Home Other Building Blocks (7aS,13aR,13bR,13cS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one

(7aS,13aR,13bR,13cS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one

CAS No.:
519-02-8
Catalog Number:
AG0037PX
Molecular Formula:
C15H24N2O
Molecular Weight:
248.3639
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
98%(GC)
In Stock USA
United States
$60
- +
100mg
98%(GC)
In Stock USA
United States
$143
- +
250mg
98%(GC)
In Stock USA
United States
$282
- +
500mg
98%(GC)
In Stock USA
United States
$483
- +
1g
98%(GC)
In Stock USA
United States
$890
- +
Product Description
Catalog Number:
AG0037PX
Chemical Name:
(7aS,13aR,13bR,13cS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one
CAS Number:
519-02-8
Molecular Formula:
C15H24N2O
Molecular Weight:
248.3639
MDL Number:
MFCD00210527
IUPAC Name:
(1R,2R,9S,17S)-7,13-diazatetracyclo[7.7.1.02,7.013,17]heptadecan-6-one
InChI:
InChI=1S/C15H24N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15-/m0/s1
InChI Key:
ZSBXGIUJOOQZMP-JLNYLFASSA-N
SMILES:
O=C1CCC[C@H]2N1C[C@@H]1CCCN3[C@@H]1[C@@H]2CCC3
EC Number:
610-750-6
UNII:
N390W430AC
NSC Number:
146051
Properties
Complexity:
356  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
0
Exact Mass:
248.189g/mol
Formal Charge:
0
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
248.37g/mol
Monoisotopic Mass:
248.189g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
23.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.6  
Literature
Title Journal
Matrine compromises mouse sperm functions by a [Ca(2+)]i-related mechanism. Reproductive toxicology (Elmsford, N.Y.) 20160401
Arsenic trioxide-enhanced, matrine-induced apoptosis in multiple myeloma cell lines. Planta medica 20130601
Arsenic trioxide-induced hERG K(+) channel deficiency can be rescued by matrine and oxymatrine through up-regulating transcription factor Sp1 expression. Biochemical pharmacology 20130101
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine. Bioorganic & medicinal chemistry 20121115
Effects of the Chinese medicine matrine on experimental C. parvum infection in BALB/c mice and MDBK cells. Parasitology research 20121001
[Effects of matrine on the proliferation and apoptosis of human rhabdomyosarcoma RD cells]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20121001
Matrine modulates HSC70 levels and rescues ΔF508-CFTR. Journal of cellular physiology 20120901
Post-expansile hydrogel foam aerosol of PG-liposomes: a novel delivery system for vaginal drug delivery applications. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120830
Antiviral effect of matrine against human enterovirus 71. Molecules (Basel, Switzerland) 20120829
Regulation of endothelial nitric oxide synthase and asymmetric dimethylarginine by matrine attenuates isoproterenol-induced acute myocardial injury in rats. The Journal of pharmacy and pharmacology 20120801
Matrine- and oxymatrine-imprinted monodisperse polymers prepared by precipitation polymerization and their applications for the selective extraction of matrine-type alkaloids from Sophora flavescens Aiton. Journal of chromatography. A 20120727
Preparation and characterization of magnetic alginate-chitosan hydrogel beads loaded matrine. Drug development and industrial pharmacy 20120701
Neuroprotective effect of early and short-time applying sophoridine in pMCAO rat brain: down-regulated TRAF6 and up-regulated p-ERK1/2 expression, ameliorated brain infaction and edema. Brain research bulletin 20120701
Comprehensive two-dimensional HepG2/cell membrane chromatography/monolithic column/time-of-flight mass spectrometry system for screening anti-tumor components from herbal medicines. Journal of chromatography. A 20120615
Synthesis, characterization and in vitro anti-tumor activities of matrine derivatives. Bioorganic & medicinal chemistry letters 20120615
The influence of intraoperative pleural perfusion with matrine-cisplatin or cisplatin on stromal cell-derived factor-1 in non-small cell lung cancer patients with subclinical pleural metastasis. Medical oncology (Northwood, London, England) 20120601
Effects of matrine on proliferation and apoptosis of cultured retinoblastoma cells. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20120601
Effects of matrine on proliferation and apoptosis in gallbladder carcinoma cells (GBC-SD). Phytotherapy research : PTR 20120601
Direct protection of neurons and astrocytes by matrine via inhibition of the NF-κB signaling pathway contributes to neuroprotection against focal cerebral ischemia. Brain research 20120515
Inhibition of matrine against gastric cancer cell line MNK45 growth and its anti-tumor mechanism. Molecular biology reports 20120501
Matrine inhibits proliferation and induces apoptosis of the androgen‑independent prostate cancer cell line PC-3. Molecular medicine reports 20120301
Matrine induces caspase-dependent apoptosis in human osteosarcoma cells in vitro and in vivo through the upregulation of Bax and Fas/FasL and downregulation of Bcl-2. Cancer chemotherapy and pharmacology 20120201
Matrine inhibits disturbed flow-enhanced migration via downregulation of ERK1/2-MLCK signaling vascular smooth muscle cells. Annals of vascular surgery 20120201
Oxymatrinium tetra-chloridoferrate(III). Acta crystallographica. Section E, Structure reports online 20120201
Subcritical water extraction of alkaloids in Sophora flavescens Ait. and determination by capillary electrophoresis with field-amplified sample stacking. Journal of pharmaceutical and biomedical analysis 20120125
Effects and mechanism characterization of ionic liquids as mobile phase additives for the separation of matrine-type alkaloids by liquid chromatography. Journal of pharmaceutical and biomedical analysis 20120125
Anti-inflammatory effects of active constituents extracted from Chinese medicinal herbs against Propionibacterium acnes. Natural product research 20120101
Selective extraction and separation of oxymatrine from Sophora flavescens Ait. extract by silica-confined ionic liquid. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120101
