Home Aminos (8S-cis)-8-Acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione hydrochloride

(8S-cis)-8-Acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione hydrochloride

CAS No.:
23541-50-6
Catalog Number:
AG0037I5
Molecular Formula:
C27H30ClNO10
Molecular Weight:
563.9808
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
96%(HPLC)
In Stock USA
United States
$61
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10mg
96%(HPLC)
In Stock USA
United States
$100
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25mg
96%(HPLC)
In Stock USA
United States
$139
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50mg
96%(HPLC)
In Stock USA
United States
$219
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100mg
96%(HPLC)
In Stock USA
United States
$353
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250mg
96%(HPLC)
In Stock USA
United States
$486
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Product Description
Catalog Number:
AG0037I5
Chemical Name:
(8S-cis)-8-Acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione hydrochloride
CAS Number:
23541-50-6
Molecular Formula:
C27H30ClNO10
Molecular Weight:
563.9808
MDL Number:
MFCD04974507
IUPAC Name:
(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride
InChI:
InChI=1S/C27H29NO10.ClH/c1-10-22(30)14(28)7-17(37-10)38-16-9-27(35,11(2)29)8-13-19(16)26(34)21-20(24(13)32)23(31)12-5-4-6-15(36-3)18(12)25(21)33;/h4-6,10,14,16-17,22,30,32,34-35H,7-9,28H2,1-3H3;1H/t10-,14-,16-,17-,22+,27-;/m0./s1
InChI Key:
GUGHGUXZJWAIAS-QQYBVWGSSA-N
SMILES:
COc1cccc2c1C(=O)c1c(C2=O)c(O)c2c(c1O)[C@@H](O[C@H]1C[C@H](N)[C@@H]([C@@H](O1)C)O)C[C@](C2)(O)C(=O)C.Cl
EC Number:
245-723-4
UNII:
UD984I04LZ
UN Number:
2811
Properties
Complexity:
960  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
6  
Defined Bond Stereocenter Count:
0
Exact Mass:
563.156g/mol
Formal Charge:
0
Heavy Atom Count:
39  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
6  
Isotope Atom Count:
0
Molecular Weight:
563.984g/mol
Monoisotopic Mass:
563.156g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
186A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
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Sequential continuous infusion of fludarabine and cytarabine associated with liposomal daunorubicin (DaunoXome) (FLAD) in primary refractory or relapsed adult acute myeloid leukemia patients. Annals of hematology 20090201
Fluorescence anisotropy of membrane fluidity probes in human erythrocytes incubated with anthracyclines and glutaraldehyde. Bioelectrochemistry (Amsterdam, Netherlands) 20090201
Reversal effect of PI3-K inhibitor LY294002 on P-glycoprotein-mediated multidrug resistance of human leukemia cell line K562/DNR and gastric cancer cell line SGC7901/ADR. Ai zheng = Aizheng = Chinese journal of cancer 20090201
Structure of the transcriptional regulator LmrR and its mechanism of multidrug recognition. The EMBO journal 20090121
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Effect of flavonoids on daunorubicin-induced toxicity in H9c2 Cardiomyoblasts. Phytotherapy research : PTR 20090101
Selective modulation of P-glycoprotein activity by steroidal saponines from Paris polyphylla. Fitoterapia 20090101
A second case of secondary acute myeloblastic leukemia associated with the MLL-KIAA0284 fusion gene. Blood cells, molecules & diseases 20090101
Imatinib is a substrate for various multidrug resistance proteins. Neoplasma 20090101
HIV-associated multicentric Castleman disease. Current opinion in HIV and AIDS 20090101
Magnetic nanoparticle of Fe3O4 and 5-bromotetrandrin interact synergistically to induce apoptosis by daunorubicin in leukemia cells. International journal of nanomedicine 20090101
Reversal of multidrug resistance by magnetic Fe3O4 nanoparticle copolymerizating daunorubicin and 5-bromotetrandrine in xenograft nude-mice. International journal of nanomedicine 20090101
Transcriptional regulation of neutral sphingomyelinase 2 gene expression of a human breast cancer cell line, MCF-7, induced by the anti-cancer drug, daunorubicin. Biochimica et biophysica acta 20090101
Effects of alpha-adrenoceptor antagonist doxazosin on MDR1-mediated multidrug resistance and transcellular transport. Oncology research 20090101
Plasma cardiac necrosis markers C-troponin I and creatine kinase, associated with increased malondialdehyde levels, induced in rabbits by means of 5-aminolevulinic acid injection. Pharmacology 20090101
Testicular function after treatment for acute lymphoblastic leukemia (all) in prepubertal and pubertal boys. Pediatric hematology and oncology 20090101
Cerebellar Purkinje cells incorporate immunoglobulins and immunotoxins in vitro: implications for human neurological disease and immunotherapeutics. Journal of neuroinflammation 20090101
Oncogenic RAS enables DNA damage- and p53-dependent differentiation of acute myeloid leukemia cells in response to chemotherapy. PloS one 20090101
Zygomycosis in a 13 year old girl with T-NHL. Klinische Padiatrie 20090101
Daunorubicin-loaded magnetic nanoparticles of Fe3O4 overcome multidrug resistance and induce apoptosis of K562-n/VCR cells in vivo. International journal of nanomedicine 20090101
Effect of magnetic nanoparticles of Fe3O4 and 5-bromotetrandrine on reversal of multidrug resistance in K562/A02 leukemic cells. International journal of nanomedicine 20090101
Optimal induction and post-remission therapy for AML in first remission. Hematology. American Society of Hematology. Education Program 20090101
Chemotherapy in canine acute megakaryoblastic leukemia: a case report and review of the literature. In vivo (Athens, Greece) 20090101
Effects of chemopreventive citrus phytochemicals on human P-glycoprotein and multidrug resistance protein 1. European journal of pharmacology 20081214
Recurrent episodes of fever and pancytopenia due to haemophagocytosis during maintenance therapy for acute myeloid leukaemia. British journal of haematology 20081201
Minimal residual disease is an important predictive factor of outcome in children with relapsed 'high-risk' acute lymphoblastic leukemia. Leukemia 20081201
Risk factors and decision criteria for intensive chemotherapy in older patients with acute myeloid leukemia. Haematologica 20081201
Liposomal daunorubicin versus standard daunorubicin: long term follow-up of the GIMEMA GSI 103 AMLE randomized trial in patients older than 60 years with acute myelogenous leukaemia. British journal of haematology 20081201
Licoflavone C attenuates the genotoxicity of cancer drugs in human peripheral lymphocytes. Phytotherapy research : PTR 20081201
Translocation (14;14)(q11;q32) with simultaneous involvement of the IGH and CEBPE genes in B-lineage acute lymphoblastic leukemia. Cancer genetics and cytogenetics 20081201
Augmented and standard Berlin-Frankfurt-Munster chemotherapy for treatment of adult acute lymphoblastic leukemia. Leukemia & lymphoma 20081201
CD20 up-regulation in pediatric B-cell precursor acute lymphoblastic leukemia during induction treatment: setting the stage for anti-CD20 directed immunotherapy. Blood 20081115
CD4+/CD56+ Hematodermic neoplasm (plasmacytoid dendritic cell tumor). Dermatology online journal 20081115
The kinase inhibitor LS104 induces apoptosis, enhances cytotoxic effects of chemotherapeutic drugs and is targeting the receptor tyrosine kinase FLT3 in acute myeloid leukemia. Leukemia research 20081101
Improved HPLC method for doxorubicin quantification in rat plasma to study the pharmacokinetics of micelle-encapsulated and liposome-encapsulated doxorubicin formulations. Biomedical chromatography : BMC 20081101
Oral mucositis in acute lymphoblastic leukaemia: analysis of 169 paediatric patients. Oral diseases 20081101
Veno-occlusive disease of the liver during induction therapy for acute lymphoblastic leukemia. International journal of hematology 20081101
Existing and emerging therapeutic options for the treatment of acute myeloid leukemia. Clinical advances in hematology & oncology : H&O 20081101
Future research directions for the treatment of AML. Clinical advances in hematology & oncology : H&O 20081101
[Effects of survivin antisense oligodeoxynucleotide on drug resistance in K562 cells]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20081101
Hydration of drug-DNA complexes: greater water uptake for adriamycin compared to daunomycin. Journal of medicinal chemistry 20081009
Inhibition of P-glycoprotein and multidrug resistance protein 1 by dietary phytochemicals. Cancer chemotherapy and pharmacology 20081001
Wilms' tumor 1 gene mutations independently predict poor outcome in adults with cytogenetically normal acute myeloid leukemia: a cancer and leukemia group B study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081001
Patients with acute myeloid leukemia and RAS mutations benefit most from postremission high-dose cytarabine: a Cancer and Leukemia Group B study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081001
Direct determination of intracellular daunorubicin in intact confluent monolayers of AT1 prostate carcinoma cells using a multiwell-multilabel counter. Analytical biochemistry 20081001
Delivery of daunorubicin to cancer cells with decreased toxicity by association with a lipidic nanoemulsion that binds to LDL receptors. The Journal of pharmacy and pharmacology 20081001
Diffuse large B-cell lymphoma. Hematology/oncology clinics of North America 20081001
Effect of surface chemistry modification of functional gold nanoparticles on the drug accumulation of cancer cells. Journal of biomedical materials research. Part A 20080915
Myeloid sarcoma is associated with superior event-free survival and overall survival compared with acute myeloid leukemia. Cancer 20080915
Initial leukemic gene expression profiles of patients with poor in vivo prednisone response are similar to those of blasts persisting under prednisone treatment in childhood acute lymphoblastic leukemia. Annals of hematology 20080901
Anthracycline toxicity to cardiomyocytes or cancer cells is differently affected by iron chelation with salicylaldehyde isonicotinoyl hydrazone. British journal of pharmacology 20080901
Clinical significance of minimal residual disease in patients with t(8;21) acute myeloid leukemia in Japan. International journal of hematology 20080901
Is ATP binding responsible for initiating drug translocation by the multidrug transporter ABCG2? The FEBS journal 20080901
Simultaneous determination of cyclophosphamide, ifosfamide, doxorubicin, epirubicin and daunorubicin in human urine using high-performance liquid chromatography/electrospray ionization tandem mass spectrometry: bioanalytical method validation. Rapid communications in mass spectrometry : RCM 20080901
Synergistic effect of the combination of nanoparticulate Fe3O4 and Au with daunomycin on K562/A02 cells. International journal of nanomedicine 20080901
Acyclovir bioavailability in patients with acute myelogenous leukemia treated with daunorubicin and cytarabine. Journal of clinical pharmacology 20080801
Flavonoids as inhibitors of human carbonyl reductase 1. Chemico-biological interactions 20080730
Deferiprone does not protect against chronic anthracycline cardiotoxicity in vivo. The Journal of pharmacology and experimental therapeutics 20080701
Inhibition of polymorphic human carbonyl reductase 1 (CBR1) by the cardioprotectant flavonoid 7-monohydroxyethyl rutoside (monoHER). Pharmaceutical research 20080701
Severe neurotoxicities in a case of Charcot-Marie-Tooth disease type 2 caused by vincristine for acute lymphoblastic leukemia. Journal of pediatric hematology/oncology 20080701
Two cases of post-liver transplant acute myeloid leukemia in Korean adults: review of bibliographies and comparison with post-renal transplant acute myeloid leukemia. Annals of hematology 20080601
Aldo-keto reductase 1C2 fails to metabolize doxorubicin and daunorubicin in vitro. Drug metabolism and disposition: the biological fate of chemicals 20080601
Structural elucidation of 4'-epiadriamycin by nuclear magnetic resonance spectroscopy and comparison with adriamycin and daunomycin using quantum mechanical and restrained molecular dynamics approach. Archives of biochemistry and biophysics 20080601
Results of the first randomized multicentre trial on childhood acute lymphoblastic leukaemia in Russia. Leukemia 20080601
Increase sensitivity to chemotherapeutical agents and cytoplasmatic interaction between NPM leukemic mutant and NF-kappaB in AML carrying NPM1 mutations. Leukemia 20080601
A rare case of co-existent aggressive natural killer cell and acute monocytic leukemia with cytomegalovirus infection. International journal of hematology 20080601
CE-LIF method for the separation of anthracyclines: application to protein binding analysis in plasma using ultrafiltration. Journal of separation science 20080601
CI-994 (N-acetyl-dinaline) in combination with conventional anti-cancer agents is effective against acute myeloid leukemia in vitro and in vivo. Oncology reports 20080601
[Effectiveness of the AML-XH-99-M3 protocol for treatment of acute promyelocytic leukemia in children]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20080601
Daunorubicin, cytarabine and fludarabine (DAF) for remission induction in relapsed or refractory acute myeloid leukemia. Evaluation of safety, tolerance and early outcome--Polish Adult Leukemia Group (PALG) pilot study. Annals of hematology 20080501
Two allelic variants of aldo-keto reductase 1A1 exhibit reduced in vitro metabolism of daunorubicin. Drug metabolism and disposition: the biological fate of chemicals 20080501
Mutated and non-mutated TP53 as targets in the treatment of leukaemia. British journal of haematology 20080501
Impact of column temperature and mobile phase components on selectivity of hydrophilic interaction chromatography (HILIC). Journal of separation science 20080501
Genetic variants contributing to daunorubicin-induced cytotoxicity. Cancer research 20080501
A phase II study of liposomal daunorubicin, in combination with cyclophosphamide, vincristine and prednisolone, in elderly patients with previously untreated aggressive non-Hodgkin lymphoma. Leukemia & lymphoma 20080501
A daidzein-daunomycin conjugate improves the therapeutic response in an animal model of ovarian carcinoma. The Journal of steroid biochemistry and molecular biology 20080501
Inhibiting wild-type and C299S mutant AKR1B10; a homologue of aldose reductase upregulated in cancers. European journal of pharmacology 20080428
Comparison of the results of the treatment of adolescents and young adults with standard-risk acute lymphoblastic leukemia with the Programa Español de Tratamiento en Hematología pediatric-based protocol ALL-96. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080410
Granulocytic sarcoma with massive scalp involvement. American journal of hematology 20080401
Potential of dendritic-cell immunotherapy for relapse after allogeneic hematopoietic stem cell transplantation, shown by WT1 peptide- and keyhole-limpet-hemocyanin-pulsed, donor-derived dendritic-cell vaccine for acute myeloid leukemia. American journal of hematology 20080401
MDR1 and BCRP1 expression in leukemic progenitors correlates with chemotherapy response in acute myeloid leukemia. Experimental hematology 20080401
Implications of sphingosine kinase 1 expression level for the cellular sphingolipid rheostat: relevance as a marker for daunorubicin sensitivity of leukemia cells. International journal of hematology 20080401
In vitro validation of gamma-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of T-cell acute lymphoblastic leukemia. Haematologica 20080401
Difficulty of peripheral blood stem cell collection after multiple consolidation therapy in acute myeloid leukemia. Journal of clinical and experimental hematopathology : JCEH 20080401
Outcomes of a modified CALGB 19802 regimen in adult acute lymphoblastic leukemia. Journal of Korean medical science 20080401
Novel nanocomposite of nano fe(3)o(4) and polylactide nanofibers for application in drug uptake and induction of cell death of leukemia cancer cells. Langmuir : the ACS journal of surfaces and colloids 20080304
Parotid acinar cell carcinoma in a long-term survivor of childhood acute lymphoblastic leukemia. Pediatric blood & cancer 20080301
Acute myelogenous leukemia associated with Ollier disease. Pediatric blood & cancer 20080301
Amsacrine containing induction therapy in elderly AML patients: comparison to standard induction regimens in a matched-pair analysis. Leukemia research 20080301
The prognostic significance of leukemic cells clearance kinetics evaluation during the initial course of induction therapy with HAD (homoharringtonine, cytosine arabinoside, daunorubicin) in patients with de novo acute myeloid leukemia. American journal of hematology 20080301
Iron chelation by clinically relevant anthracyclines: alteration in expression of iron-regulated genes and atypical changes in intracellular iron distribution and trafficking. Molecular pharmacology 20080301
The role of the proto-oncogene ETS2 in acute megakaryocytic leukemia biology and therapy. Leukemia 20080301
Abolition of stress-induced protein synthesis sensitizes leukemia cells to anthracycline-induced death. Blood 20080301
Clinical outcome of children with newly diagnosed acute lymphoblastic leukemia treated in a single center in Shanghai, China. Leukemia & lymphoma 20080301
Therapeutic experience of adult acute myeloid leukemia in a single institution of China and its relationship with chromosome karyotype. Leukemia & lymphoma 20080301
High-throughput screening for daunorubicin-mediated drug resistance identifies mometasone furoate as a novel ABCB1-reversal agent. Journal of biomolecular screening 20080301
Flurazepam inhibits the P-glycoprotein transport function: an insight to revert multidrug-resistance phenotype. European journal of pharmacology 20080226
