Ginkgo biloba extract (GbE) enhances the anti-atherogenic effect of cilostazol by inhibiting ROS generation.

Experimental & molecular medicine 20120531

Effect of Ginkgo biloba special extract EGb 761® on human cytochrome P450 activity: a cocktail interaction study in healthy volunteers.

European journal of clinical pharmacology 20120501

A single amino acid determines the toxicity of Ginkgo biloba extracts.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120501

Preconditioning with Ginkgo biloba (EGb 761®) provides neuroprotection through HO1 and CRMP2.

Neurobiology of disease 20120401

Different neuroprotective responses of Ginkgolide B and bilobalide, the two Ginkgo components, in ischemic rats with hyperglycemia.

European journal of pharmacology 20120227

The phosphatidyl inositol 3 kinase-glycogen synthase kinase 3β pathway mediates bilobalide-induced reduction in amyloid β-peptide.

Neurochemical research 20120201

Ginkgo biloba extract attenuates warfarin-mediated anticoagulation through induction of hepatic cytochrome P450 enzymes by bilobalide in mice.

Phytomedicine : international journal of phytotherapy and phytopharmacology 20120115

Species-dependent and receptor-selective action of bilobalide on the function of constitutive androstane receptor and pregnane X receptor.

Drug metabolism and disposition: the biological fate of chemicals 20120101

Ginkgo biloba responds to herbivory by activating early signaling and direct defenses.

PloS one 20120101

An overview of the evidence and mechanisms of herb-drug interactions.

Frontiers in pharmacology 20120101

The bad, the good, and the ugly about oxidative stress.

Oxidative medicine and cellular longevity 20120101

Mouse models of Down syndrome as a tool to unravel the causes of mental disabilities.

Neural plasticity 20120101

Ginkgo biloba extract EGB761 protects against aging-associated diastolic dysfunction in cardiomyocytes of D-galactose-induced aging rat.

Oxidative medicine and cellular longevity 20120101

Neuroprotective effects of bilobalide are accompanied by a reduction of ischemia-induced glutamate release in vivo.

Brain research 20111124

Isoform-selective activation of human constitutive androstane receptor by Ginkgo biloba extract: functional analysis of the SV23, SV24, and SV25 splice variants.

The Journal of pharmacology and experimental therapeutics 20111101

Effects of Ginkgo biloba constituents on fruit-infesting behavior of codling moth (Cydia pomonella) in apples.

Journal of agricultural and food chemistry 20111026

Bilobalide protects mitochondrial function in ovariectomized rats by up-regulation of mRNA and protein expression of cytochrome c oxidase subunit I.

Journal of molecular neuroscience : MN 20111001

EGb 761 (Ginkgo biloba) protects cochlear hair cells against ototoxicity induced by gentamicin via reducing reactive oxygen species and nitric oxide-related apoptosis.

The Journal of nutritional biochemistry 20110901

The facilitative effects of bilobalide, a unique constituent of Ginkgo biloba, on synaptic transmission and plasticity in hippocampal subfields.

The journal of physiological sciences : JPS 20110901

MicroRNA expression is differentially altered by xenobiotic drugs in different human cell lines.

Biopharmaceutics & drug disposition 20110901

Pancreatic lipase inhibition activity of trilactone terpenes of Ginkgo biloba.

Journal of enzyme inhibition and medicinal chemistry 20110801

Bilobalide regulates soluble amyloid precursor protein release via phosphatidyl inositol 3 kinase-dependent pathway.

Neurochemistry international 20110801

Binding sites for bilobalide, diltiazem, ginkgolide, and picrotoxinin at the 5-HT3 receptor.

Molecular pharmacology 20110701

Modulation of CYP1A1 activity by a Ginkgo biloba extract in the human intestinal Caco-2 cells.

Toxicology letters 20110510

Ginkgolide B and bilobalide block the pore of the 5-HT₃receptor at a location that overlaps the picrotoxin binding site.

Neuropharmacology 20110201

Paeoniae alba Radix Promotes Peripheral Nerve Regeneration.

