Sesamin
| Title | Journal |
|---|---|
| Discovery of a sesamin-metabolizing microorganism and a new enzyme. | Proceedings of the National Academy of Sciences of the United States of America 20160809 |
| Sesamin ameliorates doxorubicin-induced cardiotoxicity: involvement of Sirt1 and Mn-SOD pathway. | Toxicology letters 20140113 |
| Zanthoxylum capense constituents with antimycobacterial activity against Mycobacterium tuberculosis in vitro and ex vivo within human macrophages. | Journal of ethnopharmacology 20130307 |
| Sesamin protects mouse liver against nickel-induced oxidative DNA damage and apoptosis by the PI3K-Akt pathway. | Journal of agricultural and food chemistry 20130206 |
| Comparison of metabolism of sesamin and episesamin by drug-metabolizing enzymes in human liver. | Drug metabolism and disposition: the biological fate of chemicals 20121001 |
| Sesamin modulates gene expression without corresponding effects on fatty acids in Atlantic salmon (Salmo salar L.). | Lipids 20120901 |
| (+)-Pinoresinol is a putative hypoglycemic agent in defatted sesame (Sesamum indicum) seeds though inhibiting α-glucosidase. | Bioorganic & medicinal chemistry letters 20120815 |
| Chondroprotective and anti-inflammatory effects of sesamin. | Phytochemistry 20120801 |
| Modulatory effects of sesamin on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells. | Neuropharmacology 20120601 |
| Tolbutamide hydroxylation by hepatic microsomes from Atlantic salmon (Salmo salar L.). | Molecular biology reports 20120601 |
| Quercetin and sesamin protect neuronal PC12 cells from high-glucose-induced oxidation, nitrosative stress, and apoptosis. | Rejuvenation research 20120601 |
| Plasma and tissue concentrations of α-tocopherol and δ-tocopherol following high dose dietary supplementation in mice. | Nutrients 20120601 |
| Sesamin exerts renoprotective effects by enhancing NO bioactivity in renovascular hypertensive rats fed with high-fat-sucrose diet. | European journal of pharmacology 20120515 |
| Anti-inflammatory and PPAR transactivational effects of secondary metabolites from the roots of Asarum sieboldii. | Bioorganic & medicinal chemistry letters 20120401 |
| How is sesamin metabolised in the human liver to show its biological effects? | Expert opinion on drug metabolism & toxicology 20120101 |
| Comparative effects of sesame seed lignan and flaxseed lignan in reducing the growth of human breast tumors (MCF-7) at high levels of circulating estrogen in athymic mice. | Nutrition and cancer 20120101 |
| [Anti-lipotoxic action of sesamin on renovascular hypertensive rats fed with a high-fat, high-sucrose diet]. | Yao xue xue bao = Acta pharmaceutica Sinica 20120101 |
| Sesamin stimulates osteoblast differentiation through p38 and ERK1/2 MAPK signaling pathways. | BMC complementary and alternative medicine 20120101 |
| Identification of the metabolites of episesamin in rat bile and human liver microsomes. | Biological & pharmaceutical bulletin 20120101 |
| Quercetin and sesamin protect dopaminergic cells from MPP+-induced neuroinflammation in a microglial (N9)-neuronal (PC12) coculture system. | Oxidative medicine and cellular longevity 20120101 |
| A phytochemical investigation of Zanthoxylum setulosum. | Natural product communications 20111201 |
| Sesamin induces melanogenesis by microphthalmia-associated transcription factor and tyrosinase up-regulation via cAMP signaling pathway. | Acta biochimica et biophysica Sinica 20111001 |
| Experimental antithrombotic effects of sesame seed whole grains and extracts. | Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20110901 |
| Sequential metabolism of sesamin by cytochrome P450 and UDP-glucuronosyltransferase in human liver. | Drug metabolism and disposition: the biological fate of chemicals 20110901 |
| Sesamin induces autophagy in colon cancer cells by reducing tyrosine phosphorylation of EphA1 and EphB2. | International journal of oncology 20110701 |
| Sesamin inhibits macrophage-induced vascular endothelial growth factor and matrix metalloproteinase-9 expression and proangiogenic activity in breast cancer cells. | Inflammation 20110601 |
