1,2,3,6-Tetrahydro-1,3-dimethyl-N-[4-(1-methylethyl)phenyl]-2,6-dioxo-7H-purine-7-acetamide
| Title | Journal |
|---|---|
| TRPA1 and CGRP antagonists counteract vesicant-induced skin injury and inflammation. | Toxicology letters 20180901 |
| Activation of TRPV3 by Wood Smoke Particles and Roles in Pneumotoxicity. | Chemical research in toxicology 20180521 |
| Zebrafish Locomotor Responses Reveal Irritant Effects of Fine Particulate Matter Extracts and a Role for TRPA1. | Toxicological sciences : an official journal of the Society of Toxicology 20180201 |
| Role of TRPA1 in acute cardiopulmonary toxicity of inhaled acrolein. | Toxicology and applied pharmacology 20170601 |
| Carvacrol reduces irinotecan-induced intestinal mucositis through inhibition of inflammation and oxidative damage via TRPA1 receptor activation. | Chemico-biological interactions 20161225 |
| Effects of Food Components That Activate TRPA1 Receptors on Mucosal Ion Transport in the Mouse Intestine. | Nutrients 20161001 |
| Activation of transient receptor potential ankyrin-1 (TRPA1) in lung cells by wood smoke particulate material. | Chemical research in toxicology 20130520 |
| Antagonism of the transient receptor potential ankyrin 1 (TRPA1) attenuates hyperalgesia and urinary bladder overactivity in cyclophosphamide-induced haemorrhagic cystitis. | Chemico-biological interactions 20130425 |
| Lack of transient receptor potential melastatin 8 activation by phthalate esters that enhance contact hypersensitivity in mice. | Toxicology letters 20130313 |
| Stimulation of human TRPA1 channels by clinical concentrations of the antirheumatic drug auranofin. | American journal of physiology. Cell physiology 20130215 |
| Role of transient receptor potential ion channels and evoked levels of neuropeptides in a formaldehyde-induced model of asthma in BALB/c mice. | PloS one 20130101 |
| Transient receptor potential ankyrin 1 activation enhances hapten sensitization in a T-helper type 2-driven fluorescein isothiocyanate-induced contact hypersensitivity mouse model. | Toxicology and applied pharmacology 20121101 |
| Involvement of the endogenous hydrogen sulfide/Ca(v) 3.2 T-type Ca2+ channel pathway in cystitis-related bladder pain in mice. | British journal of pharmacology 20121001 |
| Transient receptor potential channels mediate the tussive response to prostaglandin E2 and bradykinin. | Thorax 20121001 |
| Analysis of transient receptor potential ankyrin 1 (TRPA1) in frogs and lizards illuminates both nociceptive heat and chemical sensitivities and coexpression with TRP vanilloid 1 (TRPV1) in ancestral vertebrates. | The Journal of biological chemistry 20120831 |
| TRPA1-like channels enhance glycinergic transmission in medullary dorsal horn neurons. | Journal of neurochemistry 20120801 |
| Transient receptor potential canonical 3 (TRPC3) is required for IgG immune complex-induced excitation of the rat dorsal root ganglion neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20120711 |
| TRPA1 is functionally expressed in melanoma cells but is not critical for impaired proliferation caused by allyl isothiocyanate or cinnamaldehyde. | Naunyn-Schmiedeberg's archives of pharmacology 20120601 |
| Presynaptic enhancement by eugenol of spontaneous excitatory transmission in rat spinal substantia gelatinosa neurons is mediated by transient receptor potential A1 channels. | Neuroscience 20120517 |
| TRPA1 and TRPV4 mediate paclitaxel-induced peripheral neuropathy in mice via a glutathione-sensitive mechanism. | Pflugers Archiv : European journal of physiology 20120401 |
| Activation of transient receptor potential ankyrin 1 evokes nociception through substance P release from primary sensory neurons. | Journal of neurochemistry 20120301 |
| Ocular dryness excites two classes of corneal afferent neurons implicated in basal tearing in rats: involvement of transient receptor potential channels. | Journal of neurophysiology 20120215 |
| Tricyclic 3,4-dihydropyrimidine-2-thione derivatives as potent TRPA1 antagonists. | Bioorganic & medicinal chemistry letters 20120115 |
| A role for sensory nerves in the late asthmatic response. | Thorax 20120101 |
| TRPA1 contributes to the acute inflammatory response and mediates carrageenan-induced paw edema in the mouse. | Scientific reports 20120101 |
| Sensitivity of bronchopulmonary receptors to cold and heat mediated by transient receptor potential cation channel subtypes in an ex vivo rat lung preparation. | Respiratory physiology & neurobiology 20110815 |
| Transient receptor potential ankyrin 1 is expressed by inhibitory motoneurons of the mouse intestine. | Gastroenterology 20110801 |
| TRPA1 contributes to specific mechanically activated currents and sensory neuron mechanical hypersensitivity. | The Journal of physiology 20110715 |
| Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation. | Pain 20110701 |
| The involvement of TRPA1 channel activation in the inflammatory response evoked by topical application of cinnamaldehyde to mice. | Life sciences 20110620 |
| TRPA1 receptor modulation attenuates bladder overactivity induced by spinal cord injury. | American journal of physiology. Renal physiology 20110501 |
| Synergistic role of TRPV1 and TRPA1 in pancreatic pain and inflammation. | Gastroenterology 20110401 |
| Human dental pulp fibroblasts express the 'cold-sensing' transient receptor potential channels TRPA1 and TRPM8. | Journal of endodontics 20110401 |
| Spinal transient receptor potential ankyrin 1 channel contributes to central pain hypersensitivity in various pathophysiological conditions in the rat. | Pain 20110301 |
| TRPA1 receptors mediate environmental irritant-induced meningeal vasodilatation. | Pain 20110101 |
| Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20101201 |
| Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents. | Journal of medicinal chemistry 20100722 |
| Chemo-nociceptive signalling from the colon is enhanced by mild colitis and blocked by inhibition of transient receptor potential ankyrin 1 channels. | British journal of pharmacology 20100701 |
| Nitro-oleic acid inhibits firing and activates TRPV1- and TRPA1-mediated inward currents in dorsal root ganglion neurons from adult male rats. | The Journal of pharmacology and experimental therapeutics 20100601 |
| Involvement of TRPA1 in ET-1-induced pain-like behavior in mice. | Neuroreport 20100217 |
| Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents. | British journal of pharmacology 20091101 |
| Mediating roles of the vanilloid receptor TRPV1 in activation of rat primary afferent nociceptive neurons by formaldehyde. | Sheng li xue bao : [Acta physiologica Sinica] 20091025 |
| A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma. | Proceedings of the National Academy of Sciences of the United States of America 20090602 |
| HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity. | Molecular pain 20080101 |
| TRPA1 mediates formalin-induced pain. | Proceedings of the National Academy of Sciences of the United States of America 20070814 |