Evidence-based complementary and alternative medicine : eCAM 20110101

Neuron Regeneration and Proliferation Effects of Danshen and Tanshinone IIA.

Evidence-based complementary and alternative medicine : eCAM 20110101

Ginkgo biloba extract (EGb761) inhibits mitochondria-dependent caspase pathway and prevents apoptosis in hypoxia-reoxygenated cardiomyocytes.

Chinese medicine 20110101

Drug discovery from Chinese medicine against neurodegeneration in Alzheimer's and vascular dementia.

Chinese medicine 20110101

Alleviating neuropsychiatric symptoms in dementia: the effects of Ginkgo biloba extract EGb 761. Findings from a randomized controlled trial.

Neuropsychiatric disease and treatment 20110101

EGb761, a Ginkgo biloba extract, is effective against atherosclerosis in vitro, and in a rat model of type 2 diabetes.

PloS one 20110101

Flavonoids lower Alzheimer's Aβ production via an NFκB dependent mechanism.

Bioinformation 20110101

Evaluation of Antioxidant and Cerebroprotective Effect of Medicago sativa Linn. against Ischemia and Reperfusion Insult.

Evidence-based complementary and alternative medicine : eCAM 20110101

Ginkgo biloba extract in the treatment of tinnitus: a systematic review.

Neuropsychiatric disease and treatment 20110101

Examining brain-cognition effects of ginkgo biloba extract: brain activation in the left temporal and left prefrontal cortex in an object working memory task.

Evidence-based complementary and alternative medicine : eCAM 20110101

The alteration of components in the fermented Hwangryunhaedok-tang and its neuroprotective activity.

Pharmacognosy magazine 20110101

The chemopreventive effect of Ginkgo biloba and Silybum marianum extracts on hepatocarcinogenesis in rats.

Cancer cell international 20110101

Antibacterial activities of Ginkgo biloba L. leaf extracts.

TheScientificWorldJournal 20110101

Environmental enrichment decreases GABAergic inhibition and improves cognitive abilities, synaptic plasticity, and visual functions in a mouse model of Down syndrome.

Frontiers in cellular neuroscience 20110101

Human pregnane X receptor agonism by Ginkgo biloba extract: assessment of the role of individual ginkgolides.

The Journal of pharmacology and experimental therapeutics 20101201

Neuroprotective effect of honokiol and magnolol, compounds from Magnolia officinalis, on beta-amyloid-induced toxicity in PC12 cells.

Phytotherapy research : PTR 20101001

Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells.

Apoptosis : an international journal on programmed cell death 20100601

Intestinal and blood-brain barrier permeability of ginkgolides and bilobalide: in vitro and in vivo approaches.

Planta medica 20100401

Pharmacokinetics of bilobalide, ginkgolide A and B after administration of three different Ginkgo biloba L. preparations in humans.

Phytotherapy research : PTR 20100301

Inhibition of intestinal and hepatic glucuronidation of mycophenolic acid by Ginkgo biloba extract and flavonoids.

Drug metabolism and disposition: the biological fate of chemicals 20100201

The Ginkgo biloba extract EGb 761(R) and its main constituent flavonoids and ginkgolides increase extracellular dopamine levels in the rat prefrontal cortex.

British journal of pharmacology 20100201

Effects of poly-gamma-glutamic acid on serum and brain concentrations of glutamate and GABA in diet-induced obese rats.

Nutrition research and practice 20100201

Ginkgo biloba extract in Alzheimer's disease: from action mechanisms to medical practice.

International journal of molecular sciences 20100101

Cinnamomum cassia bark in two herbal formulas increases life span in Caenorhabditis elegans via insulin signaling and stress response pathways.

PloS one 20100101

EGb761 protects motoneurons against avulsion-induced oxidative stress in rats.

Journal of brachial plexus and peripheral nerve injury 20100101

Neuroprotective properties of chitosan and its derivatives.

Marine drugs 20100101

Ginkgo biloba extract ameliorates oxidative phosphorylation performance and rescues abeta-induced failure.

PloS one 20100101

Improved mitochondrial function in brain aging and Alzheimer disease - the new mechanism of action of the old metabolic enhancer piracetam.

