Home Other Building Blocks Mono-methyl succinate

Mono-methyl succinate

CAS No.:
3878-55-5
Catalog Number:
AG0037JD
Molecular Formula:
C5H8O4
Molecular Weight:
132.1146
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
95%
In Stock USA
United States
$13
- +
25g
95%
In Stock USA
United States
$19
- +
100g
95%
In Stock USA
United States
$63
- +
500g
95%
In Stock USA
United States
$188
- +
Product Description
Catalog Number:
AG0037JD
Chemical Name:
Mono-methyl succinate
CAS Number:
3878-55-5
Molecular Formula:
C5H8O4
Molecular Weight:
132.1146
MDL Number:
MFCD00002788
IUPAC Name:
4-methoxy-4-oxobutanoic acid
InChI:
InChI=1S/C5H8O4/c1-9-5(8)3-2-4(6)7/h2-3H2,1H3,(H,6,7)
InChI Key:
JDRMYOQETPMYQX-UHFFFAOYSA-N
SMILES:
COC(=O)CCC(=O)O
EC Number:
223-408-2
UNII:
YA2V724S0A
NSC Number:
511
Properties
Complexity:
118  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
132.042g/mol
Formal Charge:
0
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
132.115g/mol
Monoisotopic Mass:
132.042g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
63.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0
Literature
Title Journal
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Supplementation of pyruvate prevents palmitate-induced impairment of glucose uptake in C2 myotubes. Molecular and cellular endocrinology 20111015
Metabolic oxidative stress elicited by the copper(II) complex [Cu(isaepy)2] triggers apoptosis in SH-SY5Y cells through the induction of the AMP-activated protein kinase/p38MAPK/p53 signalling axis: evidence for a combined use with 3-bromopyruvate in neuroblastoma treatment. The Biochemical journal 20110801
Phagocyte-like NADPH oxidase generates ROS in INS 832/13 cells and rat islets: role of protein prenylation. American journal of physiology. Regulatory, integrative and comparative physiology 20110301
Development of an orthodontic elastic material using EMA-based resin combined with 1-butanol. Dental materials journal 20110101
2-Phenyl-biguanidinium hydrogen succinate methanol monosolvate. Acta crystallographica. Section E, Structure reports online 20101201
Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion. American journal of physiology. Endocrinology and metabolism 20090601
Total synthesis of the natural succinate derivative of 5-(hydroxymethyl)furfural isolated from the Noni fruit (Morinda citrifolia). Natural product research 20090101
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Acetoacetate and beta-hydroxybutyrate in combination with other metabolites release insulin from INS-1 cells and provide clues about pathways in insulin secretion. American journal of physiology. Cell physiology 20080201
Ca2+, NAD(P)H and membrane potential changes in pancreatic beta-cells by methyl succinate: comparison with glucose. The Biochemical journal 20070401
Methyl succinate antagonises biguanide-induced AMPK-activation and death of pancreatic beta-cells through restoration of mitochondrial electron transfer. British journal of pharmacology 20070401
Synergistic potent insulin release by combinations of weak secretagogues in pancreatic islets and INS-1 cells. The Journal of biological chemistry 20070302
Identification of monomenthyl succinate in natural mint extracts by LC-ESI-MS-MS and GC-MS. Journal of agricultural and food chemistry 20060628
Fumarate reductase: structural and mechanistic insights from the catalytic reduction of 2-methylfumarate. FEBS letters 20060306
Selective loss of glucose-induced amplification of insulin secretion in mouse pancreatic islets pretreated with sulfonylurea in the absence of fuels. Diabetologia 20051201
P2Y purinergic potentiation of glucose-induced insulin secretion and pancreatic beta-cell metabolism. Diabetes 20041201
Liquid chromatographic determination of oxaliplatin in blood using post-column derivatization in a microwave field followed by photometric detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031005
Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis. Cell death and differentiation 20030601
Differences between mouse and rat pancreatic islets: succinate responsiveness, malic enzyme, and anaplerosis. American journal of physiology. Endocrinology and metabolism 20020801
Differential effects of hyperlipidemia on insulin secretion in islets of langerhans from hyperglycemic versus normoglycemic rats. Diabetes 20020301
A neuronal isoform of nitric oxide synthase expressed in pancreatic beta-cells controls insulin secretion. Diabetes 20010601
Defective stimulus-secretion coupling in islets of Psammomys obesus, an animal model for type 2 diabetes. Diabetes 20010201
Differential acute and long term actions of succinic acid monomethyl ester exposure on insulin-secreting BRIN-BD11 cells. International journal of experimental diabetes research 20010101
Properties