High sensitivity measurements of active oxysterols with automated filtration/filter backflush-solid phase extraction-liquid chromatography-mass spectrometry.

Journal of chromatography. A 20120914

Flip-flop of steroids in phospholipid bilayers: effects of the chemical structure on transbilayer diffusion.

Journal of the American Chemical Society 20120725

Highly potent binding and inverse agonist activity of bisphenol A derivatives for retinoid-related orphan nuclear receptor RORγ.

Toxicology letters 20120720

Oxysterols exert proinflammatory effects in placental trophoblasts via TLR4-dependent, cholesterol-sensitive activation of NF-κB.

Molecular human reproduction 20120701

Oxysterol sulfation by cytosolic sulfotransferase suppresses liver X receptor/sterol regulatory element binding protein-1c signaling pathway and reduces serum and hepatic lipids in mouse models of nonalcoholic fatty liver disease.

Metabolism: clinical and experimental 20120601

Regulation of the expression of interleukin-8 induced by 25-hydroxycholesterol in retinal pigment epithelium cells.

Acta ophthalmologica 20120601

Antisteroidogenic effects of hydrogen peroxide on rat granulosa cells.

Free radical research 20120601

Effect of triptolide on progesterone production from cultured rat granulosa cells.

Arzneimittel-Forschung 20120601

25-Hydroxycholesterol-3-sulfate attenuates inflammatory response via PPARγ signaling in human THP-1 macrophages.

American journal of physiology. Endocrinology and metabolism 20120401

Increased 25-hydroxycholesterol concentrations in the lungs of patients with chronic obstructive pulmonary disease.

Respirology (Carlton, Vic.) 20120401

Inhibition of cholesterol oxidation products (COPs) formation in emulsified porcine patties by phenolic-rich avocado (Persea americana Mill.) extracts.

Journal of agricultural and food chemistry 20120307

Comparative modeling of 25-hydroxycholesterol-7α-hydroxylase (CYP7B1): ligand binding and analysis of hereditary spastic paraplegia type 5 CYP7B1 mutations.

Journal of molecular modeling 20120201

Resveratrol increases the expression and activity of the low density lipoprotein receptor in hepatocytes by the proteolytic activation of the sterol regulatory element-binding proteins.

Atherosclerosis 20120201

HCV NS5A and NS5B enhance expression of human ceramide glucosyltransferase gene.

Virologica Sinica 20120201

Interferon regulator factor 1/retinoic inducible gene I (IRF1/RIG-I) axis mediates 25-hydroxycholesterol-induced interleukin-8 production in atherosclerosis.

Cardiovascular research 20120101

Steroidogenesis in amlodipine treated purified Leydig cells.

Toxicology and applied pharmacology 20120101

Inhibition of endothelial- and neuronal-type, but not inducible-type, nitric oxide synthase by the oxidized cholesterol metabolite secosterol aldehyde: Implications for vascular and neurodegenerative diseases.

Journal of clinical biochemistry and nutrition 20120101

TGFβ signaling and cardiovascular diseases.

International journal of biological sciences 20120101

Activation mobilizes the cholesterol in the late endosomes-lysosomes of Niemann Pick type C cells.

PloS one 20120101

Strain specific transcriptional response in Mycobacterium tuberculosis infected macrophages.

Cell communication and signaling : CCS 20120101

Progesterone synthesis in the nervous system: implications for myelination and myelin repair.

Frontiers in neuroscience 20120101

Central role of SREBP-2 in the pathogenesis of osteoarthritis.

PloS one 20120101

VEGF is involved in the increase of dermal microvascular permeability induced by tryptase.

ISRN dermatology 20120101

25-Hydroxycholesterol enhances cytokine release and Toll-like receptor 3 response in airway epithelial cells.

Respiratory research 20120101

The ATP-binding cassette transporter-2 (ABCA2) regulates cholesterol homeostasis and low-density lipoprotein receptor metabolism in N2a neuroblastoma cells.

Biochimica et biophysica acta 20111201

Linalool reduces the expression of 3-hydroxy-3-methylglutaryl CoA reductase via sterol regulatory element binding protein-2- and ubiquitin-dependent mechanisms.

FEBS letters 20111020

OSBP-related protein 7 interacts with GATE-16 and negatively regulates GS28 protein stability.

Experimental cell research 20111001

Natural products reveal cancer cell dependence on oxysterol-binding proteins.

Nature chemical biology 20110807

Cholesterol 25-hydroxylation activity of CYP3A.

Journal of lipid research 20110801

Still another activity by the highly promiscuous enzyme CYP3A4: 25-hydroxylation of cholesterol.

Journal of lipid research 20110801

Oxysterols direct B-cell migration through EBI2.

Nature 20110727

Synthesis and evaluation of diarylthiazole derivatives that inhibit activation of sterol regulatory element-binding proteins.

Journal of medicinal chemistry 20110714

Effect of high pressure processing on cholesterol oxidation products in vacuum packaged sliced dry-cured ham.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110601

Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

The Journal of biological chemistry 20110429

Lycopene prevention of oxysterol-induced proinflammatory cytokine cascade in human macrophages: inhibition of NF-κB nuclear binding and increase in PPARγ expression.

The Journal of nutritional biochemistry 20110301

25-Hydroxycholesterol increases the availability of cholesterol in phospholipid membranes.

Biophysical journal 20110216

Sulfation of 25-hydroxycholesterol by SULT2B1b decreases cellular lipids via the LXR/SREBP-1c signaling pathway in human aortic endothelial cells.

Atherosclerosis 20110201

Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors.

Placenta 20110201

(Sub)clinical cardiovascular disease is associated with increased bone loss and fracture risk; a systematic review of the association between cardiovascular disease and osteoporosis.

Arthritis research & therapy 20110101

The cholesterol metabolite 25-hydroxycholesterol activates estrogen receptor α-mediated signaling in cancer cells and in cardiomyocytes.

PloS one 20110101

Functional promoter polymorphisms govern differential expression of HMG-CoA reductase gene in mouse models of essential hypertension.

PloS one 20110101

Effects of the methanol extract of Basella alba L (Basellaceae) on steroid production in Leydig cells.

International journal of molecular sciences 20110101

Mechanisms of oxysterol-induced carcinogenesis.

Lipids in health and disease 20110101

Apelin attenuates the osteoblastic differentiation of vascular smooth muscle cells.

PloS one 20110101

Synthesis of the enantiomer of the oxysterol-antagonist LY295427.

Steroids 20110101

Coordinately regulated alternative splicing of genes involved in cholesterol biosynthesis and uptake.

PloS one 20110101

Contribution of cholesterol and oxysterols in the physiopathology of cataract: implication for the development of pharmacological treatments.

Journal of ophthalmology 20110101

OSBP-related protein 8 (ORP8) regulates plasma and liver tissue lipid levels and interacts with the nucleoporin Nup62.

PloS one 20110101

Antiviral drugs against hepatitis C virus.