Frontiers in neuroscience 20100101

Assessment of health claims, content, and safety of herbal supplements containing Ginkgo biloba.

Food & nutrition research 20100101

Brain permeability of bilobalide as probed by microdialysis before and after middle cerebral artery occlusion in mice.

Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20100101

Optimization of extraction technique and validation of developed RP-HPLC-ELSD method for determination of terpene trilactones in Ginkgo biloba leaves.

Journal of pharmaceutical and biomedical analysis 20091205

Gene Regulatory Effects of Ginkgo biloba Extract and Its Flavonol and Terpenelactone Fractions in Mouse Brain.

Journal of clinical biochemistry and nutrition 20091101

Validation of an LC-MS/MS assay of terpene trilactones in Ginkgo biloba extracts and pharmaceutical formulations through standard addition method.

Journal of pharmaceutical and biomedical analysis 20091015

Development of an alternative method for determination of terpene lactones in ginkgo dry extract.

Pharmeuropa bio & scientific notes 20091001

Liquid chromatography/atmospheric pressure chemical ionization ion trap mass spectrometry of bilobalide in plasma and brain of rats after oral administration of its phospholipidic complex.

Journal of pharmaceutical and biomedical analysis 20090908

Inhibition of human CYP2B6-catalyzed bupropion hydroxylation by Ginkgo biloba extract: effect of terpene trilactones and flavonols.

Drug metabolism and disposition: the biological fate of chemicals 20090901

Modulation of CYP1B1 and CYP1A1 gene expression and activation of aryl hydrocarbon receptor by Ginkgo biloba extract in MCF-10A human mammary epithelial cells.

Canadian journal of physiology and pharmacology 20090901

The mixture of procyanidins extracted from the lotus seed pod and bilobalide ameliorates scopolamine-induced memory impairment in mice.

Neuroscience bulletin 20090801

Adult reversal of cognitive phenotypes in neurodevelopmental disorders.

Journal of neurodevelopmental disorders 20090601

Influence of antivitamins ginkgotoxin 5'-phosphate and deoxypyridoxine 5'-phosphate on human pyridoxine 5'-phosphate oxidase.

Planta medica 20090501

Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways.

Pharmaceutical research 20090401

Chemical analysis and quality control of Ginkgo biloba leaves, extracts, and phytopharmaceuticals.

Journal of chromatography. A 20090313

Time-dependent induction of hepatic cytochrome P450 enzyme activity and mRNA expression by bilobalide in rats.

Journal of pharmacological sciences 20090301

Effect of biotic elicitors on the accumulation of bilobalide and ginkgolides in Ginkgo biloba cell cultures.

Journal of biotechnology 20090101

Column liquid chromatography/electrospray ionization-time of flight-mass spectrometry and ultraperformance column liquid chromatography/mass spectrometry methods for the determination of ginkgolides and bilobalide in the leaves of Ginkgo biloba and dietary supplements.

Journal of AOAC International 20090101

Bilobalide modulates serotonin-controlled behaviors in the nematode Caenorhabditis elegans.

BMC neuroscience 20090101

Stimulation of neurogenesis and synaptogenesis by bilobalide and quercetin via common final pathway in hippocampal neurons.

Journal of Alzheimer's disease : JAD 20090101

Ginkgo biloba extract neuroprotective action is dependent on heme oxygenase 1 in ischemic reperfusion brain injury.

Stroke 20081201

Influence of elevated carbon dioxide and ozone on the foliar nonvolatile terpenoids in ginkgo biloba.

Bulletin of environmental contamination and toxicology 20081101

Induction of cytochrome P450s by terpene trilactones and flavonoids of the Ginkgo biloba extract EGb 761 in rats.

Xenobiotica; the fate of foreign compounds in biological systems 20080501

Bilobalide inhibits 6-OHDA-induced activation of NF-kappaB and loss of dopaminergic neurons in rat substantia nigra.

Acta pharmacologica Sinica 20080501

Subunit-specific potentiation of recombinant glycine receptors by NV-31, a bilobalide-derived compound.

