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D-Cystine

CAS No.:
349-46-2
Catalog Number:
AG0037D9
Molecular Formula:
C6H12N2O4S2
Molecular Weight:
240.3005
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
98%
In Stock USA
United States
$13
- +
5g
98%
In Stock USA
United States
$25
- +
25g
98%
In Stock USA
United States
$63
- +
100g
98%
In Stock USA
United States
$125
- +
500g
98%
In Stock USA
United States
$500
- +
Product Description
Catalog Number:
AG0037D9
Chemical Name:
D-Cystine
CAS Number:
349-46-2
Molecular Formula:
C6H12N2O4S2
Molecular Weight:
240.3005
MDL Number:
MFCD00002610
IUPAC Name:
(2S)-2-amino-3-[[(2S)-2-amino-2-carboxyethyl]disulfanyl]propanoic acid
InChI:
InChI=1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m1/s1
InChI Key:
LEVWYRKDKASIDU-QWWZWVQMSA-N
SMILES:
N[C@@H](C(=O)O)CSSC[C@H](C(=O)O)N
UNII:
KX1RHN0Y0B
Properties
Complexity:
192  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
0
Exact Mass:
240.024g/mol
Formal Charge:
0
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0
Molecular Weight:
240.292g/mol
Monoisotopic Mass:
240.024g/mol
Rotatable Bond Count:
7  
Topological Polar Surface Area:
177A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-6.3  
Literature
Title Journal
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Increased disulphide dimer formation of latent associated peptide fusions of TGF-β by addition of L-cystine. Journal of biotechnology 20121031
The role of disulfide bond formation in the structural transition observed in the intermediate filaments of developing hair. Journal of structural biology 20121001
The cystine/glutamate antiporter regulates the functional expression of indoleamine 2,3-dioxygenase in human dendritic cells. Scandinavian journal of immunology 20121001
Suppository formulations as a potential treatment for nephropathic cystinosis. Journal of pharmaceutical sciences 20121001
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A chelating-bond breaking and re-linking technique for rapid re-immobilization of immune micro-sensors. Biomedical microdevices 20120401
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Plasma biomarkers of oxidative stress and genetic variants in age-related macular degeneration. American journal of ophthalmology 20120301
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Rotational and hinge dynamics of discoidal high density lipoproteins probed by interchain disulfide bond formation. Biochimica et biophysica acta 20120301
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Good neighbours in the tumour stroma reduce oxidative stress. Nature cell biology 20120219
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The TM2 6' position of GABA(A) receptors mediates alcohol inhibition. The Journal of pharmacology and experimental therapeutics 20120201
Self-organization at the interface and in aqueous solution of a cationic gemini surfactant from the dioctyl ester of cystine. Journal of colloid and interface science 20120201
Crystal structures of two solute receptors for L-cystine and L-cysteine, respectively, of the human pathogen Neisseria gonorrhoeae. Journal of molecular biology 20120120
Clinical, biochemical and molecular characterization of cystinuria in a cohort of 12 patients. Clinical genetics 20120101
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System xc⁻ cystine/glutamate antiporter: an update on molecular pharmacology and roles within the CNS. British journal of pharmacology 20120101
The progranulin (GRN) Cys157LysfsX97 mutation is associated with nonfluent variant of primary progressive aphasia clinical phenotype. Journal of Alzheimer's disease : JAD 20120101
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New insights into the metabolism of organomercury compounds: mercury-containing cysteine S-conjugates are substrates of human glutamine transaminase K and potent inactivators of cystathionine γ-lyase. Archives of biochemistry and biophysics 20120101
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Stem cell microvesicles transfer cystinosin to human cystinotic cells and reduce cystine accumulation in vitro. PloS one 20120101
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Preventing metal-mediated oxidative DNA damage with selenium compounds. Metallomics : integrated biometal science 20110501
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Unraveling the mechanism of β-N-oxalyl-α,β-diaminopropionic acid (β-ODAP) induced excitotoxicity and oxidative stress, relevance for neurolathyrism prevention. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110301
Glutamate preferentially suppresses osteoblastogenesis than adipogenesis through the cystine/glutamate antiporter in mesenchymal stem cells. Journal of cellular physiology 20110301