The interaction of DNR and glutaraldehyde with cell membrane proteins leads to morphological changes in erythrocytes. Cancer letters 20080218
Images in haematology. Bilateral adrenal chloromas. British journal of haematology 20080201
Prominent cardioprotective effects of third generation beta blocker nebivolol against anthracycline-induced cardiotoxicity using the model of isolated perfused rat heart. European journal of cancer (Oxford, England : 1990) 20080201
Cardiomyopathy in children with Down syndrome treated for acute myeloid leukemia: a report from the Children's Oncology Group Study POG 9421. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080120
Long-term results of the AIEOP-ALL-95 Trial for Childhood Acute Lymphoblastic Leukemia: insight on the prognostic value of DNA index in the framework of Berlin-Frankfurt-Muenster based chemotherapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080110
The induction of apoptosis by daunorubicin and idarubicin in human trisomic and diabetic fibroblasts. Cellular & molecular biology letters 20080101
Thalidomide in induction treatment increases the very good partial response rate before and after high-dose therapy in previously untreated multiple myeloma. Haematologica 20080101
Pyridoxal isonicotinoyl hydrazone (PIH) and its analogs as protectants against anthracycline-induced cardiotoxicity. Hemoglobin 20080101
[Discrepant results of ABO type of red cells and serum in a patient with acute myelogenous leukemia]. [Rinsho ketsueki] The Japanese journal of clinical hematology 20080101
Assessment of febrile neutropenia episodes in children with acute leukemia treated with BFM protocols. Pediatric hematology and oncology 20080101
Clustering of endocytic organelles in parental and drug-resistant myeloid leukaemia cell lines lacking centrosomally organised microtubule arrays. The international journal of biochemistry & cell biology 20080101
Anticancer effects of Annona glabra plant extracts in human leukemia cell lines. Anticancer research 20080101
Relapse of acute myeloid leukemia as isolated bilateral testicular granulocytic sarcoma in an adult. Urology journal 20080101
Selective inhibition of yeast regulons by daunorubicin: a transcriptome-wide analysis. BMC genomics 20080101
[Anthracycline antibiotics and their derivatives--inhibitors of topoisomerase I]. Bioorganicheskaia khimiia 20080101
Effect of zinc and copper on the interaction of daunorubicin with cardiac myosin. Biological trace element research 20080101
[Efficacy of conservative treatment of gastric lymphosarcoma]. Terapevticheskii arkhiv 20080101
[Efficacy of therapy of different variants of anaplastic large T-cell lymphomas]. Terapevticheskii arkhiv 20080101
[Intensive chemotherapy of diffuse large B-cell lymphosarcoma in a female patient with chronic renal failure and afunctional left kidney]. Terapevticheskii arkhiv 20080101
Curative strategies in acute promyelocytic leukemia. Hematology. American Society of Hematology. Education Program 20080101
Reversal of drug resistance by silencing Survivin gene expression in acute myeloid leukemia cells. Acta biochimica Polonica 20080101
[Analysis of therapy results and prognostic factors in children with acute lymphoblastic leukaemia in Warmia and Mazury region: 17-years experience]. Medycyna wieku rozwojowego 20080101
[Lineage switch - conversion of acute lymphoblastic leukaemia to acute myeloid leukaemia in 4 years old girl]. Medycyna wieku rozwojowego 20080101
[Acute pancreatitis during chemotherapy of acute lymphoblastic leukaemia complicated with pseudocyst]. Medycyna wieku rozwojowego 20080101
Dissecting the component reactions catalyzed by the actinorhodin minimal polyketide synthase. Biochemistry 20071218
In vitro assessment of a novel polyrotaxane-based drug delivery system integrated with a cell-penetrating peptide. Journal of controlled release : official journal of the Controlled Release Society 20071204
Phase II evaluation of an intensified induction therapy with standard daunomycin and cytarabine followed by high dose cytarabine for adults with previously untreated acute myeloid leukemia: a Southwest Oncology Group study (SWOG-9500). American journal of hematology 20071201
Modulation of P-glycoprotein-mediated multidrug resistance by acceleration of passive drug permeation across the plasma membrane. The FEBS journal 20071201
Negative effect of DNA hypermethylation on the outcome of intensive chemotherapy in older patients with high-risk myelodysplastic syndromes and acute myeloid leukemia following myelodysplastic syndrome. Clinical cancer research : an official journal of the American Association for Cancer Research 20071201
Edaravone, a potent free radical scavenger, prevents anthracycline-induced myocardial cell death. Circulation journal : official journal of the Japanese Circulation Society 20071101
Incidence and outcome of TCF3-PBX1-positive acute lymphoblastic leukemia in Austrian children. Haematologica 20071101
The NQO1 C609T polymorphism is associated with risk of secondary malignant neoplasms after treatment for childhood acute lymphoblastic leukemia: a matched-pair analysis from the ALL-BFM study group. Haematologica 20071101
[A short duration treatment with intensive consolidation therapy for patients with acute myelogenous leukemia--13 year experience in a single institute]. Gan to kagaku ryoho. Cancer & chemotherapy 20071101
Predicting asparaginase-associated pancreatitis. Pediatric blood & cancer 20071015
Daunomycin binding to detergent micelles: a model system for evaluating the hydrophobic contribution to drug-DNA interactions. The journal of physical chemistry. B 20071004
Trisomy 21 as a sole acquired abnormality in an adult Omani patient with CD7- and CD9-positive acute myeloid leukemia. Archives of medical research 20071001
Genetic alterations determine chemotherapy resistance in childhood T-ALL: modelling in stage-specific cell lines and correlation with diagnostic patient samples. British journal of haematology 20071001
Higher plasma but not intracellular concentrations after infusion with liposomal daunorubicin compared with conventional daunorubicin in adult acute myeloid leukemia. Therapeutic drug monitoring 20071001
Reversal of P-glycoprotein-mediated multidrug resistance by cholesterol derived from low density lipoprotein in a vinblastine-resistant human lymphoblastic leukemia cell line. Biochemistry and cell biology = Biochimie et biologie cellulaire 20071001
Inhibitory effects of ginsenosides and their hydrolyzed metabolites on daunorubicin transport in KB-C2 cells. Biological & pharmaceutical bulletin 20071001
Increased resistance of tumor cells to daunorubicin after transfection of cDNAs coding for anthracycline inactivating enzymes. Cancer letters 20070918
AZD1152, a novel and selective aurora B kinase inhibitor, induces growth arrest, apoptosis, and sensitization for tubulin depolymerizing agent or topoisomerase II inhibitor in human acute leukemia cells in vitro and in vivo. Blood 20070915
Transition on the entropic elasticity of DNA induced by intercalating molecules. The Journal of chemical physics 20070914
All-trans retinoic acid syndrome: another cause of drug-induced respiratory failure. Southern medical journal 20070901
Liposomal daunorubicin as treatment for Kaposi's sarcoma. International journal of nanomedicine 20070901
Prognostic significance of WT1 gene expression in pediatric acute myeloid leukemia. Pediatric blood & cancer 20070801
On the origin of the decrease in stability of the DNA hairpin d(GCGAAGC) on complexation with aromatic drugs. Biophysical chemistry 20070801
Modeling of in vitro drug activity and prediction of clinical outcome in acute myeloid leukemia. Journal of clinical pharmacology 20070801
The criteria for bone marrow recovery post-myelosuppressive therapy for acute myelogenous leukemia: a quantitative study. Archives of pathology & laboratory medicine 20070801
In vitro and in vivo examination of cardiac troponins as biochemical markers of drug-induced cardiotoxicity. Toxicology 20070731
Analytical method for beta-amyloid fibrils using CE-laser induced fluorescence and its application to screening for inhibitors of beta-amyloid protein aggregation. Analytical chemistry 20070701
Topoisomerase IIalpha mRNA and protein expression vs. in vitro drug resistance and clinical outcome in acute leukaemia. International journal of oncology 20070701
Vincristine-induced acute neurotoxicity versus Guillain-Barré syndrome: a diagnostic dilemma. European journal of neurology 20070701
Inhibition of P-glycoprotein function by tannic acid and pentagalloylglucose. The Journal of pharmacy and pharmacology 20070701
Iron chelation-afforded cardioprotection against chronic anthracycline cardiotoxicity: a study of salicylaldehyde isonicotinoyl hydrazone (SIH). Toxicology 20070625
Postremission treatment of elderly patients with acute myeloid leukemia in first complete remission after intensive induction chemotherapy: results of the multicenter randomized Acute Leukemia French Association (ALFA) 9803 trial. Blood 20070615
Species differences of inhibitory effects on P-glycoprotein-mediated drug transport. Journal of pharmaceutical sciences 20070601
Improved immunocytochemical detection of daunomycin. Histochemistry and cell biology 20070601
Modulation of P-glycoprotein-mediated resistance by kaempferol derivatives isolated from Zingiber zerumbet. Phytotherapy research : PTR 20070601
A functional genetic polymorphism on human carbonyl reductase 1 (CBR1 V88I) impacts on catalytic activity and NADPH binding affinity. Drug metabolism and disposition: the biological fate of chemicals 20070601
Significance of persistent Auer rods and cytogenetic abnormality after first cycle of therapy for acute promyelocytic leukaemia. British journal of haematology 20070601
The quality of molecular response to chemotherapy is predictive for the outcome of AML1-ETO-positive AML and is independent of pretreatment risk factors. Leukemia 20070601
Mapping genes that contribute to daunorubicin-induced cytotoxicity. Cancer research 20070601
Outcome of adult acute lymphoblastic leukemia with BFM protocol in a resource-constrained setting. Leukemia & lymphoma 20070601
Evaluation of renal function in Turkish children receiving BFM-95 therapy for acute lymphoblastic leukemia. Pediatric hematology and oncology 20070601
Isolated granulocytic sarcoma of the orbit. European journal of haematology 20070501
Monitoring of minimal residual disease in adult acute myeloid leukemia using peripheral blood as an alternative source to bone marrow. Haematologica 20070501
[Effects of daunorubicin on the expression of brain natriuretic peptide gene in myocardial cells: an in vitro experiment with cultured myocardial cells from rats]. Zhonghua yi xue za zhi 20070424
Chemoinformatics analysis identifies cytotoxic compounds susceptible to chemoresistance mediated by glutathione and cystine/glutamate transport system xc-. Journal of medicinal chemistry 20070419
Mechanisms of ischemic stroke in HIV-infected patients. Neurology 20070417
Chemotherapy exposure increases leukemia cell stiffness. Blood 20070415
Synthesis of daunorubicin analogues containing truncated aromatic cores and unnatural monosaccharide residues. The Journal of organic chemistry 20070413
Traces of phosgene in chloroform: consequences for extraction of anthracyclines. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070401
Actin disruption inhibits endosomal traffic of P-glycoprotein-EGFP and resistance to daunorubicin accumulation. American journal of physiology. Cell physiology 20070401
Pharmacodynamics and safety of intravenous pegaspargase during remission induction in adults aged 55 years or younger with newly diagnosed acute lymphoblastic leukemia. Blood 20070401
Interactions of cyclosporin a with breast cancer resistance protein. Drug metabolism and disposition: the biological fate of chemicals 20070401
IkappaBalpha independent induction of NF-kappaB and its inhibition by DHMEQ in Hodgkin/Reed-Sternberg cells. Laboratory investigation; a journal of technical methods and pathology 20070401
Acute cardiac functional and morphological changes after Anthracycline infusions in children. The American journal of cardiology 20070401
Impact of FLT3 internal tandem duplications on Indian acute promyelocytic leukemia patients: prognostic implications. Hematology (Amsterdam, Netherlands) 20070401
Diffuse alveolar damage and hemorrhage in acute myelogenous leukemia treated with corticosteroids. Connecticut medicine 20070401
[Effect of daunorubicin and cytarabine on cell line NB4]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20070401
Relationship between in vitro chemosensitivity assessed with MTT assay and clinical outcomes in 103 patients with acute leukemia. The Korean journal of laboratory medicine 20070401
Anti-Cripto Mab inhibit tumour growth and overcome MDR in a human leukaemia MDR cell line by inhibition of Akt and activation of JNK/SAPK and bad death pathways. British journal of cancer 20070326
The application of Fe3O4 nanoparticles in cancer research: a new strategy to inhibit drug resistance. Journal of biomedical materials research. Part A 20070315
T-cell acute lymphoblastic leukemia relapsing as acute myelogenous leukemia. Pediatric blood & cancer 20070301
Adolescents with acute lymphoblastic leukaemia: outcome on UK national paediatric (ALL97) and adult (UKALLXII/E2993) trials. Pediatric blood & cancer 20070301
Improved outcome in childhood acute myeloid leukemia in Singapore with the MRC AML 10 protocol. Pediatric blood & cancer 20070301
Glucose uptake inhibitor sensitizes cancer cells to daunorubicin and overcomes drug resistance in hypoxia. Cancer chemotherapy and pharmacology 20070301
The enhancement effect of gold nanoparticles in drug delivery and as biomarkers of drug-resistant cancer cells. ChemMedChem 20070301
Effect of priming with granulocyte-macrophage colony-stimulating factor in younger adults with newly diagnosed acute myeloid leukemia: a trial by the Acute Leukemia French Association (ALFA) Group. Leukemia 20070301
Absence of prognostic impact of CD13 and/or CD33 antigen expression in adult acute lymphoblastic leukemia. Results of the GIMEMA ALL 0496 trial. Haematologica 20070301
Donor lymphocyte infusion for the treatment of leukemia relapse after HLA-mismatched/haploidentical T-cell-replete hematopoietic stem cell transplantation. Haematologica 20070301
Function-altering SNPs in the human multidrug transporter gene ABCB1 identified using a Saccharomyces-based assay. PLoS genetics 20070301
Almost normal cognitive function in patients during therapy for childhood acute lymphoblastic leukemia without cranial irradiation according to ALL-BFM 95 and COALL 06-97 protocols: results of an Austrian-German multicenter longitudinal study and implications for follow-up. Pediatric hematology and oncology 20070301
Schisandrin B: a dual inhibitor of P-glycoprotein and multidrug resistance-associated protein 1. Cancer letters 20070208
Pharmacological inhibition or small interfering RNA targeting acid ceramidase sensitizes hepatoma cells to chemotherapy and reduces tumor growth in vivo. Oncogene 20070208
Results of the PETHEMA ALL-96 trial in elderly patients with Philadelphia chromosome-negative acute lymphoblastic leukemia. European journal of haematology 20070201
Effects of topoisomerase II inhibitors on retinal pigment epithelium and experimental proliferative vitreoretinopathy. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20070201
Expression of multidrug resistance (MDR) proteins and in vitro drug resistance in acute leukemias. Hematology (Amsterdam, Netherlands) 20070201
Novel tetrahydroisoquinolin-ethyl-phenylamine based multidrug resistance inhibitors with broad-spectrum modulating properties. Cancer chemotherapy and pharmacology 20070101
Fate of 5-fluorouracil, doxorubicin, epirubicin, and daunorubicin in hospital wastewater and their elimination by activated sludge and treatment in a membrane-bio-reactor system. Chemosphere 20070101
Distribution of anticancer antibiotic daunomycin in the rat heart and kidney revealed by immunocytochemistry using monoclonal antibodies. Histochemistry and cell biology 20070101
Effects of Kaempferia parviflora extracts and their flavone constituents on P-glycoprotein function. Journal of pharmaceutical sciences 20070101
Involvement of caspase-8 in chemotherapy-induced apoptosis of patient derived leukemia cell lines independent of the death receptor pathway and downstream from mitochondria. Apoptosis : an international journal on programmed cell death 20070101
Epithelial-mesenchymal interactions in keloid pathogenesis modulate vascular endothelial growth factor expression and secretion. The Journal of pathology 20070101
Early detection of anthracycline cardiotoxicity in a rabbit model: left ventricle filling pattern versus troponin T determination. Physiological research 20070101
Modifying the sugar moieties of daunorubicin overcomes P-gp-mediated multidrug resistance. Molecular pharmaceutics 20070101
[The effect of rubomycin, mexidol and emoxypine on some metabolic indexes and the proccess of spontaneous metastasis under conditions of experimental neoplasia]. Eksperimental'naia i klinicheskaia farmakologiia 20070101
Biological properties of new derivatives of daunorubicin. In vivo (Athens, Greece) 20070101
LEDGF/p75 has increased expression in blasts from chemotherapy-resistant human acute myelogenic leukemia patients and protects leukemia cells from apoptosis in vitro. Molecular cancer 20070101
Selectivity of an indolyl berberine derivative for tetrameric G-quadruplex DNA. Rapid communications in mass spectrometry : RCM 20070101
Pre-apoptotic response to therapeutic DNA damage involves protein modulation of Mcl-1, Hdm2 and Flt3 in acute myeloid leukemia cells. Molecular cancer 20070101
Evaluation of ECG time intervals in a rabbit model of anthracycline-induced cardiomyopathy: a useful tool for assessment of cardioprotective agents. Physiological research 20070101
