienes, and essential fatty acids 20120701 |
Expression and functions of μ-opioid receptors and cannabinoid receptors type 1 in T lymphocytes. | Annals of the New York Academy of Sciences 20120701 |
[Effective treatment of myelodysplastic syndromes-refractory anemia with excess blasts type II by decitabine: a case report]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20120701 |
[Epigenetic variation of the choriflowered--symflowered character in the symflowered sugar beet line SOAN-14]. | Genetika 20120701 |
Even-skipped homeobox 1 is frequently hypermethylated in prostate cancer and predicts PSA recurrence. | British journal of cancer 20120626 |
Clinical and pharmacodynamic activity of bortezomib and decitabine in acute myeloid leukemia. | Blood 20120621 |
Long-term outcome of higher-risk MDS patients treated with azacitidine: an update of the GFM compassionate program cohort. | Blood 20120621 |
Development and validation of a liquid chromatography-tandem mass spectrometry method for quantification of decitabine in rat plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120615 |
XAF1 is frequently methylated in human esophageal cancer. | World journal of gastroenterology 20120614 |
Concomitant lethal mutagenesis of human immunodeficiency virus type 1. | Journal of molecular biology 20120608 |
Correlation between T-cadherin gene expression and aberrant methylation of T-cadherin promoter in human colon carcinoma cells. | Medical oncology (Northwood, London, England) 20120601 |
Reactivation of Syk gene by AZA suppresses metastasis but not proliferation of breast cancer cells. | Medical oncology (Northwood, London, England) 20120601 |
Azacitidine has limited activity in 'real life' patients with MDS and AML: a single centre experience. | Hematological oncology 20120601 |
Cytosine methylation in miR-153 gene promoters increases the expression of holocarboxylase synthetase, thereby increasing the abundance of histone H4 biotinylation marks in HEK-293 human kidney cells. | The Journal of nutritional biochemistry 20120601 |
Inactivation of the putative suppressor gene DOK1 by promoter hypermethylation in primary human cancers. | International journal of cancer 20120601 |
Epigenetic silencing of the tumor suppressor klotho in human breast cancer. | Breast cancer research and treatment 20120601 |
Down-regulation of microRNA-34a* in rheumatoid arthritis synovial fibroblasts promotes apoptosis resistance. | Arthritis and rheumatism 20120601 |
Jack of all nectars, master of most: DNA methylation and the epigenetic basis of niche width in a flower-living yeast. | Molecular ecology 20120601 |
Differential fucosyltransferase IV expression in squamous carcinoma cells is regulated by promoter methylation. | Cellular & molecular biology letters 20120601 |
Curcumin causes promoter hypomethylation and increased expression of FANCF gene in SiHa cell line. | Molecular and cellular biochemistry 20120601 |
Decitabine triphosphate levels in peripheral blood mononuclear cells from patients receiving prolonged low-dose decitabine administration: a pilot study. | Cancer chemotherapy and pharmacology 20120601 |
Outcome of acute myeloid leukaemia following myelodysplastic syndrome after azacitidine treatment failure. | British journal of haematology 20120601 |
TROP2 is epigenetically inactivated and modulates IGF-1R signalling in lung adenocarcinoma. | EMBO molecular medicine 20120601 |
Combination of azacitidine and ESA in myelodysplastic patients: the need for prospective studies. | Leukemia research 20120601 |
microRNA-155 is downregulated in gastric cancer cells and involved in cell metastasis. | Oncology reports 20120601 |
Treatment of nuclear-donor cells or cloned zygotes with chromatin-modifying agents increases histone acetylation but does not improve full-term development of cloned cattle. | Cellular reprogramming 20120601 |
DNA demethylating agent decitabine increases AQP5 expression and restores salivary function. | Journal of dental research 20120601 |
Silencing of Wnt5a during colon cancer metastasis involves histone modifications. | Epigenetics 20120601 |
Human cytomegalovirus infection is sensitive to the host cell DNA methylation state and alters global DNA methylation capacity. | Epigenetics 20120601 |
Chronic myelomonocytic leukemia: 2012 update on diagnosis, risk stratification, and management. | American journal of hematology 20120601 |
Pharmacological unmasking microarray approach-based discovery of novel DNA methylation markers for hepatocellular carcinoma. | Journal of Korean medical science 20120601 |
Chemical and physical modulation of antibiotic activity in emericella species. | Chemistry & biodiversity 20120601 |
[Effect of proliferation inhibition and PTEN gene expression induced by decitabine combined with daunorubicin on HL-60 cell line]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20120601 |
Wnt inhibitory factor 1 induces apoptosis and inhibits cervical cancer growth, invasion and angiogenesis in vivo. | Oncogene 20120531 |
Epigenetic reprogramming reverses the relapse-specific gene expression signature and restores chemosensitivity in childhood B-lymphoblastic leukemia. | Blood 20120531 |
RNA-dependent inhibition of ribonucleotide reductase is a major pathway for 5-azacytidine activity in acute myeloid leukemia. | Blood 20120531 |
Azacitidine: a review of its use in the management of myelodysplastic syndromes/acute myeloid leukaemia. | Drugs 20120528 |
Anti-tumor effect of 5-aza-2'-deoxycytidine by inhibiting telomerase activity in hepatocellular carcinoma cells. | World journal of gastroenterology 20120521 |
Azacitidine-associated Sweet's syndrome. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120515 |
Aberrant methylation of SPARC in human hepatocellular carcinoma and its clinical implication. | World journal of gastroenterology 20120507 |
Epigenetic regulation of 5-lipoxygenase in the phenotypic plasticity of valvular interstitial cells associated with aortic valve stenosis. | FEBS letters 20120507 |
5-azacytidine and decitabine exert proapoptotic effects on neoplastic mast cells: role of FAS-demethylation and FAS re-expression, and synergism with FAS-ligand. | Blood 20120503 |
Promoter hypermethylation of DNA damage response genes in hepatocellular carcinoma. | Cell biology international 20120501 |
Transcription of nephrin-Neph3 gene pair is synergistically activated by WT1 and NF-κB and silenced by DNA methylation. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120501 |
Epigenetic regulation of nuclear PI-PLCbeta1 signaling pathway in low-risk MDS patients during azacitidine treatment. | Leukemia 20120501 |
Safety, efficacy and biological predictors of response to sequential azacitidine and lenalidomide for elderly patients with acute myeloid leukemia. | Leukemia 20120501 |
DNMT3A mutations and response to the hypomethylating agent decitabine in acute myeloid leukemia. | Leukemia 20120501 |
Proteomic analysis identifies differentially expressed proteins in AML1/ETO acute myeloid leukemia cells treated with DNMT inhibitors azacitidine and decitabine. | Leukemia research 20120501 |
Change in gene expression profiles of secreted frizzled-related proteins (SFRPs) by sodium butyrate in gastric cancers: induction of promoter demethylation and histone modification causing inhibition of Wnt signaling. | International journal of oncology 20120501 |
Achieving a cure for HIV infection: do we have reasons to be optimistic? | The Journal of antimicrobial chemotherapy 20120501 |
Commentary on paper: 5-Aza-2'-deoxycytidine increases sialyl Lewis X on MUC1 by stimulating β-galactoside:α2,3-sialyltransferase 6 gene (Chachadi et al.). | The international journal of biochemistry & cell biology 20120501 |
Can soy phytoestrogens decrease DNA methylation in BRCA1 and BRCA2 oncosuppressor genes in breast cancer? | Omics : a journal of integrative biology 20120501 |
Targeting the IGF-1R signaling and mechanisms for epigenetic gene silencing in human multiple myeloma. | Upsala journal of medical sciences 20120501 |
Decitabine and vorinostat cooperate to sensitize colon carcinoma cells to Fas ligand-induced apoptosis in vitro and tumor suppression in vivo. | Journal of immunology (Baltimore, Md. : 1950) 20120501 |
Epigenetic regulation of reelin and brain-derived neurotrophic factor genes in long-term potentiation in rat medial prefrontal cortex. | Neurobiology of learning and memory 20120501 |
Activation and epigenetic regulation of DNA transposon nDart1 in rice. | Plant & cell physiology 20120501 |
Epigenetic resensitization to platinum in ovarian cancer. | Cancer research 20120501 |
5-azacytosine compounds in medicinal chemistry: current stage and future perspectives. | Future medicinal chemistry 20120501 |
[Dynamic changes of gene expression profiles during cardiomyogenesis of human marrow mesenchymal stem cells]. | Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20120501 |
[Effects of 5-Aza-2'-deoxycitydine and trichostatin A on expression and methylation of CHFR in human laryngreal carcinoma cell line]. | Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 20120501 |
The differentiating and apoptotic effects of 2-aza-5'-deoxycytidine are dependent on the PU.1 expression level in PU.1-transgenic K562 cells. | Biochemical and biophysical research communications 20120420 |
[A case report of undifferentiated connective tissue disease associated myelodysplastic]. | Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20120418 |
NT5E (CD73) is epigenetically regulated in malignant melanoma and associated with metastatic site specificity. | British journal of cancer 20120410 |
Identification of methylation-dependent regulatory elements for intergenic miRNAs in human H4 cells. | Biochemical and biophysical research communications 20120406 |
Azacitidine augments expansion of regulatory T cells after allogeneic stem cell transplantation in patients with acute myeloid leukemia (AML). | Blood 20120405 |
Azacitidine after allo-SCT: the good without the bad? | Blood 20120405 |
Epigenetic repression of regulator of G-protein signaling 2 promotes androgen-independent prostate cancer cell growth. | International journal of cancer 20120401 |
Interest of the association azacitidine-lenalidomide as frontline therapy in high-risk myelodysplasia or acute myeloid leukemia with complex karyotype. | Leukemia 20120401 |
Eosinophilic pneumonia associated with azacitidine in a patient with myelodysplastic syndrome. | Respiratory care 20120401 |
MicroRNA regulation via DNA methylation during the morula to blastocyst transition in mice. | Molecular human reproduction 20120401 |
AKT signaling pathway activated by HIN-1 methylation in non-small cell lung cancer. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20120401 |
Hypermethylation of Sox17 gene is useful as a molecular diagnostic application in early gastric cancer. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20120401 |
DNA methylation contributes to the regulation of sclerostin expression in human osteocytes. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20120401 |
Does addition of erythropoiesis stimulating agents improve the outcome of higher-risk myelodysplastic syndromes treated with azacitidine? | Leukemia research 20120401 |
Azacitidine in a patient with newly diagnosed acute myeloid leukemia and poor risk cytogenetics: outcomes of prolonged therapy. | Leukemia research 20120401 |
Hypomethylating therapy and autoimmunity in MDS: an enigmatic relationship. | Leukemia research 20120401 |
Suppression of Klotho expression by protein-bound uremic toxins is associated with increased DNA methyltransferase expression and DNA hypermethylation. | Kidney international 20120401 |
Promoter methylation of MGMT, MLH1 and RASSF1A tumor suppressor genes in head and neck squamous cell carcinoma: pharmacological genome demethylation reduces proliferation of head and neck squamous carcinoma cells. | Oncology reports 20120401 |
Demethylation restores SN38 sensitivity in cells with acquired resistance to SN38 derived from human cervical squamous cancer cells. | Oncology reports 20120401 |
SFRP1 promoter methylation and expression in human trabecular meshwork cells. | Experimental eye research 20120401 |
Diagnostic and prognostic utility of methylation and protein expression patterns of myopodin in colon cancer. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20120401 |
Discovery of drugs that possess activity against feline leukemia virus. | The Journal of general virology 20120401 |
Activity of a novel combined antiretroviral therapy of gemcitabine and decitabine in a mouse model for HIV-1. | Antimicrobial agents and chemotherapy 20120401 |
DNA demethylation increases sensitivity of neuroblastoma cells to chemotherapeutic drugs. | Biochemical pharmacology 20120401 |
AZA-ESA combo: a new standard for higher risk MDS? | Leukemia research 20120401 |
Human first-trimester chorionic villi have a myogenic potential. | Cell and tissue research 20120401 |
Mantle cell lymphoma displays a homogenous methylation profile: a comparative analysis with chronic lymphocytic leukemia. | American journal of hematology 20120401 |
The efficiency of in vitro isolation and myogenic differentiation of MSCs derived from adipose connective tissue, bone marrow, and skeletal muscle tissue. | In vitro cellular & developmental biology. Animal 20120401 |
A simple method for high-throughput quantification of genome-wide DNA methylation by fluorescence polarization. | Epigenetics 20120401 |
Promoter methylation regulates cigarette smoke-stimulated cyclooxygenase-2 expression in esophageal squamous cell carcinoma. | Journal of digestive diseases 20120401 |
When should iron chelation therapy be considered in patients with myelodysplasia and other bone marrow failure syndromes with iron overload? | Internal medicine journal 20120401 |
BCL2L10 is a predictive factor for resistance to azacitidine in MDS and AML patients. | Oncotarget 20120401 |
Epigenetic tailoring for the production of anti-infective cytosporones from the marine fungus Leucostoma persoonii. | Marine drugs 20120401 |
Reactivation of Silenced WT1 Transgene by Hypomethylating Agents - Implications for in vitro Modeling of Chemoimmunotherapy. | Immune network 20120401 |
DNA methylation-associated silencing of tumor-suppressor microRNAs in cancer. | Oncogene 20120329 |
Using peripheral blood circulating DNAs to detect CpG global methylation status and genetic mutations in patients with myelodysplastic syndrome. | Biochemical and biophysical research communications 20120323 |
Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells. | Cancer cell 20120320 |
Identification of the A kinase anchor protein 12 (AKAP12) gene as a candidate tumor suppressor of hepatocellular carcinoma. | Journal of surgical oncology 20120315 |
Oligoamine analogues in combination with 2-difluoromethylornithine synergistically induce re-expression of aberrantly silenced tumour-suppressor genes. | The Biochemical journal 20120315 |
Genome-wide miRNA expression profiling identifies miR-9-3 and miR-193a as targets for DNA methylation in non-small cell lung cancers. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120315 |
Interstitial lung disease associated with azacitidine use: a case report. | American journal of therapeutics 20120301 |
Valproic acid: growth inhibition of head and neck cancer by induction of terminal differentiation and senescence. | Head & neck 20120301 |
The DNA methyltransferase inhibitors zebularine and decitabine induce mitochondria-mediated apoptosis and DNA damage in p53 mutant leukemic T cells. | International journal of cancer 20120301 |
Feasibility of hypomethylating agents followed by allogeneic hematopoietic cell transplantation in patients with myelodysplastic syndrome. | Bone marrow transplantation 20120301 |
Aberrant methylation of RASSF2A in human pancreatic ductal adenocarcinoma and its relation to clinicopathologic features. | Pancreas 20120301 |
A case of Sweet's syndrome due to 5-Azacytidine and vorinostat in a patient with NK/T cell lymphoma. | Cutaneous and ocular toxicology 20120301 |
Azacitidine for treatment of imminent relapse in MDS or AML patients after allogeneic HSCT: results of the RELAZA trial. | Leukemia 20120301 |
How to manage lower-risk myelodysplastic syndromes. | Leukemia 20120301 |
Pilot study on combination of azacitidine and low-dose cytarabine for patients with refractory anemia with excess blast. | Annals of hematology 20120301 |
Down-regulation of CXCL12 by DNA hypermethylation and its involvement in gastric cancer metastatic progression. | Digestive diseases and sciences 20120301 |
A multicenter phase II trial of decitabine as first-line treatment for older patients with acute myeloid leukemia judged unfit for induction chemotherapy. | Haematologica 20120301 |
DNA demethylation by 5-aza-2-deoxycytidine treatment abrogates 17 beta-estradiol-induced cell growth and restores expression of DNA repair genes in human breast cancer cells. | Cancer letters 20120301 |
Pharmacological genome demethylation increases radiosensitivity of head and neck squamous carcinoma cells. | International journal of molecular medicine 20120301 |
MDS: Refining existing therapy through improved biologic insights. | Blood reviews 20120301 |
Downregulation of MUC1 expression and its recognition by CD8⁺ T cells on the surface of malignant pleural mesothelioma cells treated with HDACi. | European journal of immunology 20120301 |
Demethylation of the FCER1G promoter leads to FcεRI overexpression on monocytes of patients with atopic dermatitis. | Allergy 20120301 |
Atraumatic splenic rupture in patients with myelodysplastic syndromes: report of a case occurred during treatment with 5-azacitidine and review of the literature. | Leukemia research 20120301 |
RUNX3 is involved in caspase-3-dependent apoptosis induced by a combination of 5-aza-CdR and TSA in leukaemia cell lines. | Journal of cancer research and clinical oncology 20120301 |
Dynamic CpG-DNA methylation of Il10 and Il19 in CD4+ T lymphocytes and macrophages: effects on tissue-specific gene expression. | Klinische Padiatrie 20120301 |
Diversification of hAT transposase paralogues in the sugarcane genome. | Molecular genetics and genomics : MGG 20120301 |
Optimizing hypomethylating agents in myelodysplastic syndromes. | Current opinion in hematology 20120301 |
Increased proliferation and chemosensitivity of human mesenchymal stromal cells expressing fusion yeast cytosine deaminase. | Stem cell research 20120301 |
5-Aza-2'-deoxycytidine increases the sensitivity of human bone marrow mesenchymal stem cells to chemotherapeutic agents by demethylation of p73. | Journal of pediatric hematology/oncology 20120301 |
Decitabine for acute myeloid leukemia. | Expert review of anticancer therapy 20120301 |
Antiproliferative and antitumor effects of azacitidine against the human myelodysplastic syndrome cell line SKM-1. | Anticancer research 20120301 |
[Effect of methylation inhibitor on EphB4 gene expression, proliferation and apoptosis in CEM cells]. | Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20120301 |
Transcriptional control in cardiac progenitors: Tbx1 interacts with the BAF chromatin remodeling complex and regulates Wnt5a. | PLoS genetics 20120301 |
[Therapeutic effect of in vitro 5-aza-2'-deoxycytidine combined with imatinib on gastrointestinal stromal tumor]. | Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20120301 |
Gene reactivation by 5-aza-2'-deoxycytidine-induced demethylation requires SRCAP-mediated H2A.Z insertion to establish nucleosome depleted regions. | PLoS genetics 20120301 |
[Cost-effectiveness analysis of azacitidine for myelodysplastic syndromes in Japan]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20120301 |
[Effect of nesprin-1 in the differentiation of mouse embryonic stem cells into cardiomyocytes]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20120301 |
Position effect variegation and epigenetic modification of a transgene in a pig model. | Genetics and molecular research : GMR 20120216 |
Azacitidine for the treatment of patients with acute myeloid leukemia: report of 82 patients enrolled in an Italian Compassionate Program. | Cancer 20120215 |
Genome-wide DNA methylation level analysis by micellar electrokinetic chromatography and laser-induced fluorescence detection after treatment of cell lines with azacytidine and antifolates. | Analytical biochemistry 20120215 |
Study on RIZ1 gene promoter methylation status in human esophageal squamous cell carcinoma. | World journal of gastroenterology 20120214 |
Effects of tetrahydrouridine on pharmacokinetics and pharmacodynamics of oral decitabine. | Blood 20120202 |
ENDOGLIN/CD105 is expressed in KIT positive cells in the gut and in gastrointestinal stromal tumours. | Journal of cellular and molecular medicine 20120201 |
Inflammation-induced up-regulation of TLR2 expression in human endothelial cells is independent of differential methylation in the TLR2 promoter CpG island. | Innate immunity 20120201 |
CpG methylation patterns and decitabine treatment response in acute myeloid leukemia cells and normal hematopoietic precursors. | Leukemia 20120201 |
A phase I study of 5-azacytidine and erlotinib in advanced solid tumor malignancies. | Cancer chemotherapy and pharmacology 20120201 |
Histone H4 deacetylation down-regulates catalase gene expression in doxorubicin-resistant AML subline. | Cell biology and toxicology 20120201 |
Heparanase expression is associated with histone modifications in glioblastoma. | International journal of oncology 20120201 |
In utero exposures, infant growth, and DNA methylation of repetitive elements and developmentally related genes in human placenta. | Environmental health perspectives 20120201 |
In vitro study of the differentiation of bone marrow stromal cells into cardiomyocyte-like cells. | Molecular and cellular biochemistry 20120201 |
Effect of CpG island methylation on microRNA expression in the k-562 cell line. | Biochemical genetics 20120201 |
Modulation of volatile organic compound formation in the Mycodiesel-producing endophyte Hypoxylon sp. CI-4. | Microbiology (Reading, England) 20120201 |
Analysis of aberrant methylation in DNA repair genes during malignant transformation of human bronchial epithelial cells induced by cadmium. | Toxicological sciences : an official journal of the Society of Toxicology 20120201 |
Progression of prostate carcinogenesis and dietary methyl donors: temporal dependence. | Cancer prevention research (Philadelphia, Pa.) 20120201 |
CRABP-II methylation: a critical determinant of retinoic acid resistance of medulloblastoma cells. | Molecular oncology 20120201 |
Deletion or epigenetic silencing of AJAP1 on 1p36 in glioblastoma. | Molecular cancer research : MCR 20120201 |
Influence of epigenetic modifications of the interleukin-10 promoter on IL10 gene expression. | European journal of oral sciences 20120201 |
p53-Independent, normal stem cell sparing epigenetic differentiation therapy for myeloid and other malignancies. | Seminars in oncology 20120201 |
Epigenetic modulation to enable antigen-specific T-cell therapy of colorectal cancer. | Journal of immunotherapy (Hagerstown, Md. : 1997) 20120201 |
[Decitabine for treatment of myelodysplastic syndrome in an elderly patient and review of literature]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20120201 |
Novel transmembrane receptor involved in phagosome transport of lysozymes and β-hexosaminidase in the enteric protozoan Entamoeba histolytica. | PLoS pathogens 20120201 |
[Decitabine inhibits cell proliferation and induces apoptosis of all-trans retinoid acid-resistant acute promyelocytic leukemia NB4-R2 cell line]. | Zhongguo shi yan xue ye xue za zhi 20120201 |
Rapid turnover of DNA methylation in human cells. | Epigenetics 20120201 |
A long road for stem cells to cure sick hearts: update on recent clinical trials. | Korean circulation journal 20120201 |
[Cell fusion as a key mechanism for cell-based therapy towards Duchenne muscular dystrophy]. | Seikagaku. The Journal of Japanese Biochemical Society 20120201 |
[The comparison of short-term efficacies between decitabine and HA regimen for MDS/AML patients]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20120201 |
DNA methylation-mediated silencing of nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) in glioma cell lines. | International journal of cancer 20120115 |
Stem cell gene SALL4 suppresses transcription through recruitment of DNA methyltransferases. | The Journal of biological chemistry 20120113 |
DNA methylation of the 5'-untranslated region at +298 and +351 represses BACE1 expression in mouse BV-2 microglial cells. | Biochemical and biophysical research communications 20120106 |
Satellite 2 demethylation induced by 5-azacytidine is associated with missegregation of chromosomes 1 and 16 in human somatic cells. | Mutation research 20120103 |
5-Azacytidine induces cardiac differentiation of human umbilical cord-derived mesenchymal stem cells by activating extracellular regulated kinase. | Stem cells and development 20120101 |
5-Azacytidine makes human preadipocytes able to differentiate into mesoderm-derived cell lineages. | Stem cells and development 20120101 |
Phase II study of the histone deacetylase inhibitor belinostat (PXD101) for the treatment of myelodysplastic syndrome (MDS). | Annals of hematology 20120101 |
Azacitidine in patients with acute myeloid leukemia medically unfit for or resistant to chemotherapy: a multicenter phase I/II study. | Leukemia & lymphoma 20120101 |
Mutations in epigenetic modifiers in myeloid malignancies and the prospect of novel epigenetic-targeted therapy. | Advances in hematology 20120101 |
Azacitidine in a patient with myelodysplastic syndrome: Impact of switching from a 5-day to the approved 7-day dosing schedule. | Leukemia research 20120101 |
HSPB8 is methylated in hematopoietic malignancies and overexpression of HSPB8 exhibits antileukemia effect. | Experimental hematology 20120101 |
The combination of angiotensin II and 5-azacytidine promotes cardiomyocyte differentiation of rat bone marrow mesenchymal stem cells. | Molecular and cellular biochemistry 20120101 |
Trichostatin a promotes cardiomyocyte differentiation of rat mesenchymal stem cells after 5-azacytidine induction or during coculture with neonatal cardiomyocytes via a mechanism independent of histone deacetylase inhibition. | Cell transplantation 20120101 |
Epigenetic drug discovery: targeting DNA methyltransferases. | Journal of biomolecular screening 20120101 |
Differentiation potential of human mesenchymal stem cells derived from adipose tissue and bone marrow to sinus node-like cells. | Molecular medicine reports 20120101 |
A cost-effectiveness analysis of using azacitidine vs. decitabine in treating patients with myelodysplastic syndromes. | Journal of medical economics 20120101 |
5-Aza-2'-deoxycytidine reactivates gene expression via degradation of pRb pocket proteins. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120101 |
Effect of 5-Aza-2'-deoxycytidine on SLC22A18 in glioma U251 cells. | Molecular medicine reports 20120101 |
Interstitial pneumonitis--An important differential diagnosis for pulmonary sepsis in haematology patients. | Leukemia research 20120101 |
Oxidative Stress Induced by MnSOD-p53 Interaction: Pro- or Anti-Tumorigenic? | Journal of signal transduction 20120101 |
Neurospora crassa Light Signal Transduction Is Affected by ROS. | Journal of signal transduction 20120101 |
CRABP-II- and FABP5-independent all-trans retinoic acid resistance in COLO 16 human cutaneous squamous cancer cells. | Experimental dermatology 20120101 |
Neonatal exposure to estradiol/bisphenol A alters promoter methylation and expression of Nsbp1 and Hpcal1 genes and transcriptional programs of Dnmt3a/b and Mbd2/4 in the rat prostate gland throughout life. | Endocrinology 20120101 |
Signature of VDR miRNAs and epigenetic modulation of vitamin D signaling in melanoma cell lines. | Anticancer research 20120101 |
Antiretroviral activity of 5-azacytidine during treatment of a HTLV-1 positive myelodysplastic syndrome with autoimmune manifestations. | Virology journal 20120101 |
Combination strategies in myelodysplastic syndromes. | International journal of hematology 20120101 |
5-Azacytidine is insufficient for cardiogenesis in human adipose-derived stem cells. | Journal of negative results in biomedicine 20120101 |
Emerging therapies in hematopoietic stem cell transplantation. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120101 |
Monitoring and prevention of relapse after allogeneic hematopoietic cell transplantation for myeloid malignancies. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120101 |
Engineered myocardial tissues constructed in vivo using cardiomyocyte-like cells derived from bone marrow mesenchymal stem cells in rats. | Journal of biomedical science 20120101 |
HIV infection and HERV expression: a review. | Retrovirology 20120101 |
Monitoring of methylation changes in 9p21 region in patients with myelodysplastic syndromes and acute myeloid leukemia. | Neoplasma 20120101 |
Defining the sister rat mammary tumor cell lines HH-16 cl.2/1 and HH-16.cl.4 as an in vitro cell model for Erbb2. | PloS one 20120101 |
Effects of a novel DNA methyltransferase inhibitor Zebularine on human lens epithelial cells. | Molecular vision 20120101 |
Regulation of opioid and cannabinoid receptor genes in human neuroblastoma and T cells by the epigenetic modifiers trichostatin A and 5-aza-2'-deoxycytidine. | Neuroimmunomodulation 20120101 |
Sca-1+ cardiosphere-derived cells are enriched for Isl1-expressing cardiac precursors and improve cardiac function after myocardial injury. | PloS one 20120101 |
Bisulfite sequencing reveals that Aspergillus flavus holds a hollow in DNA methylation. | PloS one 20120101 |
[Demethylating medication in myelodysplastic syndrome]. | Nederlands tijdschrift voor geneeskunde 20120101 |
Oncolytic virotherapy for hematological malignancies. | Advances in virology 20120101 |
Molecular Characterization of a Patient's Small Cell Carcinoma of the Ovary of the Hypercalcemic Type. | Journal of Cancer 20120101 |
TET2 mutations are associated with specific 5-methylcytosine and 5-hydroxymethylcytosine profiles in patients with chronic myelomonocytic leukemia. | PloS one 20120101 |
The co-presence of deletion 7q, 20q and inversion 16 in therapy-related acute myeloid leukemia developed secondary to treatment of breast cancer with cyclophosphamide, doxorubicin, and radiotherapy: a case report. | Journal of medical case reports 20120101 |
DNMT inhibitors and HDAC inhibitors regulate E-cadherin and Bcl-2 expression in endometrial carcinoma in vitro and in vivo. | Chemotherapy 20120101 |
Particulate matter Air Pollution induces hypermethylation of the p16 promoter Via a mitochondrial ROS-JNK-DNMT1 pathway. | Scientific reports 20120101 |
Role of human nucleoside transporters in the uptake and cytotoxicity of azacitidine and decitabine. | Nucleosides, nucleotides & nucleic acids 20120101 |
Induction of sodium/iodide symporter (NIS) expression and radioiodine uptake in non-thyroid cancer cells. | PloS one 20120101 |
Transcriptional silencing of the Wnt-antagonist DKK1 by promoter methylation is associated with enhanced Wnt signaling in advanced multiple myeloma. | PloS one 20120101 |
A novel classification of lung cancer into molecular subtypes. | PloS one 20120101 |
Instability of (CTG)n•(CAG)n trinucleotide repeats and DNA synthesis. | Cell & bioscience 20120101 |
Decreased expression of retinoblastoma protein-interacting zinc-finger gene 1 in human esophageal squamous cell cancer by DNA methylation. | Clinical laboratory 20120101 |
[MDS]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20120101 |
Different involvement of DNA methylation and histone deacetylation in the expression of solute-carrier transporters in 4 colon cancer cell lines. | Biological & pharmaceutical bulletin 20120101 |
NYESO-1/LAGE-1s and PRAME are targets for antigen specific T cells in chondrosarcoma following treatment with 5-Aza-2-deoxycitabine. | PloS one 20120101 |
Cytogenetic and molecular predictors of response in patients with myeloid malignancies without del[5q] treated with lenalidomide. | Journal of hematology & oncology 20120101 |
Screening for epigenetically masked genes in colorectal cancer Using 5-Aza-2'-deoxycytidine, microarray and gene expression profile. | Cancer genomics & proteomics 20120101 |
Methylation of Wnt7a is modulated by DNMT1 and cigarette smoke condensate in non-small cell lung cancer. | PloS one 20120101 |
Epigenetic disregulation in oral cancer. | International journal of molecular sciences 20120101 |
The endogenous retrovirus ENS-1 provides active binding sites for transcription factors in embryonic stem cells that specify extra embryonic tissue. | Retrovirology 20120101 |
In planta assays involving epigenetically silenced genes reveal inhibition of cytosine methylation by genistein. | Plant methods 20120101 |
DNA methylation-independent reversion of gemcitabine resistance by hydralazine in cervical cancer cells. | PloS one 20120101 |
RNA-binding protein Musashi1 modulates glioma cell growth through the post-transcriptional regulation of Notch and PI3 kinase/Akt signaling pathways. | PloS one 20120101 |
DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity. | Radiation oncology (London, England) 20120101 |
Targeted drug regulation on methylation of p53-BAX mitochondrial apoptosis pathway affects the growth of cholangiocarcinoma cells. | The Journal of international medical research 20120101 |
Epigenetic modification of TLRs in leukocytes is associated with increased susceptibility to Salmonella enteritidis in chickens. | PloS one 20120101 |
IL-35 is a novel responsive anti-inflammatory cytokine--a new system of categorizing anti-inflammatory cytokines. | PloS one 20120101 |
Hiwi mediated tumorigenesis is associated with DNA hypermethylation. | PloS one 20120101 |
Rapidly growing ulcer in a patient with neurofibromatosis type I. | Actas dermo-sifiliograficas 20120101 |
Reversin increase the plasticity of bone marrow-derived mesenchymal stem cell for generation of cardiomyocyte in vitro. | Acta medica Indonesiana 20120101 |
Management of cutaneous T cell lymphoma: new and emerging targets and treatment options. | Cancer management and research 20120101 |
Methylation profiling of Epstein-Barr virus immediate-early gene promoters, BZLF1 and BRLF1 in tumors of epithelial, NK- and B-cell origins. | BMC cancer 20120101 |
[5-aza-2'-deoxycytidine-induced inhibition of CDH13 expression and its inhibitory effect on methylation status in human colon cancer cells in vitro and on growth of xenograft in nude mice]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20120101 |
Differential epigenetic regulation of TOX subfamily high mobility group box genes in lung and breast cancers. | PloS one 20120101 |
Effect of cyclic strain on cardiomyogenic differentiation of rat bone marrow derived mesenchymal stem cells. | PloS one 20120101 |
Advances in Virus-Directed Therapeutics against Epstein-Barr Virus-Associated Malignancies. | Advances in virology 20120101 |
A novel intracellular isoform of matrix metalloproteinase-2 induced by oxidative stress activates innate immunity. | PloS one 20120101 |
Plant 45S rDNA clusters are fragile sites and their instability is associated with epigenetic alterations. | PloS one 20120101 |
Symbiodinium transcriptomes: genome insights into the dinoflagellate symbionts of reef-building corals. | PloS one 20120101 |
Epigenetics and autoimmune diseases. | Autoimmune diseases 20120101 |
Sodium iodide symporter for nuclear molecular imaging and gene therapy: from bedside to bench and back. | Theranostics 20120101 |
Azacytidine inhibits the proliferation of human promyelocytic leukemia cells (HL60) by demethylation of MGMT, DAPK and p16 genes. | Hematology (Amsterdam, Netherlands) 20120101 |
Long-term cultured human term placenta-derived mesenchymal stem cells of maternal origin displays plasticity. | Stem cells international 20120101 |
Histone deacetylase inhibitors in cell pluripotency, differentiation, and reprogramming. | Stem cells international 20120101 |
Analysis of embryoid bodies derived from human induced pluripotent stem cells as a means to assess pluripotency. | Stem cells international 20120101 |
A Case of Atypical Delayed and Prolonged Hematologic Toxicity With Azacitidine in Chronic Myelomonocytic Leukemia (CMML) and Review of Literature. | Mediterranean journal of hematology and infectious diseases 20120101 |
Arsenic induces functional re-expression of estrogen receptor α by demethylation of DNA in estrogen receptor-negative human breast cancer. | PloS one 20120101 |
Antiproliferative effects of DNA methyltransferase 3B depletion are not associated with DNA demethylation. | PloS one 20120101 |
Daphnia as an emerging epigenetic model organism. | Genetics research international 20120101 |
Utility of DNA methyltransferase inhibitors for the treatment of myelodysplastic syndromes. | Current pharmaceutical design 20120101 |
Approach to new therapeutics: investigation by the use of MDS-derived cell lines. | Current pharmaceutical design 20120101 |
Influence of nanomaterials on stem cell differentiation: designing an appropriate nanobiointerface. | International journal of nanomedicine 20120101 |
TCUP: A Novel hAT Transposon Active in Maize Tissue Culture. | Frontiers in plant science 20120101 |
Epigenetics modifications and therapeutic prospects in human thyroid cancer. | Frontiers in endocrinology 20120101 |
Acute myeloid leukemia: focus on novel therapeutic strategies. | Clinical Medicine Insights. Oncology 20120101 |
FK228 Analogues Induce Fetal Hemoglobin in Human Erythroid Progenitors. | Anemia 20120101 |
Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism. | PloS one 20120101 |
Demethylation of the coding region triggers the activation of the human testis-specific PDHA2 gene in somatic tissues. | PloS one 20120101 |
The two-component sensor kinase TcsC and its role in stress resistance of the human-pathogenic mold Aspergillus fumigatus. | PloS one 20120101 |
5-Methylcytosine and 5-hydroxymethylcytosine spatiotemporal profiles in the mouse zygote. | PloS one 20120101 |
Directed Fusion of Mesenchymal Stem Cells with Cardiomyocytes via VSV-G Facilitates Stem Cell Programming. | Stem cells international 20120101 |
Cancer-type regulation of MIG-6 expression by inhibitors of methylation and histone deacetylation. | PloS one 20120101 |
Molecular mechanisms of induced pluripotency. | Acta naturae 20120101 |
Diagnosis and therapy of myelodysplastic syndromes in Germany: a retrospective multicenter analysis. | Onkologie 20120101 |
Effect of phenylhexyl isothiocyanate on aberrant histone H3 methylation in primary human acute leukemia. | Journal of hematology & oncology 20120101 |
Safety and efficacy of azacitidine in the treatment of elderly patients with myelodysplastic syndrome. | Clinical interventions in aging 20120101 |
The effects of promoter methylation on downregulation of DAZAP2 in multiple myeloma cell lines. | PloS one 20120101 |
Tamoxifen-induced epigenetic silencing of oestrogen-regulated genes in anti-hormone resistant breast cancer. | PloS one 20120101 |
Outcome of therapy-related myeloid neoplasms treated with azacitidine. | Journal of hematology & oncology 20120101 |
Identification of CBX3 and ABCA5 as putative biomarkers for tumor stem cells in osteosarcoma. | PloS one 20120101 |
Aberrant promoter methylation and expression of UTF1 during cervical carcinogenesis. | PloS one 20120101 |
ING1 and 5-azacytidine act synergistically to block breast cancer cell growth. | PloS one 20120101 |
Murine models of lupus induced by hypomethylated T cells (DNA hypomethylation and lupus…). | Methods in molecular biology (Clifton, N.J.) 20120101 |
Treatment of chronic myelomonocytic leukemia with 5-azacytidine: case reports. | Case reports in hematology 20120101 |
Gene expression profiling of the synergy of 5-aza-2'-deoxycytidine and paclitaxel against renal cell carcinoma. | World journal of surgical oncology 20120101 |
Transcriptional regulation of hTREX84 in human cancer cells. | PloS one 20120101 |
Combinatorial treatment of DNA and chromatin-modifying drugs cause cell death in human and canine osteosarcoma cell lines. | PloS one 20120101 |
Effect of 5-azacytidine on in vitro biofilm formation of Streptococcus pneumoniae. | Microbial pathogenesis 20120101 |
Azacitidine-induced pneumonitis in a patient with myelodysplastic syndrome: first case report in Japan. | Internal medicine (Tokyo, Japan) 20120101 |
Unlike pancreatic cancer cells pancreatic cancer associated fibroblasts display minimal gene induction after 5-aza-2'-deoxycytidine. | PloS one 20120101 |
Mining gene expression signature for the detection of pre-malignant melanocytes and early melanomas with risk for metastasis. | PloS one 20120101 |
5-aza-2'-deoxycytidine leads to reduced embryo implantation and reduced expression of DNA methyltransferases and essential endometrial genes. | PloS one 20120101 |
Alterations of the WNT7A gene in clear cell renal cell carcinomas. | PloS one 20120101 |
Silencing of glutathione peroxidase 3 through DNA hypermethylation is associated with lymph node metastasis in gastric carcinomas. | PloS one 20120101 |
Acute hypersensitivity of pluripotent testicular cancer-derived embryonal carcinoma to low-dose 5-aza deoxycytidine is associated with global DNA Damage-associated p53 activation, anti-pluripotency and DNA demethylation. | PloS one 20120101 |
MeCP2 controls the expression of RASAL1 in the hepatic fibrosis in rats. | Toxicology 20111218 |
S-Adenosylhomocysteine enhances DNA damage through increased β-amyloid formation and inhibition of the DNA-repair enzyme OGG1b in microglial BV-2 cells. | Toxicology 20111218 |
C(5) modified uracil derivatives showing antiproliferative and erythroid differentiation inducing activities on human chronic myelogenous leukemia K562 cells. | European journal of pharmacology 20111215 |
The secret lives of stem cells: unraveling the molecular basis of stem cell aging. | Cell cycle (Georgetown, Tex.) 20111215 |
5-aza-2'-deoxycytidine enhances susceptibility of renal cell carcinoma to paclitaxel by decreasing LEF1/phospho-β-catenin expression. | Cancer letters 20111208 |
Primary CNS lymphoma other than DLBCL: a descriptive analysis of clinical features and treatment outcomes. | Annals of hematology 20111201 |
Effects of epigenetic-based anti-cancer drugs in leukaemia and multiple myeloma cells. | Cell biology international 20111201 |
DNA methylation regulates the expression of CXCL12 in rheumatoid arthritis synovial fibroblasts. | Genes and immunity 20111201 |
Role of BCL2L10 methylation and TET2 mutations in higher risk myelodysplastic syndromes treated with 5-azacytidine. | Leukemia 20111201 |
The association between non-Hodgkin lymphoma and methylation of p73. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20111201 |
Survival benefits from reduced-intensity conditioning in allogeneic stem cell transplantation for young lower-risk MDS patients without significant comorbidities. | European journal of haematology 20111201 |
Modulation of protein expression levels and DNA methylation status of breast cancer metastasis genes by anthracycline-based chemotherapy and the demethylating agent decitabine. | Cell biochemistry and function 20111201 |
Reversal of epigenetic silencing of AP-2alpha results in increased zinc uptake in DU-145 and LNCaP prostate cancer cells. | Carcinogenesis 20111201 |
Epigenetic regulation of miR-34b and miR-129 expression in gastric cancer. | International journal of cancer 20111201 |
Platelet doubling after the first azacitidine cycle is a promising predictor for response in myelodysplastic syndromes (MDS), chronic myelomonocytic leukaemia (CMML) and acute myeloid leukaemia (AML) patients in the Dutch azacitidine compassionate named patient programme. | British journal of haematology 20111201 |
The seminoma cell line TCam-2 is sensitive to HDAC inhibitor depsipeptide but tolerates various other chemotherapeutic drugs and loss of NANOG expression. | Genes, chromosomes & cancer 20111201 |
Epigenetic regulation of glucose transporter 4 by estrogen receptor β. | Molecular endocrinology (Baltimore, Md.) 20111201 |
DNA methylation and soy phytoestrogens: quantitative study in DU-145 and PC-3 human prostate cancer cell lines. | Epigenomics 20111201 |
What is the optimal induction strategy for older patients? | Best practice & research. Clinical haematology 20111201 |
Evidence of epigenetic regulation of the tumor suppressor gene cluster flanking RASSF1 in breast cancer cell lines. | Epigenetics 20111201 |
[Poliovirus receptor on surface of acute B lymphoid leukemia cells modulated by epigenetic mechanism]. | Zhongguo shi yan xue ye xue za zhi 20111201 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
[Effect of methylation inhibitor on demethylation pattern of the PD-1 gene in promoter region and PD-1 expression in human T lymphocyte cell line]. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20111201 |
Epigenetic regulation of Delta-Like1 controls Notch1 activation in gastric cancer. | Oncotarget 20111201 |
Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer. | Cancer discovery 20111201 |
Epigenetic inactivation of the MIR34B/C in multiple myeloma. | Blood 20111124 |
HDAC inhibitors and decitabine are highly synergistic and associated with unique gene-expression and epigenetic profiles in models of DLBCL. | Blood 20111117 |
Chromatin-modifying drugs induce miRNA-153 expression to suppress Irs-2 in glioblastoma cell lines. | International journal of cancer 20111115 |
CpG methylation at the USF-binding site mediates cell-specific transcription of human ascorbate transporter SVCT2 exon 1a. | The Biochemical journal 20111115 |
Improving T-cell therapy for relapsed EBV-negative Hodgkin lymphoma by targeting upregulated MAGE-A4. | Clinical cancer research : an official journal of the American Association for Cancer Research 20111115 |
MAGE: the spell is broken. | Clinical cancer research : an official journal of the American Association for Cancer Research 20111115 |
Immunotherapy augments the effect of 5-azacytidine on HPV16-associated tumours with different MHC class I-expression status. | British journal of cancer 20111108 |
Reactive oxygen species downregulate catalase expression via methylation of a CpG island in the Oct-1 promoter. | FEBS letters 20111104 |
Amyloid protein-mediated differential DNA methylation status regulates gene expression in Alzheimer's disease model cell line. | Biochemical and biophysical research communications 20111104 |
Expression of tyrosine hydroxylase is epigenetically regulated in neural stem cells. | Biochemical and biophysical research communications 20111104 |
Role of PTEN promoter methylation in tamoxifen-resistant breast cancer cells. | Breast cancer research and treatment 20111101 |
5-Aza-2'-deoxycytidine and interleukin-1 cooperate to regulate matrix metalloproteinase-3 gene expression. | International journal of cancer 20111101 |
Histonedeacetylase inhibitor Oxamflatin increase HIV-1 transcription by inducing histone modification in latently infected cells. | Molecular biology reports 20111101 |
Reactivation of transgene expression by alleviating CpG methylation of the Rous sarcoma virus promoter in transgenic quail cells. | Molecular biotechnology 20111101 |
A 5-aza-2'-deoxycytidine/valproate combination induces cytotoxic T-cell response against mesothelioma. | The European respiratory journal 20111101 |
Epigenetic inactivation of the SFRP1 gene in esophageal squamous cell carcinoma. | Digestive diseases and sciences 20111101 |
Antidepressant-like effect induced by systemic and intra-hippocampal administration of DNA methylation inhibitors. | British journal of pharmacology 20111101 |
p53 independent epigenetic-differentiation treatment in xenotransplant models of acute myeloid leukemia. | Leukemia 20111101 |
Acute myeloid leukemia with mutated nucleophosmin (NPM1): any hope for a targeted therapy? | Blood reviews 20111101 |
Aberrant DNA methylation but not mutation of CITED4 is associated with alteration of HIF-regulated genes in breast cancer. | Breast cancer research and treatment 20111101 |
Azacitidine induces demethylation of p16INK4a and inhibits growth in adult T-cell leukemia/lymphoma. | International journal of molecular medicine 20111101 |
Epigenetics: DNA demethylation promotes skeletal myotube maturation. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20111101 |
γ-radiation induces cellular sensitivity and aberrant methylation in human tumor cell lines. | International journal of radiation biology 20111101 |
Acquired alpha thalassemia myelodyslastic/myeloproliferative syndrome (ATMDS): evolution on hypomethylating agent therapy. | Leukemia research 20111101 |
Impact of the hypomethylating agent 5-azacytidine on dendritic cells function. | Experimental hematology 20111101 |
Histone modifications and methyl-CpG-binding domain protein levels at the TNFSF7 (CD70) promoter in SLE CD4+ T cells. | Lupus 20111101 |
WIF1 is a frequent target for epigenetic silencing in squamous cell carcinoma of the cervix. | Carcinogenesis 20111101 |
The subpopulation of mesenchymal stem cells that differentiate toward cardiomyocytes is cardiac progenitor cells. | Experimental cell research 20111101 |
Expression and immunotherapeutic targeting of the SSX family of cancer-testis antigens in prostate cancer. | Cancer research 20111101 |
Cancer-testis antigen expression and its epigenetic modulation in acute myeloid leukemia. | American journal of hematology 20111101 |
Cytogenetic and molecular abnormalities in myelodysplastic syndrome. | Current molecular medicine 20111101 |
The regulation of MASPIN expression in epithelial ovarian cancer: association with p53 status, and MASPIN promoter methylation: a gynecologic oncology group study. | Gynecologic oncology 20111101 |
Hypomethylation of proximal CpG motif of interleukin-10 promoter regulates its expression in human rheumatoid arthritis. | Acta pharmacologica Sinica 20111101 |
Decitabine, independent of apoptosis, exerts its cytotoxic effects on cell growth in melanoma cells. | Environmental toxicology and pharmacology 20111101 |
Rapid isolation of adipose tissue-derived stem cells by the storage of lipoaspirates. | Yonsei medical journal 20111101 |
Epigenetic stability of repressed states involving the histone variant macroH2A revealed by nuclear transfer to Xenopus oocytes. | Nucleus (Austin, Tex.) 20111101 |
DNA methylation patterns of Brachypodium distachyon chromosomes and their alteration by 5-azacytidine treatment. | Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 20111101 |
5-AZA-2'-deoxycytidine induced demethylation influences N-glycosylation of secreted glycoproteins in ovarian cancer. | Epigenetics 20111101 |
The effect of epigenetic factors on differentiation of pancreatic progenitor cells into insulin-producing cells. | Transplantation proceedings 20111101 |
5-azacytidine reverses drug resistance in bladder cancer cells. | Anticancer research 20111101 |
[Effect of methylation modification on the expression of Cosmc gene in peripheral B lymphocyte of IgA nephropathy patients]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20111101 |
[The clinical research of treatment by decitabine moderate or high-risk myelodysplastic syndrome patients]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20111101 |
5-aza-2'-deoxycytidine activates iron uptake and heme biosynthesis by increasing c-Myc nuclear localization and binding to the E-boxes of transferrin receptor 1 (TfR1) and ferrochelatase (Fech) genes. | The Journal of biological chemistry 20111028 |
Therapy related acute myeloid leukemia with t(10:16): a rare entity. | Hematology reports 20111019 |
Intrathecal 5-azacytidine inhibits global DNA methylation and methyl- CpG-binding protein 2 expression and alleviates neuropathic pain in rats following chronic constriction injury. | Brain research 20111018 |
Analysis of expression and structure of the rat GH-secretagogue/ghrelin receptor (Ghsr) gene: roles of epigenetic modifications in transcriptional regulation. | Molecular and cellular endocrinology 20111015 |
FMR1 CGG repeat lengths mediate different regulation of reporter gene expression in comparative transient and locus specific integration assays. | Gene 20111015 |
[Aberrant methylation of T-cadherin gene in human esophageal carcinoma cells]. | Zhonghua yi xue za zhi 20111011 |
Aberrant methylation of the 3q25 tumor suppressor gene PTX3 in human esophageal squamous cell carcinoma. | World journal of gastroenterology 20111007 |
Molecular predictors of response to decitabine in advanced chronic myelomonocytic leukemia: a phase 2 trial. | Blood 20111006 |
In vitro investigation and biomechanical modeling of the effects of PLF-68 on osteoarthritis in a three-dimensional model. | Biomechanics and modeling in mechanobiology 20111001 |
Aberrant CpG island hypermethylation and down-regulation of Oct-6 mRNA expression in human hepatocellular carcinoma. | Digestive diseases and sciences 20111001 |
Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apoptosis, G2/M arrest, and autophagy. | Cancer 20111001 |
A prospective multicenter observational study of decitabine treatment in Korean patients with myelodysplastic syndrome. | Haematologica 20111001 |
5'-Azacitidine for therapy-related myelodysplastic syndromes after non-Hodgkin lymphoma treatment. | Leukemia research 20111001 |
Epigenetic regulation of alkaline phosphatase in human cells of the osteoblastic lineage. | Bone 20111001 |
Minimal residual disease-directed preemptive treatment with azacitidine in patients with NPM1-mutant acute myeloid leukemia and molecular relapse. | Haematologica 20111001 |
Cautions regarding the fitting and interpretation of survival curves: examples from NICE single technology appraisals of drugs for cancer. | PharmacoEconomics 20111001 |
Combined inhibition of DNA methyltransferase and histone deacetylase restores caspase-8 expression and sensitizes SCLC cells to TRAIL. | Carcinogenesis 20111001 |
Targeting HSP 90 induces apoptosis and inhibits critical survival and proliferation pathways in multiple myeloma. | Molecular cancer therapeutics 20111001 |
Neuronal activity modifies the DNA methylation landscape in the adult brain. | Nature neuroscience 20111001 |
Hematopoietic growth factors in myelodysplastic syndromes. | Seminars in oncology 20111001 |
Treatment of higher-risk myelodysplastic syndrome. | Seminars in oncology 20111001 |
Failure of hypomethylating agent-based therapy in myelodysplastic syndromes. | Seminars in oncology 20111001 |
Epigenetic modifiers exert renal toxicity through induction of p66shc. | Anticancer research 20111001 |
[Novel therapeutics for myelodysplastic syndromes]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20111001 |
Direct lineage conversions: unnatural but useful? | Nature biotechnology 20111001 |
[Silence mechanism of WT1 gene in leukemic cell line U937]. | Zhongguo shi yan xue ye xue za zhi 20111001 |
RNA polymerase II stalling promotes nucleosome occlusion and pTEFb recruitment to drive immortalization by Epstein-Barr virus. | PLoS pathogens 20111001 |
The molecular biology of frog virus 3 and other iridoviruses infecting cold-blooded vertebrates. | Viruses 20111001 |
Epigenomics in hematopoietic transplantation: novel treatment strategies. | Epigenomics 20111001 |
Successful allogeneic stem-cell transplantation in a patient with myelodysplastic syndrome with hemodialysis-dependent end-stage renal disease. | Transplantation 20110927 |
Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate. | Oncogene 20110922 |
Inhibition of p53 represses E-cadherin expression by increasing DNA methyltransferase-1 and promoter methylation in serous borderline ovarian tumor cells. | Oncogene 20110915 |
Evaluating the global CpG methylation status of native DNA utilizing a bipartite split-luciferase sensor. | Analytical chemistry 20110915 |
News on hypomethylating agents: chasing the FOX. | Cell cycle (Georgetown, Tex.) 20110915 |
A pilot study of subcutaneous decitabine in β-thalassemia intermedia. | Blood 20110908 |
Lycopene and apo-10'-lycopenal do not alter DNA methylation of GSTP1 in LNCaP cells. | Biochemical and biophysical research communications 20110902 |
Epigenetic regulation of DNA methyltransferases: DNMT1 and DNMT3B in gliomas. | Journal of neuro-oncology 20110901 |
Hypomethylating agents for the treatment of acute myeloid leukemia in the elderly: for all, none, or which patients? | Cancer 20110901 |
Laser-captured microdissection-microarray analysis of the genes involved in endometrial carcinogenesis: stepwise up-regulation of lipocalin2 expression in normal and neoplastic endometria and its functional relevance. | Human pathology 20110901 |
Epigenetic repolarization of T lymphocytes from chronic lymphocytic leukemia patients using 5-aza-2'-deoxycytidine. | Leukemia research 20110901 |
A sex-chromosome mutation in Silene latifolia. | Sexual plant reproduction 20110901 |
Effect of trichostatin A and 5-Aza-2'-deoxycytidine on transgene reactivation and epigenetic modification in transgenic pig fibroblast cells. | Molecular and cellular biochemistry 20110901 |
Increased PRAME antigen-specific killing of malignant cell lines by low avidity CTL clones, following treatment with 5-Aza-2'-Deoxycytidine. | Cancer immunology, immunotherapy : CII 20110901 |
Phase I and II study of azacitidine in Japanese patients with myelodysplastic syndromes. | Cancer science 20110901 |
MAGE-A1, MAGE-A3, and NY-ESO-1 can be upregulated on neuroblastoma cells to facilitate cytotoxic T lymphocyte-mediated tumor cell killing. | Cancer immunology, immunotherapy : CII 20110901 |
Decreased expression of protease-activated receptor 4 in human gastric cancer. | The international journal of biochemistry & cell biology 20110901 |
The DNA methylome of benign and malignant parathyroid tumors. | Genes, chromosomes & cancer 20110901 |
Transformation-dependent silencing of tumor-selective apoptosis-inducing TRAIL by DNA hypermethylation is antagonized by decitabine. | Molecular cancer therapeutics 20110901 |
Heparan sulfate D-glucosaminyl 3-O-sulfotransferase-3B1, a novel epithelial-mesenchymal transition inducer in pancreatic cancer. | Cancer biology & therapy 20110901 |
Definition of the landscape of promoter DNA hypomethylation in liver cancer. | Cancer research 20110901 |
Identification of mutations conferring 5-azacytidine resistance in bacteriophage Qβ. | Virology 20110901 |
Hypomethylating agents in the treatment of myelodysplastic syndromes and myeloid leukemia. | Current cancer drug targets 20110901 |
Exon 11 skipping of E-cadherin RNA downregulates its expression in head and neck cancer cells. | Molecular cancer therapeutics 20110901 |
Transplantation of induced bone marrow mesenchymal stem cells improves the cardiac function of rabbits with dilated cardiomyopathy via upregulation of vascular endothelial growth factor and its receptors. | Experimental biology and medicine (Maywood, N.J.) 20110901 |
NOR1 is an HSF1- and NRF1-regulated putative tumor suppressor inactivated by promoter hypermethylation in nasopharyngeal carcinoma. | Carcinogenesis 20110901 |
Combination decitabine, arsenic trioxide, and ascorbic acid for the treatment of myelodysplastic syndrome and acute myeloid leukemia: a phase I study. | American journal of hematology 20110901 |
