Home Halogens (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one

(4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one

CAS No.:
154598-52-4
Catalog Number:
AG0037PV
Molecular Formula:
C14H9ClF3NO2
Molecular Weight:
315.6750
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
98%(HPLC)
In Stock USA
United States
$66
- +
5g
98%(HPLC)
In Stock USA
United States
$122
- +
25g
98%(HPLC)
In Stock USA
United States
$390
- +
100g
98%(HPLC)
In Stock USA
United States
$1132
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Product Description
Catalog Number:
AG0037PV
Chemical Name:
(4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one
CAS Number:
154598-52-4
Molecular Formula:
C14H9ClF3NO2
Molecular Weight:
315.6750
MDL Number:
MFCD05662344
IUPAC Name:
(4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
InChI:
InChI=1S/C14H9ClF3NO2/c15-9-3-4-11-10(7-9)13(14(16,17)18,21-12(20)19-11)6-5-8-1-2-8/h3-4,7-8H,1-2H2,(H,19,20)/t13-/m0/s1
InChI Key:
XPOQHMRABVBWPR-ZDUSSCGKSA-N
SMILES:
FC([C@@]1(C#CC2CC2)OC(=O)Nc2c1cc(Cl)cc2)(F)F
UNII:
JE6H2O27P8
NSC Number:
742403
Properties
Complexity:
519  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
315.027g/mol
Formal Charge:
0
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
315.676g/mol
Monoisotopic Mass:
315.027g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
38.3A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4  
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The perils of relying on anti-hepatitis B total core antibody in screening individuals infected with HIV. International journal of STD & AIDS 20120201
Lipid profile changes in Thai HIV and tuberculosis co-infected patients receiving non-nucleoside reverse transcriptase inhibitors-based antiretroviral therapy. Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20120201
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Effects of vitamin D deficiency and combination antiretroviral therapy on bone in HIV-positive patients. AIDS (London, England) 20120128
Mutations in the HIV-1 reverse transcriptase tryptophan repeat motif affect virion maturation and Gag-Pol packaging. Virology 20120120
Effect of efavirenz on UDP-glucuronosyltransferase 1A1, 1A4, 1A6, and 1A9 activities in human liver microsomes. Molecules (Basel, Switzerland) 20120117
Evidence-based guideline: Antiepileptic drug selection for people with HIV/AIDS: report of the Quality Standards Subcommittee of the American Academy of Neurology and the Ad Hoc Task Force of the Commission on Therapeutic Strategies of the International League Against Epilepsy. Neurology 20120110
Antiretroviral prophylaxis and the risk of cleft lip and palate: preliminary signal detection in the food and drug administration's adverse events reporting system database. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 20120101
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Association between HIV infection, antiretroviral therapy, and risk of acute myocardial infarction: a cohort and nested case-control study using Québec's public health insurance database. Journal of acquired immune deficiency syndromes (1999) 20110701
The male genital tract is not a pharmacological sanctuary from efavirenz. Clinical pharmacology and therapeutics 20110701
Impact of HAART exposure and associated lipodystrophy on advanced liver fibrosis in HIV/HCV-coinfected patients. Journal of viral hepatitis 20110701
Usefulness of methadone plasma concentration measurement in patients receiving nevirapine or efavirenz. The American journal of drug and alcohol abuse 20110701
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Bioactive neolignans and lignans from the bark of Machilus robusta. Journal of natural products 20110624
Lindenane disesquiterpenoids with anti-HIV-1 activity from Chloranthus japonicus. Journal of natural products 20110624
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Surface-active derivative of inulin (Inutec® SP1) is a superior carrier for solid dispersions with a high drug load. Journal of pharmaceutical sciences 20110601
Identification of human UGT isoforms responsible for glucuronidation of efavirenz and its three hydroxy metabolites. Xenobiotica; the fate of foreign compounds in biological systems 20110601
Non-nucleoside reverse transcriptase inhibitors efavirenz and nevirapine inhibit cytochrome C oxidase in mouse brain regions. Neurochemical research 20110601
The HIV protease inhibitor nelfinavir inhibits Kaposi's sarcoma-associated herpesvirus replication in vitro. Antimicrobial agents and chemotherapy 20110601
Integration of population pharmacokinetics and pharmacogenetics: an aid to optimal nevirapine dose selection in HIV-infected individuals. The Journal of antimicrobial chemotherapy 20110601
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Therapeutic drug monitoring of protease inhibitors and efavirenz in HIV-infected individuals with active substance-related disorders. Therapeutic drug monitoring 20110601
Management of HIV infection in treatment-naive patients: a review of the most current recommendations. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110601
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AIDS diarrhea and antiretroviral drug concentrations: a matched-pair cohort study in Port au Prince, Haiti. The American journal of tropical medicine and hygiene 20110601
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The effect of highly active antiretroviral therapy on the survival of HIV-infected children in a resource-deprived setting: a cohort study. PLoS medicine 20110601
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Major HIV resistance mutations in untreated Romanian patients. Journal of medicine and life 20110515
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Change in high-sensitivity c-reactive protein levels following initiation of efavirenz-based antiretroviral regimens in HIV-infected individuals. AIDS research and human retroviruses 20110501
Molecular recognition of the antiretroviral drug abacavir: towards the development of a novel carbazole-based fluorosensor. Journal of fluorescence 20110501
Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases. The FEBS journal 20110501
HIV-1 integrase inhibitor resistance and its clinical implications. The Journal of infectious diseases 20110501
Effectiveness of early antiretroviral therapy initiation to improve survival among HIV-infected adults with tuberculosis: a retrospective cohort study. PLoS medicine 20110501
CTL escape mediated by proteasomal destruction of an HIV-1 cryptic epitope. PLoS pathogens 20110501
Inhibition of both HIV-1 reverse transcription and gene expression by a cyclic peptide that binds the Tat-transactivating response element (TAR) RNA. PLoS pathogens 20110501
Hepatotoxicity in patients co-infected with tuberculosis and HIV-1 while receiving non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy and rifampicin-containing anti-tuberculosis regimen. The Southeast Asian journal of tropical medicine and public health 20110501
Human immunodeficiency virus therapeutics and pharmacogenomics. Indian journal of human genetics 20110501
Diarylpyrimidine-dihydrobenzyloxopyrimidine hybrids: new, wide-spectrum anti-HIV-1 agents active at (sub)-nanomolar level. Journal of medicinal chemistry 20110428
Efficacy of NNRTI-based antiretroviral therapy initiated during acute HIV infection. AIDS (London, England) 20110424
Hospitalization for severe malnutrition among HIV-infected children starting antiretroviral therapy. AIDS (London, England) 20110424
Efavirenz associated with cognitive disorders in otherwise asymptomatic HIV-infected patients. Neurology 20110419
A randomized crossover study to determine relative bioequivalence of tenofovir, emtricitabine, and efavirenz (Atripla) fixed-dose combination tablet compared with a compounded oral liquid formulation derived from the tablet. Journal of acquired immune deficiency syndromes (1999) 20110415
Atazanavir plus ritonavir or efavirenz as part of a 3-drug regimen for initial treatment of HIV-1. Annals of internal medicine 20110405
Cohort profile: Hlabisa HIV treatment and care programme. International journal of epidemiology 20110401
Proper laboratory notebook practices: protecting your intellectual property. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20110401
Cost-effectiveness of atazanavir/ritonavir compared with lopinavir/ritonavir in treatment-naïve human immunodeficiency virus-1 patients in Sweden. Scandinavian journal of infectious diseases 20110401
Impact of the N348I mutation in HIV-1 reverse transcriptase on nonnucleoside reverse transcriptase inhibitor resistance in non-subtype B HIV-1. Antimicrobial agents and chemotherapy 20110401
[HIV infected women with intense bone and muscular pain and general weakness]. Enfermedades infecciosas y microbiologia clinica 20110401
Failure of initial therapy with two nucleosides and efavirenz is not associated with early emergence of mutations in the C-terminus of HIV-1 reverse transcriptase. Journal of acquired immune deficiency syndromes (1999) 20110401
Cardiovascular risk factors in patients on long-term treatment with nevirapine- or efavirenz-based regimens. The Journal of antimicrobial chemotherapy 20110401
In silico prediction of efavirenz and rifampicin drug-drug interaction considering weight and CYP2B6 phenotype. British journal of clinical pharmacology 20110401
Management of adult active tuberculosis disease in era of HIV pandemic, current practices and future perspectives. Infectious disorders drug targets 20110401
First-line antiretroviral treatment of HIV-infected children. A choice largely based on adult data. Prescrire international 20110401
[Comparative study of two anti-antiretroviral protocols used for treatment of a cohort of HIV 1-positive patients followed at the Institute of Public Health and Hygiene in Dakar, Senegal]. Medecine tropicale : revue du Corps de sante colonial 20110401
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Clinical applications of drug desensitization in the Asia-Pacific region. Asia Pacific allergy 20110401
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Is lower serum 25-hydroxy vitamin D associated with efavirenz or the non-nucleoside reverse transcriptase inhibitor class? AIDS (London, England) 20110327
A HPLC-MS method for the simultaneous quantification of fourteen antiretroviral agents in peripheral blood mononuclear cell of HIV infected patients optimized using medium corpuscular volume evaluation. Journal of pharmaceutical and biomedical analysis 20110325
Indolylarylsulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors: new cyclic substituents at indole-2-carboxamide. Journal of medicinal chemistry 20110324
Asymmetric autocatalysis enables an improved synthesis of efavirenz. Angewandte Chemie (International ed. in English) 20110321
Analyses of nanoformulated antiretroviral drug charge, size, shape and content for uptake, drug release and antiviral activities in human monocyte-derived macrophages. Journal of controlled release : official journal of the Controlled Release Society 20110310
Bone mineral density changes in protease inhibitor-sparing vs. nucleoside reverse transcriptase inhibitor-sparing highly active antiretroviral therapy: data from a randomized trial. HIV medicine 20110301
Virologic failure and second-line antiretroviral therapy in children in South Africa--the IeDEA Southern Africa collaboration. Journal of acquired immune deficiency syndromes (1999) 20110301
Oral pharmacokinetics of the anti-HIV efavirenz encapsulated within polymeric micelles. Biomaterials 20110301
HIV/HCV co-infection: pathogenesis, clinical complications, treatment, and new therapeutic technologies. Current HIV/AIDS reports 20110301
Lactic acidosis after concomitant treatment with metformin and tenofovir in a patient with HIV infection. Journal of renal care 20110301
Age-related skeletal muscle decline is similar in HIV-infected and uninfected individuals. The journals of gerontology. Series A, Biological sciences and medical sciences 20110301
A randomized controlled trial comparing the effects of counseling and alarm device on HAART adherence and virologic outcomes. PLoS medicine 20110301
Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculations. PLoS computational biology 20110301
Mycobacterium lentiflavum in drinking water supplies, Australia. Emerging infectious diseases 20110301
HIV-1 drug resistance emergence among breastfeeding infants born to HIV-infected mothers during a single-arm trial of triple-antiretroviral prophylaxis for prevention of mother-to-child transmission: a secondary analysis. PLoS medicine 20110301
Depressogenic effects of medications: a review. Dialogues in clinical neuroscience 20110301
Hepatotoxicity from first line antiretroviral therapy: an experience from a resource limited setting. African health sciences 20110301
Viral decay rates are similar in HIV-infected patients with and without TB coinfection during treatment with an Efavirenz-based regimen. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20110215
Dyslipidemia among HIV-infected Patients with tuberculosis taking once-daily nonnucleoside reverse-transcriptase inhibitor-based antiretroviral therapy in India. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20110215
Dream changes following initiation of efavirenz treatment. Medicina clinica 20110212
Quantifying the risks and benefits of efavirenz use in HIV-infected women of childbearing age in the USA. HIV medicine 20110201
Theoretical studies on the molecular basis of HIV-1RT/NNRTIs interactions. Journal of enzyme inhibition and medicinal chemistry 20110201
Estimating the risk of HIV transmission from homosexual men receiving treatment to their HIV-uninfected partners. Sexually transmitted infections 20110201
[Two cases of Fanconi's syndrome induced by tenofovir in the Ivory Coast]. Medecine et maladies infectieuses 20110201
Standard measures are inadequate to monitor pediatric adherence in a resource-limited setting. AIDS and behavior 20110201
Pregnancy outcomes in women exposed to efavirenz and nevirapine: an appraisal of the IeDEA West Africa and ANRS Databases, Abidjan, Côte d'Ivoire. Journal of acquired immune deficiency syndromes (1999) 20110201
Long-term effectiveness and safety of didanosine combined with lamivudine and efavirenz or nevirapine in antiretroviral-naive patients: a 9-year cohort study in Senegal. Tropical medicine & international health : TM & IH 20110201
Efavirenz concentrations in CSF exceed IC50 for wild-type HIV. The Journal of antimicrobial chemotherapy 20110201
In Vitro antiretroviral properties of S/GSK1349572, a next-generation HIV integrase inhibitor. Antimicrobial agents and chemotherapy 20110201
Approach to dyslipidemia, lipodystrophy, and cardiovascular risk in patients with HIV infection. Current atherosclerosis reports 20110201
Adherence to HIV therapeutic drug monitoring guidelines in The Netherlands. Therapeutic drug monitoring 20110201
Low vitamin D among HIV-infected adults: prevalence of and risk factors for low vitamin D Levels in a cohort of HIV-infected adults and comparison to prevalence among adults in the US general population. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20110201
Pharmacokinetic interaction between efavirenz and rifampicin in healthy volunteers. International journal of clinical pharmacology and therapeutics 20110201
Lack of effect from a previous single dose of nevirapine on virologic and immunologic responses after 6 months of antiretroviral regimens containing either efavirenz or lopinavir-ritonavir. Pharmacotherapy 20110201
Hepatitis E virus and neurologic disorders. Emerging infectious diseases 20110201
Clinical Trial Report: TMC278 (Rilpivirine) Versus Efavirenz as Initial Therapy in Treatment-Naïve, HIV-1-Infected Patients. Current infectious disease reports 20110201
Genital tract sequestration of SIV following acute infection. PLoS pathogens 20110201
Nevirapine induced Stevens-Johnson syndrome in an HIV infected patient. Indian journal of pharmacology 20110201
Paradoxically elevated efavirenz concentrations in HIV/tuberculosis-coinfected patients with CYP2B6 516TT genotype on rifampin-containing antituberculous therapy. AIDS (London, England) 20110128
A comparison of neuropsychiatric adverse events during 12 weeks of treatment with etravirine and efavirenz in a treatment-naive, HIV-1-infected population. AIDS (London, England) 20110128
Higher efficacy of nevirapine than efavirenz to achieve HIV-1 plasma viral load below 1 copy/ml. AIDS (London, England) 20110128
Low level of the K103N HIV-1 above a threshold is associated with virological failure in treatment-naive individuals undergoing efavirenz-containing therapy. AIDS (London, England) 20110128
Association of pharmacogenetic markers with premature discontinuation of first-line anti-HIV therapy: an observational cohort study. The Journal of infectious diseases 20110115
Allosteric suppression of HIV-1 reverse transcriptase structural dynamics upon inhibitor binding. Biophysical journal 20110105
European mitochondrial DNA haplogroups and metabolic changes during antiretroviral therapy in AIDS Clinical Trials Group Study A5142. AIDS (London, England) 20110102
A randomized crossover study to compare efavirenz and etravirine treatment. AIDS (London, England) 20110102
A phase IV, double-blind, multicentre, randomized, placebo-controlled, pilot study to assess the feasibility of switching individuals receiving efavirenz with continuing central nervous system adverse events to etravirine. AIDS (London, England) 20110102
Anti-HIV drugs nevirapine and efavirenz affect anxiety-related behavior and cognitive performance in mice. Neurotoxicity research 20110101
Improvement in vitamin D deficiency following antiretroviral regime change: Results from the MONET trial. AIDS research and human retroviruses 20110101
Stavudine toxicity in women is the main reason for treatment change in a 3-year prospective cohort of adult patients started on first-line antiretroviral treatment in Uganda. Journal of acquired immune deficiency syndromes (1999) 20110101
Determination of the antiretroviral drug nevirapine in diluted alkaline electrolyte by adsorptive stripping voltammetry at the mercury film electrode. Combinatorial chemistry & high throughput screening 20110101
Drug susceptibility of human immunodeficiency virus type 1-derived pseudoviruses from treatment-experienced patients to protease inhibitors and reverse transcriptase inhibitors, using a modified single-round assay. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20110101
Four year follow-up of simplification therapy with once-daily emtricitabine, didanosine and efavirenz in HIV-infected patients (ALIZE ANRS 099 trial). The Journal of antimicrobial chemotherapy 20110101
[Immune reconstitution inflammatory syndrome associated with eosinophilic pustular folliculitis in an HIV-infected patient]. Medecine et maladies infectieuses 20110101
[Rate of genotypic mutations and resistance to antiretroviral drugs in a general hospital]. Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20110101
The assessment of metabolic syndrome in UK patients with HIV using two different definitions: CREATE 2 study. Current medical research and opinion 20110101
The toxicogenetics of antiretroviral therapy: the evil inside. Current medicinal chemistry 20110101
Use of biological knowledge to inform the analysis of gene-gene interactions involved in modulating virologic failure with efavirenz-containing treatment regimens in ART-naïve ACTG clinical trials participants. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 20110101
Immunophenotypical Switch versus Tumor Heterogeneity in a Patient with HIV-Associated Diffuse Large B-Cell Lymphoma. Pathology research international 20110101
Long-term safety from the raltegravir clinical development program. Current HIV research 20110101
Aminotransferase serum levels decrease after initiating antiretroviral treatment in HIV infected patients. Current HIV research 20110101
Understanding diabetes in patients with HIV/AIDS. Diabetology & metabolic syndrome 20110101
Timing of antiretroviral therapy for HIV in the setting of TB treatment. Clinical & developmental immunology 20110101
Expenditures for the care of HIV-infected patients in rural areas in China's antiretroviral therapy programs. BMC medicine 20110101
An antiretroviral/zinc combination gel provides 24 hours of complete protection against vaginal SHIV infection in macaques. PloS one 20110101
K70Q adds high-level tenofovir resistance to 'Q151M complex' HIV reverse transcriptase through the enhanced discrimination mechanism. PloS one 20110101
Genital warts and infection with human immunodeficiency virus in high-risk women in Burkina Faso: a longitudinal study. BMC infectious diseases 20110101
Quality of data collection in a large HIV observational clinic database in sub-Saharan Africa: implications for clinical research and audit of care. Journal of the International AIDS Society 20110101
Culture conversion among HIV co-infected multidrug-resistant tuberculosis patients in Tugela Ferry, South Africa. PloS one 20110101
Replicative phenotyping adds value to genotypic resistance testing in heavily pre-treated HIV-infected individuals--the Swiss HIV Cohort Study. Journal of translational medicine 20110101
Long-term CD4+ T-cell count evolution after switching from regimens including HIV nucleoside reverse transcriptase inhibitors (NRTI) plus protease inhibitors to regimens containing NRTI plus non-NRTI or only NRTI. BMC infectious diseases 20110101
Clinical use of CCR5 inhibitors in HIV and beyond. Journal of translational medicine 20110101
Intensified treatment with high dose rifampicin and levofloxacin compared to standard treatment for adult patients with tuberculous meningitis (TBM-IT): protocol for a randomized controlled trial. Trials 20110101
Human immunodeficiency virus type 2 in two Saudi families. Annals of Saudi medicine 20110101
[Study of meta-trajectories of CD4 cells count from taxonomy in the antiretroviral response of efavirenz-based regimen with naive symptomatic patients in Abidjan]. Annales pharmaceutiques francaises 20110101
Adherence and virologic suppression during the first 24 weeks on antiretroviral therapy among women in Johannesburg, South Africa - a prospective cohort study. BMC public health 20110101
A biregional survey and review of first-line treatment failure and second-line paediatric antiretroviral access and use in Asia and southern Africa. Journal of the International AIDS Society 20110101
Development of Buffalo Hump in the course of antiretroviral therapy including raltegravir and unboosted atazanavir: a case report and review of the literature. Journal of medical case reports 20110101
HIV-1 infected patients with suppressed plasma viremia on treatment have pro-inflammatory HDL. Lipids in health and disease 20110101
Alanine zipper-like coiled-coil domains are necessary for homotypic dimerization of plant GAGA-factors in the nucleus and nucleolus. PloS one 20110101
Management of HIV-1 associated hepatitis in patients with acquired immunodeficiency syndrome: role of a successful control of viral replication. AIDS research and therapy 20110101
Weight and height z-scores improve after initiating ART among HIV-infected children in rural Zambia: a cohort study. BMC infectious diseases 20110101
Timely HAART initiation may pave the way for a better viral control. BMC infectious diseases 20110101
Efavirenz-based combination antiretroviral therapy after peripartum single-dose nevirapine. International journal of STD & AIDS 20110101
Neurobehavioral effects in HIV-positive individuals receiving highly active antiretroviral therapy (HAART) in Gaborone, Botswana. PloS one 20110101
Prevalence of potential drug-drug interactions involving antiretroviral drugs in a large Kenyan cohort. PloS one 20110101
Rilpivirine: a new addition to the anti-HIV-1 armamentarium. Drugs of today (Barcelona, Spain : 1998) 20110101
Correcting for mortality among patients lost to follow up on antiretroviral therapy in South Africa: a cohort analysis. PloS one 20110101
Antiretroviral therapy outcomes in HIV-infected children after adjusting protease inhibitor dosing during tuberculosis treatment. PloS one 20110101
Time for gender mainstreaming in editorial policies. Journal of the International AIDS Society 20110101
Incidence and predictors of immune reconstitution inflammatory syndrome in a rural area of Mozambique. PloS one 20110101
Drug efficacy by direct and adjusted indirect comparison to placebo: An illustration by Mycobacterium avium complex prophylaxis in HIV. AIDS research and therapy 20110101
Maraviroc can improve lipid profiles in dyslipidemic patients with HIV: results from the MERIT trial. HIV clinical trials 20110101
'Dynamic range' of inferred phenotypic HIV drug resistance values in clinical practice. PloS one 20110101
Renal safety of a tenofovir-containing first line regimen: experience from an antiretroviral cohort in rural Lesotho. PloS one 20110101
Highly active antiretroviral therapy: Does it Sound toxic? Journal of pharmacy & bioallied sciences 20110101
Driving a decade of change: HIV/AIDS, patents and access to medicines for all. Journal of the International AIDS Society 20110101
The effect of efavirenz on the pharmacokinetics of an oral contraceptive containing ethinyl estradiol and norgestimate in healthy HIV-negative women. Antiviral therapy 20110101
Successful efavirenz dose reduction guided by therapeutic drug monitoring. Antiviral therapy 20110101
Interaction between antiretroviral drugs and acenocoumarol. Antiviral therapy 20110101
Machine learning on normalized protein sequences. BMC research notes 20110101
Patient-reported adverse drug reactions and drug-drug interactions: a cross-sectional study on Malaysian HIV/AIDS patients. Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20110101
HIV quasispecies dynamics during pro-active treatment switching: impact on multi-drug resistance and resistance archiving in latent reservoirs. PloS one 20110101
Comparison of intima-media thickness and ophthalmic artery resistance index for assessing subclinical atherosclerosis in HIV-1-infected patients. Cardiovascular ultrasound 20110101
Cost effectiveness of a pharmacy-only refill program in a large urban HIV/AIDS clinic in Uganda. PloS one 20110101
Open-label randomized multicenter selection study of once daily antiretroviral treatment regimen comparing ritonavir-boosted atazanavir to efavirenz with fixed-dose abacavir and lamivudine. Internal medicine (Tokyo, Japan) 20110101
Nutrition and inflammation serum biomarkers are associated with 12-week mortality among malnourished adults initiating antiretroviral therapy in Zambia. Journal of the International AIDS Society 20110101
Results of antiretroviral treatment interruption and intensification in advanced multi-drug resistant HIV infection from the OPTIMA trial. PloS one 20110101
Activation of latent HIV using drug-loaded nanoparticles. PloS one 20110101
Four-year treatment outcomes of adult patients enrolled in Mozambique's rapidly expanding antiretroviral therapy program. PloS one 20110101
Pharmacology and metabolism of anidulafungin, caspofungin and micafungin in the treatment of invasive candidosis: review of the literature. European journal of medical research 20110101
HIV-1 accessory protein Vpr: relevance in the pathogenesis of HIV and potential for therapeutic intervention. Retrovirology 20110101
HIV Suppression among Patients on Treatment in Vietnam: A Review of HIV Viral Load Testing in a Public Urban Clinic in Ho Chi Minh City. AIDS research and treatment 20110101
Long-Term Outcome of an HIV-Treatment Programme in Rural Africa: Viral Suppression despite Early Mortality. AIDS research and treatment 20110101
Antiretroviral Therapy for HIV-2 Infection: Recommendations for Management in Low-Resource Settings. AIDS research and treatment 20110101
Outcomes of Universal Access to Antiretroviral Therapy (ART) in Georgia. AIDS research and treatment 20110101
Utilization patterns and projected demand of antiretroviral drugs in low- and middle-income countries. AIDS research and treatment 20110101
A risk-factor guided approach to reducing lactic acidosis and hyperlactatemia in patients on antiretroviral therapy. PloS one 20110101
Reduced emergence of the M184V/I resistance mutation when antiretroviral-naïve subjects use emtricitabine versus lamivudine in regimens composed of two NRTIs plus the NNRTI efavirenz. HIV clinical trials 20110101
Improved antiretroviral treatment outcome in a rural African setting is associated with cART initiation at higher CD4 cell counts and better general health condition. BMC infectious diseases 20110101
Long-term renal safety of tenofovir disoproxil fumarate in vertically HIV-infected children, adolescents and young adults: a 60-month follow-up study. Clinical drug investigation 20110101
Excellent adherence to antiretrovirals in HIV+ Zambian children is compromised by disrupted routine, HIV nondisclosure, and paradoxical income effects. PloS one 20110101
HIV-Associated Tuberculosis in the Newborn and Young Infant. International journal of pediatrics 20110101
Evaluation of WHO Criteria for Viral Failure in Patients on Antiretroviral Treatment in Resource-Limited Settings. AIDS research and treatment 20110101
Effect of reverse transcriptase inhibitors on LINE-1 and Ty1 reverse transcriptase activities and on LINE-1 retrotransposition. BMC biochemistry 20110101
Economic modeling of the combined effects of HIV-disease, cholesterol and lipoatrophy based on ACTG 5142 trial data. Cost effectiveness and resource allocation : C/E 20110101
Performance of Cpred/Cobs concentration ratios as a metric reflecting adherence to antidepressant drug therapy. Neuropsychiatric disease and treatment 20110101
HIV-infected children in rural Zambia achieve good immunologic and virologic outcomes two years after initiating antiretroviral therapy. PloS one 20110101
Targeted maximum likelihood estimation of effect modification parameters in survival analysis. The international journal of biostatistics 20110101
Factors influencing retention in care after starting antiretroviral therapy in a rural South African programme. PloS one 20110101
Inhibitory activity of 9-phenylcyclohepta[d]pyrimidinedione derivatives against different strains of HIV-1 as non-nucleoside reverse transcriptase inhibitors. Virology journal 20110101
Cross-sectional detection of acute HIV infection: timing of transmission, inflammation and antiretroviral therapy. PloS one 20110101
The net cost of incorporating resistance testing into HIV/AIDS treatment in South Africa: a Markov model with primary data. Journal of the International AIDS Society 20110101
Virologic outcomes of HAART with concurrent use of cytochrome P450 enzyme-inducing antiepileptics: a retrospective case control study. AIDS research and therapy 20110101
The role of HIV and antiretroviral therapy in bone disease. AIDS reviews 20110101
Contribution of cytochrome P450 and ABCB1 genetic variability on methadone pharmacokinetics, dose requirements, and response. PloS one 20110101
Barriers to initiation of antiretrovirals during antituberculosis therapy in Africa. PloS one 20110101
Predicted susceptibility of etravirine in HIV patients experiencing virological failure secondary to non-nucleoside reverse transcriptase inhibitor resistance in Argentina. Enfermedades infecciosas y microbiologia clinica 20110101
Clinical utility of maraviroc. Clinical drug investigation 20110101
Marked increase in etravirine and saquinavir plasma concentrations during atovaquone/proguanil prophylaxis. Malaria journal 20110101
Added value of deep sequencing relative to population sequencing in heavily pre-treated HIV-1-infected subjects. PloS one 20110101
Management of the kidney transplant patient with chronic hepatitis C infection. International journal of nephrology 20110101
Safety and tolerability of antiretrovirals during pregnancy. Infectious diseases in obstetrics and gynecology 20110101
Incidence and risk factors of serious adverse events during antituberculous treatment in Rwanda: a prospective cohort study. PloS one 20110101
Asking the right questions: developing evidence-based strategies for treating HIV in women and children. BMC public health 20110101
Presentation and outcome of tuberculous meningitis in a high HIV prevalence setting. PloS one 20110101
Outcome assessment of a dedicated HIV positive health care worker clinic at a central hospital in Malawi: a retrospective observational study. PloS one 20110101
Contraception in HIV-positive female adolescents. AIDS research and therapy 20110101
HIV and HAART-Associated Dyslipidemia. The open cardiovascular medicine journal 20110101
A template-dependent dislocation mechanism potentiates K65R reverse transcriptase mutation development in subtype C variants of HIV-1. PloS one 20110101
Impact of UGT2B7 His268Tyr polymorphism on the outcome of adjuvant epirubicin treatment in breast cancer. Breast cancer research : BCR 20110101
Clinical predictors of immune reconstitution following combination antiretroviral therapy in patients from the Australian HIV Observational Database. PloS one 20110101
On-line reaction monitoring of lithiation of halogen substituted acetanilides via in situ calorimetry, ATR spectroscopy, and endoscopy. Chimia 20110101
Use of non-nucleoside analogues together with rifampin in HIV patients with tuberculosis. HIV clinical trials 20110101
Efavirenz and rifampicin in the South African context: is there a need to dose-increase efavirenz with concurrent rifampicin therapy? Antiviral therapy 20110101
Lactic acidosis and symptomatic hyperlactataemia in a randomized trial of first-line therapy in HIV-infected adults in South Africa. Antiviral therapy 20110101
Update on the optimal use of voriconazole for invasive fungal infections. Infection and drug resistance 20110101
Patterns of resistance development with integrase inhibitors in HIV. Infection and drug resistance 20110101
Surveillance of transmitted antiretroviral drug resistance among HIV-1 infected women attending antenatal clinics in Chitungwiza, Zimbabwe. PloS one 20110101
Early mortality and AIDS progression despite high initial antiretroviral therapy adherence and virologic suppression in Botswana. PloS one 20110101
Rebound of residual plasma viremia after initial decrease following addition of intravenous immunoglobulin to effective antiretroviral treatment of HIV. AIDS research and therapy 20110101
Immune reconstitution and inflammatory syndrome due to disseminated tuberculosis in a case of human immunodeficiency virus 2 infection. Indian journal of pharmacology 20110101
Tenofovir nephrotoxicity: 2011 update. AIDS research and treatment 20110101
Virological breakthrough: a risk factor for loss to followup in a large community-based cohort on antiretroviral therapy. AIDS research and treatment 20110101
The role of unintegrated DNA in HIV infection. Retrovirology 20110101
Oral lesions associated with nevirapine-related Stevens Johnson syndrome: A report of four cases. Journal of oral and maxillofacial pathology : JOMFP 20110101