Daunorubicin-induced cell kill with 1-hour versus 24-hour infusions: a randomized comparison in children with newly diagnosed acute lymphoblastic leukemia. Klinische Padiatrie 20070101
[Modified BFM-90 regimen greatly improves treatment outcomes of chinese childhood and adolescent lymphoblastic lymphoma]. Zhonghua zhong liu za zhi [Chinese journal of oncology] 20070101
Vascular endothelium: target or victim of cytostatic therapy? Canadian journal of physiology and pharmacology 20070101
[Comparison of the present and previously used protocol of risk stratification in children with acute lymphoblastic leukemia]. Medycyna wieku rozwojowego 20070101
Coenzyme Q10 concentration in the plasma of children suffering from acute lymphoblastic leukaemia before and during induction treatment. BioFactors (Oxford, England) 20070101
Impact of hypoxic and acidic extracellular conditions on cytotoxicity of chemotherapeutic drugs. Advances in experimental medicine and biology 20070101
[The results of a multicenter trial of acute lymphoblastic leukemia treatment on ALL-MB 91/ALL-BFM 90m in children: analysis of efficacy and toxicity]. Terapevticheskii arkhiv 20070101
Anthracycline antibiotics induce acute renal tubular toxicity in children with cancer. Pathology oncology research : POR 20070101
Acute lymphoblastic leukemia in a patient with chronic cyanoacrylate exposure. Acta haematologica 20070101
Altered pharmacokinetics of daunorubicin in rats with CCl4-induced hepatic injury. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20070101
Neutropenic enterocolitis: is there a right timing for surgery? Assessment of a clinical case. Tumori 20070101
A comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) of anthranilamide derivatives that are multidrug resistance modulators. Journal of medicinal chemistry 20061228
Is cytarabine useful in the treatment of acute promyelocytic leukemia? Results of a randomized trial from the European Acute Promyelocytic Leukemia Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061220
Amrubicin induces apoptosis in human tumor cells mediated by the activation of caspase-3/7 preceding a loss of mitochondrial membrane potential. Cancer science 20061201
Cardioprotective effects of a novel iron chelator, pyridoxal 2-chlorobenzoyl hydrazone, in the rabbit model of daunorubicin-induced cardiotoxicity. The Journal of pharmacology and experimental therapeutics 20061201
Complexation of anthracycline drugs with DNA in the presence of caffeine. European biophysics journal : EBJ 20061201
Avascular necrosis--an antineoplastic-treatment-related toxicity: the experiences of two institutions. Pediatric hematology and oncology 20061201
Increased mortality with FLA compared with ADE chemotherapy in high-risk AML. Blood 20061201
Cardioprotective effects of subcutaneous ebselen against daunorubicin-induced cardiomyopathy in rats. Basic & clinical pharmacology & toxicology 20061201
seco-Cycloartane triterpenes from Gardenia aubryi. Journal of natural products 20061201
Childhood CD4+/CD56+ hematodermic neoplasm: case report and review of the literature. Haematologica 20061201
Favourable outcome in an APL patient with PLZF/RARalpha fusion gene: quantitative real-time RT-PCR confirms molecular response. Haematologica 20061201
[Combined effect of recombinant mutant human TRAIL and daunorubicin in inducing apoptosis of leukemia cell and its mechanism]. Zhongguo shi yan xue ye xue za zhi 20061201
Synergistic effects of troglitazone in combination with cytotoxic agents in acute myelogenous leukaemia cells. Leukemia research 20061101
Improved treatment outcome in Chinese children and adolescents with Burkitt's lymphoma and large cell lymphoma by using the modified B-non-Hodgkin's lymphoma-Berlin-Frankfurt-Münster-90 protocol. European journal of haematology 20061101
Multiple drugbinding sites on the R482G isoform of the ABCG2 transporter. British journal of pharmacology 20061101
Enhanced daunomycin accumulation in human intestinal Caco-2 cells from non-ionic food emulsifiers unrelated to the p-glycoprotein inhibitory mechanism. Bioscience, biotechnology, and biochemistry 20061101
Prevention of chronic anthracycline cardiotoxicity in the adult Fischer 344 rat by dexrazoxane and effects on iron metabolism. Cancer chemotherapy and pharmacology 20061001
Efficacy of liposomal daunorubicin and cytarabine as reinduction chemotherapy in relapsed acute lymphoblastic leukaemia despite expression of multidrug resistance-related proteins. European journal of haematology 20061001
CD36 (thrombospondin receptor) expression in childhood acute megakaryoblastic leukemia: in vitro drug sensitivity and outcome. Leukemia & lymphoma 20061001
Improvement of intestinal absorption of P-glycoprotein substrate by D-tartaric acid. Drug metabolism and pharmacokinetics 20061001
Less toxicity by optimizing chemotherapy, but not by addition of granulocyte colony-stimulating factor in children and adolescents with acute myeloid leukemia: results of AML-BFM 98. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060920
[Twenty years of treating childhood acute lymphoblastic leukemia]. Anales de pediatria (Barcelona, Spain : 2003) 20060901
AIDS-associated Burkitt or Burkitt-like lymphoma: short intensive polychemotherapy is feasible and effective. Leukemia & lymphoma 20060901
Treatment of Philadelphia-chromosome-positive acute lymphoblastic leukemia with imatinib in combination with chemotherapy. Current hematologic malignancy reports 20060901
Chemopotentiating effects of a novel NAD biosynthesis inhibitor, FK866, in combination with antineoplastic agents. European journal of medical research 20060830
Activating NOTCH1 mutations predict favorable early treatment response and long-term outcome in childhood precursor T-cell lymphoblastic leukemia. Blood 20060815
Combined Fourier transform infrared and Raman spectroscopic approach for identification of multidrug resistance phenotype in cancer cell lines. Biopolymers 20060805
Trisomy 19 as the sole chromosomal abnormality in proliferative chronic myelomonocytic leukemia. Leukemia research 20060801
Upregulation of secretory connective tissue growth factor (CTGF) in keratinocyte-fibroblast coculture contributes to keloid pathogenesis. Journal of cellular physiology 20060801
[Acute monoblastic leukemia with tetrasomy 8]. [Rinsho ketsueki] The Japanese journal of clinical hematology 20060801
In vitro and in vivo evaluation of WK-X-34, a novel inhibitor of P-glycoprotein and BCRP, using radio imaging techniques. International journal of cancer 20060715
Inhibition of the multidrug-resistant phenotype by targeting YB-1 with a conditionally oncolytic adenovirus: implications for combinatorial treatment regimen with chemotherapeutic agents. Cancer research 20060715
Dibenzocyclooctadiene lingnans: a class of novel inhibitors of P-glycoprotein. Cancer chemotherapy and pharmacology 20060701
9-O-acetyl GD3 protects tumor cells from apoptosis. International journal of cancer 20060701
Functional validation of the genetic polymorphisms of human ATP-binding cassette (ABC) transporter ABCG2: identification of alleles that are defective in porphyrin transport. Molecular pharmacology 20060701
Treatment of cavitary pulmonary zygomycosis with surgical resection and posaconazole. The Annals of thoracic surgery 20060701
Electrochemical detection and control of interactions between DNA and electroactive intercalator using a DNA-alginate complex film modified electrode. Environmental science & technology 20060701
Cyclohexylpiperazine derivative PB28, a sigma2 agonist and sigma1 antagonist receptor, inhibits cell growth, modulates P-glycoprotein, and synergizes with anthracyclines in breast cancer. Molecular cancer therapeutics 20060701
Ratiometric dosing of anticancer drug combinations: controlling drug ratios after systemic administration regulates therapeutic activity in tumor-bearing mice. Molecular cancer therapeutics 20060701
Imatinib activity in vitro in tumor cells from patients with chronic myeloid leukemia in chronic phase and blast crisis. Anti-cancer drugs 20060701
Effects of angiotensin II receptor blocker (candesartan) in daunorubicin-induced cardiomyopathic rats. International journal of cardiology 20060628
[Acute lymphoblastic leukaemia in Danish children and young people 10 to 19 years of age. Should young adults with acute lymphoblastic leukaemia be treated in the same way as children?]. Ugeskrift for laeger 20060626
Fludarabine and cytosine are less effective than standard ADE chemotherapy in high-risk acute myeloid leukemia, and addition of G-CSF and ATRA are not beneficial: results of the MRC AML-HR randomized trial. Blood 20060615
Correlation of the acid-sensitivity of polyethylene glycol daunorubicin conjugates with their in vitro antiproliferative activity. Bioorganic & medicinal chemistry 20060615
STI571 combined with vincristine greatly suppressed the tumor formation of multidrug-resistant K562 cells in a human-nude mice xenograft model. Chinese medical journal 20060605
Isochromosome 1q in a myelodysplastic syndrome after treatment for acute promyelocytic leukemia. Cancer genetics and cytogenetics 20060601
Heterologous expression of a mammalian ABC transporter in plant and its application to phytoremediation. Plant molecular biology 20060601
Extensive myelofibrosis responsive to treatment for acute erythroblastic leukaemia. The Malaysian journal of pathology 20060601
Innovative schedule of oral idarubicin in elderly patients with metastatic breast cancer: comprehensive results of a phase II multi-institutional study with pharmacokinetic drug monitoring. Annals of oncology : official journal of the European Society for Medical Oncology 20060501
Shifting to outpatient management of acute myeloid leukemia: a prospective experience. Annals of oncology : official journal of the European Society for Medical Oncology 20060501
Remission induction chemotherapy induces in vivo caspase-dependent apoptosis in bone marrow acute myeloid leukemia blast cells and spares lymphocytes. Cytometry. Part B, Clinical cytometry 20060501
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Changes in angiopoietin expression in glomeruli involved in glomerulosclerosis in rats with daunorubicin-induced nephrosis. Acta pharmacologica Sinica 20060501
Effect of amifostine on the cytotoxicity of daunorubicin and daunoxome in tumor and normal cells. Cancer chemotherapy and pharmacology 20060401
Investigation of genotoxic and antigenotoxic activities of Melampodium divaricatum in Salmonella typhimurium. Toxicology in vitro : an international journal published in association with BIBRA 20060401
Combination of tetrandrine as a potential-reversing agent with daunorubicin, etoposide and cytarabine for the treatment of refractory and relapsed acute myelogenous leukemia. Leukemia research 20060401
Pleural tumors as sole primary manifestation of acute promyelocytic leukemia. Annals of oncology : official journal of the European Society for Medical Oncology 20060401
Role of treatment intensification in infants with acute lymphoblastic leukemia: results of two consecutive AIEOP studies. Haematologica 20060401
[Alteration of expression of survivin in HL-60 cells treated with chemotherapeutic drugs]. Zhongguo shi yan xue ye xue za zhi 20060401
Syntheses and biological activities of 3'-azido disaccharide analogues of daunorubicin against drug-resistant leukemia. Journal of medicinal chemistry 20060309
Immune thrombocytopenia following successful treatment of cancer in children. Pediatric blood & cancer 20060301
ALK-positive plasmablastic B-cell lymphoma with the clathrin-ALK gene rearrangement. Pediatric blood & cancer 20060301
Effects of daunorubicin, mitomycin C, azathioprine and cyclosporin A on human retinal pigmented epithelial, corneal endothelial and conjunctival cell lines. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20060301
Human stem cell factor-antibody [anti-SCF] enhances chemotherapy cytotoxicity in human CD34+ resistant myeloid leukaemia cells. Leukemia research 20060301
Treatment for myeloid leukaemia of Down syndrome: population-based experience in the UK and results from the Medical Research Council AML 10 and AML 12 trials. British journal of haematology 20060301
Selection of non-P-glycoprotein mediated high-level etoposide resistant cell lines by adriamycin with P-gp inhibitors. International journal of oncology 20060301
Changes in hypercoagulability by asparaginase: a randomized study between two asparaginases. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20060301
Semisynthetic homoharringtonine induces apoptosis via inhibition of protein synthesis and triggers rapid myeloid cell leukemia-1 down-regulation in myeloid leukemia cells. Molecular cancer therapeutics 20060301
Discovery of a daunorubicin analogue that exhibits potent antitumor activity and overcomes P-gp-mediated drug resistance. Journal of medicinal chemistry 20060209
Protective effect of selected flavonoids on in vitro daunorubicin-induced cardiotoxicity. Phytotherapy research : PTR 20060201
Acute lymphoblastic leukemia in adolescents between 10 and 19 years of age in Denmark--secondary publication. Danish medical bulletin 20060201
Treatment of anthracycline extravasation in mice with dexrazoxane with or without DMSO and hydrocortisone. Cancer chemotherapy and pharmacology 20060101
Decreased numbers of CD4+ T lymphocytes in peripheral blood after treatment of childhood acute lymphoblastic leukemia. Leukemia research 20060101
Niemann-Pick C1 protein facilitates the efflux of the anticancer drug daunorubicin from cells according to a novel vesicle-mediated pathway. The Journal of pharmacology and experimental therapeutics 20060101
Structure of daunomycin complexed to d-TGATCA by two-dimensional nuclear magnetic resonance spectroscopy. European journal of medicinal chemistry 20060101
Effects of idarubicin and idarubicinol on rat coronary resistance and vasoconstrictor responsiveness of isolated aorta and mesentery. Anti-cancer drugs 20060101
Mitotic catastrophe results in cell death by caspase-dependent and caspase-independent mechanisms. Cell cycle (Georgetown, Tex.) 20060101
Concomitant hairy cell and acute myeloid leukemia. European journal of haematology 20060101
Granulocytic sarcoma of the gingiva with trisomy 21. American journal of hematology 20060101
Alteration of genomic responses to doxorubicin and prevention of MDR in breast cancer cells by a polymer excipient: pluronic P85. Molecular pharmaceutics 20060101
Efficient delivery of an antisense oligodeoxyribonucleotide formulated in folate receptor-targeted liposomes. Anticancer research 20060101
Differential regulation of NF-kappaB activation and function by topoisomerase II inhibitors. BMC cancer 20060101
[Interaction between aromatic antibiotics and vitamins: 1H NMR analysis of the heteroassociation of nicotinamide and anthracycline antitumor antibiotics]. Biofizika 20060101
Early prediction of therapy response in patients with acute myeloid leukemia by nucleosomal DNA fragments. BMC cancer 20060101
Effect of structural modifications of anthracyclines on the ability to overcome drug resistance of cancer cells. Anticancer research 20060101
[Acute lymphoblastic leukemia in children with initial leucocytosis above 50,000/mm3: summary of treatment results of Polish Pediatric Leukemia/Lymphoma Study Group]. Przeglad lekarski 20060101
Zygomycosis in the immunocompromised patient: a case report. Acta bio-medica : Atenei Parmensis 20060101
Successful management of cerebral and pulmonary mucormycosis with liposomal amphotericin B in a 28-year-old woman with acute lymphoblastic leukemia. Acta bio-medica : Atenei Parmensis 20060101
A potential pathological role of angiopoietins expression in glomeruli during progressive glomerulisclerosis related to podocyte injury. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20060101
Reactions with dye free radicals reveal weak redox properties of drugs. Photochemistry and photobiology 20060101
Autoimmune hemolytic anemia as presenting manifestation of primary splenic anaplastic large cell lymphoma. The Turkish journal of pediatrics 20060101
[Reults of treatment with protocols BFM 90 and BFM 95]. Medicinski arhiv 20060101
[Auditory evoked potentials in patients after acute children's lymphoblastic leukemia treatment]. Przeglad lekarski 20060101
A new bisintercalating anthracycline with picomolar DNA binding affinity. Journal of medicinal chemistry 20051229
A randomized, postremission comparison of four courses of standard-dose consolidation therapy without maintenance therapy versus three courses of standard-dose consolidation with maintenance therapy in adults with acute myeloid leukemia: the Japan Adult Leukemia Study Group AML 97 Study. Cancer 20051215
Multilayer microcapsules as anti-cancer drug delivery vehicle: deposition, Sustained release, and in vitro bioactivity. Macromolecular bioscience 20051215
Evaluation of the immortalized human brain capillary endothelial cell line BB19 as a human cell culture model for the blood-brain barrier. Brain research 20051207
Endogenous thioredoxin is required for redox cycling of anthracyclines and p53-dependent apoptosis in cancer cells. The Journal of biological chemistry 20051202
Syntheses and biological activities of daunorubicin analogs with uncommon sugars. Bioorganic & medicinal chemistry 20051201
Transepithelial transport of fluorescent p-glycoprotein and MRP2 substrates by insect Malpighian tubules: confocal microscopic analysis of secreted fluid droplets. The Journal of experimental biology 20051201
p16 inactivation associated with aggressive clinical course and fatal outcome in TEL/AML1-positive acute lymphoblastic leukemia. Journal of pediatric hematology/oncology 20051201
Acute leukaemia presenting as vulvar ulcers in an adolescent girl. The Australian & New Zealand journal of obstetrics & gynaecology 20051201