Brain glutathione as a target for aetiological factors in neurolathyrism and konzo. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110301
Generation of the oxidized form protects human brain type creatine kinase against cystine-induced inactivation. International journal of biological macromolecules 20110301
Computational analysis and structure predictions of CHH-related peptides from Litopenaeus vannamei. Integrative biology : quantitative biosciences from nano to macro 20110301
[Determination of sulfur amino acids in feedstuffs by high performance liquid chromatography coupled with pre-column derivatization]. Se pu = Chinese journal of chromatography 20110301
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Cysteine/cystine redox signaling in cardiovascular disease. Free radical biology & medicine 20110215
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Dietary sulfur amino acid effects on fasting plasma cysteine/cystine redox potential in humans. Nutrition (Burbank, Los Angeles County, Calif.) 20110201
Cystine-mediated oligomerization of the Atlantic salmon serum C-type lectin. Biochimica et biophysica acta 20110201
Distinct second extracellular loop structures of the brain cannabinoid CB(1) receptor: implication in ligand binding and receptor function. Proteins 20110201
Lobeline and cytisine reduce voluntary ethanol drinking behavior in male C57BL/6J mice. Progress in neuro-psychopharmacology & biological psychiatry 20110115
Intramolecular azo-bridge as a cystine disulfide bond surrogate: Somatostatin-14 and brain natriuretic peptide (BNP) analogs. Bioorganic & medicinal chemistry 20110115
Dissection of mitogenic and neurodegenerative actions of cystine and glutamate in malignant gliomas. Oncogene 20110106
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A negative correlation between expression profiles of runt-related transcription factor-2 and cystine/glutamate antiporter xCT subunit in ovariectomized mouse bone. Journal of pharmacological sciences 20110101
Application of XANES profiles to X-ray spectromicroscopy for biomedical specimens: Part I. Discrimination of macromolecules with sulfur atoms. Journal of X-ray science and technology 20110101
Matrix-assisted laser desorption/ionization-post source decay fragmentation of cystine- containing amphibian peptides with novel cysteine tags. European journal of mass spectrometry (Chichester, England) 20110101
Increased expression of cystine/glutamate antiporter in multiple sclerosis. Journal of neuroinflammation 20110101
Direct determination of ECD in ECD Kit: a solid sample quantitation method for active pharmaceutical ingredient in drug product. Journal of biomedicine & biotechnology 20110101
Plasma L-cystine/L-glutamate imbalance increases tumor necrosis factor-alpha from CD14+ circulating monocytes in patients with advanced cirrhosis. PloS one 20110101
Quantitative in vivo and ex vivo confocal microscopy analysis of corneal cystine crystals in the Ctns knockout mouse. Molecular vision 20110101
Optimized method for determining free L-cysteine in rat plasma by high-performance liquid chromatography with the 4-aminosulfonyl-7-fluoro-2,1,3-benzoxadiazole conversion reagent. Bioscience, biotechnology, and biochemistry 20110101
Evaluation of topical cysteamine therapy in the CTNS(-/-) knockout mouse using in vivo confocal microscopy. Molecular vision 20110101
Population pharmacokinetics and pharmacodynamics of cysteamine in nephropathic cystinosis patients. Orphanet journal of rare diseases 20110101
Functionalization of sol gel bioactive glasses carrying Au nanoparticles: selective Au affinity for amino and thiol ligand groups. Langmuir : the ACS journal of surfaces and colloids 20101221
Predicting the state of cysteines based on sequence information. Journal of theoretical biology 20101207
Conformational characterization of disulfide bonds: a tool for protein classification. Journal of theoretical biology 20101207
Absorption and metabolization of cytoprotective epicatechin thio conjugates in rats. Drug metabolism and disposition: the biological fate of chemicals 20101201
The incidence of atubular glomeruli in nephropathic cystinosis renal biopsies. Molecular genetics and metabolism 20101201
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Regulation of system x(c)(-)activity and expression in astrocytes by interleukin-1β: implications for hypoxic neuronal injury. Glia 20101115
Fast cleavage of a diselenide induced by a platinum(II)-methionine complex and its biological implications. Journal of inorganic biochemistry 20101101
The pathogenesis of cystinosis: mechanisms beyond cystine accumulation. American journal of physiology. Renal physiology 20101101
Medicine. Stopping the stones. Science (New York, N.Y.) 20101015
Crystal growth inhibitors for the prevention of L-cystine kidney stones through molecular design. Science (New York, N.Y.) 20101015