Genetic vaccines and therapy 20110101

Comparative structural analysis of lipid binding START domains.

PloS one 20110101

Lipids, lipoproteins, and age-related macular degeneration.

Journal of lipids 20110101

Cholesterol-enriched diet causes age-related macular degeneration-like pathology in rabbit retina.

BMC ophthalmology 20110101

Hepatic n-3 polyunsaturated fatty acid depletion promotes steatosis and insulin resistance in mice: genomic analysis of cellular targets.

PloS one 20110101

Advanced glycation in macrophages induces intracellular accumulation of 7-ketocholesterol and total sterols by decreasing the expression of ABCA-1 and ABCG-1.

Lipids in health and disease 20110101

Sphingomyelin synthases regulate protein trafficking and secretion.

PloS one 20110101

A common polymorphism in NR1H2 (LXRbeta) is associated with preeclampsia.

BMC medical genetics 20110101

Camphene, a plant-derived monoterpene, reduces plasma cholesterol and triglycerides in hyperlipidemic rats independently of HMG-CoA reductase activity.

PloS one 20110101

Uropathogenic E. coli induce different immune response in testicular and peritoneal macrophages: implications for testicular immune privilege.

PloS one 20110101

Nifedipine protects INS-1 β-cell from high glucose-induced ER stress and apoptosis.

International journal of molecular sciences 20110101

The dynamin chemical inhibitor dynasore impairs cholesterol trafficking and sterol-sensitive genes transcription in human HeLa cells and macrophages.

PloS one 20110101

Inflammatory-induced hibernation in the fetus: priming of fetal sheep metabolism correlates with developmental brain injury.

PloS one 20110101

Activation of LDL receptor expression by small RNAs complementary to a noncoding transcript that overlaps the LDLR promoter.

Chemistry & biology 20101222

Effects and mechanisms of nonylphenol on corticosterone release in rat zona fasciculata-reticularis cells.

Toxicological sciences : an official journal of the Society of Toxicology 20101201

Identification of 5α, 6α-epoxycholesterol as a novel modulator of liver X receptor activity.

Molecular pharmacology 20101201

Editorial: 25-Hydroxycholesterol: a new life in immunology.

Journal of leukocyte biology 20101201

Molecular regulation of gonadotropin receptor expression: relationship to sterol metabolism.

Molecular and cellular endocrinology 20101125

Lipid rafts and redox regulation of cellular signaling in cholesterol induced atherosclerosis.

Current cardiology reviews 20101101

Effects of oxysterols on cell viability, inflammatory cytokines, VEGF, and reactive oxygen species production on human retinal cells: cytoprotective effects and prevention of VEGF secretion by resveratrol.

European journal of nutrition 20101001

Modulators of the hedgehog signaling pathway.

Bioorganic & medicinal chemistry 20100915

Placental ABCA1 and ABCG1 transporters efflux cholesterol and protect trophoblasts from oxysterol induced toxicity.

Biochimica et biophysica acta 20100901

Regulation of hepatocyte lipid metabolism and inflammatory response by 25-hydroxycholesterol and 25-hydroxycholesterol-3-sulfate.

Lipids 20100901

A second class of nuclear receptors for oxysterols: Regulation of RORalpha and RORgamma activity by 24S-hydroxycholesterol (cerebrosterol).

Biochimica et biophysica acta 20100801

Multivesicular body formation requires OSBP-related proteins and cholesterol.

PLoS genetics 20100801

Taking another look with fluorescence microscopy: image processing techniques in Langmuir monolayers for the twenty-first century.

Biochimica et biophysica acta 20100701

Overexpression of STARD3 in human monocyte/macrophages induces an anti-atherogenic lipid phenotype.

Clinical science (London, England : 1979) 20100622

Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from endoplasmic reticulum membranes into the cytosol through a subcellular compartment resembling lipid droplets.

The Journal of biological chemistry 20100618

Role of 8-iso-prostaglandin F2alpha and 25-hydroxycholesterol in the pathophysiology of endometriosis.

Fertility and sterility 20100601

Interaction of two oxysterols, 7-ketocholesterol and 25-hydroxycholesterol, with phosphatidylcholine and sphingomyelin in model membranes.

Chemistry and physics of lipids 20100601

Lipids-induced apoptosis is aggravated by acyl-coenzyme A: cholesterol acyltransferase inhibitor.

Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20100601

Analysis of the 22-NBD-cholesterol transfer between liposome membranes and its relation to the intermembrane exchange of 25-hydroxycholesterol.

Colloids and surfaces. B, Biointerfaces 20100501

Structural basis for hydroxycholesterols as natural ligands of orphan nuclear receptor RORgamma.

Molecular endocrinology (Baltimore, Md.) 20100501

Electrostatic interaction between oxysterol-binding protein and VAMP-associated protein A revealed by NMR and mutagenesis studies.

The Journal of biological chemistry 20100423

Marked accumulation of 27-hydroxycholesterol in SPG5 patients with hereditary spastic paresis.

Journal of lipid research 20100401

Low-density lipoprotein and oxysterols suppress the transcription of CTP: Phosphoethanolamine cytidylyltransferase in vitro.

Biochimica et biophysica acta 20100401

Regulation of hepatic gene expression by saturated fatty acids.

Prostaglandins, leukotrienes, and essential fatty acids 20100401

Oxysterol represses high-affinity IgE receptor-stimulated mast cell activation in Liver X receptor-dependent and -independent manners.

FEBS letters 20100319

Initial response of endothelial cells to acute stimulation with a lipid component: increase cyclooxygenase activity by induction of COX-2 through activation of tyrosine kinase.

Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20100201

Intramembrane glycine mediates multimerization of Insig-2, a requirement for sterol regulation in Chinese hamster ovary cells.

Journal of lipid research 20100101

Inhibition of carboxylesterase activity of THP1 monocytes/macrophages and recombinant human carboxylesterase 1 by oxysterols and fatty acids.

Biochimica et biophysica acta 20100101

Perfusion of veins at arterial pressure increases the expression of KLF5 and cell cycle genes in smooth muscle cells.

Biochemical and biophysical research communications 20100101

Metabolomic analyses of plasma reveals new insights into asphyxia and resuscitation in pigs.

PloS one 20100101

Alterations in the homeostasis of phospholipids and cholesterol by antitumor alkylphospholipids.

Lipids in health and disease 20100101

Oxpholipin 11D: an anti-inflammatory peptide that binds cholesterol and oxidized phospholipids.

PloS one 20100101

Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones.

Nutrition & metabolism 20100101

Effects of cholesterol and its 24S-OH and 25-OH oxysterols on choline acetyltransferase-positive neurons in brain slices.

Pharmacology 20100101

Fathead minnow steroidogenesis: in silico analyses reveals tradeoffs between nominal target efficacy and robustness to cross-talk.

BMC systems biology 20100101

Inhibition of stearoylCoA desaturase activity blocks cell cycle progression and induces programmed cell death in lung cancer cells.