| Involvement of heme oxygenase-1 induction via Nrf2/ARE activation in protection against H2O2-induced PC12 cell death by a metabolite of sesamin contained in sesame seeds. | Bioorganic & medicinal chemistry 20110315 |
| Genotoxicity evaluation of sesamin and episesamin. | Mutation research 20110203 |
| Influence of dietary sesamin, a bioactive compound on fatty acids and expression of some lipid regulating genes in Baltic Atlantic salmon (Salmo salar L.) juveniles. | Physiological research 20110101 |
| The mechanism underlying the synergetic hypocholesterolemic effect of sesamin and α-tocopherol in rats fed a high-cholesterol diet. | Journal of pharmacological sciences 20110101 |
| Sesamin ameliorates oxidative stress and mortality in kainic acid-induced status epilepticus by inhibition of MAPK and COX-2 activation. | Journal of neuroinflammation 20110101 |
| Fatty acids and gene expression responses to bioactive compounds in Atlantic salmon (Salmo salar L.) hepatocytes. | Neuro endocrinology letters 20110101 |
| Absolute configuration of antifibrotic (+)-episesamin isolated from Lindera obtusiloba BLUME. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20110101 |
| Metabolism of sesamin by cytochrome P450 in human liver microsomes. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
| Obtusilactone A and (-)-sesamin induce apoptosis in human lung cancer cells by inhibiting mitochondrial Lon protease and activating DNA damage checkpoints. | Cancer science 20101201 |
| A new 3,4-seco-lupane-type triterpenoid from the pulp of Acanthopanax senticosus (Rupr. et Maxim) Harms. | Natural product research 20101001 |
| Sesamin attenuates intercellular cell adhesion molecule-1 expression in vitro in TNF-alpha-treated human aortic endothelial cells and in vivo in apolipoprotein-E-deficient mice. | Molecular nutrition & food research 20100901 |
| Antioxidants from the leaves of Cinnamomum kotoense. | Natural product communications 20100601 |
| Sesamin manifests chemopreventive effects through the suppression of NF-kappa B-regulated cell survival, proliferation, invasion, and angiogenic gene products. | Molecular cancer research : MCR 20100501 |
| Sesquiterpenes from Oplopanax horridus. | Journal of natural products 20100423 |
| Specific dietary polyphenols attenuate atherosclerosis in apolipoprotein E-knockout mice by alleviating inflammation and endothelial dysfunction. | Arteriosclerosis, thrombosis, and vascular biology 20100401 |
| Sesamin attenuates behavioral, biochemical and histological alterations induced by reversible middle cerebral artery occlusion in the rats. | Chemico-biological interactions 20100105 |
| Angiogenic activity of sesamin through the activation of multiple signal pathways. | Biochemical and biophysical research communications 20100101 |
| Assessing the neuroprotective effect of antioxidant food factors by application of lipid-derived dopamine modification adducts. | Methods in molecular biology (Clifton, N.J.) 20100101 |
| Effects of dietary ingredients on function and expression of P-glycoprotein in human intestinal epithelial cells. | Biological & pharmaceutical bulletin 20100101 |
| Sesamin mitigates inflammation and oxidative stress in endothelial cells exposed to oxidized low-density lipoprotein. | Journal of agricultural and food chemistry 20091209 |
| Use of high resolution LC-MSn analysis in conjunction with mechanism-based stress studies: identification of asarinin, an impurity from sesame oil in an animal health product. | Journal of pharmaceutical and biomedical analysis 20091205 |
| Metabolic engineering of lignan biosynthesis in Forsythia cell culture. | Plant & cell physiology 20091201 |
| Antirejection effect of Herba Asari extract in rats after cardiac allograft implantation. | Transplantation proceedings 20091201 |
| Inhibition of 20-hydroxyeicosatetraenoic acid synthesis using specific plant lignans: in vitro and human studies. | Hypertension (Dallas, Tex. : 1979) 20091101 |