The kinetics of β-elimination of cystine and the formation of lanthionine in gliadin. Journal of agricultural and food chemistry 20101013
N-acetylcysteine improves hemodynamics and reduces oxidative stress in the brains of newborn piglets with hypoxia-reoxygenation injury. Journal of neurotrauma 20101001
Simultaneous analysis of mercury and selenium species including chiral forms of selenomethionine in human urine and serum by HPLC column-switching coupled to ICP-MS. The Analyst 20101001
The cystine/glutamate antiporter regulates dendritic cell differentiation and antigen presentation. Journal of immunology (Baltimore, Md. : 1950) 20100915
Matrix metalloproteinase 9 targeting peptides: syntheses, 68Ga-labeling, and preliminary evaluation in a rat melanoma xenograft model. Bioconjugate chemistry 20100915
Role of the intra-A-chain disulfide bond of insulin-like peptide 3 in binding and activation of its receptor, RXFP2. Peptides 20100901
Topology of the disulfide bonds in the antiviral lectin scytovirin. Protein science : a publication of the Protein Society 20100901
Effects of a novel cystine-based glutathione precursor on oxidative stress in vascular smooth muscle cells. American journal of physiology. Cell physiology 20100901
The effect of chitosan as internal or external coating on the 5-ASA release from calcium alginate microparticles. AAPS PharmSciTech 20100901
Altered ferritin subunit composition: change in iron metabolism in lens epithelial cells and downstream effects on glutathione levels and VEGF secretion. Investigative ophthalmology & visual science 20100901
A-Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance--part 12. British journal of sports medicine 20100901
Transcriptional profiles for glutamate transporters reveal differences between organophosphates but similarities with unrelated neurotoxicants. Brain research bulletin 20100830
Dissociation of copper(II) ternary complexes containing cystine. Physical chemistry chemical physics : PCCP 20100821
Experimental and computational thermochemical study of sulfur-containing amino acids: L-cysteine, L-cystine, and L-cysteine-derived radicals. S-S, S-H, and C-S bond dissociation enthalpies. The journal of physical chemistry. B 20100819
Histidine, cystine, glutamine, and threonine collectively protect astrocytes from the toxicity of zinc. Free radical biology & medicine 20100815
Characterization of apical and basal thiol-disulfide redox regulation in human colonic epithelial cells. American journal of physiology. Gastrointestinal and liver physiology 20100801
Determination of renal stone composition with dual-energy computed tomography: an emerging application. Seminars in ultrasound, CT, and MR 20100801
Tissue factor mutated at the allosteric Cys186-Cys209 disulfide bond is severely impaired in decrypted procoagulant activity. Blood 20100722
A phase I study of imexon plus gemcitabine as first-line therapy for advanced pancreatic cancer. Cancer chemotherapy and pharmacology 20100701
Mechanisms of oxidative glutamate toxicity: the glutamate/cystine antiporter system xc- as a neuroprotective drug target. CNS & neurological disorders drug targets 20100701
Analysis of 24-hour urine parameters as it relates to age of onset of cystine stone formation. Journal of endourology 20100701
Development of a rapid and sensitive method for determination of cysteine/cystine ratio in chemically defined media. Journal of chromatography. A 20100611
Oxidation of plasma cysteine/cystine and GSH/GSSG redox potentials by acetaminophen and sulfur amino acid insufficiency in humans. The Journal of pharmacology and experimental therapeutics 20100601
Growth retardation in children with cystinosis. Minerva pediatrica 20100601
Downregulation of cystine transporter xc by irinotecan in human head and neck cancer FaDu xenografts. Chemotherapy 20100601
Features of a spatially constrained cystine loop in the p10 FAST protein ectodomain define a new class of viral fusion peptides. The Journal of biological chemistry 20100528
Cystine 186-cystine 209 disulfide bond is not essential for the procoagulant activity of tissue factor or for its de-encryption. Blood 20100527
Synthesis of unnatural selenocystines and beta-aminodiselenides via regioselective ring-opening of sulfamidates using a sequential, one-pot, multistep strategy. The Journal of organic chemistry 20100507
Long-term treatment of cystinosis in children with twice-daily cysteamine. The Journal of pediatrics 20100501
Local hindlimb antioxidant infusion does not affect muscle glucose uptake during in situ contractions in rat. Journal of applied physiology (Bethesda, Md. : 1985) 20100501
N-Acetylcysteine infusion does not affect glucose disposal during prolonged moderate-intensity exercise in humans. The Journal of physiology 20100501
