Home Other Building Blocks N1-(2-Aminophenyl)-N8-phenyloctanediamide

N1-(2-Aminophenyl)-N8-phenyloctanediamide

CAS No.:
537034-17-6
Catalog Number:
AG0037O7
Molecular Formula:
C20H25N3O2
Molecular Weight:
339.4314
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
96%
1 week
United States
$140
- +
10mg
96%
1 week
United States
$182
- +
50mg
96%
1 week
United States
$404
- +
100mg
96%
1 week
United States
$682
- +
Product Description
Catalog Number:
AG0037O7
Chemical Name:
N1-(2-Aminophenyl)-N8-phenyloctanediamide
CAS Number:
537034-17-6
Molecular Formula:
C20H25N3O2
Molecular Weight:
339.4314
MDL Number:
MFCD08062139
IUPAC Name:
N'-(2-aminophenyl)-N-phenyloctanediamide
InChI:
InChI=1S/C20H25N3O2/c21-17-12-8-9-13-18(17)23-20(25)15-7-2-1-6-14-19(24)22-16-10-4-3-5-11-16/h3-5,8-13H,1-2,6-7,14-15,21H2,(H,22,24)(H,23,25)
InChI Key:
RFLHBLWLFUFFDZ-UHFFFAOYSA-N
SMILES:
O=C(Nc1ccccc1)CCCCCCC(=O)Nc1ccccc1N
Properties
Complexity:
408  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
339.195g/mol
Formal Charge:
0
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
339.439g/mol
Monoisotopic Mass:
339.195g/mol
Rotatable Bond Count:
9  
Topological Polar Surface Area:
84.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3  
Literature
Title Journal
Histone deacetylase inhibitor BML-210 induces growth inhibition and apoptosis and regulates HDAC and DAPC complex expression levels in cervical cancer cells. Molecular biology reports 20121201
DNA methyltransferase inhibitor RG108 and histone deacetylase inhibitors cooperate to enhance NB4 cell differentiation and E-cadherin re-expression by chromatin remodelling. Cell biology international 20121101
Response of retinoic acid-resistant KG1 cells to combination of retinoic acid with diverse histone deacetylase inhibitors. Annals of the New York Academy of Sciences 20090801
Retinoic acid and histone deacetylase inhibitor BML-210 inhibit proliferation of human cervical cancer HeLa cells. Annals of the New York Academy of Sciences 20061201
The novel histone deacetylase inhibitor BML-210 exerts growth inhibitory, proapoptotic and differentiation stimulating effects on the human leukemia cell lines. European journal of pharmacology 20061107
Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia. Nature chemical biology 20061001
Novel inhibitors of human histone deacetylases: design, synthesis, enzyme inhibition, and cancer cell growth inhibition of SAHA-based non-hydroxamates. Journal of medicinal chemistry 20050224
Thiol-based SAHA analogues as potent histone deacetylase inhibitors. Bioorganic & medicinal chemistry letters 20040621
Novel histone deacetylase inhibitors: design, synthesis, enzyme inhibition, and binding mode study of SAHA-based non-hydroxamates. Bioorganic & medicinal chemistry letters 20031215
Properties