Matrine inhibits pacing induced atrial fibrillation by modulating I(KM3) and I(Ca-L). International journal of biological sciences 20120101
Impact of the herbal medicine Sophora flavescens on the oral pharmacokinetics of indinavir in rats: the involvement of CYP3A and P-glycoprotein. PloS one 20120101
[Optimization of a compound prescription for treating liver fibrosis]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20120101
Effectiveness of Chinese herbal medicine in treating liver fibrosis: a systematic review and meta-analysis of randomized controlled trials. Chinese medicine 20120101
Protective effects of garlic oil on hepatocarcinoma induced by N-nitrosodiethylamine in rats. International journal of biological sciences 20120101
Current situation and perspectives of clinical study in integrative medicine in china. Evidence-based complementary and alternative medicine : eCAM 20120101
Hepatoprotective effect of Matrine salvianolic acid B salt on Carbon Tetrachloride-Induced Hepatic Fibrosis. Journal of inflammation (London, England) 20120101
Comparative analysis of quinolizidine alkaloids from different parts of Sophora alopecuroides seeds by UPLC-MS/MS. Journal of pharmaceutical and biomedical analysis 20120101
Understanding the mechanism of hepatic fibrosis and potential therapeutic approaches. Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20120101
Matrine inhibits breast cancer growth via miR-21/PTEN/Akt pathway in MCF-7 cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Antitumor activities of kushen: literature review. Evidence-based complementary and alternative medicine : eCAM 20120101
Alkaloids isolated from natural herbs as the anticancer agents. Evidence-based complementary and alternative medicine : eCAM 20120101
Matrine induces apoptosis in human acute myeloid leukemia cells via the mitochondrial pathway and Akt inactivation. PloS one 20120101
Antiinflammatory effects of matrine in LPS-induced acute lung injury in mice. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20111218
[Alcohol-purification technology and its particle sedimentation process in manufactory of Fufang Kushen injection]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20111101
[Meta analysis of compound matrine injection combined with cisplatin chemotherapy for advanced gastric cancer]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20111101
[TF-1 cell apoptosis-inducing effect of matrine and its effect on SALL4 expression]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20111001
Synthesis, structure-activity relationship and biological evaluation of novel N-substituted matrinic acid derivatives as host heat-stress cognate 70 (Hsc70) down-regulators. Bioorganic & medicinal chemistry letters 20110815
Matrine attenuates endotoxin-induced acute liver injury after hepatic ischemia/reperfusion in rats. Surgery today 20110801
Molecularly imprinted solid-phase extraction of matrine from radix Sophorae tonkinensis. The Analyst 20110721
Autophagy is involved in anticancer effects of matrine on SGC-7901 human gastric cancer cells. Oncology reports 20110701
The negative inotropic effects of homocysteine were prevented by matrine via the regulating intracellular calcium level. International journal of cardiology 20110701
Differential function of protective agents at each stage of the hypothermic preservation of hepatocytes. Journal of biochemistry 20110601
[Simultaneous determination of 7 alkaloid in herba Sophorae Alopecuroidis by HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110601
In vitro anti-tumour activities of quinolizidine alkaloids derived from Sophora flavescens Ait. Basic & clinical pharmacology & toxicology 20110501
Studies on the dynamic accumulations of Sophora alopecuroides L. Alkaloids in different harvest times and the appropriate harvest time. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110501
[Study on matrine alleviating retinoic acid resistance in acute promyelocytic leukemia]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110501
A novel solid-state electrochemiluminescence detector for capillary electrophoresis based on tris(2,2'-bipyridyl)ruthenium(II) immobilized in Nafion/PTC-NH2 composite film. Talanta 20110415
Matrine-imprinted monolithic stationary phase for extraction and purification of matrine from Sophorae flavescentis Ait. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110415
[Inhibitory effect of pyrrolidine dithiocarbamate combined with matrine on the growth of human hepatocellular carcinoma xenografts]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20110401
[Effect and mechanism of matrine on apoptosis of Raji cells]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110401
Matrine inhibits matrix metalloproteinase-9 expression and invasion of human hepatocellular carcinoma cells. Journal of Asian natural products research 20110301
[Studies on key processes of Fufang Kushen injection]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110301
Design and synthesis of oxymatrine analogues overcoming drug resistance in hepatitis B virus through targeting host heat stress cognate 70. Journal of medicinal chemistry 20110210
Potential new inorganic antitumour agents from combining the anticancer traditional Chinese medicine (TCM) matrine with Ga(III), Au(III), Sn(IV) ions, and DNA binding studies. Journal of inorganic biochemistry 20110201
Potential of Complementary and Alternative Medicine in Preventive Management of Novel H1N1 Flu (Swine Flu) Pandemic: Thwarting Potential Disasters in the Bud. Evidence-based complementary and alternative medicine : eCAM 20110101
Network target for screening synergistic drug combinations with application to traditional Chinese medicine. BMC systems biology 20110101
Matrine suppresses production of IL-23/IL-17 and ameliorates experimental autoimmune encephalomyelitis. The American journal of Chinese medicine 20110101
Macrophage autophagy and oxidative stress: an ultrastructural and immunoelectron microscopical study. Oxidative medicine and cellular longevity 20110101