Neuroscience letters 20080418

Spectroscopic investigation of Ginkgo biloba terpene trilactones and their interaction with amyloid peptide Abeta(25-35).

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080401

Role of glycine receptors and glycine release for the neuroprotective activity of bilobalide.

Brain research 20080327

Simultaneous determination of ginkgolides A, B, C and bilobalide in plasma by LC-MS/MS and its application to the pharmacokinetic study of Ginkgo biloba extract in rats.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080315

Simultaneous determination of ginkgo flavonoids and terpenoids in plasma: ammonium formate in LC mobile phase enhancing electrospray ionization efficiency and capacity.

Journal of the American Society for Mass Spectrometry 20080301

Chemical markers for the quality control of herbal medicines: an overview.

Chinese medicine 20080101

Recent advances in the compound-oriented and pattern-oriented approaches to the quality control of herbal medicines.

Chinese medicine 20080101

Induction of cytochrome P450 3A by the Ginkgo biloba extract and bilobalides in human and rat primary hepatocytes.

Drug metabolism letters 20080101

Restoration of impaired phosphorylation of cyclic AMP response element-binding protein (CREB) by EGb 761 and its constituents in Abeta-expressing neuroblastoma cells.

The European journal of neuroscience 20071101

Characterization of a suite of ginkgo-containing standard reference materials.

Analytical and bioanalytical chemistry 20070901

Effect of Ginkgo biloba extract on oxidative metabolism of valproic acid in hepatic microsomes from donors with the CYP2C9*1/*1 genotype.

Canadian journal of physiology and pharmacology 20070901

Drug treatment improves memory in mice.

Down's syndrome, research and practice : the journal of the Sarah Duffen Centre 20070701

Acute cognitive effects of standardised Ginkgo biloba extract complexed with phosphatidylserine.

Human psychopharmacology 20070601

Bilobalide in Ginkgo biloba extract is a major substance inducing hepatic CYPs.

The Journal of pharmacy and pharmacology 20070601

Treating senile dementia with traditional Chinese medicine.

Clinical interventions in aging 20070601

Role of GABAergic antagonism in the neuroprotective effects of bilobalide.

Brain research 20070112

Bilobalide prevents ischemia-induced edema formation in vitro and in vivo.

Neuroscience 20070105

Single-laboratory validation for the determination of terpene lactones in Ginkgo biloba dietary supplement crude materials and finished products by high-performance liquid chromatography with evaporative light-scattering detection.

Journal of AOAC International 20070101

Analysis of flavonol aglycones and terpenelactones in Ginkgo biloba extract: A comparison of high-performance thin-layer chromatography and column high-performance liquid chromatography.

Journal of AOAC International 20070101

Validation of capillary gas chromatographic method for determination of bilobalide and ginkgolides A, B, C in Ginkgo biloba dry and liquid extracts.

Acta poloniae pharmaceutica 20070101

Cardiovascular pharmacology of sinomenine: the mechanical and electropharmacological actions.

Drug target insights 20070101

A screening platform for compounds with potential immuno-regulatory activities using human cord blood mononuclear cells.

Combinatorial chemistry & high throughput screening 20061201

In vitro peroxynitrite scavenging activity of 6-hydroxykynurenic acid and other flavonoids from Gingko biloba yellow leaves.

Archives of pharmacal research 20061201

Analysis of ginkgolides and bilobalide in food products using LC-APCI-MS.

Journal of pharmaceutical and biomedical analysis 20060828

Application of reverse-flow micellar electrokinetic chromatography for the simultaneous determination of flavonols and terpene trilactones in Ginkgo biloba dosage forms.

Journal of chromatography. A 20060728

Molecular determinants of ginkgolide binding in the glycine receptor pore.

Journal of neurochemistry 20060701

Effect of Ginkgo biloba extract on procarcinogen-bioactivating human CYP1 enzymes: identification of isorhamnetin, kaempferol, and quercetin as potent inhibitors of CYP1B1.

Toxicology and applied pharmacology 20060515

Effect of supplementing terpenoid biosynthetic precursors on the accumulation of bilobalide and ginkgolides in Ginkgo biloba cell cultures.