TCF21 and PCDH17 methylation: An innovative panel of biomarkers for a simultaneous detection of urological cancers. | Epigenetics 20110901 |
Dynamics of bivalent chromatin domains upon drug induced reactivation and resilencing in cancer cells. | Epigenetics 20110901 |
Coordinated epigenetic regulation of autophagy and apoptosis. | Cell cycle (Georgetown, Tex.) 20110901 |
Murine gamma-herpesvirus immortalization of fetal liver-derived B cells requires both the viral cyclin D homolog and latency-associated nuclear antigen. | PLoS pathogens 20110901 |
Hypomethylation of the hsa-miR-191 locus causes high expression of hsa-mir-191 and promotes the epithelial-to-mesenchymal transition in hepatocellular carcinoma. | Neoplasia (New York, N.Y.) 20110901 |
Retrotransposon-induced heterochromatin spreading in the mouse revealed by insertional polymorphisms. | PLoS genetics 20110901 |
Complete remission of Waldenström macroglobulinemia with azacitidine and rituximab. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110820 |
Outcome of high-risk myelodysplastic syndrome after azacitidine treatment failure. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110820 |
Phase 1 study of epigenetic priming with decitabine prior to standard induction chemotherapy for patients with AML. | Blood 20110811 |
Cytosine methylation regulates oviposition in the pathogenic blood fluke Schistosoma mansoni. | Nature communications 20110809 |
Identification of methylation profile of HOX genes in extrahepatic cholangiocarcinoma. | World journal of gastroenterology 20110807 |
MicroRNA-193a represses c-kit expression and functions as a methylation-silenced tumor suppressor in acute myeloid leukemia. | Oncogene 20110804 |
Human BM stem cells initiate angiogenesis in human islets in vitro. | Bone marrow transplantation 20110801 |
Promoter hypermethylation of cyclooxygenase-2 gene in esophageal squamous cell carcinoma. | Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20110801 |
Interferon-alpha induces reversible DNA demethylation of the interferon-induced transmembrane protein-3 core promoter in human melanoma cells. | Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20110801 |
Thrice weekly azacitidine does not improve hematological responses in lower-risk myelodysplastic syndromes: a study of the Hoosier Oncology Group. | Leukemia research 20110801 |
DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer. | European journal of cancer (Oxford, England : 1990) 20110801 |
Inhibition of p53-p21 pathway promotes the differentiation of rat bone marrow mesenchymal stem cells into cardiomyocytes. | Molecular and cellular biochemistry 20110801 |
The effects of 5-aza-2'- deoxycytidine and trichostatin A on gene expression and DNA methylation status in cloned bovine blastocysts. | Cellular reprogramming 20110801 |
Delineation of the molecular mechanisms of nucleoside recognition by cytidine deaminase through virtual screening. | ChemMedChem 20110801 |
Use of integrative epigenetic and cytogenetic analyses to identify novel tumor-suppressor genes in malignant melanoma. | Melanoma research 20110801 |
Cytogenetic response is not a prerequisite for clinical response in patients with myelodysplastic syndromes treated with azacitidine. | European journal of haematology 20110801 |
Cellular DNA methylation program during neurulation and its alteration by alcohol exposure. | Birth defects research. Part A, Clinical and molecular teratology 20110801 |
MicroRNA 345, a methylation-sensitive microRNA is involved in cell proliferation and invasion in human colorectal cancer. | Carcinogenesis 20110801 |
The effect of decitabine on megakaryocyte maturation and platelet release. | Thrombosis and haemostasis 20110801 |
The depletion of DNA methyltransferase-1 and the epigenetic effects of 5-aza-2'deoxycytidine (decitabine) are differentially regulated by cell cycle progression. | Epigenetics 20110801 |
Proteasome inhibition in myelodysplastic syndromes and acute myelogenous leukemia cell lines. | Cancer investigation 20110801 |
Methylation of specific CpG sites in the P2 promoter of parathyroid hormone-related protein determines the invasive potential of breast cancer cell lines. | Epigenetics 20110801 |
The application of delivery systems for DNA methyltransferase inhibitors. | BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20110801 |
Hematologic outcomes of myelodysplastic syndromes treatment with hypomethylating agents in community practice. | Clinical lymphoma, myeloma & leukemia 20110801 |
[Hypomethylating agents for the treatment of myelodysplastic syndromes]. | Bulletin du cancer 20110801 |
[Effects of decitabine on biological behavior of U266 cells]. | Zhongguo shi yan xue ye xue za zhi 20110801 |
Downregulation of ARFGEF1 and CAMK2B by promoter hypermethylation in breast cancer cells. | BMB reports 20110801 |
Methylation-associated dysregulation of the suppressor of cytokine signaling-3 gene in multiple myeloma. | Epigenetics 20110801 |
[The effects of pulsed electromagnetic fields on the induction of rat bone marrow mesenchymal stem cells to differentiate into cardiomyocytes-like cells in vitro]. | Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20110801 |
Expression profiling of non-aflatoxigenic Aspergillus parasiticus mutants obtained by 5-azacytosine treatment or serial mycelial transfer. | Toxins 20110801 |
[Differentiation of porcine amniotic fluid stem cells into the beating cardiomyocytes]. | Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20110801 |
[Mechanism of loss of human esophageal cancer-related gene 4 (ECRG4) gene expression in esophageal squamous cell carcinoma cell line EC9706]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20110801 |
Epigenetic regulation of prostate cancer. | Clinical epigenetics 20110801 |
The biological basis and clinical significance of hormonal imprinting, an epigenetic process. | Clinical epigenetics 20110801 |
Epigenetic abnormalities in myeloproliferative neoplasms: a target for novel therapeutic strategies. | Clinical epigenetics 20110801 |
Epigenetic management of major psychosis. | Clinical epigenetics 20110801 |
Long interspersed nuclear element-1 hypomethylation in cancer: biology and clinical applications. | Clinical epigenetics 20110801 |
Treatment of poor-risk myelodysplastic syndromes and acute myeloid leukemia with a combination of 5-azacytidine and valproic acid. | Clinical epigenetics 20110801 |
Epigenetic approaches in stem cell transplantation. | Clinical epigenetics 20110801 |
Aberrant DNA hypermethylation of the ITIH5 tumor suppressor gene in acute myeloid leukemia. | Clinical epigenetics 20110801 |
Evolutional and clinical implications of the epigenetic regulation of protein glycosylation. | Clinical epigenetics 20110801 |
The role of promoter methylation in Epstein-Barr virus (EBV) microRNA expression in EBV-infected B cell lines. | Experimental & molecular medicine 20110731 |
Suppression of WIF-1 through promoter hypermethylation causes accelerated proliferation of the aryl hydrocarbon receptor (AHR) overexpressing MCF10AT1 breast cancer cells. | Toxicology 20110729 |
Nongenetic reprogramming of a fungal highly reducing polyketide synthase. | Journal of the American Chemical Society 20110720 |
Mammalian Gcm genes induce Hes5 expression by active DNA demethylation and induce neural stem cells. | Nature neuroscience 20110717 |
Epigenetic mechanisms for silencing glutathione S-transferase m2 expression by hypermethylated specificity protein 1 binding in lung cancer. | Cancer 20110715 |
MicroRNA-146a downregulates NFκB activity via targeting TRAF6 and functions as a tumor suppressor having strong prognostic implications in NK/T cell lymphoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110715 |
Azacitidine-resistant SKM1 myeloid cells are defective for AZA-induced mitochondrial apoptosis and autophagy. | Cell cycle (Georgetown, Tex.) 20110715 |
Hypomethylating agents reactivate FOXO3A in acute myeloid leukemia. | Cell cycle (Georgetown, Tex.) 20110715 |
Effect of 5-azacytidine: evidence for alteration of the multipotent ability of mesenchymal stem cells. | Stem cells and development 20110701 |
Pattern of hypomethylating agents use among elderly patients with myelodysplastic syndromes. | Leukemia research 20110701 |
Response to 5-azacytidine in a patient with relapsed Hodgkin Lymphoma and a therapy-related myelodysplastic syndrome. | British journal of haematology 20110701 |
A novel, efficient method to derive bovine and mouse embryonic stem cells with in vivo differentiation potential by treatment with 5-azacytidine. | Theriogenology 20110701 |
Recurrent DNMT3A mutations in patients with myelodysplastic syndromes. | Leukemia 20110701 |
Changes in the levels of DNA methylation in testis and liver of SD rats neonatally exposed to 5-aza-2'-deoxycytidine and cadmium. | Journal of applied toxicology : JAT 20110701 |
The in vivo induction of sister chromatid exchange by the demethylating agent 5-aza-2'-deoxycytidine. | Mutagenesis 20110701 |
Prognostic significance of monosomal karyotype in higher risk myelodysplastic syndrome treated with azacitidine. | Leukemia 20110701 |
DNMT3B gene amplification predicts resistance to DNA demethylating drugs. | Genes, chromosomes & cancer 20110701 |
Methylation silencing of angiopoietin-like 4 in rat and human mammary carcinomas. | Cancer science 20110701 |
Impact of TET2 mutations on response rate to azacitidine in myelodysplastic syndromes and low blast count acute myeloid leukemias. | Leukemia 20110701 |
Mitochondria determine the differentiation potential of cardiac mesoangioblasts. | Stem cells (Dayton, Ohio) 20110701 |
Simultaneous inhibition of DNA methyltransferase and histone deacetylase induces p53-independent apoptosis via down-regulation of Mcl-1 in acute myelogenous leukemia cells. | Leukemia research 20110701 |
Integrated, genome-wide screening for hypomethylated oncogenes in salivary gland adenoid cystic carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110701 |
EFEMP1 as a novel DNA methylation marker for prostate cancer: array-based DNA methylation and expression profiling. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110701 |
Loss of special AT-rich binding protein 1 expression is a marker of poor survival in lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110701 |
The Levels of H11/HspB8 DNA methylation in human melanoma tissues and xenografts are a critical molecular marker for 5-Aza-2'-deoxycytidine therapy. | Cancer investigation 20110701 |
[High glucose induce the demethylation of CTGF promoter and gene expression]. | Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20110701 |
Antiproliferation and redifferentiation in thyroid cancer cell lines by polyphenol phytochemicals. | Journal of Korean medical science 20110701 |
[Epigenetic therapy in myelodysplastic syndromes]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20110701 |
Mesoangioblasts of inclusion-body myositis: a twofold tool to study pathogenic mechanisms and enhance defective muscle regeneration. | Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology 20110701 |
[Treatment of two chronic myelomonocytic leukemia patients with Decitabine]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110701 |
Silencing of BNIP3 results from promoter methylation by DNA methyltransferase 1 induced by the mitogen-activated protein kinase pathway. | Molecules and cells 20110630 |
Protection of bone marrow-derived CD45+/CD34-/lin- stromal cells with immunosuppressant activity against ischemia/reperfusion injury in rats. | The Chinese journal of physiology 20110630 |
Phase I study of oral azacitidine in myelodysplastic syndromes, chronic myelomonocytic leukemia, and acute myeloid leukemia. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110620 |
Azacytidine impairs NK cell reactivity while decitabine augments NK cell responsiveness toward stimulation. | International journal of cancer 20110615 |
Characterizing DNA methyltransferases with an ultrasensitive luciferase-linked continuous assay. | Analytical chemistry 20110615 |
Activity of azacitidine in chronic myelomonocytic leukemia. | Cancer 20110615 |
Continued azacitidine therapy beyond time of first response improves quality of response in patients with higher-risk myelodysplastic syndromes. | Cancer 20110615 |
Thrombomodulin is silenced in malignant mesothelioma by a poly(ADP-ribose) polymerase-1-mediated epigenetic mechanism. | The Journal of biological chemistry 20110603 |
The autoimmune manifestations associated with myelodysplastic syndrome respond to 5-azacytidine: a report on three cases. | British journal of haematology 20110601 |
Epigenetic inactivation of calcium-sensing receptor in colorectal carcinogenesis. | Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20110601 |
Expression of the human cancer/testis antigen NY-SAR-35 is activated by CpG island hypomethylation. | Biotechnology letters 20110601 |
Histone deacetylase inhibitors upregulate Rap1GAP and inhibit Rap activity in thyroid tumor cells. | Endocrine-related cancer 20110601 |
Clinical significance of expression of Hint1 and potential epigenetic mechanism in gastric cancer. | International journal of oncology 20110601 |
A demethylating agent enhances chemosensitivity to vinblastine in a xenograft model of renal cell carcinoma. | International journal of oncology 20110601 |
Protein inhibitor of activated STAT3 expression in lung cancer. | Molecular oncology 20110601 |
Ultra-performance liquid chromatography/tandem mass spectrometry for accurate quantification of global DNA methylation in human sperms. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110601 |
Transcription intermediary factor 1γ is a tumor suppressor in mouse and human chronic myelomonocytic leukemia. | The Journal of clinical investigation 20110601 |
Use of hypomethylating agents and associated care in patients with myelodysplastic syndromes: a claims database study. | Current medical research and opinion 20110601 |
2´-deoxy-5,6-dihydro-5-azacytidine - a less toxic alternative of 2´-deoxy-5-azacytidine: a comparative study of hypomethylating potential. | Epigenetics 20110601 |
Adverse effects of azacitidine: onset, duration, and treatment. | Advances in therapy 20110601 |
Azacitidine adverse effects in patients with myelodysplastic syndromes. | Advances in therapy 20110601 |
Epigenetically silenced miR-34b/c as a novel faecal-based screening marker for colorectal cancer. | British journal of cancer 20110524 |
Low-dose decitabine versus best supportive care in elderly patients with intermediate- or high-risk myelodysplastic syndrome (MDS) ineligible for intensive chemotherapy: final results of the randomized phase III study of the European Organisation for Research and Treatment of Cancer Leukemia Group and the German MDS Study Group. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110520 |
Genome-wide DNA methylation analysis of neuroblastic tumors reveals clinically relevant epigenetic events and large-scale epigenomic alterations localized to telomeric regions. | International journal of cancer 20110515 |
Acute myocarditis induced by hypomethylating agents. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110510 |
5-azacytidine as salvage treatment in relapsed myeloid tumors after allogeneic bone marrow transplantation. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110501 |
Epigenetic modulation of MAGE-A3 antigen expression in multiple myeloma following treatment with the demethylation agent 5-azacitidine and the histone deacetlyase inhibitor MGCD0103. | Cytotherapy 20110501 |
Treating myelodysplastic syndrome improves an accompanying autoimmune disease along with a reduction in regulatory T-cells. | Leukemia research 20110501 |
The anti-leukemic effect and molecular mechanisms of novel hydroxamate and benzamide histone deacetylase inhibitors with 5-aza-cytidine. | International journal of oncology 20110501 |
DNA methylation restricts spontaneous multi-lineage differentiation of mesenchymal progenitor cells, but is stable during growth factor-induced terminal differentiation. | Biochimica et biophysica acta 20110501 |
Epigenetic modulation enhances the therapeutic effect of anti-IL-13R(alpha)2 antibody in human mesothelioma xenografts. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110501 |
Hypermethylation-modulated down-regulation of CDH1 expression contributes to the progression of esophageal cancer. | International journal of molecular medicine 20110501 |
Azacitidine combined with gemtuzumab ozogamicin in patients with relapsed/refractory acute myeloid leukemia. | Leukemia & lymphoma 20110501 |
Epigenetics and its implications for ecotoxicology. | Ecotoxicology (London, England) 20110501 |
Aberrant promoter methylation in overexpression of CITED1 in papillary thyroid cancer. | Thyroid : official journal of the American Thyroid Association 20110501 |
In sickness and in health: the role of methyl-CpG binding protein 2 in the central nervous system. | The European journal of neuroscience 20110501 |
Azacitidine: a new medication associated with Sweet syndrome. | Journal of the American Academy of Dermatology 20110501 |
Modulation of the poliovirus receptor expression in malignant lymphocytes by epigenetic alterations. | Journal of immunotherapy (Hagerstown, Md. : 1997) 20110501 |
Multipotent mesenchymal stromal cells express FoxP3: a marker for the immunosuppressive capacity? | Journal of immunotherapy (Hagerstown, Md. : 1997) 20110501 |
Pharmacokinetic evaluation of decitabine for the treatment of leukemia. | Expert opinion on drug metabolism & toxicology 20110501 |
Mouse models of graft-versus-host disease: advances and limitations. | Disease models & mechanisms 20110501 |
The glycan-binding protein galectin-1 controls survival of epithelial cells along the crypt-villus axis of small intestine. | Cell death & disease 20110501 |
[Promoter methylation status of hPer3 gene in AML patients and the in vitro effect of decitabine on the status]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110501 |
[Reversal effect of 5-Aza-dc on cisplatin-resistance in human NSCLC cells in vitro]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20110501 |
Effective myotube formation in human adipose tissue-derived stem cells expressing dystrophin and myosin heavy chain by cellular fusion with mouse C2C12 myoblasts. | Biochemical and biophysical research communications 20110429 |
Wnt antagonist DKK1 acts as a tumor suppressor gene that induces apoptosis and inhibits proliferation in human renal cell carcinoma. | International journal of cancer 20110415 |
Aberrant methylation of the X-linked ribosomal S6 kinase RPS6KA6 (RSK4) in endometrial cancers. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110415 |
Phase 1b-2a study to reverse platinum resistance through use of a hypomethylating agent, azacitidine, in patients with platinum-resistant or platinum-refractory epithelial ovarian cancer. | Cancer 20110415 |
Hypermethylation of the progesterone receptor A in constitutive antiprogestin-resistant mouse mammary carcinomas. | Breast cancer research and treatment 20110401 |
Histone methylation is a critical regulator of the abnormal expression of POU5F1 and RASSF1A in testis cancer cell lines. | International journal of andrology 20110401 |
5-Azacytidine in myelodysplastic syndromes: a clinical practice guideline. | Cancer treatment reviews 20110401 |
Decreased incidence of febrile episodes with antibiotic prophylaxis in the treatment of decitabine for myelodysplastic syndrome. | Leukemia research 20110401 |
Aberrant methylation of the RIZ1 gene in myelodysplastic syndrome and acute myeloid leukemia. | Leukemia research 20110401 |
Gene expression profiling of myelodysplastic CD34+ hematopoietic stem cells treated in vitro with decitabine. | Leukemia research 20110401 |
Hydralazine and magnesium valproate as epigenetic treatment for myelodysplastic syndrome. Preliminary results of a phase-II trial. | Annals of hematology 20110401 |
Epigenetic modification involved in benzene-induced apoptosis through regulating apoptosis-related genes expression. | Cell biology international 20110401 |
Decitabine-induced apoptosis is derived by Puma and Noxa induction in chronic myeloid leukemia cell line as well as in PBL and is potentiated by SAHA. | Molecular and cellular biochemistry 20110401 |
5-Aza-2'-deoxycytidine increases sialyl Lewis X on MUC1 by stimulating β-galactoside:α2,3-sialyltransferase 6 gene. | The international journal of biochemistry & cell biology 20110401 |
Reduction of Fas/CD95 promoter methylation, upregulation of Fas protein, and enhancement of sensitivity to apoptosis in cutaneous T-cell lymphoma. | Archives of dermatology 20110401 |
Modulation of matrix metalloproteinase activity in human thyroid cancer cell lines using demethylating agents and histone deacetylase inhibitors. | Surgery 20110401 |
(-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells. | Carcinogenesis 20110401 |
Differentiation induction of cardiac c-kit positive cells from rat heart into sinus node-like cells by 5-azacytidine. | Tissue & cell 20110401 |
GPR54 is a target for suppression of metastasis in endometrial cancer. | Molecular cancer therapeutics 20110401 |
5'-azacitidine in myelodysplastic syndromes with inversion of chromosome 3. | Leukemia 20110401 |
Epigenetic gene silencing is a novel mechanism involved in delayed manifestation of radiation-induced genomic instability in mammalian cells. | Radiation research 20110401 |
Quantitative assessment of AKAP12 promoter methylation in human prostate cancer using methylation-sensitive high-resolution melting: correlation with Gleason score. | Urology 20110401 |
Interleukin-6 expression was regulated by epigenetic mechanisms in response to influenza virus infection or dsRNA treatment. | Molecular immunology 20110401 |
Epigenetic regulation in myelodysplastic syndromes: implications for therapy. | Expert opinion on investigational drugs 20110401 |
Stability of azacitidine suspensions. | The Annals of pharmacotherapy 20110401 |
Abnormal methylation of histone deacetylase genes: implications on etiology and epigenetic therapy of astrocytomas. | Anticancer research 20110401 |
NICE guidance on azacitidine for the treatment of myelodysplastic syndromes, chronic myelomonocytic leukaemia, and acute myeloid leukaemia. | The Lancet. Oncology 20110401 |
Down-regulation of NDRG2 gene expression in human colorectal cancer involves promoter methylation and microRNA-650. | Biochemical and biophysical research communications 20110325 |
Hypermethylation of CpG islands and shores around specific microRNAs and mirtrons is associated with the phenotype and presence of bladder cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110315 |
Production of cloned calves by combination treatment of both donor cells and early cloned embryos with 5-aza-2/-deoxycytidine and trichostatin A. | Theriogenology 20110315 |
Phase I study of decitabine in combination with vorinostat in patients with advanced solid tumors and non-Hodgkin's lymphomas. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110315 |
MBD2 contributes to developmental silencing of the human ε-globin gene. | Blood cells, molecules & diseases 20110315 |
MiR-218 suppresses nasopharyngeal cancer progression through downregulation of survivin and the SLIT2-ROBO1 pathway. | Cancer research 20110315 |
DNA methylation-dependent regulation of TrkA, TrkB, and TrkC genes in human hepatocellular carcinoma. | Biochemical and biophysical research communications 20110304 |
5-azacytidine, a chemotherapeutic drug, induces TRAIL-mediated apoptosis in mouse thymocytes in vivo. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20110301 |
MicroRNA let-7 suppresses nasopharyngeal carcinoma cells proliferation through downregulating c-Myc expression. | Journal of cancer research and clinical oncology 20110301 |
In vitro cardiomyogenic potential of human amniotic fluid stem cells. | Journal of tissue engineering and regenerative medicine 20110301 |
Identification of GPX3 epigenetically silenced by CpG methylation in human esophageal squamous cell carcinoma. | Digestive diseases and sciences 20110301 |
Restoring the functional immunogenicity of chronic lymphocytic leukemia using epigenetic modifiers. | Leukemia research 20110301 |
Chronic exposure to cigarette smoke condensate in vitro induces epithelial to mesenchymal transition-like changes in human bronchial epithelial cells, BEAS-2B. | Toxicology in vitro : an international journal published in association with BIBRA 20110301 |
An in vivo rat model to study epigenetic control of cell invasion. | Medical hypotheses 20110301 |
Regulation of KEAP1 expression by promoter methylation in malignant gliomas and association with patient's outcome. | Epigenetics 20110301 |
DNA hypomethylation causes bile duct defects in zebrafish and is a distinguishing feature of infantile biliary atresia. | Hepatology (Baltimore, Md.) 20110301 |
New nucleoside analogs for patients with hematological malignancies. | Expert opinion on investigational drugs 20110301 |
Novel agents for the treatment of acute myeloid leukemia in the older patient. | Journal of the National Comprehensive Cancer Network : JNCCN 20110301 |
Hypomethylating agents for urologic cancers. | Future oncology (London, England) 20110301 |
Treatment of myelodysplastic syndromes in elderly patients. | Advances in therapy 20110301 |
Azacytidine for the treatment of myelodysplastic syndromes in the elderly. | Advances in therapy 20110301 |
Azacitidine for the treatment of patients with acute myeloid leukemia with 20%-30% blasts and multilineage dysplasia. | Advances in therapy 20110301 |
Acute myeloblastic leukemia. | Advances in therapy 20110301 |
Cardiomyocyte marker expression in a human lymphocyte cell line using mouse cardiomyocyte extract. | Human cell 20110301 |
Epigenetics in cancer: what's the future? | Oncology (Williston Park, N.Y.) 20110301 |
Epigenetic up-regulation of leukemia inhibitory factor (LIF) gene during the progression to breast cancer. | Molecules and cells 20110227 |
Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of DNA methyltransferases 1 and 3a. | Toxicology and applied pharmacology 20110215 |
Noncytotoxic differentiation treatment of renal cell cancer. | Cancer research 20110215 |
Hypomethylating agents and other novel strategies in myelodysplastic syndromes. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110210 |
Irradiation, cisplatin, and 5-azacytidine upregulate cytomegalovirus promoter in tumors and muscles: implementation of non-invasive fluorescence imaging. | Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20110201 |
Functional and epigenetic characterization of the KRT19 gene in renal cell neoplasms. | DNA and cell biology 20110201 |
DNA methyltransferase inhibition may limit cancer cell growth by disrupting ribosome biogenesis. | Epigenetics 20110201 |
Fused-core silica column ultra-performance liquid chromatography-ion trap tandem mass spectrometry for determination of global DNA methylation status. | Analytical biochemistry 20110201 |
Mutation analysis of HIF prolyl hydroxylases (PHD/EGLN) in individuals with features of phaeochromocytoma and renal cell carcinoma susceptibility. | Endocrine-related cancer 20110201 |
Effects of specific DNMT gene depletion on cancer cell transformation and breast cancer cell invasion; toward selective DNMT inhibitors. | Carcinogenesis 20110201 |
Sustained exposure to the DNA demethylating agent, 2'-deoxy-5-azacytidine, leads to apoptotic cell death in chronic myeloid leukemia by promoting differentiation, senescence, and autophagy. | Biochemical pharmacology 20110201 |
Dual antitumour effect of 5-azacytidine by inducing a breakdown of resistance-mediating factors and epigenetic modulation. | Gut 20110201 |
Synergistic induction of PI-PLCβ1 signaling by azacitidine and valproic acid in high-risk myelodysplastic syndromes. | Leukemia 20110201 |
Successful resolution of acute myelogenous leukemia-associated hemophagocytic lymphohistiocytosis with decitabine. | Leukemia & lymphoma 20110201 |
Differential regulation of the p73 cistrome by mammalian target of rapamycin reveals transcriptional programs of mesenchymal differentiation and tumorigenesis. | Proceedings of the National Academy of Sciences of the United States of America 20110201 |
Levels of miR-29b do not predict for response in patients with acute myelogenous leukemia treated with the combination of 5-azacytidine, valproic acid, and ATRA. | American journal of hematology 20110201 |
Aberrant methylation frequency of TNFRSF10C promoter in pancreatic cancer cell lines. | Hepatobiliary & pancreatic diseases international : HBPD INT 20110201 |
Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation. | Arthritis and rheumatism 20110201 |
Expression of hypoxic marker CA IX is regulated by site-specific DNA methylation and is associated with the histology of gastric cancer. | The American journal of pathology 20110201 |
DNA methylation suppresses expression of the urea cycle enzyme carbamoyl phosphate synthetase 1 (CPS1) in human hepatocellular carcinoma. | The American journal of pathology 20110201 |
DNA methylation changes following 5-azacitidine treatment in patients with myelodysplastic syndrome. | Journal of Korean medical science 20110201 |
Azacitidine. Poor-prognosis myelodysplasia: promising, but more data needed. | Prescrire international 20110201 |
Treatment with 5-azacytidine accelerates acute promyelocytic leukemia leukemogenesis in a transgenic mouse model. | Genes & cancer 20110201 |
Silence of HIN-1 expression through methylation of its gene promoter in gastric cancer. | World journal of gastroenterology 20110128 |
High IGSF4 expression in pediatric M5 acute myeloid leukemia with t(9;11)(p22;q23). | Blood 20110120 |
Effects of MEK and DNMT inhibitors on arsenic-treated human uroepithelial cells in relation to Cyclin-D1 and p16. | Toxicology letters 20110115 |
Combination therapy with vidaza and entinostat suppresses tumor growth and reprograms the epigenome in an orthotopic lung cancer model. | Cancer research 20110115 |
Down-regulation of VEZT gene expression in human gastric cancer involves promoter methylation and miR-43c. | Biochemical and biophysical research communications 20110114 |
Prognostic factors for response and overall survival in 282 patients with higher-risk myelodysplastic syndromes treated with azacitidine. | Blood 20110113 |
Aberrantly silenced promoters retain a persistent memory of the silenced state after long-term reactivation. | Mutation research 20110110 |
Successive detection of insulin-like growth factor-II bound to receptors on a living cell surface using an AFM. | Journal of molecular recognition : JMR 20110101 |
Azacitidine favorably modulates PSA kinetics correlating with plasma DNA LINE-1 hypomethylation in men with chemonaïve castration-resistant prostate cancer. | Urologic oncology 20110101 |
3-Deazauridine enhances the antileukemic action of 5-aza-2'-deoxycytidine and targets drug-resistance due to deficiency in deoxycytidine kinase. | Leukemia research 20110101 |
Azacytidine as a novel agent in the treatment of acute lymphoblastic leukemia. | Leukemia & lymphoma 20110101 |
Reduced methyl-CpG protein binding contributing to miR-184 expression in umbilical cord blood CD4+ T-cells. | Leukemia 20110101 |
Epigenetic silencing of somatostatin in gastric cancer. | Digestive diseases and sciences 20110101 |
Hypomethylating agents in acute lymphoblastic leukemia: untapped potential? | Leukemia & lymphoma 20110101 |
Epigenetic regulation of microRNA expression in cancer. | Methods in molecular biology (Clifton, N.J.) 20110101 |
Epigenetic regulation on the 5'-proximal CpG island of human porcine endogenous retrovirus subgroup A receptor 2/GPR172B. | Microbes and infection 20110101 |
Epigenetic modifiers influence lineage commitment of human bone marrow stromal cells: Differential effects of 5-aza-deoxycytidine and trichostatin A. | Differentiation; research in biological diversity 20110101 |
Demethylation of E-cadherin gene in nasopharyngeal carcinoma could serve as a potential therapeutic strategy. | Journal of biochemistry 20110101 |
Demonstration of additional benefit in adding lenalidomide to azacitidine in patients with higher-risk myelodysplastic syndromes. | American journal of hematology 20110101 |
Premature senescence induced by DNA demethylating agent (Decitabine) as therapeutic option for malignant pleural mesothelioma. | Lung cancer (Amsterdam, Netherlands) 20110101 |
FISH in analysis of gamma ray-induced micronuclei formation in barley. | Journal of applied genetics 20110101 |
Out of Africa and into epigenetics: discovering reprogramming drugs. | Nature cell biology 20110101 |
Novel and emerging drugs for acute myeloid leukemia: pharmacology and therapeutic activity. | Current medicinal chemistry 20110101 |
Histone deacetylase inhibitors in the treatment of hematological malignancies and solid tumors. | Journal of biomedicine & biotechnology 20110101 |
5-azacytidine enhances proliferation in transplanted rat fetal epiglottis. | Frontiers in bioscience (Elite edition) 20110101 |
Identification of novel DNA methylation inhibitors via a two-component reporter gene system. | Journal of biomedical science 20110101 |
NCCN Clinical Practice Guidelines in Oncology: myelodysplastic syndromes. | Journal of the National Comprehensive Cancer Network : JNCCN 20110101 |
Identification of four potential epigenetic modulators from the NCI structural diversity library using a cell-based assay. | Journal of biomedicine & biotechnology 20110101 |
Re-expression of ARHI (DIRAS3) induces autophagy in breast cancer cells and enhances the inhibitory effect of paclitaxel. | BMC cancer 20110101 |
An engineered cardiac reporter cell line identifies human embryonic stem cell-derived myocardial precursors. | PloS one 20110101 |
Cardiogenol C can induce Mouse Hair Bulge Progenitor Cells to Transdifferentiate into Cardiomyocyte-like Cells. | Proteome science 20110101 |
Possible existence of lysosome-like organella within mitochondria and its role in mitochondrial quality control. | PloS one 20110101 |
Mutation of HIV-1 genomes in a clinical population treated with the mutagenic nucleoside KP1461. | PloS one 20110101 |
Intervention, integration and translation in obesity research: Genetic, developmental and metaorganismal approaches. | Philosophy, ethics, and humanities in medicine : PEHM 20110101 |
Quantitative analysis of DNA methylation at all human imprinted regions reveals preservation of epigenetic stability in adult somatic tissue. | Epigenetics & chromatin 20110101 |
Genome-wide analysis of transcriptional reprogramming in mouse models of acute myeloid leukaemia. | PloS one 20110101 |
Abiotic stress and induced DNA hypomethylation cause interphase chromatin structural changes in rice rDNA loci. | Cytogenetic and genome research 20110101 |
The role of HDACs inhibitors in childhood and adolescence acute leukemias. | Journal of biomedicine & biotechnology 20110101 |
Aberrant methylation of Polo-like kinase CpG islands in Plk4 heterozygous mice. | BMC cancer 20110101 |
Involvement of promoter methylation in the regulation of Pregnane X receptor in colon cancer cells. | BMC cancer 20110101 |
Pretreatment of rat bone marrow mesenchymal stem cells with a combination of hypergravity and 5-azacytidine enhances therapeutic efficacy for myocardial infarction. | Biotechnology progress 20110101 |
Transcriptional repressive H3K9 and H3K27 methylations contribute to DNMT1-mediated DNA methylation recovery. | PloS one 20110101 |
Dermal fibroblasts display similar phenotypic and differentiation capacity to fat-derived mesenchymal stem cells, but differ in anti-inflammatory and angiogenic potential. | Vascular cell 20110101 |
Inhibition of histone deacetylases 1 and 6 enhances cytarabine-induced apoptosis in pediatric acute myeloid leukemia cells. | PloS one 20110101 |
Functional and sequence analysis of human neuroglobin gene promoter region. | Biochimica et biophysica acta 20110101 |
Lentiviral vector mediated modification of mesenchymal stem cells & enhanced survival in an in vitro model of ischaemia. | Stem cell research & therapy 20110101 |
Induction of cyclooxygenase-2 expression by hepatitis B virus depends on demethylation-associated recruitment of transcription factors to the promoter. | Virology journal 20110101 |
Azacytidine and decitabine induce gene-specific and non-random DNA demethylation in human cancer cell lines. | PloS one 20110101 |
Genome-wide assessment of imprinted expression in human cells. | Genome biology 20110101 |
[The role of promoter CpG islands methylation of leptin gene in osteoarthritis]. | Zhonghua nei ke za zhi 20110101 |
Adipose-derived stem cells stimulate regeneration of peripheral nerves: BDNF secreted by these cells promotes nerve healing and axon growth de novo. | PloS one 20110101 |
[Progress in research on DNA methylation and laryngeal carcinoma]. | Zhonghua bing li xue za zhi = Chinese journal of pathology 20110101 |
Proximity ligation in situ assay for monitoring the global DNA methylation in cells. | BMC biotechnology 20110101 |
[Study of RASSF1A expression and promoter demethylation in Hep-2 cell line]. | Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 20110101 |
A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability. | PloS one 20110101 |
Retinoic acid induces HL-60 cell differentiation via the upregulation of miR-663. | Journal of hematology & oncology 20110101 |
Epigenetic regulation of cancer-associated genes in ovarian cancer. | International journal of molecular sciences 20110101 |
Epigenetic regulation of satellite cell activation during muscle regeneration. | Stem cell research & therapy 20110101 |
Epigenetic inactivation of the miR-124-1 in haematological malignancies. | PloS one 20110101 |
CpG island methylation in colorectal cancer: past, present and future. | Pathology research international 20110101 |
Human Chondrosarcoma Cells Acquire an Epithelial-Like Gene Expression Pattern via an Epigenetic Switch: Evidence for Mesenchymal-Epithelial Transition during Sarcomagenesis. | Sarcoma 20110101 |
DNA methyltransferase controls stem cell aging by regulating BMI1 and EZH2 through microRNAs. | PloS one 20110101 |
Cardiac differentiation of pluripotent stem cells. | Stem cells international 20110101 |
Enhancer of zeste homolog 2 (EZH2) in pediatric soft tissue sarcomas: first implications. | BMC medicine 20110101 |
5-azacytidine in chronic myelomonocytic leukemia: case report and review of literature. | Mediterranean journal of hematology and infectious diseases 20110101 |
Interpreting clinical assays for histone deacetylase inhibitors. | Cancer management and research 20110101 |
SLIT2 is epigenetically silenced in ovarian cancers and suppresses growth when activated. | Asian Pacific journal of cancer prevention : APJCP 20110101 |
Myelodysplastic syndrome and histone deacetylase inhibitors: 'to be or not to be acetylated'? | Journal of biomedicine & biotechnology 20110101 |
Allele-specific, age-dependent and BMI-associated DNA methylation of human MCHR1. | PloS one 20110101 |
Aberrant methylation of N-methyl-D-aspartate receptor type 2B (NMDAR2B) in non-small cell carcinoma. | BMC cancer 20110101 |
SIP1 is downregulated in hepatocellular carcinoma by promoter hypermethylation. | BMC cancer 20110101 |
Epigenetic changes in cancer. | F1000 biology reports 20110101 |
Gain of DNA methylation is enhanced in the absence of CTCF at the human retinoblastoma gene promoter. | BMC cancer 20110101 |
Changes in global gene expression in response to chemical and genetic perturbation of chromatin structure. | PloS one 20110101 |
Integrative DNA methylation and gene expression analyses identify DNA packaging and epigenetic regulatory genes associated with low motility sperm. | PloS one 20110101 |
Expression analysis of genes involved in epigenetic regulation and apoptosis in human malignant haematopoietic cell lines treated with 5-azacytidine. | Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20110101 |
Molecular carcinogenesis of hepatocellular carcinoma and intrahepatic cholangiocarcinoma: one step closer to personalized medicine? | Cell & bioscience 20110101 |
Isolation of fidelity variants of RNA viruses and characterization of virus mutation frequency. | Journal of visualized experiments : JoVE 20110101 |
Transformation of human mesenchymal cells and skin fibroblasts into hematopoietic cells. | PloS one 20110101 |
Vitamin A and retinoid derivatives for lung cancer: a systematic review and meta analysis. | PloS one 20110101 |
Expression of MAGE-C1/CT7 and MAGE-C2/CT10 predicts lymph node metastasis in melanoma patients. | PloS one 20110101 |
Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis. | Clinical and experimental gastroenterology 20110101 |
Aberrant DNA methylation is associated with disease progression, resistance to imatinib and shortened survival in chronic myelogenous leukemia. | PloS one 20110101 |
Therapeutic strategies to enhance the anticancer efficacy of histone deacetylase inhibitors. | Journal of biomedicine & biotechnology 20110101 |
Involvement of phosphatases in proliferation, maturation, and hemoglobinization of developing erythroid cells. | Journal of signal transduction 20110101 |
Improvement of cardiac function in mouse myocardial infarction after transplantation of epigenetically-modified bone marrow progenitor cells. | PloS one 20110101 |
Stem Cell Therapy in Acute Myocardial Infarction: A Pot of Gold or Pandora's Box. | Stem cells international 20110101 |
Cellular Reprogramming toward the Erythroid Lineage. | International journal of cell biology 20110101 |
Trichostatin A selectively suppresses the cold-induced transcription of the ZmDREB1 gene in maize. | PloS one 20110101 |
Location-specific epigenetic regulation of the metallothionein 3 gene in esophageal adenocarcinomas. | PloS one 20110101 |
Azacitidine. | Report on carcinogens : carcinogen profiles 20110101 |
Long term transcriptional reactivation of epigenetically silenced genes in colorectal cancer cells requires DNA hypomethylation and histone acetylation. | PloS one 20110101 |
Methylation-associated down-regulation of RASSF1A and up-regulation of RASSF1C in pancreatic endocrine tumors. | BMC cancer 20110101 |
Epigenetic therapy for breast cancer. | International journal of molecular sciences 20110101 |
DNA demethylation is superior to histone acetylation for reactivating cancer-associated genes in ovarian cancer cells. | Molecular medicine reports 20110101 |
Gene network inference and biochemical assessment delineates GPCR pathways and CREB targets in small intestinal neuroendocrine neoplasia. | PloS one 20110101 |
Mechanisms of resistance to decitabine in the myelodysplastic syndrome. | PloS one 20110101 |
DNA methylation of SPARC and chronic low back pain. | Molecular pain 20110101 |
The Ethanol Extract of Fructus trichosanthis Promotes Fetal Hemoglobin Production via p38 MAPK Activation and ERK Inactivation in K562 Cells. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
Efficient non-viral reprogramming of myoblasts to stemness with a single small molecule to generate cardiac progenitor cells. | PloS one 20110101 |
Effects of the demethylating agent, 5-azacytidine, on expression of the kallikrein-kinin genes in carcinoma cells of the lung and pleura. | Pathology research international 20110101 |
DNA demethylation in PD-1 gene promoter induced by 5-azacytidine activates PD-1 expression on Molt-4 cells. | Cellular immunology 20110101 |
Targeting epigenetic regulation of miR-34a for treatment of pancreatic cancer by inhibition of pancreatic cancer stem cells. | PloS one 20110101 |
Inhibition of DNA methylation in somatic cells. | Methods in molecular biology (Clifton, N.J.) 20110101 |
Current findings for recurring mutations in acute myeloid leukemia. | Journal of hematology & oncology 20110101 |
Promoter methylation and downregulation of SLC22A18 are associated with the development and progression of human glioma. | Journal of translational medicine 20110101 |
Hydroxyurea therapy mobilises arachidonic Acid from inner cell membrane aminophospholipids in patients with homozygous sickle cell disease. | Journal of lipids 20110101 |
MicroRNAs in rhabdomyosarcoma: pathogenetic implications and translational potentiality. | Molecular cancer 20110101 |
Systematic in-vitro evaluation of the NCI/NIH Developmental Therapeutics Program Approved Oncology Drug Set for the identification of a candidate drug repertoire for MLL-rearranged leukemia. | OncoTargets and therapy 20110101 |
Generation of reactive oxygen species during apoptosis induced by DNA-damaging agents and/or histone deacetylase inhibitors. | Oxidative medicine and cellular longevity 20110101 |
Mechanisms of mycotoxin-induced neurotoxicity through oxidative stress-associated pathways. | International journal of molecular sciences 20110101 |
Promoting illiteracy in epigenetics: an emerging therapeutic strategy. | Current chemical genomics 20110101 |
Basal LAT-diacylglycerol-RasGRP1 signals in T cells maintain TCRα gene expression. | PloS one 20110101 |
Nuclear reprogramming in mouse primordial germ cells: epigenetic contribution. | Stem cells international 20110101 |
Integrin alpha9 (ITGA9) expression and epigenetic silencing in human breast tumors. | Cell adhesion & migration 20110101 |
GSTP1 DNA methylation and expression status is indicative of 5-aza-2'-deoxycytidine efficacy in human prostate cancer cells. | PloS one 20110101 |
Market Access Agreements for pharmaceuticals in Europe: diversity of approaches and underlying concepts. | BMC health services research 20110101 |
Methylation changes associated with early maturation stages in the Atlantic salmon. | BMC genetics 20110101 |
Loss of glucocorticoid receptor expression by DNA methylation prevents glucocorticoid induced apoptosis in human small cell lung cancer cells. | PloS one 20110101 |
Age-related changes in rat bone-marrow mesenchymal stem cell plasticity. | BMC cell biology 20110101 |
miRNAs differentially expressed in prostate cancer cell lines after soy treatment. | In vivo (Athens, Greece) 20110101 |
HDAC6 regulates LPS-tolerance in astrocytes. | PloS one 20110101 |
Recent advance in antigen-specific immunotherapy for acute myeloid leukemia. | Clinical & developmental immunology 20110101 |
Systemic vasculitis with prolonged pyrexia, recurrent facial urticaria, skin nodules, pleural effusions and venous thrombosis: an unusual presentation of an uncommon disease. | German medical science : GMS e-journal 20110101 |
The role of epigenetic variation in the pathogenesis of systemic lupus erythematosus. | Arthritis research & therapy 20110101 |
Developmental mechanisms in articular cartilage degradation in osteoarthritis. | Arthritis 20110101 |
Decitabine immunosensitizes human gliomas to NY-ESO-1 specific T lymphocyte targeting through the Fas/Fas ligand pathway. | Journal of translational medicine 20110101 |
Zebularine suppresses TGF-beta-induced lens epithelial cell-myofibroblast transdifferentiation by inhibiting MeCP2. | Molecular vision 20110101 |
Genetic and epigenetic modifications of Sox2 contribute to the invasive phenotype of malignant gliomas. | PloS one 20110101 |
Manganese superoxide dismutase: guardian of the powerhouse. | International journal of molecular sciences 20110101 |
Integrated epigenetics of human breast cancer: synoptic investigation of targeted genes, microRNAs and proteins upon demethylation treatment. | PloS one 20110101 |
Epigenetics in breast cancer: what's new? | Breast cancer research : BCR 20110101 |
Methylation of miR-34a, miR-34b/c, miR-124-1 and miR-203 in Ph-negative myeloproliferative neoplasms. | Journal of translational medicine 20110101 |
A meta-analysis of CAG (cytarabine, aclarubicin, G-CSF) regimen for the treatment of 1029 patients with acute myeloid leukemia and myelodysplastic syndrome. | Journal of hematology & oncology 20110101 |
Arsenic, cadmium and neuron specific enolase (ENO2, γ-enolase) expression in breast cancer. | Cancer cell international 20110101 |
Uses of cardiomyocytes generated from induced pluripotent stem cells. | Stem cell research & therapy 20110101 |
Therapy-related myeloid malignancies in myeloma. | Mediterranean journal of hematology and infectious diseases 20110101 |
Mechanisms of neurotoxicity induced in the developing brain of mice and rats by DNA-damaging chemicals. | The Journal of toxicological sciences 20110101 |
Human cardiac stem cells isolated from atrial appendages stably express c-kit. | PloS one 20110101 |
Epigenetic mechanisms of pulmonary hypertension. | Pulmonary circulation 20110101 |
New ways to use DNA methyltransferase inhibitors for the treatment of myelodysplastic syndrome. | Hematology. American Society of Hematology. Education Program 20110101 |
Modeling neurological disorders by human induced pluripotent stem cells. | Journal of biomedicine & biotechnology 20110101 |
Cigarette smoking and p16INK4α gene promoter hypermethylation in non-small cell lung carcinoma patients: a meta-analysis. | PloS one 20110101 |
Epigenetics in prostate cancer. | Prostate cancer 20110101 |
Epigenetic silencing of IRF7 and/or IRF5 in lung cancer cells leads to increased sensitivity to oncolytic viruses. | PloS one 20110101 |
Chromatin remodeling, cell proliferation and cell death in valproic acid-treated HeLa cells. | PloS one 20110101 |
Effects of 5-azacytidine and trichostatin A on dendritic cell maturation. | Journal of biological regulators and homeostatic agents 20110101 |
Fetal hemoglobin reactivation and cell engineering in the treatment of sickle cell anemia. | Journal of blood medicine 20110101 |
Romidepsin in the treatment of cutaneous T-cell lymphoma. | Journal of blood medicine 20110101 |
Development of an oral form of azacytidine: 2'3'5'triacetyl-5-azacytidine. | Chemotherapy research and practice 20110101 |
[AntiEBV activity of 6-azacytidine and its derivatives]. | Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) 20110101 |
Methylation of secreted frizzled related protein gene in acute leukemia patients in China. | Asian Pacific journal of cancer prevention : APJCP 20110101 |
[Spontaneous and induced myogenesis in cell culture from rat fetal liver]. | Tsitologiia 20110101 |
Impact of DNA methylation on trophoblast function. | Clinical epigenetics 20110101 |
Ribavirin restores ESR1 gene expression and tamoxifen sensitivity in ESR1 negative breast cancer cell lines. | Clinical epigenetics 20110101 |
Suffocating cancer: hypoxia-associated epimutations as targets for cancer therapy. | Clinical epigenetics 20110101 |
Proliferation inhibition, cell cycle arrest and apoptosis induced in HL-60 cells by a natural diterpene ester from Daphne mucronata. | Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101 |
Integration of Principles of Systems Biology and Radiation Biology: Toward Development of in silico Models to Optimize IUdR-Mediated Radiosensitization of DNA Mismatch Repair Deficient (Damage Tolerant) Human Cancers. | Frontiers in oncology 20110101 |
Cytomegalovirus colitis following azacitidine therapy. | The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale 20110101 |
Cytogenetic effect of 5-azacytidine in patients with hematological malignancies. | Revista brasileira de hematologia e hemoterapia 20110101 |
Sequential treatment of CD34+ cells from patients with primary myelofibrosis with chromatin-modifying agents eliminate JAK2V617F-positive NOD/SCID marrow repopulating cells. | Blood 20101223 |
[Myeloproliferative/myelodysplastic syndromes]. | La Revue du praticien 20101220 |
[Current management of myelodysplastic syndromes]. | La Revue du praticien 20101220 |
The role of the DNA hypermethylating agent Budesonide in the decatenating activity of DNA topoisomerase II. | Mutation research 20101210 |
Differentiation of allogeneic mesenchymal stem cells induces immunogenicity and limits their long-term benefits for myocardial repair. | Circulation 20101207 |
Olfactomedin 4 is a novel target gene of retinoic acids and 5-aza-2'-deoxycytidine involved in human myeloid leukemia cell growth, differentiation, and apoptosis. | Blood 20101202 |
DNA methylation and carcinogenesis of PRDM5 in cervical cancer. | Journal of cancer research and clinical oncology 20101201 |
Expression, epigenetic regulation, and humoral immunogenicity of cancer-testis antigens in chronic myeloid leukemia. | Leukemia research 20101201 |
Effects of azacitidine compared with conventional care regimens in elderly (≥ 75 years) patients with higher-risk myelodysplastic syndromes. | Critical reviews in oncology/hematology 20101201 |
Reprogramming of human umbilical cord stromal mesenchymal stem cells for myogenic differentiation and muscle repair. | Stem cell reviews 20101201 |
Maintenance therapy with low-dose azacitidine after allogeneic hematopoietic stem cell transplantation for recurrent acute myelogenous leukemia or myelodysplastic syndrome: a dose and schedule finding study. | Cancer 20101201 |
A role for Gcn5 in cardiomyocyte differentiation of rat mesenchymal stem cells. | Molecular and cellular biochemistry 20101201 |
A predictive ligand-based Bayesian model for human drug-induced liver injury. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
Decitabine in myelodysplastic syndromes and chronic myelomonocytic leukemia: Argentinian/South Korean multi-institutional clinical experience. | Leukemia & lymphoma 20101201 |
Prodrugs of aza nucleosides based on proton transfer reaction. | Journal of computer-aided molecular design 20101201 |
Down-regulation of tumor suppressor A kinase anchor protein 12 in human hepatocarcinogenesis by epigenetic mechanisms. | Hepatology (Baltimore, Md.) 20101201 |
Loss of heterozygosity and DNA methylation affect germline fibroblast growth factor receptor 4 polymorphism to direct allelic selection in breast cancer. | The American journal of pathology 20101201 |
A phase II study of low dose intravenous clofarabine for elderly patients with myelodysplastic syndrome who have failed 5-azacytidine. | Leukemia & lymphoma 20101201 |
Pharmacologic induction of fetal hemoglobin production. | Hematology/oncology clinics of North America 20101201 |
Analysis of genome-wide methylation and gene expression induced by 5-aza-2'-deoxycytidine identifies BCL2L10 as a frequent methylation target in acute myeloid leukemia. | Leukemia & lymphoma 20101201 |
Tissue-specific expression of IL-15RA alternative splicing transcripts and its regulation by DNA methylation. | European cytokine network 20101201 |
Deactylase inhibition in myeloproliferative neoplasms. | Investigational new drugs 20101201 |
Histone deacetylase inhibitors in Hodgkin lymphoma. | Investigational new drugs 20101201 |
Has there been progress in the treatment of older patients with acute myeloid leukemia? | Best practice & research. Clinical haematology 20101201 |
The DAC system and associations with acute leukemias and myelodysplastic syndromes. | Investigational new drugs 20101201 |
Histone deacetylase inhibitors: potential targets responsible for their anti-cancer effect. | Investigational new drugs 20101201 |
[5-azacytidine suppresses K562 cell line proliferation by down-regulation of miR-17-19b]. | Zhongguo shi yan xue ye xue za zhi 20101201 |
Aberrant methylation of heparan sulfate glucosamine 3-O-sulfotransferase 2 genes as a biomarker in colorectal cancer. | Anticancer research 20101201 |
Gender differences in gemcitabine (Gemzar) efficacy in cancer cells: effect of indole-3-carbinol. | Anticancer research 20101201 |
Cloning and characterization of a novel gene with alternative splicing in murine mesenchymal stem cell line C3H/10T1/2 by gene trap screening. | BMB reports 20101201 |
Alphabet soup: RAEB, HMA, DOE, and AFOP. | Medicine and health, Rhode Island 20101201 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20101201 |
Epigenetic repression of SATB1 by polycomb group protein EZH2 in epithelial cells. | Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20101201 |
Economic analysis of decitabine versus best supportive care in the treatment of intermediate- and high-risk myelodysplastic syndromes from a US payer perspective. | Clinical therapeutics 20101201 |
Downregulation of miR-205 and miR-31 confers resistance to chemotherapy-induced apoptosis in prostate cancer cells. | Cell death & disease 20101201 |
Cytosine methyltransferases as tumor markers. | Current genomics 20101201 |
Measuring topology of low-intensity DNA methylation sites for high-throughput assessment of epigenetic drug-induced effects in cancer cells. | Experimental cell research 20101115 |
Long-term persistence of acquired resistance to 5-fluorouracil in the colon cancer cell line SW620. | Experimental cell research 20101115 |
Epigenetic silencing of beta-spectrin, a TGF-beta signaling/scaffolding protein in a human cancer stem cell disorder: Beckwith-Wiedemann syndrome. | The Journal of biological chemistry 20101112 |
Treatment of progression of Philadelphia-negative myeloproliferative neoplasms to myelodysplastic syndrome or acute myeloid leukemia by azacitidine: a report on 54 cases on the behalf of the Groupe Francophone des Myelodysplasies (GFM). | Blood 20101111 |
Practical use of azacitidine in higher-risk myelodysplastic syndromes: an expert panel opinion. | Leukemia research 20101101 |
Epigenetic regulation of miR-196b expression in gastric cancer. | Genes, chromosomes & cancer 20101101 |
Epigenetic inactivation of the tumor suppressor gene RIZ1 in hepatocellular carcinoma involves both DNA methylation and histone modifications. | Journal of hepatology 20101101 |
Promoter hypermethylation of progesterone receptor isoform B (PR-B) in adenomyosis and its rectification by a histone deacetylase inhibitor and a demethylation agent. | Reproductive sciences (Thousand Oaks, Calif.) 20101101 |
Decitabine increases fetal hemoglobin in Papio anubis by increasing γ-globin gene transcription. | Experimental hematology 20101101 |
Epigenetic alteration of the NF-κB-inducing kinase (NIK) gene is involved in enhanced NIK expression in basal-like breast cancer. | Cancer science 20101101 |
Importance of the tmRNA system for cell survival when transcription is blocked by DNA-protein cross-links. | Molecular microbiology 20101101 |
Aberrant demethylation of the recoverin gene is involved in the aberrant expression of recoverin in cancer cells. | Experimental dermatology 20101101 |
The effect of DNA methylation inhibitor 5-Aza-2'-deoxycytidine on human endometrial stromal cells. | Human reproduction (Oxford, England) 20101101 |
Targeting DNA methylation for epigenetic therapy. | Trends in pharmacological sciences 20101101 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
Myelodysplastic syndromes--many new drugs, little therapeutic progress. | Mayo Clinic proceedings 20101101 |
Resilience to social stress coincides with functional DNA methylation of the Crf gene in adult mice. | Nature neuroscience 20101101 |
Intratracheally administered 5-azacytidine is effective against orthotopic human lung cancer xenograft models and devoid of important systemic toxicity. | Clinical lung cancer 20101101 |
Claudin-7 down-regulation is an important feature in oral squamous cell carcinoma. | Histopathology 20101101 |
Altered DNA methylation in leukocytes with trisomy 21. | PLoS genetics 20101101 |