Compound Kushen Injection suppresses human breast cancer stem-like cells by down-regulating the canonical Wnt/β-catenin pathway. Journal of experimental & clinical cancer research : CR 20110101
Hepatoprotective and antioxidant effects of licorice extract against CCl₄-induced oxidative damage in rats. International journal of molecular sciences 20110101
Synthesis and in vitro inhibitory activity of matrine derivatives towards pro-inflammatory cytokines. Bioorganic & medicinal chemistry letters 20101215
Effects of matrine and oxymatrine on catalytic activity of cytochrome p450s in rats. Basic & clinical pharmacology & toxicology 20101101
Effect of sophoridine on dextran sulfate sodium-induced colitis in C57BL/6 mice. Journal of Asian natural products research 20101101
Effect of matrine on human ether à go-go related gene (HERG) channels expressed in Chinese hamster ovary cells. Chinese journal of integrative medicine 20101001
Matrine inhibits vascular smooth muscle cell proliferation by modulating the expression of cell cycle regulatory genes. Acta pharmacologica Sinica 20101001
Antitumor effect of matrine in human hepatoma G2 cells by inducing apoptosis and autophagy. World journal of gastroenterology 20100914
Alkaloids from Sophora flavescens Aition. Fitoterapia 20100901
Preparation and in vitro evaluation of ethosomal total alkaloids of Sophora alopecuroides loaded by a transmembrane pH-gradient method. AAPS PharmSciTech 20100901
[Toxicity of matrine in Kunming mice]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20100901
[Simultaneous determination of five active components in compound preparation of Dangguishuan by high-performance liquid chromatography]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100901
Simultaneous stacking of cationic and anionic compounds in single run capillary zone electrophoresis by two-end field amplified sample injection. Journal of chromatography. A 20100827
A new A431/cell membrane chromatography and online high performance liquid chromatography/mass spectrometry method for screening epidermal growth factor receptor antagonists from Radix sophorae flavescentis. Journal of chromatography. A 20100806
Separation of flavonoid and alkaloid using collagen fiber adsorbent. Journal of separation science 20100801
[Pharmacokinetics and bioavailability of sustained-release tablets of matrine in dogs]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100801
Matrine induces apoptosis of human multiple myeloma cells via activation of the mitochondrial pathway. Leukemia & lymphoma 20100701
[Inhibitory effect of matrine on proliferation of human ovary malignant teratoma cell line PA-1 in vitro]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20100701
[Determination of matrine in Fufang Shen'an granules by HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100701
[Effect of ceftiofur hydrochloride on pharmacokinetics of matrine in rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100701
[Simultaneous determination of berberine, palmatine, matrine, catechin and baicalin in Funing Shuan by micellar electrokinetic capillary chromatography-electrospray ionization mass spectrometry]. Se pu = Chinese journal of chromatography 20100701
[Determination of matrine in matrine injection by microfluidic chip with contactless conductivity detection]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100701
Matrine inhibits 3T3-L1 preadipocyte differentiation associated with suppression of ERK1/2 phosphorylation. Biochemical and biophysical research communications 20100604
In situ gelling gelrite/alginate formulations as vehicles for ophthalmic drug delivery. AAPS PharmSciTech 20100601
Solid-phase extraction of matrine and oxymatrine from Sophora Flavescens Ait using amino-imidazolium polymer. Journal of separation science 20100601
[Effect of Matrine on cell cycle and human telomerase reverse transcriptase of human salivary adenoid cystic carcinoma]. Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20100601
Preparation and recognition performance of cytisine alkaloid-imprinted material prepared using novel surface molecular imprinting technique. Journal of separation science 20100501
[Study on pharmacokinetics of matrine by intramuscular administration in rat]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100501
[Suppressive effect of matrine on cell growth and decreases beta-catenin-dependent transcriptional activity in hepatoma cell line Hep3B]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100501
Biopharmaceutical and pharmacokinetic characterization of matrine as determined by a sensitive and robust UPLC-MS/MS method. Journal of pharmaceutical and biomedical analysis 20100406
Cardioprotective effect of matrine on isoproterenol-induced cardiotoxicity in rats. The Journal of pharmacy and pharmacology 20100401
[Comparison of ingredients between two water extractions of danggui kushen pills with or without solid-state fermentation]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100401
Multi-walled carbon nanotubes and Ru(bpy)3(2+)/nano-Au nano-sphere as efficient matrixes for a novel solid-state electrochemiluminescence sensor. Talanta 20100315
Effects of matrine on HepG2 cell proliferation and expression of tumor relevant proteins in vitro. Pharmaceutical biology 20100301
Preparation and evaluation of self-nanoemulsified drug delivery systems (SNEDDSs) of matrine based on drug-phospholipid complex technique. International journal of pharmaceutics 20100215
Matrine induces cell anergy in human Jurkat T cells through modulation of mitogen-activated protein kinases and nuclear factor of activated T-cells signaling with concomitant up-regulation of anergy-associated genes expression. Biological & pharmaceutical bulletin 20100101
[Epileptic seizure-like effect of Sophora alkaloid sophoridine on experimental animals]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100101
Total alkaloids of Sophora alopecuroides increases the expression of CD4+ CD25+ Tregs and IL-10 in rats with experimental colitis. The American journal of Chinese medicine 20100101