| Sesamin improves endothelial dysfunction in renovascular hypertensive rats fed with a high-fat, high-sucrose diet. | European journal of pharmacology 20091012 |
| Effects of a diet rich in sesame ( Sesamum indicum) pericarp on the expression of oestrogen receptor alpha and oestrogen receptor beta in rat prostate and uterus. | The British journal of nutrition 20090901 |
| Sesamin as a co-initiator for unfilled dental restorations. | Acta biomaterialia 20090901 |
| [Studies on the chemical constituents from Euphorbia chrysocoma]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090901 |
| Metabolites of sesamin, a major lignan in sesame seeds, induce neuronal differentiation in PC12 cells through activation of ERK1/2 signaling pathway. | Journal of neural transmission (Vienna, Austria : 1996) 20090701 |
| Effect of schisandrin B and sesamin mixture on CCl(4)-induced hepatic oxidative stress in rats. | Phytotherapy research : PTR 20090201 |
| Antihypertensive effects of sesamin in humans. | Journal of nutritional science and vitaminology 20090201 |
| Amides and benzenoids from Zanthoxylum ailanthoides with inhibitory activity on superoxide generation and elastase release by neutrophils. | Journal of natural products 20090101 |
| Assessing the neuroprotective effect of antioxidative food factors by application of lipid-derived dopamine modification adducts. | Methods in molecular biology (Clifton, N.J.) 20090101 |
| Effect of the form of the sesame-based diet on the absorption of lignans. | The British journal of nutrition 20081201 |
| Sesamin supplementation increases white muscle docosahexaenoic acid (DHA) levels in rainbow trout (Oncorhynchus mykiss) fed high alpha-linolenic acid (ALA) containing vegetable oil: metabolic actions. | Lipids 20081101 |
| Sesamin increases alpha-linolenic acid conversion to docosahexaenoic acid in atlantic salmon (Salmo salar L.) hepatocytes: role of altered gene expression. | Lipids 20081101 |
| First chemical synthesis of antioxidative metabolites of sesamin. | Chemical & pharmaceutical bulletin 20081101 |
| HPTLC fingerprinting and quantification of lignans as markers in sesame oil and its polyherbal formulations. | Journal of pharmaceutical and biomedical analysis 20080805 |
| Dietary tocotrienol reduces UVB-induced skin damage and sesamin enhances tocotrienol effects in hairless mice. | Journal of nutritional science and vitaminology 20080401 |
| Dietary sesamin suppresses aortic NADPH oxidase in DOCA salt hypertensive rats. | Clinical and experimental pharmacology & physiology 20080301 |
| Constituents of Asarum sieboldii with inhibitory activity on lipopolysaccharide (LPS)-induced NO production in BV-2 microglial cells. | Chemistry & biodiversity 20080201 |
| A survey of sesamin and composition of tocopherol variability from seeds of eleven diverse sesame (Sesamum indicum L.) genotypes using HPLC-PAD-ECD. | Phytochemical analysis : PCA 20080101 |
| Sesamin modulates tyrosine hydroxylase, superoxide dismutase, catalase, inducible NO synthase and interleukin-6 expression in dopaminergic cells under MPP+-induced oxidative stress. | Oxidative medicine and cellular longevity 20080101 |
| Trypanocidal and antileishmanial dihydrochelerythrine derivatives from Garcinia lucida. | Journal of natural products 20071001 |
| Sesamin, a lignan of sesame, down-regulates cyclin D1 protein expression in human tumor cells. | Cancer science 20070901 |
| Anti-inflammatory benzenoids from Antrodia camphorata. | Journal of natural products 20070601 |
| Suppression of ochratoxin biosynthesis by naturally occurring alkaloids. | Food additives and contaminants 20070401 |
| Comparative analysis of sesame lignans (sesamin and sesamolin) in affecting hepatic fatty acid metabolism in rats. | The British journal of nutrition 20070101 |
| An efficient and stereoselective dearylation of asarinin and sesamin tetrahydrofurofuran lignans to acuminatolide by methyltrioxorhenium/H(2)O(2) and UHP systems. | Journal of natural products 20070101 |
| Electrospray ionization ion-trap time-of-flight tandem mass spectrometry of two furofurans: sesamin and gmelinol. | Rapid communications in mass spectrometry : RCM 20070101 |