PloS one 20100101

Fish oil supplementation reverses the effect of cholesterol on apoptotic gene expression in smooth muscle cells.

Lipids in health and disease 20100101

The oxysterol 27-hydroxycholesterol increases β-amyloid and oxidative stress in retinal pigment epithelial cells.

BMC ophthalmology 20100101

Cholesterol pathways affected by small molecules that decrease sterol levels in Niemann-Pick type C mutant cells.

PloS one 20100101

5-Androstene-3β,7β,17β-triol (β-AET) slows thermal injury induced osteopenia in mice: relation to aging and osteoporosis.

PloS one 20100101

25-Hydroxycholesterol exerts both a cox-2-dependent transient proliferative effect and cox-2-independent cytotoxic effect on bovine endothelial cells in a time- and cell-type-dependent manner.

Journal of angiogenesis research 20100101

Sitosterol reduces messenger RNA and protein expression levels of Niemann-Pick C1-like 1 in FHs 74 Int cells.

Nutrition research (New York, N.Y.) 20091201

Insulin-like growth factor-I-stimulated Akt phosphorylation and oligodendrocyte progenitor cell survival require cholesterol-enriched membranes.

Journal of neuroscience research 20091115

Apolipoprotein E on hepatitis C virion facilitates infection through interaction with low-density lipoprotein receptor.

Virology 20091110

LXR-activating oxysterols induce the expression of inflammatory markers in endothelial cells through LXR-independent mechanisms.

Atherosclerosis 20091101

Marked upregulation of cholesterol 25-hydroxylase expression by lipopolysaccharide.

Journal of lipid research 20091101

Liver X receptor regulates expression of MRP2 but not that of MDR1 and BCRP in the liver.

Biochimica et biophysica acta 20091101

Hepatocyte nuclear factor 1alpha plays a critical role in PCSK9 gene transcription and regulation by the natural hypocholesterolemic compound berberine.

The Journal of biological chemistry 20091016

Regulation of inhibin/activin expression in rat early antral follicles.

Molecular and cellular endocrinology 20091015

Effects of evodiamine and rutaecarpine on the secretion of corticosterone by zona fasciculata-reticularis cells in male rats.

Journal of cellular biochemistry 20091001

Oncogenic Ras, but not (V600E)B-RAF, protects from cholesterol depletion-induced apoptosis through the PI3K/AKT pathway in colorectal cancer cells.

Carcinogenesis 20091001

Oxysterol-induced rearrangement of the liquid-ordered phase: a possible link to Alzheimer's disease?

Journal of the American Chemical Society 20090902

Effects of cholesterol and nuclear hormone receptor agonists on the production of transforming growth factor-beta in macrophages.

Bulletin of experimental biology and medicine 20090901

Regulation of sterol regulatory element-binding transcription factor 1a by human chorionic gonadotropin and insulin in cultured rat theca-interstitial cells.

Biology of reproduction 20090801

OSBPL10, a novel candidate gene for high triglyceride trait in dyslipidemic Finnish subjects, regulates cellular lipid metabolism.

Journal of molecular medicine (Berlin, Germany) 20090801

OSBP-related protein 2 is a sterol receptor on lipid droplets that regulates the metabolism of neutral lipids.

Journal of lipid research 20090701

Stimulation of Akt poly-ubiquitination and proteasomal degradation in P388D1 cells by 7-ketocholesterol and 25-hydroxycholesterol.

Archives of biochemistry and biophysics 20090701

Ligand, receptor, and cell type-dependent regulation of ABCA1 and ABCG1 mRNA in prostate cancer epithelial cells.

Molecular cancer therapeutics 20090701

Structure of N-terminal domain of NPC1 reveals distinct subdomains for binding and transfer of cholesterol.

Cell 20090626

FGF-1 induces expression of LXRalpha and production of 25-hydroxycholesterol to upregulate the apoE gene in rat astrocytes.

Journal of lipid research 20090601

Desmosterol can replace cholesterol in sustaining cell proliferation and regulating the SREBP pathway in a sterol-Delta24-reductase-deficient cell line.

The Biochemical journal 20090513

25-hydroxycholesterol provokes oligodendrocyte cell line apoptosis and stimulates the secreted phospholipase A2 type IIA via LXR beta and PXR.

Journal of neurochemistry 20090501

Perturbations of membrane structure by cholesterol and cholesterol derivatives are determined by sterol orientation.

Journal of the American Chemical Society 20090408

7beta-Hydroxycholesterol and 25-hydroxycholesterol-induced interleukin-8 secretion involves a calcium-dependent activation of c-fos via the ERK1/2 signaling pathway in THP-1 cells: oxysterols-induced IL-8 secretion is calcium-dependent.

Cell biology and toxicology 20090401

Relationship of metabolic syndrome with incident aortic valve calcium and aortic valve calcium progression: the Multi-Ethnic Study of Atherosclerosis (MESA).

Diabetes 20090401

Regulation of the proprotein convertase subtilisin/kexin type 9 in intestinal epithelial cells.

American journal of physiology. Gastrointestinal and liver physiology 20090401

Direct effects, compensation, and recovery in female fathead minnows exposed to a model aromatase inhibitor.

Environmental health perspectives 20090401

Cholesterol-dependent anaplasma phagocytophilum exploits the low-density lipoprotein uptake pathway.

PLoS pathogens 20090301

Highly sensitive quantification of key regulatory oxysterols in biological samples by LC-ESI-MS/MS.

Journal of lipid research 20090201

Activation of hepatic lipase expression by oleic acid: possible involvement of USF1.

Nutrients 20090201

Side chain oxygenated cholesterol regulates cellular cholesterol homeostasis through direct sterol-membrane interactions.

The Journal of biological chemistry 20090116

Characterization of fluorescent sterol binding to purified human NPC1.

The Journal of biological chemistry 20090116

A facile synthesis of C-24 and C-25 oxysterols by in situ generated ethyl(trifluoromethyl)dioxirane.

Steroids 20090101

Transcriptional profiling of the effects of 25-hydroxycholesterol on human hepatocyte metabolism and the antiviral state it conveys against the hepatitis C virus.

BMC chemical biology 20090101

Sequential metabolism of 7-dehydrocholesterol to steroidal 5,7-dienes in adrenal glands and its biological implication in the skin.

PloS one 20090101

Identification of novel genes and pathways regulating SREBP transcriptional activity.

PloS one 20090101

[Activation of sterol regulatory element binding protein and its involvement in endothelial cell migration].

Zhonghua bing li xue za zhi = Chinese journal of pathology 20090101

Regulation of bile acid and cholesterol metabolism by PPARs.

PPAR research 20090101

Effect of oxysterol-induced apoptosis of vascular smooth muscle cells on experimental hypercholesterolemia.

Journal of biomedicine & biotechnology 20090101

Cross-talk between oxysterols and glucocorticoids: differential regulation of secreted phopholipase A2 and impact on oligodendrocyte death.