Preparation of RGD-modified long circulating liposome loading matrine, and its in vitro anti-cancer effects. International journal of medical sciences 20100101
Circumvention of multi-drug resistance of cancer cells by Chinese herbal medicines. Chinese medicine 20100101
Matrine inhibits proliferation and induces apoptosis of pancreatic cancer cells in vitro and in vivo. Biological & pharmaceutical bulletin 20100101
Therapeutic effects of matrine on primary and metastatic breast cancer. The American journal of Chinese medicine 20100101
Tissue culture and generation of autotetraploid plants of Sophora flavescens Aiton. Pharmacognosy magazine 20100101
Subacute fulminant hepatic failure with intermittent fever. Hepatobiliary & pancreatic diseases international : HBPD INT 20091201
Neuroprotective effects of an alkaloid-free ethyl acetate extract from the root of Sophora flavescens Ait. against focal cerebral ischemia in rats. Phytomedicine : international journal of phytotherapy and phytopharmacology 20091101
Matrine improves 17alpha-ethinyl estradiol-induced acute cholestasis in rats. Hepatology research : the official journal of the Japan Society of Hepatology 20091101
Extremely large volume electrokinetic stacking of cationic molecules in MEKC by EOF modulation with strong acids in sample solutions. Analytical chemistry 20091101
[The effect of matrine on the signal transduction pathway of transforming growth factor-beta1 in human lung fibroblast cells]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20091101
Matrine determination and pharmacokinetics in human plasma using LC/MS/MS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091001
[Changes and mechanism of apoptosis-related gene expression in T lymphocytic leukemia JM cells induced with matrine]. Zhongguo shi yan xue ye xue za zhi 20091001
Impact of matrine on inflammation related factors in rat intestinal microvascular endothelial cells. Journal of ethnopharmacology 20090925
Hepatoprotective and anti-hepatocarcinogenic effects of glycyrrhizin and matrine. Chemico-biological interactions 20090914
Antiarrhythmic properties of long-term treatment with matrine in arrhythmic rat induced by coronary ligation. Biological & pharmaceutical bulletin 20090901
[Effects of Hax-1 siRNA on sensitivity to chemotherapy of melanoma A375 cells]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20090901
[Effect and mechanism of matrine on adhesion and invasion of salivary gland adenoid cystic carcinoma cells in vitro]. Shanghai kou qiang yi xue = Shanghai journal of stomatology 20090801
[In vitro activity of matrine against Candida albicans biofilms]. Shanghai kou qiang yi xue = Shanghai journal of stomatology 20090801
Relaxant effects of matrine on aortic smooth muscles of guinea pigs. Biomedical and environmental sciences : BES 20090801
[The Role of Matrine and Mitogen-Ativated Protein Kinase/Extracellular Signal-Regulated Kinase Signal Transduction in the Inhibition of the Proliferation and Migration of Human Umbilical Veins Endothelial Cells Induced by Lung Cancer cells.]. Zhongguo fei ai za zhi = Chinese journal of lung cancer 20090720
Chemoprevention of lung squamous cell carcinoma in mice by a mixture of Chinese herbs. Cancer prevention research (Philadelphia, Pa.) 20090701
[Matrine enhances the cytotoxic sensitivity of ABCG2high nasopharyngeal carcinoma cells to natural killer cells by inducing high expression of NKG2D receptor ligands]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090701
[Lamivudine, interferon-alpha and oxymatrine treatment for the surviving hepatic failure patients with hepatitis B]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090701
Separation and mechanism elucidation for six structure-like matrine-type alkaloids by micellar liquid chromatography. Journal of separation science 20090601
[Effects of matrine on proliferation and telomerase activity of colon cancer SW1116 cells]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090601
[Apoptosis of U937 cell line promoted by matrine through MAPK signal transduction pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090601
Matrine induces apoptosis in gastric carcinoma cells via alteration of Fas/FasL and activation of caspase-3. Journal of ethnopharmacology 20090504
Hydration, erosion, and release behavior of guar-based hydrophilic matrix tablets containing total alkaloids of Sophora alopecuroides. Drug development and industrial pharmacy 20090501
Matrine induces programmed cell death and regulates expression of relevant genes based on PCR array analysis in C6 glioma cells. Molecular biology reports 20090401
Physiologically based pharmacokinetics of matrine in the rat after oral administration of pure chemical and ACAPHA. Drug metabolism and disposition: the biological fate of chemicals 20090401
Comparative effects of sophocarpine and sophoridine on hERG K+ channel. European journal of pharmacology 20090401
Effects of matrine against the growth of human lung cancer and hepatoma cells as well as lung cancer cell migration. Cytotechnology 20090401
Matrine suppresses breast cancer cell proliferation and invasion via VEGF-Akt-NF-kappaB signaling. Cytotechnology 20090401
[Effects of matrine on airway inflammation and early airway remodeling in asthmatic mice]. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20090301
[Study on pharmacokinetics and tissue distribution of stealth matrine liposomes in rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090301
Determination of oxymatrine and its metabolite matrine in rat blood and dermal microdialysates by high throughput liquid chromatography/tandem mass spectrometry. Journal of pharmaceutical and biomedical analysis 20090220
Wax-matrix tablet for time-dependent colon-specific delivery system of sophora flavescens Aiton: preparation and in vivo evaluation. Drug development and industrial pharmacy 20090201
Herbal plants as a promising source of natural antifoulants: evidence from barnacle settlement inhibition. Biofouling 20090101
