2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid
Title | Journal |
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Indoleamine 2,3-dioxygenase mediates anhedonia and anxiety-like behaviors caused by peripheral lipopolysaccharide immune challenge. | Hormones and behavior 20120801 |
Addition of an indoleamine 2,3,-dioxygenase inhibitor to B cell-depletion therapy blocks autoreactive B cell activation and recurrence of arthritis in K/BxN mice. | Arthritis and rheumatism 20120701 |
Induction of prolonged asthma tolerance by IL-10-differentiated dendritic cells: differential impact on airway hyperresponsiveness and the Th2 immunoinflammatory response. | Journal of immunology (Baltimore, Md. : 1950) 20120701 |
Effects of indoleamine 2,3-dioxygenases in carbon tetrachloride-induced hepatitis model of rats. | Cell biochemistry and function 20120601 |
Suppression of azoxymethane-induced colonic preneoplastic lesions in rats by 1-methyltryptophan, an inhibitor of indoleamine 2,3-dioxygenase. | Cancer science 20120501 |
Novel Cβ-Cγ bond cleavages of tryptophan-containing peptide radical cations. | Journal of the American Society for Mass Spectrometry 20120201 |
Activated CD69+ T cells foster immune privilege by regulating IDO expression in tumor-associated macrophages. | Journal of immunology (Baltimore, Md. : 1950) 20120201 |
IDO and regulatory T cell support are critical for cytotoxic T lymphocyte-associated Ag-4 Ig-mediated long-term solid organ allograft survival. | Journal of immunology (Baltimore, Md. : 1950) 20120101 |
The indoleamine 2,3-dioxygenase inhibitor 1-methyl-tryptophan suppresses mitochondrial function, induces aerobic glycolysis and decreases interleukin-10 production in human lymphocytes. | Immunological investigations 20120101 |
M. tuberculosis induces potent activation of IDO-1, but this is not essential for the immunological control of infection. | PloS one 20120101 |
Immunological and nonimmunological effects of indoleamine 2,3-dioxygenase on breast tumor growth and spontaneous metastasis formation. | Clinical & developmental immunology 20120101 |
Amelioration of 2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice by immunoregulatory dendritic cells. | Journal of gastroenterology 20111201 |
Indoleamine 2,3-dioxygenase expression in human cancers: clinical and immunologic perspectives. | Clinical cancer research : an official journal of the American Association for Cancer Research 20111115 |
Structure-activity relationship and enzyme kinetic studies on 4-aryl-1H-1,2,3-triazoles as indoleamine 2,3-dioxygenase (IDO) inhibitors. | European journal of medicinal chemistry 20111101 |
The role of indoleamine 2, 3-dioxygenase in lepromatous leprosy immunosuppression. | Clinical and experimental immunology 20110801 |
Contribution of dehydroepiandrosterone sulfate and progesterone to in vitro regulation of tolerogenic activity of IFN-α-induced dendritic cells. | Bulletin of experimental biology and medicine 20110601 |
Structure and reaction mechanism in the heme dioxygenases. | Biochemistry 20110412 |
Expression of indoleamine 2,3-dioxygenase in acute myeloid leukemia and the effect of its inhibition on cultured leukemia blast cells. | Medical oncology (Northwood, London, England) 20110301 |
A biological pathway linking inflammation and depression: activation of indoleamine 2,3-dioxygenase. | Neuropsychiatric disease and treatment 20110101 |
Peripheral anti-inflammatory effects explain the ginsenosides paradox between poor brain distribution and anti-depression efficacy. | Journal of neuroinflammation 20110101 |
Cnidarians as a source of new marine bioactive compounds--an overview of the last decade and future steps for bioprospecting. | Marine drugs 20110101 |
Suppression of humoral immune response to hepatitis B surface antigen vaccine in BALB/c mice by 1-methyl-tryptophan co-administration. | Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101 |
Indoleamine 2,3-dioxygenase-expressing leukemic dendritic cells impair a leukemia-specific immune response by inducing potent T regulatory cells. | Haematologica 20101201 |
Novel 1-alkyl-tryptophan derivatives downregulate IDO1 and IDO2 mRNA expression induced by interferon-gamma in dendritic cells. | Molecular and cellular biochemistry 20100901 |
Induction of indoleamine 2,3-dioxygenase by interferon-gamma in human lens epithelial cells: apoptosis through the formation of 3-hydroxykynurenine. | The international journal of biochemistry & cell biology 20100901 |
A combination of the metabolic enzyme inhibitor APO866 and the immune adjuvant L-1-methyl tryptophan induces additive antitumor activity. | Experimental biology and medicine (Maywood, N.J.) 20100701 |
The role of indoleamine 2,3-dioxygenase in retinal pigment epithelial cell-mediated immune modulation. | Ocular immunology and inflammation 20100101 |
Discrepancy between the in vitro and in vivo effects of murine mesenchymal stem cells on T-cell proliferation and collagen-induced arthritis. | Arthritis research & therapy 20100101 |
Role of 4-1BB receptor in the control played by CD8(+) T cells on IFN-gamma production by Mycobacterium tuberculosis antigen-specific CD4(+) T Cells. | PloS one 20100101 |
Divergent modulation of Chlamydia pneumoniae infection cycle in human monocytic and endothelial cells by iron, tryptophan availability and interferon gamma. | Immunobiology 20100101 |
Psychological stress-induced, IDO1-dependent tryptophan catabolism: implications on immunosuppression in mice and humans. | PloS one 20100101 |
Therapeutic potential of human umbilical cord mesenchymal stem cells in the treatment of rheumatoid arthritis. | Arthritis research & therapy 20100101 |