PloS one 20090101

Cholesterol homeostasis in two commonly used human prostate cancer cell-lines, LNCaP and PC-3.

PloS one 20090101

25-Hydroxycholesterol-3-sulfate regulates macrophage lipid metabolism via the LXR/SREBP-1 signaling pathway.

American journal of physiology. Endocrinology and metabolism 20081201

Primary hepatocytes as targets for hepatitis C virus replication.

Journal of viral hepatitis 20081201

Role of oxidative stress in adaptive responses in special reference to atherogenesis.

Journal of clinical biochemistry and nutrition 20081101

Liquid chromatography-tandem mass spectrometry determination of plasma 24S-hydroxycholesterol with chromatographic separation of 25-hydroxycholesterol.

Analytical biochemistry 20081001

CETP polymorphisms influence cholesterol metabolism but not Alzheimer's disease risk.

Brain research 20080926

SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth.

Cell metabolism 20080903

Activation of a caspase-3-independent mode of cell death associated with lysosomal destabilization in cultured human retinal pigment epithelial cells (ARPE-19) exposed to 7beta-hydroxycholesterol.

Current eye research 20080901

Cadmium chloride-induced disruption of testicular steroidogenesis in rainbow trout, Oncorhynchus mykiss.

Archives of environmental contamination and toxicology 20080701

OSBP negatively regulates ABCA1 protein stability.

The Journal of biological chemistry 20080627

25-hydroxycholesterol induces mitochondria-dependent apoptosis via activation of glycogen synthase kinase-3beta in PC12 cells.

Free radical research 20080601

Cholesterol supply and SREBPs modulate transcription of the Niemann-Pick C-1 gene in steroidogenic tissues.

Journal of lipid research 20080501

Ligand specificity and evolution of liver X receptors.

The Journal of steroid biochemistry and molecular biology 20080501

The N terminus controls sterol binding while the C terminus regulates the scaffolding function of OSBP.

The Journal of biological chemistry 20080321

Effectors of rapid homeostatic responses of endoplasmic reticulum cholesterol and 3-hydroxy-3-methylglutaryl-CoA reductase.

The Journal of biological chemistry 20080118

Purified NPC1 protein. I. Binding of cholesterol and oxysterols to a 1278-amino acid membrane protein.

The Journal of biological chemistry 20080111

OSBP-related protein 8 (ORP8) suppresses ABCA1 expression and cholesterol efflux from macrophages.

The Journal of biological chemistry 20080104

Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein.

Molecular neurodegeneration 20080101

[Effects of (22S,23S)- and (22R,23R)-3beta-hydroxy-22,23-oxido-5alpha-ergost-8(14)-en-15-ones on cholesteryl esters biosynthesis and acyl-CoA:cholesterol acyl transferase activity in Hep G2 cells].

Biomeditsinskaia khimiia 20080101

Different kinetics of cholesterol delivery to components of the cholesterol homeostatic machinery: implications for cholesterol trafficking to the endoplasmic reticulum.

Biochimica et biophysica acta 20080101

Taurine reduces the secretion of apolipoprotein B100 and lipids in HepG2 cells.

Lipids in health and disease 20080101

Liver x receptor: a novel therapeutic target.

Indian journal of pharmaceutical sciences 20080101

Liver X Receptor Agonists Inhibit the Phospholipid Regulatory Gene CTP: Phosphoethanolamine Cytidylyltransferase-Pcyt2.

Research letters in biochemistry 20080101

Biosynthesis of the regulatory oxysterol, 5-cholesten-3beta,25-diol 3-sulfate, in hepatocytes.

Journal of lipid research 20071201

Delta5 desaturase mRNA levels are increased by simvastatin via SREBP-1 at early stages, not via PPARalpha, in THP-1 cells.

European journal of pharmacology 20071001

27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen.

Nature medicine 20071001

Sulfated oxysterol, 25HC3S, is a potent regulator of lipid metabolism in human hepatocytes.

Biochemical and biophysical research communications 20070907

Ribonucleic acid binding protein-mediated regulation of luteinizing hormone receptor expression in granulosa cells: relationship to sterol metabolism.

Molecular endocrinology (Baltimore, Md.) 20070901

Amplification of the gene for SCAP, coupled with Insig-1 deficiency, confers sterol resistance in mutant Chinese hamster ovary cells.

Journal of lipid research 20070901

The mammalian oxysterol-binding protein-related proteins (ORPs) bind 25-hydroxycholesterol in an evolutionarily conserved pocket.

The Biochemical journal 20070801

Sterol regulatory element-binding protein-2- and liver X receptor-driven dual promoter regulation of hepatic ABC transporter A1 gene expression: mechanism underlying the unique response to cellular cholesterol status.

The Journal of biological chemistry 20070720

SREBP-1 regulates the expression of heme oxygenase 1 and the phosphatidylinositol-3 kinase regulatory subunit p55 gamma.

Journal of lipid research 20070701

Cholesterol oxidation is increased and PUFA decreased by frozen storage and grilling of Atlantic hake fillets (Merluccius hubbsi).

Lipids 20070701

Cytotoxic oxysterols induce caspase-independent myelin figure formation and caspase-dependent polar lipid accumulation.

Histochemistry and cell biology 20070601

Characterization of the sterol-binding domain of oxysterol-binding protein (OSBP)-related protein 4 reveals a novel role in vimentin organization.

Experimental cell research 20070415

Prevention of 7-ketocholesterol-induced mitochondrial damage and cell death by calmodulin inhibition.

Brain research 20070316

The low-density lipoprotein receptor plays a role in the infection of primary human hepatocytes by hepatitis C virus.

Journal of hepatology 20070301

25-Hydroxycholesterol, 7beta-hydroxycholesterol and 7-ketocholesterol upregulate interleukin-8 expression independently of Toll-like receptor 1, 2, 4 or 6 signalling in human macrophages.

Free radical research 20070301

Oxysterols induced inflammation and oxidation in primary porcine retinal pigment epithelial cells.

Current eye research 20070301

Regulation of human cytochrome P450 4F2 expression by sterol regulatory element-binding protein and lovastatin.

The Journal of biological chemistry 20070223

Up-regulation of skeletal muscle LIM protein 1 gene by 25-hydroxycholesterol may mediate morphological changes of rat aortic smooth muscle cells.

Life sciences 20070109

Cholesterol oxides as biomarkers of oxidative stress in type 1 and type 2 diabetes mellitus.

Diabetes/metabolism research and reviews 20070101

Modulation of human Niemann-Pick C1-like 1 gene expression by sterol: Role of sterol regulatory element binding protein 2.

American journal of physiology. Gastrointestinal and liver physiology 20070101

Biosynthetic capacity of rainbow trout (Oncorhynchus mykiss) interrenal tissue after cadmium exposure.

Archives of environmental contamination and toxicology 20070101

Evidence for the functional role of residues in the B'-C loop of baboon cytochrome P450 side-chain cleavage (CYP11A1) obtained by site-directed mutagenesis, kinetic analysis and homology modelling.