[Effect and mechanism of DNMT inhibitor on the reversal of multidrug resistance in human colon cancer cell line sw620/L-OHP]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20101101 |
Demethylation of a LINE-1 antisense promoter in the cMet locus impairs Met signalling through induction of illegitimate transcription. | Oncogene 20101028 |
Phase 2 study of romiplostim in patients with low- or intermediate-risk myelodysplastic syndrome receiving azacitidine therapy. | Blood 20101028 |
The novel human endogenous retrovirus-related gene, psiTPTE22-HERV, is silenced by DNA methylation in cancers. | International journal of cancer 20101015 |
Cardiomyocyte differentiation of rat bone marrow multipotent progenitor cells is associated with downregulation of Oct-4 expression. | Tissue engineering. Part A 20101001 |
Epigenetically altered wound healing in keloid fibroblasts. | The Journal of investigative dermatology 20101001 |
Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells. | Journal of molecular medicine (Berlin, Germany) 20101001 |
Phase I study of decitabine with doxorubicin and cyclophosphamide in children with neuroblastoma and other solid tumors: a Children's Oncology Group study. | Pediatric blood & cancer 20101001 |
Proteome analysis of rat bone marrow mesenchymal stem cell differentiation. | Journal of proteome research 20101001 |
DNA methylation and cellular reprogramming. | Trends in cell biology 20101001 |
Successive silencing of tandem reporter genes in potato (Solanum tuberosum) over 5 years of vegetative propagation. | Annals of botany 20101001 |
Myelodysplastic syndromes in older adults. | Clinical journal of oncology nursing 20101001 |
Methylation-mediated silencing of TMS1 in pancreatic cancer and its potential contribution to chemosensitivity. | Anticancer research 20101001 |
Fidelity variants of RNA dependent RNA polymerases uncover an indirect, mutagenic activity of amiloride compounds. | PLoS pathogens 20101001 |
[Expression, genetic and epigenetic alterations of LTF gene in nasopharyngeal carcinoma cell lines]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20101001 |
Effect of fluid shear stress on cardiomyogenic differentiation of rat bone marrow mesenchymal stem cells. | Archives of medical research 20101001 |
Synergistic induction of cell death in liver tumor cells by TRAIL and chemotherapeutic drugs via the BH3-only proteins Bim and Bid. | Cell death & disease 20101001 |
Epigenetic regulation of neonatal cardiomyocytes differentiation. | Biochemical and biophysical research communications 20100917 |
Induction of a CD8+ T-cell response to the MAGE cancer testis antigen by combined treatment with azacitidine and sodium valproate in patients with acute myeloid leukemia and myelodysplasia. | Blood 20100916 |
Effect of 5-aza-2-deoxycytidine microinjecting into hippocampus and prelimbic cortex on acquisition and retrieval of cocaine-induced place preference in C57BL/6 mice. | European journal of pharmacology 20100910 |
Determination of hypersensitivity to genotoxic agents among Escherichia coli single gene knockout mutants. | DNA repair 20100904 |
Is there an association between 5-azacitidine and ototoxicity? | Journal of clinical pharmacology 20100901 |
Demethylating agent 5-aza-2-deoxycytidine enhances susceptibility of breast cancer cells to anticancer agents. | Molecular and cellular biochemistry 20100901 |
Trex-1 deficiency in rheumatoid arthritis synovial fibroblasts. | Arthritis and rheumatism 20100901 |
Promotion of human adipose-derived stem cell proliferation mediated by exogenous nucleosides. | Cell biology international 20100901 |
A phase 1 and pharmacodynamic study of decitabine in combination with carboplatin in patients with recurrent, platinum-resistant, epithelial ovarian cancer. | Cancer 20100901 |
Azacitidine for treatment of patients with myelodysplastic syndromes (MDS): practical recommendations of the German MDS Study Group. | Annals of hematology 20100901 |
Exploiting drug repositioning for discovery of a novel HIV combination therapy. | Journal of virology 20100901 |
Effects of 17beta-estradiol and xenoestrogens on mouse embryonic stem cells. | Toxicology in vitro : an international journal published in association with BIBRA 20100901 |
Promoter hypermethylation and histone hypoacetylation contribute to pancreatic-duodenal homeobox 1 silencing in gastric cancer. | Carcinogenesis 20100901 |
Chromatin remodeling is required for gene reactivation after decitabine-mediated DNA hypomethylation. | Cancer research 20100901 |
Demethylation treatment restores hic1 expression and impairs aggressiveness of head and neck squamous cell carcinoma. | Oral oncology 20100901 |
Streptozotocin-induced diabetic rat-derived bone marrow mesenchymal stem cells have impaired abilities in proliferation, paracrine, antiapoptosis, and myogenic differentiation. | Transplantation proceedings 20100901 |
[Current treatment options for myelodysplastic syndromes]. | Deutsche medizinische Wochenschrift (1946) 20100901 |
Transplantation of 5-azacytidine treated cardiac fibroblasts improves cardiac function of infarct hearts in rats. | Chinese medical journal 20100901 |
Genomic and epigenomic instability, fragile sites, schizophrenia and autism. | Current genomics 20100901 |
Treatment of myelodysplastic syndrome transforming into acute myelogenous leukemia with azacytidine: a retrospective study from cancer centre in northern India. | Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion 20100901 |
The mechanism underlying the differentiation of human umbilical cord-derived mesenchymal stem cells into myocardial cells induced by 5-azacytidine. | Indian journal of medical sciences 20100901 |
Effects of cardiotrophin-1 on differentiation and maturation of rat bone marrow mesenchymal stem cells induced with 5-azacytidine in vitro. | International journal of cardiology 20100820 |
Up-regulation of connexin 32 gene by 5-aza-2'-deoxycytidine enhances vinblastine-induced cytotoxicity in human renal carcinoma cells via the activation of JNK signalling. | Biochemical pharmacology 20100815 |
Outcome of patients with myelodysplastic syndrome after failure of decitabine therapy. | Cancer 20100815 |
Chronic prenatal hypoxia induces epigenetic programming of PKC{epsilon} gene repression in rat hearts. | Circulation research 20100806 |
Genomic screening for genes upregulated by demethylation revealed novel targets of epigenetic silencing in breast cancer. | Breast cancer research and treatment 20100801 |
Azacytidine treatment after discontinuation of immunosuppressants in patients with myelodysplastic syndrome and relapse after allo-SCT at a single center. | Bone marrow transplantation 20100801 |
5-Azacitidine restores and amplifies the bicalutamide response on preclinical models of androgen receptor expressing or deficient prostate tumors. | The Prostate 20100801 |
Functional modulation of IGF-binding protein-3 expression in melanoma. | The Journal of investigative dermatology 20100801 |
Clinical advances in hypomethylating agents targeting epigenetic pathways. | Current cancer drug targets 20100801 |
Management and supportive care measures for adverse events in patients with myelodysplastic syndromes treated with azacitidine*. | European journal of haematology 20100801 |
Caution using hypomethylating agents in myelodysplasia or myeloid leukemia with complex cytogenetics. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100801 |
Pharmacotherapy of myelodysplastic syndromes. | Expert opinion on pharmacotherapy 20100801 |
Maintenance treatment with azacytidine for patients with high-risk myelodysplastic syndromes (MDS) or acute myeloid leukaemia following MDS in complete remission after induction chemotherapy. | British journal of haematology 20100801 |
Therapy with azanucleosides for myelodysplastic syndromes. | Nature reviews. Clinical oncology 20100801 |
S100A6 overexpression is associated with poor prognosis and is epigenetically up-regulated in gastric cancer. | The American journal of pathology 20100801 |
Global DNA methylation in fetal human germ cells and germ cell tumours: association with differentiation and cisplatin resistance. | The Journal of pathology 20100801 |
CpG hypermethylation of human four-and-a-half LIM domains 1 contributes to migration and invasion activity of human bladder cancer. | International journal of molecular medicine 20100801 |
Validation of a novel statistical model for assessing the synergy of combined-agent cancer chemoprevention. | Cancer prevention research (Philadelphia, Pa.) 20100801 |
Identification of novel methylation markers in hepatocellular carcinoma using a methylation array. | Journal of Korean medical science 20100801 |
Combinations of DNA methyltransferase and histone deacetylase inhibitors induce DNA damage in small cell lung cancer cells: correlation of resistance with IFN-stimulated gene expression. | Molecular cancer therapeutics 20100801 |
Fetal globin gene inducers: novel agents and new potential. | Annals of the New York Academy of Sciences 20100801 |
CTCF prevents the epigenetic drift of EBV latency promoter Qp. | PLoS pathogens 20100801 |
A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape. | PLoS pathogens 20100801 |
[Study on promoter methylation status of E-cadherin gene in nasopharyngeal carcinoma cell lines]. | Zhonghua bing li xue za zhi = Chinese journal of pathology 20100801 |
DNA instability at chromosomal fragile sites in cancer. | Current genomics 20100801 |
Current and future management options for myelodysplastic syndromes. | Drugs 20100730 |
Epigenetic regulation of vitamin D 24-hydroxylase/CYP24A1 in human prostate cancer. | Cancer research 20100715 |
MAD2 downregulation in hypoxia is independent of promoter hypermethylation. | Cell cycle (Georgetown, Tex.) 20100715 |
The functional significance of microRNA-145 in prostate cancer. | British journal of cancer 20100713 |
In vivo administration of hypomethylating agents mitigate graft-versus-host disease without sacrificing graft-versus-leukemia. | Blood 20100708 |
Rapid determination of AKAP12 promoter methylation levels in peripheral blood using methylation-sensitive high resolution melting (MS-HRM) analysis: application in colorectal cancer. | Clinica chimica acta; international journal of clinical chemistry 20100704 |
Down-regulation of mitochondrial ATPase by hypermethylation mechanism in chronic myeloid leukemia is associated with multidrug resistance. | Annals of oncology : official journal of the European Society for Medical Oncology 20100701 |
Changes in chromatin structure and methylation of the human interleukin-1beta gene during monopoiesis. | Immunology 20100701 |
VDR microRNA expression and epigenetic silencing of vitamin D signaling in melanoma cells. | The Journal of steroid biochemistry and molecular biology 20100701 |
Epigenetic regulation affects N-myc downstream-regulated gene 1 expression indirectly in pancreatic cancer cells. | Pancreas 20100701 |
Establishment and characterization of multi-drug resistant, prostate carcinoma-initiating stem-like cells from human prostate cancer cell lines 22RV1. | Molecular and cellular biochemistry 20100701 |
Sequential loss of cell cycle checkpoint control contributes to malignant transformation of murine embryonic fibroblasts induced by 20-methylcholanthrene. | Journal of cellular physiology 20100701 |
Predictive value of pretreatment risk group and baseline LDH levels in MDS patients receiving azacitidine treatment. | Annals of hematology 20100701 |
Vectorial transport of nucleoside analogs from the apical to the basolateral membrane in double-transfected cells expressing the human concentrative nucleoside transporter hCNT3 and the export pump ABCC4. | Drug metabolism and disposition: the biological fate of chemicals 20100701 |
Modulation of E-cadherin expression by K-Ras; involvement of DNA methyltransferase-3b. | Carcinogenesis 20100701 |
The DNA demethylating agent 5-aza-2'-deoxycytidine induces expression of NY-ESO-1 and other cancer/testis antigens in myeloid leukemia cells. | Leukemia research 20100701 |
DNA methylation-related vitamin D receptor insensitivity in breast cancer. | Cancer biology & therapy 20100701 |
Epigenetic regulation of photoperiodic flowering. | Plant signaling & behavior 20100701 |
Phase I trial of low dose decitabine targeting DNA hypermethylation in patients with chronic lymphocytic leukaemia and non-Hodgkin lymphoma: dose-limiting myelosuppression without evidence of DNA hypomethylation. | British journal of haematology 20100701 |
WHO-defined 'myelodysplastic syndrome with isolated del(5q)' in 88 consecutive patients: survival data, leukemic transformation rates and prevalence of JAK2, MPL and IDH mutations. | Leukemia 20100701 |
Early growth response-1 induces and enhances vascular endothelial growth factor-A expression in lung cancer cells. | The American journal of pathology 20100701 |
DNA methylation of interferon regulatory factors in gastric cancer and noncancerous gastric mucosae. | Cancer science 20100701 |
Long-term stability of demethylation after transient exposure to 5-aza-2'-deoxycytidine correlates with sustained RNA polymerase II occupancy. | Molecular cancer research : MCR 20100701 |
[Differentiation of 5-azacytidine-induced bone marrow stromal stem cells transduced with hepatocyte growth factor gene]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20100701 |
Screening for methylation-silenced genes in acute myeloid leukemia HL-60 cell line by a quantitative proteomic approach. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20100701 |
[Experimental study on effect of monocyte chemoattractant protein 1 on migration of induced and differentiated mouse bone marrow mesenchymal stem cells in vitro]. | Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20100701 |
Promoter hypomethylation contributes to the expression of MUC3A in cancer cells. | Biochemical and biophysical research communications 20100625 |
Eleventh biannual report of the Cochrane Haematological Malignancies Group: Focus on Hodgkin lymphoma. | Journal of the National Cancer Institute 20100616 |
Downregulation of WIF-1 by hypermethylation in astrocytomas. | Acta biochimica et biophysica Sinica 20100615 |
Promoter hypermethylation in MLL-r infant acute lymphoblastic leukemia: biology and therapeutic targeting. | Blood 20100610 |
Methylation of PARP-1 promoter involved in the regulation of benzene-induced decrease of PARP-1 mRNA expression. | Toxicology letters 20100602 |
5-Aza-2'-deoxycytidine is a potent inhibitor of DNA methyltransferase 3B and induces apoptosis in human endometrial cancer cell lines with the up-regulation of hMLH1. | Medical oncology (Northwood, London, England) 20100601 |
Identification of a novel human cancer/testis gene MAEL that is regulated by DNA methylation. | Molecular biology reports 20100601 |
Induction of apoptosis of non-small cell lung cancer by a methylated oligonucleotide targeting survivin gene. | Cancer gene therapy 20100601 |
Epigenetic therapy in myelodysplastic syndromes. | European journal of haematology 20100601 |
Role of Ucp1 enhancer methylation and chromatin remodelling in the control of Ucp1 expression in murine adipose tissue. | Diabetologia 20100601 |
Quantitative assessment of AKAP12 promoter methylation in colorectal cancer using methylation-sensitive high resolution melting: Correlation with Duke's stage. | Cancer biology & therapy 20100601 |
Pharmacoepigenetics in heart failure. | Current heart failure reports 20100601 |
DNA methylation contributes to loss in productivity of monoclonal antibody-producing CHO cell lines. | Journal of biotechnology 20100601 |
Epigenetic mechanisms of promigratory chemokine CXCL14 regulation in human prostate cancer cells. | Cancer research 20100601 |
Decitabine maintains hematopoietic precursor self-renewal by preventing repression of stem cell genes by a differentiation-inducing stimulus. | Molecular cancer therapeutics 20100601 |
Feasibility of therapy with hypomethylating agents in patients with renal insufficiency. | Clinical lymphoma, myeloma & leukemia 20100601 |
An update on the treatment of myelodysplastic syndromes. | Clinical journal of oncology nursing 20100601 |
Induced differentiation of adipose-derived stromal cells into myoblasts. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20100601 |
Function and regulatory mechanisms of the candidate tumor suppressor receptor protein tyrosine phosphatase gamma (PTPRG) in breast cancer cells. | Anticancer research 20100601 |
DNA and histone deacetylases as targets for neuroblastoma treatment. | Interdisciplinary toxicology 20100601 |
Chemical epigenetics alters the secondary metabolite composition of guttate excreted by an atlantic-forest-soil-derived Penicillium citreonigrum. | Journal of natural products 20100528 |
Effect of 5-aza-2'-deoxycytidine on immune-associated proteins in exosomes from hepatoma. | World journal of gastroenterology 20100521 |
[The relationship between the TSLC1 silencing and DNA methylation in human lung cancer cells]. | Zhongguo fei ai za zhi = Chinese journal of lung cancer 20100520 |
Assessing the DNA methylation status of single cells with the comet assay. | Analytical biochemistry 20100515 |
Progression to metastatic stage in a cellular model of prostate cancer is associated with methylation of the androgen receptor gene and transcriptional suppression of the insulin-like growth factor-I receptor gene. | Experimental cell research 20100515 |
5-Azacytidine for the treatment of patients with acute myeloid leukemia or myelodysplastic syndrome who relapse after allo-SCT: a retrospective analysis. | Bone marrow transplantation 20100501 |
FOXE1 is a target for aberrant methylation in cutaneous squamous cell carcinoma. | The British journal of dermatology 20100501 |
Role of histone modifications and DNA methylation in the regulation of O6-methylguanine-DNA methyltransferase gene expression in human stomach cancer cells. | Cancer investigation 20100501 |
Generation of antigen-presenting cells from tumor-infiltrated CD11b myeloid cells with DNA demethylating agent 5-aza-2'-deoxycytidine. | Cancer immunology, immunotherapy : CII 20100501 |
Neutrophilic eccrine hidradenitis associated with decitabine. | Leukemia research 20100501 |
Involvement of epigenetically silenced microRNA-181c in gastric carcinogenesis. | Carcinogenesis 20100501 |
Exposure to cardiomyogenic stimuli fails to transdifferentiate human umbilical cord blood-derived mesenchymal stem cells. | Basic research in cardiology 20100501 |
Regulation of human endogenous retrovirus-K expression in melanomas by CpG methylation. | Genes, chromosomes & cancer 20100501 |
Aberrant methylation impairs low density lipoprotein receptor-related protein 1B tumor suppressor function in gastric cancer. | Genes, chromosomes & cancer 20100501 |
Long-term AZT exposure alters the metabolic capacity of cultured human lymphoblastoid cells. | Toxicological sciences : an official journal of the Society of Toxicology 20100501 |
Decreased fibronectin production significantly contributes to dysregulated repair of asthmatic epithelium. | American journal of respiratory and critical care medicine 20100501 |
Epigenetically regulated clonal heritability of CTA expression profiles in human melanoma. | Journal of cellular physiology 20100501 |
TWIST1 hypermethylation is observed frequently in colorectal tumors and its overexpression is associated with unfavorable outcomes in patients with colorectal cancer. | Genes, chromosomes & cancer 20100501 |
Phase I combination trial of lenalidomide and azacitidine in patients with higher-risk myelodysplastic syndromes. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100501 |
5-Aza-2'-deoxycytidine treatment induces skeletal myogenic differentiation of mouse dental pulp stem cells. | Archives of oral biology 20100501 |
Altered DNA methylation is associated with docetaxel resistance in human breast cancer cells. | International journal of oncology 20100501 |
[Epigenetic therapy in myelodysplastic syndromes (MDS). Treatment with DNA methyltransferase inhibitors]. | Pharmazie in unserer Zeit 20100501 |
Advances in the management of acute myeloid leukemia in older adult patients. | Oncology nursing forum 20100501 |
S110, a 5-Aza-2'-deoxycytidine-containing dinucleotide, is an effective DNA methylation inhibitor in vivo and can reduce tumor growth. | Molecular cancer therapeutics 20100501 |
Delivery of 5-azacytidine to human cancer cells by elaidic acid esterification increases therapeutic drug efficacy. | Molecular cancer therapeutics 20100501 |
Azacitidine for the treatment of myelodysplastic syndrome, chronic myelomonocytic leukaemia and acute myeloid leukaemia. | Health technology assessment (Winchester, England) 20100501 |
Enhancement of cardiomyocyte differentiation from human embryonic stem cells. | Science China. Life sciences 20100501 |
Phase 2 clinical trial of 5-azacitidine, valproic acid, and all-trans retinoic acid in patients with high-risk acute myeloid leukemia or myelodysplastic syndrome. | Oncotarget 20100501 |
Epigenetic repression of PDZ-LIM domain-containing protein 2: implications for the biology and treatment of breast cancer. | The Journal of biological chemistry 20100416 |
Differential regulation of the dioxin-induced Cyp1a1 and Cyp1b1 genes in mouse hepatoma and fibroblast cell lines. | Toxicology letters 20100415 |
Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells. | Breast cancer research and treatment 20100401 |
CpG island methylation affects accessibility of the proximal BRCA1 promoter to transcription factors. | Breast cancer research and treatment 20100401 |
Reduction of 5-azacitidine induced skin reactions in MDS patients with evening primrose oil. | Annals of hematology 20100401 |
Efficacy of a 3-day, low-dose treatment with 5-azacytidine followed by donor lymphocyte infusions in older patients with acute myeloid leukemia or chronic myelomonocytic leukemia relapsed after allografting. | Bone marrow transplantation 20100401 |
Effects of decitabine on the expression of selected endogenous control genes in human breast cancer cells. | Molecular and cellular probes 20100401 |
Effects of 5-azacytidine on lymphocyte-metaphases of Creole cows carrying the rob(1;29). | Research in veterinary science 20100401 |
Increased CXCR4 expression in AsPC1 pancreatic carcinoma cells with RNA interference-mediated knockdown of DNMT1 and DNMT3B. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100401 |
Direct and transgenerational impact on Daphnia magna of chemicals with a known effect on DNA methylation. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20100401 |
Differentiation of human adipose-derived stem cells into beating cardiomyocytes. | Journal of cellular and molecular medicine 20100401 |
CpG methylation attenuates Sp1 and Sp3 binding to the human extracellular superoxide dismutase promoter and regulates its cell-specific expression. | Free radical biology & medicine 20100401 |
Inheritance of acquired traits in plants: reinstatement of Lamarck. | Plant signaling & behavior 20100401 |
In vitro assessment of cytochrome P450 inhibition and induction potential of azacitidine. | Cancer chemotherapy and pharmacology 20100401 |
Epigenetic mediated transcriptional activation of PARP-1 participates in silica-associated malignant transformation of human bronchial epithelial cells. | Toxicology letters 20100401 |
Molecular genetic and epigenetic analysis of NCX2/SLC8A2 at 19q13.3 in human gliomas. | Neuropathology and applied neurobiology 20100401 |
Prolonged survival with improved tolerability in higher-risk myelodysplastic syndromes: azacitidine compared with low dose ara-C. | British journal of haematology 20100401 |
The effect of epigenetic therapy on congenital neurogenic bladders--a pilot study. | Urology 20100401 |
Expression and regulation mechanisms of Sonic Hedgehog in breast cancer. | Cancer science 20100401 |
Porcupine expression is associated with the expression of S100P and other cancer-related molecules in non-small cell lung carcinoma. | International journal of oncology 20100401 |
Identification of hypermethylated genes associated with cisplatin resistance in human cancers. | Cancer research 20100401 |
Predonor lymphocyte infusion treatment with 5-azacytidine as salvage treatment in relapsed acute myeloid leukaemia secondary to myelodysplastic syndrome. | Anti-cancer drugs 20100401 |
Impact of genomic methylation on radiation sensitivity of colorectal carcinoma. | International journal of radiation oncology, biology, physics 20100401 |
Upregulation of DNA methyltransferase-mediated gene silencing, anchorage-independent growth, and migration of colon cancer cells by interleukin-6. | Molecular cancer research : MCR 20100401 |
Preface. The biology and treatment of myelodysplastic syndrome. | Hematology/oncology clinics of North America 20100401 |
Epigenetic changes in the myelodysplastic syndrome. | Hematology/oncology clinics of North America 20100401 |
Practical recommendations for hypomethylating agent therapy of patients with myelodysplastic syndromes. | Hematology/oncology clinics of North America 20100401 |
[No correlation between the sensitivity to 5-aza-dC and the global DNA methylation level in hepatocellular carcinoma cells]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20100401 |
Hypermethylation downregulates Runx3 gene expression and its restoration suppresses gastric epithelial cell growth by inducing p27 and caspase3 in human gastric cancer. | Journal of gastroenterology and hepatology 20100401 |
DNA methylation-mediated down-regulation of DNA methyltransferase-1 (DNMT1) is coincident with, but not essential for, global hypomethylation in human placenta. | The Journal of biological chemistry 20100326 |
Differential epigenetic regulation of BDNF and NT-3 genes by trichostatin A and 5-aza-2'-deoxycytidine in Neuro-2a cells. | Biochemical and biophysical research communications 20100326 |
IGFBP-3 hypermethylation-derived deficiency mediates cisplatin resistance in non-small-cell lung cancer. | Oncogene 20100318 |
Elevated MAL expression is accompanied by promoter hypomethylation and platinum resistance in epithelial ovarian cancer. | International journal of cancer 20100315 |
Azacitidine for the treatment of lower risk myelodysplastic syndromes : a retrospective study of 74 patients enrolled in an Italian named patient program. | Cancer 20100315 |
DNA demethylation in retinal neurocytes contributes to the upregulation of DNA repair protein, Ku80. | Neuroreport 20100310 |
RA induces the neural-like cells generated from epigenetic modified NIH/3T3 cells. | Molecular biology reports 20100301 |
IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype. | Carcinogenesis 20100301 |
5-Aza-2'-deoxycytidine sensitizes busulfan-resistant myeloid leukemia cells by regulating expression of genes involved in cell cycle checkpoint and apoptosis. | Leukemia research 20100301 |
Killer cell immunoglobulin-like receptor expression induction on neonatal CD8(+) T cells in vitro and following congenital infection with Trypanosoma cruzi. | Immunology 20100301 |
DNA methylation regulates adenosine A(2A) receptor cell surface expression levels. | Journal of neurochemistry 20100301 |
Maintenance therapy in acute myeloid leukemia revisited: will new agents rekindle an old interest? | Current opinion in hematology 20100301 |
Prolonged responses in patients with MDS and CMML treated with azacitidine and etanercept. | British journal of haematology 20100301 |
Promoter hypermethylation of FBXO32, a novel TGF-beta/SMAD4 target gene and tumor suppressor, is associated with poor prognosis in human ovarian cancer. | Laboratory investigation; a journal of technical methods and pathology 20100301 |
DNA methylation-dependent repression of PDZ-LIM domain-containing protein 2 in colon cancer and its role as a potential therapeutic target. | Cancer research 20100301 |
Long-term survival and characterisation of human umbilical cord-derived mesenchymal stem cells on dermal equivalents. | Differentiation; research in biological diversity 20100301 |
Novel approaches for myelodysplastic syndromes: beyond hypomethylating agents. | Current opinion in hematology 20100301 |
The effects of DNA methyltransferase inhibitors and histone deacetylase inhibitors on digit regeneration in mice. | Regenerative medicine 20100301 |
Valproic acid in the complex therapy of malignant tumors. | Current drug targets 20100301 |
Antineoplastic effects of decitabine, an inhibitor of DNA promoter methylation, in adrenocortical carcinoma cells. | Archives of surgery (Chicago, Ill. : 1960) 20100301 |
[Effects of 5-Aza-2'-deoxycitydine and trichostatin A on expression and apoptosis of ALDH1a2 gene in human bladder cancer cell lines]. | Zhonghua wai ke za zhi [Chinese journal of surgery] 20100301 |
JAK2 V617F mutation in myelodysplastic syndrome, myelodysplastic syndrome/myeloproliferative neoplasm, unclassifiable, refractory anemia with ring sideroblasts with thrombocytosis, and acute myeloid leukemia. | The Korean journal of hematology 20100301 |
Epigenetic silencing of TNFSF7 (CD70) by DNA methylation during progression to breast cancer. | Molecules and cells 20100227 |
hGH-V gene expression and promoter activity under glucose and 5-azacytidine (5azaC) effects. | Gene 20100215 |
X-linked ectodermal dysplasia receptor is downregulated in breast cancer via promoter methylation. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100215 |
Use of Drosophila deoxynucleoside kinase to study mechanism of toxicity and mutagenicity of deoxycytidine analogs in Escherichia coli. | DNA repair 20100204 |
5-Azacitidine for myelodysplasia before allogeneic hematopoietic cell transplantation. | Bone marrow transplantation 20100201 |
Fabrication of novel hepatoma-targeting microdisks by hydrogen bond-assisted self-assembly of an azacitidine-conjugating amphiphilic random copolymer. | Acta biomaterialia 20100201 |
Outcome prediction and risk assessment by quantitative pyrosequencing methylation analysis of the SFN gene in advanced stage, high-risk, neuroblastic tumor patients. | International journal of cancer 20100201 |
Aberrant DNA methylation of integrin alpha4: a potential novel role for metastasis of cholangiocarcinoma. | Journal of cancer research and clinical oncology 20100201 |
Preclinical antileukemia activity of JNJ-26481585, a potent second-generation histone deacetylase inhibitor. | Leukemia research 20100201 |
5-azacitidine prolongs overall survival in patients with myelodysplastic syndrome--a systematic review and meta-analysis. | Haematologica 20100201 |
Epigenetics: methylation-associated repression of heparan sulfate 3-O-sulfotransferase gene expression contributes to the invasive phenotype of H-EMC-SS chondrosarcoma cells. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20100201 |
Inhibition of methylation decreases osteoblast differentiation via a non-DNA-dependent methylation mechanism. | Bone 20100201 |
Decitabine versus 5-azacitidine for the treatment of myelodysplastic syndrome: adjusted indirect meta-analysis. | Haematologica 20100201 |
Cardiomyogenic differentiation of human bone marrow mesenchymal cells: Role of cardiac extract from neonatal rat cardiomyocytes. | Differentiation; research in biological diversity 20100201 |
Resistance to 5-aza-2'-deoxycytidine in genic regions compared to non-genic repetitive sequences. | The Journal of reproduction and development 20100201 |
Multicenter, phase II study of decitabine for the first-line treatment of older patients with acute myeloid leukemia. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100201 |
Azacitidine prolongs overall survival compared with conventional care regimens in elderly patients with low bone marrow blast count acute myeloid leukemia. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100201 |
Growth-inhibiting effects of arsenic trioxide plus epigenetic therapeutic agents on leukemia cell lines. | Leukemia & lymphoma 20100201 |
DNA methylation and its involvement in carboxylesterase 1A1 (CES1A1) gene expression. | Xenobiotica; the fate of foreign compounds in biological systems 20100201 |
Vitamin D stimulates apoptosis in gastric cancer cells in synergy with trichostatin A /sodium butyrate-induced and 5-aza-2'-deoxycytidine-induced PTEN upregulation. | The FEBS journal 20100201 |
Tissue factor pathway inhibitor 2 (TFPI2) is frequently silenced by aberrant promoter hypermethylation in gastric cancer. | Cancer genetics and cytogenetics 20100201 |
Stem cell therapy: pieces of the puzzle. | Journal of cardiovascular translational research 20100201 |
The role of C1GALT1C1 in lipopolysaccharide-induced IgA1 aberrant O-glycosylation in IgA nephropathy. | Clinical and investigative medicine. Medecine clinique et experimentale 20100201 |
Age-associated epigenetic modifications in human DNA increase its immunogenicity. | Aging 20100201 |
Effective control of sickle cell disease with hydroxyurea therapy. | Indian journal of pharmacology 20100201 |
Will DNA methylation inhibitors work in solid tumors? A review of the clinical experience with azacitidine and decitabine in solid tumors. | Epigenomics 20100201 |
Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition. | Oncogene 20100128 |
Immune dysregulation in myelodysplastic syndrome. | Hematology reports 20100126 |
DNA methyltransferase inhibition induces mouse embryonic stem cell differentiation into endothelial cells. | Experimental cell research 20100115 |
Efficient readout of posttranslational codes on the 50-residue tail of histone H3 by high-resolution MS/MS. | Analytical biochemistry 20100115 |
DNA methyltransferase inhibitors increase baculovirus-mediated gene expression in mammalian cells when applied before infection. | Analytical biochemistry 20100115 |
Epigenetic mechanisms modulate thyroid transcription factor 1-mediated transcription of the surfactant protein B gene. | The Journal of biological chemistry 20100115 |
Controlling destiny through chemistry: small-molecule regulators of cell fate. | ACS chemical biology 20100115 |
SLIT2 attenuation during lung cancer progression deregulates beta-catenin and E-cadherin and associates with poor prognosis. | Cancer research 20100115 |
Immunomodulatory effect of 5-azacytidine (5-azaC): potential role in the transplantation setting. | Blood 20100107 |
Comparison of various criteria in predicting treatment response and prognosis of patients with myelodysplastic syndrome treated with azacitidine. | Annals of hematology 20100101 |
Frequent methylation of RASSF1A in synovial sarcoma and the anti-tumor effects of 5-aza-2'-deoxycytidine against synovial sarcoma cell lines. | Journal of cancer research and clinical oncology 20100101 |
Incorporating novel agents in the treatment of myelodysplastic syndromes. | Leukemia research 20100101 |
Regulation of Toll-like receptor 4-associated MD-2 in intestinal epithelial cells: a comprehensive analysis. | Innate immunity 20100101 |
Stability of transgenes in long-term micropropagation of plants of transgenic birch (Betula platyphylla). | Biotechnology letters 20100101 |
Frequent epigenetic inactivation of the receptor tyrosine kinase EphA5 by promoter methylation in human breast cancer. | Human pathology 20100101 |
Impaired active demethylation of the paternal genome in pronuclear-stage rat zygotes produced by in vitro fertilization or intracytoplasmic sperm injection. | Molecular reproduction and development 20100101 |
Tamoxifen epigenetically modulates CXCL12 expression in MCF-7 breast cancer cells. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100101 |
Successful treatment of molecular relapse in NPM1-positive AML using 5-azacytidine. | Leukemia 20100101 |
Expression and function of CD9 in melanoma cells. | Molecular carcinogenesis 20100101 |
Gene silencing of MIR22 in acute lymphoblastic leukaemia involves histone modifications independent of promoter DNA methylation. | British journal of haematology 20100101 |
Oncogenic BRAFV600E induces expression of neuronal differentiation marker MAP2 in melanoma cells by promoter demethylation and down-regulation of transcription repressor HES1. | The Journal of biological chemistry 20100101 |
Identification of a functional network of human epigenetic silencing factors. | The Journal of biological chemistry 20100101 |
5'-AZA induces Ngn3 expression and endocrine differentiation in the PANC-1 human ductal cell line. | Biochemical and biophysical research communications 20100101 |
DNA methylation-dependent suppression of HIF1A in an immature hematopoietic cell line HMC-1. | Biochemical and biophysical research communications 20100101 |
Decitabine in the treatment of myelodysplastic syndromes. | Expert review of anticancer therapy 20100101 |
Report of a phase 1/2 study of a combination of azacitidine and cytarabine in acute myelogenous leukemia and high-risk myelodysplastic syndromes. | Leukemia & lymphoma 20100101 |
[Effect of 5-Aza-CdR on expression and methylation of E-cadherin gene in human colon carcinoma cells]. | Chinese journal of cancer 20100101 |
Multifactorial regulation of E-cadherin expression: an integrative study. | Molecular cancer therapeutics 20100101 |
Global methylation pattern of genes in androgen-sensitive and androgen-independent prostate cancer cells. | Molecular cancer therapeutics 20100101 |
Myelodysplastic syndromes. | Annual review of medicine 20100101 |
Nrf2 expression is regulated by epigenetic mechanisms in prostate cancer of TRAMP mice. | PloS one 20100101 |
Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma. | Neoplasia (New York, N.Y.) 20100101 |
Decitabine. | Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20100101 |
5-Azacytidine/Azacitidine. | Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20100101 |
Regulation of UGT1A1 and HNF1 transcription factor gene expression by DNA methylation in colon cancer cells. | BMC molecular biology 20100101 |
Serial bone marrow transplantation reveals in vivo expression of the pCLPG retroviral vector. | Virology journal 20100101 |
Cooperation of multiple chromatin modifications can generate unanticipated stability of epigenetic States in Arabidopsis. | The Plant cell 20100101 |
The site specific demethylation in the 5'-regulatory area of NMDA receptor 2B subunit gene associated with CIE-induced up-regulation of transcription. | PloS one 20100101 |
A comparison of azacitidine and decitabine activities in acute myeloid leukemia cell lines. | PloS one 20100101 |
Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents. | Journal of hematology & oncology 20100101 |
Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation. | BMC cancer 20100101 |
Genome-wide methylation and expression profiling identifies promoter characteristics affecting demethylation-induced gene up-regulation in melanoma. | BMC medical genomics 20100101 |
Osteopontin regulates human glioma cell invasiveness and tumor growth in mice. | Neuro-oncology 20100101 |
A role for age-related changes in TGFbeta signaling in aberrant chondrocyte differentiation and osteoarthritis. | Arthritis research & therapy 20100101 |
Lsh mediated RNA polymerase II stalling at HoxC6 and HoxC8 involves DNA methylation. | PloS one 20100101 |
Analysis of an alternative human CD133 promoter reveals the implication of Ras/ERK pathway in tumor stem-like hallmarks. | Molecular cancer 20100101 |
[Effectiveness and safety of 5-azacitidine in three patients with myelodysplastic syndromes]. | Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20100101 |
Genomic variants associated with primary biliary cirrhosis. | Genome medicine 20100101 |
Regulation of gene expression in protozoa parasites. | Journal of biomedicine & biotechnology 20100101 |
Transgenerational adaptation of Arabidopsis to stress requires DNA methylation and the function of Dicer-like proteins. | PloS one 20100101 |
Mechanical strain modulates age-related changes in the proliferation and differentiation of mouse adipose-derived stromal cells. | BMC cell biology 20100101 |
Temozolomide-induced myelodysplasia. | Advances in hematology 20100101 |
BORIS (CTCFL) is not expressed in most human breast cell lines and high grade breast carcinomas. | PloS one 20100101 |
A quantitative proteomic analysis of long-term memory. | Molecular brain 20100101 |
[Elderly patients with myelodysplastic syndrome with del 5q receiving lenalidomide: two case reports with poor prognosis]. | Annales de biologie clinique 20100101 |
Hypomethylating agent induction therapy followed by hematopoietic cell transplantation is feasible in patients with myelodysplastic syndromes. | Clinical advances in hematology & oncology : H&O 20100101 |
Circadian rhythm and its role in malignancy. | Journal of circadian rhythms 20100101 |
Red blood cell transfusion independence following the initiation of iron chelation therapy in myelodysplastic syndrome. | Advances in hematology 20100101 |
Effective and steady differentiation of a clonal derivative of P19CL6 embryonal carcinoma cell line into beating cardiomyocytes. | Journal of biomedicine & biotechnology 20100101 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20100101 |
Combination stem cell therapy for heart failure. | International archives of medicine 20100101 |
Functional neural differentiation of human adipose tissue-derived stem cells using bFGF and forskolin. | BMC cell biology 20100101 |
Cell-based therapy for urinary incontinence. | Korean journal of urology 20100101 |
Oral Ezatiostat HCl (TLK199) and Myelodysplastic syndrome: a case report of sustained hematologic response following an abbreviated exposure. | Journal of hematology & oncology 20100101 |
Novel agents and regimens for acute myeloid leukemia: 2009 ASH annual meeting highlights. | Journal of hematology & oncology 20100101 |
Epigenetic mechanisms regulate MHC and antigen processing molecules in human embryonic and induced pluripotent stem cells. | PloS one 20100101 |
NGX6 gene mediated by promoter methylation as a potential molecular marker in colorectal cancer. | BMC cancer 20100101 |
High-risk myelodysplastic syndromes: chemotherapy, transplantation, and beyond. | Current hematologic malignancy reports 20100101 |
[Effect of 5-azadeoxycytidine and retinoic acid on expression of genomic imprinting in parthenogenetic mouse embryos]. | Ontogenez 20100101 |
Melanoma: Stem cells, sun exposure and hallmarks for carcinogenesis, molecular concepts and future clinical implications. | Journal of carcinogenesis 20100101 |
The apelin-APJ pathway exists in cardiomyogenic cells derived from mesenchymal stem cells in vitro and in vivo. | Cell transplantation 20100101 |
HOXB13, a target of DNMT3B, is methylated at an upstream CpG island, and functions as a tumor suppressor in primary colorectal tumors. | PloS one 20100101 |
BISMA--fast and accurate bisulfite sequencing data analysis of individual clones from unique and repetitive sequences. | BMC bioinformatics 20100101 |
Genome-wide changes accompanying the knockdown of Ep-CAM in retinoblastoma. | Molecular vision 20100101 |
Seladin-1 expression is regulated by promoter methylation in adrenal cancer. | BMC cancer 20100101 |
Beta-thalassemia. | Orphanet journal of rare diseases 20100101 |
The aberrant asynchronous replication - characterizing lymphocytes of cancer patients - is erased following stem cell transplantation. | BMC cancer 20100101 |
Nucleoside drugs induce cellular differentiation by caspase-dependent degradation of stem cell factors. | PloS one 20100101 |
Vascular endothelial growth factor-related pathways in hemato-lymphoid malignancies. | Journal of oncology 20100101 |
Active chromatin marks are retained on X chromosomes lacking gene or repeat silencing despite XIST/Xist expression in somatic cell hybrids. | PloS one 20100101 |
Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma. | BMC cancer 20100101 |
Impaired cell surface expression of HLA-B antigens on mesenchymal stem cells and muscle cell progenitors. | PloS one 20100101 |
Epigenetics of human cutaneous melanoma: setting the stage for new therapeutic strategies. | Journal of translational medicine 20100101 |
Epigenetic alterations differ in phenotypically distinct human neuroblastoma cell lines. | BMC cancer 20100101 |
An in vitro system for studying murid herpesvirus-4 latency and reactivation. | PloS one 20100101 |
Active loss of DNA methylation in two-cell stage goat embryos. | The International journal of developmental biology 20100101 |
Multiple mesodermal lineage differentiation of Apodemus sylvaticus embryonic stem cells in vitro. | BMC cell biology 20100101 |
Expression of RAN, ZHX-2, and CHC1L genes in multiple myeloma patients and in myeloma cell lines treated with HDAC and Dnmts inhibitors. | Neoplasma 20100101 |
Clinical trials with anti-angiogenic agents in hematological malignancies. | Journal of angiogenesis research 20100101 |
The Wnt inhibitory factor 1 restoration in prostate cancer cells was associated with reduced tumor growth, decreased capacity of cell migration and invasion and a reversal of epithelial to mesenchymal transition. | Molecular cancer 20100101 |
Hypomethylation of IL10 and IL13 promoters in CD4+ T cells of patients with systemic lupus erythematosus. | Journal of biomedicine & biotechnology 20100101 |
Azacytidine induces cell cycle arrest and suppression of neuroendocrine markers in carcinoids. | International journal of clinical and experimental medicine 20100101 |
Altered intra-nuclear organisation of heterochromatin and genes in ICF syndrome. | PloS one 20100101 |
An update on the safety and efficacy of decitabine in the treatment of myelodysplastic syndromes. | OncoTargets and therapy 20100101 |
Demethylation by 5-aza-2'-deoxycytidine in colorectal cancer cells targets genomic DNA whilst promoter CpG island methylation persists. | BMC cancer 20100101 |
Cytokine-induced monocyte characteristics in SLE. | Journal of biomedicine & biotechnology 20100101 |
Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines. | PloS one 20100101 |
Exon 2 methylation inhibits hepaCAM expression in transitional cell carcinoma of the bladder. | Urologia internationalis 20100101 |
Challenges in treating older patients with acute myeloid leukemia. | Journal of oncology 20100101 |
BORIS/CTCFL expression is insufficient for cancer-germline antigen gene expression and DNA hypomethylation in ovarian cell lines. | Cancer immunity 20100101 |
Soy phytoestrogens modify DNA methylation of GSTP1, RASSF1A, EPH2 and BRCA1 promoter in prostate cancer cells. | In vivo (Athens, Greece) 20100101 |
Overexpression of hTERT increases stem-like properties and decreases spontaneous differentiation in human mesenchymal stem cell lines. | Journal of biomedical science 20100101 |
Personalized therapies in the cancer 'omics' era. | Molecular cancer 20100101 |
Oxidative stress and DNA methylation in prostate cancer. | Obstetrics and gynecology international 20100101 |
Remodeling genomes with artificial transcription factors (ATFs). | Methods in molecular biology (Clifton, N.J.) 20100101 |
Trichostatin A and 5-azacytidine both cause an increase in global histone H4 acetylation and a decrease in global DNA and H3K9 methylation during mitosis in maize. | BMC plant biology 20100101 |
Transpositional reactivation of the Dart transposon family in rice lines derived from introgressive hybridization with Zizania latifolia. | BMC plant biology 20100101 |
Recent advances in the treatment of acute myeloid leukemia. | F1000 medicine reports 20100101 |
Molecular and therapeutic potential and toxicity of valproic acid. | Journal of biomedicine & biotechnology 20100101 |
L1CAM expression in endometrial carcinomas is regulated by usage of two different promoter regions. | BMC molecular biology 20100101 |
DNA methylation patterns provide insight into epigenetic regulation in the Pacific oyster (Crassostrea gigas). | BMC genomics 20100101 |
MicroRNA expression in human retinal pigment epithelial (ARPE-19) cells: increased expression of microRNA-9 by N-(4-hydroxyphenyl)retinamide. | Molecular vision 20100101 |
Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine. | PloS one 20100101 |
Epigenetics of renal cell carcinoma: the path towards new diagnostics and therapeutics. | Genome medicine 20100101 |
Ferroportin and erythroid cells: an update. | Advances in hematology 20100101 |
Epigenetic approaches in the treatment of myelodysplastic syndromes: clinical utility of azacitidine. | OncoTargets and therapy 20100101 |
Transcriptome and expression profiling analysis revealed changes of multiple signaling pathways involved in immunity in the large yellow croaker during Aeromonas hydrophila infection. | BMC genomics 20100101 |
A phase I biological study of azacitidine (Vidaza™) to determine the optimal dose to inhibit DNA methylation. | Epigenetics 20100101 |
Epigenetic modifiers are necessary but not sufficient for reprogramming non-myelinating cells into myelin gene-expressing cells. | PloS one 20100101 |
DNA methylation and cancer. | Advances in genetics 20100101 |
Equitoxic doses of 5-azacytidine and 5-aza-2'deoxycytidine induce diverse immediate and overlapping heritable changes in the transcriptome. | PloS one 20100101 |
Chromatin-modifying agents increase transcription of CYP46A1, a key player in brain cholesterol elimination. | Journal of Alzheimer's disease : JAD 20100101 |
S110, a novel decitabine dinucleotide, increases fetal hemoglobin levels in baboons (P. anubis). | Journal of translational medicine 20100101 |
Cell line-dependent variability in HIV activation employing DNMT inhibitors. | Virology journal 20100101 |
Recent advances in diagnosis and treatment of chronic myeloproliferative neoplasms. | F1000 medicine reports 20100101 |
Safety and efficacy of azacitidine in myelodysplastic syndromes. | Drug design, development and therapy 20100101 |
The effect of differentiating and apoptotic agents on notch signalling pathway in hepatoblastoma. | Hepato-gastroenterology 20100101 |
TFPI-2 is a putative tumor suppressor gene frequently inactivated by promoter hypermethylation in nasopharyngeal carcinoma. | BMC cancer 20100101 |
PPARγ downregulation by TGFß in fibroblast and impaired expression and function in systemic sclerosis: a novel mechanism for progressive fibrogenesis. | PloS one 20100101 |
Down-regulation of serum/glucocorticoid regulated kinase 1 in colorectal tumours is largely independent of promoter hypermethylation. | PloS one 20100101 |
Effects of valproic acid on the cell cycle and apoptosis through acetylation of histone and tubulin in a scirrhous gastric cancer cell line. | Journal of experimental & clinical cancer research : CR 20100101 |
Epigenetic control of the basal-like gene expression profile via Interleukin-6 in breast cancer cells. | Molecular cancer 20100101 |
Ex vivo development, expansion and in vivo analysis of a novel lineage of dendritic cells from hematopoietic stem cells. | Journal of immune based therapies and vaccines 20100101 |
Biological rationale for the use of DNA methyltransferase inhibitors as new strategy for modulation of tumor response to chemotherapy and radiation. | Molecular cancer 20100101 |
Reactivating aberrantly hypermethylated p15 gene in leukemic T cells by a phenylhexyl isothiocyanate mediated inter-active mechanism on DNA and chromatin. | Journal of hematology & oncology 20100101 |
Epigenetic regulation of CD133 and tumorigenicity of CD133 positive and negative endometrial cancer cells. | Reproductive biology and endocrinology : RB&E 20100101 |
Gemcitabine functions epigenetically by inhibiting repair mediated DNA demethylation. | PloS one 20100101 |
Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase. | BMC cancer 20100101 |
Characterization of a 5-azacytidine-induced developmental Aspergillus fumigatus variant. | Virulence 20100101 |
Epigenomics in cancer management. | Cancer management and research 20100101 |
Selected pharmacokinetic issues of the use of antiepileptic drugs and parenteral nutrition in critically ill patients. | Nutrition journal 20100101 |
Early Detection of t(8;21) Chromosomal Translocations During Treatment of PML-RARA Positive Acute Promyelocytic Leukemia: A Case Study. | Clinical Medicine Insights. Oncology 20100101 |
How much? How frequent? How long? A clinical guide to new therapies in myelodysplastic syndromes. | Hematology. American Society of Hematology. Education Program 20100101 |
Creating transplant tolerance by taming adverse intragraft innate immunity. | F1000 biology reports 20100101 |
Dose-modified lenalidomide induces sustained hematological response in patients with intermediate to high risk myelodysplasia. | Mediterranean journal of hematology and infectious diseases 20100101 |
Role and timing of hematopoietic cell transplantation for myelodysplastic syndrome. | Mediterranean journal of hematology and infectious diseases 20100101 |
New treatments for myelodysplastic syndromes. | Mediterranean journal of hematology and infectious diseases 20100101 |
Epigenetic regulation of wnt pathway antagonists in human glioblastoma multiforme. | Genes & cancer 20100101 |
Rationale for Targeting CD6 as a Treatment for Autoimmune Diseases. | Arthritis 20100101 |
Stem cells: An overview with respect to cardiovascular and renal disease. | Journal of natural science, biology, and medicine 20100101 |
Myelodysplastic syndromes/neoplasms: recent classification system based on World Health Organization Classification of Tumors - International Agency for Research on Cancer for Hematopoietic and Lymphoid Tissues. | Journal of blood medicine 20100101 |
Molecular basis of Mammalian embryonic stem cell pluripotency and self-renewal. | Acta naturae 20100101 |
Distinct roles of glycogen synthase kinase (GSK)-3alpha and GSK-3beta in mediating cardiomyocyte differentiation in murine bone marrow-derived mesenchymal stem cells. | The Journal of biological chemistry 20091225 |
Impact of DNA demethylation of the G0S2 gene on the transcription of G0S2 in squamous lung cancer cell lines with or without nuclear receptor agonists. | Biochemical and biophysical research communications 20091225 |
5-Azacytidine prevents cisplatin induced nephrotoxicity and potentiates anticancer activity of cisplatin by involving inhibition of metallothionein, pAKT and DNMT1 expression in chemical induced cancer rats. | Toxicology letters 20091215 |
Superior outcome with hypomethylating therapy in patients with acute myeloid leukemia and high-risk myelodysplastic syndrome and chromosome 5 and 7 abnormalities. | Cancer 20091215 |
High DNA methyltransferase 3B expression mediates 5-aza-deoxycytidine hypersensitivity in testicular germ cell tumors. | Cancer research 20091215 |
Characterization of azacytidine/poly(L-lactic) acid particles prepared by supercritical antisolvent precipitation. | Journal of pharmaceutical and biomedical analysis 20091205 |
Escape mechanisms from antibody therapy to lymphoma cells: downregulation of CD20 mRNA by recruitment of the HDAC complex and not by DNA methylation. | Biochemical and biophysical research communications 20091204 |
Undifferentiated hematopoietic cells are characterized by a genome-wide undermethylation dip around the transcription start site and a hierarchical epigenetic plasticity. | Blood 20091203 |
Regulated expression of CCL21 in the prostate tumor microenvironment inhibits tumor growth and metastasis in an orthotopic model of prostate cancer. | Cancer microenvironment : official journal of the International Cancer Microenvironment Society 20091201 |
Epigenetic modifications: new therapeutic targets in primary myelofibrosis. | Current stem cell research & therapy 20091201 |
Epigenetic regulation of microRNA expression in colorectal cancer. | International journal of cancer 20091201 |
DNA methylation regulates constitutive expression of Stat6 regulatory genes SOCS-1 and SHP-1 in colon cancer cells. | Journal of cancer research and clinical oncology 20091201 |
Involvement of DNA hypermethylation in down-regulation of the zinc transporter ZIP8 in cadmium-resistant metallothionein-null cells. | Toxicology and applied pharmacology 20091201 |
Isolation of cancer-specific chimeric transcripts induced by hypomethylation of the LINE-1 antisense promoter. | Genomics 20091201 |
Preventing autoimmunity by regulating regulatory T-cell induction. | Journal of molecular medicine (Berlin, Germany) 20091201 |
Effect of 5-azacytidine induction duration on differentiation of human first-trimester fetal mesenchymal stem cells towards cardiomyocyte-like cells. | Interactive cardiovascular and thoracic surgery 20091201 |
Induction of Foxp3 demethylation increases regulatory CD4+CD25+ T cells and prevents the occurrence of diabetes in mice. | Journal of molecular medicine (Berlin, Germany) 20091201 |
Defective interleukin-4/Stat6 activity correlates with increased constitutive expression of negative regulators SOCS-3, SOCS-7, and CISH in colon cancer cells. | Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20091201 |
Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells. | Molecular cancer therapeutics 20091201 |
Novel oligoamine analogues inhibit lysine-specific demethylase 1 and induce reexpression of epigenetically silenced genes. | Clinical cancer research : an official journal of the American Association for Cancer Research 20091201 |
DNA hypomethylation in rheumatoid arthritis synovial fibroblasts. | Arthritis and rheumatism 20091201 |
Mechanism of DNA replication-dependent transcriptional activation of the acetylcholinesterase gene in the Ciona intestinalis embryo. | Development, growth & differentiation 20091201 |
A DNA methyltransferase inhibitor and all-trans retinoic acid reduce oral cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide. | Cancer prevention research (Philadelphia, Pa.) 20091201 |
Decitabine treatment of patients with higher-risk myelodysplastic syndromes. | Leukemia research 20091201 |
Hypomethylating agents in myelodysplastic syndromes changing the inevitable: the value of azacitidine as maintenance therapy, effects on transfusion and combination with other agents. | Leukemia research 20091201 |
In vitro basis for treatment with hypomethylating agents and histone deacetylase inhibitors: can epigenetic changes be used to monitor treatment? | Leukemia research 20091201 |
Azacitidine in lower-risk myelodysplastic syndromes. | Leukemia research 20091201 |
Review of azacitidine trials in Intermediate-2-and High-risk myelodysplastic syndromes. | Leukemia research 20091201 |
Epigenetic silencing of CRABP2 and MX1 in head and neck tumors. | Neoplasia (New York, N.Y.) 20091201 |
Chemotherapeutic drug-induced ABCG2 promoter demethylation as a novel mechanism of acquired multidrug resistance. | Neoplasia (New York, N.Y.) 20091201 |
Skeletal muscle-derived stem cells exhibit cardiocyte competences. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20091201 |
The human retinoblastoma gene is imprinted. | PLoS genetics 20091201 |
Methods in DNA methylation profiling. | Epigenomics 20091201 |
LARG at chromosome 11q23 has functional characteristics of a tumor suppressor in human breast and colorectal cancer. | Oncogene 20091126 |
Decitabine, differently from DNMT1 silencing, exerts its antiproliferative activity through p21 upregulation in malignant pleural mesothelioma (MPM) cells. | Lung cancer (Amsterdam, Netherlands) 20091101 |
Repeated responses of an elderly patient with high-risk myelodysplastic syndrome to sequential therapy with tipifarnib, 5-azacitidine, and decitabine. | Annals of hematology 20091101 |