Hepatoprotective effects of marine and kuhuang in liver transplant recipients. The American journal of Chinese medicine 20090101
Preparation of matrine ethosome, its percutaneous permeation in vitro and anti-inflammatory activity in vivo in rats. Journal of liposome research 20090101
Chinese medicines as a resource for liver fibrosis treatment. Chinese medicine 20090101
Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action. Molecular cancer 20090101
Sophocarpine and matrine inhibit the production of TNF-alpha and IL-6 in murine macrophages and prevent cachexia-related symptoms induced by colon26 adenocarcinoma in mice. International immunopharmacology 20081220
Actions of quinolizidine alkaloids on Periplaneta americana nicotinic acetylcholine receptors. Pest management science 20081201
Inhibitory effect of matrine on the expression of PSA and AR in prostate cancer cell line LNCaP. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20081201
Inotropic effects and mechanisms of matrine, a main alkaloid from Sophora flavescens AIT. Biological & pharmaceutical bulletin 20081101
[Effects of matrine on invasion and metastasis of leukemia cell line Jurkat]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20081001
[Effect of pectins of different degree of esterification on in-vitro sophoridine release of hydrophilic matrix tablets containing total alkaloids of Sophora alopecuroides]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081001
[Effect of matrine and oxymatrine on proliferation and expression of Stat3 and Stat5 in SMMC-7721 cell line]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081001
[Effects of matrine on the growth inhibition, c-myc and hTERT protein expression in human adenocarcinoma lung cancer cell line A549.]. Zhongguo fei ai za zhi = Chinese journal of lung cancer 20080820
Pharmacokinetic study of matrine, oxymatrine and oxysophocarpine in rat plasma after oral administration of Sophora flavescens Ait. extract by liquid chromatography tandem mass spectrometry. Journal of pharmaceutical and biomedical analysis 20080805
[Matrine inhibits the proliferation of prostate cancer cells and the activity of androgen receptor]. Zhonghua nan ke xue = National journal of andrology 20080801
[Simultaneous determination of matrine, oxysophocarpin and oxymatrine in rat plasma by HPLC-MS and its application in the pharmacokinetic study]. Yao xue xue bao = Acta pharmaceutica Sinica 20080801
[Matrine's inhibitory effect on apoptosis of cardiomyocytes induced by coxsackie virus B(3) and on calcium overload]. Zhonghua er ke za zhi = Chinese journal of pediatrics 20080801
[Effects of matrine, 5-fluorouracil and cisplatin on the expression of APRIL in hepatocellular carcinoma HepG2 cells]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20080701
[Effects of matrine on cgi-100 gene expression and proliferation in K562 cells]. Zhongguo shi yan xue ye xue za zhi 20080601
[Analysis of matrine and oxymatrine in Kushensu injection by UPLC/Q-TOF-MS]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080601
[Screening on alkaloid of Sophora alopecuraides against adenocarcinoma of colon cell line SW620 in vitro]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080601
Matrine inhibits invasiveness and metastasis of human malignant melanoma cell line A375 in vitro. International journal of dermatology 20080501
[Apoptotic mechanism of gastric carcinoma cells induced by matrine injection]. Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20080501
[Effects of matrine on oncogenicity of H22 cells modified by TIM2 gene in vivo]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080501
[Matrine inhibits the proliferation of neuroblastoma LA-N-5 cell and MYCN mRNA expression]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20080401
[Enhancing effect of matrine on the tumor-inhibition by TIM2 gene-modified hepatocarcinoma H22 cells in mice]. Zhonghua zhong liu za zhi [Chinese journal of oncology] 20080401
Analysis of quinolizidine alkaloids in Sophora flavescens Ait. by capillary electrophoresis with tris(2,2'-bipyridyl) ruthenium (II)-based electrochemiluminescence detection. Talanta 20080315
[Matrine-induced apoptosis in human colon adenocarcinoma SW620 cells]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080301
[Matrine-induced erythroid differentiation of K562 cells is associated with activation of the apoptotic pathway]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080301
Yessotoxins, a group of marine polyether toxins: an overview. Marine drugs 20080301
[Matrine and anti-tumor drugs in inhibiting the growth of human lung cancer cell line]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20080201
Anticancer effects of the Chinese medicine matrine on murine hepatocellular carcinoma cells. Planta medica 20080201
[Effects of matrine on the apoptosis and expression of adhesion molecule in multiple myeloma RMPI8226 cells]. Zhongguo shi yan xue ye xue za zhi 20080201
Synergistic action between jasmonic acid and nitric oxide in inducing matrine accumulation of Sophora flavescens suspension cells. Journal of integrative plant biology 20080101
Chinese herb related molecules of cancer-cell-apoptosis: a minireview of progress between Kanglaite injection and related genes. Journal of experimental & clinical cancer research : CR 20080101
Matrine inhibits PMA-induced MMP-1 expression in human dermal fibroblasts. BioFactors (Oxford, England) 20080101
Induced differentiation of hepatocellular carcinoma by natural products. African journal of traditional, complementary, and alternative medicines : AJTCAM 20080101
[Inhibition of NF-kappa B activity enhanced apoptosis induced by matrine in hepatocellular carcinoma cells]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20071201
[Simultaneous determination of contents of sophoridine, oxymatrine and oxysophocarpine in seed of Sophora alopecuroides by HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071201
[Preparation of total matrine controlled release micropellet capsules]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20071201