Tuberculosis: current situation, challenges and overview of its control programs in India. Journal of global infectious diseases 20110101
Improved survival of HIV-1-infected patients with progressive multifocal leukoencephalopathy receiving early 5-drug combination antiretroviral therapy. PloS one 20110101
Minor HIV-1 variants with the K103N resistance mutation during intermittent efavirenz-containing antiretroviral therapy and virological failure. PloS one 20110101
Time to and Predictors of CD4+ T-Lymphocytes Recovery in HIV-Infected Children Initiating Highly Active Antiretroviral Therapy in Ghana. AIDS research and treatment 20110101
Antiretroviral treatment reverses HIV-associated anemia in rural Tanzania. BMC infectious diseases 20110101
Association of age with mortality and virological and immunological response to antiretroviral therapy in rural South African adults. PloS one 20110101
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Alternative antiretroviral monitoring strategies for HIV-infected patients in east Africa: opportunities to save more lives? Journal of the International AIDS Society 20110101
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Lyme neuroborreliosis in HIV-1 positive men successfully treated with oral doxycycline: a case series and literature review. Journal of medical case reports 20110101
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Calculation of direct antiretroviral treatment costs and potential cost savings by using generics in the German HIV ClinSurv cohort. PloS one 20110101
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Nevirapine plasma concentrations are associated with virologic response and hepatotoxicity in Chinese patients with HIV infection. PloS one 20110101
An inducible cell-cell fusion system with integrated ability to measure the efficiency and specificity of HIV-1 entry inhibitors. PloS one 20110101
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Effect of anemia on hepatotoxicity of HAART in HIV patients in Benin city. Nigerian medical journal : journal of the Nigeria Medical Association 20110101
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Undernutrition among HIV-positive children in Dar es Salaam, Tanzania: antiretroviral therapy alone is not enough. BMC public health 20110101
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Impact of comorbidities and drug therapy on development of renal impairment in a predominantly African American and Hispanic HIV clinic population. HIV/AIDS (Auckland, N.Z.) 20110101
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Growth hormone and tesamorelin in the management of HIV-associated lipodystrophy. HIV/AIDS (Auckland, N.Z.) 20110101
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AtriplaR/anti-TB combination in TB/HIV patients. Drug in focus. BMC research notes 20110101
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Resistance patterns selected by nevirapine vs. efavirenz in HIV-infected patients failing first-line antiretroviral treatment: a bayesian analysis. PloS one 20110101
Which compound to select in lead optimization? Prospectively validated proteochemometric models guide preclinical development. PloS one 20110101
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Nevirapine induced exfoliative dermatitis in an HIV-infected patient. Indian journal of pharmacology 20110101
Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the male and female genital tract. Antiviral therapy 20110101
Correlation between lamivudine plasma concentrations and patient self-reported adherence to antiretroviral treatment in experienced HIV patients. Therapeutics and clinical risk management 20110101
Pharmacogenetic & pharmacokinetic biomarker for efavirenz based ARV and rifampicin based anti-TB drug induced liver injury in TB-HIV infected patients. PloS one 20110101
Cost-effectiveness analysis of initial HIV treatment under Italian guidelines. ClinicoEconomics and outcomes research : CEOR 20110101
Label-free electrochemical detection of the specific oligonucleotide sequence of dengue virus type 1 on pencil graphite electrodes. Sensors (Basel, Switzerland) 20110101
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A multifaceted analysis of HIV-1 protease multidrug resistance phenotypes. BMC bioinformatics 20110101
In silico identification of structure requirement for novel thiazole and oxazole derivatives as potent fructose 1,6-bisphosphatase inhibitors. International journal of molecular sciences 20110101
Intensification of antiretroviral therapy with a CCR5 antagonist in patients with chronic HIV-1 infection: effect on T cells latently infected. PloS one 20110101
Risk factors for default from tuberculosis treatment in HIV-infected individuals in the state of Pernambuco, Brazil: a prospective cohort study. BMC infectious diseases 20110101
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Emergence of HBV resistance to lamivudine (3TC) in HIV/HBV co-infected patients in The Gambia, West Africa. BMC research notes 20110101
Estimating loss to follow-up in HIV-infected patients on antiretroviral therapy: the effect of the competing risk of death in Zambia and Switzerland. PloS one 20110101
Evaluation of cellular phenotypes implicated in immunopathogenesis and monitoring immune reconstitution inflammatory syndrome in HIV/leprosy cases. PloS one 20110101
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Comparative manufacture and cell-based delivery of antiretroviral nanoformulations. International journal of nanomedicine 20110101
Lipodystrophy in HIV patients: its challenges and management approaches. HIV/AIDS (Auckland, N.Z.) 20110101
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Artemether-Lumefantrine Combination Therapy for Treatment of Uncomplicated Malaria: The Potential for Complex Interactions with Antiretroviral Drugs in HIV-Infected Individuals. Malaria research and treatment 20110101
Disseminated infections due to Immune Reconstitution Inflammatory Syndrome after highly active antiretroviral therapy--report of 3 cases from Nigeria. The Pan African medical journal 20110101
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Undiagnosed HIV Presenting with Lymphoid Interstitial Pneumonitis. Case reports in infectious diseases 20110101
Syphilitic Aortic Aneurysm in a Young HIV-Infected Man: Case Presentation. Case reports in infectious diseases 20110101
Rilpivirine and complera: new first-line treatment options. BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation 20110101
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Simple, precise and accurate HPLC method of analysis for nevirapine suspension from human plasma. Indian journal of pharmaceutical sciences 20110101
Dissolution enhancement of efavirenz by solid dispersion and PEGylation techniques. International journal of pharmaceutical investigation 20110101
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A highly sensitive ultra performance liquid chromatography-tandem mass spectrometric (UPLC-MS/MS) technique for quantitation of protein free and bound efavirenz (EFV) in human seminal and blood plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101201
Changing baseline characteristics among patients in the China National Free Antiretroviral Treatment Program, 2002-09. International journal of epidemiology 20101201
Interview with Dr. Mark Cockett: current trends in screening for antiviral therapeutics. Interviewed by Nina N. Brahme and Devin J. Noblin. The Yale journal of biology and medicine 20101201
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The evolutionary analysis of emerging low frequency HIV-1 CXCR4 using variants through time--an ultra-deep approach. PLoS computational biology 20101201
Scaling up the 2010 World Health Organization HIV Treatment Guidelines in resource-limited settings: a model-based analysis. PLoS medicine 20101201
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A randomized factorial trial comparing 4 treatment regimens in treatment-naive HIV-infected persons with AIDS and/or a CD4 cell count <200 cells/μL in South Africa. The Journal of infectious diseases 20101115
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Exploration of piperidine-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-Phenyl derivatives with broad potency against resistant mutant viruses. Bioorganic & medicinal chemistry letters 20101015
Determination of salivary efavirenz by liquid chromatography coupled with tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015
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Decreased plasma efavirenz concentrations in a patient receiving rifabutin. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20101001
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Differential effects of efavirenz and lopinavir/ritonavir on human adipocyte differentiation, gene expression and release of adipokines and pro-inflammatory cytokines. Current HIV research 20101001
Safety and tolerability of lersivirine, a nonnucleoside reverse transcriptase inhibitor, during a 28-day, randomized, placebo-controlled, Phase I clinical study in healthy male volunteers. Clinical therapeutics 20101001
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Prevalence of mutations and determinants of genotypic resistance to etravirine (TMC125) in a large Italian resistance database (ARCA). HIV medicine 20100901
Abdominal tuberculosis: sonographic diagnosis and treatment response in HIV-positive adults in rural South Africa. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20100901
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Randomized comparison of renal effects, efficacy, and safety with once-daily abacavir/lamivudine versus tenofovir/emtricitabine, administered with efavirenz, in antiretroviral-naive, HIV-1-infected adults: 48-week results from the ASSERT study. Journal of acquired immune deficiency syndromes (1999) 20100901
N-alkylation of poloxamines modulates micellar assembly and encapsulation and release of the antiretroviral efavirenz. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20100901
Drug resistance is widespread among children who receive long-term antiretroviral treatment at a rural Tanzanian hospital. The Journal of antimicrobial chemotherapy 20100901
Haplotype structure of CYP2B6 and association with plasma efavirenz concentrations in a Chilean HIV cohort. The Journal of antimicrobial chemotherapy 20100901
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KI and WU polyomaviruses and CD4+ cell counts in HIV-1-infected patients, Italy. Emerging infectious diseases 20100901
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A less sensitive detector does not necessarily result in a less sensitive method: fast quantification of 13 antiretroviral analytes in plasma with liquid chromatography coupled with tandem mass spectrometry. Clinical chemistry and laboratory medicine 20100801
Methadone, buprenorphine, and street drug interactions with antiretroviral medications. Current HIV/AIDS reports 20100801
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Biaryl ethers as potent allosteric inhibitors of reverse transcriptase and its key mutant viruses: aryl substituted pyrazole as a surrogate for the pyrazolopyridine motif. Bioorganic & medicinal chemistry letters 20100801
No changes in efavirenz plasma concentrations in HIV-infected patients who switch from Stocrin to Atripla. Journal of acquired immune deficiency syndromes (1999) 20100801
Enhanced oxidative stress and increased mitochondrial mass during efavirenz-induced apoptosis in human hepatic cells. British journal of pharmacology 20100801
Using touchscreen electronic medical record systems to support and monitor national scale-up of antiretroviral therapy in Malawi. PLoS medicine 20100801
The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: a randomized controlled trial. PLoS medicine 20100801
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Low frequency of liver enzyme elevation in HIV-infected patients attending a large urban treatment centre in Uganda. International journal of STD & AIDS 20100801
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Efavirenz is associated with severe vitamin D deficiency and increased alkaline phosphatase. AIDS (London, England) 20100731
Isoniazid-associated hepatitis and antiretroviral drugs during tuberculosis prophylaxis in hiv-infected adults in Botswana. American journal of respiratory and critical care medicine 20100715
Discovery of piperidin-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-benzyl derivatives with broad potency against resistant mutant viruses. Bioorganic & medicinal chemistry letters 20100715
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Improved HIV and substance abuse treatment outcomes for released HIV-infected prisoners: the impact of buprenorphine treatment. Journal of urban health : bulletin of the New York Academy of Medicine 20100701
Disseminated bartonellosis presenting as neuroretinitis in a young adult with human immunodeficiency virus infection. The Pediatric infectious disease journal 20100701
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Response to first line HAART using CD4 cell counts experience in a university hospital in Kingston. The West Indian medical journal 20100701
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Using electronic drug monitor feedback to improve adherence to antiretroviral therapy among HIV-positive patients in China. AIDS and behavior 20100601
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Slow binding-tight binding interaction between benzimidazol-2-one inhibitors and HIV-1 reverse transcriptase containing the lysine 103 to asparagine mutation. Antiviral research 20100601
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Using mechanistic models to simulate comparative effectiveness trials of therapy and to estimate long-term outcomes in HIV care. Medical care 20100601
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Novel strategies in the use of lopinavir/ritonavir for the treatment of HIV infection in children. HIV/AIDS (Auckland, N.Z.) 20100101
An update on the use of Atripla in the treatment of HIV in the United States. HIV/AIDS (Auckland, N.Z.) 20100101
Role of etravirine in the management of treatment-experienced patients with human immunodeficiency virus type 1. HIV/AIDS (Auckland, N.Z.) 20100101
Profile of maraviroc: a CCR5 antagonist in the management of treatment-experienced HIV patients. HIV/AIDS (Auckland, N.Z.) 20100101
Long-term treatment of patients with HIV-1: the role of atazanavir. HIV/AIDS (Auckland, N.Z.) 20100101
New and emerging agents in the management of lipodystrophy in HIV-infected patients. HIV/AIDS (Auckland, N.Z.) 20100101
Histological effects of chronic administration of efavirenz on lateral geniculate body of adult Wistar rats. North American journal of medical sciences 20100101
Viremia, resuppression, and time to resistance in human immunodeficiency virus (HIV) subtype C during first-line antiretroviral therapy in South Africa. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20091215
Synthesis and biological evaluation of C-5 methyl substituted 4-arylthio and 4-aryloxy-3-Iodopyridin-2(1H)-one type anti-HIV agents. Journal of medicinal chemistry 20091210
Abacavir-lamivudine versus tenofovir-emtricitabine for initial HIV-1 therapy. The New England journal of medicine 20091203
Good neurocognitive performance measured by the international HIV dementia scale in early HIV-1 infection. Journal of acquired immune deficiency syndromes (1999) 20091201
Activity and molecular modeling of a new small molecule active against NNRTI-resistant HIV-1 mutants. European journal of medicinal chemistry 20091201
Low-frequency K103N strengthens the impact of transmitted drug resistance on virologic responses to first-line efavirenz or nevirapine-based highly active antiretroviral therapy. Journal of acquired immune deficiency syndromes (1999) 20091201
Synthesis, pharmacological and antiviral activity of 1,3-thiazepine derivatives. European journal of medicinal chemistry 20091201
New small-molecule inhibitor class targeting human immunodeficiency virus type 1 virion maturation. Antimicrobial agents and chemotherapy 20091201
Application of an allele-specific PCR to clinical HIV genotyping samples detects additional K103N mutations in both therapy naïve and experienced patients. Journal of medical virology 20091201
Validation of an electrospray ionization LC-MS/MS method for quantitative analysis of raltegravir, etravirine, and 9 other antiretroviral agents in human plasma samples. Therapeutic drug monitoring 20091201
Reversal of growth failure in HIV-infected Thai children treated with non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy. AIDS patient care and STDs 20091201
Satisfactory cross-cultural validity of the ACTG symptom distress module in HIV-1-infected antiretroviral-naive patients. Clinical trials (London, England) 20091201
Drug-drug interaction between itraconazole and the protease inhibitor lopinavir/ritonavir. The Annals of pharmacotherapy 20091201
Antiretroviral genotypic resistance mutations in HIV-1 infected Korean patients with virologic failure. Journal of Korean medical science 20091201
Early and late direct costs in a Southern African antiretroviral treatment programme: a retrospective cohort analysis. PLoS medicine 20091201
NanoART synthesis, characterization, uptake, release and toxicology for human monocyte-macrophage drug delivery. Nanomedicine (London, England) 20091201
Effect of efavirenz on high-density lipoprotein antioxidant properties in HIV-infected patients. British journal of clinical pharmacology 20091201
FDA notifications. Generic efavirenz capsules tentatively approved by FDA. AIDS alert 20091201
Antiretroviral therapy: new drugs, formulations, ideas, and strategies. Topics in HIV medicine : a publication of the International AIDS Society, USA 20091201
[Chronic abdominal pain and fever in an Ivoirian woman: Mycobacterium avium-intracellulare duodenitis in an AIDS patient in Abidjan, Cote d'Ivoire]. Medecine tropicale : revue du Corps de sante colonial 20091201
[Compulsory licensing of efavirenz in Brazil in 2007: contextualization]. Revista panamericana de salud publica = Pan American journal of public health 20091201
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[Etravirine: genetic barrier and resistance development]. Enfermedades infecciosas y microbiologia clinica 20091201
[Role of etravirine in combination antiretroviral therapy]. Enfermedades infecciosas y microbiologia clinica 20091201
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20091201
(S)-6-Chloro-4-cyclo-propyl-ethynyl-4-trifluoro-methyl-1H-3,1-benzoxazin-2(4H)-one. Acta crystallographica. Section E, Structure reports online 20091201
Mutation rates and intrinsic fidelity of retroviral reverse transcriptases. Viruses 20091201
Synthesis and biological evaluation of novel 2-(substituted phenylaminocarbonylmethylthio)-6-(2,6-dichlorobenzyl)-pyrimidin-4(3H)-ones as potent HIV-1 NNRTIs. Bioorganic & medicinal chemistry 20091115
Substituting nevirapine for efavirenz: risk factors for toxicity in nonnaive patients in a resource-constrained setting. AIDS (London, England) 20091113
Synthesis and anti-HIV activity evaluation of 2-(4-(naphthalen-2-yl)-1,2,3-thiadiazol-5-ylthio)-N-acetamides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors. European journal of medicinal chemistry 20091101
Sustained antiretroviral effect of raltegravir after 96 weeks of combination therapy in treatment-naive patients with HIV-1 infection. Journal of acquired immune deficiency syndromes (1999) 20091101
[Regimen simplification: lopinavir/ritonavir with or without efavirenz]. Enfermedades infecciosas y microbiologia clinica 20091101
Intracellular accumulation of efavirenz and nevirapine is independent of P-glycoprotein activity in cultured CD4 T cells and primary human lymphocytes. The Journal of antimicrobial chemotherapy 20091101
Efavirenz: a decade of clinical experience in the treatment of HIV. The Journal of antimicrobial chemotherapy 20091101
Synthesis of novel uracil non-nucleoside derivatives as potential reverse transcriptase inhibitors of HIV-1. Archiv der Pharmazie 20091101
Antiretroviral drug-resistant mutations at baseline and at time of failure of antiretroviral therapy in HIV type 1-coinfected TB patients. AIDS research and human retroviruses 20091101
A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans. British journal of clinical pharmacology 20091101
FDA notifications. FDA approves generic combination of efavirenz, lamivudine & tenofovir. AIDS alert 20091101
Drugs in traditional drug classes (nucleoside reverse transcriptase inhibitor/nonnucleoside reverse transcriptase inhibitor/protease inhibitors) with activity against drug-resistant virus (tipranavir, darunavir, etravirine). Current opinion in HIV and AIDS 20091101
Human immunodeficiency virus type 1 subtypes prevalence in central China. Yonsei medical journal 20091031
Efavirenz plasma concentrations did not predict cessation of therapy due to neuropsychiatric symptoms in a large randomized trial. AIDS (London, England) 20091023
CYP2B6, CYP2A6 and UGT2B7 genetic polymorphisms are predictors of efavirenz mid-dose concentration in HIV-infected patients. AIDS (London, England) 20091023
Pyrazole NNRTIs 4: selection of UK-453,061 (lersivirine) as a development candidate. Bioorganic & medicinal chemistry letters 20091015
[Acute renal failure and hypercalcemia in an AIDS patient on tenofovir and low-dose vitamin D therapy with immune reconstitution inflammatory syndrome]. Medizinische Klinik (Munich, Germany : 1983) 20091015
Antiretroviral compounds and cholesterol efflux from macrophages. Atherosclerosis 20091001
Discordance in HIV-1 viral loads and antiretroviral drug concentrations comparing semen and blood plasma. HIV medicine 20091001
Allele and genotype frequencies of cytochrome P450 2B6 gene in a Mongolian population. Drug metabolism and disposition: the biological fate of chemicals 20091001
Efavirenz dose reduction is safe in patients with high plasma concentrations and may prevent efavirenz discontinuations. Journal of acquired immune deficiency syndromes (1999) 20091001
Pharmacokinetics and safety of etravirine administered once or twice daily after 2 weeks treatment with efavirenz in healthy volunteers. Journal of acquired immune deficiency syndromes (1999) 20091001
Dissection of regenerating T-Cell responses against tuberculosis in HIV-infected adults sensitized by Mycobacterium tuberculosis. American journal of respiratory and critical care medicine 20091001
Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. Journal of acquired immune deficiency syndromes (1999) 20091001
Development of HIV-1 drug resistance through 144 weeks in antiretroviral-naïve subjects on emtricitabine, tenofovir disoproxil fumarate, and efavirenz compared with lamivudine/zidovudine and efavirenz in study GS-01-934. Journal of acquired immune deficiency syndromes (1999) 20091001
A comparison of HIV-1 drug susceptibility as provided by conventional phenotyping and by a phenotype prediction tool based on viral genotype. Journal of medical virology 20091001
A liquid chromatography-tandem mass spectrometry assay for quantification of nevirapine, indinavir, atazanavir, amprenavir, saquinavir, ritonavir, lopinavir, efavirenz, tipranavir, darunavir and maraviroc in the plasma of patients infected with HIV. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091001
Pyrazole NNRTIs 1: design and initial optimisation of a novel template. Bioorganic & medicinal chemistry letters 20091001
Pyrazole NNRTIs 3: optimisation of physicochemical properties. Bioorganic & medicinal chemistry letters 20091001
Task shifting for scale-up of HIV care: evaluation of nurse-centered antiretroviral treatment at rural health centers in Rwanda. PLoS medicine 20091001
FDA notifications. Generic efavirenz/emtricitabine/fenofovir has tentative approval. AIDS alert 20091001
A prospective, observational cohort study to elicit adverse effects of antiretroviral agents in a remote resource-restricted tribal population of Chhattisgarh. Indian journal of pharmacology 20091001
Effectiveness of highly active antiretroviral therapy (HAART) used concomitantly with rifampicin in patients with tuberculosis and AIDS. The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20091001
Reply to 'kidney transplantation in a patient with HIV disease'. Indian journal of nephrology 20091001
Opsoclonus-myoclonus syndrome and HIV-infection. Journal of the neurological sciences 20090915
CYP2B6 variants and plasma efavirenz concentrations during antiretroviral therapy in Port-au-Prince, Haiti. The Journal of infectious diseases 20090915
Raltegravir: a new choice in HIV and new chances for research. Lancet (London, England) 20090905
Safety and efficacy of raltegravir-based versus efavirenz-based combination therapy in treatment-naive patients with HIV-1 infection: a multicentre, double-blind randomised controlled trial. Lancet (London, England) 20090905
Extreme variability in the formation of chlorpyrifos oxon (CPO) in patients poisoned by chlorpyrifos (CPF). Biochemical pharmacology 20090901
CYP2B6 G516T genotyping in a UK cohort of HIV-positive patients: polymorphism frequency and influence on efavirenz discontinuation. HIV medicine 20090901
Glucuronidation of the antiretroviral drug efavirenz by UGT2B7 and an in vitro investigation of drug-drug interaction with zidovudine. Drug metabolism and disposition: the biological fate of chemicals 20090901
The in vivo response of novel buprenorphine metabolites, M1 and M3, to antiretroviral inducers and inhibitors of buprenorphine metabolism. Basic & clinical pharmacology & toxicology 20090901
Design, synthesis, and SAR of naphthyl-substituted Diarylpyrimidines as non-nucleoside inhibitors of HIV-1 reverse transcriptase. ChemMedChem 20090901
Synthesis and anti-HIV-1 activity of 1-substiuted 6-(3-cyanobenzoyl) and [(3-cyanophenyl)fluoromethyl]-5-ethyl-uracils. Archiv der Pharmazie 20090901
1,2,3-Selenadiazole thioacetanilides: synthesis and anti-HIV activity evaluation. Bioorganic & medicinal chemistry 20090901
Predictors of virologic failure and genotypic resistance mutation patterns in thai children receiving non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy. The Pediatric infectious disease journal 20090901
Substrate specificity, regulation, and polymorphism of human cytochrome P450 2B6. Current drug metabolism 20090901
The history of antiretrovirals: key discoveries over the past 25 years. Reviews in medical virology 20090901
Changes in cognition during antiretroviral therapy: comparison of 2 different ranking systems to measure antiretroviral drug efficacy on HIV-associated neurocognitive disorders. Journal of acquired immune deficiency syndromes (1999) 20090901
[Efficacy and safety of TAM-sparing antiretroviral regimens in naïve HIV-positive patients]. Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20090901
Long-term effectiveness and safety outcomes in HIV-1-infected patients after a median time of 6 years on nevirapine. Current HIV research 20090901
Loss of bone mineral density after antiretroviral therapy initiation, independent of antiretroviral regimen. Journal of acquired immune deficiency syndromes (1999) 20090815
A randomized comparative trial of continued zidovudine/lamivudine or replacement with tenofovir disoproxil fumarate/emtricitabine in efavirenz-treated HIV-1-infected individuals. Journal of acquired immune deficiency syndromes (1999) 20090815
Design, synthesis, and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents. Bioorganic & medicinal chemistry 20090815
Novel 1,2,3-thiadiazole derivatives as HIV-1 NNRTIs with improved potency: Synthesis and preliminary SAR studies. Bioorganic & medicinal chemistry 20090815
Synthesis and biological evaluation of imidazole thioacetanilides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors. Bioorganic & medicinal chemistry 20090815
Stepped-dose versus full-dose efavirenz for HIV infection and neuropsychiatric adverse events: a randomized trial. Annals of internal medicine 20090804
Comparison of side effects with 2 doses of the HIV drug efavirenz. Annals of internal medicine 20090804
The relationships of ABCB1 3435C>T and CYP2B6 516G>T with high-density lipoprotein cholesterol in HIV-infected patients receiving Efavirenz. Clinical pharmacology and therapeutics 20090801
Human immunodeficiency virus: 25 years of diagnostic and therapeutic strategies and their impact on hepatitis B and C virus. Medical microbiology and immunology 20090801
Pharmacokinetics of plasma efavirenz and CYP2B6 polymorphism in southern Chinese. Therapeutic drug monitoring 20090801
Synthesis, antiviral activity and molecular modeling of oxoquinoline derivatives. Bioorganic & medicinal chemistry 20090801
Effects of oral posaconazole on the pharmacokinetics of atazanavir alone and with ritonavir or with efavirenz in healthy adult volunteers. Journal of acquired immune deficiency syndromes (1999) 20090801
96-Week MERIT ES analysis shows efficacy of Celsentri=Selzentry. AIDS patient care and STDs 20090801
Raltegravir as effective as efavirenz in 144-week data. AIDS patient care and STDs 20090801
Nucleoside reverse transcriptase inhibitor-sparing regimen (nonnucleoside reverse transcriptase inhibitor + protease inhibitor) was more likely associated with resistance comparing to nonnucleoside reverse transcriptase inhibitor or protease inhibitor + nucleoside reverse transcriptase inhibitor in the randomized ANRS 121 trial. AIDS (London, England) 20090731
Rapid method for the quantitative determination of efavirenz in human plasma. Journal of pharmaceutical and biomedical analysis 20090712
A combination drug of abacavir-lamivudine-zidovudine (Trizivir) for treating HIV infection and AIDS. The Cochrane database of systematic reviews 20090708
Cytotoxicological analysis of a gp120 binding aptamer with cross-clade human immunodeficiency virus type 1 entry inhibition properties: comparison to conventional antiretrovirals. Antimicrobial agents and chemotherapy 20090701
A randomized trial of two-drug versus three-drug tenofovir-containing maintenance regimens in virologically controlled HIV-1 patients. The Journal of antimicrobial chemotherapy 20090701
The effect of individual antiretroviral drugs on body composition in HIV-infected persons initiating highly active antiretroviral therapy. Journal of acquired immune deficiency syndromes (1999) 20090701
Influence of the cytochrome P450 2B6 genotype on population pharmacokinetics of efavirenz in human immunodeficiency virus patients. Antimicrobial agents and chemotherapy 20090701
Validation and clinical application of a high performance liquid chromatography tandem mass spectrometry (LC-MS/MS) method for the quantitative determination of 10 anti-retrovirals in human peripheral blood mononuclear cells. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090701
Rilpivirine: a novel non-nucleoside reverse transcriptase inhibitor. Expert opinion on investigational drugs 20090701
Artemisinin--a possible CYP2B6 probe substrate? Biopharmaceutics & drug disposition 20090701
Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection. PLoS medicine 20090701
New pyridinone derivatives as potent HIV-1 nonnucleoside reverse transcriptase inhibitors. Journal of medicinal chemistry 20090625
Efavirenz treatment and false-positive results in benzodiazepine screening tests. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090615
Efavirenz and nevirapine interactions with rifampicin: resolving the dilemmas? Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090615
A randomized trial comparing plasma drug concentrations and efficacies between 2 nonnucleoside reverse-transcriptase inhibitor-based regimens in HIV-infected patients receiving rifampicin: the N2R Study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090615
Effects of nevirapine and efavirenz on HDL cholesterol levels and reverse cholesterol transport in mice. Atherosclerosis 20090601
Adherence to first-line antiretroviral therapy affects non-virologic outcomes among patients on treatment for more than 12 months in Lusaka, Zambia. International journal of epidemiology 20090601
Model-based approach to characterize efavirenz autoinduction and concurrent enzyme induction with carbamazepine. Antimicrobial agents and chemotherapy 20090601
Regulation of human vitamin D(3) 25-hydroxylases in dermal fibroblasts and prostate cancer LNCaP cells. Molecular pharmacology 20090601
Antiviral activity of MK-4965, a novel nonnucleoside reverse transcriptase inhibitor. Antimicrobial agents and chemotherapy 20090601
Population pharmacokinetics of ritonavir-boosted atazanavir in HIV-infected patients and healthy volunteers. The Journal of antimicrobial chemotherapy 20090601
The nucleoside backbone affects durability of efavirenz- or nevirapine-based highly active antiretroviral therapy in antiretroviral-naive individuals. Journal of acquired immune deficiency syndromes (1999) 20090601
Simplification of antiretroviral therapy to a single-tablet regimen consisting of efavirenz, emtricitabine, and tenofovir disoproxil fumarate versus unmodified antiretroviral therapy in virologically suppressed HIV-1-infected patients. Journal of acquired immune deficiency syndromes (1999) 20090601
Maraviroc: perspectives for use in antiretroviral-naive HIV-1-infected patients. The Journal of antimicrobial chemotherapy 20090601
HIV infection and the central nervous system: a primer. Neuropsychology review 20090601
Metabolic outcomes in a randomized trial of nucleoside, nonnucleoside and protease inhibitor-sparing regimens for initial HIV treatment. AIDS (London, England) 20090601
Drug resistance in the Chinese National Pediatric Highly Active Antiretroviral Therapy Cohort: implications for paediatric treatment in the developing world. International journal of STD & AIDS 20090601
Efavirenz and bone health. AIDS (London, England) 20090601
Interaction of Ginkgo biloba with efavirenz. AIDS (London, England) 20090601
Tapping into combination pills for HIV. Nature reviews. Drug discovery 20090601
How much fat loss is needed for lipoatrophy to become clinically evident? AIDS research and human retroviruses 20090601
Pattern and predictors of immunologic recovery in human immunodeficiency virus-infected children receiving non-nucleoside reverse transcriptase inhibitor-based highly active antiretroviral therapy. The Pediatric infectious disease journal 20090601
Efavirenz + emtricitabine + tenofovir: new combination. HIV infection: do not modify ongoing therapy just to use one less tablet. Better adherence than with separate dosing has not been demonstrated, while reduced efficacy is plausible. Prescrire international 20090601
Evaluation of HIV/AIDS patients' knowledge on antiretroviral drugs. The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20090601
The transport of anti-HIV drugs across blood-CNS interfaces: summary of current knowledge and recommendations for further research. Antiviral research 20090501