Non-intensive treatment with low-dose 5-aza-2'-deoxycytidine (DAC) prior to allogeneic blood SCT of older MDS/AML patients. | Bone marrow transplantation 20091101 |
Three epigenetic drugs up-regulate homeobox gene Rhox5 in cancer cells through overlapping and distinct molecular mechanisms. | Molecular pharmacology 20091101 |
5-Azacytidine can induce lethal mutagenesis in human immunodeficiency virus type 1. | Journal of virology 20091101 |
Generation and characterization of functional cardiomyocytes using induced pluripotent stem cells derived from human fibroblasts. | Cell biology international 20091101 |
Promoter histone H3 lysine 9 di-methylation is associated with DNA methylation and aberrant expression of p16 in gastric cancer cells. | Oncology reports 20091101 |
Epigenetic modulation of PTEN expression during antiandrogenic therapies in human prostate cancer. | International journal of oncology 20091101 |
Regulation of EP receptors in non-small cell lung cancer by epigenetic modifications. | European journal of cancer (Oxford, England : 1990) 20091101 |
DNA demethylation at specific CpG sites in the IL1B promoter in response to inflammatory cytokines in human articular chondrocytes. | Arthritis and rheumatism 20091101 |
Gammaherpesvirus-driven plasma cell differentiation regulates virus reactivation from latently infected B lymphocytes. | PLoS pathogens 20091101 |
Frequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms' tumor. | PLoS genetics 20091101 |
Tumor cell growth inhibition and cell differentiation analysis in a canine mammary tumor cell line (MCM-B2) treated with four chemical reagents. | The Journal of veterinary medical science 20091101 |
Myelodysplastic syndromes: emerging therapies, survival, and alternative outcomes. | Managed care (Langhorne, Pa.) 20091101 |
Alternative dosing schedules for methylation inhibitors in MDS treatment. | Managed care (Langhorne, Pa.) 20091101 |
Myelodysplastic syndromes: health care management considerations. | Managed care (Langhorne, Pa.) 20091101 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20091101 |
Repression of induced apoptosis in the 2-cell bovine embryo involves DNA methylation and histone deacetylation. | Biochemical and biophysical research communications 20091016 |
Suberoylanilide hydroxamic acid promotes cardiomyocyte differentiation of rat mesenchymal stem cells. | Experimental cell research 20091015 |
MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation. | Blood 20091015 |
Azacytidine inhibits RNA methylation at DNMT2 target sites in human cancer cell lines. | Cancer research 20091015 |
Alteration of transcriptional profile in human bronchial epithelial cells induced by cigarette smoke condensate. | Toxicology letters 20091008 |
Epigenetic therapies move into new territory, but how exactly do they work? | Journal of the National Cancer Institute 20091007 |
Homologous recombination but not nucleotide excision repair plays a pivotal role in tolerance of DNA-protein cross-links in mammalian cells. | The Journal of biological chemistry 20091002 |
DNA methylation and methyl-CpG binding proteins: developmental requirements and function. | Chromosoma 20091001 |
Direct effect of cocaine on epigenetic regulation of PKCepsilon gene repression in the fetal rat heart. | Journal of molecular and cellular cardiology 20091001 |
IL-17 stimulates the proliferation and differentiation of human mesenchymal stem cells: implications for bone remodeling. | Cell death and differentiation 20091001 |
Transcriptional activation of the gamma-globin gene in baboons treated with decitabine and in cultured erythroid progenitor cells involves different mechanisms. | Experimental hematology 20091001 |
Inactive X chromosome-specific reduction in placental DNA methylation. | Human molecular genetics 20091001 |
Glyceraldehyde 3-phosphate dehydrogenase depletion induces cell cycle arrest and resistance to antimetabolites in human carcinoma cell lines. | The Journal of pharmacology and experimental therapeutics 20091001 |
Relationship between methylation status of ERCC1 promoter and radiosensitivity in glioma cell lines. | Cell biology international 20091001 |
Methylation-associated silencing of S100A4 expression in human epidermal cancers. | Experimental dermatology 20091001 |
Atypical presentations of Sweet's syndrome in patients with MDS/AML receiving combinations of hypomethylating agents with histone deacetylase inhibitors. | American journal of hematology 20091001 |
Correction of the abnormal trafficking of primary myelofibrosis CD34+ cells by treatment with chromatin-modifying agents. | Cancer research 20091001 |
Development of a novel output value for quantitative assessment in methylated DNA immunoprecipitation-CpG island microarray analysis. | DNA research : an international journal for rapid publication of reports on genes and genomes 20091001 |
Fluorescence polarization combined capillary electrophoresis immunoassay for the sensitive detection of genomic DNA methylation. | Analytical chemistry 20091001 |
A phase I dose-finding study of 5-azacytidine in combination with sodium phenylbutyrate in patients with refractory solid tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20091001 |
Parathyroid hormone 1-34 inhibits terminal differentiation of human articular chondrocytes and osteoarthritis progression in rats. | Arthritis and rheumatism 20091001 |
Human T-cell leukemia virus type I-mediated repression of PDZ-LIM domain-containing protein 2 involves DNA methylation but independent of the viral oncoprotein tax. | Neoplasia (New York, N.Y.) 20091001 |
[Management of anemia and bone marrow hypoplasia in the treatment of myeloid leukemia]. | Nihon rinsho. Japanese journal of clinical medicine 20091001 |
[Novel therapeutic agents for myelodysplastic syndrome]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20091001 |
Enhancing survival outcomes in the management of patients with higher-risk myelodysplastic syndromes. | Cancer control : journal of the Moffitt Cancer Center 20091001 |
Reduction of phosphoinositide-phospholipase C beta1 methylation predicts the responsiveness to azacitidine in high-risk MDS. | Proceedings of the National Academy of Sciences of the United States of America 20090929 |
Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies. | Blood 20090924 |
DNA (Cytosine-C5) methyltransferase inhibition by oligodeoxyribonucleotides containing 2-(1H)-pyrimidinone (zebularine aglycon) at the enzymatic target site. | Biochemical pharmacology 20090915 |
Wnt antagonist gene DKK2 is epigenetically silenced and inhibits renal cancer progression through apoptotic and cell cycle pathways. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090915 |
Case records of the Massachusetts General Hospital. Case 28-2009. A 68-year-old man with fatigue, cough, and peripheral-blood monocytosis. | The New England journal of medicine 20090910 |
Decitabine-induced effusions. | Leukemia research 20090901 |
Wnt signaling pathway is epigenetically regulated by methylation of Wnt antagonists in acute myeloid leukemia. | Leukemia 20090901 |
Blockade of MEK signaling potentiates 5-Aza-2'-deoxycytidine-induced apoptosis and upregulation of p21(waf1) in acute myelogenous leukemia cells. | International journal of cancer 20090901 |
c-Myc regulates the coordinated transcription of brain disease-related PDCD10-SERPINI1 bidirectional gene pair. | Molecular and cellular neurosciences 20090901 |
Expression level and DNA methylation status of glutathione-S-transferase genes in normal murine prostate and TRAMP tumors. | The Prostate 20090901 |
Functional neurons and melanocytes induced from immortal lines of postnatal neural crest-like stem cells. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090901 |
Human cardiac mesoangioblasts isolated from hypertrophic cardiomyopathies are greatly reduced in proliferation and differentiation potency. | Cardiovascular research 20090901 |
Cord blood stem cell expansion is permissive to epigenetic regulation and environmental cues. | Experimental hematology 20090901 |
Chemical induction of silent biosynthetic pathway transcription in Aspergillus niger. | Journal of industrial microbiology & biotechnology 20090901 |
Simultaneous PKC and cAMP activation induces differentiation of human dental pulp stem cells into functionally active neurons. | Neurochemistry international 20090901 |
A phase II study of 5-day intravenous azacitidine in patients with myelodysplastic syndromes. | American journal of hematology 20090901 |
Decitabine combined with fractionated gemtuzumab ozogamicin therapy in patients with relapsed or refractory acute myeloid leukemia. | American journal of hematology 20090901 |
Neutrophilic panniculitis associated with myelodysplastic syndrome with abnormal nuclear forms. | Journal of cutaneous pathology 20090901 |
Epigenetic silencing of death receptor 4 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in gliomas. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090901 |
Hematology: Azacitidine improves survival in myelodysplastic syndromes. | Nature reviews. Clinical oncology 20090901 |
A 64-year-old male with fever and persistent lung infiltrate. | Respiratory care 20090901 |
[Effect of 5-Aza-dC on FHIT gene expression in hepatocellular carcinoma cell line HepG2]. | Ai zheng = Aizheng = Chinese journal of cancer 20090901 |
[Effects of 5-Aza-2'-deoxycytidine and trichostatin A on P16, hMLH1 and MGMT genes and DNA methylation in human gastric cancer cells]. | Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20090901 |
[Reversion transcriptional expression of DAPK in bladder cancer T24 cells 5-aza-2'-deoxycytidine]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090901 |
[Up-regulation of major histocompatibility complex class I-related molecules A (MICA) induced by 5-aza-2'-deoxycytidine]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090901 |
In vitro myogenic differentiation of human bone marrow-derived mesenchymal stem cells as a potential treatment for urethral sphincter muscle repair. | Annals of the New York Academy of Sciences 20090901 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20090901 |
[Traditional medicine CDP and promoter demethylation in breast cancer cell lines]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20090901 |
Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signalling. | Journal of cellular and molecular medicine 20090901 |
Distribution and sequence of pyknotic cells in rat fetuses exposed to busulfan. | Journal of toxicologic pathology 20090901 |
Epigenetic cross-talk between DNA methylation and histone modifications in human cancers. | Yonsei medical journal 20090831 |
Loss of human ribosomal gene CpG methylation enhances cryptic RNA polymerase II transcription and disrupts ribosomal RNA processing. | Molecular cell 20090828 |
Dynamic changes in DNA methylation during multistep rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine. | Toxicology letters 20090825 |
Effect of human umbilical cord blood cells on Ang-II-induced hypertrophy in mice. | Biochemical and biophysical research communications 20090821 |
Quantification of regional DNA methylation by liquid chromatography/tandem mass spectrometry. | Analytical biochemistry 20090815 |
The transcription factor RFX protects MHC class II genes against epigenetic silencing by DNA methylation. | Journal of immunology (Baltimore, Md. : 1950) 20090815 |
Re-differentiation of thyroid carcinoma cell lines treated with 5-Aza-2'-deoxycytidine and retinoic acid. | Molecular and cellular endocrinology 20090813 |
Multicenter study of decitabine administered daily for 5 days every 4 weeks to adults with myelodysplastic syndromes: the alternative dosing for outpatient treatment (ADOPT) trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090810 |
Frequent loss of cystatin E/M expression implicated in the progression of prostate cancer. | Oncogene 20090806 |
Promoter CpG methylation of oestrogen receptors in leukaemia. | Bioscience reports 20090801 |
5-Aza-2'-deoxycytidine reactivates expression of RUNX3 by deletion of DNA methyltransferases leading to caspase independent apoptosis in colorectal cancer Lovo cells. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090801 |
The property of methylated APC gene promotor and its influence on lung cancer cell line. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090801 |
DNA hypomethylation as Achilles' heel of tumorigenesis: a working hypothesis. | Cell biology international 20090801 |
Cardiac potential of stem cells from whole human umbilical cord tissue. | Journal of cellular biochemistry 20090801 |
Valproic acid at therapeutic plasma levels may increase 5-azacytidine efficacy in higher risk myelodysplastic syndromes. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090801 |
iTRAQ-coupled 2-D LC-MS/MS analysis of protein profile associated with HBV-modulated DNA methylation. | Proteomics 20090801 |
RUNX3 gene methylation in epithelial ovarian cancer tissues and ovarian cancer cell lines. | Omics : a journal of integrative biology 20090801 |
Methylation mediated silencing of TMS1 in breast cancer and its potential contribution to docetaxel cytotoxicity. | Anticancer research 20090801 |
Effects of 5-Aza-CdR on the proliferation of human breast cancer cell line MCF-7 and on the expression of Apaf-1 gene. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20090801 |
[Effect of demethylating treatment on cytotoxicity of NK-92MI cells]. | Zhongguo shi yan xue ye xue za zhi 20090801 |
Evolving strategies in the treatment of MDS and AML. | Clinical advances in hematology & oncology : H&O 20090801 |
Potential of DNMT and its Epigenetic Regulation for Lung Cancer Therapy. | Current genomics 20090801 |
Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells. | Oncogene 20090730 |
Proliferating cell nuclear antigen is protected from degradation by forming a complex with MutT Homolog2. | The Journal of biological chemistry 20090717 |
Lysyl oxidase-like 2 promotes migration in noninvasive breast cancer cells but not in normal breast epithelial cells. | International journal of cancer 20090715 |
Xenoestrogen-induced epigenetic repression of microRNA-9-3 in breast epithelial cells. | Cancer research 20090715 |
15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090715 |
Treatment with demethylating agent, 5-aza-2'-deoxycytidine enhances therapeutic HPV DNA vaccine potency. | Vaccine 20090709 |
Human neonatal thymus-derived mesenchymal stromal cells: characterization, differentiation, and immunomodulatory properties. | Tissue engineering. Part A 20090701 |
Assessment of ATRX expression in patients with myelodysplastic syndromes treated with decitabine. | Leukemia research 20090701 |
Aberrant expression of TSC2 gene in the newly diagnosed acute leukemia. | Leukemia research 20090701 |
Successful induction therapy with decitabine in refractory childhood acute lymphoblastic leukemia. | Leukemia 20090701 |
Epigenetic down-regulation of BIM expression is associated with reduced optimal responses to imatinib treatment in chronic myeloid leukaemia. | European journal of cancer (Oxford, England : 1990) 20090701 |
Automated quantification of DNA demethylation effects in cells via 3D mapping of nuclear signatures and population homogeneity assessment. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20090701 |
Epigenetic silencing of TTF-1/NKX2-1 through DNA hypermethylation and histone H3 modulation in thyroid carcinomas. | Laboratory investigation; a journal of technical methods and pathology 20090701 |
Epigenetic mechanisms of irinotecan sensitivity in colorectal cancer cell lines. | Molecular cancer therapeutics 20090701 |
Genomic screening for genes silenced by DNA methylation revealed an association between RASD1 inactivation and dexamethasone resistance in multiple myeloma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090701 |
Azacitidine for the treatment of myelodysplastic syndrome. | Expert review of anticancer therapy 20090701 |
Specific loss of histone H3 lysine 9 trimethylation and HP1gamma/cohesin binding at D4Z4 repeats is associated with facioscapulohumeral dystrophy (FSHD). | PLoS genetics 20090701 |
Global analysis of DNA methylation and transcription of human repetitive sequences. | Epigenetics 20090701 |
S-Adenosylhomocysteine increases beta-amyloid formation in BV-2 microglial cells by increased expressions of beta-amyloid precursor protein and presenilin 1 and by hypomethylation of these gene promoters. | Neurotoxicology 20090701 |
Clinical roundtable monograph. Overall survival and maintenance of MDS patients. | Clinical advances in hematology & oncology : H&O 20090701 |
Clinical roundtable monograph. Choosing an appropriate therapy for lower-risk MDS in the community setting. | Clinical advances in hematology & oncology : H&O 20090701 |
Clinical roundtable monograph. Combination therapies for MDS. | Clinical advances in hematology & oncology : H&O 20090701 |
[Effects of 5-aza-2'-deoxycytidine on the amount of exosomes and secreted immuno-associated proteins by hepatoma cells]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20090701 |
[E-cadherin promoter methylation and demethylation in epithelial ovarian carcinoma cells]. | Zhonghua fu chan ke za zhi 20090701 |
Promoter methylation in the genesis of gastrointestinal cancer. | Yonsei medical journal 20090630 |
Epigenetic regulation of cytokine gene expression in T lymphocytes. | Yonsei medical journal 20090630 |
How I treat patients with myelodysplastic syndromes. | Blood 20090618 |
Epigenetic modifiers: basic understanding and clinical development. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090615 |
Targeting DNA methylation. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090615 |
Synergy of 5-aza-2'-deoxycytidine (DAC) and paclitaxel in both androgen-dependent and -independent prostate cancer cell lines. | Cancer letters 20090608 |
Fetal Hemoglobin Inducers from the Natural World: A Novel Approach for Identification of Drugs for the Treatment of {beta}-Thalassemia and Sickle-Cell Anemia. | Evidence-based complementary and alternative medicine : eCAM 20090601 |
Epigenetic control of differential expression of specific ERG isoforms in acute T-lymphoblastic leukemia. | Leukemia research 20090601 |
Feasibility of allo-SCT after hypomethylating therapy with decitabine for myelodysplastic syndrome. | Bone marrow transplantation 20090601 |
Azacitidine improves antitumor effects of docetaxel and cisplatin in aggressive prostate cancer models. | Endocrine-related cancer 20090601 |
The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells. | Leukemia 20090601 |
Combined inhibition of Dnmt and mTOR signaling inhibits formation and growth of colorectal cancer. | International journal of colorectal disease 20090601 |
Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21. | Carcinogenesis 20090601 |
Demethylating treatment suppresses natural killer cell cytolytic activity. | Molecular immunology 20090601 |
CpG hypermethylation of collagen type I alpha 2 contributes to proliferation and migration activity of human bladder cancer. | International journal of oncology 20090601 |
Therapy related CMML: a case report and review of the literature. | International journal of hematology 20090601 |
The methylation of the TSC2 promoter underlies the abnormal growth of TSC2 angiomyolipoma-derived smooth muscle cells. | The American journal of pathology 20090601 |
Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090601 |
Decitabine effect on tumor global DNA methylation and other parameters in a phase I trial in refractory solid tumors and lymphomas. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090601 |
Dynamic chromatin remodeling events in hippocampal neurons are associated with NMDA receptor-mediated activation of Bdnf gene promoter 1. | Journal of neurochemistry 20090601 |
Chemical decomposition of 5-aza-2'-deoxycytidine (Decitabine): kinetic analyses and identification of products by NMR, HPLC, and mass spectrometry. | Chemical research in toxicology 20090601 |
Camptothecin-induced cell proliferation inhibition and apoptosis enhanced by DNA methyltransferase inhibitor, 5-aza-2'-deoxycytidine. | Biological & pharmaceutical bulletin 20090601 |
Disseminated varicella-zoster virus infection following azacitidine in a patient with myelodysplastic syndrome. | Clinical journal of oncology nursing 20090601 |
DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation. | Molecular cancer therapeutics 20090601 |
Epigenetic modifiers exacerbate oxidative stress in renal proximal tubule cells. | Anticancer research 20090601 |
Distinct roles for histone methyltransferases G9a and GLP in cancer germ-line antigen gene regulation in human cancer cells and murine embryonic stem cells. | Molecular cancer research : MCR 20090601 |
Use of epigenetic modification to induce FOXP3 expression in naïve T cells. | Transplantation proceedings 20090601 |
Preliminary study on 5-azacytidine anti-myeloma activity in vitro. | Zhongguo shi yan xue ye xue za zhi 20090601 |
[Effect of demethylation treatment on the expression of inhibitory receptor KIR gene in NK-92MI cell line]. | Zhongguo shi yan xue ye xue za zhi 20090601 |
Epigenetic regulation of HIV-1 latency by cytosine methylation. | PLoS pathogens 20090601 |
Epstein-barr virus latency in B cells leads to epigenetic repression and CpG methylation of the tumour suppressor gene Bim. | PLoS pathogens 20090601 |
[Detection of O6-methylguanine-DNA methyltransferase promoter methylation in chemotherapy for glioma]. | Ai zheng = Aizheng = Chinese journal of cancer 20090601 |
Epigenetic DNA-(cytosine-5-carbon) modifications: 5-aza-2'-deoxycytidine and DNA-demethylation. | Biochemistry. Biokhimiia 20090601 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20090601 |
Clinical implications of gene expression profiling in myelodysplastic syndromes: recognition of ribosomal and translational gene dysregulation and development of predictive assays. | Best practice & research. Clinical haematology 20090601 |
Treatment of chronic lymphocytic leukemia with a hypomethylating agent induces expression of NXF2, an immunogenic cancer testis antigen. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090515 |
A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation. | Cancer research 20090515 |
DNA methylation inhibits p53-mediated survivin repression. | Oncogene 20090514 |
Differential expression of stromal cell-derived factor 1 in human brain microvascular endothelial cells and pericytes involves histone modifications. | Biochemical and biophysical research communications 20090508 |
Induction of iodide uptake in transformed thyrocytes: a compound screening in cell lines. | European journal of nuclear medicine and molecular imaging 20090501 |
The developmental potential of mouse somatic cell nuclear-transferred oocytes treated with trichostatin A and 5-aza-2'-deoxycytidine. | Zygote (Cambridge, England) 20090501 |
DNA demethylation protects from cleavable complex stabilization and DNA strand breakage induced by the topoisomerase type I inhibitor camptothecin. | Mutagenesis 20090501 |
Modulation of DNA methylation by a sesquiterpene lactone parthenolide. | The Journal of pharmacology and experimental therapeutics 20090501 |
5-AZA-2'-deoxycytidine (5-AZA-CdR) leads to down-regulation of Dnmt1o and gene expression in preimplantation mouse embryos. | Zygote (Cambridge, England) 20090501 |
Low-dose azacitidine after allogeneic stem cell transplantation for acute leukemia. | Cancer 20090501 |
The comet assay: a sensitive method for detecting DNA damage in individual cells. | Methods (San Diego, Calif.) 20090501 |
Panobinostat treatment depletes EZH2 and DNMT1 levels and enhances decitabine mediated de-repression of JunB and loss of survival of human acute leukemia cells. | Cancer biology & therapy 20090501 |
Epigenetic reversal of acquired resistance to 5-fluorouracil treatment. | Molecular cancer therapeutics 20090501 |
Inhibitors of poly ADP-ribose polymerase (PARP) induce apoptosis of myeloid leukemic cells: potential for therapy of myeloid leukemia and myelodysplastic syndromes. | Haematologica 20090501 |
Epigenetic hierarchy governing Nestin expression. | Stem cells (Dayton, Ohio) 20090501 |
Additive effects of 5-aza-2'-deoxycytidine and irradiation on clonogenic survival of human medulloblastoma cell lines. | Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20090501 |
T-lymphocyte maturation-associated protein gene as a candidate metastasis suppressor for head and neck squamous cell carcinomas. | Cancer science 20090501 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20090501 |
Enhanced cardiomyogenic differentiation of P19 embryonal carcinoma stem cells. | Korean circulation journal 20090501 |
Myc sensitizes p53-deficient cancer cells to the DNA-damaging effects of the DNA methyltransferase inhibitor decitabine. | Blood 20090430 |
[The empirical study in transplantation of bone marrow mesenchymal stem cells for acute myocardial infarction]. | Zhonghua yi xue za zhi 20090421 |
Cardiomyogenic differentiation potential of human adipose precursor cells. | International journal of cardiology 20090417 |
Hematologic response to three alternative dosing schedules of azacitidine in patients with myelodysplastic syndromes. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090410 |
Epigenetic silencing of EphA1 expression in colorectal cancer is correlated with poor survival. | British journal of cancer 20090407 |
Treatment of ovarian cancer cell lines with 5-aza-2'-deoxycytidine upregulates the expression of cancer-testis antigens and class I major histocompatibility complex-encoded molecules. | Cancer immunology, immunotherapy : CII 20090401 |
Demethylating agent 5-aza-2'-deoxycytidine activates HLA-G expression in human leukemia cell lines. | Leukemia research 20090401 |
Methylation of the OP-1 promoter: potential role in the age-related decline in OP-1 expression in cartilage. | Osteoarthritis and cartilage 20090401 |
Decitabine is an effective treatment of idiopathic myelofibrosis. | British journal of haematology 20090401 |
Stem-cell-like glioma cells are resistant to TRAIL/Apo2L and exhibit down-regulation of caspase-8 by promoter methylation. | Acta neuropathologica 20090401 |
BTG3 tumor suppressor gene promoter demethylation, histone modification and cell cycle arrest by genistein in renal cancer. | Carcinogenesis 20090401 |
Retroviral delivery of promoter-targeted shRNA induces long-term silencing of HIV-1 transcription. | Microbes and infection 20090401 |
The evolution of hematopoietic SCT in myelodysplastic syndrome. | Bone marrow transplantation 20090401 |
Synergistic effect of trichostatin A and 5-aza-2'-deoxycytidine on growth inhibition of pancreatic endocrine tumour cell lines: a proteomic study. | Proteomics 20090401 |
Growth inhibition of human cancer cells by 5-aza-2'-deoxycytidine does not correlate with its effects on INK4a/ARF expression or initial promoter methylation status. | Molecular cancer therapeutics 20090401 |
Durable clinical and cytogenetic remission in an elderly patient with relapsed acute myeloid leukemia treated with low-dose lenalidomide. | Leukemia & lymphoma 20090401 |
[Effect of a methylation inhibitor 5-aza-2'-deoxycytidine on SHP-1 gene expression, proliferation and apoptosis in K562 cells]. | Zhongguo shi yan xue ye xue za zhi 20090401 |
LINE-1 methylation in plasma DNA as a biomarker of activity of DNA methylation inhibitors in patients with solid tumors. | Epigenetics 20090401 |
Glucocorticoid receptor alpha and beta variant expression is associated with ASF/SF2 splicing factor upregulation in HT-29 colon cancer and MCF-7 breast carcinoma cells. | Archives of medical research 20090401 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20090401 |
[5-azacytidine treatment induces tumor suppressor gene XAF1 expression and inhibits proliferation in myeloma cells]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20090401 |
Azacitidine: activity and efficacy as an epigenetic treatment of myelodysplastic syndromes. | Expert review of hematology 20090401 |
Hypomethylating drugs convert HA-1-negative solid tumors into targets for stem cell-based immunotherapy. | Blood 20090319 |
Intriguing response to azacitidine in a patient with juvenile myelomonocytic leukemia and monosomy 7. | Blood 20090319 |
Timing is everything: order of administration of 5-aza 2' deoxycytidine, trichostatin A and tamoxifen changes estrogen receptor mRNA expression and cell sensitivity. | Cancer letters 20090318 |
6-Thioguanine perturbs cytosine methylation at the CpG dinucleotide site by DNA methyltransferases in vitro and acts as a DNA demethylating agent in vivo. | Biochemistry 20090317 |
Epigenetic regulation of c-ROS receptor tyrosine kinase expression in malignant gliomas. | Cancer research 20090315 |
Combined inhibition of DNA methylation and histone acetylation enhances gene re-expression and drug sensitivity in vivo. | British journal of cancer 20090310 |
Diet-induced up-regulation of gene expression in adipocytes without changes in DNA methylation. | The Kobe journal of medical sciences 20090310 |
A limited number of 5-azacitidine cycles can be effective treatment in MDS. | Annals of hematology 20090301 |
Complete cytogenetic remission after decitabine treatment in a patient with secondary AML harbouring high p15INK4b gene methylation and high global DNA methylation. | Annals of hematology 20090301 |
A paramutation phenomenon is involved in the genetics of maize low phytic acid1-241 (lpa1-241) trait. | Heredity 20090301 |
Epigenetic regulation of E-cadherin controls endometrial receptivity. | Endocrinology 20090301 |
Synergistic induction of NY-ESO-1 antigen expression by a novel histone deacetylase inhibitor, valproic acid, with 5-aza-2'-deoxycytidine in glioma cells. | Journal of neuro-oncology 20090301 |
Promoter methylation blocks FES protein-tyrosine kinase gene expression in colorectal cancer. | Genes, chromosomes & cancer 20090301 |
Combination of DNA methylation inhibitor 5-azacytidine and arsenic trioxide has synergistic activity in myeloma. | European journal of haematology 20090301 |
Regulation of surfactant protein B gene expression in bone marrow-derived cells. | Stem cells (Dayton, Ohio) 20090301 |
Interaction between the mismatch repair and nucleotide excision repair pathways in the prevention of 5-azacytidine-induced CG-to-GC mutations in Escherichia coli. | DNA repair 20090301 |
Characterization of autonomous Dart1 transposons belonging to the hAT superfamily in rice. | Molecular genetics and genomics : MGG 20090301 |
Differential CpG island methylation of murine adenine nucleotide translocase genes. | Biochimica et biophysica acta 20090301 |
A systematic assessment of radiation dose enhancement by 5-Aza-2'-deoxycytidine and histone deacetylase inhibitors in head-and-neck squamous cell carcinoma. | International journal of radiation oncology, biology, physics 20090301 |
Unique methylation pattern of oncostatin m receptor gene in cancers of colorectum and other digestive organs. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090301 |
Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study. | The Lancet. Oncology 20090301 |
Improving survival in myelodysplastic syndromes. | The Lancet. Oncology 20090301 |
DNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolution. | PLoS genetics 20090301 |
GSTP1 determines cis-platinum cytotoxicity in gastric adenocarcinoma MGC803 cells: regulation by promoter methylation and extracellular regulated kinase signaling. | Anti-cancer drugs 20090301 |
Optimal sequencing of treatments for patients with myelodysplastic syndromes. | Current opinion in hematology 20090301 |
Novel strategies for patients with chronic myeloproliferative disorders. | Current opinion in hematology 20090301 |
Is stem cell-based therapy going on or out for cardiac disease? | Korean circulation journal 20090301 |
Possible involvement of activation of P53/P21 and demethylation of RUNX 3 in the cytotoxicity against Lovo cells induced by 5-Aza-2'-deoxycytidine. | Life sciences 20090227 |
The context and potential of epigenetics in oncology. | British journal of cancer 20090224 |
Silencing of the CKII alpha and CKII alpha' genes during cellular senescence is mediated by DNA methylation. | Gene 20090215 |
The presence of a methylation fingerprint of Helicobacter pylori infection in human gastric mucosae. | International journal of cancer 20090215 |
Methylation-mediated repression of GADD45alpha in prostate cancer and its role as a potential therapeutic target. | Cancer research 20090215 |
Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 in human cancer cells. | Biochemical and biophysical research communications 20090213 |
Loss of MLL5 results in pleiotropic hematopoietic defects, reduced neutrophil immune function, and extreme sensitivity to DNA demethylation. | Blood 20090212 |
Inhibition of cytidine deaminase by zebularine enhances the antineoplastic action of 5-aza-2'-deoxycytidine. | Cancer chemotherapy and pharmacology 20090201 |
Progressive silencing of p14ARF in oesophageal adenocarcinoma. | Journal of cellular and molecular medicine 20090201 |
Effect of 5-azacytidine on the methylation aspects of NMDA receptor NR2B gene in the cultured cortical neurons of mice. | Neurochemical research 20090201 |
Effective, homogeneous and transient interference with cytosine methylation in plant genomic DNA by zebularine. | The Plant journal : for cell and molecular biology 20090201 |
DNA methylation inhibition increases T cell KIR expression through effects on both promoter methylation and transcription factors. | Clinical immunology (Orlando, Fla.) 20090201 |
Transcriptional activity of the novel identified human yy2 promoter is modified by DNA methylation. | Gene 20090201 |
Haemoglobin F modulation in childhood sickle cell disease. | British journal of haematology 20090201 |
Regulation of the leucocyte chemoattractant receptor FPR in glioblastoma cells by cell differentiation. | Carcinogenesis 20090201 |
Estrogen-mediated suppression of the gene encoding protein tyrosine phosphatase PTPRO in human breast cancer: mechanism and role in tamoxifen sensitivity. | Molecular endocrinology (Baltimore, Md.) 20090201 |
Azacitidine enhances sensitivity of platinum-resistant ovarian cancer cells to carboplatin through induction of apoptosis. | American journal of obstetrics and gynecology 20090201 |
The anti-leukemic effect of a novel histone deacetylase inhibitor MCT-1 and 5-aza-cytidine involves augmentation of Nur77 and inhibition of MMP-9 expression. | International journal of oncology 20090201 |
Antitumor effects of a combined 5-aza-2'deoxycytidine and valproic acid treatment on rhabdomyosarcoma and medulloblastoma in Ptch mutant mice. | Cancer research 20090201 |
Methylation status of CpG islands flanking a cAMP response element motif on the protein phosphatase 2Ac alpha promoter determines CREB binding and activity. | Journal of immunology (Baltimore, Md. : 1950) 20090201 |
Aberrant promoter methylation of SPARC in ovarian cancer. | Neoplasia (New York, N.Y.) 20090201 |
Inactivation of the MAL gene in breast cancer is a common event that predicts benefit from adjuvant chemotherapy. | Molecular cancer research : MCR 20090201 |
Timing of induction of cardiomyocyte differentiation for in vitro cultured mesenchymal stem cells: a perspective for emergencies. | Canadian journal of physiology and pharmacology 20090201 |
Androgen receptor CpG island methylation status in human leukemia cancer cells. | Cancer investigation 20090201 |
Health-related quality of life and symptom assessment in patients with myelodysplastic syndromes. | Expert review of hematology 20090201 |
Epigenetic inactivation of SLIT2 in human hepatocellular carcinomas. | Biochemical and biophysical research communications 20090130 |
Induction of cholinergic differentiation by 5-azacytidine in NG108-15 neuronal cells. | Neuroreport 20090128 |
Concepts of epigenetics in prostate cancer development. | British journal of cancer 20090127 |
Promoter CpG methylation in cancer cells contributes to the regulation of MUC4. | British journal of cancer 20090127 |
Aberrant methylation of candidate tumor suppressor genes in neuroblastoma. | Cancer letters 20090118 |
Hypoxic silencing of tumor suppressor RUNX3 by histone modification in gastric cancer cells. | Oncogene 20090115 |
Mechanisms of resistance to 5-aza-2'-deoxycytidine in human cancer cell lines. | Blood 20090115 |
Down-regulation of Rap1GAP via promoter hypermethylation promotes melanoma cell proliferation, survival, and migration. | Cancer research 20090115 |
PTPROt inactivates the oncogenic fusion protein BCR/ABL and suppresses transformation of K562 cells. | The Journal of biological chemistry 20090102 |
Deleterious CHEK2 1100delC and L303X mutants identified among 38 human breast cancer cell lines. | Breast cancer research and treatment 20090101 |
5-Azacitidine has limited therapeutic activity in myelofibrosis. | Leukemia 20090101 |
Isolation of mesenchymal stem cells (MSCs) from green fluorescent protein positive (GFP+) transgenic rodents: the grass is not always green(er). | Stem cells and development 20090101 |
Core promoter sequence of SEMG I spans between the two putative GATA-1 binding domains and is responsive to IL-4 and IL-6 in myeloma cells. | Leukemia research 20090101 |
DNA hypermethylation regulates the expression of members of the Mu-class glutathione S-transferases and glutathione peroxidases in Barrett's adenocarcinoma. | Gut 20090101 |
Identification of candidate tumor suppressor genes inactivated by promoter methylation in melanoma. | Genes, chromosomes & cancer 20090101 |
Epigenetic silencing of LRRC3B in colorectal cancer. | Scandinavian journal of gastroenterology 20090101 |
Sensitization by 5-azacytidine toward death receptor-induced hepatic apoptosis. | The Journal of pharmacology and experimental therapeutics 20090101 |
Comparative epigenomics of human and mouse mammary tumors. | Genes, chromosomes & cancer 20090101 |
Induction of intestinalization in human esophageal keratinocytes is a multistep process. | Carcinogenesis 20090101 |
Epigenetic therapy of leukemia: An update. | The international journal of biochemistry & cell biology 20090101 |
5'-azacytidine expression arrays. | Methods in molecular biology (Clifton, N.J.) 20090101 |
DNA methyltransferase inhibitor 5-aza-CdR enhances the radiosensitivity of gastric cancer cells. | Cancer science 20090101 |
Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation. | Journal of immunology (Baltimore, Md. : 1950) 20090101 |
Inhibition of DNA methyltransferase activates tumor necrosis factor alpha-induced monocytic differentiation in acute myeloid leukemia cells. | Cancer research 20090101 |
Senescence induction; a possible cancer therapy. | Molecular cancer 20090101 |
Human concentrative nucleoside transporter 1-mediated uptake of 5-azacytidine enhances DNA demethylation. | Molecular cancer therapeutics 20090101 |
[5-Aza-CdR regulates the expression of RASSF1A gene in human gastric cancer cell line and inhibits the growth of cells]. | Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20090101 |
Study of 5-Aza-CdR on transcription regulation of RASSF1A gene in the BIU87 cell line. | Urologia internationalis 20090101 |
Phenotypic instability and epigenetic variability in a diploid potato of hybrid origin, Solanum ruiz-lealii. | BMC plant biology 20090101 |
Integrative analysis of epigenetic modulation in melanoma cell response to decitabine: clinical implications. | PloS one 20090101 |
RTA promoter demethylation and histone acetylation regulation of murine gammaherpesvirus 68 reactivation. | PloS one 20090101 |
Isolation, culture and characterization of cardiac progenitor cells derived from human embryonic heart tubes. | Cells, tissues, organs 20090101 |
The characterization of DNA methylation-mediated regulation of bovine placental lactogen and bovine prolactin-related protein-1 genes. | BMC molecular biology 20090101 |
Parp1 localizes within the Dnmt1 promoter and protects its unmethylated state by its enzymatic activity. | PloS one 20090101 |
Discovery of novel hypermethylated genes in prostate cancer using genomic CpG island microarrays. | PloS one 20090101 |
Microdeletion syndromes disclose replication timing alterations of genes unrelated to the missing DNA. | Molecular cytogenetics 20090101 |
[Effects of cardiotrophin-1 on differentiation of cardiomyocyte-like cells induced from rat bone marrow mesenchymal stem cells]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20090101 |
Epigenetic modifications of the Estrogen receptor beta gene in epithelial ovarian cancer cells. | Anticancer research 20090101 |
Fenretinide-induced caspase-8 activation and apoptosis in an established model of metastatic neuroblastoma. | BMC cancer 20090101 |
Fascin-1 promoter activity is regulated by CREB and the aryl hydrocarbon receptor in human carcinoma cells. | PloS one 20090101 |
Heterochromatin protein 1 (HP1) proteins do not drive pericentromeric cohesin enrichment in human cells. | PloS one 20090101 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20090101 |
Protandim, a fundamentally new antioxidant approach in chemoprevention using mouse two-stage skin carcinogenesis as a model. | PloS one 20090101 |
Quantitation of DNA methylation by melt curve analysis. | BMC cancer 20090101 |
Epigenetic alteration of the metallothionein 1E gene in human endometrial carcinomas. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20090101 |
Challenging issues in molecular-targeted therapy. | Therapeutics and clinical risk management 20090101 |
Counteracting quasispecies adaptability: extinction of a ribavirin-resistant virus mutant by an alternative mutagenic treatment. | PloS one 20090101 |
Phase 1-2a multicenter dose-escalation study of ezatiostat hydrochloride liposomes for injection (Telintra, TLK199), a novel glutathione analog prodrug in patients with myelodysplastic syndrome. | Journal of hematology & oncology 20090101 |
Effect of c-MYC and E2F1 gene silencing and of 5-azacytidine treatment on telomerase activity in pancreatic cancer-derived cell lines. | Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20090101 |
The combination effect of sodium butyrate and 5-Aza-2'-deoxycytidine on radiosensitivity in RKO colorectal cancer and MCF-7 breast cancer cell lines. | World journal of surgical oncology 20090101 |
New clinical developments in histone deacetylase inhibitors for epigenetic therapy of cancer. | Journal of hematology & oncology 20090101 |
Targeted treatment of acute myeloid leukemia in older adults: role of gemtuzumab ozogamicin. | Clinical interventions in aging 20090101 |
Development of DNA methyltransferase inhibitors for the treatment of neoplastic diseases. | Current medicinal chemistry 20090101 |
Expression of the peroxisome proliferator activated receptor gamma gene is repressed by DNA methylation in visceral adipose tissue of mouse models of diabetes. | BMC biology 20090101 |
Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations. | Journal of translational medicine 20090101 |
Vorinostat in solid and hematologic malignancies. | Journal of hematology & oncology 20090101 |
14-3-3sigma gene silencing during melanoma progression and its role in cell cycle control and cellular senescence. | Molecular cancer 20090101 |
Cellular epigenetic modifications of neural stem cell differentiation. | Cell transplantation 20090101 |
Defining and targeting transcription factors in cancer. | Genome biology 20090101 |
Analysis of different routes of administration of heterologous 5-azacytidine-treated mesenchymal stem cells in a porcine model of myocardial infarction. | Transplantation proceedings 20090101 |
Activation of HLA-G expression by 5-aza-2 - deoxycytidine in malignant hematopoetic cells isolated from leukemia patients. | Neoplasma 20090101 |
Cyclophosphamide chemotherapy sensitizes tumor cells to TRAIL-dependent CD8 T cell-mediated immune attack resulting in suppression of tumor growth. | PloS one 20090101 |
A comprehensive microarray-based DNA methylation study of 367 hematological neoplasms. | PloS one 20090101 |
Gravity, a regulation factor in the differentiation of rat bone marrow mesenchymal stem cells. | Journal of biomedical science 20090101 |
Drugs associated with more suicidal ideations are also associated with more suicide attempts. | PloS one 20090101 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20090101 |
Expression and mutation analysis of TIG1 (tazarotene-induced gene 1) in human gastric cancer. | Oncology research 20090101 |
Real-time PCR analysis of genes encoding tumor antigens in esophageal tumors and a cancer vaccine. | Cancer immunity 20090101 |
BCL-6 oncoprotein in breast cancer: loss of expression in disease progression. | Pathobiology : journal of immunopathology, molecular and cellular biology 20090101 |
DNA copy-number loss on 1p36.1 harboring RUNX3 with promoter hypermethylation and associated loss of RUNX3 expression in liver fluke-associated intrahepatic cholangiocarcinoma. | Asian Pacific journal of cancer prevention : APJCP 20090101 |
Maternal high fat diet during pregnancy and lactation alters hepatic expression of insulin like growth factor-2 and key microRNAs in the adult offspring. | BMC genomics 20090101 |
Hypomethylation and expression of BEX2, IGSF4 and TIMP3 indicative of MLL translocations in acute myeloid leukemia. | Molecular cancer 20090101 |
Human bone marrow stem cells co-cultured with neonatal rat cardiomyocytes display limited cardiomyogenic plasticity. | Cytotherapy 20090101 |
Inhibition of myostatin promotes myogenic differentiation of rat bone marrow-derived mesenchymal stromal cells. | Cytotherapy 20090101 |
Human spongiosa mesenchymal stem cells fail to generate cardiomyocytes in vitro. | Journal of negative results in biomedicine 20090101 |
Fas expression in metastatic osteosarcoma cells is not regulated by CpG island methylation. | Oncology research 20090101 |
Azacitidine: a review of its use in higher-risk myelodysplastic syndromes/acute myeloid leukaemia. | Drugs 20090101 |
Troglitazone reverses the multiple drug resistance phenotype in cancer cells. | Drug design, development and therapy 20090101 |
Silencing of claudin-11 is associated with increased invasiveness of gastric cancer cells. | PloS one 20090101 |
Molecular control of HIV-1 postintegration latency: implications for the development of new therapeutic strategies. | Retrovirology 20090101 |
Managing myelodysplastic symptoms in elderly patients. | Clinical interventions in aging 20090101 |
Fetal globin induction in beta-thalassemia. | Hemoglobin 20090101 |
Treatment of MDS: something old, something new, something borrowed.. | Hematology. American Society of Hematology. Education Program 20090101 |
Global demethylation of rat chondrosarcoma cells after treatment with 5-aza-2'-deoxycytidine results in increased tumorigenicity. | PloS one 20090101 |
Potential impact of stress activated retrotransposons on genome evolution in a marine diatom. | BMC genomics 20090101 |
Management of myelodysplastic syndromes in the geriatric patient. | Current hematologic malignancy reports 20090101 |
Myelodysplastic syndrome: An update on diagnosis and therapy. | Current hematologic malignancy reports 20090101 |
Hematopoietic stem cell transplantation in patients with myelodysplastic syndrome. | F1000 medicine reports 20090101 |
The role of azacitidine in the management of myelodysplastic syndromes (MDS). | Cancer management and research 20090101 |
The importance of epigenetic alterations in the development of epstein-barr virus-related lymphomas. | Mediterranean journal of hematology and infectious diseases 20090101 |
EBV in Hodgkin Lymphoma. | Mediterranean journal of hematology and infectious diseases 20090101 |
Beneficial effects of population bottlenecks in an RNA virus evolving at increased error rate. | Journal of molecular biology 20081231 |
Mature adipocyte-derived dedifferentiated fat cells can transdifferentiate into skeletal myocytes in vitro. | Biochemical and biophysical research communications 20081219 |
Identification of PMF1 methylation in association with bladder cancer progression. | Clinical cancer research : an official journal of the American Association for Cancer Research 20081215 |
Methyl-CpG targeted transcriptional activation allows re-expression of tumor suppressor genes in human cancer cells. | Biochemical and biophysical research communications 20081212 |
Aberrant methylation of human L- and M-fructose 1,6-bisphosphatase genes in cancer. | Biochemical and biophysical research communications 20081212 |
Regulation of cyclin D1 and Wnt10b gene expression by cAMP-responsive element-binding protein during early adipogenesis involves differential promoter methylation. | The Journal of biological chemistry 20081212 |
Inhibition of DNA methyltransferase activity upregulates Fyn tyrosine kinase expression in Hut-78 T-lymphoma cells. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20081201 |
Semenogelin I expression in myeloma cells can be upregulated pharmacologically. | Leukemia research 20081201 |
Alleviation of myelodysplastic syndrome-associated skin rush after treatment with decitabine. | European journal of haematology 20081201 |
Predictive value of expression and promoter hypermethylation of XAF1 in hepatitis B virus-associated hepatocellular carcinoma treated with transplantation. | Annals of surgical oncology 20081201 |
Epigenetic silencing of the interferon regulatory factor ICSBP/IRF8 in human multiple myeloma. | Experimental hematology 20081201 |
Reactivation of IGFBP7 by DNA demethylation inhibits human colon cancer cell growth in vitro. | Cancer biology & therapy 20081201 |
Differentiation of human adipose-derived stem cells towards cardiomyocytes is facilitated by laminin. | Cell and tissue research 20081201 |
Aberrant methylation of ADAMTS1 in non-small cell lung cancer. | Cancer genetics and cytogenetics 20081201 |
Are new agents really making a difference in MDS? | Best practice & research. Clinical haematology 20081201 |
Epigenetic inactivation of galanin receptor 1 in head and neck cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20081201 |
In vitro effects of low-level laser irradiation for bone marrow mesenchymal stem cells: proliferation, growth factors secretion and myogenic differentiation. | Lasers in surgery and medicine 20081201 |
[Effects of 5-Aza-2'-deoxycytidine and trichostatin A on DNA methylation and expression of hMLH1 in ovarian cancer cell line COC1/DDP]. | Ai zheng = Aizheng = Chinese journal of cancer 20081201 |
Gateways to clinical trials. December 2008. | Methods and findings in experimental and clinical pharmacology 20081201 |
Recent advances in low- and intermediate-1-risk myelodysplastic syndrome: developing a consensus for optimal therapy. | Clinical advances in hematology & oncology : H&O 20081201 |
Epigenetic perturbations in the pathogenesis of mustard toxicity; hypothesis and preliminary results. | Interdisciplinary toxicology 20081201 |
Nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) expression is increased by the histone deacetylase inhibitor trichostatin A. | The Journal of biological chemistry 20081128 |
PCFT/SLC46A1 promoter methylation and restoration of gene expression in human leukemia cells. | Biochemical and biophysical research communications 20081128 |
Promoter hypermethylation of CDH13 is a common, early event in human esophageal adenocarcinogenesis and correlates with clinical risk factors. | International journal of cancer 20081115 |
p53-inducible ribonucleotide reductase (p53R2/RRM2B) is a DNA hypomethylation-independent decitabine gene target that correlates with clinical response in myelodysplastic syndrome/acute myelogenous leukemia. | Cancer research 20081115 |
Management of myelodysplastic syndromes: 2008 update. | Oncology (Williston Park, N.Y.) 20081115 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. | Journal of medicinal chemistry 20081113 |
Epigenetic mechanisms and Sp1 regulate mitochondrial citrate carrier gene expression. | Biochemical and biophysical research communications 20081107 |
Methylation of CIITA promoter IV causes loss of HLA-II inducibility by IFN-gamma in promyelocytic cells. | International immunology 20081101 |
Demethylating agents in myeloid malignancies. | Current opinion in oncology 20081101 |
PAX4 has the potential to function as a tumor suppressor in human melanoma. | International journal of oncology 20081101 |
The aberrant promoter methylation of BMP3b and BMP6 in malignant pleural mesotheliomas. | Oncology reports 20081101 |
Involvement of epigenetic mechanisms in the regulation of secreted phospholipase A2 expressions in Jurkat leukemia cells. | Neoplasia (New York, N.Y.) 20081101 |
AZGP1 autoantibody predicts survival and histone deacetylase inhibitors increase expression in lung adenocarcinoma. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20081101 |
Hydroxyurea, azacitidine and gemtuzumab ozogamicin therapy in patients with previously untreated non-M3 acute myeloid leukemia and high-risk myelodysplastic syndromes in the elderly: results from a pilot trial. | Leukemia & lymphoma 20081101 |
DNA hypomethylation therapies and hemoglobin disorders. [An interview with Hassana Fathallah by H&O]. | Clinical advances in hematology & oncology : H&O 20081101 |
New agents for the treatment of AML recent study findings. | Clinical advances in hematology & oncology : H&O 20081101 |
Future research directions for the treatment of AML. | Clinical advances in hematology & oncology : H&O 20081101 |
[The expression of GATA-4 and Nkx2.5 gene in the transformation of Rattus mesenchymal stem cells into cardiomyocytes]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20081101 |
T-2 toxin-induced toxicity in pregnant mice and rats. | International journal of molecular sciences 20081101 |
[Myelodysplastic syndromes: therapeutic advances and promising future]. | Medicina clinica 20081018 |
Role of myofibroblasts in innate chemoresistance of pancreatic carcinoma--epigenetic downregulation of caspases. | International journal of cancer 20081015 |
Promoter methylation of the bone morphogenetic protein-6 gene in association with adult T-cell leukemia. | International journal of cancer 20081015 |
Molecular and biologic characterization and drug sensitivity of pan-histone deacetylase inhibitor-resistant acute myeloid leukemia cells. | Blood 20081001 |
Promoter hypomethylation regulates CD133 expression in human gliomas. | Cell research 20081001 |
Combination of 5-azacytidine and thalidomide for the treatment of myelodysplastic syndromes and acute myeloid leukemia. | Cancer 20081001 |
Decitabine as 'bridge therapy' to a MUD transplant in relapsed AML postautologous stem cell transplantation. | American journal of hematology 20081001 |
Highly efficient regioselective synthesis of 5'-O-lauroyl-5-azacytidine catalyzed by Candida antarctica Lipase B. | Applied biochemistry and biotechnology 20081001 |
In utero supplementation with methyl donors enhances allergic airway disease in mice. | The Journal of clinical investigation 20081001 |
Changing the treatment paradigm in myelodysplastic syndromes. | Cancer control : journal of the Moffitt Cancer Center 20081001 |
Treatment strategies to optimize clinical benefit in the patient with myelodysplastic syndromes. | Cancer control : journal of the Moffitt Cancer Center 20081001 |
Future directions in myelodysplastic syndrome: newer agents and the role of combination approaches. | Cancer control : journal of the Moffitt Cancer Center 20081001 |
Histone deacetylase inhibitor scriptaid induces cell cycle arrest and epigenetic change in colon cancer cells. | International journal of oncology 20081001 |
Phase I study of epigenetic modulation with 5-azacytidine and valproic acid in patients with advanced cancers. | Clinical cancer research : an official journal of the American Association for Cancer Research 20081001 |
Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors. | Cancer research 20081001 |
[Pathogenesis of and therapeutic progress for myelodysplastic syndromes]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20081001 |
[Epigenetics in hematological disorders]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20081001 |
The costs of drugs used to treat myelodysplastic syndromes following National Comprehensive Cancer Network Guidelines. | Journal of the National Comprehensive Cancer Network : JNCCN 20081001 |
Expression and promoter methylation status of mismatch repair gene hMLH1 and hMSH2 in epithelial ovarian cancer. | The Australian & New Zealand journal of obstetrics & gynaecology 20081001 |
The high rate of endoreduplication in the repair deficient CHO mutant EM9 parallels a reduced level of methylated deoxycytidine in DNA. | Mutation research 20080926 |
[Histone H3 lysine 9 methylation is associated with the expression of hMLH1 and DNA methylation in gastric cancer cells]. | Zhonghua yi xue za zhi 20080916 |
Will histone deacetylase inhibitors require combination with other agents to fulfil their therapeutic potential? | British journal of cancer 20080902 |
Trichostatin A and 5 Aza-2' deoxycytidine decrease estrogen receptor mRNA stability in ER positive MCF7 cells through modulation of HuR. | Breast cancer research and treatment 20080901 |
Evaluation of a functional epigenetic approach to identify promoter region methylation in phaeochromocytoma and neuroblastoma. | Endocrine-related cancer 20080901 |
Deoxyribonucleic acid methyltransferase 3B promotes epigenetic silencing through histone 3 chromatin modifications in pituitary cells. | The Journal of clinical endocrinology and metabolism 20080901 |
A pilot pharmacokinetic study of oral azacitidine. | Leukemia 20080901 |
Genetic and epigenetic inactivation of T-cadherin in human hepatocellular carcinoma cells. | International journal of cancer 20080901 |
Increased pre-implantation development of cloned bovine embryos treated with 5-aza-2'-deoxycytidine and trichostatin A. | Theriogenology 20080901 |
Selection against PUMA gene expression in Myc-driven B-cell lymphomagenesis. | Molecular and cellular biology 20080901 |
Discovery of myopodin methylation in bladder cancer. | The Journal of pathology 20080901 |
Potential link between estrogen receptor-alpha gene hypomethylation and uterine fibroid formation. | Molecular human reproduction 20080901 |
LRRC3B, encoding a leucine-rich repeat-containing protein, is a putative tumor suppressor gene in gastric cancer. | Cancer research 20080901 |
Azacytidine causes complex DNA methylation responses in myeloid leukemia. | Molecular cancer therapeutics 20080901 |
Alterations of constitutive pericentromeric heterochromatin in lymphocytes of cancer patients and lymphocytes exposed to 5-azacytidine is associated with DNA-hypomethylation. | Experimental oncology 20080901 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20080901 |
Cancer prevention: epigenetics steps up to the plate. | Cancer prevention research (Philadelphia, Pa.) 20080901 |
[5-aza-2'-deoxycytidine induces changes of histone H3-lysine 9 methylation in bladder tumor cells]. | Zhonghua yi xue za zhi 20080819 |
Hypermethylation of the Keap1 gene in human lung cancer cell lines and lung cancer tissues. | Biochemical and biophysical research communications 20080815 |
2'-Deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]-5-azacytidine: a novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1. | Cancer letters 20080808 |
CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery. | The Journal of biological chemistry 20080808 |
Plasma pharmacokinetics and oral bioavailability of 3,4,5,6-tetrahydrouridine, a cytidine deaminase inhibitor, in mice. | Cancer chemotherapy and pharmacology 20080801 |
ER alpha negative breast cancer cells restore response to endocrine therapy by combination treatment with both HDAC inhibitor and DNMT inhibitor. | Journal of cancer research and clinical oncology 20080801 |
Curcumin downregulates H19 gene transcription in tumor cells. | Journal of cellular biochemistry 20080801 |
Current status of epigenetic treatment in myelodysplastic syndromes. | Annals of hematology 20080801 |
DNA methylation and histone modifications cause silencing of Wnt antagonist gene in human renal cell carcinoma cell lines. | International journal of cancer 20080801 |
Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells. | International journal of cancer 20080801 |
Epigenetic remodeling during arsenical-induced malignant transformation. | Carcinogenesis 20080801 |
Intracerebral transplantation of human adipose tissue stromal cells after middle cerebral artery occlusion in rats. | Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20080801 |
5-Azacytidine-treated human mesenchymal stem/progenitor cells derived from umbilical cord, cord blood and bone marrow do not generate cardiomyocytes in vitro at high frequencies. | Vox sanguinis 20080801 |
Epigenetic inheritance of DNA methylation limits activation-induced expression of FOXP3 in conventional human CD25-CD4+ T cells. | International immunology 20080801 |
5-Aza-2'-deoxycytidine restores proapoptotic function of p53 in cancer cells resistant to p53-induced apoptosis. | Cancer investigation 20080801 |
Azacitidine and the beginnings of therapeutic epigenetic modulation. | Expert opinion on pharmacotherapy 20080801 |
Downmodulation of dimethyl transferase activity enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in prostate cancer cells. | International journal of oncology 20080801 |
Analysis of the methylation status of genes up-regulated by the demethylating agent, 5-aza-2'-deoxycytidine, in esophageal squamous cell carcinoma. | Oncology reports 20080801 |
Epigenetic identification of ubiquitin carboxyl-terminal hydrolase L1 as a functional tumor suppressor and biomarker for hepatocellular carcinoma and other digestive tumors. | Hepatology (Baltimore, Md.) 20080801 |
Antagonism between DNA and H3K27 methylation at the imprinted Rasgrf1 locus. | PLoS genetics 20080801 |
New drugs in acute myeloid leukemia. | Seminars in oncology 20080801 |
[Effect of decitabine combined with Trichostatin A on MDS cell line SKM-1 in vitro]. | Zhongguo shi yan xue ye xue za zhi 20080801 |
Retinoic acid receptor beta2 re-expression and growth inhibition in thyroid carcinoma cell lines after 5-aza-2'-deoxycytidine treatment. | Journal of endocrinological investigation 20080801 |
Promoter hypermethylation is not the major mechanism for inactivation of the FBXW7 beta-form in human gliomas. | Genes & genetic systems 20080801 |
[Hypomethylation of 5'CpG island of insulin-like growth factor binding protein-related protein 1 is associated with its overexpression in colorectal cancer]. | Zhonghua bing li xue za zhi = Chinese journal of pathology 20080801 |
Epigenetic silencing of AXIN2/betaTrCP and deregulation of p53-mediated control lead to wild-type beta-catenin nuclear accumulation in lung tumorigenesis. | Oncogene 20080724 |
Synthesis and antiproliferative activities of 5-azacytidine analogues in human leukemia cells. | Molecules (Basel, Switzerland) 20080723 |
Persistent downregulation of the pancarcinoma-associated epithelial cell adhesion molecule via active intranuclear methylation. | International journal of cancer 20080715 |
Assessment of NORE1A as a putative tumor suppressor in human neuroblastoma. | International journal of cancer 20080715 |
A novel effect of DNA methyltransferase and histone deacetylase inhibitors: NFkappaB inhibition in malignant myeloblasts. | Cell cycle (Georgetown, Tex.) 20080715 |
Dissecting direct reprogramming through integrative genomic analysis. | Nature 20080703 |
CHD5, a tumor suppressor gene deleted from 1p36.31 in neuroblastomas. | Journal of the National Cancer Institute 20080702 |
Cytogenetic features in myelodysplastic syndromes. | Annals of hematology 20080701 |
Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine. | International journal of cancer 20080701 |
Acute myeloid leukemia in the elderly: conventional and novel treatment approaches. | Blood reviews 20080701 |
Incubation with somatostatin, 5-aza decitabine and trichostatin up-regulates somatostatin receptor expression in prostate cancer cells. | Oncology reports 20080701 |
Histone H3 (lys-9) deacetylation is associated with transcriptional silencing of E-cadherin in colorectal cancer cell lines. | Cancer investigation 20080701 |
[Promoter methylation regulates KIR3DL1 gene expression in NK-92MI cell line]. | Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20080701 |
Mammalian target of rapamycin pathway inhibition enhances the effects of 5-aza-dC on suppressing cell proliferation in human gastric cancer cell lines. | Science in China. Series C, Life sciences 20080701 |
[Differences between adipose-derived stem cells and mesenchymal stem cells in differentiation into cardiomyocytes]. | Sheng li xue bao : [Acta physiologica Sinica] 20080625 |
Proteins that bind methylated DNA and human cancer: reading the wrong words. | British journal of cancer 20080617 |
Frequently methylated tumor suppressor genes in head and neck squamous cell carcinoma. | Cancer research 20080615 |
ssDNA-binding protein 2 is frequently hypermethylated and suppresses cell growth in human prostate cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080615 |
Down-regulation of hedgehog-interacting protein through genetic and epigenetic alterations in human hepatocellular carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080615 |
Induction of MHC class I-related chain B (MICB) by 5-aza-2'-deoxycytidine. | Biochemical and biophysical research communications 20080613 |
SPARC promoter hypermethylation in colorectal cancers can be reversed by 5-Aza-2'deoxycytidine to increase SPARC expression and improve therapy response. | British journal of cancer 20080603 |
Five azacytidine, a DNA methyltransferase inhibitor, specifically inhibits testicular cord formation and Sertoli cell differentiation in vitro. | Molecular reproduction and development 20080601 |
Epigenetic-based treatments emphasize the biologic differences of core-binding factor acute myeloid leukemias. | Leukemia research 20080601 |
The DNA demethylating agent 5-aza-2'-deoxycytidine activates NY-ESO-1 antigenicity in orthotopic human glioma. | International journal of cancer 20080601 |
Evolution of decitabine development: accomplishments, ongoing investigations, and future strategies. | Cancer 20080601 |
Oct4 is epigenetically regulated by methylation in normal placenta and gestational trophoblastic disease. | Placenta 20080601 |
The effect of azacitidine on interleukin-6 signaling and nuclear factor-kappaB activation and its in vitro and in vivo activity against multiple myeloma. | Haematologica 20080601 |
DNA methylation controls Foxp3 gene expression. | European journal of immunology 20080601 |
Generalized granuloma annulare as an initial manifestation of chronic myelomonocytic leukemia: a report of 2 cases. | The American Journal of dermatopathology 20080601 |
Epigenetic modification is involved in aberrant expression of class III beta-tubulin, TUBB3, in ovarian cancer cells. | International journal of oncology 20080601 |
Carcinoma-associated fibroblast-like differentiation of human mesenchymal stem cells. | Cancer research 20080601 |
The human receptor tyrosine kinase Axl gene--promoter characterization and regulation of constitutive expression by Sp1, Sp3 and CpG methylation. | Bioscience reports 20080601 |
Epigenetic treatment of myelodysplastic syndromes and acute myeloid leukemias. | Current medicinal chemistry 20080601 |
Demethylating agent 5-aza-2'-deoxycytidine enhances susceptibility of bladder transitional cell carcinoma to Cisplatin. | Urology 20080601 |
Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression. | Cancer cell 20080601 |
DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications. | Cancer cell 20080601 |
[DNA methylation regulates kir3dl1 gene expression in K562 cell line]. | Zhongguo shi yan xue ye xue za zhi 20080601 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20080601 |
Pharmaceutical approval update. | P & T : a peer-reviewed journal for formulary management 20080601 |
Investigation of transcriptional gene silencing and mechanism induced by shRNAs targeted to RUNX3 in vitro. | World journal of gastroenterology 20080521 |
Chronic azacitidine treatment results in differentiating effects, sensitizes against bicalutamide in androgen-independent prostate cancer cells. | The Prostate 20080515 |
Effects of cellular differentiation, chromosomal integration and 5-aza-2'-deoxycytidine treatment on human papillomavirus-16 DNA methylation in cultured cell lines. | Virology 20080510 |
Relationship between DNA methylation states and transcription of individual isoforms encoded by the protocadherin-alpha gene cluster. | The Journal of biological chemistry 20080502 |
An epigenetic disorder may cause aberrant expression of aromatase gene in endometriotic stromal cells. | Fertility and sterility 20080501 |
DNA methylation and histone acetylation work in concert to regulate memory formation and synaptic plasticity. | Neurobiology of learning and memory 20080501 |
Potentiation of reactive oxygen species is a marker for synergistic cytotoxicity of MS-275 and 5-azacytidine in leukemic cells. | Leukemia research 20080501 |
DNA hypomethylation circuit of the mouse oocyte-specific histone H1foo gene in female germ cell lineage. | Biology of reproduction 20080501 |
A phase II study of 5-azacitidine for patients with primary and post-essential thrombocythemia/polycythemia vera myelofibrosis. | Leukemia 20080501 |
Epigenetic and HIF-1 regulation of stanniocalcin-2 expression in human cancer cells. | Experimental cell research 20080501 |
Pax3 activation promotes the differentiation of mesenchymal stem cells toward the myogenic lineage. | Experimental cell research 20080501 |
Reduced T-cadherin expression and promoter methylation are associated with the development and progression of hepatocellular carcinoma. | International journal of oncology 20080501 |
ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation. | Autoimmunity 20080501 |
Internuclear gene silencing in Phytophthora infestans is established through chromatin remodelling. | Microbiology (Reading, England) 20080501 |
Decitabine-induced demethylation of 5' CpG island in GADD45A leads to apoptosis in osteosarcoma cells. | Neoplasia (New York, N.Y.) 20080501 |
Reprogramming epigenetic silencing: artificial transcription factors synergize with chromatin remodeling drugs to reactivate the tumor suppressor mammary serine protease inhibitor. | Molecular cancer therapeutics 20080501 |
DNA methylation in T cells from idiopathic lupus and drug-induced lupus patients. | Autoimmunity reviews 20080501 |
TLS-ERG leukemia fusion protein deregulates cyclin-dependent kinase 1 and blocks terminal differentiation of myeloid progenitor cells. | Molecular cancer research : MCR 20080501 |
Promoter hypermethylation of FANCF and outcome in advanced ovarian cancer. | British journal of cancer 20080422 |
Global genomic methylation levels in the liver and gonads of the three-spine stickleback (Gasterosteus aculeatus) after exposure to hexabromocyclododecane and 17-beta oestradiol. | Environment international 20080401 |
Pharmacokinetics of decitabine administered as a 3-h infusion to patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). | Cancer chemotherapy and pharmacology 20080401 |
Mechanisms of DNA breaks induction in vivo by 5-azacytidine: paths of micronucleus induction by azaC. | Journal of applied toxicology : JAT 20080401 |
Efficacy of decitabine in the treatment of patients with chronic myelomonocytic leukemia (CMML). | Leukemia research 20080401 |
V1a vasopressin receptor expression is modulated during myogenic differentiation. | Differentiation; research in biological diversity 20080401 |
5-Aza-2'-deoxycytidine suppresses human renal carcinoma cell growth in a xenograft model via up-regulation of the connexin 32 gene. | British journal of pharmacology 20080401 |
Epigenetic silencing of maspin expression occurs early in the conversion of keratocytes to fibroblasts. | Experimental eye research 20080401 |
Clinical effectiveness of decitabine in severe sickle cell disease. | British journal of haematology 20080401 |
Analysis of protein domains and Rett syndrome mutations indicate that multiple regions influence chromatin-binding dynamics of the chromatin-associated protein MECP2 in vivo. | Journal of cell science 20080401 |
Response to the methylation inhibitor dihydro-5-azacytidine in mesothelioma is not associated with methylation of p16INK4a: results of cancer and leukemia group B 159904. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20080401 |
Methylation silencing of transforming growth factor-beta receptor type II in rat prostate cancers. | Cancer research 20080401 |
DNA methyltransferase inhibitors: class effect or unique agents? | Leukemia & lymphoma 20080401 |
Activity of decitabine in patients with myelodysplastic syndrome previously treated with azacitidine. | Leukemia & lymphoma 20080401 |
Selective POTE paralogs on chromosome 2 are expressed in human embryonic stem cells. | Stem cells and development 20080401 |
The role of DNA hypermethylation and demethylation in cancer and cancer therapy. | Current oncology (Toronto, Ont.) 20080401 |
[Analysis of in vitro anti-leukemia effect of 5-aza-2'-deoxycitydine]. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20080401 |
The novel gene LRP15 is regulated by DNA methylation and confers increased efficiency of DNA repair of ultraviolet-induced DNA damage. | BMB reports 20080331 |
The N-methyl-D-aspartate receptor type 2A is frequently methylated in human colorectal carcinoma and suppresses cell growth. | Oncogene 20080327 |
5-Aza-2'-deoxycytidine increases the expression of anti-angiogenic vascular endothelial growth factor 189b variant in human lung microvascular endothelial cells. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080301 |
DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function. | Human molecular genetics 20080301 |
Promoting effect of 5-azacytidine on the myogenic differentiation of bone marrow stromal cells. | European journal of cell biology 20080301 |
Supportive care, growth factors, and new therapies in myelodysplastic syndromes. | Blood reviews 20080301 |
Promoter-targeted siRNAs induce gene silencing of simian immunodeficiency virus (SIV) infection in vitro. | Molecular therapy : the journal of the American Society of Gene Therapy 20080301 |
Cardiomyogenic potential of human adult bone marrow mesenchymal stem cells in vitro. | The Thoracic and cardiovascular surgeon 20080301 |
Homocysteine-induced extracellular superoxide dismutase and its epigenetic mechanisms in monocytes. | The Journal of experimental biology 20080301 |
Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo. | Neoplasia (New York, N.Y.) 20080301 |
[Pathophysiology, diagnosis and treatment of anemia]. | Nihon rinsho. Japanese journal of clinical medicine 20080301 |
[Myelodysplastic syndrome]. | Nihon rinsho. Japanese journal of clinical medicine 20080301 |
SIRT1 inhibition alleviates gene silencing in Fragile X mental retardation syndrome. | PLoS genetics 20080301 |
The epigenetic origin of aneuploidy. | Current genomics 20080301 |
Expression of BORIS in melanoma: lack of association with MAGE-A1 activation. | International journal of cancer 20080215 |
Alpha anomer of 5-aza-2'-deoxycytidine down-regulates hTERT mRNA expression in human leukemia HL-60 cells. | Biochemical pharmacology 20080215 |
Induction of hypomethylation and molecular response after decitabine therapy in patients with chronic myelomonocytic leukemia. | Blood 20080215 |
Tricyclic HIV integrase inhibitors: potent and orally bioavailable C5-aza analogs. | Bioorganic & medicinal chemistry letters 20080215 |
Simultaneous determination of decitabine and vorinostat (Suberoylanalide hydroxamic acid, SAHA) by liquid chromatography tandem mass spectrometry for clinical studies. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080215 |
DNA methylation and mechanism of action of 5-azacytidine. | Blood 20080215 |
Differential epigenetic regulation of Aiolos expression in human tumoral cell lines and primary cells. | FEBS letters 20080206 |
Three-dimensional epidermis-like growth of human mesenchymal stem cells on dermal equivalents: contribution to tissue organization by adaptation of myofibroblastic phenotype and function. | Differentiation; research in biological diversity 20080201 |
Induction of MHC class I molecule cell surface expression and epigenetic activation of antigen-processing machinery components in a murine model for human papilloma virus 16-associated tumours. | Immunology 20080201 |
An ATM- and Rad3-related (ATR) signaling pathway and a phosphorylation-acetylation cascade are involved in activation of p53/p21Waf1/Cip1 in response to 5-aza-2'-deoxycytidine treatment. | The Journal of biological chemistry 20080201 |
Genome-wide demethylation promotes triplet repeat instability independently of homologous recombination. | DNA repair 20080201 |
DNA demethylation and histone deacetylation inhibition co-operate to re-express estrogen receptor beta and induce apoptosis in prostate cancer cell-lines. | The Prostate 20080201 |
Drugs affecting prelamin A processing: effects on heterochromatin organization. | Experimental cell research 20080201 |
Hypomethylation and apoptosis in 5-azacytidine-treated myeloid cells. | Experimental hematology 20080201 |
[Effect of (-)-epigallocatechin-3-gallate and 5-AZA-CdR on expression of X-linked inhibitor of apoptosis protein-associated factor 1 in human leukemia HL-60 and K562 cells]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080201 |
Solving the mystery of myelodysplasia. | PLoS medicine 20080201 |
Epigenetic down-regulation and suppressive role of DCBLD2 in gastric cancer cell proliferation and invasion. | Molecular cancer research : MCR 20080201 |
DNMT1 as a molecular target in a multimodality-resistant phenotype in tumor cells. | Molecular cancer research : MCR 20080201 |
[Methylation of PTPRG gene and its regulation in gastric cancer]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20080201 |
Identification of DNA hypermethylation of SOX9 in association with bladder cancer progression using CpG microarrays. | British journal of cancer 20080129 |
Functional epigenomics approach to identify methylated candidate tumour suppressor genes in renal cell carcinoma. | British journal of cancer 20080129 |
Clinical significance of the reduced expression of G protein gamma 7 (GNG7) in oesophageal cancer. | British journal of cancer 20080129 |
Regulation of demethylation and re-expression of RASSF1A gene in gastric cancer cell lines by combined treatment of 5-Aza-CdR and NaB. | World journal of gastroenterology 20080128 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. | Journal of medicinal chemistry 20080124 |
Reversal of methylation silencing of Apo2L/TRAIL receptor 1 (DR4) expression overcomes resistance of SK-MEL-3 and SK-MEL-28 melanoma cells to interferons (IFNs) or Apo2L/TRAIL. | Oncogene 20080117 |
Epigenetic regulation of microRNA-370 by interleukin-6 in malignant human cholangiocytes. | Oncogene 20080110 |
Epigenetic silencing of telomerase and a non-alkylating agent as a novel therapeutic approach for glioma. | Brain research 20080110 |
Activity-dependent suppression of miniature neurotransmission through the regulation of DNA methylation. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080109 |
PU.1 is dispensable to block erythroid differentiation in Friend erythroleukemia cells. | Leukemia research 20080101 |
PI-PLCbeta-1 and activated Akt levels are linked to azacitidine responsiveness in high-risk myelodysplastic syndromes. | Leukemia 20080101 |
Neither DNA hypomethylation nor changes in the kinetics of erythroid differentiation explain 5-azacytidine's ability to induce human fetal hemoglobin. | Blood 20080101 |
Epigenetic inactivation of microRNA gene hsa-mir-9-1 in human breast cancer. | The Journal of pathology 20080101 |
Promoter methylation is associated with the age-dependent loss of N-cadherin in the rat kidney. | American journal of physiology. Renal physiology 20080101 |
DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B. | Molecular and cellular biology 20080101 |
Hypermethylation of the somatostatin promoter is a common, early event in human esophageal carcinogenesis. | Cancer 20080101 |
CpG methylation plays a vital role in determining tissue- and cell-specific expression of the human cell-death-inducing DFF45-like effector A gene through the regulation of Sp1/Sp3 binding. | Nucleic acids research 20080101 |
Epigenetic memory of an active gene state depends on histone H3.3 incorporation into chromatin in the absence of transcription. | Nature cell biology 20080101 |
Human chromosome fragility. | Biochimica et biophysica acta 20080101 |
Hypomethylation of interleukin-4 and -6 promoters in T cells from systemic lupus erythematosus patients. | Acta pharmacologica Sinica 20080101 |
Genome-wide transcriptional response to 5-aza-2'-deoxycytidine and trichostatin a in multiple myeloma cells. | Cancer research 20080101 |
Tandem repeat mutation, global DNA methylation, and regulation of DNA methyltransferases in cultured mouse embryonic fibroblast cells chronically exposed to chemicals with different modes of action. | Environmental and molecular mutagenesis 20080101 |
Myelodysplastic syndromes: introduction. | Seminars in hematology 20080101 |
DNA methyltransferase and histone deacetylase inhibitors in the treatment of myelodysplastic syndromes. | Seminars in hematology 20080101 |
Targeted therapies in myelodysplastic syndrome. | Seminars in hematology 20080101 |
DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines. | Molecular cancer 20080101 |
Reactivation of inactive X chromosome: a potential culprit and therapeutic target for systemic lupus erythematosus. | Medical hypotheses 20080101 |
Reproducible, ultra high-throughput formation of multicellular organization from single cell suspension-derived human embryonic stem cell aggregates. | PloS one 20080101 |
Pharmacogenomics and therapeutics of hemoglobinopathies. | Hemoglobin 20080101 |
Inositide signaling: Nuclear targets and involvement in myelodysplastic syndromes. | Advances in enzyme regulation 20080101 |
FOXP3 promoter demethylation reveals the committed Treg population in humans. | PloS one 20080101 |
Common variants within MECP2 confer risk of systemic lupus erythematosus. | PloS one 20080101 |
Cell type-specific activation of the cytomegalovirus promoter by dimethylsulfoxide and 5-aza-2'-deoxycytidine. | The international journal of biochemistry & cell biology 20080101 |
DNA demethylation-dependent enhancement of toll-like receptor-2 gene expression in cystic fibrosis epithelial cells involves SP1-activated transcription. | BMC molecular biology 20080101 |
HIV-1 latency in actively dividing human T cell lines. | Retrovirology 20080101 |
Importance of dose-schedule of 5-aza-2'-deoxycytidine for epigenetic therapy of cancer. | BMC cancer 20080101 |
Genomic imprinting of IGF2 in marsupials is methylation dependent. | BMC genomics 20080101 |
Estrogen receptor and HER2/neu status affect epigenetic differences of tumor-related genes in primary breast tumors. | Breast cancer research : BCR 20080101 |
Comparative study of mesenchymal stem cells from C57BL/10 and mdx mice. | BMC cell biology 20080101 |
Epigenetic changes within the promoter region of the HLA-G gene in ovarian tumors. | Molecular cancer 20080101 |
Epigenetic modification of histone 3 at lysine 9 in sheep zygotes and its relationship with DNA methylation. | BMC developmental biology 20080101 |
Anticancer drug discovery targeting DNA hypermethylation. | Current medicinal chemistry 20080101 |
Involvement of TSC genes and differential expression of other members of the mTOR signaling pathway in oral squamous cell carcinoma. | BMC cancer 20080101 |
Isolation and characterization of side population stem cells in articular synovial tissue. | BMC musculoskeletal disorders 20080101 |
Hypermethylation-modulated downregulation of claudin-7 expression promotes the progression of colorectal carcinoma. | Pathobiology : journal of immunopathology, molecular and cellular biology 20080101 |
HDAC inhibitors act with 5-aza-2'-deoxycytidine to inhibit cell proliferation by suppressing removal of incorporated abases in lung cancer cells. | PloS one 20080101 |
A cytosine methyltransferase homologue is essential for sexual development in Aspergillus nidulans. | PloS one 20080101 |
Journal of hematology & oncology: a journal open to all. | Journal of hematology & oncology 20080101 |
Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways. | Journal of hematology & oncology 20080101 |
Age-specific epigenetic drift in late-onset Alzheimer's disease. | PloS one 20080101 |
[Growth and differentiation of cell hybrids obtained by fusing mouse PCC4azal teratocarcinoma cells and mouse spleen cells under different in vitro culture conditions]. | Ontogenez 20080101 |
Topology of evolving, mutagenized viral populations: quasispecies expansion, compression, and operation of negative selection. | BMC evolutionary biology 20080101 |
Prevention of murine experimental corneal trauma by epigenetic events regulating claudin 6 and claudin 9. | Japanese journal of ophthalmology 20080101 |
Epigenetic mechanisms involved in differential MDR1 mRNA expression between gastric and colon cancer cell lines and rationales for clinical chemotherapy. | BMC gastroenterology 20080101 |
A patient with glycogen storage disease type Ib presenting with acute myeloid leukemia (AML) bearing monosomy 7 and translocation t(3;8)(q26;q24) after 14 years of treatment with granulocyte colony-stimulating factor (G-CSF): a case report. | Journal of medical case reports 20080101 |
DNA methylation: its role in cancer development and therapy. | Current problems in cancer 20080101 |
Synergistic effect of 5-Aza-2'-deoxycytidine and genistein in combination against leukemia. | Oncology research 20080101 |
Methylation of WTH3, a possible drug resistant gene, inhibits p53 regulated expression. | BMC cancer 20080101 |
The fungus Neurospora crassa displays telomeric silencing mediated by multiple sirtuins and by methylation of histone H3 lysine 9. | Epigenetics & chromatin 20080101 |
Sensitive detection of colorectal cancer in peripheral blood by septin 9 DNA methylation assay. | PloS one 20080101 |
Ovarian cancer plasticity and epigenomics in the acquisition of a stem-like phenotype. | Journal of ovarian research 20080101 |
Mechanisms of metastasis. | Breast cancer research : BCR 20080101 |
Aberrant allele-specific replication, independent of parental origin, in blood cells of cancer patients. | BMC cancer 20080101 |
Epigenetic deregulation through DNA demethylation seems not to interfere with the differentiation of epithelia from pre-gastrulating rat embryos in vitro. | Acta dermatovenerologica Croatica : ADC 20080101 |
[The role of DNA methylation and histone modifications in structural maintainance of heterochromatin domains (chromocenters)]. | Tsitologiia 20080101 |
In vitro cardiogenesis can be initiated in human CD34+ cells. | Indian heart journal 20080101 |
[Osteogenesis of human vascular endothelial cells in culture]. | Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20080101 |
Epigenetics, behaviour, and health. | Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20080101 |
The effects of continued azacitidine treatment cycles on response in higher risk patients with myelodysplastic syndromes: an update. | Ecancermedicalscience 20080101 |
Azacitidine prolongs overall survival and reduces infections and hospitalizations in patients with WHO-defined acute myeloid leukaemia compared with conventional care regimens: an update. | Ecancermedicalscience 20080101 |
[Epigenetic regulation of expression of retinoic acid receptor beta gene in leukemia cell]. | Zhonghua yi xue za zhi 20071225 |
Re-expression of methylation-induced tumor suppressor gene silencing is associated with the state of histone modification in gastric cancer cell lines. | World journal of gastroenterology 20071214 |
PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation. | Oncogene 20071213 |
Epigenetic regulation of leptin affects MMP-13 expression in osteoarthritic chondrocytes: possible molecular target for osteoarthritis therapeutic intervention. | Annals of the rheumatic diseases 20071201 |
Hepatic differentiation of human bone marrow-derived UE7T-13 cells: Effects of cytokines and CCN family gene expression. | Hepatology research : the official journal of the Japan Society of Hepatology 20071201 |
Epigenetic dysregulation of Wnt signaling pathway in multiple myeloma. | Leukemia 20071201 |
Downregulation of microRNAs-143 and -145 in B-cell malignancies. | Cancer science 20071201 |
Downregulation of several fibulin genes in prostate cancer. | The Prostate 20071201 |
Inducible expression of a prostate cancer-testis antigen, SSX-2, following treatment with a DNA methylation inhibitor. | The Prostate 20071201 |
DNA hypomethylation is crucial for apoptotic DNA to induce systemic lupus erythematosus-like autoimmune disease in SLE-non-susceptible mice. | Rheumatology (Oxford, England) 20071201 |
Azacitidine-associated hyperthermia and interstitial pneumonitis in a patient with myelodysplastic syndrome. | Pharmacotherapy 20071201 |
The role of azacitidine in the treatment of myelodysplastic syndromes. | Expert opinion on investigational drugs 20071201 |
Promoter hypermethylation of the RUNX3 gene in esophageal squamous cell carcinoma. | Cancer investigation 20071201 |
[5-azacytidine enhances anti-tumor efficacy of doxorubicin to neuroblastoma cell lines]. | Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20071201 |
[MicroRNAs can be expressed in cardiomyocyte-like cells differentiated from human mesenchymal stem cells]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20071201 |
Phase II study of azacitidine to restore responsiveness of prostate cancer to hormonal therapy. | Clinical genitourinary cancer 20071201 |
[In vitro differentiation of rat mesenchymal stem cells into skeletal muscle cells induced by myoblast differentiation factor and 5-azacytidine]. | Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20071201 |
Epigenetic lesions in malignant melanoma. | Current pharmaceutical biotechnology 20071201 |
Targeted therapies in the management of metastatic bladder cancer. | Biologics : targets & therapy 20071201 |
Study of the degradation of 5-azacytidine as a model of unstable drugs using a stopped-flow method and further data analysis with multivariate curve resolution. | Talanta 20071130 |
Metastatic suppressor genes inactivated by aberrant methylation in gastric cancer. | World journal of gastroenterology 20071121 |
Genetic and epigenetic changes in the common 1p36 deletion in neuroblastoma tumours. | British journal of cancer 20071119 |
Homocysteine inhibits endothelial cell growth via DNA hypomethylation of the cyclin A gene. | Blood 20071115 |
The similar effect of transplantation of marrow-derived mesenchymal stem cells with or without prior differentiation induction in experimental myocardial infarction. | Journal of biomedical science 20071101 |
Oral decitabine reactivates expression of the methylated gamma-globin gene in Papio anubis. | American journal of hematology 20071101 |
Demethylation of CD40LG on the inactive X in T cells from women with lupus. | Journal of immunology (Baltimore, Md. : 1950) 20071101 |
Multidimensional liquid phase protein separations in conjunction with stable isotope labelling for quantitative proteomics. | Proteomics 20071101 |
Determining the global DNA methylation status of rat according to the identifier repetitive elements. | Electrophoresis 20071101 |
p300 expression repression by hypermethylation associated with tumour invasion and metastasis in oesophageal squamous cell carcinoma. | Journal of clinical pathology 20071101 |
Increased iodine uptake in thyroid carcinoma after treatment with sodium butyrate and decitabine (5-Aza-dC). | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20071101 |
The Cables gene on chromosome 18q is silenced by promoter hypermethylation and allelic loss in human colorectal cancer. | The American journal of pathology 20071101 |
Regulation of the CLDN3 gene in ovarian cancer cells. | Cancer biology & therapy 20071101 |
[Aberrant methylation of tumor suppressor genes in renal cell carcinoma]. | Ai zheng = Aizheng = Chinese journal of cancer 20071101 |
Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors. | Neoplasia (New York, N.Y.) 20071101 |
Treatment options in advanced myelodysplastic syndrome, with emphasis on epigenetic therapy. | International journal of hematology 20071101 |
Evaluating new treatment options for MDS. | Clinical advances in hematology & oncology : H&O 20071101 |
Induction of flowering by 5-azacytidine in some plant species: relationship between the stability of photoperiodically induced flowering and flower-inducing effect of DNA demethylation. | Physiologia plantarum 20071101 |
[Hypermethylation and regulation of expression of secreted frizzled-related protein genes in colorectal tumor]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20071101 |
ZIC1 gene expression is controlled by DNA and histone methylation in mesenchymal proliferations. | FEBS letters 20071030 |
Promoter-independent regulation of vimentin expression in mammary epithelial cells by val(12)ras and TGFbeta. | Experimental cell research 20071015 |
Nucleotide excision repair and homologous recombination systems commit differentially to the repair of DNA-protein crosslinks. | Molecular cell 20071012 |
Combining epigenetic and cytotoxic therapy in the treatment of solid tumors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071010 |
Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071010 |
Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancer. | British journal of cancer 20071008 |
Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells. | Oncogene 20071004 |
Downregulation of connexin 43 in nasopharyngeal carcinoma cells is related to promoter methylation. | Oral oncology 20071001 |
Interconversion of intra- and extra-chromosomal sites of gene amplification by modulation of gene expression and DNA methylation. | Journal of cellular biochemistry 20071001 |
Differentiation-promoting drugs up-regulate NKG2D ligand expression and enhance the susceptibility of acute myeloid leukemia cells to natural killer cell-mediated lysis. | Leukemia research 20071001 |
Chromatin changes on the GSTP1 promoter associated with its inactivation in prostate cancer. | Molecular carcinogenesis 20071001 |
Epigenetic inactivation of the metastasis suppressor RECK enhances invasion of human colon cancer cells. | Journal of cellular physiology 20071001 |
Novel approach for detecting global epigenetic alterations associated with tumor cell aneuploidy. | International journal of cancer 20071001 |
Potential advantages of DNA methyltransferase 1 (DNMT1)-targeted inhibition for cancer therapy. | Journal of molecular medicine (Berlin, Germany) 20071001 |
Safety and clinical activity of the combination of 5-azacytidine, valproic acid, and all-trans retinoic acid in acute myeloid leukemia and myelodysplastic syndrome. | Blood 20071001 |
Promoter methylation regulates estrogen receptor 2 in human endometrium and endometriosis. | Biology of reproduction 20071001 |
In vitro cardiomyogenic differentiation of adult human bone marrow mesenchymal stem cells. The role of 5-azacytidine. | Interactive cardiovascular and thoracic surgery 20071001 |
Chromium cross-links histone deacetylase 1-DNA methyltransferase 1 complexes to chromatin, inhibiting histone-remodeling marks critical for transcriptional activation. | Molecular and cellular biology 20071001 |
Epigenetic inactivation of the CHFR gene in cervical cancer contributes to sensitivity to taxanes. | International journal of oncology 20071001 |
Methylation and intratumoural heterogeneity of 14-3-3 sigma in oral cancer. | Oncology reports 20071001 |
Epigenetic alterations and cancer: new targets for therapy. | IDrugs : the investigational drugs journal 20071001 |
O6-methylguanine-DNA-methyltransferase promoter demethylation is involved in basic fibroblast growth factor induced resistance against temozolomide in human melanoma cells. | Molecular cancer therapeutics 20071001 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20071001 |
Effects of 5-Aza-CdR on cell proliferation of breast cancer cell line MDA-MB-435S and expression of maspin gene. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20071001 |
Decitabine in the treatment of myelodysplastic syndromes. | Therapeutics and clinical risk management 20071001 |
Frequent methylation-associated silencing of a candidate tumor-suppressor, CRABP1, in esophageal squamous-cell carcinoma. | Oncogene 20070927 |
Hypermethylation of the nel-like 1 gene is a common and early event and is associated with poor prognosis in early-stage esophageal adenocarcinoma. | Oncogene 20070920 |
Gene induction and apoptosis in human hepatocellular carci-noma cells SMMC-7721 exposed to 5-aza-2'-deoxycytidine. | Chinese medical journal 20070920 |
Regulation and expression of human CYP7B1 in prostate: overexpression of CYP7B1 during progression of prostatic adenocarcinoma. | The Prostate 20070915 |
v-Src-mediated down-regulation of SSeCKS metastasis suppressor gene promoter by the recruitment of HDAC1 into a USF1-Sp1-Sp3 complex. | The Journal of biological chemistry 20070914 |
Match unrelated bone marrow transplantation in a case of high risk myelodysplastic syndrome treated with azacitidine and concomitant 1alpha-25-dihydroxyvitamin D3, as differentiating agent. | Leukemia research 20070901 |
Clonogenic acute myelogenous leukemia cells are heterogeneous with regard to regulation of differentiation and effect of epigenetic pharmacological targeting. | Leukemia research 20070901 |
Analysis of the limitations of hepatitis B surface antigen expression in soybean cell suspension cultures. | Plant cell reports 20070901 |
Adverse effects of 5-aza-2'-deoxycytidine on spermatogenesis include reduced sperm function and selective inhibition of de novo DNA methylation. | The Journal of pharmacology and experimental therapeutics 20070901 |
CDKN2B methylation status and isolated chromosome 7 abnormalities predict responses to treatment with 5-azacytidine. | Leukemia 20070901 |
Dynamic DNA methylation reprogramming: active demethylation and immediate remethylation in the male pronucleus of bovine zygotes. | Developmental dynamics : an official publication of the American Association of Anatomists 20070901 |
Phase I study of decitabine alone or in combination with valproic acid in acute myeloid leukemia. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070901 |
Hydroxycarbamide in combination with azacitidine or decitabine is antagonistic on DNA methylation inhibition. | British journal of haematology 20070901 |
Decitabine up-regulates S100A2 expression and synergizes with IFN-gamma to kill uveal melanoma cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070901 |
The use of hypomethylating agents in the treatment of hematologic malignancies. | Leukemia & lymphoma 20070901 |
5-Azacytidine induced methyltransferase-DNA adducts block DNA replication in vivo. | Cancer research 20070901 |
Transbuccal delivery of 5-aza-2 -deoxycytidine: effects of drug concentration, buffer solution, and bile salts on permeation. | AAPS PharmSciTech 20070901 |
The histone deacetylase inhibitor trichostatin A downregulates human MDR1 (ABCB1) gene expression by a transcription-dependent mechanism in a drug-resistant small cell lung carcinoma cell line model. | British journal of cancer 20070820 |
SGNE1/7B2 is epigenetically altered and transcriptionally downregulated in human medulloblastomas. | Oncogene 20070816 |
Characterization of acid-base properties of unstable drugs using a continuous-flow system with UV-vis spectrophotometric detection. | Journal of pharmaceutical and biomedical analysis 20070815 |
Epigenetic modulation of estrogen receptor-alpha by pRb family proteins: a novel mechanism in breast cancer. | Cancer research 20070815 |
Ornithine decarboxylase antizyme upregulates DNA-dependent protein kinase and enhances the nonhomologous end-joining repair of DNA double-strand breaks in human oral cancer cells. | Biochemistry 20070807 |
Frequent inactivation of SPARC by promoter hypermethylation in colon cancers. | International journal of cancer 20070801 |
Epigenetic silencing of the candidate tumor suppressor gene PROX1 in sporadic breast cancer. | International journal of cancer 20070801 |
Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (Vorinostat, SAHA) profoundly inhibits the growth of human pancreatic cancer cells. | International journal of cancer 20070801 |
Trichostatin A, sodium butyrate, and 5-aza-2'-deoxycytidine alter the expression of glucocorticoid receptor alpha and beta isoforms in Hut-78 T- and Raji B-lymphoma cell lines. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20070801 |
Transcriptional activation of steroidogenic factor-1 by hypomethylation of the 5' CpG island in endometriosis. | The Journal of clinical endocrinology and metabolism 20070801 |
Preferential cytogenetic response to continuous intravenous low-dose decitabine (DAC) administration in myelodysplastic syndrome with monosomy 7. | Blood 20070801 |
Decitabine dosage in myelodysplastic syndromes. | Blood 20070801 |
Frequent inactivation of RAMP2, EFEMP1 and Dutt1 in lung cancer by promoter hypermethylation. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070801 |
The interferon-alpha responsive gene TMEM7 suppresses cell proliferation and is downregulated in human hepatocellular carcinoma. | Cancer genetics and cytogenetics 20070801 |
Decitabine and its role in the treatment of hematopoietic malignancies. | Leukemia & lymphoma 20070801 |
Monocytic skin nodules in chronic myelomonocytic leukemia: clinical response to decitabine therapy. | Leukemia & lymphoma 20070801 |
High expressions of neuronatin isoforms in favorable neuroblastoma. | Journal of pediatric hematology/oncology 20070801 |
Lenalidomide: a brief review of its therapeutic potential in myelodysplastic syndromes. | Therapeutics and clinical risk management 20070801 |
Short hairpin RNA causes the methylation of transforming growth factor-beta receptor II promoter and silencing of the target gene in rat hepatic stellate cells. | Biochemical and biophysical research communications 20070727 |
Epigenetic silencing of HSulf-1 in ovarian cancer:implications in chemoresistance. | Oncogene 20070726 |
[The role of secreted Wnt-antagonist genes hypermethylation in early detection of colorectal tumor]. | Zhonghua yi xue za zhi 20070724 |
Xeroderma pigmentosum group C gene expression is predominantly regulated by promoter hypermethylation and contributes to p53 mutation in lung cancers. | Oncogene 20070719 |
Potential target antigens for immunotherapy in human pancreatic cancer. | Cancer letters 20070718 |
Epigenetic deregulation of multiple S100 gene family members by differential hypomethylation and hypermethylation events in medulloblastoma. | British journal of cancer 20070716 |
Silencing of tissue factor pathway inhibitor-2 gene in malignant melanomas. | International journal of cancer 20070715 |
Effect of cytarabine and decitabine in combination in human leukemic cell lines. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070715 |
Hypermethylation of Ron proximal promoter associates with lack of full-length Ron and transcription of oncogenic short-Ron from an internal promoter. | Oncogene 20070705 |
Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer. | Breast cancer research and treatment 20070701 |
Epigenetic regulation of human alpha1d-adrenergic receptor gene expression: a role for DNA methylation in Sp1-dependent regulation. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070701 |
The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas. | Laboratory investigation; a journal of technical methods and pathology 20070701 |
Lysyl oxidase-like 2 expression is increased in colon and esophageal tumors and associated with less differentiated colon tumors. | Genes, chromosomes & cancer 20070701 |
Evidence of endogenous mu opioid receptor regulation by epigenetic control of the promoters. | Molecular and cellular biology 20070701 |
Endosperm-specific hypomethylation, and meiotic inheritance and variation of DNA methylation level and pattern in sorghum (Sorghum bicolor L.) inter-strain hybrids. | TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik 20070701 |
Promoter methylation as a common mechanism for inactivating E-cadherin in human salivary gland adenoid cystic carcinoma. | Cancer 20070701 |
Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides. | Cancer research 20070701 |
Effects of chromatin-modifying agents on CD34+ cells from patients with idiopathic myelofibrosis. | Cancer research 20070701 |
Epigenetic inactivation of E-cadherin by promoter hypermethylation in oral carcinoma cells. | Odontology 20070701 |
Use of hypomethylating agents in myelodysplastic syndromes. | Clinical advances in hematology & oncology : H&O 20070701 |
Effects of 5-aza-2'-deoxycytidine on the gene expression profile during embryogenesis of the Ascidian ciona intestinalis: a microarray analysis. | Zoological science 20070701 |
[Relationship between RAR-beta gene expression defect and its methylation]. | Zhonghua fu chan ke za zhi 20070701 |
Expression of GAGE family proteins in malignant melanoma. | Cancer letters 20070628 |
Differential expression of galectins in normal, benign and malignant prostate epithelial cells: silencing of galectin-3 expression in prostate cancer by its promoter methylation. | Biochemical and biophysical research communications 20070622 |
Downregulation and CpG island hypermethylation of NES1/hK10 gene in the pathogenesis of human gastric cancer. | Cancer letters 20070618 |
DNA demethylation reactivation of imprinted genes in cell lines from patients with Prader-Willi syndrome and a mouse model. | American journal of medical genetics. Part A 20070615 |
Epigenetic and functional analysis of IGFBP3 and IGFBPrP1 in cellular immortalization. | Biochemical and biophysical research communications 20070608 |
Comprehensive conformational analysis of the nucleoside analogue 2'-beta-deoxy-6-azacytidine by DFT and MP2 calculations. | The journal of physical chemistry. B 20070607 |
A selective activity of DNMTi decitabine on AML1ETO positive cells? | Leukemia research 20070601 |
Control of hematopoiesis and apoptosis in MDS: more than FLIPing the coin. | Leukemia research 20070601 |
DNA methylation regulates tissue-specific expression of Shank3. | Journal of neurochemistry 20070601 |
Overlapping roles of the methylated DNA-binding protein MBD1 and polycomb group proteins in transcriptional repression of HOXA genes and heterochromatin foci formation. | The Journal of biological chemistry 20070601 |
Transcriptional silencing of the TMS1/ASC tumour suppressor gene by an epigenetic mechanism in hepatocellular carcinoma cells. | The Journal of pathology 20070601 |
Functional up-regulation of human leukocyte antigen class I antigens expression by 5-aza-2'-deoxycytidine in cutaneous melanoma: immunotherapeutic implications. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070601 |
Down-regulation of PU.1 by methylation of distal regulatory elements and the promoter is required for myeloma cell growth. | Cancer research 20070601 |
Epigenetic dysregulation of the death-associated protein kinase/p14/HDM2/p53/Apaf-1 apoptosis pathway in multiple myeloma. | Journal of clinical pathology 20070601 |
[Effect of adenomatous polyposis coli(APC) promoter methylation on gene transcription in lung cancer cell lines]. | Ai zheng = Aizheng = Chinese journal of cancer 20070601 |
Selection for robustness in mutagenized RNA viruses. | PLoS genetics 20070601 |
5-Azacytidine, a DNA methyltransferase inhibitor, induces ATR-mediated DNA double-strand break responses, apoptosis, and synergistic cytotoxicity with doxorubicin and bortezomib against multiple myeloma cells. | Molecular cancer therapeutics 20070601 |
Suppression of DPYD expression in RKO cells via DNA methylation in the regulatory region of the DPYD promoter: a potentially important epigenetic mechanism regulating DPYD expression. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20070601 |
DNA methyltransferases as targets for cancer therapy. | Drugs of today (Barcelona, Spain : 1998) 20070601 |
Re-expression of RASSF1A by 5-Aza-CdR induced demethylation of the promoter region in human biliary tract carcinoma cells. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20070601 |
The comparative effects of gene modulators on thyroid-specific genes and radioiodine uptake. | Cancer biotherapy & radiopharmaceuticals 20070601 |
In silico mining identifies IGFBP3 as a novel target of methylation in prostate cancer. | British journal of cancer 20070521 |
Trichostatin A and 5-aza-2'-deoxycytidine switch S1P from an inhibitor to a stimulator of motility through epigenetic regulation of S1P receptors. | Cancer letters 20070518 |
Heterochromatic gene repression of the retinoic acid pathway in acute myeloid leukemia. | Blood 20070515 |
Genetic redundancy in human cervical carcinoma cells: identification of cells with 'normal' properties. | International journal of cancer 20070515 |
MAGE-A9 mRNA and protein expression in bladder cancer. | International journal of cancer 20070515 |
Epigenetic combination therapy as a tumor-selective treatment approach for hepatocellular carcinoma. | Cancer 20070515 |
Tumor suppressor activity of CCAAT/enhancer binding protein alpha is epigenetically down-regulated in head and neck squamous cell carcinoma. | Cancer research 20070515 |
Acute myeloid leukemia and myelodysplastic syndromes in older patients. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070510 |
Larger numbers of silenced genes in cancer cell lines with increased de novo methylation of scattered CpG sites. | Cancer letters 20070508 |
Effect of combined therapy with low-dose 5-aza-2'-deoxycytidine and irinotecan on colon cancer cell line HCT-15. | Annals of surgical oncology 20070501 |
The C/EBPdelta tumor suppressor is silenced by hypermethylation in acute myeloid leukemia. | Blood 20070501 |
Mechanism of in vivo sister-chromatid exchange induction by 5-azacytidine. | Mutagenesis 20070501 |
The Escherichia coli protein YjjG is a house-cleaning nucleotidase in vivo. | FEMS microbiology letters 20070501 |
Discovery of epigenetically silenced genes in acute myeloid leukemias. | Leukemia 20070501 |
Methylation patterns of IGFBP7 in colon cancer cell lines are associated with levels of gene expression. | The Journal of pathology 20070501 |
Aberrant DNA methylation of the Src kinase Hck, but not of Lyn, in Philadelphia chromosome negative acute lymphocytic leukemia. | Leukemia 20070501 |
The incidence and impact of thrombocytopenia in myelodysplastic syndromes. | Cancer 20070501 |
Complete response of deep neutrophilic dermatosis associated with myelodysplastic syndrome to 5-azacytidine. | The British journal of dermatology 20070501 |
Down-regulation of IL-7Ralpha expression in human T cells via DNA methylation. | Journal of immunology (Baltimore, Md. : 1950) 20070501 |
Methylation of Ras association domain family protein 1, isoform A correlated with proliferation and drug resistance in hepatocellular carcinoma cell line SMMC-7721. | Journal of gastroenterology and hepatology 20070501 |
LOXL1 and LOXL4 are epigenetically silenced and can inhibit ras/extracellular signal-regulated kinase signaling pathway in human bladder cancer. | Cancer research 20070501 |
Tissue factor pathway inhibitor-2 as a frequently silenced tumor suppressor gene in hepatocellular carcinoma. | Hepatology (Baltimore, Md.) 20070501 |
Identification of epigenetically silenced genes in tumor endothelial cells. | Cancer research 20070501 |
Azacitidine pharmacokinetics in an adolescent patient with renal compromise. | Journal of pediatric hematology/oncology 20070501 |
Differential promoter methylation may be a key molecular mechanism in regulating BubR1 expression in cancer cells. | Experimental & molecular medicine 20070430 |
Predicting gene promoter methylation in non-small-cell lung cancer by evaluating sputum and serum. | British journal of cancer 20070423 |
Pharmacologic inhibition of epigenetic modifications, coupled with gene expression profiling, reveals novel targets of aberrant DNA methylation and histone deacetylation in lung cancer. | Oncogene 20070419 |
Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia. | Blood 20070415 |
Chromatin-modifying agents permit human hematopoietic stem cells to undergo multiple cell divisions while retaining their repopulating potential. | Blood 20070415 |
The use of histone deacetylase inhibitor FK228 and DNA hypomethylation agent 5-azacytidine in human bladder cancer therapy. | International journal of cancer 20070415 |
High-resolution analysis of 3p deletion in neuroblastoma and differential methylation of the SEMA3B tumor suppressor gene. | Cancer genetics and cytogenetics 20070415 |
Strategies for achieving transfusion independence in myelodysplastic syndromes. | European journal of oncology nursing : the official journal of European Oncology Nursing Society 20070401 |
Reversal of p15/INK4b hypermethylation in AML1/ETO-positive and -negative myeloid leukemia cell lines. | Leukemia research 20070401 |
Vitamin A and beta-carotene inhibitory effect during 1,2-dimethylhydrazine induced hepatocarcinogenesis potentiated by 5-azacytidine. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070401 |
Methylation and gene silencing of the Ras-related GTPase gene in lung and breast cancers. | Annals of surgical oncology 20070401 |
Differentiation-specific association of HP1alpha and HP1beta with chromocentres is correlated with clustering of TIF1beta at these sites. | Histochemistry and cell biology 20070401 |
Real-time fluorescence tracking of dynamic transgene variegation in stem cells. | Molecular therapy : the journal of the American Society of Gene Therapy 20070401 |
Epigenetic inactivation of chalcone synthase-A transgene transcription in petunia leads to a reversion of the post-transcriptional gene silencing phenotype. | Plant & cell physiology 20070401 |
Transcriptional reactivation of murine cytomegalovirus ie gene expression by 5-aza-2'-deoxycytidine and trichostatin A in latently infected cells despite lack of methylation of the major immediate-early promoter. | The Journal of general virology 20070401 |
Recent advances in myelodysplastic syndromes. | Experimental hematology 20070401 |
5-aza-2'-deoxycytidine delays androgen-independent disease and improves survival in the transgenic adenocarcinoma of the mouse prostate mouse model of prostate cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070401 |
Claudin-7 is highly expressed in chromophobe renal cell carcinoma and renal oncocytoma. | Journal of Korean medical science 20070401 |
[Pluripotential differentiation of QY1 bone marrow mesenchymal stem cell line]. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20070401 |
Promoter methylation of PARG1, a novel candidate tumor suppressor gene in mantle-cell lymphomas. | Haematologica 20070401 |
The comparative effects of gene modulators on thyroid-specific genes and radioiodine uptake. | Cancer biotherapy & radiopharmaceuticals 20070401 |
Current treatment options: impact of cytogenetics on the course of myelodysplasia. | Current treatment options in oncology 20070401 |
Epigenetic silencing of CYP24 in tumor-derived endothelial cells contributes to selective growth inhibition by calcitriol. | The Journal of biological chemistry 20070323 |
Survival advantage with decitabine versus intensive chemotherapy in patients with higher risk myelodysplastic syndrome: comparison with historical experience. | Cancer 20070315 |
Covalent modification of DNA regulates memory formation. | Neuron 20070315 |
DNA methylation as a therapeutic target in cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070315 |
5-AZA-2'-deoxycytidine in cancer immunotherapy: a mouse to man story. | Cancer research 20070315 |
Lytic induction and apoptosis of Epstein-Barr virus-associated gastric cancer cell line with epigenetic modifiers and ganciclovir. | Cancer letters 20070308 |
Improved outcome in childhood acute myeloid leukemia in Singapore with the MRC AML 10 protocol. | Pediatric blood & cancer 20070301 |
Induction of complete remission in a patient with acute myeloid leukemia refractory to high-dose chemotherapy through treatment with 5-azacytidine. | Leukemia research 20070301 |
DNA methyltransferase inhibitors coordinately induce expression of the human reelin and glutamic acid decarboxylase 67 genes. | Molecular pharmacology 20070301 |
Protein synthesis inhibitors, in synergy with 5-azacytidine, restore sodium/iodide symporter gene expression in human thyroid adenoma cell line, KAK-1, suggesting trans-active transcriptional repressor. | The Journal of clinical endocrinology and metabolism 20070301 |
Insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1) has potential tumour-suppressive activity in human lung cancer. | The Journal of pathology 20070301 |
Phase II study of low-dose decitabine in combination with imatinib mesylate in patients with accelerated or myeloid blastic phase of chronic myelogenous leukemia. | Cancer 20070301 |
Characterization of in vitro and in vivo hypomethylating effects of decitabine in acute myeloid leukemia by a rapid, specific and sensitive LC-MS/MS method. | Nucleic acids research 20070301 |
Promoter methylation status of the Cyclin D2 gene is associated with poor prognosis in human epithelial ovarian cancer. | Cancer science 20070301 |
The myelodysplastic syndromes. | Expert opinion on biological therapy 20070301 |
Myelodysplasia: the good, the fair and the ugly. | Best practice & research. Clinical haematology 20070301 |
Epigenetic regulation of Nanog gene in embryonic stem and trophoblast stem cells. | Genes to cells : devoted to molecular & cellular mechanisms 20070301 |
Stress chaperones, mortalin, and pex19p mediate 5-aza-2' deoxycytidine-induced senescence of cancer cells by DNA methylation-independent pathway. | The journals of gerontology. Series A, Biological sciences and medical sciences 20070301 |
Intravenous azacitidine for MDS. | Clinical advances in hematology & oncology : H&O 20070301 |
The role of CpG methylation in cell type-specific expression of the aquaporin-5 gene. | Biochemical and biophysical research communications 20070223 |