Role of the immunosuppressive enzyme indoleamine 2,3-dioxygenase in the progression of ovarian carcinoma. | Gynecologic oncology 20091101 |
IDO and outcomes in ovarian cancer. | Gynecologic oncology 20091101 |
Neuronal damage and protection in the pathophysiology and treatment of psychiatric illness: stress and depression. | Dialogues in clinical neuroscience 20090901 |
Efficacy of levo-1-methyl tryptophan and dextro-1-methyl tryptophan in reversing indoleamine-2,3-dioxygenase-mediated arrest of T-cell proliferation in human epithelial ovarian cancer. | Cancer research 20090701 |
Soluble mediators from mesenchymal stem cells suppress T cell proliferation by inducing IL-10. | Experimental & molecular medicine 20090531 |
Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice. | Molecular psychiatry 20090501 |
Allostimulatory activity of bone marrow-derived plasmacytoid dendritic cells is independent of indoleamine dioxygenase but regulated by inducible costimulator ligand expression. | Human immunology 20090501 |
Indoleamine 2,3 dioxygenase-mediated tryptophan catabolism regulates accumulation of Th1/Th17 cells in the joint in collagen-induced arthritis. | Arthritis and rheumatism 20090501 |
Induction of IDO by bacille Calmette-Guérin is responsible for development of murine depressive-like behavior. | Journal of immunology (Baltimore, Md. : 1950) 20090301 |
Substrate promiscuity of the cyclic dipeptide prenyltransferases from Aspergillus fumigatus ( section sign). | Journal of natural products 20090101 |
Kynurenine pathway metabolites in humans: disease and healthy States. | International journal of tryptophan research : IJTR 20090101 |
Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy. | The Biochemical journal 20080915 |
Synthesis of indoleamine 2,3-dioxygenase inhibitory analogues of the sponge alkaloid exiguamine A. | Journal of medicinal chemistry 20080508 |
Indoleamine 2,3-dioxygenase-dependent tryptophan metabolites contribute to tolerance induction during allergen immunotherapy in a mouse model. | The Journal of allergy and clinical immunology 20080401 |
Antimicrobial and immunoregulatory effects mediated by human lung cells: role of IFN-gamma-induced tryptophan degradation. | FEMS immunology and medical microbiology 20080301 |
Levo- but not dextro-1-methyl tryptophan abrogates the IDO activity of human dendritic cells. | Blood 20080215 |
Increased striatal serotonin synthesis following cortical resection in children with intractable epilepsy. | Epilepsy research 20080201 |
Uveal melanoma expression of indoleamine 2,3-deoxygenase: establishment of an immune privileged environment by tryptophan depletion. | Experimental eye research 20071101 |
Effect of Kidney-replenishing herb on the indoleamine 2,3-dioxygenase of human syncytiotrophoblasts cultured in vitro and the balance of helper T-cell cytokines. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20071101 |
Nitric oxide and indoleamine 2,3-dioxygenase mediate CTLA4Ig-induced survival in heart allografts in rats. | Transplantation 20071027 |
The blockade of T-cell co-stimulation as a therapeutic stratagem for immunosuppression: Focus on belatacept. | Biologics : targets & therapy 20070901 |
Indoleamine 2, 3-dioxygenase expression in cells of human acute monocyte leukemia (M(5)) and acute lymphocyte leukemia and therapeutic effect of its inhibitor 1-methyl tryptophan. | Zhongguo shi yan xue ye xue za zhi 20070601 |
IL-8 and IDO expression by human gingival fibroblasts via TLRs. | Journal of immunology (Baltimore, Md. : 1950) 20070115 |
Indoleamine 2,3-dioxygenase (IDO) is involved in promoting the development of anterior chamber-associated immune deviation. | Immunology letters 20061115 |
Hydrophobic effect and hydrogen bonds account for the improved activity of a complement inhibitor, compstatin. | Journal of medicinal chemistry 20060727 |
Inhibition of histidine ammonia lyase by heteroaryl-alanines and acrylates. | Chemistry & biodiversity 20060501 |
Influenza-induced expression of indoleamine 2,3-dioxygenase enhances interleukin-10 production and bacterial outgrowth during secondary pneumococcal pneumonia. | The Journal of infectious diseases 20060115 |
CD8 alpha+, but not CD8 alpha-, dendritic cells tolerize Th2 responses via contact-dependent and -independent mechanisms, and reverse airway hyperresponsiveness, Th2, and eosinophil responses in a mouse model of asthma. | Journal of immunology (Baltimore, Md. : 1950) 20050801 |
Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy. | Nature medicine 20050301 |
Interferon-gamma-modified dendritic cells suppress B cell function and ameliorate the development of experimental autoimmune myasthenia gravis. | Clinical and experimental immunology 20041101 |
4-1BB-mediated immunotherapy of rheumatoid arthritis. | Nature medicine 20041001 |
Indoleamine 2,3-dioxygenase activity and L-tryptophan transport in human breast cancer cells. | Biochimica et biophysica acta 20040210 |
Inhibition of indoleamine 2,3-dioxygenase suppresses NK cell activity and accelerates tumor growth. | Journal of experimental therapeutics & oncology 20030101 |
IDO (indolamine 2,3-dioxygenase) expression and function in the CNS. | Advances in experimental medicine and biology 20030101 |
Reproducing tna operon regulation in vitro in an S-30 system. Tryptophan induction inhibits cleavage of TnaC peptidyl-tRNA. | The Journal of biological chemistry 20010119 |
1-Methyl-DL-tryptophan, beta-(3-benzofuranyl)-DL-alanine (the oxygen analog of tryptophan), and beta-[3-benzo(b)thienyl]-DL-alanine (the sulfur analog of tryptophan) are competitive inhibitors for indoleamine 2,3-dioxygenase. | Archives of biochemistry and biophysics 19911201 |