Improvement in lipid profiles over 6 years of follow-up in adults with AIDS and immune reconstitution. HIV medicine 20090501
Pharmacogenetics-based population pharmacokinetic analysis of efavirenz in HIV-1-infected individuals. Clinical pharmacology and therapeutics 20090501
Response to zidovudine/didanosine-containing combination antiretroviral therapy among HIV-1 subtype C-infected adults in Botswana: two-year outcomes from a randomized clinical trial. Journal of acquired immune deficiency syndromes (1999) 20090501
Long-term efficacy and safety of TDM-assisted combination of voriconazole plus efavirenz in an AIDS patient with cryptococcosis and liver cirrhosis. The Annals of pharmacotherapy 20090501
Synthesis and studies of new 2-(coumarin-4-yloxy)-4,6-(substituted)-S-triazine derivatives as potential anti-HIV agents. Archiv der Pharmazie 20090501
Leishmania infantum amastigotes enhance HIV-1 production in cocultures of human dendritic cells and CD4 T cells by inducing secretion of IL-6 and TNF-alpha. PLoS neglected tropical diseases 20090501
[Tolerance study of a triple first-line antiretroviral combination zidovudine, lamivudine and efavirenz in Dakar, Senegal]. Bulletin de la Societe de pathologie exotique (1990) 20090501
High rates of regimen change due to drug toxicity among a cohort of South Indian adults with HIV infection initiated on generic, first-line antiretroviral treatment. The Journal of the Association of Physicians of India 20090501
Heart Disease in Patients with HIV/AIDS-An Emerging Clinical Problem. Current cardiology reviews 20090501
[Medication change due to side effects or possible long-term complications. Side effect management with vision]. MMW Fortschritte der Medizin 20090430
[One year with Atripla. Changeover to complete HIV therapy in a single tablet has proven successful]. MMW Fortschritte der Medizin 20090430
Antiretroviral drug susceptibility among drug-naive adults with recent HIV infection in Rakai, Uganda. AIDS (London, England) 20090427
Screening and monitoring antiretrovirals and antivirals in the serum of acquired immunodeficiency syndrome patients by micellar liquid chromatography. Journal of chromatography. A 20090417
Voltammetric studies on the HIV-1 inhibitory drug Efavirenz: the interaction between dsDNA and drug using electrochemical DNA biosensor and adsorptive stripping voltammetric determination on disposable pencil graphite electrode. Biosensors & bioelectronics 20090415
Effect of rifampicin on efavirenz pharmacokinetics in HIV-infected children with tuberculosis. Journal of acquired immune deficiency syndromes (1999) 20090415
The combined effect of modern highly active antiretroviral therapy regimens and adherence on mortality over time. Journal of acquired immune deficiency syndromes (1999) 20090415
Proinflammatory cytokine changes in clinically stable, virologically suppressed, HIV-infected patients switching from protease inhibitors to abacavir. Journal of acquired immune deficiency syndromes (1999) 20090415
Maraviroc: a coreceptor CCR5 antagonist for management of HIV infection. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090415
Nonnucleoside reverse transcriptase inhibitor pharmacokinetics in a large unselected cohort of HIV-infected women. Journal of acquired immune deficiency syndromes (1999) 20090415
Indolylarylsulfones bearing natural and unnatural amino acids. Discovery of potent inhibitors of HIV-1 non-nucleoside wild type and resistant mutant strains reverse transcriptase and coxsackie B4 virus. Journal of medicinal chemistry 20090409
Effectiveness and safety of simplification from tenofovir-lamivudine (TDF-3TC) to tenofovir-emtricitabine (TDF-FTC) co-formulation (Truvada) in virologically suppressed HIV-infected patients on HAART. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20090401
Simultaneous quantification of a non-nucleoside reverse transcriptase inhibitor efavirenz, a nucleoside reverse transcriptase inhibitor emtricitabine and a nucleotide reverse transcriptase inhibitor tenofovir in plasma by liquid chromatography positive ion electrospray tandem mass spectrometry. Biomedical chromatography : BMC 20090401
Novel modifications in the series of O-(2-phthalimidoethyl)-N-substituted thiocarbamates and their ring-opened congeners as non-nucleoside HIV-1 reverse transcriptase inhibitors. European journal of medicinal chemistry 20090401
Anti-HIV drugs: 25 compounds approved within 25 years after the discovery of HIV. International journal of antimicrobial agents 20090401
Viral dynamics of hepatitis B virus DNA in human immunodeficiency virus-1-hepatitis B virus coinfected individuals: similar effectiveness of lamivudine, tenofovir, or combination therapy. Hepatology (Baltimore, Md.) 20090401
Association of high T allele frequency of CYP2B6 G516T polymorphism among ethnic south Indian HIV-infected patients with elevated plasma efavirenz and nevirapine. The Journal of antimicrobial chemotherapy 20090401
Raltegravir: the first HIV type 1 integrase inhibitor. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090401
In vivo analysis of efavirenz metabolism in individuals with impaired CYP2A6 function. Pharmacogenetics and genomics 20090401
Synthesis and biological evaluation of N4-(hetero)arylsulfonylquinoxalinones as HIV-1 reverse transcriptase inhibitors. Bioorganic & medicinal chemistry 20090401
Elite suppressor-derived HIV-1 envelope glycoproteins exhibit reduced entry efficiency and kinetics. PLoS pathogens 20090401
Therapeutic effects of Nigella sativa on chronic HAART-induced hyperinsulinemia in rats. Canadian journal of physiology and pharmacology 20090401
CYP2B6 (c.516G-->T) and CYP2A6 (*9B and/or *17) polymorphisms are independent predictors of efavirenz plasma concentrations in HIV-infected patients. British journal of clinical pharmacology 20090401
The RNA polymerase dictates ORF1 requirement and timing of LINE and SINE retrotransposition. PLoS genetics 20090401
[Establishment of pharmacological evaluation system for non-nucleoside reverse-transcriptase inhibitors resistant HIV-1]. Yao xue xue bao = Acta pharmaceutica Sinica 20090401
Metabolic effects associated to the highly active antiretroviral therapy (HAART) in AIDS patients. The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20090401
Characterization of vaginal transmission of a simian human immunodeficiency virus (SHIV) encoding the reverse transcriptase gene from HIV-1 in Chinese rhesus macaques. Virology 20090330
Efavirenz dose reduction to 200 mg once daily in a patient treated with rifampicin. AIDS (London, England) 20090327
New synthetic technologies for the construction of heterocycles and tryptamines. Journal of the American Chemical Society 20090318
Associations between CYP2B6 polymorphisms and pharmacokinetics after a single dose of nevirapine or efavirenz in African americans. The Journal of infectious diseases 20090315
Decreased susceptibility of the cytochrome P450 2B6 variant K262R to inhibition by several clinically important drugs. Drug metabolism and disposition: the biological fate of chemicals 20090301
Preclinical evaluation of GS-9160, a novel inhibitor of human immunodeficiency virus type 1 integrase. Antimicrobial agents and chemotherapy 20090301
CYP2B6 G516T polymorphism but not rifampin coadministration influences steady-state pharmacokinetics of efavirenz in human immunodeficiency virus-infected patients in South India. Antimicrobial agents and chemotherapy 20090301
Physicochemical characterization of efavirenz-cyclodextrin inclusion complexes. AAPS PharmSciTech 20090301
Ultrasensitive assessment of residual HIV viraemia in HAART-treated patients with persistently undetectable plasma HIV-RNA: a cross-sectional evaluation. Journal of medical virology 20090301
A paediatric case of acute liver failure associated with efavirenz-based highly active antiretroviral therapy and effective use of raltegravir in combination antiretroviral treatment after liver transplantation. The Journal of antimicrobial chemotherapy 20090301
Influence of liver fibrosis stage on plasma levels of efavirenz in HIV-infected patients with chronic hepatitis B or C. The Journal of antimicrobial chemotherapy 20090301
Etravirine and rilpivirine: nonnucleoside reverse transcriptase inhibitors with activity against human immunodeficiency virus type 1 strains resistant to previous nonnucleoside agents. Pharmacotherapy 20090301
Predicting factors for unsuccessful switching from nevirapine to efavirenz in HIV-infected patients who developed nevirapine-associated skin rash. International journal of STD & AIDS 20090301
Safety and efficacy of nevirapine- and efavirenz-based antiretroviral treatment in adults treated for TB-HIV co-infection in Botswana. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20090301
Timing the emergence of resistance to anti-HIV drugs with large genetic barriers. PLoS computational biology 20090301
FDA notifications. Efavirenz 100 mg scored tablets approved for pediatric treatment. AIDS alert 20090301
Isentress equal to Sustiva in first line therapy. Project Inform perspective 20090301
Hyperhidrosis in association with efavirenz. AIDS patient care and STDs 20090301
Specific targeting of highly conserved residues in the HIV-1 reverse transcriptase primer grip region. 2. Stereoselective interaction to overcome the effects of drug resistant mutations. Journal of medicinal chemistry 20090226
Novel indazole non-nucleoside reverse transcriptase inhibitors using molecular hybridization based on crystallographic overlays. Journal of medicinal chemistry 20090226
Antiretroviral therapy and congenital abnormalities in infants born to HIV-infected women in the UK and Ireland, 1990-2007. AIDS (London, England) 20090220
Discovery of chiral cyclopropyl dihydro-alkylthio-benzyl-oxopyrimidine (S-DABO) derivatives as potent HIV-1 reverse transcriptase inhibitors with high activity against clinically relevant mutants. Journal of medicinal chemistry 20090212
Efavirenz Mannich bases: synthesis, anti-HIV and antitubercular activities. Journal of enzyme inhibition and medicinal chemistry 20090201
Low prevalence of insulin resistance among HIV-infected children receiving nonnucleoside reverse transcriptase inhibitor-based highly active antiretroviral therapy in Thailand. HIV medicine 20090201
Inhibition of human immunodeficiency virus type 1 infection by the candidate microbicide dapivirine, a nonnucleoside reverse transcriptase inhibitor. Antimicrobial agents and chemotherapy 20090201
Structural modifications of DAPY analogues with potent anti-HIV-1 activity. ChemMedChem 20090201
Steady-state pharmacokinetics of lopinavir/ritonavir in combination with efavirenz in human immunodeficiency virus-infected pediatric patients. The Pediatric infectious disease journal 20090201
A prospective study evaluating clinical outcomes and costs of three NNRTI-based HAART regimens in Kerala, India. Journal of clinical pharmacy and therapeutics 20090201
Head-to-head comparison of two first-line regimens and an NRTI-sparing regimen for initial therapy of HIV-1 infection: what should we start? Current HIV/AIDS reports 20090201
Pharmacologic aspects of new antiretroviral drugs. Current HIV/AIDS reports 20090201
Warfarin-antiretroviral interactions. The Annals of pharmacotherapy 20090201
Pregnancy among HIV-infected refugees in Rhode Island. AIDS care 20090201
Induction of multiple drug transporters by efavirenz. Journal of pharmacological sciences 20090201
[Atazanavir-induced nephrolithiasis]. Enfermedades infecciosas y microbiologia clinica 20090201
Pharmacokinetic interaction between efavirenz and ketoconazole in rats. Xenobiotica; the fate of foreign compounds in biological systems 20090201
Role of NEDD8 in HIV-associated lipodystrophy. Differentiation; research in biological diversity 20090201
Successful genotype-tailored treatment with small-dose efavirenz. AIDS (London, England) 20090128
Mutations at human immunodeficiency virus type 1 reverse transcriptase tryptophan repeat motif attenuate the inhibitory effect of efavirenz on virus production. Virology 20090120
Minority quasispecies of drug-resistant HIV-1 that lead to early therapy failure in treatment-naive and -adherent patients. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090115
Efavirenz-induced osteomalacia. AIDS (London, England) 20090114
Non-nucleoside HIV-1 reverse transcriptase inhibitors di-halo-indolyl aryl sulfones achieve tight binding to drug-resistant mutants by targeting the enzyme-substrate complex. Antiviral research 20090101
Effectiveness and safety of didanosine, lamivudine and efavirenz versus zidovudine, lamivudine and efavirenz for the initial treatment of HIV-infected patients from the Spanish VACH cohort. The Journal of antimicrobial chemotherapy 20090101
Quantification of 8 HIV-protease inhibitors and 2 nonnucleoside reverse transcriptase inhibitors by ultra-performance liquid chromatography with diode array detection. Clinical chemistry 20090101
The effects of Thiazolidinediones on metabolic complications and Lipodystrophy in HIV-infected patients. PPAR research 20090101
Antiretroviral-related adipocyte dysfunction and lipodystrophy in HIV-infected patients: Alteration of the PPARγ-dependent pathways. PPAR research 20090101
Human cyclin T1 expression ameliorates a T-cell-specific transcriptional limitation for HIV in transgenic rats, but is not sufficient for a spreading infection of prototypic R5 HIV-1 strains ex vivo. Retrovirology 20090101
Survey of physician knowledge regarding antiretroviral medications in hospitalized HIV-infected patients. Journal of the International AIDS Society 20090101
Facilitated monocyte-macrophage uptake and tissue distribution of superparmagnetic iron-oxide nanoparticles. PloS one 20090101
Prescribing and using self-injectable antiretrovirals: how concordant are physician and patient perspectives? AIDS research and therapy 20090101
Clinical deterioration during antitubercular treatment at a district hospital in South Africa: the importance of drug resistance and AIDS defining illnesses. PloS one 20090101
Development and evaluation of a clinical algorithm to monitor patients on antiretrovirals in resource-limited settings using adherence, clinical and CD4 cell count criteria. Journal of the International AIDS Society 20090101
Raltegravir, elvitegravir, and metoogravir: the birth of 'me-too' HIV-1 integrase inhibitors. Retrovirology 20090101
Emergence of primary NNRTI resistance mutations without antiretroviral selective pressure in a HAART-treated child. PloS one 20090101
Absence of a relation between efavirenz plasma concentrations and toxicity-driven efavirenz discontinuations in the EuroSIDA study. Antiviral therapy 20090101
Is PPARγ a prospective player in HIV-1-associated bone disease? PPAR research 20090101
A randomized, controlled trial of initial anti-retroviral therapy with abacavir/lamivudine/zidovudine twice-daily compared to atazanavir once-daily with lamivudine/zidovudine twice-daily in HIV-infected patients over 48 weeks (ESS100327, the ACTION Study). AIDS research and therapy 20090101
Effects of first-line use of nucleoside analogues, efavirenz, and ritonavir-boosted protease inhibitors on lipid levels. HIV clinical trials 20090101
HIV care and treatment factors associated with improved survival during TB treatment in Thailand: an observational study. BMC infectious diseases 20090101
Physical and emotional health outcomes after 12 months of public-sector antiretroviral treatment in the Free State Province of South Africa: a longitudinal study using structural equation modelling. BMC public health 20090101
Efficacy and safety of darunavir and etravirine in an antiretroviral multi-experienced youth with vertically HIV-1 infection. European journal of medical research 20090101
Rifampin pharmacokinetics in children, with and without human immunodeficiency virus infection, hospitalized for the management of severe forms of tuberculosis. BMC medicine 20090101
Quality of life and the impact of drug toxicities in a South African community-based antiretroviral programme. Journal of the International AIDS Society 20090101
Neurologic complications of HIV disease and their treatment. Topics in HIV medicine : a publication of the International AIDS Society, USA 20090101
TLR2 and TLR4 triggering exerts contrasting effects with regard to HIV-1 infection of human dendritic cells and subsequent virus transfer to CD4+ T cells. Retrovirology 20090101
Reducing stillbirths: prevention and management of medical disorders and infections during pregnancy. BMC pregnancy and childbirth 20090101
Mutations in the thumb-connection and RNase H domain of HIV type-1 reverse transcriptase of antiretroviral treatment-experienced patients. Antiviral therapy 20090101
Constraints on the dominant mechanism for HIV viral dynamics in patients on raltegravir. Antiviral therapy 20090101
Evolution of drug resistance after virological failure of a first-line highly active antiretroviral therapy regimen in Uganda. Antiviral therapy 20090101
Role of atazanavir in the treatment of HIV infection. Therapeutics and clinical risk management 20090101
The triple combination of tenofovir, emtricitabine and efavirenz shows synergistic anti-HIV-1 activity in vitro: a mechanism of action study. Retrovirology 20090101
Emtricitabine/tenofovir disoproxil fumarate: in combination with a protease inhibitor in HIV-1 infection. Drugs 20090101
Plasma efavirenz concentrations and the association with CYP2B6-516G >T polymorphism in HIV-infected Thai children. Antiviral therapy 20090101
Resistance profiles after different periods of exposure to a first-line antiretroviral regimen in a Cameroonian cohort of HIV type-1-infected patients. Antiviral therapy 20090101
Zidovudine/lamivudine for HIV-1 infection contributes to limb fat loss. PloS one 20090101
Risk factors for virological failure and subtherapeutic antiretroviral drug concentrations in HIV-positive adults treated in rural northwestern Uganda. BMC infectious diseases 20090101
Adrenal suppression due to an interaction between ritonavir and injected triamcinolone: a case report. AIDS research and therapy 20090101
Comparison of brachial and carotid artery ultrasound for assessing extent of subclinical atherosclerosis in HIV: a prospective cohort study. AIDS research and therapy 20090101
Neuropsychiatric symptoms associated with efavirenz: prevalence, correlates, and management. A neurobehavioral review. AIDS reviews 20090101
Emerging role of integrase inhibitors in the management of treatment-experienced patients with HIV infection. Therapeutics and clinical risk management 20090101
Switch from a ZDV/3TC-based regimen to a completely once daily (QD) regimen of emtricitabine/tenofovir DF fixed dose combination plus a third QD agent (SONETT). European journal of medical research 20090101
Pregnancy outcomes among HIV-infected women undergoing antiretroviral therapy. The open AIDS journal 20090101
Serum lipid profiles among patients initiating ritonavir-boosted atazanavir versus efavirenz-based regimens. AIDS research and therapy 20090101
Low-abundance HIV drug-resistant viral variants in treatment-experienced persons correlate with historical antiretroviral use. PloS one 20090101
Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection. PloS one 20090101
Reduction of the HIV-1 reservoir in resting CD4+ T-lymphocytes by high dosage intravenous immunoglobulin treatment: a proof-of-concept study. AIDS research and therapy 20090101
Effect of Immunomodulating Adjuvant Dzherelo (Immunoxel) in HIV Infected Patients Receiving Standard Antiretroviral Therapy. The open virology journal 20090101
The y271 and i274 amino acids in reverse transcriptase of human immunodeficiency virus-1 are critical to protein stability. PloS one 20090101
Virological efficacy and emergence of drug resistance in adults on antiretroviral treatment in rural Tanzania. BMC infectious diseases 20090101
Tetraspanins regulate cell-to-cell transmission of HIV-1. Retrovirology 20090101
Characterization of the patterns of drug-resistance mutations in newly diagnosed HIV-1 infected patients naïve to the antiretroviral drugs. BMC infectious diseases 20090101
Early initiation of antiretroviral therapy results in decreased morbidity and mortality among patients with TB and HIV. Journal of the International AIDS Society 20090101
High prevalence of undiagnosed chronic kidney disease among at-risk population in Kinshasa, the Democratic Republic of Congo. BMC nephrology 20090101
Clinical factors associated with plasma F2-isoprostane levels in HIV-infected adults. HIV clinical trials 20090101
A model and risk score for predicting nevirapine-associated rash among HIV-infected patients: in settings of low CD4 cell counts and resource limitation. The open AIDS journal 20090101
HIV-1 resistance to first- and second-generation non-nucleoside reverse transcriptase inhibitors. AIDS reviews 20090101
Mortality and loss-to-follow-up during the pre-treatment period in an antiretroviral therapy programme under normal health service conditions in Uganda. BMC public health 20090101
Isolation and characterization of a replication-competent molecular clone of an HIV-1 circulating recombinant form (CRF33_01B). PloS one 20090101
Bosentan in the treatment of pulmonary arterial hypertension with the focus on the mildly symptomatic patient. Vascular health and risk management 20090101
Excellent outcomes among HIV+ children on ART, but unacceptably high pre-ART mortality and losses to follow-up: a cohort study from Cambodia. BMC pediatrics 20090101
Effect of rifampicin-based antitubercular therapy and the cytochrome P450 2B6 516G>T polymorphism on efavirenz concentrations in adults in South Africa. Antiviral therapy 20090101
Short-term randomized proof-of-principle trial of TMC278 in patients with HIV type-1 who have previously failed antiretroviral therapy. Antiviral therapy 20090101
Pharmacotherapy of pediatric and adolescent HIV infection. Therapeutics and clinical risk management 20090101
Managing treatment-experienced pediatric and adolescent HIV patients: role of darunavir. Therapeutics and clinical risk management 20090101
Five-year follow-up of children with perinatal HIV-1 infection receiving early highly active antiretroviral therapy. BMC infectious diseases 20090101
Monitoring virologic responses to antiretroviral therapy in HIV-infected adults in Kenya: evaluation of a low-cost viral load assay. PloS one 20090101
Renal impairment in a rural African antiretroviral programme. BMC infectious diseases 20090101
Observational study to evaluate clinical outcomes after first-line efavirenz-or lopinavir-ritonavir-based HAART in treatment-naive patients. Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20090101
Adverse drug reactions to nonnucleoside reverse transcriptase inhibitor-based antiretroviral regimen: a 24-week prospective study. Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20090101
Antiretroviral therapy initiation before, during, or after pregnancy in HIV-1-infected women: maternal virologic, immunologic, and clinical response. PloS one 20090101
Tenofovir-emtricitabine-efavirenz in HIV-I-infected adults in Senegal: a 96-week pilot trial in treatment-naive patients. Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20090101
Comparison of 3-drug versus 4-drug and PI versus non-PI combinations as initial HAART: experience from 1998 to 2007. Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20090101
Evidence for limited genetic compartmentalization of HIV-1 between lung and blood. PloS one 20090101
Brazilian Network for HIV Drug Resistance Surveillance: a survey of individuals recently diagnosed with HIV. Journal of the International AIDS Society 20090101
Perinatal acquisition of drug-resistant HIV-1 infection: mechanisms and long-term outcome. Retrovirology 20090101
[Budget impact of a set-dose combination of efavirenz-emtricitabine-tenofovir in the treatment of patients infected with HIV-1]. Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20090101
Early outcomes of MDR-TB treatment in a high HIV-prevalence setting in Southern Africa. PloS one 20090101
The risk of virologic failure decreases with duration of HIV suppression, at greater than 50% adherence to antiretroviral therapy. PloS one 20090101
Drugs associated with more suicidal ideations are also associated with more suicide attempts. PloS one 20090101
XVII International AIDS Conference: From Evidence to Action - Clinical and biomedical prevention science. Journal of the International AIDS Society 20090101
XVII International AIDS Conference: From Evidence to Action - AIDS 2008 and the global response to AIDS. Journal of the International AIDS Society 20090101
Virological and immunological responses to efavirenz or boosted lopinavir as first-line therapy for patients with HIV. Antiviral therapy 20090101
The impact of combination antiretroviral therapy and its interruption on anxiety, stress, depression and quality of life in Thai patients. The open AIDS journal 20090101
Influence of non-nucleoside reverse transcriptase inhibitors (efavirenz and nevirapine) on the pharmacodynamic activity of gliclazide in animal models. Diabetology & metabolic syndrome 20090101
Whole body bone scintigraphy in tenofovir-related osteomalacia: a case report. Journal of medical case reports 20090101
High molecular weight form of adiponectin in antiretroviral drug-induced dyslipidemia in HIV-infected Japanese individuals based on in vivo and in vitro analyses. Internal medicine (Tokyo, Japan) 20090101
Barriers to the care of HIV-infected children in rural Zambia: a cross-sectional analysis. BMC infectious diseases 20090101
Immune control of HIV-1 infection after therapy interruption: immediate versus deferred antiretroviral therapy. BMC infectious diseases 20090101
HLA-Cw*04 allele associated with nevirapine-induced rash in HIV-infected Thai patients. AIDS research and therapy 20090101
Five-year follow up of genotypic resistance patterns in HIV-1 subtype C infected patients in Botswana after failure of thymidine analogue-based regimens. Journal of the International AIDS Society 20090101
Oxidative imbalance in HIV-1 infected patients treated with antiretroviral therapy. Journal of biomedicine & biotechnology 20090101
RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy. Retrovirology 20090101
RT-SHIV, an infectious CCR5-tropic chimeric virus suitable for evaluating HIV reverse transcriptase inhibitors in macaque models. AIDS research and therapy 20090101
The cost effectiveness of home-based provision of antiretroviral therapy in rural Uganda. Applied health economics and health policy 20090101
Viral load decay in antiretroviral-naïve patients receiving once-daily tenofovir and emtricitabine plus twice-daily nevirapine. HIV clinical trials 20090101
The prognosis of late presenters in the era of highly active antiretroviral therapy in serbia. The open virology journal 20090101
Progress in basic and clinical research on HIV resistance: report on the XVIII International HIV Drug Resistance Workshop. Antiviral therapy 20090101
Treatment of HIV infection: Swedish recommendations 2009. Scandinavian journal of infectious diseases 20090101
Factors influencing global antiretroviral procurement prices. BMC public health 20090101
Safety and tolerability of artemether-lumefantrine versus dihydroartemisinin-piperaquine for malaria in young HIV-infected and uninfected children. Malaria journal 20090101
German-Austrian recommendations for HIV1-therapy in pregnancy and in HIV1-exposed newborn, update 2008. European journal of medical research 20090101
Raltegravir in treatment naive patients. European journal of medical research 20090101
The association between alcohol use, alcohol use disorders and tuberculosis (TB). A systematic review. BMC public health 20090101
Combination antiretroviral drugs in PLGA nanoparticle for HIV-1. BMC infectious diseases 20090101
Early severe morbidity and resource utilization in South African adults on antiretroviral therapy. BMC infectious diseases 20090101
HIV reverse transcriptase: structural interpretation of drug resistant genetic variants from India. Bioinformation 20090101
Impact of previous virological treatment failures and adherence on the outcome of antiretroviral therapy in 2007. PloS one 20090101
Long term outcomes of antiretroviral therapy in a large HIV/AIDS care clinic in urban South Africa: a prospective cohort study. Journal of the International AIDS Society 20090101
Treatment outcomes and plasma level of ritonavir-boosted lopinavir monotherapy among HIV-infected patients who had NRTI and NNRTI failure. AIDS research and therapy 20090101
Effectiveness and safety of antiretrovirals with rifampicin: crucial issues for high-burden countries. Antiviral therapy 20090101
Adipocyte differentiation, mitochondrial gene expression and fat distribution: differences between zidovudine and tenofovir after 6 months. Antiviral therapy 20090101
Correlations between atazanavir C(trough )and hyperbilirubinemia: a case report. Journal of medical case reports 20090101
Long-term impact of efavirenz on neuropsychological performance and symptoms in HIV-infected individuals (ACTG 5097s). HIV clinical trials 20090101
Virologic suppression, treatment adherence, and improved quality of life on a once-daily efavirenz-based regimen in treatment-Naïve HIV-1-infected patients over 96 weeks. HIV clinical trials 20090101
Resistance and virological response analyses in a three initial treatment strategy trial: a substudy of the INITIO trial. HIV clinical trials 20090101
Long-term efficacy and safety of once-daily nevirapine in combination with tenofovir and emtricitabine in the treatment of HIV-infected patients: a 72-week prospective multicenter study (TENOR-trial). European journal of medical research 20090101
Genital tuberculosis as the cause of tuboovarian abscess in an immunosuppressed patient. Infectious diseases in obstetrics and gynecology 20090101
Raltegravir: The evidence of its therapeutic value in HIV-1 infection. Core evidence 20090101
Etravirine (TMC-125): The evidence for its place in the treatment of HIV-1 infection. Core evidence 20090101
Immune reconstitution inflammatory syndrome in AIDS-related non-hodgkin's lymphoma. Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology 20090101
Rapid and persistent selection of the K103N mutation as a majority quasispecies in a HIV1-patient exposed to efavirenz for three weeks: a case report and review of the literature. Journal of medical case reports 20090101
Severe myositis on commencement of efavirenz, abacavir and lamivudine, in the absence of lactic acidosis or classical abacavir hypersensitivity. BMJ case reports 20090101
CCR5 inhibitors: Emerging promising HIV therapeutic strategy. Indian journal of sexually transmitted diseases and AIDS 20090101
Clinico-epidemiological profile of HIV/TB coinfected patients in Vadodara, Gujarat. Indian journal of sexually transmitted diseases and AIDS 20090101
Role of darunavir in the management of HIV infection. HIV/AIDS (Auckland, N.Z.) 20090101
Pharmacologic and nonpharmacologic options for the management of HIV infection during pregnancy. HIV/AIDS (Auckland, N.Z.) 20090101
Neuropsychiatric sequelae in an efavirenz treated patient with hepatitis B. BMJ case reports 20090101
Limited-sampling strategies for anti-infective agents: systematic review. The Canadian journal of hospital pharmacy 20090101
Efavirenz induces CYP2B6-mediated hydroxylation of bupropion in healthy subjects. Journal of acquired immune deficiency syndromes (1999) 20081215
Design of annulated pyrazoles as inhibitors of HIV-1 reverse transcriptase. Journal of medicinal chemistry 20081211
Detection of low-frequency K103N mutants after unstructured discontinuation of efavirenz in the presence of the CYP2B6 516 TT polymorphism. The Journal of antimicrobial chemotherapy 20081201
Effects of the HIV treatment drugs nevirapine and efavirenz on brain creatine kinase activity. Metabolic brain disease 20081201
An HPLC-PDA method for the simultaneous quantification of the HIV integrase inhibitor raltegravir, the new nonnucleoside reverse transcriptase inhibitor etravirine, and 11 other antiretroviral agents in the plasma of HIV-infected patients. Therapeutic drug monitoring 20081201
Atazanavir: its role in HIV treatment. Expert review of anti-infective therapy 20081201
Gilead AIDS pill effective in study with weekends off. The AIDS reader 20081201
Renal impairment and hypersensitivity reaction due to efavirenz. Nephrology (Carlton, Vic.) 20081201
Switch to Viramune safe for some who can't tolerate Sustiva. Project Inform perspective 20081201
Study shows people can safely switch to Atripla. Project Inform perspective 20081201
Report from the 2008 joint ICAAC/IDSA meeting. Raltegravir vs. efavirenz in treatment-naive patients. AIDS clinical care 20081201
Report from the 2008 joint ICAAC/IDSA meeting. Maraviroc vs. efavirenz: a reanalysis of MERIT. AIDS clinical care 20081201
Increase of R-/S-methadone enantiomer concentration ratio in serum of patients treated with either nevirapine or efavirenz. Drug metabolism letters 20081201
Effect of African potato (Hypoxis hemerocallidea) on the pharmacokinetics of efavirenz. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20081201
[The 'induction-maintenance' strategy]. Enfermedades infecciosas y microbiologia clinica 20081201
[Clinical utility of atazanavir]. Enfermedades infecciosas y microbiologia clinica 20081201
Efavirenz-rifampicin interaction: therapeutic drug monitoring to efavirenz dosage optimization in HIV/TBC patients. AIDS (London, England) 20081130
Regression of HIV-related diffuse large B-cell lymphoma in response to antiviral therapy alone. Blood 20081115
Human immunodeficiency virus-induced uveitis: intraocular and plasma human immunodeficiency virus-1 RNA loads. Ophthalmology 20081101
Efficacy and tolerability of nevirapine- versus efavirenz-containing regimens in HIV-infected Thai children. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20081101
Impact of lipoatrophy on quality of life in HIV patients receiving anti-retroviral therapy. AIDS care 20081101
Changes in antioxidant profile among HIV-infected individuals on generic highly active antiretroviral therapy in southern India. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20081101
Prevalence of etravirine-associated mutations in clinical samples with resistance to nevirapine and efavirenz. The Journal of antimicrobial chemotherapy 20081101
Switch from zidovudine- to non-zidovudine-containing regimens is associated with modest haematological improvement and no obvious clinical benefit: a substudy of the ANRS 099 ALIZE trial. The Journal of antimicrobial chemotherapy 20081101
Modeling, prediction, and in vitro in vivo correlation of CYP3A4 induction. Drug metabolism and disposition: the biological fate of chemicals 20081101
Sensitive analysis of anti-HIV drugs, efavirenz, lopinavir and ritonavir, in human hair by liquid chromatography coupled with tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20081101
Towards novel S-DABOC inhibitors: synthesis, biological investigation, and molecular modeling studies. Bioorganic & medicinal chemistry letters 20081101