The Journal of steroid biochemistry and molecular biology 20070101

Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice.

Cell metabolism 20070101

Synthesis of the oxysterol, 24(S), 25-epoxycholesterol, parallels cholesterol production and may protect against cellular accumulation of newly-synthesized cholesterol.

Lipids in health and disease 20070101

Leptin stimulates endogenous cholesterol synthesis in human monocytes: New role of an old player in atherosclerotic plaque formation. Leptin-induced increase in cholesterol synthesis.

The international journal of biochemistry & cell biology 20070101

The immune response is involved in atherosclerotic plaque calcification: could the RANKL/RANK/OPG system be a marker of plaque instability?

Clinical & developmental immunology 20070101

A Chinese hamster ovarian cell line imports cholesterol by high density lipoprotein degradation.

The Journal of biological chemistry 20061215

Low cell cholesterol levels increase NFkappaB activity through a p38 MAPK-dependent mechanism.

Cellular signalling 20061201

Effects of crude adlay hull acetone extract on corticosterone release from rat zona fasciculata-reticularis cells.

Naunyn-Schmiedeberg's archives of pharmacology 20061101

Induction of apoptosis by 25-hydroxycholesterol in adult rat Leydig cells: protective effect of 17beta-estradiol.

Reproductive toxicology (Elmsford, N.Y.) 20061101

[Synthesis and structure-activity relationships of bioactive compounds using sterols].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20061101

Neuropeptides induced a pronounced and statin-sensitive dysregulation of mevalonate cycle in human monocytes of patients with hypercholesterolemia.

Neuropeptides 20061001

Oxysterol mixtures, in atheroma-relevant proportions, display synergistic and proapoptotic effects.

Free radical biology & medicine 20060915

ABCA1 mediates high-affinity uptake of 25-hydroxycholesterol by membrane vesicles and rapid efflux of oxysterol by intact cells.

American journal of physiology. Cell physiology 20060901

Bleomycin is a potent small-molecule inhibitor of hepatitis C virus replication.

Chembiochem : a European journal of chemical biology 20060901

25-Hydroxycholesterol has a dual effect on the proliferation of cultured rat astrocytes.

Neuropharmacology 20060801

RhoA and p38 MAPK mediate apoptosis induced by cellular cholesterol depletion.

Apoptosis : an international journal on programmed cell death 20060701

Sterol dependent regulation of human TM7SF2 gene expression: role of the encoded 3beta-hydroxysterol Delta14-reductase in human cholesterol biosynthesis.

Biochimica et biophysica acta 20060701

Seasonal variation in calcitropic hormones and bone accrual in puberty.

The British journal of nutrition 20060701

Regulation of cholesterol 25-hydroxylase expression by vitamin D3 metabolites in human prostate stromal cells.

Biochemical and biophysical research communications 20060630

Formation of cholesterol oxidation products in marinated foods during heating.

Journal of agricultural and food chemistry 20060628

Synthesis of ent-25-hydroxycholesterol.

Steroids 20060601

Localization of StarD5 cholesterol binding protein.

Journal of lipid research 20060601

HPLC method for quantification and characterization of cholesterol and its oxidation products in eggs.

Lipids 20060601

A critical role for the histidine residues in the catalytic function of acyl-CoA:cholesterol acyltransferase catalysis: evidence for catalytic difference between ACAT1 and ACAT2.

FEBS letters 20060515

Phase behavior of lipid monolayers containing DPPC and cholesterol analogs.

Biophysical journal 20060501

Identification of a novel sulfonated oxysterol, 5-cholesten-3beta,25-diol 3-sulfonate, in hepatocyte nuclei and mitochondria.

Journal of lipid research 20060501

Multiplexed flow cytometric analyses of pro- and anti-inflammatory cytokines in the culture media of oxysterol-treated human monocytic cells and in the sera of atherosclerotic patients.

Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Cloning and characterization of a cDNA encoding cholesterol side-chain cleavage cytochrome P450 (CYP11A1): tissue-distribution and changes in the transcript abundance in ovarian tissue of Japanese eel, Anguilla japonica, during artificially induced sexual development.

The Journal of steroid biochemistry and molecular biology 20060501

Cholesterol, LDL, and 25-hydroxycholesterol regulate expression of the steroidogenic acute regulatory protein in microvascular endothelial cell line (bEnd.3).

Biochemical and biophysical research communications 20060421

Apoptotic effects of 25-hydroxycholesterol in immature rat Sertoli cells: prevention by 17beta-estradiol.

Reproductive toxicology (Elmsford, N.Y.) 20060401

Discovery and optimization of a novel series of liver X receptor-alpha agonists.

Bioorganic & medicinal chemistry letters 20060315

Analysis of oxysterols by electrospray tandem mass spectrometry.

Journal of the American Society for Mass Spectrometry 20060301

Coxiella burnetii inhabits a cholesterol-rich vacuole and influences cellular cholesterol metabolism.

Cellular microbiology 20060301

The influence of cholesterol and lipid metabolism on host cell structure and hepatitis C virus replication.

Biochemistry and cell biology = Biochimie et biologie cellulaire 20060201

Expression and localization of PCSK9 in rat hepatic cells.

Biochemistry and cell biology = Biochimie et biologie cellulaire 20060201

Effects of hydroxysterols and atorvastatin on lipopolysaccharide-induced secretion of tumor necrosis factor and interleukin-10 by mouse macrophages.

Bulletin of experimental biology and medicine 20060201

Physiologic interactions between macrophages and Leydig cells.

Experimental biology and medicine (Maywood, N.J.) 20060101

Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake.

Cell metabolism 20060101

Targeted silencing of Jab1/Csn5 in human cells downregulates SCF activity through reduction of F-box protein levels.

BMC biochemistry 20060101

Receptor Ck-dependent signaling regulates hTERT gene transcription.

BMC cell biology 20060101

Drug-induced activation of SREBP-controlled lipogenic gene expression in CNS-related cell lines: marked differences between various antipsychotic drugs.

BMC neuroscience 20060101

Oxidized LDL, a critical factor in atherogenesis.

Cardiovascular research 20051201

Combined effect of 25-hydroxycholesterol and IL-1beta on IL-8 production in human colon carcinoma cell line (Caco-2).

Inflammation 20051201

Regulation of adiponectin receptor 1 in human hepatocytes by agonists of nuclear receptors.

Biochemical and biophysical research communications 20050902

Sterol structure determines miscibility versus melting transitions in lipid vesicles.

Biophysical journal 20050901

Structural mechanism for sterol sensing and transport by OSBP-related proteins.

Nature 20050901

Human StarD5, a cytosolic StAR-related lipid binding protein.

Journal of lipid research 20050801

Is C-26 hydroxylation an evolutionarily conserved steroid inactivation mechanism?

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050801

Inhibition of cholesterol biosynthesis by 25-hydroxycholesterol is independent of OSBP.