[The expression of IER3IP1 gene in K562 cells treated by matrine and its effect on the cell growth]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20071201
[Study on the preparation of matrine-containing nanocell]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20071001
[Influence of H2O2 on degradation of residual pesticides and constituents in Radix Sophorae Flavescentis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071001
Matrine inhibits the activity of translation factor eIF4E through dephosphorylation of 4E-BP1 in gastric MKN45 cells. Planta medica 20070901
[Studies on cutaneous permeation in vitro of Kushen recipe gel]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070901
Simultaneous determination and pharmacokinetic study of oxymatrine and matrine in beagle dog plasma after oral administration of Kushen formula granule, oxymatrine and matrine by LC-MS/MS. Biomedical chromatography : BMC 20070801
Sensitive quantitative determination of oxymatrine and matrine in rat plasma by capillary electrophoresis with stacking induced by moving reaction boundary. Analytica chimica acta 20070702
Simultaneous quantification of oxysophocarpine and its active metabolite sophocarpine in rat plasma by liquid chromatography/mass spectrometry for a pharmacokinetic study. Biomedical chromatography : BMC 20070701
Matrine induces apoptosis in angiotensin II-stimulated hyperplasia of cardiac fibroblasts: effects on Bcl-2/Bax expression and caspase-3 activation. Basic & clinical pharmacology & toxicology 20070701
[Preparation and in vivo evaluation of pH and time dependent Yuchangning tablets for colon-specific delivery]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070701
[Effect of matrine injections on invasion and metastasis of gastric carcinoma SGC-7901 cells in vitro]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070701
Effect of matrine on HeLa cell adhesion and migration. European journal of pharmacology 20070601
LC-MS characterization of efficacy substances in serum of experimental animals treated with Sophora flavescens extracts. Biomedical chromatography : BMC 20070601
Effect of matrine on the expression of substance P receptor and inflammatory cytokines production in human skin keratinocytes and fibroblasts. International immunopharmacology 20070601
[Experiment research on preventive effect of matrine on rat chronic nephrotoxicity induced by cyclosporin A]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20070601
Antifeedant activity and acute and residual toxicity of alkaloids from Sophora flavescens (leguminosae) against formosan subterranean termites (Isoptera: Rhinotermitidae). Journal of economic entomology 20070601
[Apoptosis of multiple myeloma RPMI8226 cell line induced by matrine]. Zhongguo shi yan xue ye xue za zhi 20070601
NACE-ESI-MS combined with on-line concentration for high-sensitivity analysis of quinolizidine alkaloids. Electrophoresis 20070501
[Effects of baicalin and other Chinese herbal monomer on androgen receptor mRNA expression in SZ95 sebocytes]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20070401
Supercritical fluid extraction of quinolizidine alkaloids from Sophora flavescens Ait. and purification by high-speed counter-current chromatography. Journal of chromatography. A 20070323
Matrine upregulates the cell cycle protein E2F-1 and triggers apoptosis via the mitochondrial pathway in K562 cells. European journal of pharmacology 20070322
Protective effect of glycyrrhizin, glycyrrhetic acid and matrine on acute cholestasis induced by alpha-naphthyl isothiocyanate in rats. Planta medica 20070201
Protective effect of glycyrrhizin and matrine on acute vanishing bile duct syndrome induced by alpha-naphthylisothiocyanate in rats. Hepatology research : the official journal of the Japan Society of Hepatology 20070201
[Matrine-induced gamma-globin synthesis in K562 cells]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20070201
[Determination of matrine, sophoridine and oxymatrine in Compound Kushen Injection by HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070201
[Effects of matrine, oxymatrine and resveratrol on HERG channel expression]. Yao xue xue bao = Acta pharmaceutica Sinica 20070201
Matrine induced gastric cancer MKN45 cells apoptosis via increasing pro-apoptotic molecules of Bcl-2 family. Toxicology 20070118
[Optimization of preparation for matrine-loaded magnetic chitosan microspheres]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070101
[HPCE determination of matrine in matrine liposome]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070101
[Inducement effect of matrine on phenotype changes of rat hepatic oval cells]. Ai zheng = Aizheng = Chinese journal of cancer 20061201
A rapid reversed phase high-performance liquid chromatographic method for determination of sophoridine in rat plasma and its application to pharmacokinetics studies. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061020
[An approach to the mechanism of matrine and albendazole against Echinococcus multilocularis infection in mice]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20061001
[Inhibition of extracts from 17 Chinese herbs on periodontal pathogenic microbes]. Shanghai kou qiang yi xue = Shanghai journal of stomatology 20060801
[Clinical observation on treatment of 75 mid-late stage cancer patients with yanshu Injection]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20060801
[Effects of matrine on proliferation and apoptosis of human renal cell carcinoma cell line GRC-1]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20060701
[The effects of matrine on cell proliferation and telomerase activity in retinoblastoma cells in vitro]. [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20060701
Determination and pharmacokinetic study of oxymatrine and its metabolite matrine in human plasma by liquid chromatography tandem mass spectrometry. Journal of pharmaceutical and biomedical analysis 20060607