Journal of biotechnology 20060503

Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Determination of terpene trilactones in Ginkgo biloba solid oral dosage forms using HPLC with evaporative light scattering detection.

Journal of pharmaceutical and biomedical analysis 20060411

Distinct role of bilobalide and ginkgolide A in the modulation of rat CYP2B1 and CYP3A23 gene expression by Ginkgo biloba extract in cultured hepatocytes.

Drug metabolism and disposition: the biological fate of chemicals 20060201

Identification of class 2 1-deoxy-D-xylulose 5-phosphate synthase and 1-deoxy-D-xylulose 5-phosphate reductoisomerase genes from Ginkgo biloba and their transcription in embryo culture with respect to ginkgolide biosynthesis.

Planta medica 20060201

Mixed antagonistic effects of bilobalide at rho1 GABAC receptor.

Neuroscience 20060101

Quantitative determination of major active components in Ginkgo biloba dietary supplements by liquid chromatography/mass spectrometry.

Rapid communications in mass spectrometry : RCM 20060101

[Quantitative determination of ginkgolides by liquid chromatography-electrospray mass spectrometry].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20051201

Suppression of pacemaker activity by Ginkgo biloba extract and its main constituent, bilobalide in rat sino-atrial nodal cells.

Life sciences 20051119

A picrotoxin-specific conformational change in the glycine receptor M2-M3 loop.

The Journal of biological chemistry 20051028

Preparative isolation of terpene trilactones from Ginkgo biloba leaves.

Journal of chromatography. A 20051021

Development of a ginkgo biloba fingerprint chromatogram with UV and evaporative light scattering detection and optimization of the evaporative light scattering detector operating conditions.

Journal of chromatography. A 20050902

Terpene trilactones from Gingko biloba: from ancient times to the 21st century.

Bioorganic & medicinal chemistry 20050901

Ginkgolides and bilobalide: their physical, chromatographic and spectroscopic properties.

Bioorganic & medicinal chemistry 20050901

Age-related changes in the vasodilating actions of Ginkgo biloba extract and its main constituent, bilobalide, in rat aorta.

Clinica chimica acta; international journal of clinical chemistry 20050401

Biological activities of Ginkgo extracts.

Phytomedicine : international journal of phytotherapy and phytopharmacology 20050401

Liquid chromatography/electrospray tandem mass spectrometry of terpenoid lactones in Ginkgo biloba.

Journal of mass spectrometry : JMS 20050301

Effects of ginkgo biloba extract on cation currents in rat ventricular myocytes.

Life sciences 20050121

[Applications of two-dimensional liquid chromatography coupled to mass spectrometry for the separation and identification of compounds in ginkgo biloba extracts].

Se pu = Chinese journal of chromatography 20050101

HPLC determination of certain flavonoids and terpene lactones in selected Ginkgo biloba L. phytopharmaceuticals.

Farmaco (Societa chimica italiana : 1989) 20050101

Isolation of ginkgolides A, B, C, J and bilobalide from G. biloba extracts.

Phytochemistry 20041101

A method for extraction and quantification of Ginkgo terpene trilactones.

Analytical chemistry 20040801

Inhibition of human cytochromes P450 by components of Ginkgo biloba.

The Journal of pharmacy and pharmacology 20040801

Preventive effects of extract of leaves of ginkgo (Ginkgo biloba) and its component bilobalide on azoxymethane-induced colonic aberrant crypt foci in rats.

Cancer letters 20040716

Determination of ginkgolide A, B, and bilobalide in biloba L. extracts by microdialysis-HPLC.

Analytical and bioanalytical chemistry 20040601

[Studies on the cell growth, differentiation and terpene lactone accumulation in Ginkgo biloba cell suspension cultures].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20040501

Electropharmacological actions of Ginkgo biloba extract on vascular smooth and heart muscles.

Clinica chimica acta; international journal of clinical chemistry 20040401

Chemistry and biology of terpene trilactones from Ginkgo biloba.

Angewandte Chemie (International ed. in English) 20040319

Effect of bilobalide on peripheral nerve regeneration.