Transplantation of autologous adipose-derived stem cells ameliorates cardiac function in rabbits with myocardial infarction. | Chinese medical journal 20070220 |
Igf-2r expression regulated by epigenetic modification and the locus of gene imprinting disrupted in cloned cattle. | Gene 20070215 |
Activity of decitabine, a hypomethylating agent, in chronic myelomonocytic leukemia. | Cancer 20070215 |
A role for bone morphogenetic protein-4 in adipocyte development. | Cell cycle (Georgetown, Tex.) 20070215 |
Methylation status of the Ep-CAM promoter region in human breast cancer cell lines and breast cancer tissue. | Cancer letters 20070208 |
Successful treatment of relapsed AML after allogeneic stem cell transplantation with azacitidine. | Leukemia research 20070201 |
Inhibition of MHC class II gene expression in uveal melanoma cells is due to methylation of the CIITA gene or an upstream activator. | Experimental and molecular pathology 20070201 |
Plasticity of Ly49g expression is due to epigenetics. | Molecular immunology 20070201 |
Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis. | Cell death and differentiation 20070201 |
Regulation of Cdx2 expression by promoter methylation, and effects of Cdx2 transfection on morphology and gene expression of human esophageal epithelial cells. | Carcinogenesis 20070201 |
Decitabine--bedside to bench. | Critical reviews in oncology/hematology 20070201 |
Decitabine and vitamin D3 differentially affect hematopoietic transcription factors to induce monocytic differentiation. | International journal of oncology 20070201 |
Epigenetic control of nuclear architecture. | Cellular and molecular life sciences : CMLS 20070201 |
Downregulation of RECK by promoter methylation correlates with lymph node metastasis in non-small cell lung cancer. | Cancer science 20070201 |
Application of mesenchymal stem cell-derived cardiomyocytes as bio-pacemakers: current status and problems to be solved. | Medical & biological engineering & computing 20070201 |
Dual role of DNA methylation inside and outside of CTCF-binding regions in the transcriptional regulation of the telomerase hTERT gene. | Nucleic acids research 20070201 |
Evidence that tumor necrosis factor-related apoptosis-inducing ligand induction by 5-Aza-2'-deoxycytidine sensitizes human breast cancer cells to adriamycin. | Cancer research 20070201 |
Effect of 6-azacytidine on the course of experimental adenoviral infection in newborn Syrian hamsters. | Journal of chemotherapy (Florence, Italy) 20070201 |
[Differentiation of QY1 bone marrow pluripotential mesenchymal stem cell line cells into cardiomyocytes and vascular endothelial cells in vitro]. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20070201 |
Recent experience with decitabine in MDS. | Clinical advances in hematology & oncology : H&O 20070201 |
Downregulation of RUNX3 and TES by hypermethylation in glioblastoma. | Oncogene 20070125 |
Update of the decitabine experience in higher risk myelodysplastic syndrome and analysis of prognostic factors associated with outcome. | Cancer 20070115 |
5-Aza-2'-deoxycytidine-mediated reductions in G9A histone methyltransferase and histone H3 K9 di-methylation levels are linked to tumor suppressor gene reactivation. | Oncogene 20070104 |
Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia. | Blood 20070101 |
Methylation status of a single CpG locus 3 bases upstream of TATA-box of receptor activator of nuclear factor-kappaB ligand (RANKL) gene promoter modulates cell- and tissue-specific RANKL expression and osteoclastogenesis. | Molecular endocrinology (Baltimore, Md.) 20070101 |
Inactivation of RASSF2A by promoter methylation correlates with lymph node metastasis in nasopharyngeal carcinoma. | International journal of cancer 20070101 |
Annexin-I as a potential target for green tea extract induced actin remodeling. | International journal of cancer 20070101 |
Epigenetic modulation of endogenous tumor suppressor expression in lung cancer xenografts suppresses tumorigenicity. | International journal of cancer 20070101 |
High-resolution mapping of DNA methylation in human genome using oligonucleotide tiling array. | Human genetics 20070101 |
Efficacy of DNA hypomethylating capacities of 5-aza-2'-deoxycytidine and its alpha anomer. | Pharmacological research 20070101 |
Relationship of aberrant DNA hypermethylation of CHFR with sensitivity to taxanes in endometrial cancer. | Oncology reports 20070101 |
The role of decitabine in the treatment of myelodysplastic syndromes. | Expert opinion on pharmacotherapy 20070101 |
DNA methylation promotes Aurora-B-driven phosphorylation of histone H3 in chromosomal subdomains. | Journal of cell science 20070101 |
Inhibition of breast cancer cell growth in vitro and in vivo: effect of restoration of Wwox expression. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070101 |
Growth of the protozoan parasite Entamoeba histolytica in 5-azacytidine has limited effects on parasite gene expression. | BMC genomics 20070101 |
Inhibition of histone deacetylation does not block resilencing of p16 after 5-aza-2'-deoxycytidine treatment. | Cancer research 20070101 |
Zebularine reactivates silenced E-cadherin but unlike 5-Azacytidine does not induce switching from latent to lytic Epstein-Barr virus infection in Burkitt's lymphoma Akata cells. | Molecular cancer 20070101 |
[Role of epigenetics in the carcinogenesis of head and neck carcinomas - possible new targeted therapy?]. | Laryngo- rhino- otologie 20070101 |
Identification of candidate methylation-responsive genes in ovarian cancer. | Molecular cancer 20070101 |
Cord blood in regenerative medicine: do we need immune suppression? | Journal of translational medicine 20070101 |
[Methylation of P15INK4B gene in patients with myelodysplastic syndromes and demethylating effects of drugs]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20070101 |
Risk-based management of myelodysplastic syndrome. | Oncology (Williston Park, N.Y.) 20070101 |
DAPK1 promoter hypermethylaiton in brain metastases and peripheral blood. | Neoplasma 20070101 |
Temporal dynamics of gene expression in the lung in a baboon model of E. coli sepsis. | BMC genomics 20070101 |
The effects of DNA methylation and histone deacetylase inhibitors on human papillomavirus early gene expression in cervical cancer, an in vitro and clinical study. | Virology journal 20070101 |
Replicative homeostasis III: implications for antiviral therapy and mechanisms of response and non-response. | Virology journal 20070101 |
Some facts and thoughts: p73 as a tumor suppressor gene in the network of tumor suppressors. | Molecular cancer 20070101 |
Lytic cycle switches of oncogenic human gammaherpesviruses. | Advances in cancer research 20070101 |
Human pluripotent embryonal carcinoma NTERA2 cl.D1 cells maintain their typical morphology in an angiomyogenic medium. | Journal of negative results in biomedicine 20070101 |
Simultaneously optimizing dose and schedule of a new cytotoxic agent. | Clinical trials (London, England) 20070101 |
DNA methyltransferase inhibitors for cancer therapy. | Cancer journal (Sudbury, Mass.) 20070101 |
Utilization of chromatin remodeling agents for lung cancer therapy. | Cancer journal (Sudbury, Mass.) 20070101 |
Methylation-mediated silencing of genes is not altered by selenium treatment of prostate cancer cells. | Anticancer research 20070101 |
Stringent and reproducible tetracycline-regulated transgene expression by site-specific insertion at chromosomal loci with pre-characterised induction characteristics. | BMC molecular biology 20070101 |
Current status of lupus genetics. | Arthritis research & therapy 20070101 |
The impact of 5-azacytidine on placental weight, glycoprotein pattern and proliferating cell nuclear antigen expression in rat placenta. | Placenta 20070101 |
New drugs: paliperidone, dasatinib, and decitabine. | Journal of the American Pharmacists Association : JAPhA 20070101 |
Diverse histone modifications on histone 3 lysine 9 and their relation to DNA methylation in specifying gene silencing. | BMC genomics 20070101 |
Genome position and gene amplification. | Genome biology 20070101 |
Trichostatin A effects on gene expression in the protozoan parasite Entamoeba histolytica. | BMC genomics 20070101 |
Transcriptional and epigenetic regulation of the integrin collagen receptor locus ITGA1-PELO-ITGA2. | Biochimica et biophysica acta 20070101 |
The impact of chromatin modifiers on the timing of locus replication in mouse embryonic stem cells. | Genome biology 20070101 |
Locus-specific ribosomal RNA gene silencing in nucleolar dominance. | PloS one 20070101 |
Decitabine and sickle cell disease: molecular therapy for a molecular disease. | Pediatric hematology and oncology 20070101 |
An unusual S-adenosylmethionine synthetase gene from dinoflagellate is methylated. | BMC molecular biology 20070101 |
The histone deacetylase inhibitor belinostat (PXD101) suppresses bladder cancer cell growth in vitro and in vivo. | Journal of translational medicine 20070101 |
DNA methylation state is preserved in the sperm-derived pronucleus of the pig zygote. | The International journal of developmental biology 20070101 |
Modulation of HLA-G expression. | Neoplasma 20070101 |
Chromosomal instability in Afrotheria: fragile sites, evolutionary breakpoints and phylogenetic inference from genome sequence assemblies. | BMC evolutionary biology 20070101 |
Somaclonal variation at the nucleotide sequence level in rice (Oryza sativa L.) as revealed by RAPD and ISSR markers, and by pairwise sequence analysis. | Journal of applied genetics 20070101 |
Endometrial regenerative cells: a novel stem cell population. | Journal of translational medicine 20070101 |
Chromatin, gene silencing and HIV latency. | Genome biology 20070101 |
Candidate tumor suppressor gene SLC5A8 is frequently down-regulated by promoter hypermethylation in prostate tumor. | Cancer detection and prevention 20070101 |
Epigenetic regulation of RhoB loss of expression in lung cancer. | BMC cancer 20070101 |
The effects of nucleoside analogues on promoter methylation of selected tumor suppressor genes in MCF-7 and MDA-MB-231 breast cancer cell lines. | Nucleosides, nucleotides & nucleic acids 20070101 |
Plasmid-based genetic modification of human bone marrow-derived stromal cells: analysis of cell survival and transgene expression after transplantation in rat spinal cord. | BMC biotechnology 20070101 |
Rice transposable elements are characterized by various methylation environments in the genome. | BMC genomics 20070101 |
Relationships between transcription, silver staining, and chromatin organization of nucleolar organizers in Secale cereale. | Protoplasma 20070101 |
A role for DNA methylation in regulating the growth suppressor PMEPA1 gene in prostate cancer. | Epigenetics 20070101 |
A sequential treatment of depsipeptide followed by 5-azacytidine enhances Gadd45beta expression in hepatocellular carcinoma cells. | Anticancer research 20070101 |
Targeted brain tumor treatment-current perspectives. | Drug target insights 20070101 |
Methylation of tumour suppressor genes APAF-1 and DAPK-1 and in vitro effects of demethylating agents in bladder and kidney cancer. | British journal of cancer 20061218 |
SPAN-XB core promoter sequence is regulated in myeloma cells by specific CpG dinucleotides associated with the MeCP2 protein. | International journal of cancer 20061215 |
5-Aza-2'-deoxycytidine and depsipeptide synergistically induce expression of BIK (BCL2-interacting killer). | Biochemical and biophysical research communications 20061215 |
RIZ1 is epigenetically inactivated by promoter hypermethylation in thyroid carcinoma. | Cancer 20061215 |
Low-dose decitabine and high-risk MDS. | Blood 20061215 |
Aberrant DNA demethylation in promoter region and aberrant expression of mRNA of PAX4 gene in hematologic malignancies. | Leukemia research 20061201 |
Downregulation of circadian clock genes in chronic myeloid leukemia: alternative methylation pattern of hPER3. | Cancer science 20061201 |
Inhibitors of DNA methylation and histone deacetylation independently relieve AML1/ETO-mediated lysozyme repression. | Journal of leukocyte biology 20061201 |
DNA methylation-dependent silencing of CST6 in human breast cancer cell lines. | Laboratory investigation; a journal of technical methods and pathology 20061201 |
Promoter hypermethylation-mediated down-regulation of LATS1 and LATS2 in human astrocytoma. | Neuroscience research 20061201 |
Cytotoxic activity of gemtuzumab ozogamicin (Mylotarg) in acute myeloid leukemia correlates with the expression of protein kinase Syk. | Leukemia 20061201 |
Chemotherapeutic agents for colorectal cancer with a defective mismatch repair system: the state of the art. | Cancer treatment reviews 20061201 |
Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers. | Gastroenterology 20061201 |
Epigenetic silencing of novel tumor suppressors in malignant melanoma. | Cancer research 20061201 |
5-Azacytidine induces changes in electrophysiological properties of human mesenchymal stem cells. | Cell research 20061201 |
A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies. | PLoS medicine 20061201 |
Association of DNA methylation and epigenetic inactivation of RASSF1A and beta-catenin with metastasis in small bowel carcinoid tumors. | Endocrine 20061201 |
[Expression of ER alpha in chemically induced MDA-MB-435 cells and its responsiveness to endocrine]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20061201 |
[Demethylation of estrogen receptor gene and its re-expression in estrogen receptor-negative breast]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20061201 |
Editorial foreword. | Therapeutics and clinical risk management 20061201 |
Azacytidine (Vidaza(R)) in the treatment of myelodysplastic syndromes. | Therapeutics and clinical risk management 20061201 |
Identification of novel genes associated with astrocytoma progression using suppression subtractive hybridization and real-time reverse transcription-polymerase chain reaction. | International journal of cancer 20061115 |
Phase 1/2 study of the combination of 5-aza-2'-deoxycytidine with valproic acid in patients with leukemia. | Blood 20061115 |
The expression of metastasis suppressor MIM/MTSS1 is regulated by DNA methylation. | International journal of cancer 20061115 |
Reprimo methylation is a potential biomarker of Barrett's-Associated esophageal neoplastic progression. | Clinical cancer research : an official journal of the American Association for Cancer Research 20061115 |
Decitabine (Dacogen) for myelodysplastic syndromes. | The Medical letter on drugs and therapeutics 20061106 |
Effect of histone deacetylase inhibitor LAQ824 on antineoplastic action of 5-Aza-2'-deoxycytidine (decitabine) on human breast carcinoma cells. | Cancer chemotherapy and pharmacology 20061101 |
Further studies on aberrant gene expression associated with arsenic-induced malignant transformation in rat liver TRL1215 cells. | Toxicology and applied pharmacology 20061101 |
Epigenetic regulation of human trophoblastic cell migration and invasion. | Endocrinology 20061101 |
Aberrant promoter methylation of the ABCG2 gene in renal carcinoma. | Molecular and cellular biology 20061101 |
Diagnostic utility of aberrant methylation of tissue factor pathway inhibitor 2 in pure pancreatic juice for pancreatic carcinoma. | Cancer science 20061101 |
Hypomethylation of the protein gene product 9.5 promoter region in gallbladder cancer and its relationship with clinicopathological features. | Cancer science 20061101 |
Hypermethylation of Cyclin D2 is associated with loss of mRNA expression and tumor development in prostate cancer. | Journal of molecular medicine (Berlin, Germany) 20061101 |
Epigenetic allele silencing unveils recessive RYR1 mutations in core myopathies. | American journal of human genetics 20061101 |
Global DNA and p53 region-specific hypomethylation in human colonic cells is induced by folate depletion and reversed by folate supplementation. | The Journal of nutrition 20061101 |
Human immunodeficiency virus impairs reverse cholesterol transport from macrophages. | PLoS biology 20061101 |
Alterations of the tumor suppressor gene ARLTS1 in ovarian cancer. | Cancer research 20061101 |
Interleukin-6 contributes to growth in cholangiocarcinoma cells by aberrant promoter methylation and gene expression. | Cancer research 20061101 |
Decitabine. | Nature reviews. Drug discovery 20061101 |
[Effect of spleen tyrosine kinase expression re-activation by inhibition of DNA methylation on oncogenesis growth of gastric cancer]. | Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20061101 |
Repair process of fetal brain after 5-azacytidine-induced damage. | The European journal of neuroscience 20061101 |
Targeting the epigenome for the treatment of thoracic malignancies. | Thoracic surgery clinics 20061101 |
Genetic abnormalities as targets for molecular therapies in myelodysplastic syndromes. | Annals of the New York Academy of Sciences 20061101 |
Epigenetic inactivation of EGFR by CpG island hypermethylation in cancer. | Cancer biology & therapy 20061101 |
Methylation of the mouse DIx5 and Osx gene promoters regulates cell type-specific gene expression. | Molecules and cells 20061031 |
[Expression of S100A2 in secondarily radioresistant pancreatic cancer cells and significance thereof]. | Zhonghua yi xue za zhi 20061031 |
Expression of Lea in gastric cancer cell lines depends on FUT3 expression regulated by promoter methylation. | Cancer letters 20061028 |
Epigenetic cancer therapy makes headway. | Journal of the National Cancer Institute 20061018 |
MUC2 expression is regulated by histone H3 modification and DNA methylation in pancreatic cancer. | International journal of cancer 20061015 |
DNA mismatch repair as an effector for promoting phorbol ester-induced apoptotic DNA damage and cell killing: implications in tumor promotion. | International journal of cancer 20061015 |
Treatment of acute myelogenous leukemia with outpatient azacitidine. | Cancer 20061015 |
Reaction of hydroxyl radicals with azacytosines: a pulse radiolysis and theoretical study. | The journal of physical chemistry. A 20061012 |
Effect of aging on the pluripotential capacity of human CD105+ mesenchymal stem cells. | European journal of heart failure 20061001 |
Analysis of genes upregulated by the demethylating agent 5-aza-2'-deoxycytidine in gastric cancer cell lines. | International journal of cancer 20061001 |
Differentially methylated alleles in a distinct region of the human interleukin-1alpha promoter are associated with allele-specific expression of IL-1alpha in CD4+ T cells. | Blood 20061001 |
Epigenetic regulation of the rice retrotransposon Tos17. | Molecular genetics and genomics : MGG 20061001 |
PML-RARalpha and AML1-ETO translocations are rarely associated with methylation of the RARbeta2 promoter. | Annals of hematology 20061001 |
Epigenetic regulation of maspin expression in the human placenta. | Molecular human reproduction 20061001 |
Genetic analysis and epigenetic silencing of At4CL1 and At4CL2 expression in transgenic Arabidopsis. | Biotechnology journal 20061001 |
An EBF3-mediated transcriptional program that induces cell cycle arrest and apoptosis. | Cancer research 20061001 |
Phase I study of decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura. | Clinical cancer research : an official journal of the American Association for Cancer Research 20061001 |
Improved DNA methylation analysis via enrichment of demethylated cells expressing an X-inactivated transgene. | BioTechniques 20061001 |
DNA hypermethylation of myeloid cells, a novel therapeutic target in MDS and AML. | Current pharmaceutical biotechnology 20061001 |
Proteomic profiling of rat bone marrow mesenchymal stem cells induced by 5-azacytidine. | Stem cells and development 20061001 |
[SHP-1 gene's methylation status of Daudi lymphoma cell and the demethylation effect of 5-aza-2'-deoxycytidine]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20061001 |
Promoter hypomethylation and reactivation of MAGE-A1 and MAGE-A3 genes in colorectal cancer cell lines and cancer tissues. | World journal of gastroenterology 20060921 |
Silencing of the UCHL1 gene in human colorectal and ovarian cancers. | International journal of cancer 20060915 |
B29 gene silencing in pituitary cells is regulated by its 3' enhancer. | Journal of molecular biology 20060915 |
High-frequency promoter hypermethylation of the deleted in liver cancer-1 gene in multiple myeloma. | Journal of clinical pathology 20060901 |
DNA methylation levels in porcine fetal fibroblasts induced by an inhibitor of methylation, 5-azacytidine. | Cell and tissue research 20060901 |
Regulation of the expression of human organic anion transporter 3 by hepatocyte nuclear factor 1alpha/beta and DNA methylation. | Molecular pharmacology 20060901 |
Synergic antiproliferative effect of DNA methyltransferase inhibitor in combination with anticancer drugs in gastric carcinoma. | Cancer science 20060901 |
Regulation of DNA methylation on the expression of the FHIT gene contributes to cervical carcinoma cell tumorigenesis. | Oncology reports 20060901 |
Restoration of shp1 expression by 5-AZA-2'-deoxycytidine is associated with downregulation of JAK3/STAT3 signaling in ALK-positive anaplastic large cell lymphoma. | Leukemia 20060901 |
Role of cyclic nucleotides in fetal hemoglobin induction in cultured CD34+ cells. | Experimental hematology 20060901 |
Enhancement of sodium/iodide symporter expression in thyroid and breast cancer. | Endocrine-related cancer 20060901 |
Expression profiling identifies three pathways altered in cellular immortalization: interferon, cell cycle, and cytoskeleton. | The journals of gerontology. Series A, Biological sciences and medical sciences 20060901 |
The genomics of new drugs in sickle cell disease. | Pharmacogenomics 20060901 |
Asparaginase (native ASNase or pegylated ASNase) in the treatment of acute lymphoblastic leukemia. | International journal of nanomedicine 20060901 |
5-Aza-2'-deoxycytidine and IFN-gamma cooperate to sensitize for TRAIL-induced apoptosis by upregulating caspase-8. | Oncogene 20060824 |
Further analysis of trials with azacitidine in patients with myelodysplastic syndrome: studies 8421, 8921, and 9221 by the Cancer and Leukemia Group B. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060820 |
Oncogenic HRAS suppresses clusterin expression through promoter hypermethylation. | Oncogene 20060810 |
Overcoming resistance to interferon-induced apoptosis of renal carcinoma and melanoma cells by DNA demethylation. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060810 |
Localized methylation in the key regulator gene endothelin-1 is associated with cell type-specific transcriptional silencing. | FEBS letters 20060807 |
Trisomy 19 as the sole chromosomal abnormality in proliferative chronic myelomonocytic leukemia. | Leukemia research 20060801 |
p21Waf1/Cip1 plays a critical role in modulating senescence through changes of DNA methylation. | Journal of cellular biochemistry 20060801 |
Galectin-1 induces skeletal muscle differentiation in human fetal mesenchymal stem cells and increases muscle regeneration. | Stem cells (Dayton, Ohio) 20060801 |
Epigenetic inactivation of the dioxin-responsive cytochrome P4501A1 gene in human prostate cancer. | Cancer research 20060801 |
Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma. | Cancer research 20060801 |
Phase I trial of sequential low-dose 5-aza-2'-deoxycytidine plus high-dose intravenous bolus interleukin-2 in patients with melanoma or renal cell carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060801 |
Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer. | Oncogene 20060706 |
The miscarriage-associated HLA-G -725G allele influences transcription rates in JEG-3 cells. | Human reproduction (Oxford, England) 20060701 |
LUMA (LUminometric Methylation Assay)--a high throughput method to the analysis of genomic DNA methylation. | Experimental cell research 20060701 |
Second complete remission in an elderly patient with acute myeloid leukemia retreated with decitabine. | American journal of hematology 20060701 |
A role for DNA hypomethylation and histone acetylation in maintaining allele-specific expression of mouse NKG2A in developing and mature NK cells. | Journal of immunology (Baltimore, Md. : 1950) 20060701 |
Association between enhanced type I collagen expression and epigenetic repression of the FLI1 gene in scleroderma fibroblasts. | Arthritis and rheumatism 20060701 |
RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer. | Cancer research 20060701 |
Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma. | Cancer research 20060701 |
Estrogen receptor-alpha methylation predicts melanoma progression. | Cancer research 20060701 |
Methylation of neutral endopeptidase 24.11 promoter in rat hepatocellular carcinoma. | Cancer science 20060701 |
[Effect of the epimutagen 5-azacytidine on the structure of floral-stalk metameres in sugar beet (Beta vulgaris L)]. | Genetika 20060701 |
Bone marrow cells for cardiac regeneration and repair: current status and issues. | Expert review of cardiovascular therapy 20060701 |
Managing patients with low-risk MDS. | Clinical advances in hematology & oncology : H&O 20060701 |
Regional hypermethylation and global hypomethylation are associated with altered chromatin conformation and histone acetylation in colorectal cancer. | International journal of cancer 20060615 |
Mouse follicular and marginal zone B cells show differential expression of Dnmt3a and sensitivity to 5'-azacytidine. | Immunology letters 20060615 |
Combined DNA methyltransferase and histone deacetylase inhibition in the treatment of myeloid neoplasms. | Cancer research 20060615 |
Restoration of tamoxifen sensitivity in estrogen receptor-negative breast cancer cells: tamoxifen-bound reactivated ER recruits distinctive corepressor complexes. | Cancer research 20060615 |
Methylation of the ATM promoter in glioma cells alters ionizing radiation sensitivity. | Biochemical and biophysical research communications 20060609 |
GnT-V expression and metastatic phenotypes in macrophage-melanoma fusion hybrids is down-regulated by 5-Aza-dC: evidence for methylation sensitive, extragenic regulation of GnT-V transcription. | Gene 20060607 |
Sequential gene expression changes in cancer cell lines after treatment with the demethylation agent 5-Aza-2'-deoxycytidine. | Cancer 20060601 |
Clinical management of myelodysplastic syndromes with interstitial deletion of chromosome 5q. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060601 |
Differential regulation of the alcohol dehydrogenase 1B (ADH1B) and ADH1C genes by DNA methylation and histone deacetylation. | Alcoholism, clinical and experimental research 20060601 |
Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. | Cancer cell 20060601 |
Multiple mechanisms underlie the aberrant expression of the human kallikrein 6 gene in breast cancer. | Biological chemistry 20060601 |
The epigenetic basis for the aberrant expression of kallikreins in human cancers. | Biological chemistry 20060601 |
Targeted reduction of the DNA methylation level with 5-azacytidine promotes excision of the medaka fish Tol2 transposable element. | Genetical research 20060601 |
[Disfigurement of p16INK4A gene expression in development of ovarian cancer and the mechanism]. | Zhonghua fu chan ke za zhi 20060601 |
Methylation of the human papillomavirus-18 L1 gene: a biomarker of neoplastic progression? | Virology 20060525 |
Effects of endothelin-1 on differentiation of cardiac myocyte induced from rabbit bone marrow stromal cells. | Chinese medical journal 20060520 |
Alterations of the Wnt signaling pathway during the neoplastic progression of Barrett's esophagus. | Oncogene 20060518 |
Excess methionine suppresses the methylation cycle and inhibits neural tube closure in mouse embryos. | FEBS letters 20060515 |
Identification of novel target genes by an epigenetic reactivation screen of renal cancer. | Cancer research 20060515 |
DNA methylation changes after 5-aza-2'-deoxycytidine therapy in patients with leukemia. | Cancer research 20060515 |
Regulation of high molecular weight-melanoma associated antigen (HMW-MAA) gene expression by promoter DNA methylation in human melanoma cells. | Oncogene 20060511 |
Lactate dehydrogenase-B is silenced by promoter hypermethylation in human prostate cancer. | Oncogene 20060511 |
Cell cycle progression is required for nuclear migration of neural progenitor cells. | Brain research 20060509 |
The dioxin receptor is silenced by promoter hypermethylation in human acute lymphoblastic leukemia through inhibition of Sp1 binding. | Carcinogenesis 20060501 |
Preferential methylation of Wnt inhibitory factor-1 in acute promyelocytic leukemia: an independent poor prognostic factor. | Leukemia 20060501 |
Epigenetic silencing of interferon-inducible genes is implicated in interferon resistance of hepatitis C virus replicon-harboring cells. | Journal of hepatology 20060501 |
Aberrant methylation of RASGRF2 and RASSF1A in human non-small cell lung cancer. | Oncology reports 20060501 |
Abnormal activation of the synuclein-gamma gene in hepatocellular carcinomas by epigenetic alteration. | International journal of oncology 20060501 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
Imprinting at the SMPD1 locus: implications for acid sphingomyelinase-deficient Niemann-Pick disease. | American journal of human genetics 20060501 |
Nickel ions increase histone H3 lysine 9 dimethylation and induce transgene silencing. | Molecular and cellular biology 20060501 |
Epigenetic inactivation of Betaig-h3 gene in human cancer cells. | Cancer research 20060501 |
Promoter demethylation and histone acetylation mediate gene expression of MAGE-A1, -A2, -A3, and -A12 in human cancer cells. | Molecular cancer research : MCR 20060501 |
[Transcription regulation of 5-Aza-2'-deoxycytidine on maspin gene demethylation in RKO human colorectal cell line]. | Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20060501 |
New strategies in chronic myeloid leukemia. | International journal of hematology 20060501 |
[Further improving the standard of treatment for chronic myeloid leukemia]. | Zhonghua nei ke za zhi 20060501 |
Review: recent clinical trials in epigenetic therapy. | Reviews on recent clinical trials 20060501 |
Epigenetics as a mechanism driving polygenic clinical drug resistance. | British journal of cancer 20060424 |
Site-specific DNA methylation by a complex of PU.1 and Dnmt3a/b. | Oncogene 20060420 |
CpG methylation suppresses transcriptional activity of human syncytin-1 in non-placental tissues. | Experimental cell research 20060415 |
Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study. | Cancer 20060415 |
Drug therapy for myelodysplastic syndrome: building evidence for action. | Cancer 20060415 |
Superiority of prolonged low-dose azanucleoside administration? Results of 5-aza-2'-deoxycytidine retreatment in high-risk myelodysplasia patients. | Cancer 20060415 |
Loss of interleukin-2-dependency in HTLV-I-infected T cells on gene silencing of thioredoxin-binding protein-2. | Oncogene 20060406 |
Phenotypic and functional changes of human melanoma xenografts induced by DNA hypomethylation: immunotherapeutic implications. | Journal of cellular physiology 20060401 |
Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma. | Cell death and differentiation 20060401 |
Promoter hypomethylation of Toll-like receptor-2 gene is associated with increased proinflammatory response toward bacterial peptidoglycan in cystic fibrosis bronchial epithelial cells. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060401 |
Pathophysiologically based drug treatment of sickle cell disease. | Trends in pharmacological sciences 20060401 |
Rapid demethylation of the IFN-gamma gene occurs in memory but not naive CD8 T cells. | Journal of immunology (Baltimore, Md. : 1950) 20060401 |
A single nucleotide polymorphism chip-based method for combined genetic and epigenetic profiling: validation in decitabine therapy and tumor/normal comparisons. | Cancer research 20060401 |
Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state. | Cancer research 20060401 |
PGP9.5 methylation in diffuse-type gastric cancer. | Cancer research 20060401 |
Gene promoter hypermethylation in mouse lung tumors. | Molecular cancer research : MCR 20060401 |
Altered nuclear receptor corepressor expression attenuates vitamin D receptor signaling in breast cancer cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060401 |
Enhanced differentiation of human embryonic stem cells into cardiomyocytes by combining hanging drop culture and 5-azacytidine treatment. | Differentiation; research in biological diversity 20060401 |
Myogenesis in hemopoietic tissue mesenchymal stem cell culture. | Bulletin of experimental biology and medicine 20060401 |
[Myelodysplastic syndromes--new treatment options]. | Medizinische Klinik (Munich, Germany : 1983) 20060322 |
SPAN-Xb expression in myeloma cells is dependent on promoter hypomethylation and can be upregulated pharmacologically. | International journal of cancer 20060315 |
Epigenetic processes play a major role in B-cell-specific gene silencing in classical Hodgkin lymphoma. | Blood 20060315 |
Epigenetic modulation of tumor suppressor CCAAT/enhancer binding protein alpha activity in lung cancer. | Journal of the National Cancer Institute 20060315 |
Irinotecan inactivation is modulated by epigenetic silencing of UGT1A1 in colon cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060315 |
Tumor-specific expression of the novel cytochrome P450 enzyme, CYP2W1. | Biochemical and biophysical research communications 20060310 |
Wnt signaling activation and WIF-1 silencing in nasopharyngeal cancer cell lines. | Biochemical and biophysical research communications 20060310 |
Aberrant expression of N-acetylglucosaminyltransferase-IVa and IVb (GnT-IVa and b) in pancreatic cancer. | Biochemical and biophysical research communications 20060310 |
Reverting cholesterol auxotrophy of NS0 cells by altering epigenetic gene silencing. | Biotechnology and bioengineering 20060305 |
Treatment of myelodysplastic syndrome with a DNA methyltransferase inhibitor: lack of evidence for induction of chromosomal instability. | Leukemia research 20060301 |
Multi-gene epigenetic silencing of tumor suppressor genes in T-cell lymphoma cells; delayed expression of the p16 protein upon reversal of the silencing. | Leukemia research 20060301 |
Molecular inhibition of histone deacetylation results in major enhancement of the production of IL-1beta in response to LPS. | American journal of physiology. Endocrinology and metabolism 20060301 |
RAS-mediated epigenetic inactivation of OPCML in oncogenic transformation of human ovarian surface epithelial cells. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301 |
Epigenetic suppression of secreted frizzled related protein 1 (SFRP1) expression in human breast cancer. | Cancer biology & therapy 20060301 |
Promoter hypermethylation of FANCF plays an important role in the occurrence of ovarian cancer through disrupting Fanconi anemia-BRCA pathway. | Cancer biology & therapy 20060301 |
Cell cycle and cell death regulation of neural progenitor cells in the 5-azacytidine (5AzC)-treated developing fetal brain. | Experimental neurology 20060301 |
A novel terminal differentiation model of human articular chondrocytes in three-dimensional cultures mimicking chondrocytic changes in osteoarthritis. | Cell biology international 20060301 |
Epigenetics: the science of change. | Environmental health perspectives 20060301 |
Loss of expression of type IV collagen alpha5 and alpha6 chains in colorectal cancer associated with the hypermethylation of their promoter region. | The American journal of pathology 20060301 |
Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines. | Cancer research 20060301 |
Effect of methylation-associated silencing of the death-associated protein kinase gene on nasopharyngeal carcinoma. | Anti-cancer drugs 20060301 |
Aberrant methylation and deacetylation of deleted in liver cancer-1 gene in prostate cancer: potential clinical applications. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060301 |
Effect of 5-aza-2'-deoxycytidine (Dacogen) on covalent histone modifications of chromatin associated with the epsilon-, gamma-, and beta-globin promoters in Papio anubis. | Experimental hematology 20060301 |
Meiotically stable natural epialleles of Sadhu, a novel Arabidopsis retroposon. | PLoS genetics 20060301 |
Epigenetic repression of RASSF1A but not CASP8 in supratentorial PNET (sPNET) and atypical teratoid/rhabdoid tumors (AT/RT) of childhood. | Oncogene 20060216 |
Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation. | Oncogene 20060216 |
PDLIM4 repression by hypermethylation as a potential biomarker for prostate cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060215 |
In vitro cardiomyogenic potential of human umbilical vein-derived mesenchymal stem cells. | Biochemical and biophysical research communications 20060210 |
Expression and methylation pattern of TSLC1 cascade genes in lung carcinomas. | Oncogene 20060209 |
Cytogenetic and expression profiles associated with transformation to androgen-resistant prostate cancer. | The Prostate 20060201 |
Pilot study of combination transcriptional modulation therapy with sodium phenylbutyrate and 5-azacytidine in patients with acute myeloid leukemia or myelodysplastic syndrome. | Leukemia 20060201 |
Homozygous deletion and reduced expression of the DOCK8 gene in human lung cancer. | International journal of oncology 20060201 |
A novel mechanism for acquired cisplatin-resistance: suppressed translation of death-associated protein kinase mRNA is insensitive to 5-aza-2'-deoxycitidine and trichostatin in cisplatin-resistant cervical squamous cancer cells. | International journal of oncology 20060201 |
Decreased STAT1 expression by promoter methylation in squamous cell carcinogenesis. | Journal of the National Cancer Institute 20060201 |
Expansion of human umbilical cord blood SCID-repopulating cells using chromatin-modifying agents. | Experimental hematology 20060201 |
Inhibition of DNA methylation increases follistatin expression and secretion in the human adrenocortical cell line NCI-H295R. | The Journal of endocrinology 20060201 |
Aberrant methylation of the eyes absent 4 gene in ulcerative colitis-associated dysplasia. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20060201 |
The hematologic response to anti-apoptotic cytokine therapy: results of pentoxifylline, ciprofloxacin, and dexamethasone treatment for patients with myelodysplastic syndrome. | Journal of Korean medical science 20060201 |
Angiostatic activity of DNA methyltransferase inhibitors. | Molecular cancer therapeutics 20060201 |
Differential transcription of ovine herpesvirus 2 genes in lymphocytes from reservoir and susceptible species. | Virus genes 20060201 |
Characterisation of the GRAF gene promoter and its methylation in patients with acute myeloid leukaemia and myelodysplastic syndrome. | British journal of cancer 20060130 |
Epigenetics provides a new generation of oncogenes and tumour-suppressor genes. | British journal of cancer 20060130 |
CpG island methylation and expression of the secreted frizzled-related protein gene family in chronic lymphocytic leukemia. | Cancer research 20060115 |
De novo induction of a cancer/testis antigen by 5-aza-2'-deoxycytidine augments adoptive immunotherapy in a murine tumor model. | Cancer research 20060115 |
Epigenetic inactivation of Wnt inhibitory factor-1 plays an important role in bladder cancer through aberrant canonical Wnt/beta-catenin signaling pathway. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060115 |
Epigenetic silencing of AXIN2 in colorectal carcinoma with microsatellite instability. | Oncogene 20060105 |
5-Aza-2'-deoxycytidine (decitabine) can relieve p21WAF1 repression in human acute myeloid leukemia by a mechanism involving release of histone deacetylase 1 (HDAC1) without requiring p21WAF1 promoter demethylation. | Leukemia research 20060101 |
Epigenetic regulation of lentiviral transgene vectors in a large animal model. | Molecular therapy : the journal of the American Society of Gene Therapy 20060101 |
Effects of epigenetic modulation on reporter gene expression: implications for stem cell imaging. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060101 |
Effects of 5-aza-2'-deoxycytidine on proliferation, differentiation and p15/INK4b regulation of human hematopoietic progenitor cells. | Leukemia 20060101 |
Correlations between the activities of 19 anti-tumor agents and the intracellular glutathione concentrations in a panel of 14 human cancer cell lines: comparisons with the National Cancer Institute data. | Anti-cancer drugs 20060101 |
Promoter methylation reduces C/EBPdelta (CEBPD) gene expression in the SUM-52PE human breast cancer cell line and in primary breast tumors. | Breast cancer research and treatment 20060101 |
Aberrant promoter methylation of EDNRB in lung cancer in Taiwan. | Oncology reports 20060101 |
Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2'-deoxycytidine treatment and oligonucleotide microarray. | Cancer science 20060101 |
An active DNA transposon nDart causing leaf variegation and mutable dwarfism and its related elements in rice. | The Plant journal : for cell and molecular biology 20060101 |
Inhibition of DNA methyltransferase activity prevents tumorigenesis in a mouse model of prostate cancer. | Cancer research 20060101 |
A pharmacodynamic study of 5-azacytidine in the P39 cell line. | Experimental hematology 20060101 |
Reverting estrogen-receptor-negative phenotype in HER-2-overexpressing advanced breast cancer patients exposed to trastuzumab plus chemotherapy. | Breast cancer research : BCR 20060101 |
Current therapy of sickle cell disease. | Haematologica 20060101 |
Discovery of novel methylation biomarkers in cervical carcinoma by global demethylation and microarray analysis. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20060101 |
Epigenetics and airways disease. | Respiratory research 20060101 |
Hydralazine target: from blood vessels to the epigenome. | Journal of translational medicine 20060101 |
Epigenetic regulation: DNA confers identity but is not enough to maintain it. | Genome biology 20060101 |
Myelodysplasia: when to treat and how. | Best practice & research. Clinical haematology 20060101 |
Characterization of decomposition products and preclinical and low dose clinical pharmacokinetics of decitabine (5-aza-2'-deoxycytidine) by a new liquid chromatography/tandem mass spectrometry quantification method. | Rapid communications in mass spectrometry : RCM 20060101 |
Effect of 5-azacytidine on the protein expression of porcine bone marrow mesenchymal stem cells in vitro. | Genomics, proteomics & bioinformatics 20060101 |
Immunodeficiency, centromeric region instability, facial anomalies syndrome (ICF). | Orphanet journal of rare diseases 20060101 |
Decitabine: in myelodysplastic syndromes. | Drugs 20060101 |
Decitabine in myelodysplastic syndromes: viewpoints. | Drugs 20060101 |
Slow, stochastic transgene repression with properties of a timer. | Genome biology 20060101 |
The p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancers. | Molecular cancer 20060101 |
Effects of autologous bone marrow stem cell transplantation on beta-adrenoceptor density and electrical activation pattern in a rabbit model of non-ischemic heart failure. | Journal of cardiothoracic surgery 20060101 |
Clinical evaluation of E-cadherin expression and its regulation mechanism in epithelial ovarian cancer. | Clinical & experimental metastasis 20060101 |
Methylation mediated silencing of TMS1/ASC gene in prostate cancer. | Molecular cancer 20060101 |
Epigenetics of gene expression in human hepatoma cells: expression profiling the response to inhibition of DNA methylation and histone deacetylation. | BMC genomics 20060101 |
The potential regulation of L1 mobility by RNA interference. | Journal of biomedicine & biotechnology 20060101 |
Global DNA hypermethylation-associated cancer chemotherapy resistance and its reversion with the demethylating agent hydralazine. | Journal of translational medicine 20060101 |
MDS: navigating the complex course. | ONS news 20060101 |
Pharmacologic reductions of total tau levels; implications for the role of microtubule dynamics in regulating tau expression. | Molecular neurodegeneration 20060101 |
The impact of iron overload and its treatment on quality of life: results from a literature review. | Health and quality of life outcomes 20060101 |
Inhibitors of histone deacetylases and DNA methyltransferases alter imprinted gene regulation in embryonic stem cells. | Cloning and stem cells 20060101 |
Tumor suppressor gene methylation in follicular lymphoma: a comprehensive review. | Molecular cancer 20060101 |
5' long terminal repeat (LTR)-selective methylation of latently infected HIV-1 provirus that is demethylated by reactivation signals. | Retrovirology 20060101 |
Alteration of DNA methylation status in K562 and MCF-7 cancer cell lines by nucleoside analogues. | Nucleosides, nucleotides & nucleic acids 20060101 |
Establishment of cell lines that exhibit correct ontogenic stage-specific gene expression profiles from tissues of yeast artificial chromosome transgenic mice using chemically induced growth signals. | Methods in molecular biology (Clifton, N.J.) 20060101 |
Transcriptional and post-transcriptional regulation of retrotransposons IAP and MuERV-L affect pluripotency of mice ES cells. | Reproductive biology and endocrinology : RB&E 20060101 |
Induction of fetal hemoglobin in the treatment of sickle cell disease. | Hematology. American Society of Hematology. Education Program 20060101 |
Clinical issues in the management of patients with myelodysplasia. | Hematology. American Society of Hematology. Education Program 20060101 |
Can 5-azacytidine convert the adult stem cells into cardiomyocytes? A brief overview. | Archives of physiology and biochemistry 20060101 |
A proof-of-principle study of epigenetic therapy added to neoadjuvant doxorubicin cyclophosphamide for locally advanced breast cancer. | PloS one 20060101 |
New treatment for rare bone marrow condition. | FDA consumer 20060101 |
[Effect of 5-azacitidine on flower stalk branching in sugar beet (Beta vulgaris L.)]. | TSitologiia i genetika 20060101 |
Methylation status of genes upregulated by demethylating agent 5-aza-2'-deoxycytidine in hepatocellular carcinoma. | Oncology 20060101 |
Genetic and epigenetic alterations of LTF at 3p21.3 in nasopharyngeal carcinoma. | Oncology research 20060101 |
The synergistic effect of 5-aza-2'-deoxycytidine and 5-fluorouracil on drug-resistant tumors. | Oncology 20060101 |
5-Aza-2'-deoxycytidine induces retinoic acid receptor-beta(2) demethylation and growth inhibition in esophageal squamous carcinoma cells. | Cancer letters 20051218 |
Inhibition of DNA methylation sensitizes glioblastoma for tumor necrosis factor-related apoptosis-inducing ligand-mediated destruction. | Cancer research 20051215 |
Alkaline induces metallothionein gene expression and potentiates cell proliferation in Chinese hamster ovary cells. | Journal of cellular physiology 20051201 |
Histone modification in the TGFbetaRII gene promoter and its significance for responsiveness to HDAC inhibitor in lung cancer cell lines. | Molecular carcinogenesis 20051201 |
Decitabine activates specific caspases downstream of p73 in myeloid leukemia. | Annals of hematology 20051201 |
An epigenetic approach to the treatment of advanced MDS; the experience with the DNA demethylating agent 5-aza-2'-deoxycytidine (decitabine) in 177 patients. | Annals of hematology 20051201 |
Decitabine: a historical review of the development of an epigenetic drug. | Annals of hematology 20051201 |
Butyrates and decitabine cooperate to induce histone acetylation and granulocytic maturation of t(8;21) acute myeloid leukemia blasts. | Annals of hematology 20051201 |
Clinical experience with decitabine in North American patients with myelodysplastic syndrome. | Annals of hematology 20051201 |
In vivo effects of decitabine in myelodysplasia and acute myeloid leukemia: review of cytogenetic and molecular studies. | Annals of hematology 20051201 |
Quantification of outpatient management and hospitalization of patients with high-risk myelodysplastic syndrome treated with low-dose decitabine. | Annals of hematology 20051201 |
The hematopathological basis for studying effects of the demethylating agent 5-aza-2'-deoxycytidine (decitabine) in myelodysplasia. | Annals of hematology 20051201 |
5-Azacytidine decreases fragmentation of nuclear DNA and pigment formation in first leaf cells of barley seedlings. | Cell biology international 20051201 |
BRCA1 promoter methylation in sporadic breast cancer is associated with reduced BRCA1 copy number and chromosome 17 aneusomy. | Cancer research 20051201 |
Methylation inhibitor therapy in the treatment of myelodysplastic syndrome. | Nature clinical practice. Oncology 20051201 |
Optimizing therapy with methylation inhibitors in myelodysplastic syndromes: dose, duration, and patient selection. | Nature clinical practice. Oncology 20051201 |
Inhibitors of DNA methylation: beyond myelodysplastic syndromes. | Nature clinical practice. Oncology 20051201 |
DNA methylation and gene silencing in cancer. | Nature clinical practice. Oncology 20051201 |
[The synergistic inhibitory effect of 5-aza-2-deoxycytidine and Tamoxifen on estrogen receptor alpha negative breast cancer cell lines in vitro]. | Zhonghua wai ke za zhi [Chinese journal of surgery] 20051201 |
Epigenetic and classical activation of Entamoeba histolytica heat shock protein 100 (EHsp100) expression. | FEBS letters 20051121 |
RARbeta1': primed to fight retinoid resistance in lung carcinogenesis. | Journal of the National Cancer Institute 20051116 |
A novel retinoic acid receptor beta isoform and retinoid resistance in lung carcinogenesis. | Journal of the National Cancer Institute 20051116 |
Hypermethylation of the prostacyclin synthase (PTGIS) promoter is a frequent event in colorectal cancer and associated with aneuploidy. | Oncogene 20051110 |
{gamma}-Globin gene expression in chemical inducer of dimerization (CID)-dependent multipotential cells established from human {beta}-globin locus yeast artificial chromosome ({beta}-YAC) transgenic mice. | The Journal of biological chemistry 20051104 |
Multiple markers for melanoma progression regulated by DNA methylation: insights from transcriptomic studies. | Carcinogenesis 20051101 |
Hyperacetylation enhances the growth-inhibitory effect of all-trans retinoic acid by the restoration of retinoic acid receptor beta expression in head and neck squamous carcinoma (HNSCC) cells. | Cancer chemotherapy and pharmacology 20051101 |
Management of patients with higher risk myelodysplastic syndromes. | Critical reviews in oncology/hematology 20051101 |
The epigenome as a molecular marker and target. | Cancer 20051101 |
Fusion of bone marrow-derived stem cells with cardiomyocytes in a heterologous in vitro model. | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20051101 |
Pig islet xenotransplantation: activation of porcine endogenous retrovirus in the immediate post-transplantation period. | Xenotransplantation 20051101 |
Increasing donor age adversely impacts beneficial effects of bone marrow but not smooth muscle myocardial cell therapy. | American journal of physiology. Heart and circulatory physiology 20051101 |
Tissue-specific and de novo promoter methylation of the mouse glucose transporter 2. | Biological & pharmaceutical bulletin 20051101 |
The methyltransferase inhibitor 5-aza-2-deoxycytidine induces apoptosis via induction of 15-lipoxygenase-1 in colorectal cancer cells. | Molecular cancer therapeutics 20051101 |
DNA methylation is not necessary for the inactivation of the Tam3 transposon at non-permissive temperature in Antirrhinum. | Journal of plant physiology 20051101 |
[Growth inhibition and demethylation by a component of natural drug, CDP, in cancer cell lines]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20051101 |
New agents in the treatment of MDS. | Clinical advances in hematology & oncology : H&O 20051101 |
Passage-restricted differentiation potential of mesenchymal stem cells into cardiomyocyte-like cells. | Biochemical and biophysical research communications 20051028 |
DNA methylation of genes linked with retinoid signaling in gastric carcinoma: expression of the retinoid acid receptor beta, cellular retinol-binding protein 1, and tazarotene-induced gene 1 genes is associated with DNA methylation. | Cancer 20051015 |
The DNA demethylating 5-azaC induces endoreduplication in cultured Chinese hamster cells. | Mutation research 20051015 |
Hypermethylation of 18S and 28S ribosomal DNAs predicts progression-free survival in patients with ovarian cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20051015 |
Differential promotion of glutamate transporter expression and function by glucocorticoids in astrocytes from various brain regions. | The Journal of biological chemistry 20051014 |
Estimating the total mouse DNA methylation according to the B1 repetitive elements. | Biochemical and biophysical research communications 20051007 |
Promoter CpG hypermethylation and downregulation of DICE1 expression in prostate cancer. | Oncogene 20051006 |
DNA methylation increases throughout Arabidopsis development. | Planta 20051001 |
Epigenetic-mediated upregulation of progesterone receptor B gene in endometrial cancer cell lines. | Gynecologic oncology 20051001 |
The role of T-fimbrin in the response to DNA damage: silencing of T-fimbrin by small interfering RNA sensitizes human liver cancer cells to DNA-damaging agents. | International journal of oncology 20051001 |
Frequent hemizygous deletion at 1p36 and hypermethylation downregulate RUNX3 expression in human lung cancer cell lines. | Oncology reports 20051001 |
5-aza-2'-deoxycytidine sensitizes hepatoma and pancreatic cancer cell lines. | Oncology reports 20051001 |
5-azacytidine and decitabine monotherapies of myelodysplastic disorders. | The Annals of pharmacotherapy 20051001 |
Trapped in action: direct visualization of DNA methyltransferase activity in living cells. | Nature methods 20051001 |
Potentiation of in vitro ara-C cytotoxicity by ribonucleotide reductase inhibitors, cyclin-dependent kinase modulators and the DNA repair inhibitor aphidicolin in paediatric acute myeloid leukaemia. | British journal of haematology 20051001 |
Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy. | Clinical cancer research : an official journal of the American Association for Cancer Research 20051001 |
Activator protein 2alpha status determines the chemosensitivity of cancer cells: implications in cancer chemotherapy. | Cancer research 20051001 |
The cell cycle checkpoint gene Rad9 is a novel oncogene activated by 11q13 amplification and DNA methylation in breast cancer. | Cancer research 20051001 |
Epigenetic drugs: a longstanding story. | Seminars in oncology 20051001 |
Epigenetic therapy of cancer with 5-aza-2'-deoxycytidine (decitabine). | Seminars in oncology 20051001 |
Innovative approaches to the clinical development of DNA methylation inhibitors as epigenetic remodeling drugs. | Seminars in oncology 20051001 |
Clinical development of decitabine as a prototype for an epigenetic drug program. | Seminars in oncology 20051001 |
Epigenetic treatment of hematopoietic malignancies: in vivo targets of demethylating agents. | Seminars in oncology 20051001 |
[Inhibitory effect of 5-Aza-2'-deoxycytidine on human nasopharyngeal carcinoma xenograft in nude mice]. | Ai zheng = Aizheng = Chinese journal of cancer 20051001 |
Down-regulation of DNA mismatch repair proteins in human and murine tumor spheroids: implications for multicellular resistance to alkylating agents. | Molecular cancer therapeutics 20051001 |
Antimitogenic and chemosensitizing effects of the methylation inhibitor zebularine in ovarian cancer. | Molecular cancer therapeutics 20051001 |
Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine. | Molecular cancer therapeutics 20051001 |
Epigenetic therapy with decitabine for myelodysplasia and leukemia. | Future oncology (London, England) 20051001 |
Prolonged transcriptional silencing and CpG methylation induced by siRNAs targeted to the HIV-1 promoter region. | Journal of RNAi and gene silencing : an international journal of RNA and gene targeting research 20051001 |
Mapping of the methylation pattern of the MUC2 promoter in pancreatic cancer cell lines, using bisulfite genomic sequencing. | Cancer letters 20050928 |
Epigenetic basis for the transcriptional hyporesponsiveness of the human inducible nitric oxide synthase gene in vascular endothelial cells. | Journal of immunology (Baltimore, Md. : 1950) 20050915 |
The retinoic acid synthesis gene ALDH1a2 is a candidate tumor suppressor in prostate cancer. | Cancer research 20050915 |
GADD45 deregulation in cancer: frequently methylated tumor suppressors and potential therapeutic targets. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050915 |
The stress-responsive gene GADD45G is a functional tumor suppressor, with its response to environmental stresses frequently disrupted epigenetically in multiple tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050915 |
Insensitivity to transforming growth factor-beta results from promoter methylation of cognate receptors in human prostate cancer cells (LNCaP). | Molecular endocrinology (Baltimore, Md.) 20050901 |
Genetic and epigenetic alterations of RB2/p130 tumor suppressor gene in human sporadic retinoblastoma: implications for pathogenesis and therapeutic approach. | Oncogene 20050901 |
Conditional expression of the CTCF-paralogous transcriptional factor BORIS in normal cells results in demethylation and derepression of MAGE-A1 and reactivation of other cancer-testis genes. | Cancer research 20050901 |
Strategies for biology- and molecular-based treatment of myelodysplastic syndromes. | Current drug targets 20050901 |
DNA methylation in the treatment of hematologic malignancies. | Clinical advances in hematology & oncology : H&O 20050901 |
CpG methylation of the PAI-1 gene 5'-flanking region is inversely correlated with PAI-1 mRNA levels in human cell lines. | Thrombosis and haemostasis 20050901 |
Hypermethylation of the RUNX3 gene in hepatocellular carcinoma. | Experimental & molecular medicine 20050831 |
Inactivation of monocarboxylate transporter MCT3 by DNA methylation in atherosclerosis. | Circulation 20050830 |
Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles. | British journal of cancer 20050822 |
Characterization of DNA demethylation effects induced by 5-Aza-2'-deoxycytidine in patients with myelodysplastic syndrome. | Cancer research 20050815 |
Cytochrome P450 1B1 is overexpressed and regulated by hypomethylation in prostate cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050815 |
P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050815 |
Clinicopathologic and prognostic values of apolipoprotein D alterations in hepatocellular carcinoma. | International journal of cancer 20050810 |
Granulocyte-macrophage colony-stimulating factor induces de novo methylation of the p15 CpG island in hematopoietic cells. | Cytokine 20050807 |
Myostatin inhibits myogenesis and promotes adipogenesis in C3H 10T(1/2) mesenchymal multipotent cells. | Endocrinology 20050801 |
