(3,4-Dihydro-2H-pyrano[2,3-b]quinolin-7-yl)-(cis-4-methoxycyclohexyl)-methanone
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Antagonism of metabotropic glutamate 1 receptors attenuates behavioral effects of cocaine and methamphetamine in squirrel monkeys. | The Journal of pharmacology and experimental therapeutics 20121001 |
Subregion-specific role of glutamate receptors in the nucleus accumbens on drug context-induced reinstatement of cocaine-seeking behavior in rats. | Addiction biology 20120301 |
Group I metabotropic glutamate receptor antagonists alter select behaviors in a mouse model for fragile X syndrome. | Psychopharmacology 20120101 |
Estrogen receptors and type 1 metabotropic glutamate receptors are interdependent in protecting cortical neurons against β-amyloid toxicity. | Molecular pharmacology 20120101 |
Metabotropic glutamate antagonists alone and in combination with morphine: comparison across two models of acute pain and a model of persistent, inflammatory pain. | Behavioural pharmacology 20111201 |
Protective role for type-1 metabotropic glutamate receptors against spike and wave discharges in the WAG/Rij rat model of absence epilepsy. | Neuropharmacology 20110601 |
Characterization of the selective mGluR1 antagonist, JNJ16259685, in rodent models of movement and coordination. | Pharmacology, biochemistry, and behavior 20110401 |
Synthesis and evaluation of 6-[1-(2-[(18)F]fluoro-3-pyridyl)-5-methyl-1H-1,2,3-triazol-4-yl]quinoline for positron emission tomography imaging of the metabotropic glutamate receptor type 1 in brain. | Bioorganic & medicinal chemistry 20110101 |
Evaluation of cannabinoid receptor 2 and metabotropic glutamate receptor 1 functional responses using a cell impedance-based technology. | Journal of biomolecular screening 20101201 |
Pharmacological effects of metabotropic glutamate receptor ligands on prepulse inhibition in DBA/2J mice. | European journal of pharmacology 20100810 |
Effects of mGluR1 antagonism in the dorsal hippocampus on drug context-induced reinstatement of cocaine-seeking behavior in rats. | Psychopharmacology 20100101 |
Role of the metabotropic glutamate receptor subtype 1 in the harmaline-induced tremor in rats. | Journal of neural transmission (Vienna, Austria : 1996) 20090901 |
Inhibition of mGluR1 and IP3Rs impairs long-term memory formation in young chicks. | Neurobiology of learning and memory 20080701 |
JNJ16259685, a selective mGlu1 antagonist, suppresses isolation-induced aggression in male mice. | European journal of pharmacology 20080531 |
Involvement of subtype 1 metabotropic glutamate receptors in apoptosis and caspase-7 over-expression in spinal cord of neuropathic rats. | Pharmacological research 20080301 |
Regulation of motivation to self-administer ethanol by mGluR5 in alcohol-preferring (P) rats. | Alcoholism, clinical and experimental research 20080201 |
Effects of mGlu1-receptor blockade on ethanol self-administration in inbred alcohol-preferring rats. | Alcohol (Fayetteville, N.Y.) 20080201 |
Metabotropic glutamate receptor 1 blockade impairs acquisition and retention in a spatial Water maze task. | Behavioural brain research 20051014 |
Synthesis, structure-activity relationship, and receptor pharmacology of a new series of quinoline derivatives acting as selective, noncompetitive mGlu1 antagonists. | Journal of medicinal chemistry 20050324 |
JNJ16259685, a highly potent, selective and systemically active mGlu1 receptor antagonist. | Neuropharmacology 20041201 |