Home Boronic acids [(1R)-1-{2-[(2,5-dichlorophenyl)formamido]acetamido}-3-methylbutyl]boronic acid

[(1R)-1-{2-[(2,5-dichlorophenyl)formamido]acetamido}-3-methylbutyl]boronic acid

CAS No.:
1072833-77-2
Catalog Number:
AG0037YJ
Molecular Formula:
C14H19BCl2N2O4
Molecular Weight:
361.0287
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
≥95%
1 week
United States
$105
- +
5mg
98%
1 week
United States
$207
- +
10mg
98%
1 week
United States
$257
- +
25mg
98%
1 week
United States
$507
- +
50mg
98%
1 week
United States
$807
- +
Product Description
Catalog Number:
AG0037YJ
Chemical Name:
[(1R)-1-{2-[(2,5-dichlorophenyl)formamido]acetamido}-3-methylbutyl]boronic acid
CAS Number:
1072833-77-2
Molecular Formula:
C14H19BCl2N2O4
Molecular Weight:
361.0287
MDL Number:
MFCD18251438
IUPAC Name:
[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid
InChI:
InChI=1S/C14H19BCl2N2O4/c1-8(2)5-12(15(22)23)19-13(20)7-18-14(21)10-6-9(16)3-4-11(10)17/h3-4,6,8,12,22-23H,5,7H2,1-2H3,(H,18,21)(H,19,20)/t12-/m0/s1
InChI Key:
MXAYKZJJDUDWDS-LBPRGKRZSA-N
SMILES:
OB([C@@H](NC(=O)CNC(=O)c1cc(Cl)ccc1Cl)CC(C)C)O
UNII:
71050168A2
Properties
Complexity:
412  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
360.081g/mol
Formal Charge:
0
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0
Molecular Weight:
361.026g/mol
Monoisotopic Mass:
360.081g/mol
Rotatable Bond Count:
7  
Topological Polar Surface Area:
98.7A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
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Ixazomib for the treatment of multiple myeloma. Expert opinion on investigational drugs 20150101
An evidence-based review of ixazomib citrate and its potential in the treatment of newly diagnosed multiple myeloma. OncoTargets and therapy 20140101
Identification of potent Yes1 kinase inhibitors using a library screening approach. Bioorganic & medicinal chemistry letters 20130801
Molecular mechanisms of acquired proteasome inhibitor resistance. Journal of medicinal chemistry 20121213
Evaluation of the proteasome inhibitor MLN9708 in preclinical models of human cancer. Cancer research 20100301
Bortezomib-mediated 26S proteasome inhibition causes cell-cycle arrest and induces apoptosis in CD-30+ anaplastic large cell lymphoma. Leukemia 20070401
Intracellular protein degradation: from a vague idea, through the lysosome and the ubiquitin-proteasome system, and onto human diseases and drug targeting (Nobel lecture). Angewandte Chemie (International ed. in English) 20050919
Properties