Expression and methylation status of the FHIT gene in acute myeloid leukemia and myelodysplastic syndrome. | Leukemia 20050801 |
Genomic screens for genes upregulated by demethylation in colorectal cancer: possible usefulness for clinical application. | International journal of oncology 20050801 |
Azacitidine: a novel agent for myelodysplastic syndromes. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050801 |
Methylation-associated silencing of death-associated protein kinase gene in laryngeal squamous cell cancer. | The Laryngoscope 20050801 |
Advances in myelodysplastic syndrome: nursing implications of azacitidine. | Clinical journal of oncology nursing 20050801 |
Conventional and new treatment options for myelofibrosis with myeloid metaplasia. | Seminars in oncology 20050801 |
CTCF regulates growth and erythroid differentiation of human myeloid leukemia cells. | The Journal of biological chemistry 20050729 |
Silencing of the Tropomyosin-1 gene by DNA methylation alters tumor suppressor function of TGF-beta. | Oncogene 20050728 |
Promoter characterization of Semaphorin SEMA3F, a tumor suppressor gene. | Biochimica et biophysica acta 20050725 |
Release of methyl CpG binding proteins and histone deacetylase 1 from the Estrogen receptor alpha (ER) promoter upon reactivation in ER-negative human breast cancer cells. | Molecular endocrinology (Baltimore, Md.) 20050701 |
The expression of endothelial nitric-oxide synthase is controlled by a cell-specific histone code. | The Journal of biological chemistry 20050701 |
Metabolic activation of zebularine, a novel DNA methylation inhibitor, in human bladder carcinoma cells. | Biochemical pharmacology 20050701 |
DNA methylation disturbances as novel therapeutic target in lung cancer: preclinical and clinical results. | Critical reviews in oncology/hematology 20050701 |
KP-1212/1461, a nucleoside designed for the treatment of HIV by viral mutagenesis. | Antiviral research 20050701 |
CpG methylation at promoter site -140 inactivates TGFbeta2 receptor gene in prostate cancer. | Cancer 20050701 |
Resistance to Fas-mediated apoptosis is restored by cycloheximide through the downregulation of cellular FLIPL in NK/T-cell lymphoma. | Laboratory investigation; a journal of technical methods and pathology 20050701 |
Antileukemia activity of the combination of 5-aza-2'-deoxycytidine with valproic acid. | Leukemia research 20050701 |
Methylation of the MLH1 gene in hematological malignancies. | Oncology reports 20050701 |
The tissue-specific methylation of the human tyrosine hydroxylase gene reveals new regulatory elements in the first exon. | Journal of neurochemistry 20050701 |
Aberrant methylation of the Human Hedgehog interacting protein (HHIP) gene in pancreatic neoplasms. | Cancer biology & therapy 20050701 |
Epigenetic down-regulation of CDKN1C/p57KIP2 in pancreatic ductal neoplasms identified by gene expression profiling. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050701 |
Introduction: emerging role of epigenetic therapy: focus on decitabine. | Seminars in hematology 20050701 |
Decitabine dosing schedules. | Seminars in hematology 20050701 |
Decitabine in myelodysplastic syndromes. | Seminars in hematology 20050701 |
Decitabine in acute myeloid leukemia. | Seminars in hematology 20050701 |
Decitabine in chronic leukemias. | Seminars in hematology 20050701 |
Pharmacology of 5-Aza-2'-deoxycytidine (decitabine). | Seminars in hematology 20050701 |
Induction of HLA-G expression in a melanoma cell line OCM-1A following the treatment with 5-aza-2'-deoxycytidine. | Cell research 20050701 |
Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells. | The Journal of biological chemistry 20050617 |
Evaluation of a 7-day continuous intravenous infusion of decitabine: inhibition of promoter-specific and global genomic DNA methylation. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050610 |
TWIST2 demonstrates differential methylation in immunoglobulin variable heavy chain mutated and unmutated chronic lymphocytic leukemia. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050610 |
Pharmacokinetics of 5-azacitidine administered with phenylbutyrate in patients with refractory solid tumors or hematologic malignancies. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050610 |
Inactivation of the lamin A/C gene by CpG island promoter hypermethylation in hematologic malignancies, and its association with poor survival in nodal diffuse large B-cell lymphoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050610 |
Phase II study of low-dose decitabine in patients with chronic myelogenous leukemia resistant to imatinib mesylate. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050610 |
Reduced expression of chemokine (C-C motif) ligand-2 (CCL2) in ovarian adenocarcinoma. | British journal of cancer 20050606 |
Collagen alpha1(I) gene (COL1A1) is repressed by RFX family. | The Journal of biological chemistry 20050603 |
Genetic and epigenetic alterations of the candidate tumor-suppressor gene MYO18B, on chromosome arm 22q, in colorectal cancer. | Genes, chromosomes & cancer 20050601 |
DNA hypomethylation in 5-azacytidine-induced early-flowering lines of flax. | TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik 20050601 |
Distribution of the chromatin protein DEK distinguishes active and inactive CD21/CR2 gene in pre- and mature B lymphocytes. | International immunology 20050601 |
Chromatin remodeling in plant cell culture: patterns of DNA methylation and histone H3 and H4 acetylation vary during growth of asynchronous potato cell suspensions. | Plant physiology and biochemistry : PPB 20050601 |
Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation. | Cancer research 20050601 |
Methylation silencing of the Apaf-1 gene in acute leukemia. | Molecular cancer research : MCR 20050601 |
Contribution of epigenetic silencing of tumor necrosis factor-related apoptosis inducing ligand receptor 1 (DR4) to TRAIL resistance and ovarian cancer. | Molecular cancer research : MCR 20050601 |
Differentiation, engraftment and functional effects of pre-treated mesenchymal stem cells in a rat myocardial infarct model. | Acta cardiologica 20050601 |
Characterisation of human histone H1x. | Biological chemistry 20050601 |
Organization, not duplication, triggers silencing in a complex transgene locus in rice. | Plant molecular biology 20050601 |
5-Azacytidine suppresses RNA polymerase II recruitment to the SLPI gene. | Biochemical and biophysical research communications 20050527 |
CRD-BP/IMP1 expression characterizes cord blood CD34+ stem cells and affects c-myc and IGF-II expression in MCF-7 cancer cells. | The Journal of biological chemistry 20050520 |
Approval summary: azacitidine for treatment of myelodysplastic syndrome subtypes. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050515 |
5-Aza-2'-deoxycytidine induces p21WAF expression by demethylation of p73 leading to p53-independent apoptosis in myeloid leukemia. | International journal of cancer 20050501 |
Differential epigenetic modifications in the FMR1 gene of the fragile X syndrome after reactivating pharmacological treatments. | European journal of human genetics : EJHG 20050501 |
A two-edged role for the transposable element Kiddo in the rice ubiquitin2 promoter. | The Plant cell 20050501 |
Loss of caspase-1 gene expression in human gastric carcinomas and cell lines. | International journal of oncology 20050501 |
Bioavailability of azacitidine subcutaneous versus intravenous in patients with the myelodysplastic syndromes. | Journal of clinical pharmacology 20050501 |
New agents in myelodysplastic syndromes. | Current hematology reports 20050501 |
RASSF1A suppresses the c-Jun-NH2-kinase pathway and inhibits cell cycle progression. | Cancer research 20050501 |
Azacitidine-induced interstitial and alveolar fibrosis in a patient with myelodysplastic syndrome. | Pharmacotherapy 20050501 |
The controversial denouement of vertebrate DNA methylation research. | Biochemistry. Biokhimiia 20050501 |
Azacitidine. | Nature reviews. Drug discovery 20050501 |
Stimulation of P19CL6 with multiple reagents induces pulsating particles in vivo. | Current medical research and opinion 20050501 |
Methylation of CpG islands in the rat 7-dehydrocholesterol reductase promoter suppresses transcriptional activation. | Molecules and cells 20050430 |
De novo DNA methyltransferases Dnmt3a and Dnmt3b primarily mediate the cytotoxic effect of 5-aza-2'-deoxycytidine. | Oncogene 20050428 |
Altered expression of topoisomerase IIalpha contributes to cross-resistant to etoposide K562/MX2 cell line by aberrant methylation. | British journal of cancer 20050425 |
Epigenetic alteration at the DLK1-GTL2 imprinted domain in human neoplasia: analysis of neuroblastoma, phaeochromocytoma and Wilms' tumour. | British journal of cancer 20050425 |
Role of histone deacetylation in cell-specific expression of endothelial nitric-oxide synthase. | The Journal of biological chemistry 20050422 |
Frequent silencing of DBC1 is by genetic or epigenetic mechanisms in non-small cell lung cancers. | Human molecular genetics 20050415 |
Co-culture of human CD34+ cells with mesenchymal stem cells increases the survival of CD34+ cells against the 5-aza-deoxycytidine- or trichostatin A-induced cell death. | Biochemical and biophysical research communications 20050415 |
Analysis of methylation-sensitive transcriptome identifies GADD45a as a frequently methylated gene in breast cancer. | Oncogene 20050414 |
Methylation and acetylation characteristics of cloned bovine embryos from donor cells treated with 5-aza-2'-deoxycytidine. | Biology of reproduction 20050401 |
Hypermethylation of the promoter region is associated with the loss of MEG3 gene expression in human pituitary tumors. | The Journal of clinical endocrinology and metabolism 20050401 |
Epigenetic and genetic alterations of p33ING1b in ovarian cancer. | Carcinogenesis 20050401 |
An intron GATA-binding site regulates chromatin accessibility and is essential for IL-4 gene expression in mast cells. | European journal of immunology 20050401 |
Activation of p53/p21Waf1/Cip1 pathway by 5-aza-2'-deoxycytidine inhibits cell proliferation, induces pro-apoptotic genes and mitogen-activated protein kinases in human prostate cancer cells. | International journal of oncology 20050401 |
Methylthioadenosine phosphorylase gene is silenced by promoter hypermethylation in human lymphoma cell line DHL-9: another mechanism of enzyme deficiency. | International journal of oncology 20050401 |
Methylation of the CA9 promoter can modulate expression of the tumor-associated carbonic anhydrase IX in dense carcinoma cell lines. | International journal of oncology 20050401 |
Status of reduced expression and hypermethylation of the APC tumor suppressor gene in human oral squamous cell carcinoma. | International journal of molecular medicine 20050401 |
Adult murine skeletal muscle contains cells that can differentiate into beating cardiomyocytes in vitro. | PLoS biology 20050401 |
Effect of 5-azacytidine and procainamide on CD3-zeta chain expression in Jurkat T cells. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20050401 |
Histone deacetylase inhibitors decrease DNA methyltransferase-3B messenger RNA stability and down-regulate de novo DNA methyltransferase activity in human endometrial cells. | Cancer research 20050401 |
Reversible conversion of immortal human cells from telomerase-positive to telomerase-negative cells. | Cancer research 20050401 |
Alchemy and the new age of cardiac muscle cell biology. | PLoS biology 20050401 |
[Analysis of the methylation in the promoter of LRP15 gene and its expression]. | Zhongguo shi yan xue ye xue za zhi 20050401 |
Azacitidine. | Nature reviews. Drug discovery 20050401 |
Aberrant CpG island hypermethylation profile is associated with atypical and anaplastic meningiomas. | Human pathology 20050401 |
Sequential 5-Aza 2'-deoxycytidine/depsipeptide FK228 treatment induces tissue factor pathway inhibitor 2 (TFPI-2) expression in cancer cells. | Oncogene 20050331 |
Aberrant promoter methylation in human DAB2 interactive protein (hDAB2IP) gene in gastrointestinal tumour. | British journal of cancer 20050328 |
Discovery of aberrant expression of R-RAS by cancer-linked DNA hypomethylation in gastric cancer using microarrays. | Cancer research 20050315 |
Retinoic acid targets DNA-methyltransferases and histone deacetylases during APL blast differentiation in vitro and in vivo. | Oncogene 20050310 |
Regulation of replication at the R/G chromosomal band boundary and pericentromeric heterochromatin of mammalian cells. | Experimental cell research 20050310 |
Cytokine preconditioning promotes codifferentiation of human fetal liver CD133+ stem cells into angiomyogenic tissue. | Circulation 20050308 |
Downregulation of 14-3-3sigma in ovary, prostate and endometrial carcinomas is associated with CpG island methylation. | Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20050301 |
Cell type-specific regulation of the TGF-beta-responsive alpha2(I) collagen gene by CpG methylation. | Journal of cellular physiology 20050301 |
Expression of aquaporin-5 in and fluid secretion from immortalized human salivary gland ductal cells by treatment with 5-aza-2'-deoxycytidine: a possibility for improvement of xerostomia in patients with Sjögren's syndrome. | Laboratory investigation; a journal of technical methods and pathology 20050301 |
Enhancement of antineoplastic action of 5-aza-2'-deoxycytidine by zebularine on L1210 leukemia. | Anti-cancer drugs 20050301 |
Aberrant methylation of Reprimo in lung cancer. | Lung cancer (Amsterdam, Netherlands) 20050301 |
Epigenetic up-regulation of C-C chemokine receptor 7 and C-X-C chemokine receptor 4 expression in melanoma cells. | Cancer research 20050301 |
Potent selection of antigen loss variants of B16 melanoma following inflammatory killing of melanocytes in vivo. | Cancer research 20050301 |
Valproic acid, in combination with all-trans retinoic acid and 5-aza-2'-deoxycytidine, restores expression of silenced RARbeta2 in breast cancer cells. | Molecular cancer therapeutics 20050301 |
FDA drug approval summary: azacitidine (5-azacytidine, Vidaza) for injectable suspension. | The oncologist 20050301 |
Epigenetic silencing of the protocadherin family member PCDH-gamma-A11 in astrocytomas. | Neoplasia (New York, N.Y.) 20050301 |
The essential role of histone H3 Lys9 di-methylation and MeCP2 binding in MGMT silencing with poor DNA methylation of the promoter CpG island. | Journal of biochemistry 20050301 |
Structural and functional preservation of specific sequences of DNA and mRNA in apoptotic bodies from ES cells. | Apoptosis : an international journal on programmed cell death 20050301 |
[5-Aza-2'-deoxycytidine enhances differentiation and apoptosis induced by phenylbutyrate in Kasumi-1 cells]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20050301 |
Therapeutic epigenetics: an emerging clinical approach to hematologic malignancies. | Clinical advances in hematology & oncology : H&O 20050301 |
Hypermethylation of the 5' CpG island of the gene encoding the serine protease Testisin promotes its loss in testicular tumorigenesis. | British journal of cancer 20050227 |
Reactivation of SYK expression by inhibition of DNA methylation suppresses breast cancer cell invasiveness. | International journal of cancer 20050210 |
Aberrant methylation of HIN-1 (high in normal-1) is a frequent event in many human malignancies. | International journal of cancer 20050210 |
In vivo haematopoietic activity is induced in neurosphere cells by chromatin-modifying agents. | The EMBO journal 20050209 |
Differential properties of dentate gyrus and CA1 neural precursors. | Journal of neurobiology 20050205 |
Methylation-regulated expression of cancer testis antigens in primary effusion lymphoma: immunotherapeutic implications. | Journal of cellular physiology 20050201 |
Oncogene regulation of tumor suppressor genes in tumorigenesis. | Carcinogenesis 20050201 |
Demethylation using the epigenetic modifier, 5-azacytidine, increases the efficiency of transient transfection of macrophages. | Journal of lipid research 20050201 |
Silencing of the maternally imprinted tumor suppressor ARHI contributes to follicular thyroid carcinogenesis. | The Journal of clinical endocrinology and metabolism 20050201 |
5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms. | The Journal of pharmacology and experimental therapeutics 20050201 |
Quasispecies dynamics and RNA virus extinction. | Virus research 20050201 |
Action of mutagenic agents and antiviral inhibitors on foot-and-mouth disease virus. | Virus research 20050201 |
Reversing the silencing of reporter sodium/iodide symporter transgene for stem cell tracking. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20050201 |
[Experimental study of differentiation of mouse bone marrow stromal stem cells into progenitor cardiomyocyte in vitro]. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050201 |
Aberrant methylation and silencing of the BNIP3 gene in colorectal and gastric cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050201 |
Increased heparanase expression is caused by promoter hypomethylation and up-regulation of transcriptional factor early growth response-1 in human prostate cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050201 |
Silencing of the thrombomodulin gene in human malignant melanoma. | Melanoma research 20050201 |
Activation of CMV promoter-controlled glycosyltransferase and beta -galactosidase glycogenes by butyrate, tricostatin A, and 5-aza-2'-deoxycytidine. | Glycoconjugate journal 20050201 |
[Differentiation of mesenchymal stem cells into cardio myogenic cells under the induction of myocardial cell lysate]. | Zhonghua xin xue guan bing za zhi 20050201 |
MDS: practical treatment approaches for physicians and nurses. | Clinical advances in hematology & oncology : H&O 20050201 |
Azacitine (vidaza) for myelodysplastic syndrome. | The Medical letter on drugs and therapeutics 20050131 |
Epigenetic inactivation of TFPI-2 as a common mechanism associated with growth and invasion of pancreatic ductal adenocarcinoma. | Oncogene 20050127 |
Restoration of expression of transforming growth factor-beta type II receptor in murine renal cell carcinoma (renca) cells by 5-Aza-2'-deoxycytidine. | Life sciences 20050121 |
Silencing of the retinoid response gene TIG1 by promoter hypermethylation in nasopharyngeal carcinoma. | International journal of cancer 20050120 |
Characterization of {gamma}-aminobutyric acid type A receptor-associated protein, a novel tumor suppressor, showing reduced expression in breast cancer. | Cancer research 20050115 |
Methylation of the gamma-catenin gene is associated with poor prognosis of renal cell carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050115 |
Growth delay of human pancreatic cancer cells by methylase inhibitor 5-aza-2'-deoxycytidine treatment is associated with activation of the interferon signalling pathway. | Oncogene 20050106 |
Downregulation of connexin 26 in human lung cancer is related to promoter methylation. | International journal of cancer 20050101 |
Induction of gene expression by 5-Aza-2'-deoxycytidine in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) but not epithelial cells by DNA-methylation-dependent and -independent mechanisms. | Leukemia 20050101 |
Methylation analysis of the adenomatous polyposis coli (APC) gene in adult T-cell leukemia/lymphoma. | Leukemia research 20050101 |
DNA methylation and cancer therapy: new developments and expectations. | Current opinion in oncology 20050101 |
Morphological, electrophysiological and coupling characteristics of bone marrow-derived mononuclear cells-an in vitro-model. | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20050101 |
Human retinoblastoma cells are resistant to apoptosis induced by death receptors: role of caspase-8 gene silencing. | Investigative ophthalmology & visual science 20050101 |
Epigenetic regulation of O6-methylguanine-DNA methyltransferase gene expression by histone acetylation and methyl-CpG binding proteins. | Molecular cancer therapeutics 20050101 |
Formation of embryogenic cell clumps from carrot epidermal cells is suppressed by 5-azacytidine, a DNA methylation inhibitor. | Journal of plant physiology 20050101 |
[Experimental study on the myogenic differentiation of marrow mesenchymal stem cells in the local muscle tissues]. | Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20050101 |
Epigenetic silencing of cellular retinol-binding proteins in nasopharyngeal carcinoma. | Neoplasia (New York, N.Y.) 20050101 |
Differentiation 'in vitro' of primary and immortalized porcine mesenchymal stem cells into cardiomyocytes for cell transplantation. | Transplantation proceedings 20050101 |
Abrogation of DUSP6 by hypermethylation in human pancreatic cancer. | Journal of human genetics 20050101 |
A phase I study of hydralazine to demethylate and reactivate the expression of tumor suppressor genes. | BMC cancer 20050101 |
Inhibition of chromatin condensation prevents transgene silencing in a neural progenitor cell line transplanted to the rat brain. | Cell transplantation 20050101 |
A transcriptome map of cellular transformation by the fos oncogene. | Molecular cancer 20050101 |
CpG-island fragments from the HNRPA2B1/CBX3 genomic locus reduce silencing and enhance transgene expression from the hCMV promoter/enhancer in mammalian cells. | BMC biotechnology 20050101 |
Azacitidine: in myelodysplastic syndromes. | Drugs 20050101 |
X-inactivation status varies in human embryonic stem cell lines. | Stem cells (Dayton, Ohio) 20050101 |
Epigenetic inactivation and aberrant transcription of CSMD1 in squamous cell carcinoma cell lines. | Cancer cell international 20050101 |
Epigenetic predisposition to expression of TIMP1 from the human inactive X chromosome. | BMC genetics 20050101 |
Rumex acetosa Y chromosomes: constitutive or facultative heterochromatin? | Folia histochemica et cytobiologica 20050101 |
Histone deacetylation is directly involved in desilencing the expression of the catalytic subunit of telomerase in normal lung fibroblast. | Journal of cellular and molecular medicine 20050101 |
Epigenetics of cervical cancer. An overview and therapeutic perspectives. | Molecular cancer 20050101 |
Update on supportive care and new therapies: immunomodulatory drugs, growth factors and epigenetic-acting agents. | Hematology. American Society of Hematology. Education Program 20050101 |
Lack of cardiac differentiation in c-kit-enriched porcine bone marrow and spleen hematopoietic cell cultures using 5-azacytidine. | Cells, tissues, organs 20050101 |
Pharmacological induction of fetal hemoglobin: Why haven't we been more successful in thalassemia? | Annals of the New York Academy of Sciences 20050101 |
Transformation of revertant murine cells by 5-azacytidine results in rapid inhibition of lysyl oxidase expression. | Acta microbiologica et immunologica Hungarica 20050101 |
5-azacytidine induces cardiac differentiation of P19 embryonic stem cells. | Experimental & molecular medicine 20041231 |
Quantification of 5-azacytidine in plasma by electrospray tandem mass spectrometry coupled with high-performance liquid chromatography. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225 |
Establishment of a detection system for demethylating agents using an endogenous promoter CpG island. | Mutation research 20041221 |
Inactivation of the hMSH3 mismatch repair gene in bladder cancer. | Biochemical and biophysical research communications 20041217 |
Intratumor heterogeneity of cancer/testis antigens expression in human cutaneous melanoma is methylation-regulated and functionally reverted by 5-aza-2'-deoxycytidine. | Cancer research 20041215 |
Regulation of Chk2 gene expression in lymphoid malignancies: involvement of epigenetic mechanisms in Hodgkin's lymphoma cell lines. | Cell death and differentiation 20041201 |
Genome-wide demethylation destabilizes CTG.CAG trinucleotide repeats in mammalian cells. | Human molecular genetics 20041201 |
Nonclonal neutrophil responses after successful treatment of myelodysplasia with low-dose 5-aza-2'-deoxycytidine (decitabine). | Leukemia research 20041201 |
DNA methyltransferase inhibitors in myelodysplastic syndrome. | Best practice & research. Clinical haematology 20041201 |
Histone deacetylase inhibitors in myelodysplastic syndrome. | Best practice & research. Clinical haematology 20041201 |
Zebularine: a new drug for epigenetic therapy. | Biochemical Society transactions 20041201 |
DNA methylation affects cell proliferation, cortisol secretion and steroidogenic gene expression in human adrenocortical NCI-H295R cells. | Journal of molecular endocrinology 20041201 |
Decitabine. MGI Pharma Inc/SuperGen Inc. | IDrugs : the investigational drugs journal 20041201 |
Hypermethylation of the death-associated protein kinase promoter attenuates the sensitivity to TRAIL-induced apoptosis in human non-small cell lung cancer cells. | Molecular cancer research : MCR 20041201 |
Caspase-8 gene expression in neuroblastoma. | Annals of the New York Academy of Sciences 20041201 |
Epigenetic regulation of protein phosphatase 2A (PP2A), lymphotactin (XCL1) and estrogen receptor alpha (ER) expression in human breast cancer cells. | Cancer biology & therapy 20041201 |
Translational research in myelodysplastic syndromes. | Reviews in clinical and experimental hematology 20041201 |
Expression and regulation of MIM (Missing In Metastasis), a novel putative metastasis suppressor gene, and MIM-B, in bladder cancer cell lines. | Cancer letters 20041125 |
Silencing the critics: new studies move closer to answering epigenetic questions. | Journal of the National Cancer Institute 20041117 |
Epigenetic silencing of the immunoglobulin heavy-chain gene in classical Hodgkin lymphoma-derived cell lines contributes to the loss of immunoglobulin expression. | Blood 20041115 |
Investigation of the role of SDHB inactivation in sporadic phaeochromocytoma and neuroblastoma. | British journal of cancer 20041115 |
Epigenetic inactivation of ID4 in colorectal carcinomas correlates with poor differentiation and unfavorable prognosis. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041115 |
Ex vivo differentiation of human adult bone marrow stem cells into cardiomyocyte-like cells. | Biochemical and biophysical research communications 20041112 |
Loss of maspin expression is associated with development and progression of gastric carcinoma with p53 abnormality. | Oncology reports 20041101 |
Epigenetic silencing of E- and P-cadherin gene expression in human melanoma cell lines. | International journal of oncology 20041101 |
5-Azacytidine supports the long-term repopulating activity of cord blood CD34(+) cells. | American journal of hematology 20041101 |
Hypermethylation of growth arrest DNA damage-inducible gene 45 beta promoter in human hepatocellular carcinoma. | The American journal of pathology 20041101 |
Effects of DNA methylation inhibitor on down-regulation of ribonuclease inhibitor expression in cancer cell lines. | Ai zheng = Aizheng = Chinese journal of cancer 20041101 |
[Research on the growth inhibition of T47D cell and reversion of p16 hypermethylation by CDP]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20041101 |
Identification of a genomic fragment that directs hematopoietic-specific expression of Rac2 and analysis of the DNA methylation profile of the gene locus. | Gene 20041027 |
Reduced expression of MYO18B, a candidate tumor-suppressor gene on chromosome arm 22q, in ovarian cancer. | International journal of cancer 20041020 |
Sp17 gene expression in myeloma cells is regulated by promoter methylation. | British journal of cancer 20041018 |
Epigenetic regulation of 11 beta-hydroxysteroid dehydrogenase type 2 expression. | The Journal of clinical investigation 20041015 |
The in vitro and in vivo effects of re-expressing methylated von Hippel-Lindau tumor suppressor gene in clear cell renal carcinoma with 5-aza-2'-deoxycytidine. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041015 |
Aberrant methylation of DPYD promoter, DPYD expression, and cellular sensitivity to 5-fluorouracil in cancer cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041015 |
Identification of an epigenetically silenced gene, RFX1, in human glioma cells using restriction landmark genomic scanning. | Oncogene 20041014 |
Demethylating agent, 5-azacytidine, reverses differentiation of embryonic stem cells. | Biochemical and biophysical research communications 20041008 |
Establishment and characterisation of a human carcinoma cell line with acquired resistance to Aplidin. | British journal of cancer 20041004 |
Microarray analysis of gene regulation in the Hepa1c1c7 cell line following exposure to the DNA methylation inhibitor 5-aza-2'-deoxycytidine and 2,3,7,8-tetrachlorodibenzo-p-dioxin. | Toxicology in vitro : an international journal published in association with BIBRA 20041001 |
Maternal chromatin remodeling during maturation and after fertilization in mouse oocytes. | Molecular reproduction and development 20041001 |
Aberrant methylation of RASSF4/AD037 in nasopharyngeal carcinoma. | Oncology reports 20041001 |
Sp1-mediated transcriptional control of fibroblast growth factor receptor 4 in sarcomas of skeletal muscle lineage. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041001 |
Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach. | Cancer cell 20041001 |
[Methylation of mismatch repair gene (MMR) in primary hepatocellular carcinoma]. | Zhonghua bing li xue za zhi = Chinese journal of pathology 20041001 |
Clinical studies with fetal hemoglobin-enhancing agents in sickle cell disease. | Seminars in hematology 20041001 |
The role of fetal hemoglobin-enhancing agents in thalassemia. | Seminars in hematology 20041001 |
Issues regarding study design for initial clinical trials using decitabine. | Seminars in hematology 20041001 |
Clinical and oncologic implications in epigenetic down-regulation of CD26/dipeptidyl peptidase IV in adult T-cell leukemia cells. | International journal of hematology 20041001 |
5-aza-2'-deoxycytidine upregulates caspase-9 expression cooperating with p53-induced apoptosis in human lung cancer cells. | Oncogene 20040902 |
Folic acid-mediated inhibition of serum-induced activation of EGFR promoter in colon cancer cells. | American journal of physiology. Gastrointestinal and liver physiology 20040901 |
Changes in DNA methylation during somatic embryogenesis in Cucurbita pepo L. | Plant cell reports 20040901 |
Effect of paternal tamoxifen on the expression of insulin-like growth factor 2 and insulin-like growth factor type 1 receptor in the post-implantation rat embryos. | Molecular reproduction and development 20040901 |
Demethylating agent 5-aza-2'-deoxycytidine enhances expression of TNFRI and promotes TNF-mediated apoptosis in vitro and in vivo. | Oncology reports 20040901 |
Enhanced sensitivity of prostate cancer DU145 cells to cisplatinum by 5-aza-2'-deoxycytidine. | Oncology reports 20040901 |
Prevalent hyper-methylation of the CDH13 gene promoter in malignant B cell lymphomas. | International journal of oncology 20040901 |
DNA hypo-methylating agents and sickle cell disease. | British journal of haematology 20040901 |
CpG hypermethylation of MDR1 gene contributes to the pathogenesis and progression of human prostate cancer. | Cancer research 20040901 |
Favorable neuroblastoma genes and molecular therapeutics of neuroblastoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040901 |
Methylation-associated silencing of the Wnt antagonist SFRP1 gene in human ovarian cancers. | Cancer science 20040901 |
DNA hypomethylation induced by non-genotoxic carcinogens in mouse and rat colon. | Cancer letters 20040830 |
S100A6 (Calcyclin) is a prostate basal cell marker absent in prostate cancer and its precursors. | British journal of cancer 20040816 |
The cell-specific expression of endothelial nitric-oxide synthase: a role for DNA methylation. | The Journal of biological chemistry 20040813 |
Expression of the human myotonic dystrophy kinase-related Cdc42-binding kinase gamma is regulated by promoter DNA methylation and Sp1 binding. | The Journal of biological chemistry 20040813 |
The frequent expression of cancer/testis antigens provides opportunities for immunotherapeutic targeting of sarcoma. | Cancer immunity 20040809 |
Promoter hypermethylation silences cyclooxygenase-2 (Cox-2) and regulates growth of human hepatocellular carcinoma cells. | Laboratory investigation; a journal of technical methods and pathology 20040801 |
Myelodysplasia, megakaryocytes, and methylation. | Leukemia research 20040801 |
The effects of 5-aza-2'-deoxycytidine (Decitabine) on the platelet count in patients with intermediate and high-risk myelodysplastic syndromes. | Leukemia research 20040801 |
Demethylation of DNA by decitabine in cancer chemotherapy. | Expert review of anticancer therapy 20040801 |
Apoptotic speck protein-like, a highly homologous protein to apoptotic speck protein in the pyrin domain, is silenced by DNA methylation and induces apoptosis in human hepatocellular carcinoma. | Cancer research 20040801 |
Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer. | Cancer research 20040801 |
[Effect of 5-aza-2'-deoxycytidine on cell of high-risk patients with myelodysplastic syndrome in vitro]. | Zhongguo shi yan xue ye xue za zhi 20040801 |
DNA methylation as a therapeutic target in hematologic disorders: recent results in older patients with myelodysplasia and acute myeloid leukemia. | International journal of hematology 20040801 |
[Growth and gene expression of leukemia cell after treated with methylation inhibitor 5-aza-2'-deoxycytidine]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20040801 |
Role of the putative tumor metastasis suppressor gene Drg-1 in breast cancer progression. | Oncogene 20040722 |
Reduced expression of small GTPases and hypermethylation of the folate binding protein gene in cisplatin-resistant cells. | British journal of cancer 20040719 |
HER-2, gp100, and MAGE-1 are expressed in human glioblastoma and recognized by cytotoxic T cells. | Cancer research 20040715 |
Methylation in the core-promoter region of the chondromodulin-I gene determines the cell-specific expression by regulating the binding of transcriptional activator Sp3. | The Journal of biological chemistry 20040702 |
Effects of demethylating agent 5-aza-2(')-deoxycytidine and histone deacetylase inhibitor FR901228 on maspin gene expression in oral cancer cell lines. | Oral oncology 20040701 |
MEIS 1 expression is downregulated through promoter hypermethylation in AML1-ETO acute myeloid leukemias. | Leukemia 20040701 |
Less frequent promoter hypermethylation of DLC-1 gene in primary breast cancers. | Oncology reports 20040701 |
Autologous transplantation of bone marrow mononuclear cells improved heart function after myocardial infarction. | Acta pharmacologica Sinica 20040701 |
Mesenchymal stem cells from adult human bone marrow differentiate into a cardiomyocyte phenotype in vitro. | Experimental biology and medicine (Maywood, N.J.) 20040701 |
Loss of disialyl Lewis(a), the ligand for lymphocyte inhibitory receptor sialic acid-binding immunoglobulin-like lectin-7 (Siglec-7) associated with increased sialyl Lewis(a) expression on human colon cancers. | Cancer research 20040701 |
Methylation-associated silencing of the heat shock protein 47 gene in human neuroblastoma. | Cancer research 20040701 |
Retrovirus silencing, variegation, extinction, and memory are controlled by a dynamic interplay of multiple epigenetic modifications. | Molecular therapy : the journal of the American Society of Gene Therapy 20040701 |
Aberrant gene expression in human non small cell lung carcinoma cells exposed to demethylating agent 5-aza-2'-deoxycytidine. | Neoplasia (New York, N.Y.) 20040701 |
[Epiplastome variation of the number of chloroplasts in stomata guard cells of sugar beet (Beta vulgaris L.)]. | Genetika 20040701 |
Molecular mechanisms regulating cell type specific expression of BMP/RA Inducible Neural-specific Protein-1 that suppresses cell cycle progression: roles of NRSF/REST and DNA methylation. | Brain research. Molecular brain research 20040618 |
SOCS1 and SHP1 hypermethylation in multiple myeloma: implications for epigenetic activation of the Jak/STAT pathway. | Blood 20040615 |
Epigenetic modifications affect Dnmt3L expression. | The Biochemical journal 20040615 |
Membrane transporters and channels: role of the transportome in cancer chemosensitivity and chemoresistance. | Cancer research 20040615 |
The candidate tumor suppressor gene BLU, located at the commonly deleted region 3p21.3, is an E2F-regulated, stress-responsive gene and inactivated by both epigenetic and genetic mechanisms in nasopharyngeal carcinoma. | Oncogene 20040610 |
Progesterone receptor gene inactivation and CpG island hypermethylation in human leukemia cancer cells. | FEBS letters 20040604 |
Modification of hematopoietic stem cell fate by 5aza 2'deoxycytidine and trichostatin A. | Blood 20040601 |
MDR1 promoter hypermethylation in MCF-7 human breast cancer cells: changes in chromatin structure induced by treatment with 5-Aza-cytidine. | Cancer biology & therapy 20040601 |
Promoter methylation and protein expression of the E-cadherin gene in the clinicopathologic assessment of adenoid cystic carcinoma. | Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20040601 |
Activation of a rice endogenous retrotransposon Tos17 in tissue culture is accompanied by cytosine demethylation and causes heritable alteration in methylation pattern of flanking genomic regions. | TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik 20040601 |
Antineoplastic action of 5-aza-2'-deoxycytidine (Dacogen) and depsipeptide on Raji lymphoma cells. | Oncology reports 20040601 |
Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma. | Cancer research 20040601 |
Krüppel-like factor 6 is frequently down-regulated and induces apoptosis in non-small cell lung cancer cells. | Cancer research 20040601 |
The IL-12Rbeta2 gene functions as a tumor suppressor in human B cell malignancies. | The Journal of clinical investigation 20040601 |
Overexpression of CD70 and overstimulation of IgG synthesis by lupus T cells and T cells treated with DNA methylation inhibitors. | Arthritis and rheumatism 20040601 |
Pharmacological induction of fetal hemoglobin synthesis using histone deacetylase inhibitors. | Hematology (Amsterdam, Netherlands) 20040601 |
Epigenetic modification regulates both expression of tumor-associated genes and cell cycle progressing in human colon cancer cell lines: Colo-320 and SW1116. | Cell research 20040601 |
Epigenetic regulation of MDR1 gene in breast cancer: CpG methylation status dominates the stable maintenance of a silent gene. | Cancer biology & therapy 20040601 |
5-azacytidine alters TGF-beta and BMP signaling and induces maturation in articular chondrocytes. | Journal of cellular biochemistry 20040515 |
RASSF1A is a target tumor suppressor from 3p21.3 in nasopharyngeal carcinoma. | International journal of cancer 20040510 |
Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling. | Carcinogenesis 20040501 |
The value of DNA methylation analysis in basic, initial toxicity assessments. | Toxicological sciences : an official journal of the Society of Toxicology 20040501 |
DNA methylation profiles of lymphoid and hematopoietic malignancies. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040501 |
Gamma-catenin expression is reduced or absent in a subset of human non-small cell lung cancers, and its re-expression inhibits cell growth. | Chest 20040501 |
The epigenetic stability of the locus control region-deficient IgH locus in mouse hybridoma cells is a clonally varying, heritable feature. | Genetics 20040501 |
Cardiac muscle plasticity in adult and embryo by heart-derived progenitor cells. | Annals of the New York Academy of Sciences 20040501 |
Hypermethylation of the PTEN gene in ovarian cancer cell lines. | Cancer letters 20040430 |
Epigenetic control of mouse Oct-4 gene expression in embryonic stem cells and trophoblast stem cells. | The Journal of biological chemistry 20040423 |
Cancer chemotherapy targeted at reactivating the expression of epigenetically inactivated genes. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040415 |
Azacitidine induces demethylation of the Epstein-Barr virus genome in tumors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040415 |
Promoter methylation inhibits APC gene expression by causing changes in chromatin conformation and interfering with the binding of transcription factor CCAAT-binding factor. | Cancer research 20040415 |
Frequent alterations of Ras signaling pathway genes in sporadic malignant melanomas. | International journal of cancer 20040410 |
5-aza-2'-deoxycytidine activates the p53/p21Waf1/Cip1 pathway to inhibit cell proliferation. | The Journal of biological chemistry 20040409 |
Human PinX1, a potent telomerase inhibitor, is not involved in human gastrointestinal tract carcinoma. | Oncology reports 20040401 |
Hypermethylation and silencing of the putative tumor suppressor Tazarotene-induced gene 1 in human cancers. | Cancer research 20040401 |
Effect of 5-azacytidine and trichostatin A on somatic centromere association in wheat. | Genome 20040401 |
Demethylation of the synuclein gamma gene CpG island in primary gastric cancers and gastric cancer cell lines. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040401 |
The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040401 |
Targeted therapies in myelodysplastic syndromes: ASH 2003 review. | Seminars in hematology 20040401 |
[Cardiomyocyte-like differentiation of human bone marrow mesenchymal stem cells after exposure of 5-azacytidine in vitro]. | Shi yan sheng wu xue bao 20040401 |
Promoter methylation regulates cadherin switching in squamous cell carcinoma. | Biochemical and biophysical research communications 20040319 |
Hypermethylation and transcriptional downregulation of the carboxyl-terminal modulator protein gene in glioblastomas. | Journal of the National Cancer Institute 20040317 |
Hypermethylation of the 5' CpG island of the FHIT gene is associated with hyperdiploid and translocation-negative subtypes of pediatric leukemia. | Cancer research 20040315 |
Plakoglobin is a new target gene of histone deacetylase in human fibrosarcoma HT1080 cells. | Oncogene 20040304 |
Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies. | Blood 20040301 |
Hypermethylation of retrotransposons in the liverwort Marchantia paleacea var. diptera. | Plant cell reports 20040301 |
Frequent hypermethylation of 5' flanking region of TIMP-2 gene in cervical cancer. | International journal of cancer 20040301 |
Reduced selenium-binding protein 1 expression is associated with poor outcome in lung adenocarcinomas. | The Journal of pathology 20040301 |
DNA methylation as an epigenetic regulator of neural 5-lipoxygenase expression: evidence in human NT2 and NT2-N cells. | Journal of neurochemistry 20040301 |
Genomic surgery for lung cancer. | The Journal of surgical research 20040301 |
Transplacental exposure to the DNA demethylating agent, 5-AZA-CdR, affects the sexual behavior of CD-1 male mice. | Neurotoxicology 20040301 |
[Differentiation of rabbit bone marrow mesenchymal stem cells into myogenic cells in vitro and expression of vascular endothelial growth factor gene after transfection]. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20040301 |
Aberrant expression of the maspin gene associated with epigenetic modification in melanoma cells. | The Journal of investigative dermatology 20040301 |
Methylation of a CpG island within the uroplakin Ib promoter: a possible mechanism for loss of uroplakin Ib expression in bladder carcinoma. | Neoplasia (New York, N.Y.) 20040301 |
5-Aza-2'-deoxycytidine stimulates inducible nitric oxide synthase induction in C6 astrocytoma cells. | Brain research 20040213 |
Spontaneous cardiomyocyte differentiation from adipose tissue stroma cells. | Circulation research 20040206 |
5-Aza-2'-deoxycytidine and paclitaxel inhibit inducible nitric oxide synthase activation in fibrosarcoma cells. | European journal of pharmacology 20040206 |
Disruption of cell-type-specific methylation at the Maspin gene promoter is frequently involved in undifferentiated thyroid cancers. | Oncogene 20040205 |
Changes in methylation pattern of NMDA receptor NR2B gene in cortical neurons after chronic ethanol treatment in mice. | Brain research. Molecular brain research 20040205 |
Mutagenicity of the cytidine analog zebularine in Escherichia coli. | DNA repair 20040203 |
CpG methylation and transcription factors Sp1 and Sp3 regulate the expression of the human secretin receptor gene. | Molecular endocrinology (Baltimore, Md.) 20040201 |
Inhibitory effect of methylation inhibitor 5-aza-2-deoxycytidine on bile duct cancer cell line in vivo and in vitro. | Hepatobiliary & pancreatic diseases international : HBPD INT 20040201 |
[Effect of inhibitors for demethylation and histone deacetylase on proliferation of cell line K562 and expression of tumor related genes]. | Zhongguo shi yan xue ye xue za zhi 20040201 |
Developing a genetic system in Deinococcus radiodurans for analyzing mutations. | Genetics 20040201 |
Evaluation of antineoplastic action of 5-aza-2'-deoxycytidine (Dacogen) and docetaxel (Taxotere) on human breast, lung and prostate carcinoma cell lines. | Anti-cancer drugs 20040201 |
The absence of p53 is critical for the induction of apoptosis by 5-aza-2'-deoxycytidine. | Oncogene 20040122 |
Expression and regulation of tumor suppressor gene maspin in human bladder cancer. | Cancer letters 20040120 |
Differentiation of skeletal muscle from pituitary folliculo-stellate cells and endocrine progenitor cells. | Experimental cell research 20040115 |
Silencing of transgene transcription precedes methylation of promoter DNA and histone H3 lysine 9. | The EMBO journal 20040114 |
In vitro efficacy of combined treatment depends on the underlying mechanism of resistance in imatinib-resistant Bcr-Abl-positive cell lines. | Blood 20040101 |
Expression of the p16INK4a gene and methylation pattern of CpG sites in the promoter region in rat tumor cell lines. | Molecular carcinogenesis 20040101 |
CHFR-associated early G2/M checkpoint defects in breast cancer cells. | Molecular carcinogenesis 20040101 |
Limited gene activation in tumor and normal epithelial cells treated with the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine. | Molecular pharmacology 20040101 |
Granulocyte colony-stimulating factor generates epigenetic and genetic alterations in lymphocytes of normal volunteer donors of stem cells. | Experimental hematology 20040101 |
Nickel-induced down-regulation of serpin by hypoxic signaling. | Toxicology and applied pharmacology 20040101 |
5-Aza-2'-deoxycitydine induces demethylation and up-regulates transcription of p16INK4A gene in human gastric cancer cell lines. | Chinese medical journal 20040101 |
Role of the DNA methyltransferase variant DNMT3b3 in DNA methylation. | Molecular cancer research : MCR 20040101 |
5-azacitidine: An alternative treatment of myelodysplastic syndromes in patient with refractory response to hematopoietic growth factor, a case report and review of literatures. | Hawaii medical journal 20040101 |
Activation of expression of p15, p73 and E-cadherin in leukemic cells by different concentrations of 5-aza-2'-deoxycytidine (Decitabine). | Anticancer research 20040101 |
Apoptosis in plants: specific features of plant apoptotic cells and effect of various factors and agents. | International review of cytology 20040101 |
Enhancement of antineoplastic action of 5-aza-2'-deoxycytidine by phenylbutyrate on L1210 leukemic cells. | Leukemia & lymphoma 20040101 |
5-aza-2'-deoxycytidine restores the E-cadherin system in E-cadherin-silenced cancer cells and reduces cancer metastasis. | Clinical & experimental metastasis 20040101 |
Epigenetic CRBP downregulation appears to be an evolutionarily conserved (human and mouse) and oncogene-specific phenomenon in breast cancer. | Molecular cancer 20040101 |
Role of epigenetic DNA alterations in the pathogenesis of systemic lupus erythematosus. | Journal of applied genetics 20040101 |
Region-specific chromatin decondensation and micronucleus formation induced by 5-azacytidine in human TIG-7 cells. | Cytogenetic and genome research 20040101 |
Reversal of gene silencing as a therapeutic target for cancer--roles for DNA methylation and its interdigitation with chromatin. | Novartis Foundation symposium 20040101 |
The DNA de-methylating agent 5-azacytidine does not restore CYP1A induction in PCB resistant Newark Bay killifish (Fundulus heteroclitus). | Marine environmental research 20040101 |
Formation of mitoxantrone adducts in human tumor cells: potentiation by AN-9 and DNA methylation. | Oncology research 20040101 |
Chemically induced DNA hypomethylation in breast carcinoma cells detected by the amplification of intermethylated sites. | Breast cancer research : BCR 20040101 |
Regulation of major histocompatibility complex class II gene expression in trophoblast cells. | Reproductive biology and endocrinology : RB&E 20040101 |
Murine models of lupus induced by hypomethylated T cells. | Methods in molecular medicine 20040101 |
DNA methylation polymorphism in a set of elite rice cultivars and its possible contribution to inter-cultivar differential gene expression. | Cellular & molecular biology letters 20040101 |
New drug for bone marrow disease. | FDA consumer 20040101 |
Methylation profiles of thirty four promoter-CpG islands and concordant methylation behaviours of sixteen genes that may contribute to carcinogenesis of astrocytoma. | BMC cancer 20040101 |
[Effect of 5-azacytidine on the light-sensitive formation of sexual and asexual reproductive structures in wc-1 and wc-2 mutants of Neurospora crassa]. | Prikladnaia biokhimiia i mikrobiologiia 20040101 |
Cytotoxicity of psammaplin A from a two-sponge association may correlate with the inhibition of DNA replication. | BMC cancer 20040101 |
Nuclei of embryonic stem cells reprogram somatic cells. | Stem cells (Dayton, Ohio) 20040101 |
Neuroblastoma and pre-B lymphoma cells share expression of key transcription factors but display tissue restricted target gene expression. | BMC cancer 20040101 |
New nucleoside analogs in the treatment of solid tumors. | Acta poloniae pharmaceutica 20040101 |
Mesenchymal stem cells in the Wharton's jelly of the human umbilical cord. | Stem cells (Dayton, Ohio) 20040101 |
Treatment options for myelodysplastic syndromes. | Cancer control : journal of the Moffitt Cancer Center 20040101 |
The role of methyltransferase inhibitors in the management of the myelodysplastic syndromes. | Cancer control : journal of the Moffitt Cancer Center 20040101 |
Methyltransferase inhibitors: changing the treatment algorithm for myelodysplastic syndromes. | Cancer control : journal of the Moffitt Cancer Center 20040101 |
Microarray analysis of gene expression in metastatic gastric cancer cells after incubation with the methylation inhibitor 5-aza-2'-deoxycytidine. | Clinical & experimental metastasis 20040101 |
Approaches to the reactivation of hemoglobin F as a treatment for sickle cell disease. | Clinical advances in hematology & oncology : H&O 20040101 |
Azacitidine. | Report on carcinogens : carcinogen profiles 20040101 |
Hypermethylation of the Ink4b locus in murine myeloid leukemia and increased susceptibility to leukemia in p15(Ink4b)-deficient mice. | Oncogene 20031218 |
Identification of HRK as a target of epigenetic inactivation in colorectal and gastric cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20031215 |
Hepatocyte growth factor activator inhibitor 2/placental bikunin (HAI-2/PB) gene is frequently hypermethylated in human hepatocellular carcinoma. | Cancer research 20031215 |
[The study of 5-Aza-2'-deoxycytidine on transcription regulation of p16/CDKN2 gene demethylation in RKO human colorectal cell line]. | Zhonghua yi xue za zhi 20031210 |
Methylation of ASC/TMS1, a proapoptotic gene responsible for activating procaspase-1, in human colorectal cancer. | Cancer letters 20031208 |
Resetting the histone code at CDKN2A in HNSCC by inhibition of DNA methylation. | Oncogene 20031204 |
The heparan sulfate proteoglycan GPC3 is a potential lung tumor suppressor. | American journal of respiratory cell and molecular biology 20031201 |
Effects of 5-aza-2'-deoxycytidine on fetal hemoglobin levels, red cell adhesion, and hematopoietic differentiation in patients with sickle cell disease. | Blood 20031201 |
The histone code regulating expression of the imprinted mouse Igf2r gene. | Endocrinology 20031201 |
Promoter methylation of cyclin D2 gene in gastric carcinoma. | International journal of oncology 20031201 |
Changes in 5S rDNA chromatin organization and transcription during heterochromatin establishment in Arabidopsis. | The Plant cell 20031201 |
Epigenetic inactivation of TSLC1 gene in nasopharyngeal carcinoma. | Molecular carcinogenesis 20031201 |
DNA methylation in haematological malignancies: the role of decitabine. | Expert opinion on investigational drugs 20031201 |
Therapeutic strategies in gastric cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031201 |
DNA methylation controls the responsiveness of hepatoma cells to leukemia inhibitory factor. | Hepatology (Baltimore, Md.) 20031201 |
Altered expression of the septin gene, SEPT9, in ovarian neoplasia. | The Journal of pathology 20031201 |
Expression of pericyte, mesangium and muscle markers in malignant rhabdoid tumor cell lines: differentiation-induction using 5-azacytidine. | Cancer science 20031201 |
Proteomic analysis of pancreatic ductal carcinoma cells treated with 5-aza-2'-deoxycytidine. | Electrophoresis 20031201 |
[DNA methylation and cancer--DNA methylation as a target of cancer chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20031201 |
Synthesis and anti-cancer activity of some novel 5-azacytosine nucleosides. | Nucleosides, nucleotides & nucleic acids 20031201 |
Decitabine: development of a DNA methyltransferase inhibitor for hematological malignancies. | Current opinion in investigational drugs (London, England : 2000) 20031201 |
Demethylation of host-cell DNA at the site of avian retrovirus integration. | Biochemical and biophysical research communications 20031121 |
Upregulation of the truncated basic hair keratin 1(hHb1-DeltaN) in carcinoma cells by Epstein-Barr virus (EBV). | International journal of cancer 20031120 |
Genetic and epigenetic alterations of DLC-1 gene in hepatocellular carcinoma. | Cancer research 20031115 |
Restoration of insulin-like growth factor binding protein-related protein 1 has a tumor-suppressive activity through induction of apoptosis in human prostate cancer. | Cancer research 20031115 |
Comment on 'Chromosomal instability and tumors promoted by DNA hypomethylation' and 'Induction of tumors in nice by genomic hypomethylation'. | Science (New York, N.Y.) 20031114 |
Aberrant methylation of the cyclin D2 promoter in primary small cell, nonsmall cell lung and breast cancers. | International journal of cancer 20031110 |
Silencing of CDX2 expression in colon cancer via a dominant repression pathway. | The Journal of biological chemistry 20031107 |
Decitabine induces cell cycle arrest at the G1 phase via p21(WAF1) and the G2/M phase via the p38 MAP kinase pathway. | Leukemia research 20031101 |
ASC/TMS1, a caspase-1 activating adaptor, is downregulated by aberrant methylation in human melanoma. | International journal of cancer 20031101 |
Human circulating CD14+ monocytes as a source of progenitors that exhibit mesenchymal cell differentiation. | Journal of leukocyte biology 20031101 |
Apoptosis of terminal hypertrophic chondrocytes in an in vitro model of endochondral ossification. | The Journal of pathology 20031101 |
Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer. | Cancer research 20031101 |
Decitabine. | Current opinion in oncology 20031101 |
Epigenetic silencing of the HIC-1 gene in human medulloblastomas. | Journal of neuropathology and experimental neurology 20031101 |
Arabidopsis MBD proteins show different binding specificities and nuclear localization. | Plant molecular biology 20031101 |
Role of promoter methylation in regulation of the mammalian heparanase gene. | Oncogene 20031030 |
Epigenetic inactivation of RASSF1A candidate tumor suppressor gene at 3p21.3 in brain tumors. | Oncogene 20031030 |
Strategies for reversing drug resistance. | Oncogene 20031020 |
Transcriptional regulation of mouse delta-opioid receptor gene by CpG methylation: involvement of Sp3 and a methyl-CpG-binding protein, MBD2, in transcriptional repression of mouse delta-opioid receptor gene in Neuro2A cells. | The Journal of biological chemistry 20031017 |
Functional and molecular characterization of the epithelioid to round transition in human colorectal cancer LoVo cells. | Oncogene 20031016 |
Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma. | Oncogene 20031009 |
Inhibitors of DNA methylation and histone deacetylation activate cytomegalovirus promoter-controlled reporter gene expression in human glioblastoma cell line U87. | Carcinogenesis 20031001 |
Demethylation of the human telomerase catalytic subunit (hTERT) gene promoter reduced hTERT expression and telomerase activity and shortened telomeres. | Experimental cell research 20031001 |
Down-regulation of a novel actin-binding molecule, skeletrophin, in malignant melanoma. | The American journal of pathology 20031001 |
Reduced expression of oestrogen receptor beta in invasive breast cancer and its re-expression using DNA methyl transferase inhibitors in a cell line model. | The Journal of pathology 20031001 |
Improvement of neurological deficits by intracerebral transplantation of human adipose tissue-derived stromal cells after cerebral ischemia in rats. | Experimental neurology 20031001 |
Methylation-associated silencing of the thrombospondin-1 gene in human neuroblastoma. | Cancer research 20031001 |
DNA methylation and autoimmune disease. | Clinical immunology (Orlando, Fla.) 20031001 |
Inhibitors of DNA methylation in the treatment of hematological malignancies and MDS. | Clinical immunology (Orlando, Fla.) 20031001 |
Reactivation of fetal hemoglobin in adult stem cell erythropoiesis by transforming growth factor-beta. | Journal of hematotherapy & stem cell research 20031001 |
A novel histone deacetylase inhibitor, scriptaid, enhances expression of functional estrogen receptor alpha (ER) in ER negative human breast cancer cells in combination with 5-aza 2'-deoxycytidine. | Breast cancer research and treatment 20031001 |
Novel biospecific agents for the treatment of myelodysplastic syndromes. | Journal of the National Comprehensive Cancer Network : JNCCN 20031001 |
Effects of histone deacetylation and DNA methylation on the constitutive and TCDD-inducible expressions of the human CYP1 family in MCF-7 and HeLa cells. | Toxicology letters 20030930 |
Forced expression of the H11 heat shock protein can be regulated by DNA methylation and trigger apoptosis in human cells. | The Journal of biological chemistry 20030926 |
Clinicopathological significance and molecular regulation of maspin expression in ductal adenocarcinoma of the pancreas. | Cancer letters 20030925 |
Suppression of the protein tyrosine phosphatase receptor type O gene (PTPRO) by methylation in hepatocellular carcinomas. | Oncogene 20030925 |
