APR-246
| Title | Journal |
|---|---|
| Hypoxia-Induced Cisplatin Resistance in Non-Small Cell Lung Cancer Cells Is Mediated by HIF-1α and Mutant p53 and Can Be Overcome by Induction of Oxidative Stress. | Cancers 20180401 |
| p53 Reactivation by PRIMA-1(Met) (APR-246) sensitises (V600E/K)BRAF melanoma to vemurafenib. | European journal of cancer (Oxford, England : 1990) 20160301 |
| PRIMA-1Met/APR-246 induces apoptosis and tumor growth delay in small cell lung cancer expressing mutant p53. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110501 |
| Pharmacological rescue of p53 in cancer cells: the soloist meets the PRIMA donna. | Cell cycle (Georgetown, Tex.) 20110315 |
| Unleash the wild type: restoration of p53 suppressive activity in skin cancer. | Cell cycle (Georgetown, Tex.) 20110301 |
| PRIMA-1Met/APR-246 induces wild-type p53-dependent suppression of malignant melanoma tumor growth in 3D culture and in vivo. | Cell cycle (Georgetown, Tex.) 20110115 |
| p53-Reactivating small molecules induce apoptosis and enhance chemotherapeutic cytotoxicity in head and neck squamous cell carcinoma. | Oral oncology 20110101 |
| Mutant p53 reactivation by PRIMA-1MET induces multiple signaling pathways converging on apoptosis. | Oncogene 20100304 |
| PRIMA-1MET induces nucleolar translocation of Epstein-Barr virus-encoded EBNA-5 protein. | Molecular cancer 20090101 |
| PRIMA-1MET induces mitochondrial apoptosis through activation of caspase-2. | Oncogene 20081120 |