Determination of quinolizidine alkaloids in Sophora flavescens and its preparation using capillary electrophoresis. Biomedical chromatography : BMC 20060501
Matrine-induced apoptosis in leukemia U937 cells: involvement of caspases activation and MAPK-independent pathways. Planta medica 20060501
[Constituents in the alkaloid fraction of Kushen decoction]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060401
Antiviral effects of sophoridine against coxsackievirus B3 and its pharmacokinetics in rats. Life sciences 20060320
Matrine improves 2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice. Pharmacological research 20060301
(+)-12alpha-Hydroxysophocarpine, a new quinolizidine alkaloid and related anti-HBV alkaloids from Sophora flavescens. Bioorganic & medicinal chemistry letters 20060301
Effect of matrine and carvedilol on collagen and MMPs activity of hypertrophy myocardium induced by pressure overload. Journal of Zhejiang University. Science. B 20060301
[Inhibition of invasiveness and expression of heparanase-mRNA in human malignant melanoma cell line A375 by matrine]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060301
Using LC/MS/MS to determine matrine, oxymatrine, ferulic acid, mangiferin, and glycyrrhizin in the Chinese medicinal preparations Shiau-feng-saan and Dang-guei-nian-tong-tang. Journal of pharmaceutical and biomedical analysis 20060213
[Experimental study on effect of matrine in alleviating renal tubulointerstitial fibrosis in unilateral ureteral obstruction model]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20060201
[Effects of Matrine Injection on T-lymphocyte subsets of patients with malignant tumor after gamma knife radiosurgery]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20060101
[Study of matrine's use on the reversion of obtained multi-drug resistance of mice S80 tumour cell]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060101
Molecular mechanism of matrine-induced apoptosis in leukemia K562 cells. The American journal of Chinese medicine 20060101
[Study on electrochemical kinetics of matrine and sophoridine in a physiological medium]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20051201
[The interference in correlated molecular mechanism obtained multi-drug resistance of mouse S180's tumour cell for different alkaloid]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20051201
Physicochemical characterization of the Strychnos alkaloids by capillary zone electrophoresis. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20051101
[Effect of matrine on regulating renal tubulointerstitial expression of MMP-3, TIMP-1 and FN]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20051101
Anti-hepatoma effect of arsenic trioxide on experimental liver cancer induced by 2-acetamidofluorene in rats. World journal of gastroenterology 20051014
A sensitive and specific HPLC-MS method for the determination of sophoridine, sophocarpine and matrine in rabbit plasma. Analytical and bioanalytical chemistry 20050801
Activities of fresh juice of Scutellaria barbata and warmed water extract of Radix Sophorae Tonkinensis on anti-proliferation and apoptosis of human cancer cell lines. International journal of molecular medicine 20050801
[HPLC-electrospray ionization ion trap tandem mass spectrometry analysis of oxymatrine and its metabolites in rat urine]. Yao xue xue bao = Acta pharmaceutica Sinica 20050801
[Clinical study of matrine injection on preventing liver function damage of anti-tumor drugs during chemotherapy of breast cancer]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20050801
[Clinical study on effect of matrine injection to protect the liver function for patients with primary hepatic carcinoma after trans-artery chemo-embolization (TAE)]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20050701
[Apoptosis of human oral epidermoid carcinoma KB cells and multidrug resistant KBv200 cells induced by matrine]. Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20050601
[Inhibition of tumor growth in tumor-bearing mice treated with matrine]. Zhonghua zhong liu za zhi [Chinese journal of oncology] 20050601
Implication of the descending dynorphinergic neuron projecting to the spinal cord in the (+)-matrine- and (+)-allomatrine-induced antinociceptive effects. Biological & pharmaceutical bulletin 20050501
[Study on direct electrochemical behaviors and the electroanalytical method of matrine type alkaloids at glassy carbon electrode]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050501
Simultaneous determination of oxymatrine and its active metabolite matrine in dog plasma by liquid chromatography-mass spectrometry and its application to pharmacokinetic studies. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050325
The involvement of central cholinergic system in (+)-matrine-induced antinociception in mice. Pharmacology, biochemistry, and behavior 20050301
[Study on inhibitory effect of matrine on cyclooxygenase-2 expression in colon cancer HT-29 cell line]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20050301
[Determination of sophoramine by spectrofluorimetry]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050201
Anti-HBV effect of liposome-encapsulated matrine in vitro and in vivo. World journal of gastroenterology 20050121
[Pharmacokinetics of oxymatrine and its metabolite in beagle dogs by LC-MS]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050101
Synergistic effects of matrine and 5-fluorouracil on tumor growth of the implanted gastric cancer in nude mice. Chinese journal of digestive diseases 20050101
[Studies on fingerprint spectrum of Radix Sophorae Tonkinensis from Guangxi]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20050101
Determination of quinolizidine alkaloids in Sophora tonkinensis by HPCE. Phytochemical analysis : PCA 20050101
Liquid chromatography of active principles in Sophora flavescens root. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041205
High-performance liquid chromatographic method for simultaneous determination of sophoridine and matrine in rat plasma. Biomedical chromatography : BMC 20041101