Decreased methylation and transcription repressor Sp3 up-regulated human monoamine oxidase (MAO) B expression during Caco-2 differentiation. | The Journal of biological chemistry 20030919 |
Expression profiling reveals that methylation of TIMP3 is involved in uveal melanoma development. | International journal of cancer 20030910 |
Epigenetic characteristics and development of embryos cloned from donor cells treated by trichostatin A or 5-aza-2'-deoxycytidine. | Biology of reproduction 20030901 |
Mutations and aberrant DNA methylation of the PROX1 gene in hematologic malignancies. | Genes, chromosomes & cancer 20030901 |
Effect of promoter methylation on the regulation of IFN-gamma gene during in vitro differentiation of human peripheral blood T cells into a Th2 population. | Journal of immunology (Baltimore, Md. : 1950) 20030901 |
Epigenetic inactivation of RASSF1A in head and neck cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030901 |
Differential expression of bikunin (HAI-2/PB), a proposed mediator of glioma invasion, by demethylation treatment. | Journal of neuro-oncology 20030901 |
Human pancreatic carcinoma cells activate maspin expression through loss of epigenetic control. | Neoplasia (New York, N.Y.) 20030901 |
Application of mesenchymal stem cells for the regeneration of cardiomyocyte and its use for cell transplantation therapy. | Human cell 20030901 |
Molecular cloning and characterization of human acid sensing ion channel (ASIC)2 gene promoter. | Gene 20030814 |
Alterations of BLU, a candidate tumor suppressor gene on chromosome 3p21.3, in human nasopharyngeal carcinoma. | International journal of cancer 20030810 |
Role of hMLH1 promoter hypermethylation in drug resistance to 5-fluorouracil in colorectal cancer cell lines. | International journal of cancer 20030810 |
CpG methylation-dependent repression of the human O6-methylguanine-DNA methyltransferase gene linked to chromatin structure alteration. | Carcinogenesis 20030801 |
Down-regulation of FEZ1/LZTS1 gene with frequent loss of heterozygosity in oral squamous cell carcinomas. | International journal of oncology 20030801 |
Results of decitabine (5-aza-2'deoxycytidine) therapy in 130 patients with chronic myelogenous leukemia. | Cancer 20030801 |
Analysis of specific lysine histone H3 and H4 acetylation and methylation status in clones of cells with a gene silenced by nickel exposure. | Toxicology and applied pharmacology 20030801 |
Aberrant promoter methylation of the transcription factor genes PAX5 alpha and beta in human cancers. | Cancer research 20030801 |
Lsh-deficient murine embryonal fibroblasts show reduced proliferation with signs of abnormal mitosis. | Cancer research 20030801 |
Epigenetic down-regulation of death-associated protein kinase in lung cancers. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030801 |
Interleukin 12-based immunotherapy improves the antitumor effectiveness of a low-dose 5-Aza-2'-deoxycitidine treatment in L1210 leukemia and B16F10 melanoma models in mice. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030801 |
Use of adult marrow mesenchymal stem cells for regeneration of cardiomyocytes. | Bone marrow transplantation 20030801 |
Effect of fetal hemoglobin-stimulating medicines on the interaction of DNA and protein of important erythroid regulatory elements. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20030801 |
S-adenosyl-L-methionine is able to reverse micronucleus formation induced by sodium arsenite and other cytoskeleton disrupting agents in cultured human cells. | Mutation research 20030725 |
Promoter hypomethylation of a novel cancer/testis antigen gene CAGE is correlated with its aberrant expression and is seen in premalignant stage of gastric carcinoma. | Biochemical and biophysical research communications 20030718 |
Promoter methylation and silencing of the tissue factor pathway inhibitor-2 (TFPI-2), a gene encoding an inhibitor of matrix metalloproteinases in human glioma cells. | Oncogene 20030717 |
UQCRH gene encoding mitochondrial Hinge protein is interrupted by a translocation in a soft-tissue sarcoma and epigenetically inactivated in some cancer cell lines. | Oncogene 20030717 |
Frequent epigenetic inactivation of the SLIT2 gene in gliomas. | Oncogene 20030717 |
Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers. | Cancer research 20030715 |
Rapid deterioration in quality of life during interleukin-2- and alpha-interferon-based home therapy of renal cell carcinoma is associated with a good outcome. | British journal of cancer 20030707 |
Control mechanisms in the regulation of telomerase reverse transcriptase expression in differentiating human teratocarcinoma cells. | Biochemical and biophysical research communications 20030704 |
Induction of a senescent-like phenotype does not confer the ability of bovine immortal cells to support the development of nuclear transfer embryos. | Biology of reproduction 20030701 |
Effect of trichostatin a and 5'-azacytidine on transgene reactivation in U937 transduced cells. | Pharmacological research 20030701 |
OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer. | Nature genetics 20030701 |
Sera from liver failure patients and a demethylating agent stimulate transdifferentiation of murine bone marrow cells into hepatocytes in coculture with nonparenchymal liver cells. | Journal of hepatology 20030701 |
Epigenetic inactivation of laminin-5-encoding genes in lung cancers. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030701 |
Transcoronary implantation of bone marrow stromal cells ameliorates cardiac function after myocardial infarction. | The Journal of thoracic and cardiovascular surgery 20030701 |
Restoration of silenced Peutz-Jeghers syndrome gene, LKB1, induces apoptosis in pancreatic carcinoma cells. | Neoplasia (New York, N.Y.) 20030701 |
Stable transgene expression and random gene silencing in wheat. | Plant biotechnology journal 20030701 |
Establishment and functional validation of a structural homology model for human DNA methyltransferase 1. | Biochemical and biophysical research communications 20030627 |
Epigenetic silencing of multiple interferon pathway genes after cellular immortalization. | Oncogene 20030626 |
Five new human cancer-germline genes identified among 12 genes expressed in spermatogonia. | International journal of cancer 20030620 |
Methylation-regulated expression of HLA class I antigens in melanoma. | International journal of cancer 20030620 |
Transcriptional silencing of the DLC-1 tumor suppressor gene by epigenetic mechanism in gastric cancer cells. | Oncogene 20030619 |
Allelic loss on chromosome 3p21.3 and promoter hypermethylation of semaphorin 3B in non-small cell lung cancer. | Cancer research 20030615 |
Hypermethylation of the tumor suppressor gene RASSFIA and frequent concomitant loss of heterozygosity at 3p21 in cervical cancers. | International journal of cancer 20030610 |
Reconstitution of TIMP-2 expression in SH-SY5Y neuroblastoma cells by 5-azacytidine is mediated transcriptionally by NF-Y through an inverted CCAAT site. | Experimental cell research 20030610 |
Mutant p53 and aberrant cytosine methylation cooperate to silence gene expression. | Oncogene 20030605 |
The mechanism of 3'-azido-2',3'-dideoxythymidine resistance to human lymphoid cells. | International journal of molecular medicine 20030601 |
5-Aza-2'-deoxycytidine (decitabine) treatment of hematopoietic malignancies: a multimechanism therapeutic approach? | Blood 20030601 |
Inactivation of helicase-like transcription factor by promoter hypermethylation in human gastric cancer. | Molecular carcinogenesis 20030601 |
DNA mismatch repair genes in renal cell carcinoma. | The Journal of urology 20030601 |
Continuing primordial germ cell differentiation in the mouse embryo is a cell-intrinsic program sensitive to DNA methylation. | Developmental biology 20030601 |
Cell-autonomous mechanisms and myelin-associated factors contribute to the development of Purkinje axon intracortical plexus in the rat cerebellum. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030601 |
Aberrant methylation of the vascular endothelial growth factor receptor-1 gene in prostate cancer. | Cancer science 20030601 |
Proteomic analysis of a lymphoma-derived cell line (DG75) following treatment with a demethylating drug: modification of membrane-associated proteins. | Proteomics 20030601 |
DNA methylation and chromatin structure regulate T cell perforin gene expression. | Journal of immunology (Baltimore, Md. : 1950) 20030515 |
Use of the rpoB gene to determine the specificity of base substitution mutations on the Escherichia coli chromosome. | DNA repair 20030513 |
Hypermethylation, but not LOH, is associated with the low expression of MT1G and CRABP1 in papillary thyroid carcinoma. | International journal of cancer 20030510 |
Susceptibility to postnatal growth retardation induced by 5-AZA-2'-deoxycytidine in utero: gender specificity and correlation with reduced insulin-like growth factor 1. | Life sciences 20030509 |
Preclinical evaluation of antineoplastic activity of inhibitors of DNA methylation (5-aza-2'-deoxycytidine) and histone deacetylation (trichostatin A, depsipeptide) in combination against myeloid leukemic cells. | Leukemia research 20030501 |
Inactivation of deoxycytidine kinase and overexpression of P-glycoprotein in AraC and daunorubicin double resistant leukemic cell lines. | Leukemia research 20030501 |
5-azacytidine reactivates the erythroid differentiation potential of the myeloid-restricted murine cell line 32D Ro. | Experimental cell research 20030501 |
Cytosine methylation occurs in a CDC48 homologue and a MADS-box gene during adventitious shoot induction in Petunia leaf explants. | Journal of experimental botany 20030501 |
Reactivation of tumor suppressor genes by the cardiovascular drugs hydralazine and procainamide and their potential use in cancer therapy. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030501 |
Transcriptional silencing of geminiviral promoter-driven transgenes following homologous virus infection. | Molecular plant-microbe interactions : MPMI 20030501 |
Growth and differentiation of rat bone marrow stromal cells: does 5-azacytidine trigger their cardiomyogenic differentiation? | Cardiovascular research 20030501 |
The DNA methylation inhibitor 5-azacytidine modulates 6-thioguanine toxicity in mammalian cells. | Toxicology letters 20030430 |
JunB gene expression is inactivated by methylation in chronic myeloid leukemia. | Blood 20030415 |
DNA hypermethylation near the transcription start site of collagen alpha2(I) gene occurs in both cancer cell lines and primary colorectal cancers. | Cancer research 20030415 |
Immortalization of bovine capillary endothelial cells by hTERT alone involves inactivation of endogenous p16INK4A/pRb. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030401 |
Methylation of TFPI-2 gene is not the sole cause of its silencing. | International journal of oncology 20030401 |
Upregulation of galectin-7 in murine lymphoma cells is associated with progression toward an aggressive phenotype. | Leukemia 20030401 |
Methylation of cyclin D2 is observed frequently in pancreatic cancer but is also an age-related phenomenon in gastrointestinal tissues. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030401 |
Methyl-CpG-DNA binding proteins in human prostate cancer: expression of CXXC sequence containing MBD1 and repression of MBD2 and MeCP2. | Biochemical and biophysical research communications 20030321 |
Regulatory approvals of pediatric oncology drugs: previous experience and new initiatives. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030315 |
Inactivation of hMLH1 and hMSH2 by promoter methylation in primary non-small cell lung tumors and matched sputum samples. | The Journal of clinical investigation 20030315 |
Inhibition of DNA methylation and reactivation of silenced genes by zebularine. | Journal of the National Cancer Institute 20030305 |
Induction of fetal hemoglobin expression by the histone deacetylase inhibitor apicidin. | Blood 20030301 |
Long-term follow-up of a phase I study of high-dose decitabine, busulfan, and cyclophosphamide plus allogeneic transplantation for the treatment of patients with leukemias. | Cancer 20030301 |
A systematic profile of DNA methylation in human cancer cell lines. | Cancer research 20030301 |
Detection of hypermethylated RIZ1 gene in primary tumor, mouth, and throat rinsing fluid, nasopharyngeal swab, and peripheral blood of nasopharyngeal carcinoma patient. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030301 |
Interaction of 5-aza-2'-deoxycytidine and depsipeptide on antineoplastic activity and activation of 14-3-3sigma, E-cadherin and tissue inhibitor of metalloproteinase 3 expression in human breast carcinoma cells. | Anti-cancer drugs 20030301 |
Transformation of adult mesenchymal stem cells isolated from the fatty tissue into cardiomyocytes. | The Annals of thoracic surgery 20030301 |
Phase I trial of continuous infusion 5-aza-2'-deoxycytidine. | Cancer chemotherapy and pharmacology 20030301 |
Opposite effects of the maternal immune system activated by interleukin-1beta vs. PSK and OK432 on 5-azacytidine-induced birth defects. | Congenital anomalies 20030301 |
Epigenetics: the role of methylation in the mechanism of action of tumor suppressor genes. | Annals of the New York Academy of Sciences 20030301 |
E-cadherin expression is silenced by DNA methylation in cervical cancer cell lines and tumours. | European journal of cancer (Oxford, England : 1990) 20030301 |
Therapies to increase fetal hemoglobin in sickle cell disease. | Current hematology reports 20030301 |
Regeneration of cardiomyocytes from bone marrow: Use of mesenchymal stem cell for cardiovascular tissue engineering. | Cytotechnology 20030301 |
Effects of 5-aza-2'-deoxycytidine on matrix metalloproteinase expression and pancreatic cancer cell invasiveness. | Journal of the National Cancer Institute 20030219 |
On the use of DNA methylation inhibitors and the reversal of transcriptional silencing. | Blood 20030215 |
CpG island methylation is a common finding in colorectal cancer cell lines. | British journal of cancer 20030210 |
Hypermethylation-mediated regulation of CD44 gene expression in human neuroblastoma. | Genes, chromosomes & cancer 20030201 |
Methylation status of promoters and expression of MUC2 and MUC5AC mucins in pancreatic cancer cells. | International journal of oncology 20030201 |
Hypomethylation of the synuclein gamma gene CpG island promotes its aberrant expression in breast carcinoma and ovarian carcinoma. | Cancer research 20030201 |
Hypermethylation of the gene promoter and enhancer region can regulate Fas expression and sensitivity in colon carcinoma. | Cell death and differentiation 20030201 |
Latent HIV-1 reactivation in transgenic mice requires cell cycle -dependent demethylation of CREB/ATF sites in the LTR. | AIDS (London, England) 20030124 |
Role of DNA methylation in the suppression of Apaf-1 protein in human leukaemia. | Oncogene 20030123 |
Promoter hypermethylation of DLC-1, a candidate tumor suppressor gene, in several common human cancers. | Cancer genetics and cytogenetics 20030115 |
Synergistic antineoplastic action of DNA methylation inhibitor 5-AZA-2'-deoxycytidine and histone deacetylase inhibitor depsipeptide on human breast carcinoma cells. | International journal of cancer 20030110 |
Detection of thymidylate synthase modulators by a novel screening assay. | Molecular pharmacology 20030101 |
Regulation of mouse mammary tumor virus env transcriptional activator initiated mammary tumor virus superantigen transcripts in lymphomas of SJL/J mice: role of Ikaros, demethylation, and chromatin structural change in the transcriptional activation of mammary tumor virus superantigen. | Journal of immunology (Baltimore, Md. : 1950) 20030101 |
Hypermethylation of metallothionein-3 CpG island in gastric carcinoma. | Carcinogenesis 20030101 |
Chromosomal aberrations induced by 5-azacytidine combined with VP-16 (etoposide) in CHO-K1 and XRS-5 cell lines. | Teratogenesis, carcinogenesis, and mutagenesis 20030101 |
5-AZA-2'-deoxycytidine (5-AZA-CdR): a demethylating agent affecting development and reproductive capacity. | Journal of applied toxicology : JAT 20030101 |
Down-regulation of connexin 32 gene expression through DNA methylation in a human renal cell carcinoma cell. | American journal of nephrology 20030101 |
An epigenetic approach for finding tumor suppressors. | Cell cycle (Georgetown, Tex.) 20030101 |
Hypermethylation of death-associated protein (DAP) kinase CpG island is frequent not only in B-cell but also in T- and natural killer (NK)/T-cell malignancies. | Cancer science 20030101 |
Decitabine: 2'-deoxy-5-azacytidine, Aza dC, DAC, dezocitidine, NSC 127716. | Drugs in R&D 20030101 |
Inactivation of the RASSF1A in osteosarcoma. | Oncology reports 20030101 |
Induced differentiation of human cord blood mesenchymal stem/progenitor cells into cardiomyocyte-like cells in vitro. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20030101 |
Reactivation of silenced genes and transcriptional therapy. | Cytogenetic and genome research 20030101 |
Forgotten fragile sites and related phenomena. | Cytogenetic and genome research 20030101 |
Synthesis of 5-azacytidine nucleosides with rigid sugar moiety as potential antitumor agents. | Nucleosides, nucleotides & nucleic acids 20030101 |
5-aza-2'-deoxycytidine induces alterations in murine spermatogenesis and pregnancy outcome. | Journal of andrology 20030101 |
Decitabine: 2'-deoxy-5-azacytidine, Aza dC, DAC, dezocitidine, NSC 127716. | Drugs in R&D 20030101 |
Specific inhibition of DNMT1 by antisense oligonucleotides induces re-expression of estrogen receptor-alpha (ER) in ER-negative human breast cancer cell lines. | Cancer biology & therapy 20030101 |
Induction of the estrogen receptor by ablation of DNMT1 in ER-negative breast cancer cells. | Cancer biology & therapy 20030101 |
Hemoglobinopathies. | Hematology. American Society of Hematology. Education Program 20030101 |
Myelodysplastic syndrome. | Hematology. American Society of Hematology. Education Program 20030101 |
Positive and negative transcriptional states of a variegating immunoglobulin heavy chain (IgH) locus are maintained by a cis-acting epigenetic mechanism. | Journal of immunology (Baltimore, Md. : 1950) 20021215 |
Dependence of histone modifications and gene expression on DNA hypermethylation in cancer. | Cancer research 20021215 |
The architecture of interphase chromosomes and gene positioning are altered by changes in DNA methylation and histone acetylation. | Journal of cell science 20021201 |
An ACF1-ISWI chromatin-remodeling complex is required for DNA replication through heterochromatin. | Nature genetics 20021201 |
Induction of TRAG-3 expression in A549 lung adenocarcinoma cell line by 5-aza-2' deoxyazacytidine. | Lung cancer (Amsterdam, Netherlands) 20021201 |
Expression of Arabidopsis LINEs from two promoters. | The Plant journal : for cell and molecular biology 20021201 |
Down-regulation of PIK3CG, a catalytic subunit of phosphatidylinositol 3-OH kinase, by CpG hypermethylation in human colorectal carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20021201 |
DNA methylation and demethylating drugs in myelodysplastic syndromes and secondary leukemias. | Haematologica 20021201 |
Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma. | Cancer cell 20021201 |
Decitabine has promising clinical activity in chronic myeloid leukemia. | Expert review of anticancer therapy 20021201 |
The human telomerase RNA gene (hTERC) is regulated during carcinogenesis but is not dependent on DNA methylation. | Carcinogenesis 20021201 |
Inhibition of growth of mouse gastric cancer cells by Runx3, a novel tumor suppressor. | Oncogene 20021128 |
Effect of azacytidine in the release of leukemia inhibitory factor, oncostatin m, interleukin (IL)-6, and IL-11 by mononuclear cells of patients with refractory anemia. | Cytokine 20021124 |
[Myelodysplastic syndromes. Diagnosis and therapeutic strategies]. | Medizinische Klinik (Munich, Germany : 1983) 20021115 |
Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine. | Cancer research 20021115 |
The ETS transcription factor MEF is a candidate tumor suppressor gene on the X chromosome. | Cancer research 20021115 |
DNA methyltransferase inhibitors-state of the art. | Annals of oncology : official journal of the European Society for Medical Oncology 20021101 |
Re-expression of p16 gene in the myeloma cell line U266 induced by synergy of sodium butyrate and 5-Aza-2'-deoxycytidine. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20021101 |
[The re-expression of p15(INK4B) gene in leukemia cells induced by in vitro DNA methyltransferase and histone deacetylase inhibition]. | Zhonghua nei ke za zhi 20021101 |
New synthesis of pyrrolidine homoazasugars via aminohomologation of furanoses and their use for the stereoselective synthesis of aza-C-disaccharides. | The Journal of organic chemistry 20021018 |
Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment. | Blood 20021015 |
Crucial role of DNA methylation in determination of clonally distributed killer cell Ig-like receptor expression patterns in NK cells. | Journal of immunology (Baltimore, Md. : 1950) 20021015 |
Deregulation of caspase 8 and 10 expression in pediatric tumors and cell lines. | Cancer research 20021015 |
Estrogen receptor alpha-mediated silencing of caveolin gene expression in neuronal cells. | The Journal of biological chemistry 20021011 |
Inhibition of HhaI DNA (Cytosine-C5) methyltransferase by oligodeoxyribonucleotides containing 5-aza-2'-deoxycytidine: examination of the intertwined roles of co-factor, target, transition state structure and enzyme conformation. | Journal of molecular biology 20021011 |
[Cell transplantation of 5-aza cytidine induced bone marrow stromal cells transfected by angiogenin gene ex vivo into infarcted myocardium, an experimental study]. | Zhonghua yi xue za zhi 20021010 |
Treatment of myelodysplastic syndromes with 5-azacytidine. | Leukemia research 20021001 |
Histone modifications depict an aberrantly heterochromatinized FMR1 gene in fragile x syndrome. | American journal of human genetics 20021001 |
Evidence for local control of gene expression in the epidermal differentiation complex. | Experimental dermatology 20021001 |
Seeking a way to alleviate sickle cell disease. | JAMA 20021001 |
Phase II trial of cisplatin plus decitabine, a new DNA hypomethylating agent, in patients with advanced squamous cell carcinoma of the cervix. | American journal of clinical oncology 20021001 |
Suppression of metallothionein-I/II expression and its probable molecular mechanisms. | Environmental health perspectives 20021001 |
Reprogramming of bone marrow mesenchymal stem cells into cardiomyocytes. | Comptes rendus biologies 20021001 |
[Apoptosis and re-expression of p16 gene in the myeloma cell line U266 induced by synergy of histone deacetylase inhibitor and demethylating agent]. | Ai zheng = Aizheng = Chinese journal of cancer 20021001 |
DNA methylation down-regulates CDX1 gene expression in colorectal cancer cell lines. | The Journal of biological chemistry 20020927 |
Tropomyosin-1, a novel suppressor of cellular transformation is downregulated by promoter methylation in cancer cells. | Cancer letters 20020926 |
Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells. | Circulation research 20020920 |
DNA alkylating agents alleviate silencing of class II transactivator gene expression in L1210 lymphoma cells. | Journal of immunology (Baltimore, Md. : 1950) 20020915 |
New drugs in acute myeloid leukemia. | Current oncology reports 20020901 |
Antineoplastic action of 5-aza-2'-deoxycytidine and phenylbutyrate on human lung carcinoma cells. | Anti-cancer drugs 20020901 |
Treatment of cancer cells with methioninase produces DNA hypomethylation and increases DNA synthesis. | Cancer research 20020815 |
Molecular changes associated with oral dysplasia progression and acquisition of immortality: potential for its reversal by 5-azacytidine. | Cancer research 20020815 |
5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy. | Oncogene 20020812 |
Reactivating the expression of methylation silenced genes in human cancer. | Oncogene 20020812 |
Pseudomyxoma peritonei is a disease of MUC2-expressing goblet cells. | The American journal of pathology 20020801 |
5-aza-2'-deoxycytidine-induced expression of functional cancer testis antigens in human renal cell carcinoma: immunotherapeutic implications. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020801 |
Role of DNA methylation in transcription of human endogenous retrovirus in the pathogenesis of systemic lupus erythematosus. | The Journal of rheumatology 20020801 |
Retinoic acid receptor alpha2 is a growth suppressor epigenetically silenced in MCF-7 human breast cancer cells. | Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 20020801 |
What is the optimal therapy for childhood AML? | Oncology (Williston Park, N.Y.) 20020801 |
Acute rhabdomyolysis as a complication of cytarabine chemotherapy for acute myeloid leukemia: case report and review of literature. | American journal of hematology 20020801 |
5-Azacytidine (5AzC)-induced histopathological changes in the central nervous system of rat fetuses. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20020801 |
[Inhibitory effect on proliferation of KG1a cell line by methyltransferase inhibitors]. | Zhongguo shi yan xue ye xue za zhi 20020801 |
Identification of active antiviral compounds against a New York isolate of West Nile virus. | Antiviral research 20020701 |
Differential expression of FEZ1/LZTS1 gene in lung cancers and their cell cultures. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020701 |
Reduced expression of the insulin-induced protein 1 and p41 Arp2/3 complex genes in human gastric cancers. | International journal of cancer 20020701 |
SNPs in the CpG island of NAP1L2: a possible link between DNA methylation and neural tube defects? | American journal of medical genetics 20020701 |
Chemoprevention of hepatocarcinogenesis: S-adenosyl-L-methionine. | Alcohol (Fayetteville, N.Y.) 20020701 |
Progressive aberrant methylation of the RASSF1A gene in simian virus 40 infected human mesothelial cells. | Oncogene 20020620 |
Inactivation of O6-methylguanine-DNA methyltransferase by promoter CpG island hypermethylation in gastric cancers. | British journal of cancer 20020617 |
DNA hypomethylating agents 5-aza-2'-deoxycytidine and valproate increase neuronal 5-lipoxygenase mRNA. | European journal of pharmacology 20020607 |
Silencing of pi-class glutathione S-transferase in MDA PCa 2a and MDA PCa 2b cells. | The Prostate 20020601 |
Maintenance of elevated fetal hemoglobin levels by decitabine during dose interval treatment of sickle cell anemia. | Blood 20020601 |
DNA methylation dominates transcriptional silencing of Pax5 in terminally differentiated B cell lines. | Molecular immunology 20020601 |
Improved heart function with myogenesis and angiogenesis after autologous porcine bone marrow stromal cell transplantation. | The Journal of thoracic and cardiovascular surgery 20020601 |
Remodeling of DNA methylation and phenotypic and transcriptional changes in synthetic Arabidopsis allotetraploids. | Plant physiology 20020601 |
DNA methylation and epigenetic inheritance. | Methods (San Diego, Calif.) 20020601 |
Mechanisms of 5-azacytidine (5AzC)-induced toxicity in the rat foetal brain. | International journal of experimental pathology 20020601 |
Aberrant methylation of the ATM promoter correlates with increased radiosensitivity in a human colorectal tumor cell line. | Oncogene 20020530 |
Cytotoxic activity of 2',2'-difluorodeoxycytidine, 5-aza-2'-deoxycytidine and cytosine arabinoside in cells transduced with deoxycytidine kinase gene. | Biochemical and biophysical research communications 20020524 |
In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer. | British journal of cancer 20020520 |
Treatment of myelodysplastic syndrome: questions raised by the azacitidine experience. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020515 |
Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: a study of the cancer and leukemia group B. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020515 |
Impact of azacytidine on the quality of life of patients with myelodysplastic syndrome treated in a randomized phase III trial: a Cancer and Leukemia Group B study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020515 |
Role of de novo DNA methyltransferases and methyl CpG-binding proteins in gene silencing in a rat hepatoma. | The Journal of biological chemistry 20020503 |
Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers. | Oncogene 20020502 |
Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020501 |
Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus. | Arthritis and rheumatism 20020501 |
Hypertonicity induction of melanoma antigen, a tumor-associated antigen. | Molecules and cells 20020430 |
Genetics of cellular senescence. | Mechanisms of ageing and development 20020430 |
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
Cell division is required for de novo methylation of CpG islands in bladder cancer cells. | Cancer research 20020415 |
Differentiation therapy for myelodysplastic syndrome. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020401 |
Silencing of GSTP1 gene by CpG island DNA hypermethylation in HBV-associated hepatocellular carcinomas. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020401 |
5-Aza-2'-deoxycytidine-induced cytotoxicity and limb reduction defects in the mouse. | Teratology 20020401 |
Review of the clinical experience with 5-azacytidine and 5-aza-2'-deoxycytidine in solid tumors. | Current opinion in investigational drugs (London, England : 2000) 20020401 |
Cancer testis antigens expression in mesothelioma: role of DNA methylation and bioimmunotherapeutic implications. | British journal of cancer 20020318 |
p16INK4a loss and sensitivity in KSHV associated primary effusion lymphoma. | Oncogene 20020314 |
High prevalence of decreased expression of KAI1 metastasis suppressor in human oral carcinogenesis. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020301 |
Complex relationships between 5-aza-dC induced DNA demethylation and chromosome compaction at mitosis. | Chromosoma 20020301 |
Molecular characterization of regenerated cardiomyocytes derived from adult mesenchymal stem cells. | Congenital anomalies 20020301 |
Reduced expression of insulin-like growth factor binding protein-3 and its promoter hypermethylation in human hepatocellular carcinoma. | Cancer letters 20020225 |
Chromosomal autonomy of hMLH1 methylation in colon cancer. | Oncogene 20020221 |
Methylation-mediated silencing of TMS1/ASC is accompanied by histone hypoacetylation and CpG island-localized changes in chromatin architecture. | The Journal of biological chemistry 20020215 |
Somatic recombination: a major genotoxic effect of two pyrimidine antimetabolitic chemotherapeutic drugs in Drosophila melanogaster. | Mutation research 20020215 |
Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2'-deoxycytidine. | Cancer research 20020215 |
The 5-lipoxygenase promoter is regulated by DNA methylation. | The Journal of biological chemistry 20020208 |
Cancer research. Leukemia protein spurs gene silencing. | Science (New York, N.Y.) 20020208 |
Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor. | Science (New York, N.Y.) 20020208 |
Frequent allelic losses on the short arm of chromosome 1 and decreased expression of the p73 gene at 1p36.3 in squamous cell carcinoma of the oral cavity. | International journal of oncology 20020201 |
Lack of IFN-gamma-mediated induction of the class II transactivator (CIITA) through promoter methylation is predominantly found in developmental tumor cell lines. | International journal of cancer 20020201 |
Chondrocytes provide morphogenic signals that selectively induce osteogenic differentiation of mesenchymal stem cells. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20020201 |
Expression of a human endogenous retrovirus, HERV-K, in the blood cells of leukemia patients. | Leukemia 20020201 |
5S rRNA genes expression is not inhibited by DNA methylation in Arabidopsis. | The Plant journal : for cell and molecular biology 20020201 |
Lack of a consistent relationship between demethylation of the CD44 promoter and CD44 expression. | Immunogenetics 20020201 |
Variable promoter region CpG island methylation of the putative tumor suppressor gene Connexin 26 in breast cancer. | Carcinogenesis 20020201 |
Treatment of thalassoemia--the current scenario. | Journal of the Indian Medical Association 20020201 |
Transcriptional silencing and developmental reactivation of cry1Ab gene in transgenic rice. | Science in China. Series C, Life sciences 20020201 |
Bone marrow-derived regenerated cardiomyocytes (CMG Cells) express functional adrenergic and muscarinic receptors. | Circulation 20020122 |
Aberrant methylation and histone deacetylation of cyclooxygenase 2 in gastric cancer. | International journal of cancer 20020120 |
Characterization of XAGE-1b, a short major transcript of cancer/testis-associated gene XAGE-1, induced in melanoma metastasis. | International journal of cancer 20020110 |
DNA methylation regulates the expression of Y chromosome specific genes in prostate cancer. | The Journal of urology 20020101 |
Specific patterns of gene methylation in natural killer cell lymphomas : p73 is consistently involved. | The American journal of pathology 20020101 |
Novel agents for the therapy of acute leukemia. | Current opinion in oncology 20020101 |
Primary acute myeloid leukaemia blasts resistant to cytokine-induced differentiation to dendritic-like leukaemia cells can be forced to differentiate by the addition of bryostatin-1. | Leukemia 20020101 |
The opposed effect of 5-azacytidine and light on the development of reproductive structures in Neurospora crassa. | Photochemistry and photobiology 20020101 |
Sequential observations of exencephaly and subsequent morphological changes by mouse exo utero development system: analysis of the mechanism of transformation from exencephaly to anencephaly. | Anatomy and embryology 20020101 |
De novo expression of the Muc2 gene in pancreas carcinoma cells is triggered by promoter demethylation. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20020101 |
Promoter methylation controls the expression of MAGE2, 3 and 4 genes in human cutaneous melanoma. | Journal of immunotherapy (Hagerstown, Md. : 1997) 20020101 |
New approaches to the treatment of myelodysplasia. | The oncologist 20020101 |
Analysis of promoter methylation and its role in silencing metallothionein I gene expression in tumor cells. | Methods in enzymology 20020101 |
Expression spectrum and methylation-dependent regulation of melanoma antigen-encoding gene family members in pancreatic cancer cells. | Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20020101 |
Expression of ribosomal protein L4 (rpL4) during neurogenesis and 5-azacytidine (5AzC)-induced apoptotic process in the rat. | Histology and histopathology 20020101 |
Methylation state of the prostate specific membrane antigen (PSMA) CpG island in prostate cancer cell lines. | Anticancer research 20020101 |
[Effect of 5-azacytidine on expression of DNA sequences homologous to ENV gene of murine mammary tumor virus in normal human lymphocytes]. | Molekuliarnaia genetika, mikrobiologiia i virusologiia 20020101 |
Identification of genes involved in ceramide-dependent neuronal apoptosis using cDNA arrays. | Genome biology 20020101 |
MYEOV, a gene at 11q13, is coamplified with CCND1, but epigenetically inactivated in a subset of esophageal squamous cell carcinomas. | Journal of human genetics 20020101 |
Reactivation of a silenced H19 gene in human rhabdomyosarcoma by demethylation of DNA but not by histone hyperacetylation. | Molecular cancer 20020101 |
Cyclin D2 expression in familial and sporadic breast cancer. | Oncology reports 20020101 |
[Telomerase: an enzyme with multiple applications in cancer research]. | Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20020101 |
Aberrant methylation of the 5' CpG island of TSLC1 is common in pancreatic ductal adenocarcinoma and is first manifest in high-grade PanlNs. | Cancer biology & therapy 20020101 |
Characteristic promoter hypermethylation signatures in male germ cell tumors. | Molecular cancer 20020101 |
5-aza-2'-deoxycytidine induces retinoic acid receptor beta 2 demethylation, cell cycle arrest and growth inhibition in breast carcinoma cells. | Anticancer research 20020101 |
A proapoptotic caspase recruitment domain protein gene, TMS1, is hypermethylated in human breast and gastric cancers. | Anticancer research 20020101 |
Roles of histone acetylation in the Dnmt1 gene expression. | Nucleic acids research. Supplement (2001) 20020101 |
Azacitidine. | Report on carcinogens : carcinogen profiles 20020101 |
DNA methylation of the human oxytocin receptor gene promoter regulates tissue-specific gene suppression. | Biochemical and biophysical research communications 20011207 |
Identification and characterization of differentially methylated CpG islands in pancreatic carcinoma. | Cancer research 20011201 |
Potential of 5-aza-2'-deoxycytidine (Decitabine) a potent inhibitor of DNA methylation for therapy of advanced non-small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20011201 |
Reexpression of a cluster of silenced transgenes is associated with their rearrangement. | Genes, chromosomes & cancer 20011201 |
Expression of the Hypermethylated in Cancer gene (HIC-1) is associated with good outcome in human breast cancer. | British journal of cancer 20011201 |
[Chemotherapy and radiation therapy]. | Nihon rinsho. Japanese journal of clinical medicine 20011201 |
MRNA expression of genes altered by 5-azacytidine treatment in cancer cell lines is associated with clinicopathological parameters of human cancers. | Journal of cancer research and clinical oncology 20011201 |
Differential esterase expression in developmental mutants of Aspergillus nidulans. | Biochemical genetics 20011201 |
DNA from Aspergillus flavus contains 5-methylcytosine. | FEMS microbiology letters 20011127 |
Increased expression of unmethylated CDKN2D by 5-aza-2'-deoxycytidine in human lung cancer cells. | Oncogene 20011122 |
Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily. | Cancer research 20011115 |
Loss of DNA mismatch repair imparts defective cdc2 signaling and G(2) arrest responses without altering survival after ionizing radiation. | Cancer research 20011115 |
5-Aza-2'-deoxycytidine induces histone hyperacetylation of mouse centromeric heterochromatin by a mechanism independent of DNA demethylation. | Biochemical and biophysical research communications 20011109 |
E-cadherin expression is commonly downregulated by CpG island hypermethylation in esophageal carcinoma cells. | Cancer letters 20011108 |
RASSF1A promoter region CpG island hypermethylation in phaeochromocytomas and neuroblastoma tumours. | Oncogene 20011108 |
Early detection of endogenous retroviruses in chemically induced mouse cells. | Virus research 20011105 |
Inhibition of histone deacetylase activity causes cell type-specific induction of the PDGF-B promoter only in the absence of activation by its enhancer. | Experimental cell research 20011101 |
Diminished expression of S100A2, a putative tumor suppressor, at early stage of human lung carcinogenesis. | Cancer research 20011101 |
CpG methylation as a basis for breast tumor-specific loss of NES1/kallikrein 10 expression. | Cancer research 20011101 |
GSTP1 CpG island hypermethylation is responsible for the absence of GSTP1 expression in human prostate cancer cells. | The American journal of pathology 20011101 |
Glypican-3 expression is silenced in human breast cancer. | Oncogene 20011101 |
Reduced expression of intercellular adhesion molecule-1 in ovarian adenocarcinomas. | British journal of cancer 20011101 |
Methylation of episomal plasmids as a barrier to transient gene expression via a synthetic delivery vector. | Biomolecular engineering 20011031 |
Methylation-dependent silencing of the reduced folate carrier gene in inherently methotrexate-resistant human breast cancer cells. | The Journal of biological chemistry 20011026 |
Methylation in hMLH1 promoter interferes with its binding to transcription factor CBF and inhibits gene expression. | Oncogene 20011025 |
Glucocorticoid-mediated transrepression is regulated by histone acetylation and DNA methylation. | European journal of pharmacology 20011019 |
CpG hypermethylation of the promoter region inactivates the estrogen receptor-beta gene in patients with prostate carcinoma. | Cancer 20011015 |
Methylation changes in the human IGF2 p3 promoter parallel IGF2 expression in the primary tumor, established cell line, and xenograft of a human hepatoblastoma. | Experimental cell research 20011015 |
Rexpression of HLA class I antigens and restoration of antigen-specific CTL response in melanoma cells following 5-aza-2'-deoxycytidine treatment. | International journal of cancer 20011015 |
DNA hypomethylation of karyoplasts for bovine nuclear transplantation. | Molecular reproduction and development 20011001 |
DNA hypermethylation is a mechanism for loss of expression of the HLA class I genes in human esophageal squamous cell carcinomas. | Carcinogenesis 20011001 |
Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells. | Cancer research 20011001 |
Chondrocyte phenotype and cell survival are regulated by culture conditions and by specific cytokines through the expression of Sox-9 transcription factor. | Rheumatology (Oxford, England) 20011001 |
Reduced expression of syndecan-1 affects metastatic potential and clinical outcome in patients with colorectal cancer. | Japanese journal of cancer research : Gann 20011001 |
Pharmacological reactivation of inactive genes: the fragile X experience. | Brain research bulletin 20011001 |
5-azacytidine induces chromosomal breakage in the root tips of wheat carrying the cuckoo chromosome 4S(L) from Aegilops sharonensis. | Heredity 20011001 |
Brain from bone: efficient 'meta-differentiation' of marrow stroma-derived mature osteoblasts to neurons with Noggin or a demethylating agent. | Differentiation; research in biological diversity 20011001 |
Histone deacetylase and DNA methyltransferase in human prostate cancer. | Biochemical and biophysical research communications 20010928 |
Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer. | Oncogene 20010913 |
The E-cadherin gene is silenced by CpG methylation in human oral squamous cell carcinomas. | International journal of cancer 20010901 |
Promoter hypermethylation of MGMT is associated with protein loss in gastric carcinoma. | International journal of cancer 20010901 |
Loss of annexin II heavy and light chains in prostate cancer and its precursors. | Cancer research 20010901 |
Hypermethylation of CpG islands in the mouse asparagine synthetase gene: relationship to asparaginase sensitivity in lymphoma cells. Partial methylation in normal cells. | British journal of cancer 20010901 |
CpG methylation of promoter region inactivates E-cadherin gene in renal cell carcinoma. | Molecular carcinogenesis 20010901 |
Hypermethylation of the tumor necrosis factor receptor superfamily 6 (APT1, Fas, CD95/Apo-1) gene promoter at rel/nuclear factor kappaB sites in prostatic carcinoma. | Molecular carcinogenesis 20010901 |
Epigenetic regulation of the KAI1 metastasis suppressor gene in human prostate cancer cell lines. | Japanese journal of cancer research : Gann 20010901 |
Molecular mechanisms mediating methylation-dependent silencing of ribosomal gene transcription. | Molecular cell 20010901 |
Selection of drug-resistant transduced cells with cytosine nucleoside analogs using the human cytidine deaminase gene. | Cancer gene therapy 20010901 |
Alteration of DNA methylation in gastrointestinal carcinogenesis. | Journal of gastroenterology and hepatology 20010901 |
Evolving treatment options of myelodysplastic syndromes. | Annals of hematology 20010901 |
5-azaC treatment enhances expression of transforming growth factor-beta receptors through down-regulation of Sp3. | The Journal of biological chemistry 20010831 |
Molecular mechanisms for aberrant expression of the human breast cancer specific gene 1 in breast cancer cells: control of transcription by DNA methylation and intronic sequences. | Oncogene 20010823 |
Reversion of transcriptional repression of Sp1 by 5 aza-2' deoxycytidine restores TGF-beta type II receptor expression in the pancreatic cancer cell line MIA PaCa-2. | Cancer research 20010815 |
Loss of cyp1a1 messenger rna expression due to nonsense-mediated decay. | Molecular pharmacology 20010801 |
DNA methylation regulates placental lactogen I gene expression. | Endocrinology 20010801 |
Activation of the maternally preset program of apoptosis by microinjection of 5-aza-2'-deoxycytidine and 5-methyl-2'-deoxycytidine-5'-triphosphate in Xenopus laevis embryos. | Development, growth & differentiation 20010801 |
Cytogenetic responses in high-risk myelodysplastic syndrome following low-dose treatment with the DNA methylation inhibitor 5-aza-2'-deoxycytidine. | British journal of haematology 20010801 |
Inactivation of retinoic acid receptor beta by promoter CpG hypermethylation in gastric cancer. | Differentiation; research in biological diversity 20010801 |
Regulation of the intestinal mucin MUC2 gene expression in vivo: evidence for the role of promoter methylation. | Cancer letters 20010710 |
Evidence for gene silencing in Haemophilus influenzae. | Mutation research 20010701 |
Promoter hypermethylation: a common cause of reduced p16(INK4a) expression in uveal melanoma. | Cancer research 20010701 |
Valproic acid, trichostatin and their combination with hemin preferentially enhance gamma-globin gene expression in human erythroid liquid cultures. | Haematologica 20010701 |
Loss of mismatch repair activity in simian virus 40 large T antigen-immortalized BPH-1 human prostatic epithelial cell line. | Molecular carcinogenesis 20010701 |
Antineoplastic action of 5-aza-2'-deoxycytidine and histone deacetylase inhibitor and their effect on the expression of retinoic acid receptor beta and estrogen receptor alpha genes in breast carcinoma cells. | Cancer chemotherapy and pharmacology 20010701 |
Cytosine methylation represses glutathione S-transferase P1 (GSTP1) gene expression in human prostate cancer cells. | Cancer research 20010615 |
Increased sensitivity of transforming growth factor (TGF) beta 1 null cells to alkylating agents reveals a novel link between TGFbeta signaling and O(6)-methylguanine methyltransferase promoter hypermethylation. | The Journal of biological chemistry 20010601 |
Transcriptional silencing of Cyclooxygenase-2 by hyper-methylation of the 5' CpG island in human gastric carcinoma cells. | Cancer research 20010601 |
DNA methylation inhibits expression and transposition of the Neurospora Tad retrotransposon. | Molecular genetics and genomics : MGG 20010601 |
Overexpression of MnSOD protects murine fibrosarcoma cells (FSa-II) from apoptosis and promotes a differentiation program upon treatment with 5-azacytidine: involvement of MAPK and NFkappaB pathways. | Antioxidants & redox signaling 20010601 |
Decitabine with allogeneic peripheral blood stem cell transplantation in the therapy of leukemia relapse following a prior transplant: results of a phase I study. | Bone marrow transplantation 20010601 |
Loss of expression of a new member of the DNAJ protein family confers resistance to chemotherapeutic agents used in the treatment of ovarian cancer. | Cancer research 20010515 |
Induction of Tax i expression in MT-4 cells by 5-azacytidine leads to protein binding in the HTLV-1 LTR in vivo. | Virology 20010510 |
Advances in experimental treatment of beta-thalassaemia. | Expert opinion on investigational drugs 20010501 |
5' CpG island methylation of the FHIT gene is correlated with loss of gene expression in lung and breast cancer. | Cancer research 20010501 |
Two-dimensional database of a Burkitt lymphoma cell line (DG 75) proteins: protein pattern changes following treatment with 5'-azycytidine. | Electrophoresis 20010501 |
Effects of simian virus 40 T-antigens on normal human mammary epithelial cells reveal evidence for spontaneous alterations in addition to loss of p16(INK4a) expression. | Experimental cell research 20010415 |
Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications. | Annals of internal medicine 20010403 |
Maedi-visna virus, a model for in vitro testing of potential anti-HIV drugs. | Comparative immunology, microbiology and infectious diseases 20010401 |
Activation of the p53 DNA damage response pathway after inhibition of DNA methyltransferase by 5-aza-2'-deoxycytidine. | Molecular pharmacology 20010401 |
Acquired resistance of melanoma cells to the antineoplastic agent fotemustine is caused by reactivation of the DNA repair gene MGMT. | International journal of cancer 20010401 |
Association of acetylated histones with paternally expressed genes in the Prader--Willi deletion region. | Human molecular genetics 20010315 |
Association of deletions and translocation of the reduced folate carrier gene with profound loss of gene expression in methotrexate-resistant K562 human erythroleukemia cells. | Biochemical pharmacology 20010315 |
Promoter methylation regulates Helicobacter pylori-stimulated cyclooxygenase-2 expression in gastric epithelial cells. | Cancer research 20010315 |
Telomerase activity is repressed during differentiation along the hepatocytic and biliary epithelial lineages: verification on immortal cell lines from the same origin. | Cell biochemistry and function 20010301 |
Pharmacologic induction of fetal hemoglobin: raising the therapeutic bar in sickle cell disease. | Current opinion in hematology 20010301 |
Sequence of centromere separation: effect of 5-azacytidine-induced epigenetic alteration. | Mutagenesis 20010301 |
Analysis of the ANA gene as a candidate for the chromosome 21q oral cancer susceptibility locus. | British journal of cancer 20010301 |
Silencing of the caspase-1 gene occurs in murine and human renal cancer cells and causes solid tumor growth in vivo. | International journal of cancer 20010301 |
Elevation of breast carcinoma Nm23-H1 metastasis suppressor gene expression and reduced motility by DNA methylation inhibition. | Cancer research 20010301 |
Development of regenerative cardiomyocytes from mesenchymal stem cells for cardiovascular tissue engineering. | Artificial organs 20010301 |
Evidence of abundant constitutive alkali-labile sites in human 5 bp classical satellite DNA loci by DBD-FISH. | Mutation research 20010220 |
Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression. | Cancer research 20010215 |
DNA methyltransferase inhibition enhances apoptosis induced by histone deacetylase inhibitors. | Cancer research 20010215 |
Unbalanced expression of HLA-A and -B antigens: a specific feature of cutaneous melanoma and other non-hemopoietic malignancies reverted by IFN-gamma. | International journal of cancer 20010215 |
Effect of 5-Aza-2'-deoxycytidine on the P16 tumor suppressor gene in hepatocellular carcinoma cell line HepG2. | World journal of gastroenterology 20010215 |
Effects of hydroxurea, stem cell factor, and erythropoietin in combination on fetal hemoglobin in the baboon. | Experimental hematology 20010201 |
Sensitization by 5-aza-2'-deoxycytidine of leukaemia cells with MLL abnormalities to induction of differentiation by all-trans retinoic acid and 1alpha,25-dihydroxyvitamin D3. | British journal of haematology 20010201 |
A novel cell culture model of chondrocyte differentiation during mammalian endochondral ossification. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010201 |
Identification of a novel member of the snail/Gfi-1 repressor family, mlt 1, which is methylated and silenced in liver tumors of SV40 T antigen transgenic mice. | Cancer research 20010201 |
Rhesus monkey model for fetal gene transfer: studies with retroviral- based vector systems. | Molecular therapy : the journal of the American Society of Gene Therapy 20010201 |
Evidence that silencing of the HPRT promoter by DNA methylation is mediated by critical CpG sites. | The Journal of biological chemistry 20010105 |
Biallelic inactivation of retinoic acid receptor beta2 gene by epigenetic change in breast cancer. | The American journal of pathology 20010101 |
Lack of telomerase RNA gene hTERC expression in alternative lengthening of telomeres cells is associated with methylation of the hTERC promoter. | Cancer research 20010101 |
Induction of MAGE-3 expression in lung and esophageal cancer cells. | The Annals of thoracic surgery 20010101 |
Anticancer drug-induced kidney disorders. | Drug safety 20010101 |
DNA methylation contributes to tissue- and allele-specific expression of the T-cell differentiation marker RT6. | Immunogenetics 20010101 |
Transcripts of the MHM region on the chicken Z chromosome accumulate as non-coding RNA in the nucleus of female cells adjacent to the DMRT1 locus. | Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 20010101 |
[Effect of inhibitors of enzymatic DNA methylation on the formation of reproductive structures and carotenoid production in Neurospora crassa]. | Prikladnaia biokhimiia i mikrobiologiia 20010101 |
5-Azacytidine modulates the response of sensitive and multidrug-resistant K562 leukemic cells to cytostatic drugs. | Blood cells, molecules & diseases 20010101 |
Autoreactive murine Th1 and Th2 cells kill syngeneic macrophages and induce autoantibodies. | Lupus 20010101 |
6-azacytidine--compound with wide spectrum of antiviral activity. | Nucleosides, nucleotides & nucleic acids 20010101 |
Zidovudine (AZT) resistance in H9 cells due to decreased TK expression is associated with hypermethylation of TK gene. | Nucleosides, nucleotides & nucleic acids 20010101 |
Unnatural enantiomers of 5-azacytidine analogues: syntheses and enzymatic properties. | Nucleosides, nucleotides & nucleic acids 20010101 |
Demethylation by 5-aza-2'-deoxycytidine (5-azadC) of p16INK4A gene results in downregulation of vascular endothelial growth factor expression in human lung cancer cell lines. | Oncology research 20010101 |
Evaluation of pharmacological induction of fatty acid beta-oxidation in X-linked adrenoleukodystrophy. | Molecular genetics and metabolism 20010101 |
Altered hox gene expression and cellular pathogenesis of 5-aza-2'-deoxycytidine-induced murine hindlimb dysmorphogenesis. | Toxicologic pathology 20010101 |
Hematologic malignancies: an opportunity for targeted drug therapy. | The oncologist 20010101 |
Targeting hypomethylation of DNA to achieve cellular differentiation in myelodysplastic syndromes (MDS). | The oncologist 20010101 |
The involvement of photoregulated DNA methylation into a choice between sexual and asexual developmental pathways in Neurospora crassa. | Doklady. Biochemistry and biophysics 20010101 |
Genetic and cytological characterization of a developmental mutant of Aspergillus nidulans induced by 5-azacytidine. | Biological research 20010101 |
Induction/activation and detection of occult viral agents present in mammalian cells. | Developments in biologicals 20010101 |
[Sensitivity of E. coli and C. freundii strains to 5-azacytidine]. | Voprosy meditsinskoi khimii 20010101 |
Pharmacologic induction of fetal hemoglobin synthesis: cellular and molecular mechanisms. | Pediatric pathology & molecular medicine 20010101 |
Unnatural enantiomers of 5-azacytidine analogues: syntheses and enzymatic properties. | European journal of medicinal chemistry 20001101 |
Comparative effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on MCF-7, RL95-2, and LNCaP cells: role of target steroid hormones in cellular responsiveness to CYP1A1 induction. | Molecular cell biology research communications : MCBRC 20000901 |
Dihydro-5-azacytidine and cisplatin in the treatment of malignant mesothelioma: a phase II study by the Cancer and Leukemia Group B. | Cancer 19980415 |
Dihydro-5-azacytidine in malignant mesothelioma. A phase II trial demonstrating activity accompanied by cardiac toxicity. Cancer and Leukemia Group B. | Cancer 19970601 |
Pilot phase I-II study on 5-aza-2'-deoxycytidine (Decitabine) in patients with metastatic lung cancer. | Anti-cancer drugs 19970401 |
Inhibition of sandfly fever Sicilian virus (Phlebovirus) replication in vitro by antiviral compounds. | Research in virology 19970101 |
Rhabdomyolysis: an unusual complication of cytotoxic chemotherapy. | Medical oncology (Northwood, London, England) 19951201 |
Effect of 5-azacytidine on expression of the human DNA repair enzyme O6-methylguanine-DNA methyltransferase. | Carcinogenesis 19940401 |
Antiproliferative effects and DNA hypomethylation by 5-aza-2'-deoxycytidine in human neuroblastoma cell lines. | Anti-cancer drugs 19931201 |
A phase II study of 5,6-dihydro-5-azacytidine hydrochloride in disseminated malignant melanoma. | American journal of clinical oncology 19930601 |
Increased sensitivity of nontumorigenic fibroblasts expressing ras or myc oncogenes to malignant transformation induced by 5-aza-2'-deoxycytidine. | Cancer research 19910101 |
Comparative activities of several nucleoside analogs against duck hepatitis B virus in vitro. | Antimicrobial agents and chemotherapy 19900701 |
Comparison of the incidence of 5-azacytidine-induced exencephaly between MT/HokIdr and Slc:ICR mice. | Teratology 19900201 |
5-azacytidine and 5-azadeoxycytidine inhibit human immunodeficiency virus type 1 replication in vitro. | Antimicrobial agents and chemotherapy 19900201 |
Histological study of cell death in digital malformations induced by 5-azacytidine: suppressive effect of caffeine. | Teratology 19890201 |
Increased metallothionein gene expression in 5-aza-2'-deoxycytidine-induced resistance to cadmium cytotoxicity. | Chemico-biological interactions 19880101 |
Fetal hemoglobin gene activation in a phase II study of 5,6-dihydro-5-azacytidine for bronchogenic carcinoma. | Cancer research 19870801 |
Methylation differences in the murine P1450 and P3450 genes in wild-type and mutant hepatoma cell culture. | Biochemical pharmacology 19860701 |
Diaplacental carcinogenic effects of 5-azacytidine in NMRI-mice. | Cancer letters 19850501 |
Sequentially administered 5-azacitidine and amsacrine in refractory adult acute leukemia: a phase I-II trial of the Southeastern Cancer Study Group. | Cancer treatment reports 19850101 |
5-azacytidine potentiates initiation induced by carcinogens in rat liver. | Carcinogenesis 19850101 |
The tumorigenicity of 5-azacytidine in the male Fischer rat. | Carcinogenesis 19841201 |
Is there more than one critical lesion relevant for experimental liver carcinogenesis? | Toxicologic pathology 19840101 |
Developmental activation of the H-2K gene is correlated with an increase in DNA methylation. | Cell 19831201 |
5-azacytidine in refractory acute leukemia. | Oncology 19820101 |
5-Azacytidine and renal tubular dysfunction. | Blood 19810101 |
Cellular differentiation, cytidine analogs and DNA methylation. | Cell 19800501 |
Morphological correlates of behavioral abnormalities in experimental congenital brain damage. | Experimental neurology 19771001 |
Biological effects of 5-azacytidine in eukaryotes. | Oncology 19740101 |