Genes to cells : devoted to molecular & cellular mechanisms 20050801

Insig required for sterol-mediated inhibition of Scap/SREBP binding to COPII proteins in vitro.

The Journal of biological chemistry 20050715

Isolation of sterol-resistant Chinese hamster ovary cells with genetic deficiencies in both Insig-1 and Insig-2.

The Journal of biological chemistry 20050701

Cholesterol modulation of the expression of mitochondrial aconitase in human prostatic carcinoma cells.

The Chinese journal of physiology 20050630

Cholesterol modulates human intestinal sodium-dependent bile acid transporter.

American journal of physiology. Gastrointestinal and liver physiology 20050501

Tocotrienols reduce 25-hydroxycholesterol-induced monocyte-endothelial cell interaction by inhibiting the surface expression of adhesion molecules.

Atherosclerosis 20050501

In vivo and in vitro exposures of carp and carp tissues to graded concentrations of endocrine disrupting chemicals.

Annals of the New York Academy of Sciences 20050401

A new LC/APCI-MS method for the determination of cholesterol oxidation products in food.

Journal of chromatography. A 20050304

Comparison of the cytotoxic, pro-oxidant and pro-inflammatory characteristics of different oxysterols.

Cell biology and toxicology 20050301

Post-transcriptional regulation of apoC-I synthesis and secretion in human HepG2 cells.

Atherosclerosis 20050201

Differential effects of mixtures of cholesterol oxidation products on bovine aortic endothelial cells and human monocytic U937 cells.

International journal of toxicology 20050101

Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs.

The Journal of biological chemistry 20041210

Translocation of phospholipase A2 to membranes by oxidized LDL and hydroxyoctadecadienoic acid to contribute to cholesteryl ester formation.

Biochimica et biophysica acta 20041108

Effects of 25-hydroxycholesterol on cholesterol esterification and sterol regulatory element-binding protein processing are dissociable: implications for cholesterol movement to the regulatory pool in the endoplasmic reticulum.

The Journal of biological chemistry 20041105

The influence of the amino acid substitution I98K on the catalytic activity of baboon cytochrome P450 side-chain cleavage (CYP11A1).

Endocrine research 20041101

Role for sterol regulatory element-binding protein in activation of endothelial cells by phospholipid oxidation products.

Circulation research 20041015

Vascular endothelial growth factor activation of sterol regulatory element binding protein: a potential role in angiogenesis.

Circulation research 20040903

Platelet-derived growth factor stimulates membrane lipid synthesis through activation of phosphatidylinositol 3-kinase and sterol regulatory element-binding proteins.

The Journal of biological chemistry 20040820

Mechanisms of cholesterol and sterol regulatory element binding protein regulation of the sterol 12alpha-hydroxylase gene (CYP8B1).

Biochemical and biophysical research communications 20040806

Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia.

Arteriosclerosis, thrombosis, and vascular biology 20040801

25-hydroxycholesterol acts in the Golgi compartment to induce degradation of tyrosinase.

Pigment cell research 20040801

The effect of LXR activators on AP-1 proteins in keratinocytes.

The Journal of investigative dermatology 20040701

Cell-based screen of HMG-CoA reductase inhibitors and expression regulators using LC-MS.

Analytical biochemistry 20040601

Rat cytochrome P450C24 (CYP24A1) and the role of F249 in substrate binding and catalytic activity.

Archives of biochemistry and biophysics 20040515

Sterol regulation of scavenger receptor class B type I in macrophages.

Journal of lipid research 20040501

Signaling pathway of magnolol-stimulated lipolysis in sterol ester-loaded 3T3-L1 preadipocyes.

Journal of cellular biochemistry 20040401

Oxysterols regulate expression of the steroidogenic acute regulatory protein.

Journal of molecular endocrinology 20040401

Effect of LPS on basal and induced apo E secretion by 25-OH chol and 9cRA in differentiated CaCo-2.

Journal of cellular biochemistry 20040301

Apomine, a novel hypocholesterolemic agent, accelerates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and stimulates low density lipoprotein receptor activity.

The Journal of biological chemistry 20040220

Peroxisome proliferator-activated receptor alpha (PPARalpha) activators induce hepatic farnesyl diphosphate synthase gene expression in rodents.

The Journal of steroid biochemistry and molecular biology 20040201

AKT/protein kinase B regulation of BCL family members during oxysterol-induced apoptosis.

The Journal of biological chemistry 20040109

CYP3A induction by liver x receptor ligands in primary cultured rat and mouse hepatocytes is mediated by the pregnane X receptor.

Drug metabolism and disposition: the biological fate of chemicals 20040101

NFY interacts with the promoter region of two genes involved in the rat peroxisomal fatty acid beta-oxidation: the multifunctional protein type 1 and the 3-ketoacyl-CoA B thiolase.

Lipids in health and disease 20040101

Analysis of cholesterol oxidation products in biological samples.

Journal of AOAC International 20040101

Inhibitory effects of red wine extracts on endothelial-dependent adhesive interactions with monocytes induced by oxysterols.

Biological research 20040101

Antisteroidogenic actions of hydrogen peroxide on rat Leydig cells.

Journal of cellular biochemistry 20031215

Cholesterol oxides mediated changes in cytoskeletal organisation involves Rho GTPases.

Experimental cell research 20031210

Steroid structural requirements for stabilizing or disrupting lipid domains.

Biochemistry 20031209

Oxysterol and 9-cis-retinoic acid stimulate the group IIA secretory phospholipase A2 gene in rat smooth-muscle cells.

The Biochemical journal 20031201

Effects of dehydroepiandrosterone on corticosterone release in rat zona fasciculata-reticularis cells.

Naunyn-Schmiedeberg's archives of pharmacology 20031201

Identification of natural ligands of retinoic acid receptor-related orphan receptor alpha ligand-binding domain expressed in Sf9 cells--a mass spectrometry approach.

Analytical biochemistry 20031201

In vivo implants of beta-sitosterol cause reductions of reactive cholesterol pools in mitochondria isolated from gonads of male goldfish (Carassius auratus).

General and comparative endocrinology 20031201

Clofibrate, a peroxisome-proliferator, enhances reverse cholesterol transport through cytochrome P450 activation and oxysterol generation.

The Tohoku journal of experimental medicine 20031201

Serum ferritin concentration is associated with plasma levels of cholesterol oxidation products in man.

Free radical biology & medicine 20031015

7-ketocholesterol stimulates differentiation of lens epithelial cells.

Molecular vision 20031006

Origin of oxysterols in hepatic bile of patients with biliary infection.

The American journal of gastroenterology 20031001

Hypoxia increases 25-hydroxycholesterol-induced interleukin-8 protein secretion in human macrophages.

Atherosclerosis 20031001

Direct effect of propylthiouracil on progesterone release in rat granulosa cells.

British journal of pharmacology 20030802

On the substrate specificity of human CYP27A1: implications for bile acid and cholestanol formation.