Slow efavirenz metabolism genotype is common in Botswana. Journal of acquired immune deficiency syndromes (1999) 20081101
HIV pharmacogenetics in clinical practice: recent achievements and future challenges. Current HIV research 20081101
Does short-term virologic failure translate to clinical events in antiretroviral-naïve patients initiating antiretroviral therapy in clinical practice? AIDS (London, England) 20081101
Short communication: Different mutation patterns in subtype CRF06_cpx after mother-to-child transmission. AIDS research and human retroviruses 20081101
Raltegravir phase III study data released. AIDS patient care and STDs 20081101
[Potential of integrase inhibitors to deplete HIV reservoirs or prevent their replenishment]. Enfermedades infecciosas y microbiologia clinica 20081101
[Pharmacokinetics and interactions of raltegravir]. Enfermedades infecciosas y microbiologia clinica 20081101
[Secondary effects associated with raltegravir]. Enfermedades infecciosas y microbiologia clinica 20081101
[Role of the new molecules in antiretroviral therapy. Position of raltegravir]. Enfermedades infecciosas y microbiologia clinica 20081101
Low trough levels of tipranavir in a combination antiretroviral therapy of tipranavir/ritonavir and tenofovir require therapeutic drug monitoring. European journal of medical research 20081027
Discovery of 3-{5-[(6-amino-1H-pyrazolo[3,4-b]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5-chlorobenzonitrile (MK-4965): a potent, orally bioavailable HIV-1 non-nucleoside reverse transcriptase inhibitor with improved potency against key mutant viruses. Journal of medicinal chemistry 20081023
Bayesian network analyses of resistance pathways against efavirenz and nevirapine. AIDS (London, England) 20081018
Efavirenz versus nevirapine-based initial treatment of HIV infection: clinical and virological outcomes in Southern African adults. AIDS (London, England) 20081018
The 3-year renal safety of a tenofovir disoproxil fumarate vs. a thymidine analogue-containing regimen in antiretroviral-naive patients. AIDS (London, England) 20081018
Didanosine, lamivudine, and efavirenz versus zidovudine, lamivudine, and efavirenz for the initial treatment of HIV type 1 infection: final analysis (48 weeks) of a prospective, randomized, noninferiority clinical trial, GESIDA 3903. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20081015
Phase II study of vicriviroc versus efavirenz (both with zidovudine/lamivudine) in treatment-naive subjects with HIV-1 infection. The Journal of infectious diseases 20081015
1,2,3-Thiadiazole thioacetanilides as a novel class of potent HIV-1 non-nucleoside reverse transcriptase inhibitors. Bioorganic & medicinal chemistry letters 20081015
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry 20081009
Pharmacokinetic interactions between depot medroxyprogesterone acetate and combination antiretroviral therapy. Fertility and sterility 20081001
Trends in the prescription of antiretroviral drugs and impact on plasma HIV-RNA measurements. The Journal of antimicrobial chemotherapy 20081001
Investigation of the mechanisms underlying the differential effects of the K262R mutation of P450 2B6 on catalytic activity. Molecular pharmacology 20081001
MAPPIT (MAmmalian Protein-Protein Interaction Trap) as a tool to study HIV reverse transcriptase dimerization in intact human cells. Journal of virological methods 20081001
Efavirenz concentrations in HIV-infected patients with and without viral hepatitis. British journal of clinical pharmacology 20081001
A randomized trial of combination hepatitis B therapy in HIV/HBV coinfected antiretroviral naïve individuals in Thailand. Hepatology (Baltimore, Md.) 20081001
Liver enzymes improve over twenty-four months of first-line non-nucleoside reverse transcriptase inhibitor-based therapy in rural Uganda. AIDS patient care and STDs 20081001
The pharmacokinetics and pharmacogenomics of efavirenz and lopinavir/ritonavir in HIV-infected persons requiring hemodialysis. AIDS (London, England) 20081001
The cost-effectiveness of HLA-B*5701 genetic screening to guide initial antiretroviral therapy for HIV. AIDS (London, England) 20081001
Cystoprostatectomy with ileal neobladder for treatment of severe cystitis glandularis in an AIDS patient. Clinics (Sao Paulo, Brazil) 20081001
[Two novel fixed formulations of nucleoside analogues (tenofovir-emtricitabine, and abacavir-lamivudine). Prospective, open study on clinical practice and therapeutic perspectives, in patients naïve and in subjects pre-treated with antiretrovirals]. Recenti progressi in medicina 20081001
[Maraviroc efficacy in clinical studies on the development of the molecule]. Enfermedades infecciosas y microbiologia clinica 20081001
Lopinavir/ritonavir in the treatment of HIV-1 infection: a review. Therapeutics and clinical risk management 20081001
Miscellaneous. Indian journal of pharmacology 20081001
Therapeutic monitoring is necessary for the association itraconazole and efavirenz in a patient with AIDS and disseminated histoplasmosis. AIDS (London, England) 20080912
Clinical impact of patient population differences and genomic variation in efavirenz therapy. AIDS (London, England) 20080912
Validation of the Accutrend lactate meter for hyperlactatemia screening during antiretroviral therapy in a resource-poor setting. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20080901
A survey of the syntheses of active pharmaceutical ingredients for antiretroviral drug combinations critical to access in emerging nations. Antiviral research 20080901
Effect of treatment with efavirenz on neuropsychiatric adverse events of interferon in HIV/HCV-coinfected patients. Journal of acquired immune deficiency syndromes (1999) 20080901
Pharmacokinetics of efavirenz when co-administered with rifampin in TB/HIV co-infected patients: pharmacogenetic effect of CYP2B6 variation. Journal of clinical pharmacology 20080901
CYP2B6: new insights into a historically overlooked cytochrome P450 isozyme. Current drug metabolism 20080901
Correlation between HIV-1 RNA load in blood and seminal plasma depending on antiretroviral treatment status, regimen and penetration of semen by antiretroviral drugs. Current HIV research 20080901
HIV infection in the elderly. Clinical interventions in aging 20080901
Structural basis for the improved drug resistance profile of new generation benzophenone non-nucleoside HIV-1 reverse transcriptase inhibitors. Journal of medicinal chemistry 20080828
Initial treatment of HIV-1 infection. The New England journal of medicine 20080828
Initial treatment of HIV-1 infection. The New England journal of medicine 20080828
Influence of antiretroviral drugs on the pharmacokinetics of prednisolone in HIV-infected individuals. Journal of acquired immune deficiency syndromes (1999) 20080815
5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile. Journal of medicinal chemistry 20080814
Endothelial function in human immunodeficiency virus-infected antiretroviral-naive subjects before and after starting potent antiretroviral therapy: The ACTG (AIDS Clinical Trials Group) Study 5152s. Journal of the American College of Cardiology 20080812
Outcomes of nevirapine- and efavirenz-based antiretroviral therapy when coadministered with rifampicin-based antitubercular therapy. JAMA 20080806
Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society-USA panel. JAMA 20080806
CYP3A induction and inhibition by different antiretroviral regimens reflected by changes in plasma 4beta-hydroxycholesterol levels. European journal of clinical pharmacology 20080801
The role of efavirenz compared with protease inhibitors in the body fat changes associated with highly active antiretroviral therapy. The Journal of antimicrobial chemotherapy 20080801
Pharmacokinetic interaction between efavirenz and carbamazepine after multiple-dose administration in healthy subjects. Journal of clinical pharmacology 20080801
Preclinical evaluation of 1H-benzylindole derivatives as novel human immunodeficiency virus integrase strand transfer inhibitors. Antimicrobial agents and chemotherapy 20080801
Efavirenz replacement by immediate full-dose nevirapine is safe in HIV-1-infected patients in Cambodia. HIV medicine 20080801
Novel N1-substituted 1,3-dihydro-2H-benzimidazol-2-ones as potent non-nucleoside reverse transcriptase inhibitors. Bioorganic & medicinal chemistry 20080801
Urogenital tuberculosis in a patient with AIDS: an unusual presentation. Nature clinical practice. Urology 20080801
Prevalence of possible drug-drug interactions between antiretroviral agents in different age groups in a section of the private health care sector setting in South Africa. Journal of clinical pharmacy and therapeutics 20080801
Efavirenz in human breast milk, mothers', and newborns' plasma. Journal of acquired immune deficiency syndromes (1999) 20080801
Lymphocyte mitochondrial depolarization and apoptosis in HIV-1-infected HAART patients. Journal of acquired immune deficiency syndromes (1999) 20080801
Anti-platelet-activating factor effects of highly active antiretroviral therapy (HAART): a new insight in the drug therapy of HIV infection? AIDS research and human retroviruses 20080801
Discovery and optimization of pyridazinone non-nucleoside inhibitors of HIV-1 reverse transcriptase. Bioorganic & medicinal chemistry letters 20080801
Determination of unbound antiretroviral drug concentrations by a modified ultrafiltration method reveals high variability in the free fraction. Therapeutic drug monitoring 20080801
Two cases of multidrug-resistant human immunodeficiency virus infection treated with atazanavir and lopinavir/ritonavir combination therapy. Journal of Korean medical science 20080801
The Relationship Between HIV Infection and Cardiovascular Disease. Current cardiology reviews 20080801
Hepatotoxicity in patients prescribed efavirenz or nevirapine. European journal of medical research 20080728
A 96-week comparison of lopinavir-ritonavir combination therapy followed by lopinavir-ritonavir monotherapy versus efavirenz combination therapy. The Journal of infectious diseases 20080715
Selective targeting of the HIV-1 reverse transcriptase catalytic complex through interaction with the 'primer grip' region by pyrrolobenzoxazepinone non-nucleoside inhibitors correlates with increased activity towards drug-resistant mutants. Biochemical pharmacology 20080715
Targeting of efavirenz loaded tuftsin conjugated poly(propyleneimine) dendrimers to HIV infected macrophages in vitro. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20080703
Pharmacokinetics and tolerability of artesunate and amodiaquine alone and in combination in healthy volunteers. European journal of clinical pharmacology 20080701
Pharmacy-refill measure of adherence to efavirenz can predict maintenance of HIV viral suppression. AIDS care 20080701
Safety and efficacy of simvastatin for the treatment of dyslipidemia in human immunodeficiency virus-infected patients receiving efavirenz-based highly active antiretroviral therapy. Pharmacotherapy 20080701
A multimodal, evidence-based approach to achieve lipid targets in the treatment of antiretroviral-associated dyslipidemia: case report and review of the literature. Pharmacotherapy 20080701
Improving non-nucleoside reverse transcriptase inhibitors for first-line treatment of HIV infection: the development pipeline and recent clinical data. Current opinion in drug discovery & development 20080701
Public-health and individual approaches to antiretroviral therapy: township South Africa and Switzerland compared. PLoS medicine 20080701
Efavirenz--still first-line king? Expert opinion on drug metabolism & toxicology 20080701
Outlook on Thailand's genomics and computational biology research and development. PLoS computational biology 20080701
Status epilepticus resulting from severe efavirenz toxicity in an HIV-infected patient. The AIDS reader 20080701
Minority HIV-1 drug resistance mutations are present in antiretroviral treatment-naïve populations and associate with reduced treatment efficacy. PLoS medicine 20080701
Transmitted minority drug-resistant HIV variants: a new epidemic? PLoS medicine 20080701
Concomitant use of nonnucleoside analogue reverse transcriptase inhibitors and rifampicin in TB/HIV type 1-coinfected patients. AIDS research and human retroviruses 20080701
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Antiretroviral rounds. Is that 'one pill' treatment enough? AIDS clinical care 20080701
Severe psoriasis due to cessation of antiretroviral therapy in a patient with human immunodeficiency virus. The Israel Medical Association journal : IMAJ 20080701
Clinical manifestations and antiretroviral management of HIV/AIDS patients with tuberculosis co-infection in Kramat 128 Hospital. Acta medica Indonesiana 20080701
Reverse transcriptase inhibitors induce cell differentiation and enhance the immunogenic phenotype in human renal clear-cell carcinoma. International journal of cancer 20080615
Parallel one-pot synthesis and structure-activity relationship study of symmetric formimidoester disulfides as a novel class of potent non-nucleoside HIV-1 reverse transcriptase inhibitors. Bioorganic & medicinal chemistry 20080615
Effect of semen sampling frequency on seminal antiretroviral drug concentration. Clinical pharmacology and therapeutics 20080601
Structural basis for drug resistance mechanisms for non-nucleoside inhibitors of HIV reverse transcriptase. Virus research 20080601
Comparison of immortalized Fa2N-4 cells and human hepatocytes as in vitro models for cytochrome P450 induction. Drug metabolism and disposition: the biological fate of chemicals 20080601
Identification and characterization of potent CYP2B6 inhibitors in Woohwangcheongsimwon suspension, an herbal preparation used in the treatment and prevention of apoplexy in Korea and China. Drug metabolism and disposition: the biological fate of chemicals 20080601
Antiviral efficacy, tolerability and pharmacokinetics of efavirenz in an unselected cohort of HIV-infected children. The Journal of antimicrobial chemotherapy 20080601
First-line antiretroviral therapy with efavirenz or lopinavir/ritonavir plus two nucleoside analogues: the SUSKA study, a non-randomized comparison from the VACH cohort. The Journal of antimicrobial chemotherapy 20080601
Mechanisms of inhibition of HIV replication by non-nucleoside reverse transcriptase inhibitors. Virus research 20080601
Effects of HIV antiretrovirals on the pharmacokinetics of hormonal contraceptives. The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception 20080601
Successful use of reduced-dose efavirenz in a patient with human immunodeficiency virus infection: case report and review of the literature. Pharmacotherapy 20080601
Long-term efficacy and tolerance of efavirenz- and nevirapine-containing regimens in adult HIV type 1 Senegalese patients. AIDS research and human retroviruses 20080601
Short communication: oral lesions in HIV/AIDS patients undergoing HAART including efavirenz. AIDS research and human retroviruses 20080601
Pharmacogenomics of antiretrovirals. Recent patents on anti-infective drug discovery 20080601
Atriplatrade mark - HIV therapy in one pill. Therapeutics and clinical risk management 20080601
The cost-effectiveness analysis of initiating HIV/AIDS treatment with efavirenz-based regimens compared with nevirapine-based regimens in Thailand. Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20080601
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Stability of antiretroviral regimens in patients with viral suppression. AIDS (London, England) 20080531
Plasma drug concentrations and virologic evaluations after stopping treatment with nonnucleoside reverse-transcriptase inhibitors in HIV type 1-infected children. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080515
Quantification of protease inhibitors and non-nucleoside reverse transcriptase inhibitors in dried blood spots by liquid chromatography-triple quadrupole mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080515
Class-sparing regimens for initial treatment of HIV-1 infection. The New England journal of medicine 20080515
Initial treatment for HIV infection--an embarrassment of riches. The New England journal of medicine 20080515
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Haematological changes after switching from stavudine to zidovudine in HIV-infected children receiving highly active antiretroviral therapy. HIV medicine 20080501
A study of the binding energies of efavirenz to wild-type and K103N/Y181C HIV-1 reverse transcriptase based on the ONIOM method. ChemMedChem 20080501
[Efavirenz versus indinavir among HIV-1 naive patients in Abidjan (Ivory Coast)]. Medecine et maladies infectieuses 20080501
Standard-dose efavirenz vs. standard-dose nevirapine in antiretroviral regimens among HIV-1 and tuberculosis co-infected patients who received rifampicin. HIV medicine 20080501
Complexity of interactions between voriconazole and antiretroviral agents. The Annals of pharmacotherapy 20080501
Viral population estimation using pyrosequencing. PLoS computational biology 20080501
Undetectable HIV-1 viral load in the fluid of bullous skin lesion in a patient receiving highly active antiretroviral therapy. International journal of STD & AIDS 20080501
Pharmacy refill adherence compared with CD4 count changes for monitoring HIV-infected adults on antiretroviral therapy. PLoS medicine 20080501
Antiretroviral therapy in developing countries: pharmacologic considerations. Current opinion in HIV and AIDS 20080501
Switch to efavirenz (EFV) after protease-inhibitor (PI)-failure: explorative analysis of outcome by baseline viral VS tolerability failure. European journal of medical research 20080430
[Complete HAART in a single pill. New milestone for improving compliance]. MMW Fortschritte der Medizin 20080428
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[One pill--all HAART. Complete divergent HAART in a single tablet per day]. MMW Fortschritte der Medizin 20080428
Factors associated with the emergence of K65R in patients with HIV-1 infection treated with combination antiretroviral therapy containing tenofovir. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080415
High prevalence of the CYP2B6 516G-->T(*6) variant and effect on the population pharmacokinetics of efavirenz in HIV/AIDS outpatients in Zimbabwe. European journal of clinical pharmacology 20080401
Aberrant splicing caused by single nucleotide polymorphism c.516G>T [Q172H], a marker of CYP2B6*6, is responsible for decreased expression and activity of CYP2B6 in liver. The Journal of pharmacology and experimental therapeutics 20080401
Anti-HIV activity and resistance profile of the CXC chemokine receptor 4 antagonist POL3026. Molecular pharmacology 20080401
Optimizing efavirenz treatment: CYP2B6 genotyping or therapeutic drug monitoring? European journal of clinical pharmacology 20080401
Thiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 1: Parallel synthesis, molecular modelling and structure-activity relationship studies on O-[2-(hetero)arylethyl]-N-phenylthiocarbamates. Bioorganic & medicinal chemistry 20080401
Thiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 2: Parallel synthesis, molecular modelling and structure-activity relationship studies on analogues of O-(2-phenylethyl)-N-phenylthiocarbamate. Bioorganic & medicinal chemistry 20080401
Synthesis and biological evaluation of novel 6-substituted 5-alkyl-2-(arylcarbonylmethylthio)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors. Bioorganic & medicinal chemistry 20080401
Impact of CYP2B6 983T>C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients. The Journal of antimicrobial chemotherapy 20080401
Recent availability of two novel, fixed formulations of antiretroviral nucleoside analogues: a 12-month prospective, open-label survey of their practical use and therapeutic perspectives in antiretroviral-naive and -experienced patients. AIDS patient care and STDs 20080401
Pharmacokinetic interactions of efavirenz and voriconazole in healthy volunteers. British journal of clinical pharmacology 20080401
Are literature references sufficient for dose recommendations? An FDA case study of efavirenz and rifampin. Journal of clinical pharmacology 20080401
Effects of CYP3A4 inducers with and without CYP3A4 inhibitors on the pharmacokinetics of maraviroc in healthy volunteers. British journal of clinical pharmacology 20080401
A novel probe drug interaction study to investigate the effect of selected antiretroviral combinations on the pharmacokinetics of a single oral dose of maraviroc in HIV-positive subjects. British journal of clinical pharmacology 20080401
Efavirenz-based regimens in treatment-naive patients with a range of pretreatment HIV-1 RNA levels and CD4 cell counts. The Journal of infectious diseases 20080401
Spectrum of adverse events after generic HAART in southern Indian HIV-infected patients. AIDS patient care and STDs 20080401
[Evaluation of antiretroviral therapy in HIV-infected adults in the Department of Haematology, University Hospital of Brazzavllle, Congo]. Bulletin de la Societe de pathologie exotique (1990) 20080401
The debate about marijuana usage in transplant candidates: recent medical evidence on marijuana health effects. Current opinion in organ transplantation 20080401
New approaches in the treatment of HIV/AIDS - focus on maraviroc and other CCR5 antagonists. Therapeutics and clinical risk management 20080401
Raltegravir: first in class HIV integrase inhibitor. Therapeutics and clinical risk management 20080401
'One pill, once daily': what clinicians need to know about Atriplatrade mark. Therapeutics and clinical risk management 20080401
FDA notifications. Generic stavudine and efavirenz are tentatively approved by FDA. AIDS alert 20080401
Association of antiretroviral therapy with fibrinogen levels in HIV-infection. AIDS (London, England) 20080330
Preexisting resistance to nonnucleoside reverse-transcriptase inhibitors predicts virologic failure of an efavirenz-based regimen in treatment-naive HIV-1-infected subjects. The Journal of infectious diseases 20080315
Hemochromatosis gene polymorphisms, mitochondrial haplogroups, and peripheral lipoatrophy during antiretroviral therapy. The Journal of infectious diseases 20080315
Monitoring the development of non-nucleoside reverse transcriptase inhibitor-associated resistant HIV-1 using an electrochemiluminescence-based reverse transcriptase polymerase assay. Analytical biochemistry 20080301
Pharmacokinetic interaction between efavirenz and dual protease inhibitors in healthy volunteers. Biopharmaceutics & drug disposition 20080301
A human immunodeficiency virus protease inhibitor is a novel functional inhibitor of human pregnane X receptor. Drug metabolism and disposition: the biological fate of chemicals 20080301
Lipodystrophy and weight changes: data from the Swiss HIV Cohort Study, 2000-2006. HIV medicine 20080301
Antiretroviral drug concentrations and HIV RNA in the genital tract of HIV-infected women receiving long-term highly active antiretroviral therapy. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080301
Efavirenz-induced hypersensitivity reaction manifesting in rash and hepatitis in a Latino male. The Annals of pharmacotherapy 20080301
Determination of abacavir, amprenavir, didanosine, efavirenz, nevirapine, and stavudine concentration in human plasma by MALDI-TOF/TOF. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080301
Prevalence and epidemiology of HIV type 1 drug resistance among newly diagnosed therapy-naive patients in Belgium from 2003 to 2006. AIDS research and human retroviruses 20080301
Impact of residues in the nonnucleoside reverse transcriptase inhibitor binding pocket on HIV-1 reverse transcriptase heterodimer stability. Current HIV research 20080301
Changes in lipid profile over 24 months among adults on first-line highly active antiretroviral therapy in the home-based AIDS care program in rural Uganda. Journal of acquired immune deficiency syndromes (1999) 20080301
A case of human bite by an 11-year old HIV positive girl in a paediatrics ward. African journal of medicine and medical sciences 20080301
Ischemic maculopathy in zidovudine-induced anemia in an HIV-positive man. Clinical ophthalmology (Auckland, N.Z.) 20080301
HLA-DRB1*01 associated with cutaneous hypersensitivity induced by nevirapine and efavirenz. AIDS (London, England) 20080219
Maternal 12-month response to antiretroviral therapy following prevention of mother-to-child transmission of HIV type 1, Ivory Coast, 2003-2006. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080215
Pharmacokinetics and pharmacodynamics of efavirenz and nelfinavir in HIV-infected children participating in an area-under-the-curve controlled trial. Clinical pharmacology and therapeutics 20080201
Efavirenz accelerates HIV-1 reverse transcriptase ribonuclease H cleavage, leading to diminished zidovudine excision. Molecular pharmacology 20080201
Triazole derivatives as non-nucleoside inhibitors of HIV-1 reverse transcriptase--structure-activity relationships and crystallographic analysis. Bioorganic & medicinal chemistry letters 20080201
3D-QSAR models on clinically relevant K103N mutant HIV-1 reverse transcriptase obtained from two strategic considerations. Bioorganic & medicinal chemistry letters 20080201
Energetic effects for observed and unobserved HIV-1 reverse transcriptase mutations of residues L100, V106, and Y181 in the presence of nevirapine and efavirenz. Bioorganic & medicinal chemistry letters 20080201
Intra-individual variability in efavirenz plasma concentrations supports therapeutic drug monitoring based on quarterly sampling in the first year of therapy. Therapeutic drug monitoring 20080201
Safety and tolerability of depot medroxyprogesterone acetate among HIV-infected women on antiretroviral therapy: ACTG A5093. Contraception 20080201
Impact of nevirapine or efavirenz co-administration on ritonavir-boosted amprenavir pharmacokinetics in HIV-infected patients. Fundamental & clinical pharmacology 20080201
A ten-year analysis of the incidence and risk factors for acute pancreatitis requiring hospitalization in an urban HIV clinical cohort. AIDS patient care and STDs 20080201
Cost-effectiveness analysis of emtricitabine/tenofovir versus lamivudine/zidovudine, in combination with efavirenz, in antiretroviral-naive, HIV-1-infected patients. Clinical therapeutics 20080201
Hemorrhagic cardiomyopathy in male mice treated with an NNRTI: the role of vitamin K. Toxicologic pathology 20080201
Validated enantiospecific LC method for determination of (R)-enantiomer impurity in (S)-efavirenz. Die Pharmazie 20080201
[Polyneuropathies in patients treated with HAART in Bobo-Dioulasso hospital, Burkina Faso]. Bulletin de la Societe de pathologie exotique (1990) 20080201
FDA notifications. FDA grants tentative approval of generic efavirenz tablets. AIDS alert 20080201
Comparison of genotypic resistance profiles and virological response between patients starting nevirapine and efavirenz in EuroSIDA. AIDS (London, England) 20080130
Induction therapy with trizivir plus efavirenz or lopinavir/ritonavir followed by trizivir alone in naive HIV-1-infected adults. AIDS (London, England) 20080130
Efficacy and tolerability of long-term efavirenz plus nucleoside reverse transcriptase inhibitors for HIV-1 infection. AIDS (London, England) 20080111
Mechanism of inhibition of HIV-1 reverse transcriptase by the novel broad-range DNA polymerase inhibitor N-{2-[4-(aminosulfonyl)phenyl]ethyl}-2-(2-thienyl)acetamide. Biochemistry 20080108
Antiretroviral therapy using zidovudine, lamivudine, and efavirenz in South Africa: tolerability and clinical events. AIDS (London, England) 20080102
Clinical interaction between efavirenz and phenytoin. AIDS (London, England) 20080102
Synthesis and antiviral activity of new dimeric inhibitors against HIV-1. Bioorganic & medicinal chemistry 20080101
Comparative evaluation of the inhibitory activities of a series of pyrimidinedione congeners that inhibit human immunodeficiency virus types 1 and 2. Antimicrobial agents and chemotherapy 20080101
Tenofovir disoproxil fumarate, emtricitabine, and efavirenz compared with zidovudine/lamivudine and efavirenz in treatment-naive patients: 144-week analysis. Journal of acquired immune deficiency syndromes (1999) 20080101
Pharmacokinetic interaction between voriconazole and efavirenz at steady state in healthy male subjects. Journal of clinical pharmacology 20080101
Synthesis and antiviral evaluation of 6-(trifluoromethylbenzyl) and 6-(fluorobenzyl) analogues of HIV drugs emivirine and GCA-186. Archiv der Pharmazie 20080101
Association between exposure to nevirapine and reduced liver fibrosis progression in patients with HIV and hepatitis C virus coinfection. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080101
Drug interactions between warfarin and efavirenz or lopinavir-ritonavir in clinical treatment. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080101
Low-level HIV-1 replication and the dynamics of the resting CD4+ T cell reservoir for HIV-1 in the setting of HAART. BMC infectious diseases 20080101
Oral adverse effects due to the use of Nevirapine. The journal of contemporary dental practice 20080101
Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice. PLoS medicine 20080101
Patterns and predictors of the use of different antiretroviral drug regimens at treatment initiation in the UK. HIV medicine 20080101
Association of efavirenz hypersusceptibility with virologic response in ACTG 368, a randomized trial of abacavir (ABC) in combination with efavirenz (EFV) and indinavir (IDV) in HIV-infected subjects with prior nucleoside analog experience. HIV clinical trials 20080101
Going beyond efficacy: strategies for cancer pain management. Current oncology (Toronto, Ont.) 20080101
Summary of presentations at the NIH/NIAID New Humanized Rodent Models 2007 Workshop. AIDS research and therapy 20080101
The incidence of multidrug and full class resistance in HIV-1 infected patients is decreasing over time (2001-2006) in Portugal. Retrovirology 20080101
Implementation and effectiveness of antiretroviral therapy in Greenland. Emerging infectious diseases 20080101
Long-term assessment of didanosine, lamivudine, and efavirenz in antiretroviral-naive patients: 3-year follow-up. AIDS research and human retroviruses 20080101
The cost of antiretroviral therapy in Haiti. Cost effectiveness and resource allocation : C/E 20080101
Plasma HIV load and proviral DNA decreases after two standard antiretroviral regimens in HIV-positive patients naïve to antiretrovirals. Current HIV research 20080101
Twenty-four-week safety and tolerability of nevirapine vs. abacavir in combination with zidovudine/lamivudine as first-line antiretroviral therapy: a randomized double-blind trial (NORA). Tropical medicine & international health : TM & IH 20080101
Adaptation of antiretroviral therapy in human immunodeficiency virus infection with central nervous system involvement. Journal of neurovirology 20080101
Overestimates of survival after HAART: implications for global scale-up efforts. PloS one 20080101
Anti-tuberculosis therapy-induced hepatotoxicity among Ethiopian HIV-positive and negative patients. PloS one 20080101
Aqueous extracts from peppermint, sage and lemon balm leaves display potent anti-HIV-1 activity by increasing the virion density. Retrovirology 20080101
Efficacy and safety of once-daily regimens in the treatment of HIV infection. Drugs 20080101
Extracellular ATP reduces HIV-1 transfer from immature dendritic cells to CD4+ T lymphocytes. Retrovirology 20080101
Fosamprenavir or atazanavir once daily boosted with ritonavir 100 mg, plus tenofovir/emtricitabine, for the initial treatment of HIV infection: 48-week results of ALERT. AIDS research and therapy 20080101
Acute renal failure in an AIDS patient on tenofovir: a case report. Journal of medical case reports 20080101
Characterization of drug resistance in antiretroviral-treated patients infected with HIV-1 CRF02_AG and AGK subtypes in Mali and Burkina Faso. Antiviral therapy 20080101
Predictors of mortality in HIV-infected patients starting antiretroviral therapy in a rural hospital in Tanzania. BMC infectious diseases 20080101
Metabolic and immune activation effects of treatment interruption in chronic HIV-1 infection: implications for cardiovascular risk. PloS one 20080101
Streamlining tasks and roles to expand treatment and care for HIV: randomised controlled trial protocol. Trials 20080101
Imbalanced effector and regulatory cytokine responses may underlie mycobacterial immune restoration disease. AIDS research and therapy 20080101
European Commission approves Atripla. AIDS patient care and STDs 20080101
Impact of switching virologically suppressed, HIV-1-infected patients from twice-daily fixed-dose zidovudine/lamivudine to once-daily fixed-dose tenofovir disoproxil fumarate/emtricitabine. HIV clinical trials 20080101
Antiviral activity and safety of aplaviroc with lamivudine/zidovudine in HIV-infected, therapy-naive patients: the ASCENT (CCR102881) study. Antiviral therapy 20080101
Highly diversified multiply drug-resistant HIV-1 quasispecies in PBMCs: a case report. Retrovirology 20080101
Prevalence of dyslipidemia and dysglycaemia in HIV infected patients. East African medical journal 20080101
Randomization to once-daily stavudine extended release/lamivudine/efavirenz versus a more frequent regimen improves adherence while maintaining viral suppression. HIV clinical trials 20080101
How long is the window of opportunity between adherence failure and virologic failure on efavirenz-based HAART? HIV clinical trials 20080101
Adverse effects of antiretroviral treatment. Indian journal of dermatology, venereology and leprology 20080101
Mouse T-cells restrict replication of human immunodeficiency virus at the level of integration. Retrovirology 20080101
Viral complementation allows HIV-1 replication without integration. Retrovirology 20080101
Risk factors for poor virological outcome at 12 months in a workplace-based antiretroviral therapy programme in South Africa: a cohort study. BMC infectious diseases 20080101
Viral hepatitis and HIV-associated tuberculosis: risk factors and TB treatment outcomes in Thailand. BMC public health 20080101
Prevalence of drug resistance and associated mutations in HIV-positive Puerto Ricans: sex variations. Ethnicity & disease 20080101
CCR5Delta32 genotypes in a German HIV-1 seroconverter cohort and report of HIV-1 infection in a CCR5Delta32 homozygous individual. PloS one 20080101
Not all missed doses are the same: sustained NNRTI treatment interruptions predict HIV rebound at low-to-moderate adherence levels. PloS one 20080101
Prevalence and risk factors for etravirine resistance among patients failing on non-nucleoside reverse transcriptase inhibitors. Antiviral therapy 20080101
Hepatic steatosis in patients with HIV-Hepatitis C Virus coinfection: is it associated with antiretroviral therapy and more advanced hepatic fibrosis? BMC research notes 20080101
Correlation between CD4 counts of HIV patients and enteric protozoan in different seasons - an experience of a tertiary care hospital in Varanasi (India). BMC gastroenterology 20080101