Idarubicin and idarubicinol effects on breast cancer multicellular spheroids. Journal of chemotherapy (Florence, Italy) 20051201
Prediction of doxorubicin sensitivity in breast tumors based on gene expression profiles of drug-resistant cell lines correlates with patient survival. Oncogene 20051117
Anaplastic large cell lymphoma treated with a leukemia-like therapy: report of the Italian Association of Pediatric Hematology and Oncology (AIEOP) LNH-92 protocol. Cancer 20051115
Modulation of MDR1 gene expression in multidrug resistant MCF7 cells by low concentrations of small interfering RNAs. Biochemical pharmacology 20051115
Hematopoietic cells from Gadd45a- and Gadd45b-deficient mice are sensitized to genotoxic-stress-induced apoptosis. Oncogene 20051103
Long-term serial echocardiographic examination of late anthracycline cardiotoxicity and its prevention by dexrazoxane in paediatric patients. European journal of pediatrics 20051101
Herpes simplex virus pneumonia during standard induction chemotherapy for acute leukemia: case report and review of literature. Leukemia 20051101
Characterization of cells with different mitochondrial membrane potential during apoptosis. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20051101
Treatment of older patients with AML. Critical reviews in oncology/hematology 20051101
Mass spectrometry-based screening for inhibitors of beta-amyloid protein aggregation. Analytical chemistry 20051101
Apoptosis of bovine ovarian surface epithelial cells by Fas antigen/Fas ligand signaling. Reproduction (Cambridge, England) 20051101
Post-transplantation lymphoproliferative disorder of recipient origin in a boy with acute T-cell leukemia with detection of B-cell clonality 3 months before stem cell transplantation. Haematologica 20051101
Membranous glomerulopathy in children given allogeneic hematopoietic stem cell transplantation. Haematologica 20051101
The value of the MDR1 reversal agent PSC-833 in addition to daunorubicin and cytarabine in the treatment of elderly patients with previously untreated acute myeloid leukemia (AML), in relation to MDR1 status at diagnosis. Blood 20051015
Effects of alkyl gallates on P-glycoprotein function. Biochemical pharmacology 20051015
Chemotherapy dosing with elevated liver function test results in acute leukemia. The Annals of pharmacotherapy 20051001
Effects of new 4-aryl-1,4-dihydropyridines and 4-arylpyridines on drug efflux mediated by multidrug resistance-associated protein 1. Journal of pharmaceutical sciences 20051001
Rapid collapse of mitochondrial transmembrane potential in HL-60 cells and isolated mitochondria treated with anti-tumor 1,4-anthracenediones. Anti-cancer drugs 20051001
Influence of initial charge state on fragmentation patterns for noncovalent drug/DNA duplex complexes. Journal of mass spectrometry : JMS 20051001
Inhibition study of rabbit liver cytosolic reductases involved in daunorubicin toxication. Journal of enzyme inhibition and medicinal chemistry 20051001
Effect of nonylphenol ethoxylates (NPEs) on barrier functions of epithelial cell membranes: opening of tight junctions and competitive inhibition of P-gp-mediated efflux. International journal of pharmaceutics 20050930
Schisandrin B--a novel inhibitor of P-glycoprotein. Biochemical and biophysical research communications 20050923
Interaction of daunomycin antibiotic with human serum albumin: investigation by resonant mirror biosensor technique, fluorescence spectroscopy and molecular modeling methods. Journal of pharmaceutical and biomedical analysis 20050915
Engineered biosynthesis of aklanonic acid analogues. Journal of the American Chemical Society 20050907
Inhibition of thioredoxin reductase but not of glutathione reductase by the major classes of alkylating and platinum-containing anticancer compounds. Free radical biology & medicine 20050901
4-Demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin (PNU-159548): a promising new candidate for chemotherapeutic treatment of osteosarcoma patients. European journal of cancer (Oxford, England : 1990) 20050901
Treatment reduction in highly selected standard-risk childhood acute lymphoblastic leukemia. The AIEOP ALL-9501 study. Haematologica 20050901
Could Candida dubliniensis be involved in lung fungus balls? Revista iberoamericana de micologia 20050901
Prognostic factors and outcome of core binding factor acute myeloid leukemia patients with t(8;21) differ from those of patients with inv(16): a Cancer and Leukemia Group B study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050820
Syntheses and biological activities of disaccharide daunorubicins. Journal of medicinal chemistry 20050811
Ifosfamide/liposomal daunorubicin is a well tolerated and active first-line chemotherapy regimen in advanced soft tissue sarcoma: results of a phase II study. Cancer 20050801
[Transfection of HL-60 cells with CYP3A5 gene induces drug-resistant phenotype]. Zhonghua zhong liu za zhi [Chinese journal of oncology] 20050801
DNA electrochemistry through the base pairs not the sugar-phosphate backbone. Journal of the American Chemical Society 20050727
Effects of peroxidase substrates on the Amplex red/peroxidase assay: antioxidant properties of anthracyclines. Analytical biochemistry 20050715
Inactivation of anthracyclines by cellular peroxidase. Cancer research 20050715
In vitro activity of imatinib in cells from patients with adult acute lymphoblastic leukemia. Anti-cancer drugs 20050701
Acute promyelocytic leukemia after living donor partial orthotopic liver transplantation in two Japanese girls. Leukemia & lymphoma 20050701
Inhibition of P-glycoprotein by natural products in human breast cancer cells. Archives of pharmacal research 20050701
Reversion of human Pgp-dependent multidrug resistance by new sesquiterpenes from Zinowiewia costaricensis. Journal of medicinal chemistry 20050630
Reversal of MDR1 gene-dependent multidrug resistance using short hairpin RNA expression vectors. Chinese medical journal 20050605
Hematological and molecular remission with combination chemotherapy in a patient with PLZF-RARalpha acute promyelocytic leukemia (APML). Annals of hematology 20050601
High dose intermittent ARA-C (HiDAC) for consolidation of patients with de novo AML: a single center experience. Leukemia research 20050601
[Inhibitory effect of daunorubicin enhanced by PDTC on drug-resistant leukemic cells in vitro]. Zhongguo shi yan xue ye xue za zhi 20050601
The use of liposomal daunorubicin (DaunoXome) in acute myeloid leukemia. Leukemia & lymphoma 20050601
Evaluation of cytotoxicity by flow cytometric drug sensitivity assay in childhood T-cell acute lymphoblastic leukemia. Leukemia & lymphoma 20050601
[Reversal of multidrug resistance of HL-60 adriamycin resistant leukemia cell line by quercetin and its mechanisms]. Zhonghua zhong liu za zhi [Chinese journal of oncology] 20050601
Targeting of daunomycin using biotinylated immunoliposomes: pharmacokinetics, tissue distribution and in vitro pharmacological effects. Journal of drug targeting 20050601
Disease biology rather than age is the most important determinant of survival of patients > or = 60 years with acute myeloid leukemia treated with uniform intensive therapy. Cancer 20050515
Dexrazoxane protects against myelosuppression from the DNA cleavage-enhancing drugs etoposide and daunorubicin but not doxorubicin. Clinical cancer research : an official journal of the American Association for Cancer Research 20050515
Improved synthesis of daunomycin conjugates with triplex-forming oligonucleotides. The polypurine tract of HIV-1 as a target. Bioorganic & medicinal chemistry 20050502
One versus two high-dose cytarabine-based consolidation before autologous stem cell transplantation for young acute myeloblastic leukaemia patients in first complete remission. British journal of haematology 20050501
Precursor B-cell lymphoblastic lymphoma presenting as an isolated external ear swelling in a two-year-old child. International journal of pediatric otorhinolaryngology 20050501
Immunodeficiency in children with acute lymphoblastic leukemia after completion of modern aggressive chemotherapeutic regimens. The Journal of pediatrics 20050501
Limited value of FLT3 mRNA expression in the bone marrow for prognosis and monitoring of patients with acute myeloid leukemia. Haematologica 20050501
Trimers of N-alkylglycines are potent modulators of the multidrug resistance phenotype. The Journal of pharmacology and experimental therapeutics 20050401
Significant reduction of the hybrid BCR/ABL transcripts after induction and consolidation therapy is a powerful predictor of treatment response in adult Philadelphia-positive acute lymphoblastic leukemia. Leukemia 20050401
Effects of miltefosine on membrane permeability and accumulation of [99mTc]-hexakis-2-methoxyisobutyl isonitrile, 2-[18F]fluoro-2-deoxy-D-glucose, daunorubucin and rhodamine123 in multidrug-resistant and sensitive cells. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050401
Early response to induction is predictive of survival in childhood Philadelphia chromosome positive acute lymphoblastic leukaemia: results of the Medical Research Council ALL 97 trial. British journal of haematology 20050401
Immunocytochemistry for drugs containing an aliphatic primary amino group in the molecule, anticancer antibiotic daunomycin as a model. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20050401
Identification of genes associated with chemotherapy crossresistance and treatment response in childhood acute lymphoblastic leukemia. Cancer cell 20050401
[Influence of cytochrome C on apoptosis induced by daunorubicine in acute myeloid leukemia (AML) cells]. Zhongguo shi yan xue ye xue za zhi 20050401
Effects of daunorubicin and CD95L on retinal function in superfused vertebrate retina. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20050401
Control of P-glycoprotein activity by membrane cholesterol amounts and their relation to multidrug resistance in human CEM leukemia cells. Biochemistry 20050322
New 4-aryl-1,4-dihydropyridines and 4-arylpyridines as P-glycoprotein inhibitors. Drug metabolism and disposition: the biological fate of chemicals 20050301
Acute myeloid leukemia in the elderly: etoposide when anthracyclins are contraindicated. Leukemia & lymphoma 20050301
Study of daunorubicin cardiotoxicity prevention with pyridoxal isonicotinoyl hydrazone in rabbits. Pharmacological research 20050301
Prediction of individual response to chemotherapy in patients with acute myeloid leukaemia using the chemosensitivity index Ci. British journal of haematology 20050301
Toxicity of the topoisomerase II inhibitors. Expert opinion on drug safety 20050301
Human herpesvirus-8-related Kaposi's sarcoma after liver transplantation successfully treated with cidofovir and liposomal daunorubicin. Transplant infectious disease : an official journal of the Transplantation Society 20050301
The Gly-Arg-rich C-terminal domain of pea nucleolin is a DNA helicase that catalytically translocates in the 5'- to 3'-direction. Archives of biochemistry and biophysics 20050215
Comparison of two regimens for the treatment of elderly patients with acute lymphoblastic leukaemia (ALL). Leukemia & lymphoma 20050201
Outcome of induction and postremission therapy in younger adults with acute myeloid leukemia with normal karyotype: a cancer and leukemia group B study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050120
Synthesis and radioiodination of some daunorubicin and doxorubicin derivatives. Carbohydrate research 20050117
[Treatment results with ALL-BFM-95 protocol in children with acute lymphoblastic leukemia in Hungary]. Orvosi hetilap 20050109
Interaction between cardiac calsequestrin and drugs with known cardiotoxicity. Molecular pharmacology 20050101
Molecular mechanisms and kinetics between DNA and DNA binding ligands. Biophysical journal 20050101
Induction chemotherapy for acute myelogenous leukemia. Current hematology reports 20050101
The antitumor anthracyclines doxorubicin and daunorubicin do not inhibit cell growth through the formation of iron-mediated reactive oxygen species. Anti-cancer drugs 20050101
Intensified induction chemotherapy in adult acute myeloid leukemia followed by high-dose chemotherapy and autologous peripheral blood stem cell transplantation: an Eastern Cooperative Oncology Group trial (E4995). Leukemia & lymphoma 20050101
[Acute myelomonocytic leukemia complicated with multiple lower intestinal ulcers induced by nonsteroidal anti-inflammatory drugs]. Gan to kagaku ryoho. Cancer & chemotherapy 20050101
Hypoxia-induced acidification causes mitoxantrone resistance not mediated by drug transporters in human breast cancer cells. Cellular oncology : the official journal of the International Society for Cellular Oncology 20050101
In vivo antitumor activity of folate receptor-targeted liposomal daunorubicin in a murine leukemia model. Anticancer research 20050101
Outcome of acute myeloid leukaemia in adults: a retrospective analysis. The National medical journal of India 20050101
Flow cytometric monitoring of fluorescent drug retention and efflux. Methods in molecular medicine 20050101
Determination of caspase-3 activation fails to predict chemosensitivity in primary acute myeloid leukemia blasts. BMC cancer 20050101
Methylxanthines (caffeine, pentoxifylline and theophylline) decrease the mutagenic effect of daunomycin, doxorubicin and mitoxantrone. Acta biochimica Polonica 20050101
[Treatment of adult Berkitt-like lymphoma]. Terapevticheskii arkhiv 20050101
Chemotherapy for acute myeloid leukemias with cytosine arabinoside, daunorubicin, etoposide, and mitoxantrone may cause permanent oligoasthenozoospermia or amenorrhea in middle-aged patients. Neoplasma 20050101
Acute myeloid leukemia treatment in patients over 60 years of age. Comparison of symptomatic, palliative, and aggressive therapy. Neoplasma 20050101
Influence of the structure of new anthracycline antibiotics on their biological properties. Anticancer research 20050101
Anthracyclines, proteasome activity and multi-drug-resistance. BMC cancer 20050101
Usefulness of PKH fluorescent labelling to study leukemic cell proliferation with various cytostatic drugs or acetyl tetrapeptide--AcSDKP. BMC cancer 20050101
Prognostic impact of age in children and adolescents with acute lymphoblastic leukemia: data from the trials ALL-BFM 86, 90, and 95. Klinische Padiatrie 20050101
Cytotoxicity, cellular uptake and DNA damage by daunorubicin and its new analogues with modified daunosamine moiety. Cell biology and toxicology 20050101
Atypical pyoderma gangrenosum as a manifestation of childhood acute lymphoblastic leukemia. Pediatric dermatology 20050101
Reduction of 13-deoxydoxorubicin and daunorubicinol anthraquinones by human carbonyl reductase. Cardiovascular toxicology 20050101
6-mercaptopurine and daunorubicin double drug liposomes-preparation, drug-drug interaction and characterization. Journal of liposome research 20050101
Control of acute myeloid leukemia morbidity in northwest Iran. Asian Pacific journal of cancer prevention : APJCP 20050101
Synergistic effect of SU11248 with cytarabine or daunorubicin on FLT3 ITD-positive leukemic cells. Blood 20041215
Unusual sites of metastatic malignancy: case 3. Acute leukemia presenting as bilateral proptosis. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20041215
Relation between the ability of some compounds to modulate the MRP1-mediated efflux of glutathione and to inhibit the MRPl-mediated efflux of daunorubicin. Biochemical pharmacology 20041201
An extra X chromosome as a sole abnormality in relapse of an adult acute lymphoblastic leukemia. Cancer genetics and cytogenetics 20041201
Breast cancer resistance protein and P-glycoprotein in 149 adult acute myeloid leukemias. Clinical cancer research : an official journal of the American Association for Cancer Research 20041201
[Restorative effect of quercetin on subcellular distribution of daunorubicin in multidrug resistant leukemia cell lines K562/ADM and HL-60/ADM]. Ai zheng = Aizheng = Chinese journal of cancer 20041201
[Inducing effect of cyclosporin A on apoptosis of multidrug resistant cell lines HR20 and HT9]. Ai zheng = Aizheng = Chinese journal of cancer 20041201
[Efficacy of modified BFM-90 regimen on children and adolescents with T cell lymphoblastic lymphoma: a report of 20 cases]. Ai zheng = Aizheng = Chinese journal of cancer 20041201
Role of liposomal daunorubicin, fludarabine and cytarabine (FLAD) in the salvage therapy of adult acute lymphoblastic leukemia. Leukemia & lymphoma 20041201
Use of liposomal anthracyclines in Kaposi's sarcoma. Seminars in oncology 20041201
Role of liposomal anthracyclines in the treatment of multiple myeloma. Seminars in oncology 20041201
Cardiac safety of liposomal anthracyclines. Seminars in oncology 20041201
Pharmacoeconomics of liposomal anthracycline therapy. Seminars in oncology 20041201
Better outcome of adult acute lymphoblastic leukemia after early genoidentical allogeneic bone marrow transplantation (BMT) than after late high-dose therapy and autologous BMT: a GOELAMS trial. Blood 20041115
Combination of liposomal daunorubicin (DaunoXome), fludarabine, and cytarabine (FLAD) in patients with poor-risk acute leukemia. Annals of hematology 20041101
Teaching cases from the Royal Marsden and St Mary's Hospitals case 28: a patient with acute leukemia with rare leukemic cells of unusual morphology. Leukemia & lymphoma 20041101
Dose escalation studies of cytarabine, daunorubicin, and etoposide with and without multidrug resistance modulation with PSC-833 in untreated adults with acute myeloid leukemia younger than 60 years: final induction results of Cancer and Leukemia Group B Study 9621. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20041101
Antitumor triptycene bisquinones induce a caspase-independent release of mitochondrial cytochrome c and a caspase-2-mediated activation of initiator caspase-8 and -9 in HL-60 cells by a mechanism which does not involve Fas signaling. Anti-cancer drugs 20041101