| Effect of sesamin on serum cholesterol and triglycerides levels in LDL receptor-deficient mice. | European journal of nutrition 20061201 |
| Sesamin metabolites induce an endothelial nitric oxide-dependent vasorelaxation through their antioxidative property-independent mechanisms: possible involvement of the metabolites in the antihypertensive effect of sesamin. | The Journal of pharmacology and experimental therapeutics 20060701 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Decomposition reaction of sesamin in supercritical water. | Bioscience, biotechnology, and biochemistry 20060501 |
| Dietary sesamin and docosahexaenoic and eicosapentaenoic acids synergistically increase the gene expression of enzymes involved in hepatic peroxisomal fatty acid oxidation in rats. | Metabolism: clinical and experimental 20060301 |
| Antioxidant activity and bioactive compounds of tea seed (Camellia oleifera Abel.) oil. | Journal of agricultural and food chemistry 20060208 |
| The epimerization of sesamin and asarinin. | Journal of natural products 20051101 |
| Sesamin ingestion regulates the transcription levels of hepatic metabolizing enzymes for alcohol and lipids in rats. | Alcoholism, clinical and experimental research 20051101 |
| NMR spectroscopic, mass spectroscopic, X-ray crystallographic, and theoretical studies of molecular mechanics of natural products: farformolide B and sesamin. | Biophysical chemistry 20050401 |
| Sesamin inhibits lipopolysaccharide-induced cytokine production by suppression of p38 mitogen-activated protein kinase and nuclear factor-kappaB. | Immunology letters 20050215 |
| Antioxidative catechol lignans converted from sesamin and sesaminol triglucoside by culturing with Aspergillus. | Journal of agricultural and food chemistry 20050112 |
| Effect of sesamin in Acanthopanax senticosus HARMS on behavioral dysfunction in rotenone-induced parkinsonian rats. | Biological & pharmaceutical bulletin 20050101 |
| Modulating effect of sesamin, a functional lignan in sesame seeds, on the transcription levels of lipid- and alcohol-metabolizing enzymes in rat liver: a DNA microarray study. | Bioscience, biotechnology, and biochemistry 20050101 |
| Sesamin induces nitric oxide and decreases endothelin-1 production in HUVECs: possible implications for its antihypertensive effect. | Journal of hypertension 20041201 |
| Effects of vitamin E and sesamin on hypertension and cerebral thrombogenesis in stroke-prone spontaneously hypertensive rats. | Clinical and experimental pharmacology & physiology 20041201 |
| Consumption of sesame oil muffins decreases the urinary excretion of gamma-tocopherol metabolites in humans. | Annals of the New York Academy of Sciences 20041201 |
| Dietary sesame oils inhibits iron-induced oxidative stress in rats [corrected]. | The British journal of nutrition 20041001 |
| Lignoids in insects: chemical probes for the study of ecdysis, excretion and Trypanosoma cruzi-triatomine interactions. | Toxicon : official journal of the International Society on Toxinology 20040915 |
| Protective effects of sesamin and sesamolin on murine BV-2 microglia cell line under hypoxia. | Neuroscience letters 20040826 |
| Antifungal constituents of Melicope borbonica. | Phytotherapy research : PTR 20040701 |
| Interaction of dietary fat types and sesamin on hepatic fatty acid oxidation in rats. | Biochimica et biophysica acta 20040601 |
| Insecticidal activity of chemical constituents from Aristolochia pubescens against Anticarsia gemmatalis larvae. | Pest management science 20040401 |
| Species differences in the physiological activity of dietary lignan (sesamin and episesamin) in affecting hepatic fatty acid metabolism. | The British journal of nutrition 20040301 |
| Free radical scavenging behavior of antioxidant compounds of sesame (sesamum indicum L.) in DPPH(*) system. | Journal of agricultural and food chemistry 20040225 |
| Antioxidative roles of sesamin, a functional lignan in sesame seed, and it's effect on lipid- and alcohol-metabolism in the liver: a DNA microarray study. | BioFactors (Oxford, England) 20040101 |