Journal of lipid research 20030801

Regulation of PPAR-gamma gene in human promyelocytic HL-60 cell line.

Leukemia research 20030801

Involvement of the SREBP pathway in the mode of action of androgens in sebaceous glands in vivo.

Experimental dermatology 20030801

NPC1 and NPC2 regulate cellular cholesterol homeostasis through generation of low density lipoprotein cholesterol-derived oxysterols.

The Journal of biological chemistry 20030711

Oxysterols suppress constitutive fibrinogen expression.

Thrombosis and haemostasis 20030701

Sterol-mediated regulation of hormone-sensitive lipase in 3T3-L1 adipocytes.

Lipids 20030701

Oxysterol-induced toxicity in R28 and ARPE-19 cells.

Neurochemical research 20030601

PPAR agonists protect mesangial cells from interleukin 1beta-induced intracellular lipid accumulation by activating the ABCA1 cholesterol efflux pathway.

Journal of the American Society of Nephrology : JASN 20030301

Seasonal alterations in adrenocortical cell function associated with stress-responsiveness and sex in the eastern fence lizard (Sceloporus undulatus).

Hormones and behavior 20030301

Effects of dioxin (2,3,7,8-TCDD) and PCDDs/PCDFs congeners mixture on steroidogenesis in human placenta tissue culture.

Endocrine regulations 20030301

Regulation of isoprenoid/cholesterol biosynthesis in cells from mevalonate kinase-deficient patients.

The Journal of biological chemistry 20030221

Oxysterols induce apoptosis and accumulation of cell cycle at G(2)/M phase in the human monocytic THP-1 cell line.

Life sciences 20030207

Liver X receptor activators display anti-inflammatory activity in irritant and allergic contact dermatitis models: liver-X-receptor-specific inhibition of inflammation and primary cytokine production.

The Journal of investigative dermatology 20030201

Cholesterol cell content modulates GTPase activity of G proteins in GH4C1 cell membranes.

Cellular signalling 20030101

Toxicity of cholesterol oxidation products to Caco-2 and HepG2 cells: modulatory effects of alpha- and gamma-tocopherol.

Journal of applied toxicology : JAT 20030101

Cholesterol transport and steroidogenesis by the corpus luteum.

Reproductive biology and endocrinology : RB&E 20030101

On the rate of translocation in vitro and kinetics in vivo of the major oxysterols in human circulation: critical importance of the position of the oxygen function.

Journal of lipid research 20021201

Testosterone regulates 25-hydroxycholesterol production in testicular macrophages.

Biology of reproduction 20021101

Bile acids enhance low density lipoprotein receptor gene expression via a MAPK cascade-mediated stabilization of mRNA.

The Journal of biological chemistry 20021004

Dietary cholesterol-oxidation products accumulate in serum and liver in apolipoprotein E-deficient mice, but do not accelerate atherosclerosis.

The British journal of nutrition 20021001

Inhibition of testosterone production by propylthiouracil in rat Leydig cells.

Biology of reproduction 20020801

Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism.

Molecular cell 20020801

Effect of oxysterols on hematopoietic progenitor cells.

Experimental hematology 20020701

7-Ketocholesterol and staurosporine induce opposite changes in intracellular pH, associated with distinct types of cell death in ECV304 cells.

Archives of biochemistry and biophysics 20020615

Dietary cholesterol fails to stimulate the human cholesterol 7alpha-hydroxylase gene (CYP7A1) in transgenic mice.

The Journal of biological chemistry 20020607

Human organic anion transporting polypeptide 8 promoter is transactivated by the farnesoid X receptor/bile acid receptor.

Gastroenterology 20020601

Characterization of the estrogenic response to genistein in Japanese medaka (Oryzias latipes).

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020601

Induction of hepatic inducible nitric oxide synthase by cholesterol in vivo and in vitro.

Experimental & molecular medicine 20020531

25-hydroxycholesterol is produced by testicular macrophages during the early postnatal period and influences differentiation of Leydig cells in vitro.

Biology of reproduction 20020501

25R,26-Hydroxycholesterol revisited: synthesis, metabolism, and biologic roles.

Journal of lipid research 20020501

The cDNA cloning and tissue expression of the cytochrome P450scc from Syrian hamster (Mesocricetus auratus).

General and comparative endocrinology 20020501

Cholesterol, hydroxycholesterols, and bile acids.

Biochemical and biophysical research communications 20020419

Modulation of goldfish testicular testosterone production in vitro by tumor necrosis factor alpha, interleukin-1beta, and macrophage conditioned media.

The Journal of experimental zoology 20020401

Lymphatic transport of dietary cholesterol oxidation products, cholesterol and triacylglycerols in rats.

Bioscience, biotechnology, and biochemistry 20020401

A Link between cholesterol levels and phenobarbital induction of cytochromes P450.

Biochemical and biophysical research communications 20020222

Oxysterol-binding-protein (OSBP)-related protein 4 binds 25-hydroxycholesterol and interacts with vimentin intermediate filaments.

The Biochemical journal 20020201

Cellular antioxidant effects of atorvastatin in vitro and in vivo.

Arteriosclerosis, thrombosis, and vascular biology 20020201

Scavenger receptor class B type I is expressed in cultured keratinocytes and epidermis. Regulation in response to changes in cholesterol homeostasis and barrier requirements.

The Journal of biological chemistry 20020125

Dissociation of apoptosis induction and CD36 upregulation by enzymatically modified low-density lipoprotein in monocytic cells.

Biochemical and biophysical research communications 20020125

Induction of monocyte differentiation and foam cell formation in vitro by 7-ketocholesterol.

Journal of lipid research 20020101

Oxysterols induce interleukin-1beta production in human macrophages.

European journal of clinical investigation 20020101

Selective effect of cholesterylphosphoserine on intracellular cholesterol transport.

Lipids 20020101

Green tea catechins decrease apolipoprotein B-100 secretion from HepG2 cells.

Molecular and cellular biochemistry 20020101

The effect of Puerariae radix on lipoprotein metabolism in liver and intestinal cells.

BMC complementary and alternative medicine 20020101

Adrenodoxin-cytochrome P450scc interaction as revealed by EPR spectroscopy: comparison with the putidaredoxin-cytochrome P450cam system.

Journal of biochemistry 20011201

The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols.

The Journal of biological chemistry 20011130

Acid sphingomyelinase-deficient macrophages have defective cholesterol trafficking and efflux.

The Journal of biological chemistry 20011130

7-Ketocholesterol forms crystalline domains in model membranes and murine aortic smooth muscle cells.

Atherosclerosis 20011101

Growth modulation of low density lipoprotein receptor sterol sensitivity in cultured human fibroblasts.

Lipids 20011101

Molecular cloning and structural analysis of human sterol C5 desaturase.

Biochimica et biophysica acta 20011031

Inhibition of the mitogen activated protein kinase, p38 alpha, prevents proinflammatory cytokine induction by human adherent mononuclear leukocytes in response to lipid loading.