An in vitro study on the mechanisms of coagulation activation in acute myelogenous leukemia (AML): role of tissue factor regulation by cytotoxic drugs and GM-CSF. Thrombosis and haemostasis 20041101
[Pharmacological adjuvants for surgical treatment of proliferative vitreoretinopathy]. Journal francais d'ophtalmologie 20041101
[Primary study of relationship between serum level of VEGF and non-Hodgkin's lymphoma in children and adolescent patients]. Ai zheng = Aizheng = Chinese journal of cancer 20041101
[Infection control in neutropenia induced by high-dose cytarabine chemotherapy]. Gan to kagaku ryoho. Cancer & chemotherapy 20041101
Inhibitory effect of a bitter melon extract on the P-glycoprotein activity in intestinal Caco-2 cells. British journal of pharmacology 20041001
Celastraceae sesquiterpenes as a new class of modulators that bind specifically to human P-glycoprotein and reverse cellular multidrug resistance. Cancer research 20041001
Testicular granulocytic sarcoma, a source of diagnostic confusion. Urology 20041001
Blanchaquinone: a new anthraquinone from an Australian Streptomyces sp. Journal of natural products 20041001
[Results of treatment of children with acute lymphoblastic leukemia with a modified BFM protocol]. Srpski arhiv za celokupno lekarstvo 20041001
A thoracic-epidural granulocytic sarcoma case that was diagnosed preceding the onset of and that recurred co-incidental to acute promyelocytic leukemia, which developed after surgical treatment. Acta medica Okayama 20041001
Antigenotoxic and antioxidant effect of grapefruit juice in mice treated with daunorubicin. Toxicology letters 20040925
Crystal structure of a ternary complex of DnrK, a methyltransferase in daunorubicin biosynthesis, with bound products. The Journal of biological chemistry 20040924
A mass spectrometric investigation of non-covalent interactions between ruthenium complexes and DNA. Dalton transactions (Cambridge, England : 2003) 20040907
Resistance to purine and pyrimidine nucleoside and nucleobase analogs by the human MDR1 transfected murine leukemia cell line L1210/VMDRC.06. Biochemical pharmacology 20040901
Sequence selective binding of bis-daunorubicin WP631 to DNA. European journal of biochemistry 20040901
Direct assessment of drug penetration into tissue using a novel application of three-dimensional cell culture. Cancer research 20040901
Treating childhood acute myeloid leukaemia with the AML-BFM-83 protocol: experience in a developing country. British journal of haematology 20040901
Thiol oxidation induced by oxidative action of adriamycin. Free radical research 20040901
ydaG and ydbA of Lactococcus lactis encode a heterodimeric ATP-binding cassette-type multidrug transporter. The Journal of biological chemistry 20040813
Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment. The New England journal of medicine 20040805
Increasing dose intensity of anthracycline antibiotics improves outcome in patients with acute myelogenous leukemia. American journal of hematology 20040801
Inhibition of P-glycoprotein function by tea catechins in KB-C2 cells. The Journal of pharmacy and pharmacology 20040801
Reversal of P-glycoprotein-mediated MDR by 5,7,3',4',5'-pentamethoxyflavone and SAR. Biochemical and biophysical research communications 20040730
Mechanisms of cross-resistance between nucleoside analogues and vincristine or daunorubicin in leukemic cells. Biochemical and biophysical research communications 20040730
Fatal hemorrhagic pneumonia caused by infection due to Kytococcus sedentarius--a pathogen or passenger? Annals of hematology 20040701
Acetaminophen stimulates the peroxidative metabolism of anthracyclines. Archives of biochemistry and biophysics 20040701
DNA intercalators differentially affect chromatin structure and DNA replication in Xenopus egg extract. Anti-cancer drugs 20040701
Treatment of children with B-cell non-Hodgkin's lymphoma in developing countries: the experience of a single center in Brazil. Journal of pediatric hematology/oncology 20040701
Sweet's syndrome associated with sargramostim (granulocyte-macrophage colony stimulating factor) treatment. American journal of hematology 20040701
Clinical effects and P-glycoprotein inhibition in patients with acute myeloid leukemia treated with zosuquidar trihydrochloride, daunorubicin and cytarabine. Haematologica 20040701
Chemotherapy-induced leukonychia. Haematologica 20040701
A novel effective and safe consolidation for patients over 60 years with acute myeloid leukemia: intermediate dose cytarabine (2 x 1 g/m2 on days 1, 3, and 5). Clinical cancer research : an official journal of the American Association for Cancer Research 20040615
Risk-adapted induction and consolidation therapy in adults with de novo AML aged </= 60 years: results of a prospective multicenter trial. Annals of hematology 20040601
A G-quadruplex-interactive agent, telomestatin (SOT-095), induces telomere shortening with apoptosis and enhances chemosensitivity in acute myeloid leukemia. International journal of oncology 20040601
Rabbit model for in vivo study of anthracycline-induced heart failure and for the evaluation of protective agents. European journal of heart failure 20040601
Multidrug resistance-1 (MDR-1) in autoimmune disorders IV. P-glycoprotein overfunction in lymphocytes from myasthenia gravis patients. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20040601
Priming with granulocyte colony-stimulating factor--relation to high-dose cytarabine in acute myeloid leukemia. The New England journal of medicine 20040520
Addition of cladribine to daunorubicin and cytarabine increases complete remission rate after a single course of induction treatment in acute myeloid leukemia. Multicenter, phase III study. Leukemia 20040501
Co-existence of Philadelphia chromosome positive acute megakaryoblastic and B-lymphoblastic mixed blast crisis of chronic myeloid leukemia with chronic lymphocytic leukemia. European journal of haematology 20040501
Broad-spectrum modulation of ATP-binding cassette transport proteins by the taxane derivatives ortataxel (IDN-5109, BAY 59-8862) and tRA96023. Cancer chemotherapy and pharmacology 20040501
Drastic effect of cell density on the cytotoxicity of daunorubicin and cytosine arabinoside. Biochemical pharmacology 20040501
Prognostic impact of early response to induction therapy as assessed by multiparameter flow cytometry in acute myeloid leukemia. Haematologica 20040501
Ceramide : A New Target in Anticancer Research? Bulletin du cancer 20040501
Cytoprotective effect of glucosylceramide synthase inhibition against daunorubicin-induced apoptosis in human leukemic cell lines. The Journal of biological chemistry 20040430
Folate concentration dependent transport activity of the Multidrug Resistance Protein 1 (ABCC1). Biochemical pharmacology 20040415
Outcome of childhood acute promyelocytic leukemia with all-trans-retinoic acid and chemotherapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040415
Biphasic acute myeloid leukemia with near-tetraploidy and immunophenotypic transformation. Archives of pathology & laboratory medicine 20040401
N-terminal tail domains of core histones in nucleosome block the access of anticancer drugs, mithramycin and daunomycin, to the nucleosomal DNA. Biophysical chemistry 20040401
Tailored therapy of adult acute leukaemia in Jehovah's Witnesses: unjustified reluctance to treat. European journal of haematology 20040401
[Study on the relationship between [Ca2+]i and the MDR formation in K562/A02 cells]. Zhongguo shi yan xue ye xue za zhi 20040401
[Preliminary study of DA or HA regimen chemotherapy for the treatment of refractory and relapsed paroxysmal nocturnal hemoglobinuria]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20040401
Pharmacokinetic comparison of 120-hour infusion versus hyperfractionated oral administration of idarubicin. Journal of chemotherapy (Florence, Italy) 20040401
The analysis of correlations between drug resistance and clinical/laboratory measures found in a group of children with all treated by ALL-BFM 90 protocol. Bulletin du cancer 20040401
Dynamic and intracellular trafficking of P-glycoprotein-EGFP fusion protein: Implications in multidrug resistance in cancer. International journal of cancer 20040320
Relationship between daunorubicin concentration and apoptosis induction in leukemic cells. Biochemical pharmacology 20040315
Studies on pyrrolopyrimidines as selective inhibitors of multidrug-resistance-associated protein in multidrug resistance. Journal of medicinal chemistry 20040311
P-glycoprotein inhibitors modulate accumulation and efflux of xenobiotics in extra and intracellular Toxoplasma gondii. Molecular and biochemical parasitology 20040301
Granulocytic sarcoma of the testis. Urology 20040301
[Acute promyelocytic leukemia after living donor partial orthotopic liver transplantation]. [Rinsho ketsueki] The Japanese journal of clinical hematology 20040301
[Effect of ATRA and DNR on the expression and secretion of VEGF in leukemic cells]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20040301
Resveratrol inhibits drug-induced apoptosis in human leukemia cells by creating an intracellular milieu nonpermissive for death execution. Cancer research 20040215
Jatrophane diterpenes as modulators of multidrug resistance. Advances of structure-activity relationships and discovery of the potent lead pepluanin A. Journal of medicinal chemistry 20040212
Caspase-dependent apoptosis and -independent poly(ADP-ribose) polymerase cleavage induced by transforming growth factor beta1. The international journal of biochemistry & cell biology 20040201
Simple, semiautomatic assay of cytostatic and cytotoxic effects of antitumor drugs by laser scanning cytometry: effects of the bis-intercalator WP631 on growth and cell cycle of T-24 cells. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20040201
Does anthracycline administration by infusion in children affect late cardiotoxicity? British journal of haematology 20040201
Biodistribution study of doxorubicin encapsulated in liposomes: influence of peptide coating and lipid composition. Preparative biochemistry & biotechnology 20040201
Fluorescent modified phosphatidylcholine floppase activity of reconstituted multidrug resistance-associated protein MRP1. Biochimica et biophysica acta 20040128
Evidence that activation of nuclear factor-kappaB is essential for the cytotoxic effects of doxorubicin and its analogues. Biochemical pharmacology 20040115
Prognostic relevance of immunophenotyping in 379 patients with acute myeloid leukemia. Leukemia research 20040101
Pilot study of idarubicin-based intensive-timing induction therapy for children with previously untreated acute myeloid leukemia: Children's Cancer Group Study 2941. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040101
Uncommon presentations of Hodgkin's disease. Case 2. Hodgkin's disease of the nasopharynx. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040101
Synthesis of a library of 3-oxopiperazinium and perhydro-3-oxo-1,4-diazepinium derivatives and identification of bioactive compounds. Journal of combinatorial chemistry 20040101
Myocardial ischemia in a patient with acute lymphoblastic leukemia during L-asparaginase therapy. European journal of haematology 20040101
Proteomic signatures for daunomycin and adriamycin in Bacillus subtilis. Die Pharmazie 20040101
Antiproliferative efficacy of the third-generation bisphosphonate, zoledronic acid, combined with other anticancer drugs in leukemic cell lines. International journal of hematology 20040101
Second-line chemotherapy with the association of liposomal daunorubicin, carboplatin and etoposide in children with recurrent malignant brain tumors. Journal of neuro-oncology 20040101
P-glycoprotein (Pgp) modulation in untreated acute myeloid leukemia (AML): Cancer and Leukemia Group B (CALGB) trials in younger and older adults. Annals of hematology 20040101
Activity of topoisomerase inhibitors daunorubicin, idarubicin, and aclarubicin in the Drosophila Somatic Mutation and Recombination Test. Environmental and molecular mutagenesis 20040101
Fluorescence-based assessment of LRP activity: a comparative study. Anticancer research 20040101
[Consolidation of therapy of acute myeloid leukemia with the AML-BFM 93 protocol in children in the Czech Republic]. Casopis lekaru ceskych 20040101
[Preliminary results of a multicenter randomized study on the treatment of acute promyelocytic leukemias]. Terapevticheskii arkhiv 20040101
[Damage of vascular endothelium in the treatment of acute leukemia: in vitro study]. Terapevticheskii arkhiv 20040101
Efficacy of granulocyte and granulocyte-macrophage colony-stimulating factors in the induction treatment of adult acute lymphoblastic leukemia: a multicenter randomized study. The hematology journal : the official journal of the European Haematology Association 20040101
All-transretinoic acid and chemotherapy in the treatment of acute promyelocytic leukemia. Indian journal of cancer 20040101
An effective in vitro antitumor response against human pancreatic carcinoma with paclitaxel and daunorubicin by induction of both necrosis and apoptosis. Anticancer research 20040101
Interactions of novel morpholine and hexamethylene derivatives of anthracycline antibiotics with DNA. Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101
CP-31398, a putative p53-stabilizing molecule tested in mammalian cells and in yeast for its effects on p53 transcriptional activity. Journal of negative results in biomedicine 20040101
The ability of new sugar-modified derivatives of antitumor anthracycline, daunorubicin, to stimulate NAD(P)H oxidation in different cellular oxidoreductase systems: NADH dehydrogenase, NADPH cytochrome P450 reductase, and xanthine oxidase. Oncology research 20040101
Cerebrospinal fluid excitatory amino acids and tau protein in children with acute lymphoblastic leukemia treated according to the BFM protocol. Acta haematologica 20040101
A bitter melon extract inhibits the P-glycoprotein activity in intestinal Caco-2 cells: monoglyceride as an active compound. BioFactors (Oxford, England) 20040101
[Immunologic monitoring in children with acute lymphoblastic leukemia during maintenance treatment with regard to co-existing infections]. Wiadomosci lekarskie (Warsaw, Poland : 1960) 20040101
[Vitrectomy with daunorubicin]. Klinika oczna 20040101
[Treatment results in children with standard-risk acute lymphoblastic leukemia. Report of the Polish Pediatric Leukemia/Lymphoma Study Group]. Przeglad lekarski 20040101
[Diagnostic significance of reticulocyte analysis by flow cytometry, in children with acute lymphoblastic leukaemia (ALL) on chemotherapy]. Medycyna wieku rozwojowego 20040101
Overexpression of P-glycoprotein in K562 cells does not confer resistance to the growth inhibitory effects of imatinib (STI571) in vitro. Blood 20031215
Resistance to different classes of drugs is associated with impaired apoptosis in childhood acute lymphoblastic leukemia. Blood 20031215
6-Thioguanine, cytarabine, and daunorubicin (TAD) and high-dose cytarabine and mitoxantrone (HAM) for induction, TAD for consolidation, and either prolonged maintenance by reduced monthly TAD or TAD-HAM-TAD and one course of intensive consolidation by sequential HAM in adult patients at all ages with de novo acute myeloid leukemia (AML): a randomized trial of the German AML Cooperative Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031215
Separate roles for the Golgi apparatus and lysosomes in the sequestration of drugs in the multidrug-resistant human leukemic cell line HL-60. The Journal of biological chemistry 20031212
Reversal of breast cancer resistance protein-mediated drug resistance by tryprostatin A. International journal of cancer 20031210
In vitro antileukemic effect of a new anthracycline analogue, MEN 11079. Leukemia research 20031201
Pumping of drugs by P-glycoprotein: a two-step process? The Journal of pharmacology and experimental therapeutics 20031201
Structure of DNA hexamer sequence d-CGATCG by two-dimensional nuclear magnetic resonance spectroscopy and restrained molecular dynamics. Journal of biomolecular structure & dynamics 20031201
Adult T-biphenotypic acute leukaemia: clinical and biological features and outcome. British journal of haematology 20031201
Secondary acute leukemia following mitoxantrone-based high-dose chemotherapy for primary breast cancer patients. Bone marrow transplantation 20031201
Carboxy derivatives of isoflavones as affinity carriers for cytotoxic drug targeting in adrenocortical H295R carcinoma cells. The Journal of endocrinology 20031201
Chloroma of the orbit in a non-leukemic adult: A case report. Orbit (Amsterdam, Netherlands) 20031201
MLL/AF-1p fusion in therapy-related early pre-B acute lymphoblastic leukemia with t(1;11)(p32;q23) translocation developing in the relapse phase of acute promyelocytic leukemia. International journal of hematology 20031201
[Recent advances in the treatment of acute myelogenous leukemia: a view of the new agents]. [Rinsho ketsueki] The Japanese journal of clinical hematology 20031201
Treatment of B-cell malignancies in children with a modified BFM-NHL 90 protocol in Argentina. Medical and pediatric oncology 20031101
Acute myeloid leukemia presenting as non-neutropenic colitis in an infant. Journal of pediatric gastroenterology and nutrition 20031101
Liposomal daunorubicin (DaunoXome) in multiple myeloma: a modified VAD regimen using short-term infusion. Anti-cancer drugs 20031101
Limited influence of P-glycoprotein on small-intestinal absorption of cilostazol, a high absorptive permeability drug. Journal of pharmaceutical sciences 20031101
Protein expression of the glucocorticoid receptor in childhood acute lymphoblastic leukemia. Haematologica 20031101