Factors influencing efavirenz and nevirapine plasma concentration: effect of ethnicity, weight and co-medication. Antiviral therapy 20080101
Adherence to antiretroviral therapy in young children in Cape Town, South Africa, measured by medication return and caregiver self-report: a prospective cohort study. BMC pediatrics 20080101
In vitro evidence for a new therapeutic approach in renal cell carcinoma. International braz j urol : official journal of the Brazilian Society of Urology 20080101
General framework for the prediction of oral drug interactions caused by CYP3A4 induction from in vivo information. Clinical pharmacokinetics 20080101
Resting regulatory CD4 T cells: a site of HIV persistence in patients on long-term effective antiretroviral therapy. PloS one 20080101
Success with antiretroviral treatment for children in Kigali, Rwanda: experience with health center/nurse-based care. BMC pediatrics 20080101
A pharmacokinetic and pharmacogenetic study of efavirenz in children: dosing guidelines can result in subtherapeutic concentrations. Antiviral therapy 20080101
Durability of stavudine, lamivudine and nevirapine among advanced HIV-1 infected patients with/without prior co-administration of rifampicin: a 144-week prospective study. BMC infectious diseases 20080101
Impending flop for brand antiretrovirals in the emerging markets? The open AIDS journal 20080101
Dyslipidemia and cardiovascular disease risk factor management in HIV-1-infected subjects treated with HAART in the Spanish VACH cohort. The open AIDS journal 20080101
Effectiveness and safety of generic fixed-dose combination of tenofovir/emtricitabine/efavirenz in HIV-1-infected patients in Western India. Medscape journal of medicine 20080101
Single-measurement therapeutic drug monitoring of the HIV/AIDS drugs abacavir, zidovudine, lamivudine, efavirenz, nevirapine, lopinavir and nelfinavir. Pharmacology 20080101
Outcome of protease inhibitor substitution with nevirapine in HIV-1 infected children. BMC infectious diseases 20080101
A feasibility study of immediate versus deferred antiretroviral therapy in children with HIV infection. AIDS research and therapy 20080101
Successful treatment with azithromycin and rifampicin of penicillin and cephalosporin insensitive pneumococcal osteomyelitis in a child with HIV infection: a case report. Cases journal 20080101
Magnitude and complexity of rectal mucosa HIV-1-specific CD8+ T-cell responses during chronic infection reflect clinical status. PloS one 20080101
Virologic, immunologic, clinical, safety, and resistance outcomes from a long-term comparison of efavirenz-based versus nevirapine-based antiretroviral regimens as initial therapy in HIV-1-infected persons. HIV clinical trials 20080101
Prevention of the sexual transmission of HIV-1: preparing for success. Journal of the International AIDS Society 20080101
Biphasic decay kinetics suggest progressive slowing in turnover of latently HIV-1 infected cells during antiretroviral therapy. Retrovirology 20080101
Variability in the plasma concentration of efavirenz and nevirapine is associated with genotypic resistance after treatment interruption. Antiviral therapy 20080101
Human immunodeficiency virus seroconversion presenting with acute inflammatory demyelinating polyneuropathy: a case report. Journal of medical case reports 20080101
Adherence to highly active antiretroviral therapy and its correlates among HIV infected pediatric patients in Ethiopia. BMC pediatrics 20080101
Three generic nevirapine-based antiretroviral treatments in Chinese HIV/AIDS patients: multicentric observation cohort. PloS one 20080101
Small individual loans and mental health: a randomized controlled trial among South African adults. BMC public health 20080101
Topical application of entry inhibitors as 'virustats' to prevent sexual transmission of HIV infection. Retrovirology 20080101
Hepatitis A, B and C viral co-infections among HIV-infected adults presenting for care and treatment at Muhimbili National Hospital in Dar es Salaam, Tanzania. BMC public health 20080101
Depressive symptoms and exposure to efavirenz in West African HIV-infected adults. HIV clinical trials 20080101
High treatment success rates when switching to once daily nevirapine containing antiretroviral therapy. The open AIDS journal 20080101
Determinants of Treatment Access in a Population-based Cohort of HIV-positive Men and Women Living in Argentina. Journal of the International AIDS Society 20080101
Effectiveness and Safety of Generic Fixed-Dose Combination of Tenofovir/Emtricitabine/Efavirenz in HIV-1-Infected Patients in Western India. Journal of the International AIDS Society 20080101
Maraviroc in the treatment of HIV infection. Drug design, development and therapy 20080101
Raltegravir in the management of HIV-infected patients. Drug design, development and therapy 20080101
Determinants of retention in care in an antiretroviral therapy (ART) program in urban Cameroon, 2003-2005. The Pan African medical journal 20080101
Dihydro-alkylthio-benzyl-oxopyrimidines as inhibitors of reverse transcriptase: synthesis and rationalization of the biological data on both wild-type enzyme and relevant clinical mutants. Journal of medicinal chemistry 20071227
Racial differences in virologic failure associated with adherence and quality of life on efavirenz-containing regimens for initial HIV therapy: results of ACTG A5095. Journal of acquired immune deficiency syndromes (1999) 20071215
[HIV-1 genotypic resistance profiles in children failing highly active antiretroviral therapy]. Zhonghua yi xue za zhi 20071211
Pharmacogenetics of efavirenz: adherence and virologic outcomes. Annals of internal medicine 20071204
A randomized controlled trial of therapeutic drug monitoring in treatment-naive and -experienced HIV-1-infected patients. Journal of acquired immune deficiency syndromes (1999) 20071201
Adherence to HAART therapy measured by electronic monitoring in newly diagnosed HIV patients in Botswana. European journal of clinical pharmacology 20071201
Immunosuppressant pharmacokinetics and dosing modifications in HIV-1 infected liver and kidney transplant recipients. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20071201
Improved interpretation of genotypic changes in the HIV-1 reverse transcriptase coding region that determine the virological response to didanosine. The Journal of infectious diseases 20071201
N348I in the connection domain of HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance. PLoS medicine 20071201
Initiating highly active antiretroviral therapy with newer protease inhibitors is associated with better survival compared to first-generation protease inhibitors or nevirapine. AIDS patient care and STDs 20071201
Nitroimidazoles. V. Synthesis and anti-HIV evaluation of new 5-substituted piperazinyl-4-nitroimidazole derivatives. Acta pharmaceutica (Zagreb, Croatia) 20071201
Characterization of HIV-1 subtypes and viral antiretroviral drug resistance in men who have sex with men in Beijing, China. AIDS (London, England) 20071201
Review of tenofovir-emtricitabine. Therapeutics and clinical risk management 20071201
Metabolic syndrome, cardiovascular disease and type 2 diabetes mellitus after initiation of antiretroviral therapy in HIV infection. AIDS (London, England) 20071130
Vanadium induces VL30 retrotransposition at an unusually high level: a possible carcinogenesis mechanism. Journal of molecular biology 20071116
HPLC-MS method for the simultaneous quantification of the new HIV protease inhibitor darunavir, and 11 other antiretroviral agents in plasma of HIV-infected patients. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071115
Psychosis in a 12-year-old HIV-positive girl with an increased serum concentration of efavirenz. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20071115
Positive outcomes of HAART at 24 months in HIV-infected patients in Cambodia. AIDS (London, England) 20071112
Antiretroviral therapy with the integrase inhibitor raltegravir alters decay kinetics of HIV, significantly reducing the second phase. AIDS (London, England) 20071112
Investigation of human pharmacoscintigraphic behavior of two tablets and a capsule formulation of a high dose, poorly water soluble/highly permeable drug (efavirenz). Journal of pharmaceutical sciences 20071101
HIV/AIDS-specific quality of life and adherence to antiretroviral therapy over time. Journal of acquired immune deficiency syndromes (1999) 20071101
Synthesis and biological properties of novel 2-aminopyrimidin-4(3H)-ones highly potent against HIV-1 mutant strains. Journal of medicinal chemistry 20071101
Successful efavirenz dose reduction in HIV type 1-infected individuals with cytochrome P450 2B6 *6 and *26. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20071101
From docking false-positive to active anti-HIV agent. Journal of medicinal chemistry 20071101
Is it safe to switch between efavirenz and nevirapine in the event of toxicity? The Lancet. Infectious diseases 20071101
Evolution of antiretroviral drug costs in Brazil in the context of free and universal access to AIDS treatment. PLoS medicine 20071101
Liver enzymes elevation and immune reconstitution among treatment-naïve HIV-infected patients instituting antiretroviral therapy. The American journal of the medical sciences 20071101
Design, synthesis and pharmacological evaluation of HIV-1 reverse transcriptase inhibition of new indolin-2-ones. Medicinal chemistry (Shariqah (United Arab Emirates)) 20071101
Quantifying antiretroviral risk in pregnancy. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20071101
European CHMP issues positive opinion for Atripla. AIDS patient care and STDs 20071101
Outcomes in HIV-infected patients on antiretroviral therapy with tuberculosis. The Southeast Asian journal of tropical medicine and public health 20071101
Clinical outcomes and CD4 cell response in children receiving antiretroviral therapy at primary health care facilities in Zambia. JAMA 20071024
CYP2B6 genetic variants are associated with nevirapine pharmacokinetics and clinical response in HIV-1-infected children. AIDS (London, England) 20071018
CCR5 antagonists: comparison of efficacy, side effects, pharmacokinetics and interactions--review of the literature. European journal of medical research 20071015
CCR5 antagonists in the treatment of treatment-naive patients infected with CCR5 tropic HIV-1. European journal of medical research 20071015
Treatment with CCR5 antagonists: which patient may have a benefit? European journal of medical research 20071015
Indolyl aryl sulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors: role of two halogen atoms at the indole ring in developing new analogues with improved antiviral activity. Journal of medicinal chemistry 20071004
N2-benzyloxycarbonylguan-9-yl acetic acid derivatives as HIV-1 reverse transcriptase non-nucleoside inhibitors with decreased loss of potency against common drug-resistance mutations. ChemMedChem 20071001
Identification and characterization of UK-201844, a novel inhibitor that interferes with human immunodeficiency virus type 1 gp160 processing. Antimicrobial agents and chemotherapy 20071001
Bioequivalence of efavirenz/emtricitabine/tenofovir disoproxil fumarate single-tablet regimen. Journal of acquired immune deficiency syndromes (1999) 20071001
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Prednisolone mediated suppression of HIV-1 viral load strongly correlates with C-C chemokine CCL2: In vivo and in vitro findings. Clinical immunology (Orlando, Fla.) 20071001
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Treatment of an atazanivir associated grade 4 hyperbilirubinaemia with efavirenz. Gut 20071001
Partial deletion of CYP2B6 owing to unequal crossover with CYP2B7. Pharmacogenetics and genomics 20071001
Genotypic resistance in HIV-infected naive patients receiving abacavir plus lamivudine and efavirenz. Journal of acquired immune deficiency syndromes (1999) 20071001
Effect of anticoagulants on plasma nevirapine and efavirenz concentrations. Therapeutic drug monitoring 20071001
The validation of plasma darunavir concentrations determined by the HPLC method for protease inhibitors. Biological & pharmaceutical bulletin 20071001
Early contraceptive failure of Implanon in an HIV-seropositive patient on triple antiretroviral therapy with zidovudine, lamivudine and efavirenz. The journal of family planning and reproductive health care 20071001
Health-related quality of life outcomes in HIV-infected patients starting different combination regimens in a randomized multinational trial: the INITIO-QoL substudy. AIDS research and human retroviruses 20071001
Efficacy and safety of a once daily regimen with efavirenz, lamivudine, and didanosine, with and without food, as initial therapy for HIV Infection: the ELADI study. AIDS research and human retroviruses 20071001
Use of fMRI to predict psychiatric adverse effects of interferon treatment for Hepatitis C - preliminary report. Neuropsychiatric disease and treatment 20071001
Potent inhibition of HIV-1 replication by novel non-peptidyl small molecule inhibitors of protease dimerization. The Journal of biological chemistry 20070928
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Antiretroviral drug exposure in the female genital tract: implications for oral pre- and post-exposure prophylaxis. AIDS (London, England) 20070912
Efavirenz urolithiasis. AIDS (London, England) 20070912
A comparison of three initial antiretroviral AIDS regimens. The New England journal of medicine 20070906
CYP2B6 983T>C polymorphism is prevalent in West Africa but absent in Papua New Guinea: implications for HIV/AIDS treatment. British journal of clinical pharmacology 20070901
Response to efavirenz-containing regimens in previously antiretroviral-naive HIV-positive patients: the role of gender. Journal of acquired immune deficiency syndromes (1999) 20070901
Hepatotoxicity of antiretroviral drugs is reduced after successful treatment of chronic hepatitis C in HIV-infected patients. The Journal of infectious diseases 20070901
Optimal timing and best antiretroviral regimen in treatment-naive HIV-infected individuals with advanced disease. Journal of acquired immune deficiency syndromes (1999) 20070901
Patient preferences among third agent HIV medications: a US and German perspective. AIDS care 20070901
Maraviroc reduces viral load in naive patients at 48 weeks. AIDS patient care and STDs 20070901
FDA notifications. FDA grants tentative approval of efavirenz. AIDS alert 20070901
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Efavirenz-therapy in HIV-patients with underlying liver disease: importance of continuous TDM of EFV. European journal of medical research 20070816
Long-term body fat outcomes in antiretroviral-naive participants randomized to nelfinavir or efavirenz or both plus dual nucleosides. Dual X-ray absorptiometry results from A5005s, a substudy of Adult Clinical Trials Group 384. Journal of acquired immune deficiency syndromes (1999) 20070815
Safety of switching to nevirapine-based highly active antiretroviral therapy at elevated CD4 cell counts in a resource-constrained setting. Journal of acquired immune deficiency syndromes (1999) 20070815
Amodiaquine metabolism is impaired by common polymorphisms in CYP2C8: implications for malaria treatment in Africa. Clinical pharmacology and therapeutics 20070801
Long-term safety and efficacy of a once-daily regimen of emtricitabine, didanosine, and efavirenz in HIV-infected, therapy-naive children and adolescents: Pediatric AIDS Clinical Trials Group Protocol P1021. Pediatrics 20070801
Hair loss induced by lopinavir-ritonavir. Pharmacotherapy 20070801
Probing nonnucleoside inhibitor-induced active-site distortion in HIV-1 reverse transcriptase by transient kinetic analyses. Protein science : a publication of the Protein Society 20070801
Efavirenz-induced neurological symptoms in rare homozygote CYP2B6 *2/*2 (C64T). International journal of STD & AIDS 20070801
Data shows long-term nevirapine efficacy and increases in good cholesterol. AIDS patient care and STDs 20070801
Antiretroviral treatment and prevention of peripartum and postnatal HIV transmission in West Africa: evaluation of a two-tiered approach. PLoS medicine 20070801
No observable correlation between central nervous system side effects and EFV plasma concentrations in Japanese HIV type 1-infected patients treated with EFV containing HAART. AIDS research and human retroviruses 20070801
Baseline genotype as a predictor of virological failure to emtricitabine or stavudine in combination with didanosine and efavirenz. AIDS research and human retroviruses 20070801
Genotypic analysis of the protease and reverse transcriptase of HIV type 1 isolates from recently infected injecting drug users in western China. AIDS research and human retroviruses 20070801
Teratogenicity risk of antiretroviral therapy in pregnancy. Current HIV/AIDS reports 20070801
144-week data released on Gilead's study 934. AIDS patient care and STDs 20070801
The renaissance of fixed dose combinations: Combivir. Therapeutics and clinical risk management 20070801
Review of tipranavir in the treatment of drug-resistant HIV. Therapeutics and clinical risk management 20070801
Adherence, virological and immunological outcomes for HIV-infected veterans starting combination antiretroviral therapies. AIDS (London, England) 20070731
Efavirenz to nevirapine switch in HIV-1-infected patients with dyslipidemia: a randomized, controlled study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070715
[Insulin resistance in HIV-infected patients receiving long-term therapy with efavirenz, lopinavir/ritonavir and atazanavir]. Medicina clinica 20070714
Abbott's AIDS fight-back. Nature 20070705
The acyclic nucleoside phosphonates from inception to clinical use: historical perspective. Antiviral research 20070701
A new methodology for the simulation of flexible protein-ligand interactions. Journal of molecular graphics & modelling 20070701
Efavirenz pharmacokinetics in HIV-1-infected children are associated with CYP2B6-G516T polymorphism. Journal of acquired immune deficiency syndromes (1999) 20070701
Early response to highly active antiretroviral therapy in HIV-1-infected Kenyan children. Journal of acquired immune deficiency syndromes (1999) 20070701
Pregnancy rates and birth outcomes among women on efavirenz-containing highly active antiretroviral therapy in Botswana. Journal of acquired immune deficiency syndromes (1999) 20070701
Methadone dosing strategies in HIV-infected injection drug users enrolled in a directly observed therapy program. Journal of acquired immune deficiency syndromes (1999) 20070701
Dynamics of 103K/N and 184M/V HIV-1 drug resistant populations: relative comparison in plasma virus RNA versus CD45RO+T cell proviral DNA. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20070701
Effects of potent antiretroviral therapy on free testosterone levels and fat-free mass in men in a prospective, randomized trial: A5005s, a substudy of AIDS Clinical Trials Group Study 384. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070701
Polymorphic CYP2B6: molecular mechanisms and emerging clinical significance. Pharmacogenomics 20070701
Comparison of the effectiveness of initial combined antiretroviral therapy with nelfinavir or efavirenz at a university-based outpatient service in Brazil. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20070701
The first once-daily single-tablet regimen for the treatment of HIV-infected patients. Drugs of today (Barcelona, Spain : 1998) 20070701
Alopecia induced by lopinavir plus ritonavir therapy in an HIV patient. Journal of drugs in dermatology : JDD 20070701
Antiretroviral therapy during tuberculosis treatment and marked reduction in death rate of HIV-infected patients, Thailand. Emerging infectious diseases 20070701
Disseminated histoplasmosis and tuberculosis in a patient with HIV infection. Yonsei medical journal 20070630
Distinct roles for LINE-1 and HERV-K retroelements in cell proliferation, differentiation and tumor progression. Oncogene 20070621
Hepatotoxicity in an African antiretroviral therapy cohort: the effect of tuberculosis and hepatitis B. AIDS (London, England) 20070619
Misleading results of screening for illicit drugs during efavirenz treatment. AIDS (London, England) 20070619
Efavirenz: innocent bystander or direct nephrotoxin? AIDS (London, England) 20070619
Development of written information for antiretroviral therapy: comprehension in a Tanzanian population. Pharmacy world & science : PWS 20070601
Role of antiretroviral treatment in prolonging QTc interval in HIV-positive patients. The Journal of infection 20070601
Constant mitochondrial DNA levels in blood leukocytes of patients enrolled in a NRTI-free therapeutic trial (BIKS-2 study). The Journal of infection 20070601
Variability in non-nucleoside reverse transcriptase and protease inhibitors concentrations among HIV-infected adults in routine clinical practice. British journal of clinical pharmacology 20070601
High prevalence of subtherapeutic plasma concentrations of efavirenz in children. Journal of acquired immune deficiency syndromes (1999) 20070601
Efavirenz. Expert opinion on pharmacotherapy 20070601
Switching to a protease inhibitor-containing, nucleoside-sparing regimen (lopinavir/ritonavir plus efavirenz) increases limb fat but raises serum lipid levels: results of a prospective randomized trial (AIDS clinical trial group 5125s). Journal of acquired immune deficiency syndromes (1999) 20070601
Impact of CYP2B6 polymorphism on hepatic efavirenz metabolism in vitro. Pharmacogenomics 20070601
Antiretroviral pharmacokinetic profile: a review of sex differences. Gender medicine 20070601
Antiretroviral Drug Levels and Interactions Affect Lipid, Lipoprotein, and Glucose Metabolism in HIV-1 Seronegative Subjects: A Pharmacokinetic-Pharmacodynamic Analysis. Metabolic syndrome and related disorders 20070601
Alterations in circulating osteoimmune factors may be responsible for high bone resorption rate in HIV-infected children and adolescents. AIDS (London, England) 20070531
Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT. The Biochemical journal 20070515
Buprenorphine assay and plasma concentration monitoring in HIV-infected substance users. Journal of pharmaceutical and biomedical analysis 20070509
Novel CCR5 monoclonal antibodies with potent and broad-spectrum anti-HIV activities. Antiviral research 20070501
Determination of 19 antiretroviral agents in pharmaceuticals or suspected products with two methods using high-performance liquid chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501
Synthesis of novel diarylpyrimidine analogues of TMC278 and their antiviral activity against HIV-1 wild-type and mutant strains. European journal of medicinal chemistry 20070501
Effect of efavirenz on the pharmacokinetics of ketoconazole in HIV-infected patients. European journal of clinical pharmacology 20070501
No response to first-line tenofovir+lamivudine+efavirenz despite optimization according to baseline resistance testing: impact of resistant minority variants on efficacy of low genetic barrier drugs. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20070501
Association of serum lipid levels with HIV serostatus, specific antiretroviral agents, and treatment regimens. Journal of acquired immune deficiency syndromes (1999) 20070501
Synthesis and pharmacological activity of urea and thiourea derivatives of 4-azatricyclo[5.2.2.0(2,6)]undec-8-ene-3,5-dione. Chemical & pharmaceutical bulletin 20070501
Multiple-dose pharmacokinetics of efavirenz with and without the use of rifampicin in HIV-positive patients. Current HIV research 20070501
Discontinuation of non-nucleoside reverse transcriptase inhibitor-based highly active antiretroviral therapy due to nucleoside analogue reverse transcriptase inhibitor-related metabolic toxicity. International journal of STD & AIDS 20070501
Tenofovir disoproxil fumarate for prevention of HIV infection in women: a phase 2, double-blind, randomized, placebo-controlled trial. PLoS clinical trials 20070501
Emergence of NNRTI drug resistance mutations after single-dose nevirapine exposure in HIV type 1 subtype C-infected infants in India. AIDS research and human retroviruses 20070501
[Number and nature of drug interactions concerning antineoplastic drugs]. Bulletin du cancer 20070501
FDA notifications. FDA tentatively approves generic efavirenz. AIDS alert 20070501
Thailand: government issues compulsory licences for HIV/AIDS drugs. HIV/AIDS policy & law review 20070501
Intensification of a triple-nucleoside regimen with tenofovir or efavirenz in HIV-1-infected patients with virological suppression. AIDS (London, England) 20070423
Development of a competitive immunoassay for efavirenz: hapten design and validation studies. Analytica chimica acta 20070418
Metabolic effects of protease inhibitor-sparing antiretroviral regimens given as initial treatment of HIV-1 Infection (AIDS Clinical Trials Group Study A5095). Journal of acquired immune deficiency syndromes (1999) 20070415
Plasma HIV-1 RNA dynamics in antiretroviral-naive subjects receiving either triple-nucleoside or efavirenz-containing regimens: ACTG A5166s. The Journal of infectious diseases 20070415
Genetic variability of CYP2B6 polymorphisms in four southern Chinese populations. World journal of gastroenterology 20070414
Acyclic nucleoside phosphonates: past, present and future. Bridging chemistry to HIV, HBV, HCV, HPV, adeno-, herpes-, and poxvirus infections: the phosphonate bridge. Biochemical pharmacology 20070401
An isocratic liquid chromatography method for determining HIV non-nucleoside reverse transcriptase inhibitor and protease inhibitor concentrations in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070401
Predictive value of known and novel alleles of CYP2B6 for efavirenz plasma concentrations in HIV-infected individuals. Clinical pharmacology and therapeutics 20070401
Discovery of novel benzimidazolones as potent non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains. Bioorganic & medicinal chemistry letters 20070401
Clinical toxicity of highly active antiretroviral therapy in a home-based AIDS care program in rural Uganda. Journal of acquired immune deficiency syndromes (1999) 20070401
Slow-, tight-binding HIV-1 reverse transcriptase non-nucleoside inhibitors highly active against drug-resistant mutants. ChemMedChem 20070401
Influence of liver fibrosis stage on plasma levels of antiretroviral drugs in HIV-infected patients with chronic hepatitis C. The Journal of infectious diseases 20070401
ART suppresses plasma HIV-1 RNA to a stable set point predicted by pretherapy viremia. PLoS pathogens 20070401
Efavirenz: a review. Expert opinion on pharmacotherapy 20070401
Medicines Control Council and registration backlog of antiretrovirals. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20070401
NNRTI data in naive patients. AIDS patient care and STDs 20070401
FDA notifications. Sustiva packaging instructions updated. AIDS alert 20070401
Reinduction of cell differentiation and 131I uptake in a poorly differentiated thyroid tumor in response to the reverse transcriptase (RT) inhibitor nevirapine. Cancer biotherapy & radiopharmaceuticals 20070401
HIV-1 reverse transcriptase plus-strand initiation exhibits preferential sensitivity to non-nucleoside reverse transcriptase inhibitors in vitro. The Journal of biological chemistry 20070316
Hepatotoxicity due to a drug interaction between amodiaquine plus artesunate and efavirenz. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070315
High-performance liquid chromatography assay for the determination of the HIV-protease inhibitor tipranavir in human plasma in combination with nine other antiretroviral medications. Journal of pharmaceutical and biomedical analysis 20070312
Pharmacogenetics of antiretroviral drugs for the treatment of HIV-infected patients: an update. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20070301
Inhibition of MRP1/ABCC1, MRP2/ABCC2, and MRP3/ABCC3 by nucleoside, nucleotide, and non-nucleoside reverse transcriptase inhibitors. Drug metabolism and disposition: the biological fate of chemicals 20070301
Liver toxicity induced by non-nucleoside reverse transcriptase inhibitors. The Journal of antimicrobial chemotherapy 20070301
Once-daily highly active antiretroviral therapy for HIV-infected children: safety and efficacy of an efavirenz-containing regimen. Pediatrics 20070301
Dyslipidemia in an Asian population after treatment for two years with protease inhibitor-containing regimens. Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20070301
Quality of life and depression among HIV-infected patients receiving efavirenz- or protease inhibitor-based therapy in Senegal. HIV medicine 20070301
Neuropsychiatric side effects of efavirenz therapy. Expert opinion on drug safety 20070301
Factors in AIDS dementia complex trial design: results and lessons from the abacavir trial. PLoS clinical trials 20070301
New package inserts for efavirenz and T-20. AIDS clinical care 20070301
FDA notifications. FDA grants tentative approval of generic efavirenz. AIDS alert 20070301
Update on the CNS adverse effects of Sustiva (efavirenz). AIDS alert 20070301
Neurokinin-1 receptor antagonist (aprepitant) inhibits drug-resistant HIV-1 infection of macrophages in vitro. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20070301
Comparison of echinocandin antifungals. Therapeutics and clinical risk management 20070301
[Antiretrovirals]. Nihon rinsho. Japanese journal of clinical medicine 20070227
Thailand and the compulsory licensing of efavirenz. The New England journal of medicine 20070208
Less lipoatrophy and better lipid profile with abacavir as compared to stavudine: 96-week results of a randomized study. Journal of acquired immune deficiency syndromes (1999) 20070201
A novel nonnucleoside analogue that inhibits human immunodeficiency virus type 1 isolates resistant to current nonnucleoside reverse transcriptase inhibitors. Antimicrobial agents and chemotherapy 20070201
Structure-activity relationship in the 3-iodo-4-phenoxypyridinone (IOPY) series: The nature of the C-3 substituent on anti-HIV activity. Bioorganic & medicinal chemistry letters 20070201
Depo-medroxyprogesterone in women on antiretroviral therapy: effective contraception and lack of clinically significant interactions. Clinical pharmacology and therapeutics 20070201
Effects on growth after switching protease inhibitors to efavirenz in HIV-1-infected children. International journal of antimicrobial agents 20070201
Modulation of human BCRP (ABCG2) activity by anti-HIV drugs. The Journal of antimicrobial chemotherapy 20070201
Visual loss secondary to acquired immunodeficiency virus-related progressive multifocal leukoencephalopathy demonstrating clinical improvement with highly active antiretroviral therapy. Optometry (St. Louis, Mo.) 20070201
Efavirenz/emtricitabine/tenofovir disoproxil fumarate fixed-dose combination: first-line therapy for all? Expert opinion on pharmacotherapy 20070201
Transitory severe CNS adverse effects after accidental efavirenz overdose during post-exposure HIV prophylaxis. Journal of chemotherapy (Florence, Italy) 20070201
Update in HIV care. Journal of general internal medicine 20070201
Anti-HIV agents. New drugs, new hope, old lessons. TreatmentUpdate 20070201
Anti-HIV agents. American study finds efavirenz linked to fat wasting. TreatmentUpdate 20070201
Anti-HIV agents. A second study confirms fat loss issues with efavirenz. TreatmentUpdate 20070201
Anti-HIV agents. Efavirenz and fat wasting--what might be happening? TreatmentUpdate 20070201
Clinical and laboratory characteristics of hospitalised patients with neurological manifestations of HIV/AIDS at the Nairobi hospital. East African medical journal 20070201
Randomized open-label trial of two simplified, class-sparing regimens following a first suppressive three or four-drug regimen. AIDS (London, England) 20070130
Three-year follow-up of protease inhibitor-based regimen simplification in HIV-infected patients. AIDS (London, England) 20070130
Substrate-dependent inhibition or stimulation of HIV RNase H activity by non-nucleoside reverse transcriptase inhibitors (NNRTIs). Biochemical and biophysical research communications 20070112
Efavirenz-associated podocyte damage. AIDS (London, England) 20070111
[Treatment of HIV infection in 2006: highlights]. Revue medicale suisse 20070110
Efavirenz related compounds preparation by hydrolysis procedure: setting reference standards for chromatographic purity analysis. Journal of pharmaceutical and biomedical analysis 20070104
A mutagenetic tree hidden Markov model for longitudinal clonal HIV sequence data. Biostatistics (Oxford, England) 20070101
4-Aminopyrimidines as novel HIV-1 inhibitors. Bioorganic & medicinal chemistry letters 20070101
Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers. The Journal of pharmacology and experimental therapeutics 20070101
MALDI-TOF mass spectrometry for multiplex genotyping of CYP2B6 single-nucleotide polymorphisms. Clinical chemistry 20070101
Comparative biological and clinical outcomes after a switch from a virologically unsuccessful first protease inhibitor-containing antiretroviral combination to a 3-drug regimen containing efavirenz, nevirapine, or abacavir. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070101
HIV DNA and dementia in treatment-naïve HIV-1-infected individuals in Bangkok, Thailand. International journal of medical sciences 20070101
The emergence of HIV transmitted resistance in Botswana: 'when will the WHO detection threshold be exceeded?'. PloS one 20070101
A novel substrate-based HIV-1 protease inhibitor drug resistance mechanism. PLoS medicine 20070101
Non-nucleoside reverse transcriptase inhibitors: a review. International journal of clinical practice 20070101
Cost-effectiveness of genotypic antiretroviral resistance testing in HIV-infected patients with treatment failure. PloS one 20070101
Efavirenz and nevirapine in HIV-1 infection : is there a role for clinical pharmacokinetic monitoring? Clinical pharmacokinetics 20070101
Lack of indinavir-associated nephrological complications in HIV-infected adults (predominantly women) with high indinavir plasma concentration in Abidjan, Côte d'Ivoire. AIDS research and human retroviruses 20070101
Abacavir hypersensitivity reaction after switching from the twice-daily to the once-daily formulation. AIDS patient care and STDs 20070101
New pandemics: HIV and AIDS, HCV and chronic hepatitis, influenza virus and flu. Retrovirology 20070101
Schizophrenia, AIDS and the decision to prescribe HAART: results of a national survey of HIV clinicians. Journal of prevention & intervention in the community 20070101
Public health the leading force of the Indonesian response to the HIV/AIDS crisis among people who inject drugs. Harm reduction journal 20070101
Retroviral rebound syndrome after treatment discontinuation in a 15 year old girl with HIV attracted through mother-to-child transmission: case report. AIDS research and therapy 20070101