| Effects of sesamin on aortic oxidative stress and endothelial dysfunction in deoxycorticosterone acetate-salt hypertensive rats. | Biological & pharmaceutical bulletin 20031201 |
| Effects of sesamin and capsaicin on the mRNA expressions of delta6 and delta5 desaturases in rat primary cultured hepatocytes. | Journal of nutritional science and vitaminology 20031201 |
| Protective effect of sesamin administration on exercise-induced lipid peroxidation. | International journal of sports medicine 20031001 |
| Protective effects of sesamin and sesamolin on hypoxic neuronal and PC12 cells. | Journal of neuroscience research 20031001 |
| Effect of dietary fat level and sesamin on the polyunsaturated fatty acid metabolism in rats. | Journal of nutritional science and vitaminology 20031001 |
| Dietary sesame lignans decrease lipid peroxidation in rats fed docosahexaenoic acid. | Journal of nutritional science and vitaminology 20030801 |
| Antifungal and antioxidant compounds from the root bark of Fagara zanthoxyloides. | Planta medica 20030401 |
| Novel antioxidative metabolites in rat liver with ingested sesamin. | Journal of agricultural and food chemistry 20030312 |
| Antioxidant and anti-inflammatory effects of a diet supplemented with sesamin on hepatic ischemia-reperfusion injury in rats. | Hepato-gastroenterology 20030101 |
| Combined effects of dietary conjugated linoleic acid and sesamin triacylglycerol and ketone body production in rat liver. | Journal of nutritional science and vitaminology 20021001 |
| Antihypertensive effect of sesamin. IV. Inhibition of vascular superoxide production by sesamin. | Biological & pharmaceutical bulletin 20020901 |
| Determination of L-sesamin and L-asarinin in Zanthoxylum(Roxb.) DC. by high performance liquid chromatography. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20020701 |
| Short and stereoselective total synthesis of furano lignans (+/-)-dihydrosesamin, (+/-)-lariciresinol dimethyl ether, (+/-)-acuminatin methyl ether, (+/-)-sanshodiol methyl ether, (+/-)-lariciresinol, (+/-)-acuminatin, and (+/-)-lariciresinol monomethyl ether and furofuran lignans (+/-)-sesamin, (+/-)-eudesmin, (+/-)-piperitol methyl ether, (+/-)-pinoresinol, (+/-)-piperitol, and (+/-)-pinoresinol monomethyl ether by radical cyclization of epoxides using a transition-metal radical source. | The Journal of organic chemistry 20020517 |
| Sesamin, a sesame lignan, decreases fatty acid synthesis in rat liver accompanying the down-regulation of sterol regulatory element binding protein-1. | Biochimica et biophysica acta 20011130 |
| Effects of vitamin E and sesamin on hypertension and cerebral thrombogenesis in stroke-prone spontaneously hypertensive rats. | Hypertension research : official journal of the Japanese Society of Hypertension 20011101 |
| Dietary manipulations of body fat-reducing potential of conjugated linoleic acid in rats. | Bioscience, biotechnology, and biochemistry 20011101 |
| C-H insertion approach to the synthesis of endo,exo-furofuranones: synthesis of (+/-)-asarinin, (+/-)-epimagnolin A, and (+/-)-fargesin. | The Journal of organic chemistry 20011005 |
| Effect of sesame seeds rich in sesamin and sesamolin on fatty acid oxidation in rat liver. | Journal of agricultural and food chemistry 20010501 |
| Effect of sesamin on mitochondrial and peroxisomal beta-oxidation of arachidonic and eicosapentaenoic acids in rat liver. | Lipids 20010501 |
| [Studies on the chemical constituents of the herba of Cuscuta chinensis]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20010501 |
| Sesamin a potent antifeedant principle from Piper mullesua. | Phytotherapy research : PTR 20010201 |
| Effects of dietary sesame seeds on plasma tocopherol levels. | Nutrition and cancer 20010101 |
| Separation and NMR studies on lignans of Raulinoa echinata. | Phytochemical analysis : PCA 20010101 |
| Differential in vitro anti-HIV activity of natural lignans. | Zeitschrift fur Naturforschung. C, Journal of biosciences 19900101 |