Home Nitriles 4,6-Diamino-2-(cyclopropylamino)pyrimidine-5-carbonitrile

4,6-Diamino-2-(cyclopropylamino)pyrimidine-5-carbonitrile

CAS No.:
112636-83-6
Catalog Number:
AG0037Y2
Molecular Formula:
C8H10N6
Molecular Weight:
190.2052
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Product Description
Catalog Number:
AG0037Y2
Chemical Name:
4,6-Diamino-2-(cyclopropylamino)pyrimidine-5-carbonitrile
CAS Number:
112636-83-6
Molecular Formula:
C8H10N6
Molecular Weight:
190.2052
MDL Number:
MFCD03095705
IUPAC Name:
4,6-diamino-2-(cyclopropylamino)pyrimidine-5-carbonitrile
InChI:
InChI=1S/C8H10N6/c9-3-5-6(10)13-8(14-7(5)11)12-4-1-2-4/h4H,1-2H2,(H5,10,11,12,13,14)
InChI Key:
PKTIFYGCWCQRSX-UHFFFAOYSA-N
SMILES:
N#Cc1c(N)nc(nc1N)NC1CC1
EC Number:
601-192-4
UNII:
DBC8O809S5
Properties
Complexity:
242  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
190.097g/mol
Formal Charge:
0
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
190.21g/mol
Monoisotopic Mass:
190.097g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
114A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.6  
Literature
Title Journal
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Suppressive effect of Siraitia grosvenorii extract on dicyclanil-promoted hepatocellular proliferative lesions in male mice. The Journal of toxicological sciences 20090201
Detection of oxidative DNA damage, cell proliferation and in vivo mutagenicity induced by dicyclanil, a non-genotoxic carcinogen, using gpt delta mice. Mutation research 20070901
Evaluating the insecticide resistance potential of eight Drosophila melanogaster cytochrome P450 genes by transgenic over-expression. Insect biochemistry and molecular biology 20070501
Cis-regulatory elements in the Accord retrotransposon result in tissue-specific expression of the Drosophila melanogaster insecticide resistance gene Cyp6g1. Genetics 20070301
Follow-up testing of rodent carcinogens not positive in the standard genotoxicity testing battery: IWGT workgroup report. Mutation research 20070203
Possible involvement of oxidative stress in dicyclanil-induced hepatocarcinogenesis in mice. Archives of toxicology 20061001
Gene expression analysis on the dicyclanil-induced hepatocellular tumors in mice. Toxicologic pathology 20060101
Molecular pathological analysis on the mechanism of liver carcinogenesis in dicyclanil-treated mice. Toxicology 20050227
Immuno-histochemical detection of MRPs in human lung cells in culture. Toxicology 20050227
Absence of in vivo genotoxicity and liver initiation activity of dicyclanil. The Journal of toxicological sciences 20030801
Degradation pathway of dicyclanil in water in the presence of titanium dioxide. Comparison with photolysis. Journal of agricultural and food chemistry 20020828
Properties