Methodological standards in non-inferiority AIDS trials: moving from adherence to compliance: response. BMC medical research methodology 20070101
Plasma nevirapine levels, adverse events and efficacy of antiretroviral therapy among HIV-infected patients concurrently receiving nevirapine-based antiretroviral therapy and fluconazole. BMC infectious diseases 20070101
Safety and efficacy of a generic fixed-dose combination of stavudine, lamivudine and nevirapine antiretroviral therapy between HIV-infected patients with baseline CD4 <50 versus CD4 > or = 50 cells/mm3. AIDS research and therapy 20070101
Poly (propyleneimine) dendrimer based nanocontainers for targeting of efavirenz to human monocytes/macrophages in vitro. Journal of drug targeting 20070101
Preliminary outcomes of a paediatric highly active antiretroviral therapy cohort from KwaZulu-Natal, South Africa. BMC pediatrics 20070101
HIV/AIDS drugs for Sub-Saharan Africa: how do brand and generic supply compare? PloS one 20070101
Pilot study of a novel short-cycle antiretroviral treatment interruption strategy: 48-week results of the five-days-on, two-days-off (FOTO) study. HIV clinical trials 20070101
How labour intensive is a doctor-based delivery model for antiretroviral treatment (ART)? Evidence from an observational study in Siem Reap, Cambodia. Human resources for health 20070101
The NEFA study: results at three years. AIDS reviews 20070101
Interpreting cerebrospinal fluid pleocytosis in HIV in the era of potent antiretroviral therapy. BMC infectious diseases 20070101
Dideoxynucleoside HIV reverse transcriptase inhibitors and drug-related hepatotoxicity: a case report. Journal of medical case reports 20070101
Predictors of disease progression in HIV infection: a review. AIDS research and therapy 20070101
A computer-based system to aid in the interpretation of plasma concentrations of antiretrovirals for therapeutic drug monitoring. Antiviral therapy 20070101
Does tenofovir influence efavirenz pharmacokinetics? Antiviral therapy 20070101
Plasma levels of soluble urokinase-type plasminogen activator receptor (suPAR) and early mortality risk among patients enrolling for antiretroviral treatment in South Africa. BMC infectious diseases 20070101
TRIPS, the Doha declaration and paragraph 6 decision: what are the remaining steps for protecting access to medicines? Globalization and health 20070101
AIDS in the Third World: how to stop the HIV infection? Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie 20070101
Anti-HIV drugs. Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie 20070101
Healthcare utilization of patients accessing an African national treatment program. BMC health services research 20070101
BK virus associated meningoencephalitis in an AIDS patient treated with HAART. AIDS research and therapy 20070101
Normalization of fat accrual in lipoatrophic, HIV-infected children switched from stavudine to tenofovir and from protease inhibitor to efavirenz. Antiviral therapy 20070101
First-line highly active antiretroviral regimens in 2001-2002 in the French Hospital Database on HIV: combination prescribed and biological outcomes. Antiviral therapy 20070101
Five-year follow up of once-daily therapy with emtricitabine, didanosine and efavirenz (Montana ANRS 091 trial). Antiviral therapy 20070101
Didanosine enteric-coated capsule: current role in patients with HIV-1 infection. Drugs 20070101
Fast and simultaneous determination of darunavir and eleven other antiretroviral drugs for therapeutic drug monitoring: method development and validation for the determination of all currently approved HIV protease inhibitors and non-nucleoside reverse transcriptase inhibitors in human plasma by liquid chromatography coupled with electrospray ionization tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20070101
Protease inhibitor associated mutations compromise the efficacy of therapy in human immunodeficiency virus-1 (HIV-1) infected pediatric patients: a cross-sectional study. AIDS research and therapy 20070101
The safety and efficacy of tenofovir DF in combination with lamivudine and efavirenz through 6 years in antiretroviral-naïve HIV-1-infected patients. HIV clinical trials 20070101
Electrospray tandem mass spectroscopic characterisation of 18 antiretroviral drugs and simultaneous quantification of 12 antiretrovirals in plasma. Rapid communications in mass spectrometry : RCM 20070101
Primary T-cells from human CD4/CCR5-transgenic rats support all early steps of HIV-1 replication including integration, but display impaired viral gene expression. Retrovirology 20070101
Validation of the SCID-hu Thy/Liv mouse model with four classes of licensed antiretrovirals. PloS one 20070101
Pharmacokinetic interaction between TMC114/r and efavirenz in healthy volunteers. Antiviral therapy 20070101
Differential drug resistance acquisition in HIV-1 of subtypes B and C. PloS one 20070101
Quadruple nucleoside therapy with zidovudine, lamivudine, abacavir and tenofovir in the treatment of HIV. Antiviral therapy 20070101
Substitutions due to antiretroviral toxicity or contraindication in the first 3 years of antiretroviral therapy in a large South African cohort. Antiviral therapy 20070101
Comparative efficacy of nucleoside/nucleotide reverse transcriptase inhibitors in combination with efavirenz: results of a systematic overview. HIV clinical trials 20070101
Access, use and perceptions regarding Internet, cell phones and PDAs as a means for health promotion for people living with HIV in Peru. BMC medical informatics and decision making 20070101
Policy maker and health care provider perspectives on reproductive decision-making amongst HIV-infected individuals in South Africa. BMC public health 20070101
Effect of highly active antiretroviral therapy on tacrolimus pharmacokinetics in hepatitis C virus and HIV co-infected liver transplant recipients in the ANRS HC-08 study. Clinical pharmacokinetics 20070101
Amprenavir and lopinavir pharmacokinetics following coadministration of amprenavir or fosamprenavir with lopinavir/ritonavir, with or without efavirenz. Antiviral therapy 20070101
Mycobacterium avium complex immune reconstitution inflammatory syndrome: long term outcomes. Journal of translational medicine 20070101
Utilization and spending trends for antiretroviral medications in the U.S. Medicaid program from 1991 to 2005. AIDS research and therapy 20070101
Effectiveness and safety of simplification therapy with once-daily tenofovir, lamivudine, and efavirenz in HIV-1-infected patients with undetectable plasma viral load on HAART. HIV clinical trials 20070101
The association of bone mineral density with HIV infection and antiretroviral treatment in women. Antiviral therapy 20070101
Cost-effectiveness of tipranavir versus comparator protease inhibitor regimens in HIV infected patients previously exposed to antiretroviral therapy in the Netherlands. Cost effectiveness and resource allocation : C/E 20070101
Anti-HIV agents. Using maraviroc in first-line therapy. TreatmentUpdate 20070101
The safety and efficacy of switching stavudine to tenofovir df in combination with lamivudine and efavirenz in hiv-1-infected patients: three-year follow-up after switching therapy. HIV clinical trials 20070101
[Intestinal microbiota of individuals who suffered occupational accidents with biological materials and underwent antiretroviral prophylaxis]. Revista da Sociedade Brasileira de Medicina Tropical 20070101
Lipodystrophy and metabolic changes in HIV-infected children on non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy. Antiviral therapy 20070101
Relationships between drug exposure, changes in metabolic parameters and body fat in HIV-infected patients switched to a nucleoside sparing regimen. Antiviral therapy 20070101
Poor efficacy and tolerability of stavudine, didanosine, and efavirenz-based regimen in treatment-naive patients in Senegal. MedGenMed : Medscape general medicine 20070101
[Pilot study of antiretroviral therapy in Djibouti]. Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit 20070101
Active methamphetamine use is associated with transmitted drug resistance to non-nucleoside reverse transcriptase inhibitors in individuals with HIV infection of unknown duration. The open AIDS journal 20070101
A cluster-randomised trial to compare home-based with health facility-based antiretroviral treatment in Uganda: study design and baseline findings. The open AIDS journal 20070101
Clinical implications of mutations at reverse transcriptase codon 135 on response to NNRTI-based therapy. The open virology journal 20070101
Poor Efficacy and Tolerability of Stavudine, Didanosine, and Efavirenz-based Regimen in Treatment-Naive Patients in Senegal. Journal of the International AIDS Society 20070101
Anidulafungin: an evidence-based review of its use in invasive fungal infections. Core evidence 20070101
Maraviroc: the evidence for its potential in the management of HIV. Core evidence 20070101
Targeting human immunodeficiency virus type 1 assembly, maturation and budding. Drug target insights 20070101
Tenofovir disoproxil fumarate, emtricitabine, and efavirenz versus fixed-dose zidovudine/lamivudine and efavirenz in antiretroviral-naive patients: virologic, immunologic, and morphologic changes--a 96-week analysis. Journal of acquired immune deficiency syndromes (1999) 20061215
Interactions between buprenorphine and antiretrovirals. I. The nonnucleoside reverse-transcriptase inhibitors efavirenz and delavirdine. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20061215
Antiretroviral activity, pharmacokinetics, and tolerability of MK-0518, a novel inhibitor of HIV-1 integrase, dosed as monotherapy for 10 days in treatment-naive HIV-1-infected individuals. Journal of acquired immune deficiency syndromes (1999) 20061215
Administration of efavirenz (600 mg/day) with rifampicin results in highly variable levels but excellent clinical outcomes in patients treated for tuberculosis and HIV. The Journal of antimicrobial chemotherapy 20061201
Highly active antiretroviral treatment containing efavirenz or nevirapine and related toxicity in the TREAT Asia HIV Observational Database. Journal of acquired immune deficiency syndromes (1999) 20061201
Evaluation of 227 drugs for in vitro inhibition of cytochrome P450 2B6. Journal of clinical pharmacology 20061201
Lack of mucosal immune reconstitution during prolonged treatment of acute and early HIV-1 infection. PLoS medicine 20061201
Didanosine, lamivudine-emtricitabine and efavirenz as initial therapy in naive patients. Expert review of anti-infective therapy 20061201
Atripla approval in Europe. AIDS patient care and STDs 20061201
Meeting report. Report from ICAAC. AIDS clinical care 20061201
Nevirapine versus efavirenz based antiretroviral treatment in naive Indian patients: comparison of effectiveness in clinical cohort. The Journal of the Association of Physicians of India 20061201
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Full validation of an analytical method for the HIV-protease inhibitor atazanavir in combination with 8 other antiretroviral agents and its applicability to therapeutic drug monitoring. Therapeutic drug monitoring 20060801
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Structural insights into mechanisms of non-nucleoside drug resistance for HIV-1 reverse transcriptases mutated at codons 101 or 138. The FEBS journal 20060801
Computer-aided molecular design of highly potent HIV-1 RT inhibitors: 3D QSAR and molecular docking studies of efavirenz derivatives. SAR and QSAR in environmental research 20060801
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A comparison between abacavir and efavirenz as the third drug used in combination with a background therapy regimen of 2 nucleoside reverse-transcriptase inhibitors in patients with initially suppressed viral loads. The Journal of infectious diseases 20060701
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Influence of tenofovir, nevirapine and efavirenz on ritonavir-boosted atazanavir pharmacokinetics in HIV-infected patients. European journal of clinical pharmacology 20060701
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Modulation of human immunodeficiency virus type 1 synergistic inhibition by reverse transcriptase mutations. Biochemistry 20060613
A case of voluntary intoxication with efavirenz and lamivudine. AIDS (London, England) 20060612
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Antiretroviral drug resistance and routine therapy, Cameroon. Emerging infectious diseases 20060601
Oral absorption of poorly water-soluble drugs: computer simulation of fraction absorbed in humans from a miniscale dissolution test. Pharmaceutical research 20060601
Design, molecular modeling, synthesis, and anti-HIV-1 activity of new indolyl aryl sulfones. Novel derivatives of the indole-2-carboxamide. Journal of medicinal chemistry 20060601
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Haemolytic anaemia associated with efavirenz. AIDS (London, England) 20060512
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Simple and rapid liquid chromatography method for determination of efavirenz in plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060501
Frequency and treatment-related predictors of thymidine-analogue mutation patterns in HIV-1 isolates after unsuccessful antiretroviral therapy. The Journal of infectious diseases 20060501
Changes in sleep quality and brain wave patterns following initiation of an efavirenz-containing triple antiretroviral regimen. HIV medicine 20060501
Characterization of interference with 6 commercial delta9-tetrahydrocannabinol immunoassays by efavirenz (glucuronide) in urine. Clinical chemistry 20060501
Efficacy and safety of an anti-retroviral combination regimen including either efavirenz or lopinavir-ritonavir with a backbone of two nucleoside reverse transcriptase inhibitors. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20060501
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Response to: Are all non-thymidine analogue backbones appropriate for treating antiretroviral-naïve patients? International journal of clinical practice 20060501
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Tolerance and acceptability of an efavirenz-based regimen in 740 adults (predominantly women) in West Africa. Journal of acquired immune deficiency syndromes (1999) 20060501
[Evolution of mortality and current status of an HIV-infected population cared for at a comprehensive HIV/AIDS center in Chile]. Revista medica de Chile 20060501
Towards discovering dual functional inhibitors against both wild type and K103N mutant HIV-1 reverse transcriptases: molecular docking and QSAR studies on 4,1-benzoxazepinone analogues. Journal of computer-aided molecular design 20060501
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Antiretroviral medications associated with elevated blood pressure among patients receiving highly active antiretroviral therapy. AIDS (London, England) 20060424
Maintenance of successful ritonavir-boosted indinavir and efavirenz therapy in an HIV-infected patient with tuberculosis. AIDS (London, England) 20060424
Biosensor-based kinetic characterization of the interaction between HIV-1 reverse transcriptase and non-nucleoside inhibitors. Journal of medicinal chemistry 20060420
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Effect of co-trimoxazole prophylaxis, antiretroviral therapy, and insecticide-treated bednets on the frequency of malaria in HIV-1-infected adults in Uganda: a prospective cohort study. Lancet (London, England) 20060415
Mixed patterns of changes in central and peripheral fat following initiation of antiretroviral therapy in a randomized trial. Journal of acquired immune deficiency syndromes (1999) 20060415
Genital HIV-1 viral load is correlated with blood plasma HIV-1 viral load in Brazilian women and is reduced by antiretroviral therapy. The Journal of infection 20060401
Synthesis and anti-HIV activity of new alkenyldiarylmethane (ADAM) non-nucleoside reverse transcriptase inhibitors (NNRTIs) incorporating benzoxazolone and benzisoxazole rings. Bioorganic & medicinal chemistry 20060401
Use of tenofovir disoproxil fumarate and emtricitabine combination in HIV-infected patients. Expert opinion on pharmacotherapy 20060401
The effects of the Roche AMPLICOR HIV-1 MONITOR UltraSensitive Test versions 1.0 and 1.5 viral load assays and plasma collection tube type on determination of response to antiretroviral therapy and the inappropriateness of cross-study comparisons. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20060401
Nonnucleoside reverse transcriptase inhibitor fold change or plasma concentration as a predictor of virological response over 48 weeks in highly treatment experienced HIV-positive individuals. AIDS research and human retroviruses 20060401
Comparative bioavailability of a generic capsule formulation of the reverse transcriptase inhibitor efavirenz and the innovator product. International journal of clinical pharmacology and therapeutics 20060401
False-positive results in urine drug screening in healthy volunteers participating in phase 1 studies with efavirenz and rifampin. Therapeutic drug monitoring 20060401
Pharmacologic optimization of protease inhibitors and nonnucleoside reverse transcriptase inhibitors (POPIN)--a randomized controlled trial of therapeutic drug monitoring and adherence support. Journal of acquired immune deficiency syndromes (1999) 20060401
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Report from the 13th retrovirus conference. Vicriviroc less effective than efavirenz in treatment-naive patients. AIDS clinical care 20060401
[Severe psychosis in an African woman due to the antiretroviral agent efavirenz]. Nederlands tijdschrift voor geneeskunde 20060318
[Severe psychosis in an African woman due to the antiretroviral agent efavirenz]. Nederlands tijdschrift voor geneeskunde 20060318
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Initiation of antiretroviral therapy in advanced AIDS with active tuberculosis: clinical experiences from Thailand. The Journal of infection 20060301
Influence of HCV or HBV coinfection on adverse drug reactions to antiretroviral drugs in HIV patients. European journal of clinical pharmacology 20060301
Associations among race/ethnicity, ApoC-III genotypes, and lipids in HIV-1-infected individuals on antiretroviral therapy. PLoS medicine 20060301
Antiretroviral therapy and dyslipidaemia: unlocking the code. PLoS medicine 20060301
HIV-related neutropaenia exacerbated by efavirenz. HIV medicine 20060301
Identification of a novel specific CYP2B6 allele in Africans causing impaired metabolism of the HIV drug efavirenz. Pharmacogenetics and genomics 20060301
Effect of buprenorphine and antiretroviral agents on the QT interval in opioid-dependent patients. The Annals of pharmacotherapy 20060301
Pharmacokinetic parameters of nevirapine and efavirenz in relation to antiretroviral efficacy. AIDS research and human retroviruses 20060301
Phenotypic drug resistance patterns in subtype A HIV-1 clones with nonnucleoside reverse transcriptase resistance mutations. AIDS research and human retroviruses 20060301
API TB Consensus Guidelines 2006: Management of pulmonary tuberculosis, extra-pulmonary tuberculosis and tuberculosis in special situations. The Journal of the Association of Physicians of India 20060301
Determination of the novel non-peptidic HIV-protease inhibitor tipranavir by HPLC-UV after solid-phase extraction. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060217
Major role of hepatitis B genotypes in liver fibrosis during coinfection with HIV. AIDS (London, England) 20060214
Simultaneous determination of 16 anti-HIV drugs in human plasma by high-performance liquid chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060202
Severe efavirenz-induced hypersensitivity syndrome (not-DRESS) with acute renal failure. The Journal of infection 20060201
Pharmacogenetics of plasma efavirenz exposure after treatment discontinuation: an Adult AIDS Clinical Trials Group Study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060201
Efavirenz and CYP2B6 polymorphism: implications for drug toxicity and resistance. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060201
HIV-1 reverse transcriptase gene 103K/N and 184M/V combinations in tandem: detection and quantification of HIV-1 populations in the CD45RO+ T-cell compartment by a double-ARMS real-time PCR assay. Journal of acquired immune deficiency syndromes (1999) 20060201
Interpatient variability in the pharmacokinetics of the HIV non-nucleoside reverse transcriptase inhibitor efavirenz: the effect of gender, race, and CYP2B6 polymorphism. British journal of clinical pharmacology 20060201
Study of efavirenz over 96 weeks shows durability, efficacious regimen. Results from 48-96 weeks essentially same. AIDS alert 20060201
Structure-activity relationship studies of novel benzophenones leading to the discovery of a potent, next generation HIV nonnucleoside reverse transcriptase inhibitor. Journal of medicinal chemistry 20060126
Tenofovir DF, emtricitabine, and efavirenz vs. zidovudine, lamivudine, and efavirenz for HIV. The New England journal of medicine 20060119
Body fat and other metabolic effects of atazanavir and efavirenz, each administered in combination with zidovudine plus lamivudine, in antiretroviral-naive HIV-infected patients. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060115
Economic impact of antiretroviral therapy prescription decisions in the context of rapid scaling-up of access to treatment: lessons from Mexico. AIDS (London, England) 20060102
Efavirenz 600 mg/day versus efavirenz 800 mg/day in HIV-infected patients with tuberculosis receiving rifampicin: 48 weeks results. AIDS (London, England) 20060102
Simultaneous determination of six HIV protease inhibitors (amprenavir, indinavir, lopinavir, nelfinavir, ritonavir and saquinavir), the active metabolite of nelfinavir (M8) and non-nucleoside reverse transcriptase inhibitor (efavirenz) in human plasma by high-performance liquid chromatography. Biomedical chromatography : BMC 20060101
Assessment of drug-drug interactions between tenofovir disoproxil fumarate and the nonnucleoside reverse transcriptase inhibitors nevirapine and efavirenz in HIV-infected patients. Journal of acquired immune deficiency syndromes (1999) 20060101
Reasons for modification of generic highly active antiretroviral therapeutic regimens among patients in southern India. Journal of acquired immune deficiency syndromes (1999) 20060101
Population pharmacokinetics of efavirenz in an unselected cohort of HIV-1-infected individuals. Clinical pharmacokinetics 20060101
Better quality of life with neuropsychological improvement on HAART. Health and quality of life outcomes 20060101
Understanding and avoiding antiretroviral adverse events. Current pharmaceutical design 20060101
Increased antiretroviral potency by the addition of enfuvirtide to a four-drug regimen in antiretroviral-naive, HIV-infected patients. Antiviral therapy 20060101
An open-label, randomized comparative pilot study of a single-class quadruple therapy regimen versus a 2-class triple therapy regimen for individuals initiating antiretroviral therapy. Antiviral therapy 20060101
Direct and fast determination of antiretroviral drugs by automated online solid-phase extraction-liquid chromatography-tandem mass spectrometry in human plasma. Clinical chemistry and laboratory medicine 20060101
DR_SEQAN: a PC/Windows-based software to evaluate drug resistance using human immunodeficiency virus type 1 genotypes. BMC infectious diseases 20060101
[Neuro-psychiatric adverse effects associated with efavirenz]. Enfermedades infecciosas y microbiologia clinica 20060101
CD4 cell count recovery among HIV-infected patients with very advanced immunodeficiency commencing antiretroviral treatment in sub-Saharan Africa. BMC infectious diseases 20060101
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Cerebrospinal fluid HIV-1 RNA, intrathecal immunoactivation, and drug concentrations after treatment with a combination of saquinavir, nelfinavir, and two nucleoside analogues: the M61022 study. BMC infectious diseases 20060101
Antiretroviral therapy at a district hospital in Ethiopia prevents death and tuberculosis in a cohort of HIV patients. AIDS research and therapy 20060101
Efavirenz use during pregnancy and for women of child-bearing potential. AIDS research and therapy 20060101
Neuropsychiatric adverse events after switching from an antiretroviral regimen containing efavirenz without tenofovir to an efavirenz regimen containing tenofovir: a report of nine cases. Antiviral therapy 20060101
API consensus guidelines for use of antiretroviral therapy in adults (API-ART guidelines). Endorsed by the AIDS Society of India. The Journal of the Association of Physicians of India 20060101
Pulmonary thromboembolism in AIDS patient with chronic venous insufficiency, pulmonary tuberculosis and breast cancer: a case report and pathophysiology review. Revista do Instituto de Medicina Tropical de Sao Paulo 20060101
Affective disorders in patients with HIV infection: impact of antiretroviral therapy. CNS drugs 20060101
Treating HIV during pregnancy: an update on safety issues. Drug safety 20060101
Concentration of circulating oxidized LDL in HIV-infected patients treated with antiretroviral agents: relation to HIV-related lipodystrophy. HIV clinical trials 20060101
Tipranavir: a novel nonpeptidic protease inhibitor of HIV. Clinical pharmacokinetics 20060101
[Efavirenz (Sustiva) in pregnancy: a study about 12 HIV patients]. Gynecologie, obstetrique & fertilite 20060101
Burning mouth syndrome due to efavirenz therapy. The Annals of pharmacotherapy 20060101
Lopinavir/ritonavir: a review of its use in the management of HIV infection. Drugs 20060101
Effects of highly active antiretroviral therapy with nelfinavir in vertically HIV-1 infected children: 3 years of follow-up. Long-term response to nelfinavir in children. BMC infectious diseases 20060101
Genotyping of CYP2B6 and therapeutic drug monitoring in an HIV-infected patient with high efavirenz plasma concentrations and severe CNS side-effects. Scandinavian journal of infectious diseases 20060101
The effect of different combination therapies on oxidative stress markers in HIV infected patients in Cameroon. AIDS research and therapy 20060101
Efavirenz/emtricitabine/tenofovir disoproxil fumarate: triple combination tablet. Drugs 20060101
Local tumor control and toxicity in HIV-associated anal carcinoma treated with radiotherapy in the era of antiretroviral therapy. Radiation oncology (London, England) 20060101
Efficacy, safety and pharmacokinetics of once-daily saquinavir soft-gelatin capsule/ritonavir in antiretroviral-naive, HIV-infected patients. MedGenMed : Medscape general medicine 20060101
Long-term safety and tolerability of the lamivudine/abacavir combination as components of highly active antiretroviral therapy. Drug safety 20060101
Predictors of early death in a cohort of Ethiopian patients treated with HAART. BMC infectious diseases 20060101
Lopinavir/ritonavir or efavirenz plus two nucleoside analogues as first-line antiretroviral therapy: a non-randomized comparison. Antiviral therapy 20060101
Neuropsychiatric complications of antiretroviral therapy. Drug safety 20060101
Cytotoxic T cell recognition of an HIV-1 reverse transcriptase variant peptide incorporating the K103N drug resistance mutation. AIDS research and therapy 20060101
Indolyl aryl sulphones as HIV-1 non-nucleoside reverse transcriptase inhibitors: synthesis, biological evaluation and binding mode studies of new derivatives at indole-2-carboxamide. Antiviral chemistry & chemotherapy 20060101
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[Methadone: from pharmacokinetic profile to clinical pharmacology]. L'Encephale 20060101
Nucleoside analogue reverse transcriptase inhibitor options: a re-examination of the class. Topics in HIV medicine : a publication of the International AIDS Society, USA 20060101
The cost-effectiveness of antiretroviral treatment in Khayelitsha, South Africa--a primary data analysis. Cost effectiveness and resource allocation : C/E 20060101
Can efavirenz be taken in the morning? Scandinavian journal of infectious diseases 20060101
An immunological comparison of third companion in advanced drug-naive HIV-infected patients. HIV clinical trials 20060101
Pilot study of once-daily simplification therapy with abacavir/lamivudine/zidovudine and efavirenz for treatment of HIV-1 infection. HIV clinical trials 20060101
Tuberculosis and HIV co-infection: a practical therapeutic approach. Drugs 20060101
Strong HIV-1-specific T cell responses in HIV-1-exposed uninfected infants and neonates revealed after regulatory T cell removal. PloS one 20060101
A comparative study on the cost of new antibiotics and drugs of other therapeutic categories. PloS one 20060101
Clinical outcome of HIV-infected patients with sustained virologic response to antiretroviral therapy: long-term follow-up of a multicenter cohort. PloS one 20060101
Use of taste-masking product, FLAVORx, to assist Thai children to ingest generic antiretrovirals. AIDS research and therapy 20060101
No virological failure in semen during properly suppressive antiretroviral therapy despite subtherapeutic local drug concentrations. HIV clinical trials 20060101
Cost to achieve an undetectable viral load using recommended antiretroviral regimens. HIV clinical trials 20060101
Synthesis of amino derivatives of 10-(diphenylmethylene)-4-azatricyclo[5.2.1.0(2,6)]dec-8-ene-3,5-dione as potential psychotropic and/or anti HIV agents. Acta poloniae pharmaceutica 20060101
Anti-HIV agents. Some drug interactions with Merck's integrase inhibitor. TreatmentUpdate 20060101
Drug interactions. Super pills-the treatments of the future? TreatmentUpdate 20060101
Switching strategies to improve lipid profile and morphologic changes. AIDS reviews 20060101
Antiretroviral therapy at conception in pregnant women with HIV in Italy: wide range of variability and frequent exposure to contraindicated drugs. Antiviral therapy 20060101
Rare selection of the K65R mutation in antiretroviral-naive patients failing a first-line abacavir/ lamivudine-containing HAART regimen. Antiviral therapy 20060101
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Sustiva: revised drug-interaction information. AIDS treatment news 20060101
Disease Management - Constructing Optimal NRTI-Based Combinations: Past, Present, and Future. Journal of the International AIDS Society 20060101
Neurocognitive deficits in HIV-positive patients-two case reports: Revising current AANTF guidelines in view of recent revelation of new neurocognitive symptoms. Indian journal of psychiatry 20060101
The Chilean AIDS cohort: a model for evaluating the impact of an expanded access program to antiretroviral therapy in a middle-income country--organization and preliminary results. Journal of acquired immune deficiency syndromes (1999) 20051215
Efficacy of cerebrospinal fluid (CSF)-penetrating antiretroviral drugs against HIV in the neurological compartment: different patterns of phenotypic resistance in CSF and plasma. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20051215
Spontaneous hepatic decompensation in patients coinfected with HIV and hepatitis C virus during interferon-ribavirin combination treatment. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20051215
Parallel solution-phase and microwave-assisted synthesis of new S-DABO derivatives endowed with subnanomolar anti-HIV-1 activity. Journal of medicinal chemistry 20051215
Effect of first line therapy including efavirenz and two nucleoside reverse transcriptase inhibitors in HIV-infected children. European journal of medical research 20051207
Prediction of neuropsychiatric adverse events associated with long-term efavirenz therapy, using plasma drug level monitoring. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20051201
Early virologic nonresponse to tenofovir, abacavir, and lamivudine in HIV-infected antiretroviral-naive subjects. The Journal of infectious diseases 20051201
Pharmacogenetics of long-term responses to antiretroviral regimens containing Efavirenz and/or Nelfinavir: an Adult Aids Clinical Trials Group Study. The Journal of infectious diseases 20051201
Genetic variability of CYP2B6 in populations of African and Asian origin: allele frequencies, novel functional variants, and possible implications for anti-HIV therapy with efavirenz. Pharmacogenetics and genomics 20051201
Assessment of adherence to highly active antiretroviral therapy in a cohort of African HIV-infected children in Abidjan, Côte d'Ivoire. Journal of acquired immune deficiency syndromes (1999) 20051201
Allosteric modulation of anti-HIV drug and ferric heme binding to human serum albumin. The FEBS journal 20051201
Genotypic human immunodeficiency virus type 1 drug resistance in highly active antiretroviral therapy-treated children in Abidjan, Côte d'Ivoire. The Pediatric infectious disease journal 20051201
Stevens - Johnson syndrome due to nevirapine. African health sciences 20051201
HIV infection. Clinical evidence 20051201
[Severe psychosis in an African woman due to the antiretroviral agent efavirenz]. Nederlands tijdschrift voor geneeskunde 20051126
Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity. Journal of medicinal chemistry 20051117
Mitochondrial DNA and RNA increase in peripheral blood mononuclear cells from HIV-1-infected patients randomized to receive stavudine-containing or stavudine-sparing combination therapy. The Journal of infectious diseases 20051115
Summaries for patients. Neuropsychological side effects of efavirenz. Annals of internal medicine 20051115
Impact of efavirenz on neuropsychological performance and symptoms in HIV-infected individuals. Annals of internal medicine 20051115
Glucose metabolism, lipid, and body fat changes in antiretroviral-naive subjects randomized to nelfinavir or efavirenz plus dual nucleosides. AIDS (London, England) 20051104
Evaluation of the drug interaction between rifabutin and efavirenz in patients with HIV infection and tuberculosis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20051101
Initial response to highly active antiretroviral therapy in HIV-1C-infected adults in a public sector treatment program in Botswana. Journal of acquired immune deficiency syndromes (1999) 20051101
Anti-human immunodeficiency virus type 1 activity of the nonnucleoside reverse transcriptase inhibitor GW678248 in combination with other antiretrovirals against clinical isolate viruses and in vitro selection for resistance. Antimicrobial agents and chemotherapy 20051101
High potency of indolyl aryl sulfone nonnucleoside inhibitors towards drug-resistant human immunodeficiency virus type 1 reverse transcriptase mutants is due to selective targeting of different mechanistic forms of the enzyme. Antimicrobial agents and chemotherapy 20051101
Prenatal exposure to fluconazole: an identifiable dysmorphic phenotype. Birth defects research. Part A, Clinical and molecular teratology 20051101