Atherosclerosis 20011001

Arachidonate metabolism and the signaling pathway of induction of apoptosis by oxidized LDL/oxysterol.

Journal of lipid research 20011001

Regulation of sterol regulatory element-binding proteins by cholesterol flux in CaCo-2 cells.

Journal of lipid research 20011001

25-hydroxycholesterol induces lipopolysaccharide-tolerance and decreases a lipopolysaccharide-induced TNF-alpha secretion in macrophages.

Atherosclerosis 20010901

Binding and uptake of chylomicron remnants by primary and THP-1 human monocyte-derived macrophages: determination of binding proteins.

Clinical science (London, England : 1979) 20010801

[Studies on the mechanism of arterial in vitro calcification].

Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20010801

Woc (without children) gene control of ecdysone biosynthesis in Drosophila melanogaster.

Molecular and cellular endocrinology 20010705

Concerted transcriptional activation of the low density lipoprotein receptor gene by insulin and luteinizing hormone in cultured porcine granulosa-luteal cells: possible convergence of protein kinase a, phosphatidylinositol 3-kinase, and mitogen-activated protein kinase signaling pathways.

Endocrinology 20010701

Fatty acid modifications and cholesterol oxidation in pork loin during frying at different temperatures.

Journal of food protection 20010701

Neurosteroid hydroxylase CYP7B: vivid reporter activity in dentate gyrus of gene-targeted mice and abolition of a widespread pathway of steroid and oxysterol hydroxylation.

The Journal of biological chemistry 20010629

Plant sterols regulate rat vascular smooth muscle cell growth and prostacyclin release in culture.

Prostaglandins, leukotrienes, and essential fatty acids 20010601

Stimulatory effect of lactate on testosterone production by rat Leydig cells.

Journal of cellular biochemistry 20010601

Novel members of the human oxysterol-binding protein family bind phospholipids and regulate vesicle transport.

The Journal of biological chemistry 20010525

Selective distribution of oxysterols in atherosclerotic lesions and human plasma lipoproteins.

Free radical research 20010501

An oxidized derivative of cholesterol increases the release of soluble vascular cell adhesion molecule-1 from human umbilical vein endothelial cells in culture.

Biochimica et biophysica acta 20010430

Differential modulation of ACAT1 and ACAT2 transcription and activity by long chain free fatty acids in cultured cells.

Biochemistry 20010417

cyp7b1 catalyses the 7alpha-hydroxylation of dehydroepiandrosterone and 25-hydroxycholesterol in rat prostate.

The Biochemical journal 20010415

Coronary atherosclerosis and oxidative stress as reflected by autoantibodies against oxidized low-density lipoprotein and oxysterols.

Atherosclerosis 20010401

Key regulatory oxysterols in liver: analysis as delta4-3-ketone derivatives by HPLC and response to physiological perturbations.

Journal of lipid research 20010401

Direct inhibitory effect of digitalis on progesterone release from rat granulosa cells.

British journal of pharmacology 20010401

Pharmacophore analysis of the nuclear oxysterol receptor LXRalpha.

Journal of medicinal chemistry 20010315

Fas/Fas ligand-mediated death pathway is involved in oxLDL-induced apoptosis in vascular smooth muscle cells.

American journal of physiology. Cell physiology 20010301

Production of 25-hydroxycholesterol by testicular macrophages and its effects on Leydig cells.

Biology of reproduction 20010301

Control of apolipoprotein E secretion in the human hepatoma cell line KYN-2.

Cell biochemistry and function 20010301

Cholesterol biosynthesis from lanosterol: molecular cloning, chromosomal localization, functional expression and liver-specific gene regulation of rat sterol delta8-isomerase, a cholesterogenic enzyme with multiple functions.

The Biochemical journal 20010201

Mechanism of action of noradrenaline on secretion of progesterone and oxytocin by the bovine corpus luteum in vitro.

Acta veterinaria Hungarica 20010101

Comparative study of the cytotoxicity and apoptosis-inducing potential of commonly occurring oxysterols.

Cell biology and toxicology 20010101

Control of apolipoprotein E secretion by 25-hydroxycholesterol and proinflammatory cytokines in the human astrocytoma cell line CCF-STTG1.

Cell biology and toxicology 20010101

Peroxisome proliferator-activated receptor agonists prevent 25-OH-cholesterol induced c-jun activation and cell death.

BMC pharmacology 20010101

Oxysterol 7 alpha-hydroxylase activity by cholesterol 7 alpha-hydroxylase (CYP7A).

The Journal of biological chemistry 20001103

Expression cloning of an oxysterol 7alpha-hydroxylase selective for 24-hydroxycholesterol.

The Journal of biological chemistry 20000602

The mevalonate/isoprenoid pathway inhibitor apomine (SR-45023A) is antiproliferative and induces apoptosis similar to farnesol.

Biochemical and biophysical research communications 20000402

Down-regulation of mammalian 3-hydroxy-3-methylglutaryl coenzyme A reductase activity with highly purified liposomal cholesterol.

European journal of biochemistry 19991201

Oxysterol regulation of steroidogenic acute regulatory protein gene expression. Structural specificity and transcriptional and posttranscriptional actions.

The Journal of biological chemistry 19981113

Oxysterols, but not cholesterol, inhibit human immunodeficiency virus replication in vitro.

Antiviral chemistry & chemotherapy 19981101

Meiosis-activating sterol promotes resumption of meiosis in mouse oocytes cultured in vitro in contrast to related oxysterols.

Biology of reproduction 19980501

Activation of the orphan nuclear receptor steroidogenic factor 1 by oxysterols.

Proceedings of the National Academy of Sciences of the United States of America 19970513

Studies on the relationships between 7 alpha-hydroxylation and the ability of 25- and 27-hydroxycholesterol to suppress the activity of HMG-CoA reductase.

Biochimica et biophysica acta 19970218

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway.

The Journal of biological chemistry 19970207

Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages.

The Journal of clinical investigation 19960115

Effects of 26-aminocholesterol, 27-hydroxycholesterol, and 25-hydroxycholesterol on proliferation and cholesterol homeostasis in arterial myocytes.

Arteriosclerosis, thrombosis, and vascular biology 19950301

Structural specificity in the suppression of HMG-CoA reductase in human fibroblasts by intermediates in bile acid biosynthesis.

Journal of lipid research 19950201

7 alpha hydroxylation of 25-hydroxycholesterol in liver microsomes. Evidence that the enzyme involved is different from cholesterol 7 alpha-hydroxylase.

European journal of biochemistry 19940901

Atherosclerosis and sterol 27-hydroxylase: evidence for a role of this enzyme in elimination of cholesterol from human macrophages.

Proceedings of the National Academy of Sciences of the United States of America 19940830

24-, 25- and 27-hydroxylation of cholesterol by a purified preparation of 27-hydroxylase from pig liver.

Biochimica et biophysica acta 19930224