Cardiac troponin T as an indicator of reduced left ventricular contractility in experimental anthracycline-induced cardiomyopathy. Cancer chemotherapy and pharmacology 20031101
Low L-selectin (CD62L) expression in acute myeloid leukemia correlates with a bad cytogenetic risk. European journal of haematology 20031101
Persistent reversal of P-glycoprotein-mediated daunorubicin resistance by tetrandrine in multidrug-resistant human T lymphoblastoid leukemia MOLT-4 cells. The Journal of pharmacy and pharmacology 20031101
FLT3 internal tandem duplication in 234 children with acute myeloid leukemia: prognostic significance and relation to cellular drug resistance. Blood 20031001
Pilot study of gemtuzumab ozogamicin, liposomal daunorubicin, cytarabine and cyclosporine regimen in patients with refractory acute myelogenous leukemia. Leukemia research 20031001
Population pharmacokinetics of liposomal daunorubicin in children. British journal of clinical pharmacology 20031001
Tumor acidity, ion trapping and chemotherapeutics. I. Acid pH affects the distribution of chemotherapeutic agents in vitro. Biochemical pharmacology 20031001
Chemotherapy increases transgene expression in leukemic cells. The journal of gene medicine 20031001
[Hematologic tumors]. Gan to kagaku ryoho. Cancer & chemotherapy 20031001
Clinico-biologic features and treatment outcome of adult pro-B-ALL patients enrolled in the GIMEMA 0496 study: absence of the ALL1/AF4 and of the BCR/ABL fusion genes correlates with a significantly better clinical outcome. Blood 20030915
Anthracycline secondary alcohol metabolite formation in human or rabbit heart: biochemical aspects and pharmacologic implications. Biochemical pharmacology 20030915
Potentiation of tumour apoptosis by human growth hormone via glutathione production and decreased NF-kappaB activity. British journal of cancer 20030915
Lymphoblastic lymphoma of childhood and the LSA2-L2 protocol: the 30-year experience at Memorial-Sloan-Kettering Cancer Center. Cancer 20030915
Inhibition of membrane-associated calcium-independent phospholipase A2 as a potential culprit of anthracycline cardiotoxicity. Cancer research 20030915
BAALC expression predicts clinical outcome of de novo acute myeloid leukemia patients with normal cytogenetics: a Cancer and Leukemia Group B Study. Blood 20030901
Identification of binding mechanisms in single molecule-DNA complexes. Biophysical journal 20030901
Kinetic analysis of rhodamines efflux mediated by the multidrug resistance protein (MRP1). Biophysical journal 20030901
No benefit from adding GM-CSF to induction chemotherapy in transforming myelodysplastic syndromes: better outcome in patients with less proliferative disease. Leukemia 20030901
Viridans streptococcal sepsis: clinical features and complications in childhood acute myeloid leukemia. Journal of pediatric hematology/oncology 20030901
A randomized trial of induction therapy (daunorubicin, vincristine, prednisone versus daunorubicin, vincristine, prednisone, cytarabine and 6-thioguanine) in adult acute lymphoblastic leukemia with long-term follow-up: an Eastern Cooperative Oncology Group Study (E3486). Leukemia & lymphoma 20030901
Extramedullary acute myeloid leukemia (granulocytic sarcoma) with arm paresis, maculopapular exanthema and organ involvement. Leukemia & lymphoma 20030901
Pulmonary embolism and thrombotic thrombocytopenic purpura in acute promyelocytic leukemia treated with all-trans retinoic acid. Leukemia & lymphoma 20030901
Quantitative evaluation of isothiocyanates as substrates and inhibitors of P-glycoprotein. The Journal of pharmacy and pharmacology 20030901
Chromosomal rearrangement in Down syndrome with acute myeloid leukemia. Indian journal of pediatrics 20030901
Isolated IgA deficiency after chemotherapy for acute myelogenous leukemia in an infant. Pediatric hematology and oncology 20030901
Protein profiling in daunorubicin-induced cardiomyopathy. General physiology and biophysics 20030901
Analysis of single nucleotide polymorphism C3435T of the multidrug resistance gene MDR1 in acute lymphoblastic leukemia. International journal of oncology 20030801
A novel t(15;17) translocation in acute myeloid leukaemia not associated with PML/RARalpha rearrangement. Clinical and laboratory haematology 20030801
Acute arterial thrombosis in acute promyelocytic leukaemia. Clinical and laboratory haematology 20030801
New designs for phase 2 clinical trials. Blood 20030715
Prognosis of inv(16)/t(16;16) acute myeloid leukemia (AML): a survey of 110 cases from the French AML Intergroup. Blood 20030715
Crystal structure of chartreusin derivative A132. Carbohydrate research 20030704
Arsenic trioxide induces apoptosis in cells of MOLT-4 and its daunorubicin-resistant cell line via depletion of intracellular glutathione, disruption of mitochondrial membrane potential and activation of caspase-3. Cancer chemotherapy and pharmacology 20030701
Protection against Adriamycin cytotoxicity and inhibition of DNA topoisomerase II activity by 3,4-dihydroxybenzoic acid. International journal of oncology 20030701
Safety of high-dose liposomal daunorubicin (daunoxome) for refractory or relapsed acute myeloblastic leukaemia. British journal of haematology 20030701
Characterization of daunorubicin-induced apoptosis in retinal pigment epithelial cells: modulation by CD95L. Investigative ophthalmology & visual science 20030701
Oxidation of anthracycline anticancer agents by the peroxidase mimic microperoxidase 11 and hydrogen peroxide. Free radical biology & medicine 20030701
[Results and suggestion from comparing between world excellent protocols of childhood acute lymphoblastic leukemia]. Zhonghua er ke za zhi = Chinese journal of pediatrics 20030701
Daunorubicin-induced variations in gene transcription: commitment to proliferation arrest, senescence and apoptosis. The Biochemical journal 20030615
New findings in the study on the intercalation of bisdaunorubicin and its monomeric analogues with naked and nucleus DNA. Chemico-biological interactions 20030615
Stress-induced activation of GATA-4 in cardiac muscle cells. Free radical biology & medicine 20030615
Imatinib Mesylate (Gleevec) is a useful agent in the salvage treatment of adults with relapsed/refractory Philadelphia positive acute leukemias. Hematology (Amsterdam, Netherlands) 20030601
Dexamethasone-associated toxicity during induction chemotherapy for childhood acute lymphoblastic leukemia is augmented by concurrent use of daunomycin. Cancer 20030601
Cytotoxic drugs enhance the ex vivo sensitivity of malignant cells from a subset of acute myeloid leukaemia patients to apoptosis induction by tumour necrosis factor receptor-related apoptosis-inducing ligand. British journal of haematology 20030601
Cytosolic beta-glycosidases for activation of glycoside prodrugs of daunorubicin. Biochemical pharmacology 20030601
Anthracycline-dependent heat-induced transition from positive to negative supercoiled DNA. Electrophoresis 20030601
Long-term survival in acute lymphoblastic leukaemia in adults treated according to the LALA 87 protocol. Chemotherapy 20030601
[Successful treatment of acute promyelocytic leukemia in a pregnant patient with all-trans retinoic acid and chemotherapy resulting in a safe delivery]. [Rinsho ketsueki] The Japanese journal of clinical hematology 20030601
Modulation of P-glycoprotein-mediated multidrug resistance by flavonoid derivatives and analogues. Journal of medicinal chemistry 20030522
Characterisation of the brain multidrug resistance protein (BMDP/ABCG2/BCRP) expressed at the blood-brain barrier. Brain research 20030509
Immunophenotypic evidence of leukemia after induction therapy predicts relapse: results from a prospective Children's Cancer Group study of 252 patients with acute myeloid leukemia. Blood 20030501
Cholesterol-modulating agents kill acute myeloid leukemia cells and sensitize them to therapeutics by blocking adaptive cholesterol responses. Blood 20030501
Maternal and fetal outcomes in pregnancy complicated with acute leukemia: a single institutional experience with 10 pregnancies at 16 years. Leukemia research 20030501
Inactivation of deoxycytidine kinase and overexpression of P-glycoprotein in AraC and daunorubicin double resistant leukemic cell lines. Leukemia research 20030501
Immunophenotyping is an independent factor for risk stratification in AML. Cytometry. Part B, Clinical cytometry 20030501
Comparison of fludarabine-containing salvage chemotherapy regimens for relapsed/refractory acute myelogenous leukemia. Leukemia 20030501
Sustained complete hematologic remission after administration of the tyrosine kinase inhibitor imatinib mesylate in a patient with refractory, secondary AML. Blood 20030415
The endonuclease NL1Tc encoded by the LINE L1Tc from Trypanosoma cruzi protects parasites from daunorubicin DNA damage. Biochimica et biophysica acta 20030415
Human granulocyte colony-stimulating factor in children with high-risk acute lymphoblastic leukemia: a Children's Cancer Group Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030415
Structure of the first parallel DNA quadruplex-drug complex. Journal of the American Chemical Society 20030409
Isomer-dependent daunomycin release and in vitro antitumour effect of cis-aconityl-daunomycin. Biochemical and biophysical research communications 20030404
Thromboembolic events in children with acute lymphoblastic leukemia (BFM protocols): prednisone versus dexamethasone administration. Blood 20030401
A phase I/II study of the MDR modulator Valspodar (PSC 833) combined with daunorubicin and cytarabine in patients with relapsed and primary refractory acute myeloid leukemia. Leukemia research 20030401
Modeling the metabolism of idarubicin to idarubicinol in rat heart: effect of rutin and phenobarbital. Drug metabolism and disposition: the biological fate of chemicals 20030401
Multiple alterations of canalicular membrane transport activities in rats with CCl(4)-induced hepatic injury. Drug metabolism and disposition: the biological fate of chemicals 20030401
Fractionated cyclophosphamide, vincristine, liposomal daunorubicin, and dexamethasone plus rituximab and granulocyte-macrophage-colony stimulating factor (GM-CSF) alternating with methotrexate and cytarabine plus rituximab and GM-CSF in patients with Richter syndrome or fludarabine-refractory chronic lymphocytic leukemia. Cancer 20030401
Acute myeloid leukemia mimicking primary testicular neoplasm. Presentation of a case with review of literature. European journal of haematology 20030401
A novel nuclear DNA helicase with high specific activity from Pisum sativum catalytically translocates in the 3'-->5' direction. European journal of biochemistry 20030401
Autologous peripheral blood stem cell transplantation in first remission adult acute myeloid leukaemia--an intention to treat analysis and comparison of outcome using a predictive model based on the MRC AML10 cohort. Hematology (Amsterdam, Netherlands) 20030401
Association of genomic imbalances with drug resistance and thermoresistance in human gastric carcinoma cells. International journal of cancer 20030301
Successful chemotherapy for melanotic neuroectodermal tumor of infancy in a baby. Medical and pediatric oncology 20030301
High survival rate in childhood non-Hodgkin lymphoma without CNS involvement: results of BFM 95 study in Kuwait. Pediatric hematology and oncology 20030301
Benign intracranial hypertension in association with acute lymphoblastic leukemia. Pediatric hematology and oncology 20030301
A randomized trial of liposomal daunorubicin and cytarabine versus liposomal daunorubicin and topotecan with or without thalidomide as initial therapy for patients with poor prognosis acute myelogenous leukemia or myelodysplastic syndrome. Cancer 20030301
Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport. The Journal of pharmacology and experimental therapeutics 20030301
Telomerase inhibition enhances apoptosis in human acute leukemia cells: possibility of antitelomerase therapy. Leukemia 20030301
Efficacy of SCH66336, a farnesyl transferase inhibitor, in conjunction with imatinib against BCR-ABL-positive cells. Molecular cancer therapeutics 20030301
Reversal of P-glycoprotein-mediated multidrug resistance by protopanaxatriol ginsenosides from Korean red ginseng. Planta medica 20030301
Efficacy and toxicity of liposomal daunorubicin included in PVABEC regimen for aggressive NHL of the elderly. Leukemia & lymphoma 20030301
The dose related effect of steroids on blast reduction rate and event free survival in children with acute lymphoblastic leukemia. Leukemia & lymphoma 20030301
RU49953: a non-hormonal steroid derivative that potently inhibits P-glycoprotein and reverts cellular multidrug resistance. Cellular and molecular life sciences : CMLS 20030301
Protein kinase Czeta mediated Raf-1/extracellular-regulated kinase activation by daunorubicin. Blood 20030215
Inhibitors of vacuolar H+-ATPase impair the preferential accumulation of daunomycin in lysosomes and reverse the resistance to anthracyclines in drug-resistant renal epithelial cells. The Biochemical journal 20030215
Different effects of metabolic inhibitors and cyclosporin A on daunorubicin transport in leukemia cells from patients with AML. Leukemia research 20030201
Effect of flavonoids on MRP1-mediated transport in Panc-1 cells. Journal of pharmaceutical sciences 20030201
RNA interference is a functional pathway with therapeutic potential in human myeloid leukemia cell lines. Cancer gene therapy 20030201
High-dose consolidation chemotherapy with Idarubicin and alkylating agents following induction with gemcitabine-epirubicin-paclitaxel in metastatic breast cancer: a dose finding study. Bone marrow transplantation 20030201
Arsenic trioxide induces apoptosis equally in T lymphoblastoid leukemia MOLT-4 cells and P-gp-expressing daunorubicin-resistant MOLT-4 cells. Cancer chemotherapy and pharmacology 20030201
The cell cycle distribution of cultured human retinal pigmented epithelial cells under exposure of anti-proliferative drugs. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20030201
AML1 amplification in a child with acute lymphoblastic leukemia. Cancer genetics and cytogenetics 20030101
Morphological and biochemical changes in human fibroblast lines induced by anthracyclines during apoptosis. Cellular & molecular biology letters 20030101
[Arsenic trioxide inhibits P-glycoprotein expression in multidrug-resistant human leukemia K562/ADM cell line that overexpresses mdr-1 gene and enhances their chemotherapeutic sensitivity]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20030101
High-dose daunorubicin as liposomal compound (Daunoxome) in elderly patients with acute lymphoblastic leukemia. The hematology journal : the official journal of the European Haematology Association 20030101
[Selective isolation of actinomycetes of the genus Actinomadura from soil]. Mikrobiologiia 20030101
Effects of carvedilol on MDR1-mediated multidrug resistance: comparison with verapamil. Cancer science 20030101
[The assessment of plasma levels of insulin-like growth factor (IGF-I) and binding protein (IGFBP-3) during the maintenance therapy and after remissionof acute lymphoblastic leukemia (ALL)]. Endokrynologia, diabetologia i choroby przemiany materii wieku rozwojowego : organ Polskiego Towarzystwa Endokrynologow Dzieciecych 20030101
[The influence of age, gender and modifications of therapeutic protocols on physical development of children and adolescents after completion of therapy for acute lymphoblastic leukemia]. Endokrynologia, diabetologia i choroby przemiany materii wieku rozwojowego : organ Polskiego Towarzystwa Endokrynologow Dzieciecych 20030101
A case of leukemia of the appendix presenting as acute appendicitis. Acta haematologica 20030101
Disposition of liposomal daunorubicin during cotreatment with cytarabine in patients with leukaemia. Clinical pharmacokinetics 20030101
[Karyotype in acute myeloid leukemia: importance and type of aberrations in 30 patients at diagnosis]. Revista da Associacao Medica Brasileira (1992) 20030101
Liposomal anthracyclines in metastatic breast cancer: clinical update. The oncologist 20030101
Changes in GSH-antioxidant system induced by daunorubicin in human normal and diabetic fibroblasts. Acta biochimica Polonica 20030101
[Improved results in children with acute lymphoblastic leukemia treated with the ALL-BFM 90 protocol in the Czech Republic]. Casopis lekaru ceskych 20030101
Drug targeting by macromolecules without recognition unit? Journal of molecular recognition : JMR 20030101
Effect of quercetin on daunorubicin-induced heart mitochondria changes in rats. Physiological research 20030101
Granulocytic sarcoma of the pancreas. A report of one case and review of the literature. Acta haematologica 20030101
The interaction of daunorubicin and mitoxantrone with the red blood cells of acute myeloid leukemia patients. Cellular & molecular biology letters 20030101
Acute leukemia in pregnancy with ovarian metastasis: a case report and review of the literature. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20030101
[Effect of perfluoroorganic compounds on growth of streptomycetes and biosynthesis of antibiotic daunorubicin]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101
Anthracyclines. Cancer chemotherapy and biological response modifiers 20030101
Ganglioside GD3 sensitizes human hepatoma cells to cancer therapy. The Journal of biological chemistry 20021220
Synthesis and cytotoxic activity of a new potent daunomycinone derivative. Bioorganic & medicinal chemistry letters 20021216
All-trans retinoic acid in acute promyelocytic leukemia: long-term outcome and prognostic factor analysis from the North American Intergroup protocol. Blood 20021215
Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461). Blood 20021215
Induction of poly(ADP-ribose) polymerase-1 cleavage by antitumor triptycene bisquinones in wild-type and daunorubicin-resistant HL-60 cell lines. Cancer letters 20021215