Triple nucleoside reverse transcriptase inhibitor- vs. nonnucleoside reverse transcriptase inhibitor-containing regimens as first-line therapy: efficacy and durability in a prospective cohort of French HIV-infected patients. HIV medicine 20051101
Impact of antiretroviral choice on hypercholesterolaemia events: the role of the nucleoside reverse transcriptase inhibitor backbone. HIV medicine 20051101
Drug-resistance mutations in antiretroviral-naïve patients with established HIV-1 infection in Mexico. HIV medicine 20051101
Indinavir/ritonavir 800/100 mg bid and efavirenz 600 mg qd in patients failing treatment with combination nucleoside reverse transcriptase inhibitors: 96-week outcomes of HIV-NAT 009. HIV medicine 20051101
Neuropsychiatric effects of efavirenz: delayed onset. International journal of STD & AIDS 20051101
Antiretroviral treatment in the Northern Cape. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20051101
Synthesis and evaluation of anti-HIV activity of isatin beta-thiosemicarbazone derivatives. Bioorganic & medicinal chemistry letters 20051015
Gilbert syndrome and the development of antiretroviral therapy-associated hyperbilirubinemia. The Journal of infectious diseases 20051015
The rate of viral rebound after attainment of an HIV load <50 copies/mL according to specific antiretroviral drugs in use: results from a multicenter cohort study. The Journal of infectious diseases 20051015
Efavirenz detectable in plasma 8 weeks after stopping therapy and subsequent development of non-nucleoside reverse transcriptase inhibitor-associated resistance. AIDS (London, England) 20051014
Determination of antiretroviral agents in human serum by capillary electrophoresis. Journal of chromatography. A 20051014
Reverse transcriptase inhibitors down-regulate cell proliferation in vitro and in vivo and restore thyrotropin signaling and iodine uptake in human thyroid anaplastic carcinoma. The Journal of clinical endocrinology and metabolism 20051001
Recreational substance use and tolerance of efavirenz in HIV-1 infected patients. AIDS care 20051001
Intracellular and plasma pharmacokinetics of efavirenz in HIV-infected individuals. The Journal of antimicrobial chemotherapy 20051001
Oxadiazols: a new class of rationally designed anti-human immunodeficiency virus compounds targeting the nuclear localization signal of the viral matrix protein. Journal of virology 20051001
Antiviral activity of GW678248, a novel benzophenone nonnucleoside reverse transcriptase inhibitor. Antimicrobial agents and chemotherapy 20051001
Meeting notes from the 3rd IAS Conference. Old drugs, new data. AIDS clinical care 20051001
Hopes dashed for formulation. AIDS patient care and STDs 20051001
Sequencing antiretroviral drugs for long-lasting suppression of HIV replication. The new microbiologica 20051001
Pharmacokinetic drug interactions with non-nucleoside reverse transcriptase inhibitors. Expert opinion on drug metabolism & toxicology 20051001
Efavirenz levels and 24-week efficacy in HIV-infected patients with tuberculosis receiving highly active antiretroviral therapy and rifampicin. AIDS (London, England) 20050923
Pharmacokinetic interactions between efavirenz and rifampicin in the treatment of HIV and tuberculosis: one size does not fit all. AIDS (London, England) 20050923
Mitochondrial haplogroups and peripheral neuropathy during antiretroviral therapy: an adult AIDS clinical trials group study. AIDS (London, England) 20050902
Genotypic and phenotypic resistance patterns at virological failure in a simplification trial with nevirapine, efavirenz or abacavir. AIDS (London, England) 20050902
[Rashes in HIV-infected patients undergoing therapy with nevirapine or efavirenz]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20050901
The role of Thr139 in the human immunodeficiency virus type 1 reverse transcriptase sensitivity to (+)-calanolide A. Molecular pharmacology 20050901
Risk factors for and outcome of hyperlactatemia in HIV-infected persons: is there a need for routine lactate monitoring? Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050901
Population pharmacokinetics of indinavir alone and in combination with ritonavir in HIV-1-infected patients. British journal of clinical pharmacology 20050901
Study of MMLV RT- binding with DNA using surface plasmon resonance biosensor. Acta biochimica et biophysica Sinica 20050901
Therapeutic drug monitoring of efavirenz: trough levels cannot be estimated on the basis of earlier plasma determinations. Journal of acquired immune deficiency syndromes (1999) 20050815
A K103N resistance mutation is not an absolute contraindication to adding efavirenz to a salvage regimen: a case report. AIDS (London, England) 20050812
Effect of efavirenz on intestinal p-glycoprotein and hepatic p450 function in rats. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20050804
Impact of rosiglitazone treatment on the bioavailability of antiretroviral compounds in HIV-positive patients. The Journal of antimicrobial chemotherapy 20050801
Determination of nevirapine and efavirenz in plasma using GC/MS in selected ion monitoring mode. Therapeutic drug monitoring 20050801
Myelomeningocele in an infant with intrauterine exposure to efavirenz. Journal of perinatology : official journal of the California Perinatal Association 20050801
Antiretroviral therapy in HIV-1 infected children. Indian pediatrics 20050801
Early virologic failure in HIV-1 infected subjects on didanosine/tenofovir/efavirenz: 12-week results from a randomized trial. AIDS (London, England) 20050722
A potentially significant interaction between efavirenz and phenytoin: a case report and review of the literature. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050715
Antiviral activity of lamivudine in salvage therapy for multidrug-resistant HIV-1 infection. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050715
The amino acid Asn136 in HIV-1 reverse transcriptase (RT) maintains efficient association of both RT subunits and enables the rational design of novel RT inhibitors. Molecular pharmacology 20050701
Exploratory analysis for the evaluation of lopinavir/ritonavir-versus efavirenz-based HAART regimens in antiretroviral-naive HIV-positive patients: results from the Italian MASTER Cohort. The Journal of antimicrobial chemotherapy 20050701
Efficacy of highly active antiretroviral therapy in HIV-infected children participating in Thailand's National Access to Antiretroviral Program. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050701
Substitution of nevirapine or efavirenz for protease inhibitor versus lipid-lowering therapy for the management of dyslipidaemia. AIDS (London, England) 20050701
HIV-1 intermittent viraemia in patients treated by non-nucleoside reverse transcriptase inhibitor-based regimen. AIDS (London, England) 20050701
Pharmacokinetic evidence for the induction of lopinavir metabolism by efavirenz. British journal of clinical pharmacology 20050701
Induction with abacavir/lamivudine/zidovudine plus efavirenz for 48 weeks followed by 48-week maintenance with abacavir/lamivudine/zidovudine alone in antiretroviral-naive HIV-1-infected patients. Journal of acquired immune deficiency syndromes (1999) 20050701
Efficacy and tolerability of a nucleoside reverse transcriptase inhibitor-sparing combination of lopinavir/ritonavir and efavirenz in HIV-1-infected patients. Journal of acquired immune deficiency syndromes (1999) 20050701
Effect of efavirenz on the pharmacokinetics of simvastatin, atorvastatin, and pravastatin: results of AIDS Clinical Trials Group 5108 Study. Journal of acquired immune deficiency syndromes (1999) 20050701
Conventional HPLC method used for simultaneous determination of the seven HIV protease inhibitors and nonnucleoside reverse transcription inhibitor efavirenz in human plasma. Biological & pharmaceutical bulletin 20050701
Effects on immunological and virological outcome of patients using one protease inhibitor or one non-nucleoside reverse transcriptase inhibitor in a triple antiretroviral therapy: normal clinical practice versus clinical trial findings. Current HIV research 20050701
Use of amitriptyline to offset sleep disturbances caused by efavirenz. AIDS patient care and STDs 20050701
Treatment of opioid dependence and coinfection with HIV and hepatitis C virus in opioid-dependent patients: the importance of drug interactions between opioids and antiretroviral agents. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050701
Novel 1-[2-(diarylmethoxy)ethyl]-2-methyl-5-nitroimidazoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. A structure-activity relationship investigation. Journal of medicinal chemistry 20050630
Identification of amino acid residues in the human immunodeficiency virus type-1 reverse transcriptase tryptophan-repeat motif that are required for subunit interaction using infectious virions. Journal of molecular biology 20050617
Metabolic benefits 24 months after replacing a protease inhibitor with abacavir, efavirenz or nevirapine. AIDS (London, England) 20050610
Inhibition of endogenous reverse transcriptase antagonizes human tumor growth. Oncogene 20050602
Structure-based design, parallel synthesis, structure-activity relationship, and molecular modeling studies of thiocarbamates, new potent non-nucleoside HIV-1 reverse transcriptase inhibitor isosteres of phenethylthiazolylthiourea derivatives. Journal of medicinal chemistry 20050602
The naturally occurring cytochrome P450 (P450) 2B6 K262R mutant of P450 2B6 exhibits alterations in substrate metabolism and inactivation. Drug metabolism and disposition: the biological fate of chemicals 20050601
Simultaneous quantitative assay of atazanavir and 6 other HIV protease inhibitors by isocratic reversed-phase liquid chromatography in human plasma. Therapeutic drug monitoring 20050601
A long-term survival case of small cell lung cancer in an HIV-infected patient. Japanese journal of clinical oncology 20050601
Prediction of genotoxicity of chemical compounds by statistical learning methods. Chemical research in toxicology 20050601
Comparison of efavirenz and nevirapine in HIV-infected patients (NEEF Cohort). International journal of STD & AIDS 20050601
Pregnancy category change for efavirenz. AIDS patient care and STDs 20050601
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20050601
Intracellular measurements of anti-HIV drugs indinavir, amprenavir, saquinavir, ritonavir, nelfinavir, lopinavir, atazanavir, efavirenz and nevirapine in peripheral blood mononuclear cells by liquid chromatography coupled to tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050525
The molecular basis of resilience to the effect of the Lys103Asn mutation in non-nucleoside HIV-1 reverse transcriptase inhibitors studied by targeted molecular dynamics simulations. Journal of the American Chemical Society 20050525
Quantum study of mutational effect in binding of efavirenz to HIV-1 RT. Proteins 20050515
Influence of 516G>T polymorphisms at the gene encoding the CYP450-2B6 isoenzyme on efavirenz plasma concentrations in HIV-infected subjects. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050501
Spectrum of antiviral activity of o-(acetoxyphenyl)hept-2-ynyl sulphide (APHS). International journal of antimicrobial agents 20050501
Increased dose of lopinavir/ritonavir compensates for efavirenz-induced drug-drug interaction in HIV-1-infected children. Journal of acquired immune deficiency syndromes (1999) 20050501
Nonnucleoside reverse transcriptase inhibitor phenotypic hypersusceptibility can be demonstrated in different assays. Journal of acquired immune deficiency syndromes (1999) 20050501
Combination of candidate microbicides cellulose acetate 1,2-benzenedicarboxylate and UC781 has synergistic and complementary effects against human immunodeficiency virus type 1 infection. Antimicrobial agents and chemotherapy 20050501
The Protease Inhibitor Transfer Study (PROTRA 1): abacavir and efavirenz in combination as a substitute for a protease inhibitor in heavily pretreated HIV-1-infected patients with undetectable plasma viral load. HIV medicine 20050501
Better maintained adherence on switching from twice-daily to once-daily therapy for HIV: a 24-week randomized trial of treatment simplification using stavudine prolonged-release capsules. HIV medicine 20050501
The development of vaginal microbicides for the prevention of HIV transmission. PLoS medicine 20050501
Emerging anti-HIV drugs. Expert opinion on emerging drugs 20050501
[Efavirenz]. Revue de l'infirmiere 20050501
The N137 and P140 amino acids in the p51 and the P95 amino acid in the p66 subunit of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase are instrumental to maintain catalytic activity and to design new classes of anti-HIV-1 drugs. FEBS letters 20050425
[Efavirenz--comprehensive status of studies]. MMW Fortschritte der Medizin 20050425
[Didanosine--stability as backbone drug]. MMW Fortschritte der Medizin 20050425
Long-term neuropsychiatric disorders on efavirenz-based approaches: quality of life, psychologic issues, and adherence. Journal of acquired immune deficiency syndromes (1999) 20050415
Long-term renal safety of tenofovir disoproxil fumarate in antiretroviral-naive HIV-1-infected patients. Data from a double-blind randomized active-controlled multicentre study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050401
Predictors of residual viremia in HIV-infected patients successfully treated with efavirenz and lamivudine plus either tenofovir or stavudine. The Journal of infectious diseases 20050401
Abacavir once or twice daily combined with once-daily lamivudine and efavirenz for the treatment of antiretroviral-naive HIV-infected adults: results of the Ziagen Once Daily in Antiretroviral Combination Study. Journal of acquired immune deficiency syndromes (1999) 20050401
Simple and simultaneous determination of the hiv-protease inhibitors amprenavir, atazanavir, indinavir, lopinavir, nelfinavir, ritonavir and saquinavir plus M8 nelfinavir metabolite and the nonnucleoside reverse transcriptase inhibitors efavirenz and nevirapine in human plasma by reversed-phase liquid chromatography. Therapeutic drug monitoring 20050401
Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: results of a global collaboration. PLoS medicine 20050401
Evaluation of a low cost reverse transcriptase assay for plasma HIV-1 viral load monitoring. Current HIV research 20050401
Molecular mechanics PBSA ligand binding energy and interaction of Efavirenz derivatives with HIV-1 reverse transcriptase. Journal of enzyme inhibition and medicinal chemistry 20050401
The effect of baseline CD4 cell count and HIV-1 viral load on the efficacy and safety of nevirapine or efavirenz-based first-line HAART. AIDS (London, England) 20050325
From 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk](1,4)benzodiazepin-2(1H)-one (TIBO) to etravirine (TMC125): fifteen years of research on non-nucleoside inhibitors of HIV-1 reverse transcriptase. Journal of medicinal chemistry 20050324
In search of a novel anti-HIV drug: multidisciplinary coordination in the discovery of 4-[[4-[[4-[(1E)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile (R278474, rilpivirine). Journal of medicinal chemistry 20050324
Design, synthesis, and SAR of a novel pyrazinone series with non-nucleoside HIV-1 reverse transcriptase inhibitory activity. Journal of medicinal chemistry 20050324
4-Benzyl and 4-benzoyl-3-dimethylaminopyridin-2(1H)-ones: in vitro evaluation of new C-3-amino-substituted and C-5,6-alkyl-substituted analogues against clinically important HIV mutant strains. Journal of medicinal chemistry 20050324
Synthesis of novel diarylpyrimidine analogues and their antiviral activity against human immunodeficiency virus type 1. Journal of medicinal chemistry 20050324
Rapid viral load suppression following generic highly active antiretroviral therapy in Southern Indian HIV-infected patients. AIDS (London, England) 20050324
[Efficacy of anti-HIV treatment and drug-resistance mutations in some parts of China]. Zhonghua yi xue za zhi 20050323
Severe hepatotoxicity associated with nevirapine use in HIV-infected subjects. The Journal of infectious diseases 20050315
Simplification therapy with once-daily emtricitabine, didanosine, and efavirenz in HIV-1-infected adults with viral suppression receiving a protease inhibitor-based regimen: a randomized trial. The Journal of infectious diseases 20050315
5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family. Bioorganic & medicinal chemistry 20050315
Inhibition of phosphorolysis catalyzed by HIV-1 reverse transcriptase is responsible for the synergy found in combinations of 3'-azido-3'-deoxythymidine with nonnucleoside inhibitors. Biochemistry 20050308
An MDR1-3435 variant is associated with higher plasma nelfinavir levels and more rapid virologic response in HIV-1 infected children. AIDS (London, England) 20050304
Plasma HIV-1 RNA decline within the first two weeks of treatment is comparable for nevirapine, efavirenz, or both drugs combined and is not predictive of long-term virologic efficacy: A 2NN substudy. Journal of acquired immune deficiency syndromes (1999) 20050301
Can we get more HIV-positive tuberculosis patients on antiretroviral treatment in a rural district of Malawi? The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20050301
Adverse effects of antiretroviral therapy for HIV infection: a review of selected topics. Expert opinion on drug safety 20050301
The safety of antiretroviral drugs in pregnancy. Expert opinion on drug safety 20050301
Risk of AIDS and death at given HIV-RNA and CD4 cell count, in relation to specific antiretroviral drugs in the regimen. AIDS (London, England) 20050218
The efavirenz-induced increase in HDL-cholesterol is influenced by the multidrug resistance gene 1 C3435T polymorphism. AIDS (London, England) 20050218
Studies of non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 2: synthesis and structure-activity relationships of 2-cyano and 2-hydroxy thiazolidenebenzenesulfonamide derivatives. Bioorganic & medicinal chemistry 20050215
Influence of liver fibrosis on highly active antiretroviral therapy-associated hepatotoxicity in patients with HIV and hepatitis C virus coinfection. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050215
A randomized study comparing a three- and four-drug HAART regimen in first-line therapy (QUAD study). The Journal of antimicrobial chemotherapy 20050201
Variations of CYP3A activity induced by antiretroviral treatment in HIV-1 infected patients. European journal of clinical pharmacology 20050201
Efavirenz intoxication due to slow hepatic metabolism. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050201
An extremely different dysmetabolic profile between the two available nonnucleoside reverse transcriptase inhibitors: efavirenz and nevirapine. Journal of acquired immune deficiency syndromes (1999) 20050201
6-[1-(4-Fluorophenyl)methyl-1H-pyrrol-2-yl)]-2,4-dioxo-5-hexenoic acid ethyl ester a novel diketo acid derivative which selectively inhibits the HIV-1 viral replication in cell culture and the ribonuclease H activity in vitro. Antiviral research 20050201
Collaboration begins on combined drug. AIDS patient care and STDs 20050201
Efavirenz reclassified as FDA pregnancy category D. AIDS clinical care 20050201
[HIV-1 polymorphism and development of resistance mutations against non-nucleoside reverse transcriptase inhibitor, efavirenz]. The Japanese journal of antibiotics 20050201
Incidence and risk factors for rash in Thai patients randomized to regimens with nevirapine, efavirenz or both drugs. AIDS (London, England) 20050128
Early virological failure in treatment-naive HIV-infected adults receiving didanosine and tenofovir plus efavirenz or nevirapine. AIDS (London, England) 20050128
Efavirenz enhances the proteolytic processing of an HIV-1 pol polyprotein precursor and reverse transcriptase homodimer formation. FEBS letters 20050117
Docking and 3-D QSAR studies on indolyl aryl sulfones. Binding mode exploration at the HIV-1 reverse transcriptase non-nucleoside binding site and design of highly active N-(2-hydroxyethyl)carboxamide and N-(2-hydroxyethyl)carbohydrazide derivatives. Journal of medicinal chemistry 20050113
Detection of minority populations of HIV-1 expressing the K103N resistance mutation in patients failing nevirapine. Journal of acquired immune deficiency syndromes (1999) 20050101
Antiretroviral drug pharmacokinetics in hepatitis with hepatic dysfunction. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050101
Drug resistance mutations in the nucleotide binding pocket of human immunodeficiency virus type 1 reverse transcriptase differentially affect the phosphorolysis-dependent primer unblocking activity in the presence of stavudine and zidovudine and its inhibition by efavirenz. Antimicrobial agents and chemotherapy 20050101
Substituting abacavir for hyperlipidemia-associated protease inhibitors in HAART regimens improves fasting lipid profiles, maintains virologic suppression, and simplifies treatment. BMC infectious diseases 20050101
No influence of the P-glycoprotein polymorphisms MDR1 G2677T/A and C3435T on the virological and immunological response in treatment naïve HIV-positive patients. Annals of clinical microbiology and antimicrobials 20050101
NNRTI hypersusceptibility. The AIDS reader 20050101
Changes in lipids over twelve months after initiating protease inhibitor therapy among persons treated for HIV/AIDS. Lipids in health and disease 20050101
Molecular strategies to inhibit HIV-1 replication. Retrovirology 20050101
Top stories of 2004. ACTG 5095: efavirenz beats AZT + 3TC + abacavir. AIDS clinical care 20050101
Top stories of 2004. Nevirapine and efavirenz: similar efficacy, different toxicities, and better separately than combined. AIDS clinical care 20050101
New York City HIV superbug: fear or fear not? Retrovirology 20050101
Nevirapine and efavirenz pharmacokinetics and covariate analysis in the 2NN study. Antiviral therapy 20050101
Early virological failure with a combination of tenofovir, didanosine and efavirenz. Antiviral therapy 20050101
[Cost-effectiveness analysis of tenofovir versus zidovudine in combination therapy with efavirenz and lamivudine for the treatment of HIV in naive patients]. Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20050101
Should non-nucleoside reverse transcriptase inhibitors be combined? Drugs in R&D 20050101
Insomnia in HIV infection: a systematic review of prevalence, correlates, and management. Psychosomatic medicine 20050101
Abacavir, efavirenz, didanosine, with or without hydroxyurea, in HIV-infected adults failing initial nucleoside/protease inhibitor-containing regimens. BMC infectious diseases 20050101
The non-nukes. Sustiva. Viramune. The two major players. Positively aware : the monthly journal of the Test Positive Aware Network 20050101
Influence of CYP2B6 polymorphism on plasma and intracellular concentrations and toxicity of efavirenz and nevirapine in HIV-infected patients. Pharmacogenetics and genomics 20050101
Rare one and two amino acid inserts adjacent to codon 103 of the HIV-1 reverse transcriptase (RT) affect susceptibility to non-nucleoside RT inhibitors. Antiviral therapy 20050101
Pharmacokinetics and pharmacodynamics of low dose mycophenolate mofetil in HIV-infected patients treated with abacavir, efavirenz and nelfinavir. Clinical pharmacokinetics 20050101
The two-year impact of first generation protease inhibitor based antiretroviral therapy (PI-ART) on health-related quality of life. Health and quality of life outcomes 20050101
Recurrence of post-traumatic stress disorder and antiretrovirals. Scandinavian journal of infectious diseases 20050101
Breakthrough Candida infections in patients receiving voriconazole. The Annals of pharmacotherapy 20050101
Enantiopure drug synthesis: from methyldopa to imipenem to efavirenz. Chirality 20050101
[Efavirenz and nevirapine plasma levels in HIV-infected patients with hemophilia]. Enfermedades infecciosas y microbiologia clinica 20050101
Virologic and immunologic response to a boosted double-protease inhibitor-based therapy in highly pretreated HIV-1-infected patients. HIV clinical trials 20050101
Severe CNS side-effect and persistent high efavirenz plasma levels in a patient with HIV/HCV coinfection and liver cirrhosis. Scandinavian journal of infectious diseases 20050101
Incidence and risk factors for liver enzyme elevation during highly active antiretroviral therapy in HIV-HCV co-infected patients: results from the Italian EPOKA-MASTER Cohort. BMC infectious diseases 20050101
Population pharmacokinetics of efavirenz in an unselected cohort of HIV-1-infected individuals. Clinical pharmacokinetics 20050101
Are adverse events of nevirapine and efavirenz related to plasma concentrations? Antiviral therapy 20050101
Early virological failure after tenofovir + didanosine + efavirenz combination in HIV-positive patients upon starting antiretroviral therapy. Antiviral therapy 20050101
Reverse transcriptase inhibitors alter uncoupling protein-1 and mitochondrial biogenesis in brown adipocytes. Antiviral therapy 20050101
Drug-drug interactions and the pharmacotherapy of HIV infection. Topics in HIV medicine : a publication of the International AIDS Society, USA 20050101
Safety and tolerability of nevirapine-based antiretroviral therapy in HIV-infected patients receiving fluconazole for cryptococcal prophylaxis: a retrospective cohort study. BMC infectious diseases 20050101
Lipid profiles for antiretroviral-naive patients starting PI- and NNRTI-based therapy in the Swiss HIV cohort study. Antiviral therapy 20050101
Low density lipoprotein apolipoprotein B metabolism in treatment-naive HIV patients and patients on antiretroviral therapy. Antiviral therapy 20050101
Efavirenz induces depressive-like behaviour, increased stress response and changes in the immune response in rats. Neuroimmunomodulation 20050101
Will pharmacogenomic discoveries improve HIV therapeutics? Topics in HIV medicine : a publication of the International AIDS Society, USA 20050101
Clinical pharmacokinetics and summary of efficacy and tolerability of atazanavir. Clinical pharmacokinetics 20050101
Mycobacterial immune reconstitution inflammatory syndrome in HIV-1 infection after antiretroviral therapy is associated with deregulated specific T-cell responses: beneficial effect of IL-2 and GM-CSF immunotherapy. Journal of immune based therapies and vaccines 20050101
The nonnucleoside reverse transcriptase inhibitors efavirenz and nevirapine in the treatment of HIV. HIV clinical trials 20050101
Quantification of antiretroviral drugs in dried blood spot samples by means of liquid chromatography/tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20050101
Comparison of neuropsychiatric side effects in an observational cohort of efavirenz- and protease inhibitor-treated patients. HIV clinical trials 20050101
Viral load responses to HAART is an independent predictor of a new AIDS event in late stage HIV infected patients: prospective cohort study. Journal of translational medicine 20050101
Cerebrospinal fluid HIV infection and pleocytosis: relation to systemic infection and antiretroviral treatment. BMC infectious diseases 20050101
First-line antiretroviral therapy in Africa--how evidence-base are our recommendations? AIDS reviews 20050101
Are specific antiretrovirals associated with an increased risk of discontinuation due to toxicities or patient/physician choice in patients with hepatitis C virus coinfection? Antiviral therapy 20050101
Simplification therapy with once-daily didanosine, tenofovir and efavirenz in HIV-1-infected adults with viral suppression receiving a more complex antiretroviral regimen: final results of the EFADITE trial. Antiviral therapy 20050101
Do non-nucleoside reverse transcriptase inhibitors contribute to lipodystrophy? Drug safety 20050101
Scutellaria baicalensis decreases ritonavir-induced nausea. AIDS research and therapy 20050101
TMC125: new results, large phase III trial begins. AIDS treatment news 20050101
[Non-nucleoside inhibitors of reverse transcriptase in therapy of HIV-infection]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20050101
Role of the inhibitory quotient in HIV therapy. Antiviral therapy 20050101
Improvement in dyslipidaemia after switching stavudine to tenofovir and replacing protease inhibitors with efavirenz in HIV-infected children. Antiviral therapy 20050101
Prospective, open-label comparative study of liver toxicity in an unselected population of HIV-infected patients treated for the first time with efavirenz or nevirapine. HIV clinical trials 20050101
Higher virological effectiveness of NNRTI-based antiretroviral regimens containing nevirapine or efavirenz compared to a triple NRTI regimen as initial therapy in HIV-1-infected adults. HIV clinical trials 20050101
Simplicity and efficacy of a once-daily antiretroviral regimen with didanosine, lamivudine, and efavirenz in naïve patients: the VESD study. HIV clinical trials 20050101
Antiretroviral Therapy in the Real World : Population-Based Pharmacoeconomic Analysis of Administration of Anti-HIV Regimens to 990 Patients. Clinical drug investigation 20050101
[Efficacy and tolerance of non nucleosidic reverse transcriptase inhibitors containing tritherapy in HIV-1 infection]. Dakar medical 20050101
Substitutions in the Reverse Transcriptase and Protease Genes of HIV-1 Subtype B in Untreated Individuals and Patients Treated With Antiretroviral Drugs. Journal of the International AIDS Society 20050101
The HIV-1 Non-subtype B Workgroup: An International Collaboration for the Collection and Analysis of HIV-1 Non-subtype B Data. Journal of the International AIDS Society 20050101
Triple-nucleoside analog antiretroviral therapy: is there still a role in clinical practice? A review. Journal of the International AIDS Society 20050101
Genetic barriers to resistance and impact on clinical response. Journal of the International AIDS Society 20050101
Simultaneous determination of the antiretroviral agents: amprenavir, lopinavir, ritonavir, saquinavir and efavirenz in human peripheral blood mononuclear cells by high-performance liquid chromatography-mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225
Determination of atazanavir and other antiretroviral drugs (indinavir, amprenavir, nelfinavir and its active metabolite M8, saquinavir, ritonavir, lopinavir, nevirapine and efavirenz) plasma levels by high performance liquid chromatography with UV detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225
Phenotypic susceptibility to nonnucleoside inhibitors of virion-associated reverse transcriptase from different HIV types and groups. Journal of acquired immune deficiency syndromes (1999) 20041215
Pharmacogenetics of efavirenz and central nervous system side effects: an Adult AIDS Clinical Trials Group study. AIDS (London, England) 20041203
Flexible docking of pyridinone derivatives into the non-nucleoside inhibitor binding site of HIV-1 reverse transcriptase. Bioorganic & medicinal chemistry 20041201
Studies of nonnucleoside HIV-1 reverse transcriptase inhibitors. Part 1: Design and synthesis of thiazolidenebenzenesulfonamides. Bioorganic & medicinal chemistry 20041201
Mutations associated with hypersusceptibility...and with good adherence. The Journal of infectious diseases 20041201
TMC125, a novel next-generation nonnucleoside reverse transcriptase inhibitor active against nonnucleoside reverse transcriptase inhibitor-resistant human immunodeficiency virus type 1. Antimicrobial agents and chemotherapy 20041201
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The first case of efavirenz-induced photosensitivity in a Japanese patient with HIV infection. Internal medicine (Tokyo, Japan) 20040701
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A proof-of-concept study of short-cycle intermittent antiretroviral therapy with a once-daily regimen of didanosine, lamivudine, and efavirenz for the treatment of chronic HIV infection. The Journal of infectious diseases 20040601
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HIV/AIDS news: comparable anti-HIV antiviral efficacy of Viramune and Efavirenz--the Lancet publishes first large-scale comparison study. Infection 20040601
Evaluation of the virological and metabolic effects of switching protease inhibitor combination antiretroviral therapy to nevirapine-based therapy for the treatment of HIV infection. AIDS research and human retroviruses 20040601
Efficacy and safety of Efavirenz in HIV patients on Rifampin for tuberculosis. The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20040601
Effect of stereo and regiochemistry towards wild and multidrug resistant HIV-1 virus: viral potency of chiral PETT derivatives. Biochemical pharmacology 20040515
Roles of conformational and positional adaptability in structure-based design of TMC125-R165335 (etravirine) and related non-nucleoside reverse transcriptase inhibitors that are highly potent and effective against wild-type and drug-resistant HIV-1 variants. Journal of medicinal chemistry 20040506
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Genes, ethnicity, and efavirenz response: clinical pharmacology update from the 11th CROI. The Hopkins HIV report : a bimonthly newsletter for healthcare providers 20040501
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[Protease inhibitor sparing standard. Once daily efavirenz continues to be effective]. MMW Fortschritte der Medizin 20040426
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Structural and energetic analyses of the effects of the K103N mutation of HIV-1 reverse transcriptase on efavirenz analogues. Journal of medicinal chemistry 20040422
Antiretroviral therapy for previously untreated HIV-1-infected adults: 2NN, or just one? Lancet (London, England) 20040417
Comparison of first-line antiretroviral therapy with regimens including nevirapine, efavirenz, or both drugs, plus stavudine and lamivudine: a randomised open-label trial, the 2NN Study. Lancet (London, England) 20040417
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Pharmacokinetics and safety of GW433908 and ritonavir, with and without efavirenz, in healthy volunteers. AIDS (London, England) 20040409
Genetic variation at NNRTI resistance-associated positions in patients infected with HIV-1 subtype C. AIDS (London, England) 20040409
Tenofovir-related nephrotoxicity in HIV-infected patients. AIDS (London, England) 20040409
Therapeutic drug monitoring of lopinavir/ritonavir given alone or with a non-nucleoside reverse transcriptase inhibitor. British journal of clinical pharmacology 20040401
Clinical, virologic, and immunologic response to efavirenz-or protease inhibitor-based highly active antiretroviral therapy in a cohort of antiretroviral-naive patients with advanced HIV infection (EfaVIP 2 study). Journal of acquired immune deficiency syndromes (1999) 20040401
Safety and efficacy of a NRTI-sparing HAART regimen of efavirenz and lopinavir/ritonavir in HIV-1-infected children. Antiviral therapy 20040401
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Efavirenz induces a striking and generalized increase of HDL-cholesterol in HIV-infected patients. AIDS (London, England) 20040326