The pleiotropic CymR regulator of Staphylococcus aureus plays an important role in virulence and stress response. PLoS pathogens 20100501
Structure-activity relationships in toll-like receptor-2 agonistic diacylthioglycerol lipopeptides. Journal of medicinal chemistry 20100422
Fertility status in male cystinosis patients treated with cysteamine. Fertility and sterility 20100401
Cysteine, thiourea and thiocyanate interactions with clays: FT-IR, Mössbauer and EPR spectroscopy and X-ray diffractometry studies. Amino acids 20100401
Renal phenotype of the cystinosis mouse model is dependent upon genetic background. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100401
Arsenic accumulation and thiol status in lichens exposed to As(V) in controlled conditions. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20100401
Mouse cumulus-denuded oocytes restore developmental capacity completely when matured with optimal supplementation of cysteamine, cystine, and cumulus cells. Biology of reproduction 20100401
Inhibition of apoptotic signalling in spermine-treated vascular smooth muscle cells by a novel glutathione precursor. Cell biology international 20100401
Lactacidosis modulates glutathione metabolism and oxidative glutamate toxicity. Journal of neurochemistry 20100401
Site-specific effects of diselenide bridges on the oxidative folding of a cystine knot peptide, omega-selenoconotoxin GVIA. Biochemistry 20100330
Pharmacogenomic approach reveals a role for the x(c)- cystine/glutamate antiporter in growth and celastrol resistance of glioma cell lines. The Journal of pharmacology and experimental therapeutics 20100301
Potential mechanisms involved in the absorptive transport of cadmium in isolated perfused rabbit renal proximal tubules. Toxicology letters 20100301
Analysis of 13Calpha and 13Cbeta chemical shifts of cysteine and cystine residues in proteins: a quantum chemical approach. Journal of biomolecular NMR 20100301
Cystine and theanine supplementation restores high-intensity resistance exercise-induced attenuation of natural killer cell activity in well-trained men. Journal of strength and conditioning research 20100301
'Relaxers' damage hair: evidence from amino acid analysis. Journal of the American Academy of Dermatology 20100301
Commentary: healthy hair and protein loss. Journal of the American Academy of Dermatology 20100301
Antioxidant micronutrients and biomarkers of oxidative stress and inflammation in colorectal adenoma patients: results from a randomized, controlled clinical trial. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20100301
Formation of pyrazines in Maillard model systems of lysine-containing dipeptides. Journal of agricultural and food chemistry 20100224
Small-molecule diselenides catalyze oxidative protein folding in vivo. ACS chemical biology 20100219
Cysteine and glutathione mixed-disulfide conjugates of thiosulfinates: chemical synthesis and biological activities. Journal of agricultural and food chemistry 20100210
Developmental changes in cerebral white matter microstructure in a disorder of lysosomal storage. Cortex; a journal devoted to the study of the nervous system and behavior 20100201
A novel murine model for chronic inflammatory alveolar bone loss. Journal of periodontal research 20100201
Combined administration of (L)-cystine and (L)-theanine enhances immune functions and protects against influenza virus infection in aged mice. The Journal of veterinary medical science 20100201
The DC gate in Channelrhodopsin-2: crucial hydrogen bonding interaction between C128 and D156. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20100201
Potent homocysteine-induced ERK phosphorylation in cultured neurons depends on self-sensitization via system Xc(-). Toxicology and applied pharmacology 20100115
A key role for mitochondria in endothelial signaling by plasma cysteine/cystine redox potential. Free radical biology & medicine 20100115
Evaluation of trends in urolith composition and characteristics of dogs with urolithiasis: 25,499 cases (1985-2006). Journal of the American Veterinary Medical Association 20100115
Polarized spectroscopic elucidation of N-acetyl-L-cysteine, L-cysteine, L-cystine, L-ascorbic acid and a tool for their determination in solid mixtures. Amino acids 20100101
Self-assembling and auto-crosslinkable hyaluronic acid hydrogels with a fibrillar structure. Acta biomaterialia 20100101
Lupin protein isolate and cysteine-supplemented casein reduce calcification of atherosclerotic lesions in apoE-deficient mice. The British journal of nutrition 20100101
Ceftriaxone restores glutamate homeostasis and prevents relapse to cocaine seeking. Biological psychiatry 20100101
Identification of human calculi with time-of-flight secondary ion mass spectrometry. Rapid communications in mass spectrometry : RCM 20100101
Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystine and cysteine. Cancer research 20100101
Non-type I cystinuria associated with mental retardation and ataxia in a Korean boy with a new missence mutation(G173R) in the SLC7A9 gene. Journal of Korean medical science 20100101
Comparison of the effects on lipid metabolism of dietary methionine and cystine between hepatoma-bearing and normal rats. Bioscience, biotechnology, and biochemistry 20100101
Technetium-99m ethyl cysteinate dimer (ECD) cerebral accumulation and symptom and sign severity during hypothyroidism. Neuro endocrinology letters 20100101
Evaluation of nondigested carbohydrates in hydroxypropylated tapioca starch. Journal of food science 20100101
An update and practical guide to renal stone management. Nephron. Clinical practice 20100101
Effects of simultaneous dietary fish oil ingestion and sulfur amino acid supplementation on the lipid metabolism in hepatoma-bearing rats with hyperlipidemia. Journal of nutritional science and vitaminology 20100101
Perfluorooctanoic acid for shotgun proteomics. PloS one 20100101
Regulation of interleukin-4 signaling by extracellular reduction of intramolecular disulfides. Biochemical and biophysical research communications 20091225
Molecularly defined antibody conjugation through a selenocysteine interface. Biochemistry 20091222
Multiple screening of urolithic organic acids with copper nanoparticle-plated electrode: potential assessment of urolithic risks. Analytical biochemistry 20091215
Extracellular redox status regulates Nrf2 activation through mitochondrial reactive oxygen species. The Biochemical journal 20091210
Time before isolating cystinotic leukocytes affects reliability of cystine determination. Pediatric nephrology (Berlin, Germany) 20091201
Cysteamine prevents inhibition of adenylate kinase caused by cystine in rat brain cortex. Metabolic brain disease 20091201
Trichothiodystrophy and fragile hair: the distinction between diagnostic signs and diagnostic labels in childhood hair disease. The British journal of dermatology 20091201
Quiz page. Fanconi syndrome caused by cystinosis, intermediate type. American journal of kidney diseases : the official journal of the National Kidney Foundation 20091201
Nicotinic receptor ligands reduce ethanol intake by high alcohol-drinking HAD-2 rats. Alcohol (Fayetteville, N.Y.) 20091201
The platelet receptor CLEC-2 is active as a dimer. Biochemistry 20091124
Identification of specific transmembrane residues and ligand-induced interface changes involved in homo-dimer formation of a yeast G protein-coupled receptor. Biochemistry 20091124
Measuring the poise of thiol/disulfide couples in vivo. Free radical biology & medicine 20091115
Engineered cystine knot peptides that bind alphavbeta3, alphavbeta5, and alpha5beta1 integrins with low-nanomolar affinity. Proteins 20091101
Investigating the influences of redox buffer compositions on the amyloid fibrillogenesis of hen egg-white lysozyme. Biochimica et biophysica acta 20091101
Electrochemical oxidation of selenocystine and selenomethionine. Colloids and surfaces. B, Biointerfaces 20091101
In vitro radioprotection studies of organoselenium compounds: differences between mono- and diselenides. Radiation and environmental biophysics 20091101
High-dose cysteine administration does not increase synthesis of the antioxidant glutathione preterm infants. Pediatrics 20091101
The biological activity and metabolic stability of peptidic bifunctional compounds that are opioid receptor agonists and neurokinin-1 receptor antagonists with a cystine moiety. Bioorganic & medicinal chemistry 20091015
Facile syntheses of L-beta-haloalanine derivatives from L-cysteine or L-cystine. Amino acids 20091001
Estimation of urinary stone composition by automated processing of CT images. Urological research 20091001
Cystinosis of the brain and spinal cord with associated vasculopathy. Journal of the neurological sciences 20090915
Gemini surfactant-protein interactions: effect of pH, temperature, and surfactant stereochemistry. Biomacromolecules 20090914
Evaluation of treatment with cysteamine eyedrops for cystinosis with confocal microscopy. Cornea 20090901
Cysteamine prevents inhibition of adenylate kinase caused by cystine in rat brain cortex. Metabolic brain disease 20090901
[Fluorescence analysis of trace glucose using glucose oxidase and horseradish peroxidase]. Guang pu xue yu guang pu fen xi = Guang pu 20090901
Burn injury induces the expression of cystine/glutamate transporter (x(c)(-)) in mouse T cells. Immunology letters 20090815
The xc- cystine/glutamate antiporter as a potential therapeutic target for small-cell lung cancer: use of sulfasalazine. Cancer chemotherapy and pharmacology 20090801