Determination of free and liposome-associated daunorubicin and daunorubicinol in plasma by capillary electrophoresis. Journal of chromatography. A 20021206
Comparison of anthracycline-induced death of human leukemia cells: programmed cell death versus necrosis. Apoptosis : an international journal on programmed cell death 20021201
Outcome after induction chemotherapy for older patients with acute myeloid leukemia is not improved with mitoxantrone and etoposide compared to cytarabine and daunorubicin: a Southwest Oncology Group study. Blood 20021201
Design, synthesis and antitumor activities of novel 7-arylseleno-7-deoxydaunomycinone derivatives. Bioorganic & medicinal chemistry 20021201
P-glycoprotein-mediated transport of berberine across Caco-2 cell monolayers. Journal of pharmaceutical sciences 20021201
Overexpression of protein kinase Czeta confers protection against antileukemic drugs by inhibiting the redox-dependent sphingomyelinase activation. Molecular pharmacology 20021201
Voriconazole in the management of invasive aspergillosis in two patients with acute myeloid leukemia undergoing stem cell transplantation. Bone marrow transplantation 20021201
Favorable outcome with STI571 (imatinib mesylate) and allogeneic stem cell transplantation in a case of Ph+ chemorefractory acute lymphocytic leukaemia. Bone marrow transplantation 20021201
Intensified daunorubicin in induction therapy and autologous peripheral blood stem cell transplantation in postremission therapy (Double-7 protocol) for adult acute myeloid leukemia. International journal of hematology 20021201
Comparative study of chronic toxic effects of daunorubicin and doxorubicin in rabbits. Human & experimental toxicology 20021201
Promoter-specific inhibition of transcription by daunorubicin in Saccharomyces cerevisiae. The Biochemical journal 20021115
Analysis of rat bone marrow by flow cytometry following in vivo exposure to cyclohexanone oxime or daunomycin HCl. Toxicology and applied pharmacology 20021115
Improvement over time in outcome for children with acute lymphoblastic leukemia in second remission given hematopoietic stem cell transplantation from unrelated donors. Leukemia 20021101
Resistance of bcr-abl-positive acute lymphoblastic leukemia to daunorubicin is not mediated by mdr1 gene expression. American journal of hematology 20021101
The catalytic DNA topoisomerase II inhibitor ICRF-193 and all-trans retinoic acid cooperatively induce granulocytic differentiation of acute promyelocytic leukemia cells: candidate drugs for chemo-differentiation therapy against acute promyelocytic leukemia. Experimental hematology 20021101
Impact of granulocyte colony-stimulating factor use during induction for acute myelogenous leukemia in children: a report from the Children's Cancer Group. Journal of pediatric hematology/oncology 20021101
Methotrexate polyglutamation may lack prognostic significance in children with B-cell precursor acute lymphoblastic leukemia treated with intensive oral methotrexate. Journal of pediatric hematology/oncology 20021101
Blast crisis of chronic myeloid leukemia: diagnosis prompted by T(8;9). Journal of pediatric hematology/oncology 20021101
Pharmacokinetics of 2-chlorodeoxyadenosine in a child undergoing hemofiltration and hemodialysis for acute renal failure. Journal of pediatric hematology/oncology 20021101
Liposomal daunorubicin overcomes drug resistance in human breast, ovarian and lung carcinoma cells. Journal of liposome research 20021101
[Effect of tetrandrine and droloxifene on the reversion of drug resistance of K562/A02 cell line and induction of apoptosis]. Zhonghua zhong liu za zhi [Chinese journal of oncology] 20021101
Results of consecutive trials for children newly diagnosed with acute myeloid leukemia from the Australian and New Zealand Children's Cancer Study Group. Blood 20021015
Interim comparison of a continuous infusion versus a short daily infusion of cytarabine given in combination with cladribine for pediatric acute myeloid leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20021015
Inhibition of basal and transforming growth factor-beta-induced stimulation of COL1A1 transcription by the DNA intercalators, mitoxantrone and WP631, in cultured human dermal fibroblasts. The Journal of biological chemistry 20021011
Daunorubicin- and Ara-C-induced interphasic apoptosis of human type II leukemia cells is caspase-8-independent. Biochimica et biophysica acta 20021010
Overexpression and functional characterization of an ABC (ATP-binding cassette) transporter encoded by the genes drrA and drrB of Mycobacterium tuberculosis. The Biochemical journal 20021001
Ara-C- and daunorubicin-induced recruitment of Lyn in sphingomyelinase-enriched membrane rafts. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021001
Role of daunorubicin in inhibiting proliferative vitreoretinopathy after retinal detachment surgery. Clinical & experimental ophthalmology 20021001
Effect of organic isothiocyanates on the P-glycoprotein- and MRP1-mediated transport of daunomycin and vinblastine. Pharmaceutical research 20021001
Fulminant tumour lysis syndrome in acute myelogenous leukaemia with inv(16)(p13;q22). European journal of haematology 20021001
Long-term outcomes of acute myeloid leukemia in adults in Pakistan. JPMA. The Journal of the Pakistan Medical Association 20021001
Induction of metallothionein by zinc protects from daunorubicin toxicity in rats. Toxicology 20020930
Inhibitory effect of chamomile essential oil on the sister chromatid exchanges induced by daunorubicin and methyl methanesulfonate in mouse bone marrow. Toxicology letters 20020905
Role of exogenous melatonin in reducing the nephrotoxic effect of daunorubicin and doxorubicin in the rat. Journal of pineal research 20020901
Management of acute promyelocytic leukemia. Current oncology reports 20020901
Liposomal daunorubicin (DaunoXome) for treatment of relapsed meningeal acute myeloid leukemia. Leukemia 20020901
A successful second unrelated BMT (UBMT) from a different unrelated donor to treat ALL that relapsed after the initial UBMT. American journal of hematology 20020901
Central nervous system relapse in acute promyelocytic leukemia. American journal of hematology 20020901
Postremission therapy with low-dose interleukin 2 with or without intermediate pulse dose interleukin 2 therapy is well tolerated in elderly patients with acute myeloid leukemia: Cancer and Leukemia Group B study 9420. Clinical cancer research : an official journal of the American Association for Cancer Research 20020901
Acute myelogenous leukemia following treatment with cyclosporin A in a nephrotic patient. Internal medicine (Tokyo, Japan) 20020901
[In vitro study of the apoptosis effect of DNR on HL-60 cells and its relationship with ROS, CER and NF-kappaB]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20020901
Phase 3 study of the multidrug resistance modulator PSC-833 in previously untreated patients 60 years of age and older with acute myeloid leukemia: Cancer and Leukemia Group B Study 9720. Blood 20020815
Subcellular daunorubicin distribution and its relation to multidrug resistance phenotype in drug-resistant cell line SMMC-7721/R. World journal of gastroenterology 20020815
Reversal of multidrug resistance-associated protein-mediated daunorubicin resistance by camptothecin. Journal of pharmaceutical sciences 20020801
Influence of ceramide metabolism on P-glycoprotein function in immature acute myeloid leukemia KG1a cells. Molecular pharmacology 20020801
SAB--a promising new treatment to improve remission rates in AML in the elderly? British journal of haematology 20020801
Anti-angiogenic activity of the purine analog 6-thioguanine. Leukemia 20020801
In vitro effects of combination chemotherapy on osteoblasts: implications for osteopenia in childhood malignancy. Bone 20020801
Acute lymphoblastic leukemia in the context of a disorder resembling X-linked lymphoproliferative (XLP) syndrome. Haematologica 20020801
Tuberculosis and immune thrombocytopenia. Haematologica 20020801
Role of apoptosis in the cytotoxic effect mediated by daunorubicin in cultured human retinal pigment epithelial cells. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20020801
Liposomal daunorubicin (DaunoXome) for treatment of poor-risk acute leukemia. Annals of hematology 20020801
[Progress in the field of hematology in the last 100 years: Medical history of acute leukemia]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20020710
CD56 expression predicts occurrence of CNS disease in acute lymphoblastic leukemia. Leukemia research 20020701
Modulation of the atypical multidrug-resistant phenotype by a hammerhead ribozyme directed against the ABC transporter BCRP/MXR/ABCG2. Cancer gene therapy 20020701
A phase I dose-escalating study of DaunoXome, liposomal daunorubicin, in metastatic breast cancer. British journal of cancer 20020701
Suicide gene therapy using E. coli beta-galactosidase. Cancer chemotherapy and pharmacology 20020701
Symptomatic hypoglycemia in children receiving oral purine analogues for treatment of childhood acute lymphoblastic leukemia. Medical and pediatric oncology 20020701
Variant translocations of 11q23 in infant acute lymphoblastic leukemia (ALL): do outcomes differ from t(4;11)? Medical and pediatric oncology 20020701
Increased factor VIII activity and dural sinus thrombosis. Medical and pediatric oncology 20020701
Multiple mechanisms confer different drug-resistant phenotypes in pancreatic carcinoma cells. Journal of cancer research and clinical oncology 20020701
Among substituted 9,10-dihydro-9,10-[1,2]benzenoanthracene-1,4,5,8-tetraones, the lead antitumor triptycene bisquinone TT24 blocks nucleoside transport, induces apoptotic DNA fragmentation and decreases the viability of L1210 leukemic cells in the nanomolar range of daunorubicin in vitro. Anti-cancer drugs 20020701
Spectroelectrochemical study of the interaction between antitumor drug daunomycin and DNA in the presence of antioxidants. Journal of pharmaceutical and biomedical analysis 20020620
Potent inhibition of DNA unwinding and ATPase activities of pea DNA helicase 45 by DNA-binding agents. Biochemical and biophysical research communications 20020607
Resistance to daunorubicin-induced apoptosis is not completely reversed in CML blast cells by STI571. Leukemia 20020601
Competitive interaction of the antitumor drug daunorubicin and the fluorescence probe ethidium bromide with DNA as studied by resolving trilinear fluorescence data: the use of PARAFAC and its modification. Analytical and bioanalytical chemistry 20020601
Homocysteine and folate status in methotrexate-treated patients with rheumatoid arthritis. Rheumatology (Oxford, England) 20020601
Influence of chemosensitizers on resistance mechanisms in daunorubicin-resistant Ehrlich ascites tumour cells. Cancer chemotherapy and pharmacology 20020601
Downregulation of taurine uptake in multidrug resistant Ehrlich ascites tumor cells. Amino acids 20020601
Monitoring daunorubicin-induced alterations in protein expression in pancreas carcinoma cells by two-dimensional gel electrophoresis. Proteomics 20020601
Tetrasomy 13 as the sole cytogenetic abnormality in acute myeloid leukemia M1 without maturation. Cancer genetics and cytogenetics 20020601
A case of acantholytic dermatosis and leukemia cutis: cause or effect? The American Journal of dermatopathology 20020601
Transfusion medicine illustrated. White out: extreme leukocytosis treated with WBC reduction. Transfusion 20020601
Methotrexate induced seizures associated with acute reversible magnetic resonance imaging (MRI) changes in a patient with acute lymphoblastic leukemia. Leukemia & lymphoma 20020601
Long-term follow-up of patients >or=60 yr old with acute myeloid leukaemia treated with intensive chemotherapy. European journal of haematology 20020601
Drug sensitivity assay for leukaemic cells by flow cytometry. The Indian journal of medical research 20020601
Low level of mitochondrial deoxyguanosine kinase is the dominant factor in acquired resistance to 9-beta-D-arabinofuranosylguanine cytotoxicity. Biochemical and biophysical research communications 20020524
Intensified and shortened cyclical chemotherapy for adult acute lymphoblastic leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020515
Formation and longevity of idarubicin-induced DNA topoisomerase II cleavable complexes in K562 human leukaemia cells. Biochemical pharmacology 20020515
Liposomal daunorubicin (DaunoXome) plus dexamethasone for patients with multiple myeloma. A phase II International Oncology Study Group study. Cancer 20020515
Gynecomastia with marked cellular atypia associated with chemotherapy. Archives of pathology & laboratory medicine 20020501
Maleimide is a potent inhibitor of topoisomerase II in vitro and in vivo: a new mode of catalytic inhibition. Molecular pharmacology 20020501
Liposomal encapsulation diminishes daunorubicin-induced generation of reactive oxygen species, depletion of ATP and necrotic cell death in human leukaemic cells. British journal of haematology 20020501
Induction of multidrug resistance in MOLT-4 cells by anticancer agents is closely related to increased expression of functional P-glycoprotein and MDR1 mRNA. Cancer chemotherapy and pharmacology 20020501
Pharmacokinetics and tissue distribution of idarubicin-loaded solid lipid nanoparticles after duodenal administration to rats. Journal of pharmaceutical sciences 20020501
Dexrazoxane has no impact on sensitivity of childhood leukemic blasts to daunorubicin. Leukemia 20020501
NMR determination of the hetero-association of phenanthridines with daunomycin and their competitive binding to a DNA oligomer. European biophysics journal : EBJ 20020501
Homocamptothecin-daunorubicin association overcomes multidrug-resistance in breast cancer MCF7 cells. Breast cancer research and treatment 20020501
Comparison of idarubicin and daunorubicin regarding intracellular uptake, induction of apoptosis, and resistance. Cancer letters 20020425
Preferential efflux by P-glycoprotein, but not MRP1, of compounds containing a free electron donor amine. Biochemical pharmacology 20020415
Interaction of daunomycin antibiotic with histone H(1): ultraviolet spectroscopy and equilibrium dialysis studies. International journal of biological macromolecules 20020408
Clinical severe hepatic venoocclusive disease during induction treatment of acute monoblastic leukemia managed with defibrotide. American journal of hematology 20020401
Effects of dietary lipids on daunomycin-induced nephropathy in mice: comparison between cod liver oil and soybean oil. Lipids 20020401
D4-GDI is cleaved by caspase-3 during daunorubicin-induced apoptosis in HL-60 cells. Experimental & molecular medicine 20020331
Differential destabilization of membranes by tryptophan and phenylalanine during freezing: the roles of lipid composition and membrane fusion. Biochimica et biophysica acta 20020319
Enantioselective synthesis of (+)-4-demethoxy-1,4-dimethyldaunomycinone. Bioorganic & medicinal chemistry 20020301
Multiple interference of anthracyclines with mitochondrial creatine kinases: preferential damage of the cardiac isoenzyme and its implications for drug cardiotoxicity. Molecular pharmacology 20020301
Signals of oxidant-induced cardiomyocyte hypertrophy: key activation of p70 S6 kinase-1 and phosphoinositide 3-kinase. The Journal of pharmacology and experimental therapeutics 20020301
Chemotherapy and pregnancy. Clinical obstetrics and gynecology 20020301
Cuban experience in the treatment of acute promyelocytic leukemia with ALL transretinoic acid followed by intensive chemotherapy. Haematologica 20020301
Studies on quinazolinones as dual inhibitors of Pgp and MRP1 in multidrug resistance. Bioorganic & medicinal chemistry letters 20020225
Evaluation of the clinical relevance of the expression and function of P-glycoprotein, multidrug resistance protein and lung resistance protein in patients with primary acute myelogenous leukemia. Leukemia research 20020201
Acute T-lymphoblastic leukemia relapsed with the character of myeloid/natural killer cell precursor phenotype: a case report. Leukemia research 20020201
Phase IV study of liposomal daunorubicin (DaunoXome) in AIDS-related Kaposi sarcoma. American journal of clinical oncology 20020201
Electrochemical evaluation of the interaction between endocrine disrupter chemicals and estrogen receptor using 17,beta-estradiol labeled with daunomycin. Analytical chemistry 20020201
Hematopoietic cell transplantation beyond first remission. Leukemia 20020201
Prognostic significance of the null genotype of glutathione S-transferase-T1 in patients with acute myeloid leukemia: increased early death after chemotherapy. Leukemia 20020201
Diversity of the apoptotic response to chemotherapy in childhood leukemia. Leukemia 20020201
C-Jun modulates apoptosis but not terminal cell differentiation in murine erythroleukemia cells. Leukemia 20020201
Safety and early efficacy assessment of liposomal daunorubicin (DaunoXome) in adults with refractory or relapsed acute myeloblastic leukaemia: a phase I-II study. British journal of haematology 20020201
Role of exogenous melatonin in reducing the cardiotoxic effect of daunorubicin and doxorubicin in the rat. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20020201
Comparison of Pgp- and MRP-mediated multidrug resistance in leukemia cell lines. International journal of hematology 20020201
In vivo analysis of human multidrug resistance protein 1 (MRP1) activity using transient expression of fluorescently tagged MRP1. Cancer research 20020115
The proline-rich domain of p53 is required for cooperation with anti-neoplastic agents to promote apoptosis of tumor cells. Oncogene 20020103
PK11195, a peripheral benzodiazepine receptor ligand, chemosensitizes acute myeloid leukemia cells to relevant therapeutic agents by more than one mechanism. Leukemia research 20020101