Lipid profiles in HIV-infected patients receiving combination antiretroviral therapy: are different antiretroviral drugs associated with different lipid profiles? The Journal of infectious diseases 20040315
Merck broke AIDS drug price promise, says MSF. Lancet (London, England) 20040313
Synthesis of 6-arylvinyl analogues of the HIV drugs SJ-3366 and Emivirine. Bioorganic & medicinal chemistry 20040301
Pharmacokinetics of emtricitabine, didanosine and efavirenz administered once-daily for the treatment of HIV-infected adults (pharmacokinetic substudy of the ANRS 091 trial). HIV medicine 20040301
Nevirapine- versus efavirenz-based highly active antiretroviral therapy regimens in antiretroviral-naïve patients with advanced HIV infection. HIV medicine 20040301
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Virological and immunological outcomes in HIV-1-infected Chinese patients treated with a combination of Efavirenz and Indinavir for 48 weeks. Chinese medical journal 20040301
Chemokine mRNA levels in mononucleated cells of HIV-infected patients before and after initiation of PI- versus NNRTI-containing HAART. Antiviral research 20040301
Novel benzophenones as non-nucleoside reverse transcriptase inhibitors of HIV-1. Journal of medicinal chemistry 20040226
Defining a molecular mechanism of synergy between nucleoside and nonnucleoside AIDS drugs. The Journal of biological chemistry 20040220
Pharmacokinetics of indinavir/ritonavir (800/100 mg twice a day) combined with efavirenz in HIV-infected patients. AIDS (London, England) 20040220
Dose escalation or immediate full dose when switching from efavirenz to nevirapine-based highly active antiretroviral therapy in HIV-1-infected individuals? AIDS (London, England) 20040220
Computer-aided design, synthesis, and anti-HIV-1 activity in vitro of 2-alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as novel potent non-nucleoside reverse transcriptase inhibitors, also active against the Y181C variant. Journal of medicinal chemistry 20040212
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Analyzing sleep abnormalities in HIV-infected patients treated with Efavirenz. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040201
Newer treatments for HIV in children. Current opinion in pediatrics 20040201
Experience with efavirenz in end-stage renal disease. International journal of STD & AIDS 20040201
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Monitoring of didanosine and stavudine intracellular trisphosphorylated anabolite concentrations in HIV-infected patients. AIDS (London, England) 20040123
Stereoselective metabolism of methadone N-demethylation by cytochrome P4502B6 and 2C19. Chirality 20040101
Emtricitabine: a new nucleoside analogue for once-daily antiretroviral therapy. Expert opinion on investigational drugs 20040101
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Susceptibility of feline immunodeficiency virus/human immunodeficiency virus type 1 reverse transcriptase chimeras to non-nucleoside RT inhibitors. Molecular pharmacology 20040101
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A case-control study of gynecomastia in HIV-1-infected patients receiving HAART. The AIDS reader 20040101
Editorial comment: unraveling the cause of HIV-related gynecomastia. The AIDS reader 20040101
Safe substitution for efavirenz. AIDS patient care and STDs 20040101
Higher Sustiva levels seen in some African-Americans. GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies 20040101
Efavirenz-associated gynecomastia: report of five cases and review of the literature. The breast journal 20040101
Anti-HIV drug distribution to the central nervous system. Current pharmaceutical design 20040101
Current status of the non-nucleoside reverse transcriptase inhibitors of human immunodeficiency virus type 1. Current topics in medicinal chemistry 20040101
Emtricitabine/tenofovir disoproxil fumarate. Drugs in R&D 20040101
Anti-retrovirals and immunosuppressive drug interactions in a HIV-positive patient after liver transplantation. Hepato-gastroenterology 20040101
Recent advances in the development of next generation non-nucleoside reverse transcriptase inhibitors. Current topics in medicinal chemistry 20040101
Life after Sustiva. Survival news (Atlanta, Ga.) 20040101
Efficacy of quality criteria to identify potentially harmful information: a cross-sectional survey of complementary and alternative medicine web sites. Journal of medical Internet research 20040101
Cortisol serum levels and their relationship to certain antiretroviral drugs. Scandinavian journal of infectious diseases 20040101
Emtricitabine/tenofovir disoproxil fumarate. Drugs 20040101
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Practical guidelines to interpret plasma concentrations of antiretroviral drugs. Clinical pharmacokinetics 20040101
Proteomics computational analyses suggest that the carboxyl terminal glycoproteins of Bunyaviruses are class II viral fusion protein (beta-penetrenes). Theoretical biology & medical modelling 20040101
Antiretrovirals, Part II: focus on non-protease inhibitor antiretrovirals (NRTIs, NNRTIs, and fusion inhibitors). Psychosomatics 20040101
Spectrum of clinical disease in a series of 135 hospitalised HIV-infected patients from north India. BMC infectious diseases 20040101
Pharmacokinetics of antiretrovirals administered to HIV-infected children via gastrostomy tube. HIV clinical trials 20040101
Pharmacokinetics of antiretrovirals in pregnant women. Clinical pharmacokinetics 20040101
The unmasking of Pneumocystis jiroveci pneumonia during reversal of immunosuppression: case reports and literature review. BMC infectious diseases 20040101
FDA issues labeling changes for efavirenz. AIDS reviews 20040101
Behind 'AIDS breakthrough' headlines, December 2004: important research, not so new. AIDS treatment news 20040101
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Substitution for protease inhibitors in HIV therapy. The New England journal of medicine 20031218
3-iodo-4-phenoxypyridinones (IOPY's), a new family of highly potent non-nucleoside inhibitors of HIV-1 reverse transcriptase. Bioorganic & medicinal chemistry letters 20031215
Oxidant stress is increased during treatment of human immunodeficiency virus infection. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20031215
Comparison of sequential three-drug regimens as initial therapy for HIV-1 infection. The New England journal of medicine 20031211
Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. The New England journal of medicine 20031211
No influence of the P-glycoprotein genotype (MDR1 C3435T) on plasma levels of lopinavir and efavirenz during antiretroviral treatment. European journal of medical research 20031209
Provider bias in the selection of non-nucleoside reverse transcriptase inhibitor and protease inhibitor-based highly active antiretroviral therapy and HIV treatment outcomes in observational studies. AIDS (London, England) 20031205
An open-label assessment of TMC 125--a new, next-generation NNRTI, for 7 days in HIV-1 infected individuals with NNRTI resistance. AIDS (London, England) 20031205
Therapeutic drug monitoring of the HIV/AIDS drugs abacavir, zidovudine, efavirenz, nevirapine, indinavir, lopinavir, and nelfinavir. Pharmacology 20031201
Nevirapine plus efavirenz plus didanosine: a simple, safe, and effective once-daily regimen for patients with HIV infection. Journal of the National Medical Association 20031201
A randomized trial of nelfinavir and abacavir in combination with efavirenz and adefovir dipivoxil in HIV-1-infected persons with virological failure receiving indinavir. Antiviral therapy 20031201
The continuing evolution of HIV therapy. The AIDS reader 20031201
Meta-analysis of randomized controlled trials of simplified versus continued protease inhibitor-based antiretroviral therapy in HIV-1-infected patients. AIDS (London, England) 20031121
Efavirenz-containing highly active antiretroviral therapy in an HIV-infected patient with myasthenia gravis. AIDS (London, England) 20031121
Evaluation of cutpoints for phenotypic hypersusceptibility to efavirenz. AIDS (London, England) 20031107
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Triple combinations regimens for HIV. The Lancet. Infectious diseases 20031101
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Atazanavir sulphate. Nature reviews. Drug discovery 20031101
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Failures of 1 week on, 1 week off antiretroviral therapies in a randomized trial. AIDS (London, England) 20031017
Activity predictions for efavirenz analogues with the K103N mutant of HIV reverse transcriptase. Bioorganic & medicinal chemistry letters 20031006
In silico structure-based design of a potent, mutation resilient, small peptide inhibitor of HIV-1 reverse transcriptase. Journal of biomolecular structure & dynamics 20031001
Pharmacokinetics of indinavir/ritonavir (800/100 mg) in combination with efavirenz (600 mg) in HIV-1-infected subjects. Journal of acquired immune deficiency syndromes (1999) 20031001
Issues in antiretroviral toxicity. The AIDS reader 20031001
Once-daily therapy: less is more. International journal of STD & AIDS 20031001
Efavirenz: enhancing the gold standard. International journal of STD & AIDS 20031001
Releasing the true power of protease inhibitors. International journal of STD & AIDS 20031001
Predictors of the virological response to a change in the antiretroviral treatment regimen in HIV-1-infected patients enrolled in a randomized trial comparing genotyping, phenotyping and standard of care (Narval trial, ANRS 088). Antiviral therapy 20031001
Atazanavir: improving the HIV protease inhibitor class. Expert review of anti-infective therapy 20031001
Evaluation of a didanosin-containing regimen including genotypic resistance testing: an open-label, multicenter study. European journal of medical research 20030929
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A randomized trial of 2 different 4-drug antiretroviral regimens versus a 3-drug regimen, in advanced human immunodeficiency virus disease. The Journal of infectious diseases 20030901
Inhibition of human immunodeficiency virus by a new class of pyridine oxide derivatives. Antimicrobial agents and chemotherapy 20030901
Factors associated with maintenance of long-term plasma human immunodeficiency virus RNA suppression. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030901
[Use of antiretroviral drugs in HIV infected children in a tropical area: a real benefit]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20030901
Perspectives on HAART: switch maintenance therapy. International journal of STD & AIDS 20030901
A comprehensive hepatic safety analysis of nevirapine in different populations of HIV infected patients. Journal of acquired immune deficiency syndromes (1999) 20030901
Efficacy and durability of nevirapine in antiretroviral drug näive patients. Journal of acquired immune deficiency syndromes (1999) 20030901
Tipranavir: a protease inhibitor from a new class with distinct antiviral activity. Journal of acquired immune deficiency syndromes (1999) 20030901
Drug resistance profiles of recombinant reverse transcriptases from human immunodeficiency virus type 1 subtypes A/E, B, and C. AIDS research and human retroviruses 20030901
Protein binding in antiretroviral therapies. AIDS research and human retroviruses 20030901
Meeting notes from the 2nd International AIDS Society Conference on HIV Pathogenesis and Treatment. Trizivir vs. efavirenz: results from ACTG 5095. AIDS clinical care 20030901
The effects of protease inhibitors and nonnucleoside reverse transcriptase inhibitors on p-glycoprotein expression in peripheral blood mononuclear cells in vitro. Journal of acquired immune deficiency syndromes (1999) 20030815
Evaluation of a ristocetin bonded stationary phase for subcritical fluid chromatography of enantiomers. Chirality 20030801
Hyperlipidaemia in patients with HIV-1 infection receiving highly active antiretroviral therapy: epidemiology, pathogenesis, clinical course and management. International journal of antimicrobial agents 20030801
The effect of NNRTIs on HIV reverse transcriptase dimerization. Current opinion in investigational drugs (London, England : 2000) 20030801
A controlled Phase II trial assessing three doses of enfuvirtide (T-20) in combination with abacavir, amprenavir, ritonavir and efavirenz in non-nucleoside reverse transcriptase inhibitor-naive HIV-infected adults. Antiviral therapy 20030801
Low frequency of the V106M mutation among HIV-1 subtype C-infected pregnant women exposed to nevirapine. AIDS (London, England) 20030725
A manic episode associated with efavirenz therapy for HIV infection. AIDS (London, England) 20030725
Simple and rapid method for the simultaneous determination of the non-nucleoside reverse transcriptase inhibitors efavirenz and nevirapine in human plasma using liquid chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030725
Alternation of antiretroviral drug regimens for HIV infection. A randomized, controlled trial. Annals of internal medicine 20030715
Use of HIV-1 reverse transcriptase recovered from human plasma for phenotypic drug susceptibility testing. AIDS (London, England) 20030704
The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity. The Journal of pharmacology and experimental therapeutics 20030701
Outcome of 2 simplification strategies for the treatment of human immunodeficiency virus type 1 infection. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030701
Photodermatitis in a patient with HIV infection. Journal of the American Academy of Dermatology 20030701
Recurrence of post-traumatic stress disorder symptoms after initiation of antiretrovirals including efavirenz: a report of two cases. HIV medicine 20030701
Experience with efavirenz in end-stage renal disease. International journal of STD & AIDS 20030701
NNRTI choice: has 2NN changed our practice? The AIDS reader 20030701
Synthesis of novel MKC-442 analogues with potent activities against HIV-1. Archiv der Pharmazie 20030701
Variable prediction of antiretroviral treatment outcome by different systems for interpreting genotypic human immunodeficiency virus type 1 drug resistance. The Journal of infectious diseases 20030615
Hypersusceptibility to non-nucleoside reverse transcriptase inhibitors in HIV-1. AIDS (London, England) 20030613
Novel indolyl aryl sulfones active against HIV-1 carrying NNRTI resistance mutations: synthesis and SAR studies. Journal of medicinal chemistry 20030605
Reverse phase high-performance liquid chromatography method for the analysis of amprenavir, efavirenz, indinavir, lopinavir, nelfinavir and its active metabolite (M8), ritonavir, and saquinavir in heparinized human plasma. Therapeutic drug monitoring 20030601
A simple HPLC method for simultaneous determination of lopinavir, ritonavir and efavirenz. Chemical & pharmaceutical bulletin 20030601
Use of SAM2 biotin capture membrane in microarrayed compound screening (muARCS) format for nucleic acid polymerization assays. Journal of biomolecular screening 20030601
Nucleoside-free regimen tested. AIDS patient care and STDs 20030601
Comparison of nine resistance interpretation systems for HIV-1 genotyping. Antiviral therapy 20030601
Protease inhibitor-sparing regimens: new evidence strengthens position. Journal of acquired immune deficiency syndromes (1999) 20030601
NIAID comments on AACTG Study A5095. IAPAC monthly 20030601
Sensitive and specific determination of eight antiretroviral agents in plasma by high-performance liquid chromatography-mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030525
Validation of a model for the complex of HIV-1 reverse transcriptase with nonnucleoside inhibitor TMC125. Journal of the American Chemical Society 20030521
[Assessment of adherence to antiretroviral: role of determination of plasma levels of non nucleosides anologues]. Medicina clinica 20030517
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Once-a-day highly active antiretroviral therapy in treatment-naive HIV-1-infected adults in Senegal. AIDS (London, England) 20030502
Adherence to highly active antiretroviral therapy is better in patients receiving non-nucleoside reverse transcriptase inhibitor-containing regimens than in those receiving protease inhibitor-containing regimens. AIDS (London, England) 20030502
APHS can act synergically with clinically available HIV-1 reverse transcriptase and protease inhibitors and is active against several drug-resistant HIV-1 strains in vitro. The Journal of antimicrobial chemotherapy 20030501
Once-a-day highly active antiretroviral therapy: a systematic review. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030501
Efavirenz-based regimen as treatment of advanced AIDS with cryptococcal meningitis. Journal of acquired immune deficiency syndromes (1999) 20030501
Toxicity of non-nucleoside analogue reverse transcriptase inhibitors. Seminars in liver disease 20030501
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[Highly effective drug without modifying the lipid profile. Atazanavir, the protease inhibitor for 'once daily' administration]. MMW Fortschritte der Medizin 20030428
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Efavirenz-induced catatonia. AIDS (London, England) 20020906
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Simultaneous quantitative assay of six HIV protease inhibitors, one metabolite, and two non-nucleoside reverse transcriptase inhibitors in human plasma by isocratic reversed-phase liquid chromatography. Therapeutic drug monitoring 20020801
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HIV and refractory anemia with excess blasts (RAEB). American journal of hematology 20020801
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Female sex but not ethnicity is a strong predictor of non-nucleoside reverse transcriptase inhibitor-induced rash. AIDS (London, England) 20020726
Efavirenz plasma levels for the prediction of treatment failure in heavily pretreated HIV-1 infected patients. European journal of medical research 20020724
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Prediction of activity for nonnucleoside inhibitors with HIV-1 reverse transcriptase based on Monte Carlo simulations. Journal of medicinal chemistry 20020704
Long-term metabolic consequences of switching from protease inhibitors to efavirenz in therapy for human immunodeficiency virus-infected patients with lipoatrophy. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020701
Genetic divergence of human immunodeficiency virus type 1 Ethiopian clade C reverse transcriptase (RT) and rapid development of resistance against nonnucleoside inhibitors of RT. Antimicrobial agents and chemotherapy 20020701
Central nervous system adverse effects with efavirenz: case report and review. Pharmacotherapy 20020701
Hepatic but not intestinal CYP3A4 displays dose-dependent induction by efavirenz in humans. Clinical pharmacology and therapeutics 20020701
Differential modulation of P-glycoprotein expression and activity by non-nucleoside HIV-1 reverse transcriptase inhibitors in cell culture. Pharmaceutical research 20020701
Efavirenz liquid formulation in human immunodeficiency virus-infected children. The Pediatric infectious disease journal 20020701
Potency of nonnucleoside reverse transcriptase inhibitors (NNRTIs) used in combination with other human immunodeficiency virus NNRTIs, NRTIs, or protease inhibitors. Antimicrobial agents and chemotherapy 20020601
High-performance liquid chromatographic method for the simultaneous determination of the six HIV-protease inhibitors and two non-nucleoside reverse transcriptase inhibitors in human plasma. Therapeutic drug monitoring 20020601
Efavirenz-associated QT prolongation and Torsade de Pointes arrhythmia. The Annals of pharmacotherapy 20020601
Determination of efavirenz, a selective non-nucleoside reverse transcriptase inhibitor, in human plasma using HPLC with post-column photochemical derivatization and fluorescence detection. Journal of pharmaceutical and biomedical analysis 20020601
NNRTIs compared in switch group. AIDS patient care and STDs 20020601
Gateways to Clinical Trials. June 2002. Methods and findings in experimental and clinical pharmacology 20020601
Normalization of liver enzymes in an HIV-hepatitis C virus-co-infected patient after potent antiretroviral therapy. AIDS (London, England) 20020524
Persistence of human immunodeficiency virus (HIV) type 1 DNA in peripheral blood despite prolonged suppression of plasma HIV-1 RNA in children. The Journal of infectious diseases 20020515
Efficacy and safety of abacavir plus efavirenz as a salvage regimen in HIV-infected individuals after 48 weeks. AIDS (London, England) 20020503
A prospective comparison of the two main indications of efavirenz in 2001 highly active antiretroviral therapy (HAART) regimens: first-line versus salvage use. The Journal of antimicrobial chemotherapy 20020501
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Virologic and immunologic response to regimens containing nevirapine or efavirenz in combination with 2 nucleoside analogues in the Italian Cohort Naive Antiretrovirals (I.Co.N.A.) study. The Journal of infectious diseases 20020415
Investigation of critical factors for the resolution of SR695, a key impurity, from efavirenz in the reversed-phase assay of efavirenz dosage forms. Journal of pharmaceutical and biomedical analysis 20020401
Simultaneous determination of the six HIV protease inhibitors (amprenavir, indinavir, lopinavir, nelfinavir, ritonavir, and saquinavir) plus M8 nelfinavir metabolite and the nonnucleoside reverse transcription inhibitor efavirenz in human plasma by solid-phase extraction and column liquid chromatography. Therapeutic drug monitoring 20020401
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Therapeutic effects of nonnucleoside reverse transcriptase inhibitors on the central nervous system in HIV-1-infected patients. Journal of acquired immune deficiency syndromes (1999) 20020401
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Kinetics and mechanism of hydrolysis of efavirenz. Pharmaceutical research 20020401
Undefined duration of opiate withdrawal induced by efavirenz in drug users with HIV infection and undergoing chronic methadone treatment. AIDS research and human retroviruses 20020320
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Management of a patient with HIV infection-induced anemia and thrombocytopenia who presented with thrombotic thrombocytopenic purpura. American journal of hematology 20020301
Efavirenz-induced skin eruption and successful desensitization. The Annals of pharmacotherapy 20020301
Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant. European journal of biochemistry 20020301
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HIV-1 genotype and phenotype correlate with virological response to abacavir, amprenavir and efavirenz in treatment-experienced patients. AIDS (London, England) 20020215
Probable interaction between efavirenz and cyclosporine. AIDS (London, England) 20020215
Gynaecomastia without lipodystrophy in HIV-1-seropositive patients on efavirenz: an alternative hypothesis. AIDS (London, England) 20020215
Periconceptional exposure to efavirenz and neural tube defects. Archives of internal medicine 20020211
Efavirenz-induced leukocytoclastic vasculitis. Archives of internal medicine 20020211
Antimicrobial and anti-lipase activity of quercetin and its C2-C16 3-O-acyl-esters. Bioorganic & medicinal chemistry 20020201
Role of sequencing in therapy selection. Journal of acquired immune deficiency syndromes (1999) 20020201
Pharmacokinetics of methadone in HIV-positive patients receiving the non-nucleoside reverse transcriptase efavirenz. British journal of clinical pharmacology 20020201
Nevirapine + efavirenz based salvage therapy in heavily pretreated HIV infected patients. Sexually transmitted infections 20020201
Immune reconstitution eosinophilia due to schistosomiasis. Sexually transmitted infections 20020201
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Swiss study switching to efavirenz. TreatmentUpdate 20020201
Efavirenz helps get rid of Kaposi's sarcoma (KS). TreatmentUpdate 20020201
Birth defect in baby born to efavirenz-user. TreatmentUpdate 20020201
Comparing liver toxicity between efavirenz and nevirapine. TreatmentUpdate 20020201
Effect of antiretroviral combination therapies including efavirenz in heavily pretreated HIV-infected children. European journal of medical research 20020129
Myelomeningocele in a child with intrauterine exposure to efavirenz. AIDS (London, England) 20020125
Complete remission of AIDS/Kaposi's sarcoma after treatment with a combination of two nucleoside reverse transcriptase inhibitors and one non-nucleoside reverse transcriptase inhibitor. AIDS (London, England) 20020125
Evidence of immune reconstitution in antiretroviral drug-experienced patients with advanced HIV disease. AIDS research and human retroviruses 20020120
Association between efavirenz and selected psychiatric and neurological conditions. The Journal of infectious diseases 20020115
Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study. Lancet (London, England) 20020105
Virological suppression at 6 months is related to choice of initial regimen in antiretroviral-naive patients: a cohort study. AIDS (London, England) 20020104
Primary infection with a lamivudine-resistant hepatitis B virus. AIDS (London, England) 20020104
Pilot study of the effects of intermittent interleukin-2 on human immunodeficiency virus (HIV)-specific immune responses in patients treated during recently acquired HIV infection. The Journal of infectious diseases 20020101
Dioxolane guanosine, the active form of the prodrug diaminopurine dioxolane, is a potent inhibitor of drug-resistant HIV-1 isolates from patients for whom standard nucleoside therapy fails. Journal of acquired immune deficiency syndromes (1999) 20020101
Brief report: two-year outcome of a multidrug regimen in patients who did not respond to a protease inhibitor regimen. Journal of acquired immune deficiency syndromes (1999) 20020101
Hepatotoxicity associated with nevirapine or efavirenz-containing antiretroviral therapy: role of hepatitis C and B infections. Hepatology (Baltimore, Md.) 20020101
Antiretroviral rounds. A very discordant response. AIDS clinical care 20020101
The influence of efavirenz on the pharmacokinetics of a twice-daily combination of indinavir and low-dose ritonavir in healthy volunteers. Clinical pharmacology and therapeutics 20020101
Efavirenz and retinal toxicity. Eye (London, England) 20020101
Two protease inhibitor switch studies show longer virologic response in patients switching to a regimen containing Sustiva. The Journal of the Association of Nurses in AIDS Care : JANAC 20020101
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Genotype resistance profiles in patients failing an NNRTI-containing regimen, and modifications after stopping NNRTI therapy. Journal of clinical laboratory analysis 20020101
SENC (Spanish efavirenz vs. nevirapine comparison) trial: a randomized, open-label study in HIV-infected naive individuals. HIV clinical trials 20020101
Pharmacokinetic interactions between efavirenz and rifampicin in HIV-infected patients with tuberculosis. Clinical pharmacokinetics 20020101
Clinical implications of CNS penetration of antiretroviral drugs. CNS drugs 20020101
[Plasmatic dosage of antiretroviral drugs by high performance liquid chromathography ]. Therapie 20020101
The HYDILE trial: efficacy and tolerance of a quadruple combination of reverse transcriptase inhibitors versus the same regimen plus hydroxyurea or hydroxyurea and interleukin-2 in HIV-infected patients failing protease inhibitor-based combinations. HIV clinical trials 20020101
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Comparison of nevirapine- and efavirenz-containing antiretroviral regimens in antiretroviral-naïve patients: a cohort study. HIV clinical trials 20020101
Antiretroviral pharmacokinetics in the paediatric population: a review. Clinical pharmacokinetics 20020101
Interindividual variability of the clinical pharmacokinetics of methadone: implications for the treatment of opioid dependence. Clinical pharmacokinetics 20020101
Interactions between antiretroviral drugs and drugs used for the therapy of the metabolic complications encountered during HIV infection. Clinical pharmacokinetics 20020101
NNRTI plus PI combinations in the perspective of nucleoside-sparing or nucleoside-failing antiretroviral regimens. AIDS reviews 20020101
Hepatic adverse events during highly active antiretroviral therapy containing nevirapine: a case report. Annals of clinical microbiology and antimicrobials 20020101
Stavudine once daily. Drugs 20020101
A comparative study reveals that a regimen containing sustiva provides an effective alternative to protease inhibitor-based therapy. The Journal of the Association of Nurses in AIDS Care : JANAC 20020101
Discovery of second generation quinazolinone non-nucleoside reverse transcriptase inhibitors of HIV-1. Progress in medicinal chemistry 20020101
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[Efficiency and side effects of antiretroviral treatment of HIV infected pregnant women]. Zentralblatt fur Gynakologie 20020101
Management of protease inhibitor-associated hyperlipidemia. American journal of cardiovascular drugs : drugs, devices, and other interventions 20020101
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Higher efavirenz plasma levels correlate with development of insomnia. Journal of acquired immune deficiency syndromes (1999) 20011201
Changes in metabolic parameters and body shape after replacement of protease inhibitor With efavirenz in virologically controlled HIV-1-positive persons: single-arm observational cohort. Journal of acquired immune deficiency syndromes (1999) 20011201
Skin eruption 8 days after a single dose of efavirenz-containing combination therapy. Japanese journal of infectious diseases 20011201
Virological and immunological responses to a once-a-day antiretroviral regimen with didanosine, lamivudine and efavirenz. Antiviral therapy 20011201
Electronic and resonance effects on the ionization of structural analogues of efavirenz. AAPS pharmSci 20011201
The stereoselective targeting of a specific enzyme-substrate complex is the molecular mechanism for the synergic inhibition of HIV-1 reverse transcriptase by (R)-(-)-PPO464: a novel generation of nonnucleoside inhibitors. The Journal of biological chemistry 20011130
[Antiviral therapy of HIV infection in adults]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20011130
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Comparison of NNRTIs in antiretroviral-experienced patients. International journal of STD & AIDS 20011101
Factors affecting adherence and convenience in antiretroviral therapy. International journal of STD & AIDS 20011101
Other issues: penetration into sanctuary sites, immune reconstitution and NNRTI sequencing. International journal of STD & AIDS 20011101
Resistance profile and cross-resistance of HIV-1 among patients failing a non-nucleoside reverse transcriptase inhibitor-containing regimen. Journal of medical virology 20011101
Hepatotoxicity with antiretroviral treatment of pregnant women. Obstetrics and gynecology 20011101
Phylogenetic analysis of reverse transcriptase in antiretroviral drug-naive Korean HIV type 1 patients. AIDS research and human retroviruses 20011101
Synthesis and anti-HIV-1 activity of new delavirdine analogues carrying arylpyrrole moieties. Chemical & pharmaceutical bulletin 20011101
Prevalence of adverse events associated with potent antiretroviral treatment: Swiss HIV Cohort Study. Lancet (London, England) 20011020
Penetration of efavirenz into the male genital tract: drug concentrations and antiviral activity in semen and blood of HIV-1-infected men. AIDS (London, England) 20011019
Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors. Journal of molecular biology 20010928
Response to first protease inhibitor- and efavirenz-containing antiretroviral combination therapy. The Swiss HIV Cohort Study. AIDS (London, England) 20010928
Efavirenz-induced psychosis. AIDS (London, England) 20010928
Comparison of initial combination antiretroviral therapy with a single protease inhibitor, ritonavir and saquinavir, or efavirenz. AIDS (London, England) 20010907
Evolution of anti-HIV drug candidates. Part 3: Diarylpyrimidine (DAPY) analogues. Bioorganic & medicinal chemistry letters 20010903
Mismatched double-stranded RNA (polyI-polyC(12)U) is synergistic with multiple anti-HIV drugs and is active against drug-sensitive and drug-resistant HIV-1 in vitro. Antiviral research 20010901
Thiosugars. VIII. Preparation of new 4'-thio-L-lyxo pyrimidine nucleoside analogues. Nucleosides, nucleotides & nucleic acids 20010901
Efavirenz may have treatment advantage. AIDS patient care and STDs 20010901
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DPC-083. DuPont Pharmaceuticals. Current opinion in investigational drugs (London, England : 2000) 20010901
Does efavirenz cause breast enlargement? TreatmentUpdate 20010901
Solution structures and reactivities of the mixed aggregates derived from n-butyllithium and vicinal amino alkoxides. Journal of the American Chemical Society 20010822
Non-nucleoside reverse transcriptase inhibitor failure impairs HIV-RNA responses to efavirenz-containing salvage antiretroviral therapy. AIDS (London, England) 20010817
Efavirenz as a substitute for protease inhibitors in HIV-1-infected patients with undetectable plasma viral load on HAART: a median follow-up of 64 weeks. Journal of acquired immune deficiency syndromes (1999) 20010815
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Development and validation of a reverse-phase HPLC method for analysis of efavirenz and its related substances in the drug substance and in a capsule formulation. Journal of pharmaceutical and biomedical analysis 20010501
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Long-term exposure of HIV type 1-infected cell cultures to combinations of the novel quinoxaline GW420867X with lamivudine, abacavir, and a variety of nonnucleoside reverse transcriptase inhibitors. AIDS research and human retroviruses 20000410
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Novel 2,2-dioxide-4,4-disubstituted-1,3-H-2,1,3-benzothiadiazines as non-nucleoside reverse transcriptase inhibitors. Bioorganic & medicinal chemistry letters 20000117
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Urea-PETT compounds as a new class of HIV-1 reverse transcriptase inhibitors. 3. Synthesis and further structure-activity relationship studies of PETT analogues. Journal of medicinal chemistry 19991007
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Patterns of resistance and cross-resistance to human immunodeficiency virus type 1 reverse transcriptase inhibitors in patients treated with the nonnucleoside reverse transcriptase inhibitor loviride. Antimicrobial agents and chemotherapy 19981201
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