Biomaterials 20040201

Comparative vasodilating actions among terpenoids and flavonoids contained in Ginkgo biloba extract.

Clinica chimica acta; international journal of clinical chemistry 20040101

Effect of Ginkgo biloba extract on rat hepatic microsomal CYP1A activity: role of ginkgolides, bilobalide, and flavonols.

Canadian journal of physiology and pharmacology 20040101

Sample preparation and determination of ginkgo terpene trilactones in selected beverage, snack, and dietary supplement products by liquid chromatography with evaporative light-scattering detection.

Journal of AOAC International 20040101

Ginkgo biloba--an appraisal.

Kathmandu University medical journal (KUMJ) 20040101

Terpene trilactones from Ginkgo biloba are antagonists of cortical glycine and GABA(A) receptors.

The Journal of biological chemistry 20031205

Analysis of ginkgolides and bilobalide in Ginkgo biloba L. extract injections by high-performance liquid chromatography with evaporative light scattering detection.

Journal of pharmaceutical and biomedical analysis 20031124

An anxiolytic-like effect of Ginkgo biloba extract and its constituent, ginkgolide-A, in mice.

Journal of natural products 20031001

Liquid chromatography/atmospheric pressure chemical ionization ion trap mass spectrometry of terpene lactones in plasma of animals.

Journal of pharmaceutical and biomedical analysis 20030808

Pharmacological studies supporting the therapeutic use of Ginkgo biloba extract for Alzheimer's disease.

Pharmacopsychiatry 20030601

Cognitive and other behavioral effects of EGb 761 in animal models.

Pharmacopsychiatry 20030601

Pharmacokinetics of Ginkgo biloba extracts.

Pharmacopsychiatry 20030601

Structure-activity studies with Ginkgo biloba extract constituents as receptor-gated chloride channel blockers and modulators.

Pharmacopsychiatry 20030601

Excitotoxic hippocampal membrane breakdown and its inhibition by bilobalide: role of chloride fluxes.

Pharmacopsychiatry 20030601

Effects of bilobalide on cerebral amino acid neurotransmission.

Pharmacopsychiatry 20030601

Neuroprotective effects of bilobalide, a component of Ginkgo biloba extract (EGb 761) in global brain ischemia and in excitotoxicity-induced neuronal death.

Pharmacopsychiatry 20030601

Mechanisms for the vasodilations induced by Ginkgo biloba extract and its main constituent, bilobalide, in rat aorta.

Life sciences 20030425

Bilobalide, a sesquiterpene trilactone from Ginkgo biloba, is an antagonist at recombinant alpha1beta2gamma2L GABA(A) receptors.

European journal of pharmacology 20030307

Quantitative analysis of bilobalide and ginkgolides from Ginkgo biloba leaves and Ginkgo products using (1)H-NMR.

Chemical & pharmaceutical bulletin 20030201

Development and validation of a gas chromatographic-mass spectrometric method for simultaneous identification and quantification of marker compounds including bilobalide, ginkgolides and flavonoids in Ginkgo biloba L. extract and pharmaceutical preparations.

Journal of chromatography. A 20030131

Homocysteine stimulates inducible nitric oxide synthase expression in macrophages: antagonizing effect of ginkgolides and bilobalide.

Molecular and cellular biochemistry 20030101

EGb 761: ginkgo biloba extract, Ginkor.

Drugs in R&D 20030101

Effects of ginkgo biloba extract and bilobalide, a main constituent, on the ionic currents in guinea pig ventricular cardiomyocytes.

Arzneimittel-Forschung 20030101

Bilobalide and neuroprotection.

Pharmacological research 20021201

Influence of pharmaceutical quality on the bioavailability of active components from Ginkgo biloba preparations.

The Journal of pharmacy and pharmacology 20021101

Efficient extraction of ginkgolides and bilobalide from Ginkgo biloba leaves.

Journal of natural products 20021001

Identification and the retention index of bilobalide and ginkgolides using capillary gas chromatography.

Journal of chromatographic science 20021001

What is Ginkgo biloba extract EGb 761? An overview--from molecular biology to clinical medicine.