Prognosis of elderly patients with acute myelogenous leukemia: analysis of 126 AML cases. International journal of hematology 20020101
Philadelphia chromosome-positive acute myeloid leukemia with tetraploidy. International journal of hematology 20020101
In vitro studies of haematopoietic colony-forming capacity of human fetal liver cells at exposure to cytotoxic and immunomodulatory drugs. Fetal diagnosis and therapy 20020101
Assessment of drug activity and proliferation ex vivo for prediction of outcome in aggressive non-Hodgkin's lymphomas. Acta oncologica (Stockholm, Sweden) 20020101
Imaging of P glycoprotein function in vivo with PET. Novartis Foundation symposium 20020101
Correlation of histopathological and biochemical appraisal of anthracyclin-induced myocardium damage. Folia histochemica et cytobiologica 20020101
Activity of drugs from traditional Chinese medicine toward sensitive and MDR1- or MRP1-overexpressing multidrug-resistant human CCRF-CEM leukemia cells. Blood cells, molecules & diseases 20020101
Involvement of glutathione and glutathione-related enzymes in the protection of normal and trisomic human fibroblasts against daunorubicin. Cell biology international 20020101
Overexpression of protein disulfide isomerase-like protein in a mouse leukemia L1210 cell line selected for resistance to 4-methyl-5-amino-1-formylisoquinoline thiosemicarbazone, a ribonucleotide reductase inhibitor. Advances in enzyme regulation 20020101
The influence of intracellular idarubicin and daunorubicin levels on drug cytotoxicity in childhood acute leukemia. Acta biochimica Polonica 20020101
Troponins in experimental studies. Acta medica (Hradec Kralove) 20020101
CD7+ and CD56+ myeloid/natural killer cell precursor acute leukemia treated with idarubicin and cytosine arabinoside. Acta haematologica 20020101
[Liposomal daunorubicine combined with cytarabine in the treatment of relapsed/refractory acute myeloid leukemia in children]. Klinische Padiatrie 20020101
[Effect of intercalators on the properties of liquid-crystalline dispersions of nucleic acid-chitosan complex]. Molekuliarnaia biologiia 20020101
Folate receptor targeted delivery of liposomal daunorubicin into tumor cells. Anticancer research 20020101
[Liposomal daunorubicin and interferon-alfa in combination with all-retinoic acid--a new regime for the treatment of acute promyelocytic leukemia]. Terapevticheskii arkhiv 20020101
Decreased sensitivity of neonatal rabbit sarcoplasmic reticulum to anthracycline cardiotoxicity. Cardiovascular toxicology 20020101
Effect of aging on cardiac contractility in a rat model of chronic daunorubicin cardiotoxicity. Cardiovascular toxicology 20020101
PK11195, an isoquinoline carboxamide ligand of the mitochondrial benzodiazepine receptor, increased drug uptake and facilitated drug-induced apoptosis in human multidrug-resistant leukemia cells in vitro. Neoplasma 20020101
[NMR study of complex formation of aromatic ligands with heptadeoxynucleotide 5'-d(GCGAAGC) forming stable hairpin structure in aqueous solution]. Molekuliarnaia biologiia 20020101
P-glycoprotein expression by cancer cells affects cell cytotoxicity and cell-cycle perturbations induced by six chemotherapeutic drugs. Journal of experimental therapeutics & oncology 20020101
[Results of the treatment of childhood acute lymphoblastic leukemia according to the Berlin-Moscow-91 protocol in 1991-2000]. Voprosy onkologii 20020101
Bilateral retinal hemorrhages in an 18-year-old woman. Survey of ophthalmology 20020101
Effect of sodium 2,3-dimercaptopropane-1-sulphonate (DMPS) on chronic daunorubicin toxicity in rabbits: comparison with dexrazoxane. Acta medica (Hradec Kralove) 20020101
Effect of melatonin on cytotoxic effects of daunorubicin on myocardium and on transplantable Morris hepatoma in rats. Polish journal of pathology : official journal of the Polish Society of Pathologists 20020101
Apoptosis of leukemia cells induced by CD34+ cells transferred exogenous Fas ligand. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20020101
Maximum-entropy determination of self-association distribution functions; daunorubicin and ATP. Biophysical chemistry 20011225
Peroxidase- and nitrite-dependent metabolism of the anthracycline anticancer agents daunorubicin and doxorubicin. Biochemistry 20011218
Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2. The EMBO journal 20011203
A synthetic triptycene bisquinone, which blocks nucleoside transport and induces DNA fragmentation, retains its cytotoxic efficacy in daunorubicin-resistant HL-60 cell lines. International journal of oncology 20011201
Benefit of cyclosporine modulation of drug resistance in patients with poor-risk acute myeloid leukemia: a Southwest Oncology Group study. Blood 20011201
Low relapse rate in children with acute lymphoblastic leukemia after risk-directed therapy. Journal of pediatric hematology/oncology 20011201
Renal cell carcinoma as a secondary malignancy after treatment of acute promyelocytic leukemia. Journal of pediatric hematology/oncology 20011201
Herpesvirus-6 encephalitis complicated by Wernicke-Korsakoff syndrome in a pediatric recipient of unrelated cord blood transplantation. Journal of pediatric hematology/oncology 20011201
An adjustment for a post-randomization variable in the comparison of two treatments for survival. Statistics in medicine 20011130
Anthracyclines: recent developments in their separation and quantitation. Journal of chromatography. B, Biomedical sciences and applications 20011125
Cell membrane transport of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the liver and systemic bioavailability. Biochemical and biophysical research communications 20011123
Expression of P-glycoprotein and multidrug resistance associated protein in Ehrlich ascites tumor cells after fractionated irradiation. International journal of radiation oncology, biology, physics 20011115
Crocin suppresses tumor necrosis factor-alpha-induced cell death of neuronally differentiated PC-12 cells. Life sciences 20011102
Breast cancer resistance protein expression and resistance to daunorubicin in blast cells from patients with acute myeloid leukaemia. British journal of haematology 20011101
Synthetic 1,4-anthracenediones, which block nucleoside transport and induce DNA fragmentation, retain their cytotoxic efficacy in daunorubicin-resistant HL-60 cell lines. Anti-cancer drugs 20011101
Comparison of long-term outcome of children and adolescents with disseminated non-lymphoblastic non-Hodgkin lymphoma treated with COMP or daunomycin-COMP: A report from the Children's Cancer Group. Medical and pediatric oncology 20011101
Influence of P-glycoprotein modulators on cardiac uptake, metabolism, and effects of idarubicin. Pharmaceutical research 20011101
Evidence for simultaneous binding of dissimilar substrates by the Escherichia coli multidrug transporter MdfA. Biochemistry 20011023
The farnesyl protein transferase inhibitor SCH66336 is a potent inhibitor of MDR1 product P-glycoprotein. Cancer research 20011015
Elevation of glucosylceramide in multidrug-resistant cancer cells and accumulation in cytoplasmic droplets. International journal of cancer 20011015
Kit signaling and negative regulation of daunorubicin-induced apoptosis: role of phospholipase Cgamma. Oncogene 20011011
Spectroscopic studies on iron complexes of different anthracyclines in aprotic solvent systems. Inorganic chemistry 20011008
The role of ceramide in receptor- and stress-induced apoptosis studied in acidic ceramidase-deficient Farber disease cells. Oncogene 20011004
Intensive timed sequential remission induction chemotherapy with high-dose cytarabine for childhood acute myeloid leukemia. Medical and pediatric oncology 20011001
In vitro effects of dexrazoxane (Zinecard) and classical acute leukemia therapy: time to consider expanded clinical trials? Leukemia 20011001
A pharmacokinetic study of idarubicin in Japanese patients with malignant lymphoma: relationship with leukocytopenia and neutropenia. International journal of hematology 20011001
Acute arterial occlusion as the presenting feature in acute promyelocytic leukaemia. British journal of haematology 20011001
FAB M4 and high CD14 surface expression is associated with high cellular resistance to Ara-C and daunorubicin: implications for clinical outcome in acute myeloid leukaemia. European journal of haematology 20011001
Benign thymic hyperplasia after chemotherapy for acute myeloid leukemia. European journal of haematology 20011001
Development of obesity and neurochemical backing in aurothioglucose-treated mice. Autonomic neuroscience : basic & clinical 20010917
Attempts to improve treatment outcomes in acute myeloid leukemia (AML) in older patients: the results of the United Kingdom Medical Research Council AML11 trial. Blood 20010901
The predictive value of hierarchical cytogenetic classification in older adults with acute myeloid leukemia (AML): analysis of 1065 patients entered into the United Kingdom Medical Research Council AML11 trial. Blood 20010901
Efficiency of homocysteine plus copper in inducing apoptosis is inversely proportional to gamma-glutamyl transpeptidase activity. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010901
Therapy-related CD7+ acute myeloid leukemia with trisomy 8 following acute monocytic leukemia. Anti-cancer drugs 20010901
Signaling pathways activated by daunorubicin. Blood 20010815
A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia. Blood 20010815
Evaluation of the interaction of loratadine and desloratadine with P-glycoprotein. Drug metabolism and disposition: the biological fate of chemicals 20010801
Erythroleukaemia in the north of England: a population based study. Journal of clinical pathology 20010801
Production of aromatic minimal polyketides by the daunorubicin polyketide synthase genes reveals the incompatibility of the heterologous DpsY and JadI cyclases. Journal of natural products 20010801
Successful treatment of hepatosplenic candidiasis in an elderly patient with acute myeloid leukemia using liposomal daunorubicin and fluconazole. Haematologica 20010801
Determination of anthracycline antibiotics doxorubicin and daunorubicin by capillary electrophoresis with UV absorption detection. Electrophoresis 20010801
Remission induction therapy: the more intensive the better? Cancer chemotherapy and pharmacology 20010801
Daunorubicin inhibits gene expression of cyclooxygenase-2 in vascular smooth muscle cells. Thrombosis research 20010801
Quantification of daunorubicin and daunorubicinol in plasma by capillary electrophoresis. Journal of chromatography. B, Biomedical sciences and applications 20010715
Role of ceramide in mediating the inhibition of telomerase activity in A549 human lung adenocarcinoma cells. The Journal of biological chemistry 20010706
Early onset Pneumocystis carinii pneumonia after allogeneic peripheral blood stem cell transplantation. American journal of hematology 20010701
Involvement of FAN in TNF-induced apoptosis. The Journal of clinical investigation 20010701
High-dose liposomal daunorubicin and high-dose cytarabine combination in patients with refractory or relapsed acute myelogenous leukemia. Cancer 20010701
Outcome of acute lymphoblastic leukemia in children with AL90 regimen: impact of response to treatment and sex difference on prognostic factors. Medical and pediatric oncology 20010701
Treatment of acute promyelocytic leukaemia using a combination of all-trans retinoic acid and chemotherapy. Annals of the Academy of Medicine, Singapore 20010701
Migration of retinal pigment epithelial cells in vitro modulated by monocyte chemotactic protein-1: enhancement and inhibition. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20010701
Repetitious appearance and disappearance of different kinds of clonal cytogenetic abnormalities after allogeneic bone marrow transplantation. International journal of hematology 20010701
Induction of apoptosis in MDR1 expressing cells by daunorubicin with combinations of suboptimal concentrations of P-glycoprotein modulators. Cancer letters 20010626
Effect of P-glycoprotein modulators on the human extraneuronal monoamine transporter. European journal of pharmacology 20010622
Separation and determination of liposomal and non-liposomal daunorubicin from the plasma of patients treated with Daunoxome. Journal of chromatography. B, Biomedical sciences and applications 20010615
Modulation by LY335979 of P-glycoprotein function in multidrug-resistant cell lines and human natural killer cells. Biochemical pharmacology 20010601
Collateral sensitivity to gemcitabine (2',2'-difluorodeoxycytidine) and cytosine arabinoside of daunorubicin- and VM-26-resistant variants of human small cell lung cancer cell lines. Biochemical pharmacology 20010601
Comparison of 'sequential' versus 'standard' chemotherapy as re-induction treatment, with or without cyclosporine, in refractory/relapsed acute myeloid leukaemia (AML): results of the UK Medical Research Council AML-R trial. British journal of haematology 20010601
Patterns of failure with increasing intensification of induction chemotherapy for acute myeloid leukaemia. British journal of haematology 20010601
Kinetics of glutathione and daunorubicin efflux from multidrug resistance protein overexpressing small-cell lung cancer cells. European journal of pharmacology 20010601
Melanocyte-Directed enzyme prodrug therapy (MDEPT): development of second generation prodrugs for targeted treatment of malignant melanoma. Bioorganic & medicinal chemistry 20010601
Magnetic resonance imaging detection of avascular necrosis of the bone in children receiving intensive prednisone therapy for acute lymphoblastic leukemia or non-Hodgkin lymphoma. Leukemia 20010601
Daunorubicin continuous infusion induces more toxicity than bolus infusion in acute lymphoblastic leukemia induction regimen: a randomized study. Leukemia 20010601
The prognostic value of cytogenetics is reinforced by the kind of induction/consolidation therapy in influencing the outcome of acute myeloid leukemia--analysis of 848 patients. Leukemia 20010601
Amplification of ERBB2, RARA, and TOP2A genes in a myelodysplastic syndrome transforming to acute myeloid leukemia. Cancer genetics and cytogenetics 20010601
True histiocytic lymphoma following B-acute lymphoblastic leukaemia: case report with evidence for a common clonal origin in both neoplasms. British journal of haematology 20010601
[Primary pulmonary manifestation of extramedullary acute myelocytic leukemia]. Pneumologie (Stuttgart, Germany) 20010601
Recent developments in the field of antitumour anthracyclines. European journal of medicinal chemistry 20010601
Alterative and plastic insufficiency of cardiomyocytes: isoproterenol-induced damage to myocardium during anthracycline cardiomyopathy. Bulletin of experimental biology and medicine 20010601
Liposomal daunorubicin (DaunoXome) in combination with cyclophosphamide, vincristine and prednisolone (COP-X) as salvage therapy in poor-prognosis non-Hodgkins lymphoma. Leukemia & lymphoma 20010601
Increase of ceramides and its inhibition by catalase during chemically induced apoptosis of HL-60 cells determined by electrospray ionization tandem mass spectrometry. Biochimica et biophysica acta 20010531
Improved treatment results in high-risk pediatric acute myeloid leukemia patients after intensification with high-dose cytarabine and mitoxantrone: results of Study Acute Myeloid Leukemia-Berlin-Frankfurt-Münster 93. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010515
Melanin potentiates daunorubicin-induced inhibition of collagen biosynthesis in human skin fibroblasts. European journal of pharmacology 20010511
Intracellular P-gp contributes to functional drug efflux and resistance in acute myeloid leukaemia. Leukemia research 20010501
Treatment of childhood acute lymphoblastic leukemia. Long-term results of the AIEOP-ALL 87 study. Haematologica 20010501
[Subcellular distribution of daunorubicin in the P-glycoprotein-mediated multidrug-resistant cell line K562/ADR]. Zhonghua zhong liu za zhi [Chinese journal of oncology] 20010501
Determination of binding thermodynamics. Current protocols in nucleic acid chemistry 20010501
Daunorubicin attenuates tumor necrosis factor-alpha-induced biosynthesis of plasminogen activator inhibitor-1 in human umbilical vein endothelial cells. Biochimica et biophysica acta 20010423
Value of high-dose cytarabine during interval therapy of a Berlin-Frankfurt-Munster-based protocol in increased-risk children with acute lymphoblastic leukemia and lymphoblastic lymphoma: results of the European Organization for Research and Treatment of Cancer 58881 randomized phase III trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010401
Dexrazoxane significantly impairs the induction of doxorubicin resistance in the human leukaemia line, K562. British journal of cancer 20010401
Acute myeloid leukemia cells are protected from spontaneous and drug-induced apoptosis by direct contact with a human bone marrow stromal cell line (HS-5). Experimental hematology 20010401
Determinants of outcome after intensified therapy of childhood lymphoblastic leukaemia: results from Medical Research Council United Kingdom acute lymphoblastic leukaemia XI protocol. British journal of haematology 20010401
Long-term outcome of treatment with protocols AL841, AL851, and ALHR88 in children with acute lymphoblastic leukemia: results obtained by the Kyushu-Yamaguchi Children's Cancer Study Group. International journal of hematology 20010401
PNU-159548, a novel cytotoxic antitumor agent with a low cardiotoxic potential. Cancer chemotherapy and pharmacology 20010401
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Results of therapy with interferon alpha and cyclic combination chemotherapy in patients with philadelphia chromosome positive chronic myelogenous leukemia in early chronic phase. Leukemia & lymphoma 20010401
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