[Observation of pathological morphology on nervous system of rat with maximum dose sophoridine in chronic toxic test]. Ai zheng = Aizheng = Chinese journal of cancer 20041101
[The effect of matrine on the expression of P170 LRP and TOPO II of obtained multi-drug resistance of mouse S180's tumour cell]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20041101
[Renoprotective effects of matrine on experimental glomerulosclerosis in rats]. Zhonghua er ke za zhi = Chinese journal of pediatrics 20041001
Gas chromatography-mass spectrometry determination of matrine in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040905
[Comparison of the anti-arrhythmic effects of matrine and berbamine with amiodarone and RP58866]. Yao xue xue bao = Acta pharmaceutica Sinica 20040901
[Comparative analysis on effective compositions from tissue-cultured and wild Sophora tonkinensis]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20040801
[Gene expression profile in early differentiation of K562 cells induced by matrine]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20040601
[Inhibition of proliferation and influence of proto-oncogenes expression by matrine in C6 cell]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20040601
Separation and determination of aloperine, sophoridine, matrine and oxymatrine by combination of flow injection with microfluidic capillary electrophoresis. Talanta 20040528
Simultaneous determination of matrine, sophoridine and oxymatrine in Sophora flavescens Ait. by high performance liquid chromatography. Biomedical chromatography : BMC 20040401
Efficacy of intramuscular matrine in the treatment of chronic hepatitis B. Hepatobiliary & pancreatic diseases international : HBPD INT 20040201
[Progress of the study on effective integredients from Chinese herbal medicine in anti-tumor metastasis]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040201
[Recent research progress of anti-tumor mechnism matrine]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040201
[Techniques of diseases, insect pests and weeds control and their efficacy in bio-rational rice production]. Ying yong sheng tai xue bao = The journal of applied ecology 20040101
[Advance in the pharmacological research on matrine]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030901
[Study on the fingerprints of the alkaloids in Sophora flavescens]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030901
[Study on invasion and metastasis related factors in differentiation of SMMC-7721 cells induced by matrine]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20030801
[Matrine effects on JM cells by inhibiting proliferation and inducing apoptosis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030501
Determination of matrine in rat plasma by high-performance liquid chromatography and its application to pharmacokinetic studies. Talanta 20030410
Antinociceptive effects of N-acyloctahydropyrido[3,2,1-ij][1,6]naphthyridine in mice: structure-activity relation study of matrine-type alkaloids part II. Biological & pharmaceutical bulletin 20030301
TCM treatment of extrasystole with huanglian shengmai yin--a report of 357 cases. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 20030301
Effect of matrine on cold ischemia and reperfusion injury of sinusoidal endothelial cells in rat orthotopic liver transplantation. Acta pharmacologica Sinica 20030201
Preparative separation and determination of matrine from the Chinese medicinal plant Sophora flavescens Ait by molecularly imprinted solid-phase extraction. Analytical and bioanalytical chemistry 20030101
Matrine protects sinusoidal endothelial cells from cold ischemia and reperfusion injury in rat orthotopic liver transplantation. Annals of clinical and laboratory science 20030101
Radix Sophorae flavescentis for chronic hepatitis B: a systematic review of randomized trials. The American journal of Chinese medicine 20030101
Movement disorders possibly induced by traditional chinese herbs. European neurology 20030101
Effect of matrine on Kupffer cell activation in cold ischemia reperfusion injury of rat liver. World journal of gastroenterology 20021215
[Effects of matrine on the activity of protein tyrosine kinase and phosphatase in K562 cells]. Ai zheng = Aizheng = Chinese journal of cancer 20021201
[The influence of Matrine on apoptosis of fibroblasts and the expression of apoptotic modulation related protein in hypertrophic scar of rabbit ear]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20021001
Antinociceptive effects of 1-acyl-4-dialkylaminopiperidine and 1-alkyl-4-dialkylaminopiperidine in mice: structure-activity relation study of matrine-type alkaloids. Biological & pharmaceutical bulletin 20020801
Determination of matrine and oxymatrine in Sophora subprostata by CE. Journal of pharmaceutical and biomedical analysis 20020601
[Matrine affects early expression of proto-oncogenes in K562 cells]. Ai zheng = Aizheng = Chinese journal of cancer 20020401
Current studies on anti-endotoxic chemical components of traditional Chinese medicine in China. Acta pharmacologica Sinica 20011201
Indolizidine and quinolizidine alkaloids. Natural product reports 20011001
Effects of Matrine on proliferation and differentiation in K-562 cells. Leukemia research 20010901
Matrine inhibits production and actions of fibrogenic cytokines released by mouse peritoneal macrophages. Acta pharmacologica Sinica 20010801
[Effects of matrine on the relative molecules expression of proliferation and apoptosis in K562 cells]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20010801
Effects of matrine, artemisinin, tetrandrine on cytosolic [Ca2+]i in guinea pig ventricular myocytes. Acta pharmacologica Sinica 20010601
[Studies on metabolism of oxymatrine by human intestinal bacteria]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20010401
Antifibrotic effects of matrine on in vitro and in vivo models of liver fibrosis in rats. Acta pharmacologica Sinica 20010201
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