The x(c)(-) cystine/glutamate antiporter (xCT) as a potential target for therapy of cancer: yet another cytotoxic anticancer approach? Journal of cellular physiology 20090801
Stereoselective HDAC inhibition from cysteine-derived zinc-binding groups. ChemMedChem 20090801
Current medical aspects of pantethine. Ideggyogyaszati szemle 20090730
Use of the design-of-experiments approach for the development of a refolding technology for progenipoietin-1, a recombinant human cytokine fusion protein from Escherichia coli inclusion bodies. Biotechnology and applied biochemistry 20090714
No selenium required: reactions catalyzed by mammalian thioredoxin reductase that are independent of a selenocysteine residue. Biochemistry 20090707
CymR, the master regulator of cysteine metabolism in Staphylococcus aureus, controls host sulphur source utilization and plays a role in biofilm formation. Molecular microbiology 20090701
Elucidating conformational changes in the gamma-aminobutyric acid transporter-1. The Journal of biological chemistry 20090612
Cystine accumulation in the CNS results in severe age-related memory deficits. Neurobiology of aging 20090601
Peroxynitrite elevation in exhaled breath condensate of COPD and its inhibition by fudosteine. Chest 20090601
Laser capture microscopy in a study of expression of structural proteins in the cuticle cells of human hair. Experimental dermatology 20090601
beta-N-methylamino-l-alanine induces oxidative stress and glutamate release through action on system Xc(-). Experimental neurology 20090601
Theoretical and experimental sulfur K-edge X-ray absorption spectroscopic study of cysteine, cystine, homocysteine, penicillamine, methionine and methionine sulfoxide. Dalton transactions (Cambridge, England : 2003) 20090514
Evidence for durable kidney stone prevention over several decades. BJU international 20090501
Study of the oxidation dynamics of ethyl cysteinate dimer in solution by ultra-performance liquid chromatography with tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20090501
In vivo confocal microscopy and anterior segment optical coherence tomography analysis of the cornea in nephropathic cystinosis. Ophthalmology 20090501
Tardive dyskinesia and DRD3, HTR2A and HTR2C gene polymorphisms in Russian psychiatric inpatients from Siberia. Progress in neuro-psychopharmacology & biological psychiatry 20090430
Effects of oral supplementation with cystine and theanine on the immune function of athletes in endurance exercise: randomized, double-blind, placebo-controlled trial. Bioscience, biotechnology, and biochemistry 20090423
Molecular evolution of cystine-stabilized miniproteins as stable proteinaceous binders. Structure (London, England : 1993) 20090415
Novel dimerization mode of the human Bcl-2 family protein Bak, a mitochondrial apoptosis regulator. Journal of structural biology 20090401
Pseudo-merohedral twinning in monoclinic crystals of wild-type human brain neuroglobin. Acta crystallographica. Section D, Biological crystallography 20090401
SPECT and PET imaging of EGF receptors with site-specifically labeled EGF and dimeric EGF. Bioconjugate chemistry 20090401
Methionine+cystine requirement of broiler chickens fed low-density diets under tropical conditions. Tropical animal health and production 20090301
Selenocystine induces caspase-independent apoptosis in MCF-7 human breast carcinoma cells with involvement of p53 phosphorylation and reactive oxygen species generation. The international journal of biochemistry & cell biology 20090301
Interactions of the M. tuberculosis UsfX with the cognate sigma factor SigF and the anti-anti sigma factor RsfA. Biochimica et biophysica acta 20090301
Comparative evaluation of Tc-99m cystine and Tc-99m MAG3 in normals and patients with renal functional impairment. Clinical nuclear medicine 20090301
The role of copper in cysteine oxidation: study of intra- and inter-molecular reactions in mass spectrometry. Metallomics : integrated biometal science 20090301
Computational model of extracellular glutamate in the nucleus accumbens incorporates neuroadaptations by chronic cocaine. Neuroscience 20090218
Selenocystine induces reactive oxygen species-mediated apoptosis in human cancer cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090201
HMOX1 and NQO1 genes are upregulated in response to contact sensitizers in dendritic cells and THP-1 cell line: role of the Keap1/Nrf2 pathway. Toxicological sciences : an official journal of the Society of Toxicology 20090201
N,N'-Bis(5-aminosalicyl)-L-cystine is a potential colon-specific 5-aminosalicylic acid prodrug with dual therapeutic effects in experimental colitis. Journal of pharmaceutical sciences 20090101
Oxidation of plasma cysteine/cystine redox state in endotoxin-induced lung injury. American journal of respiratory cell and molecular biology 20090101
Oxidation of extracellular cysteine/cystine redox state in bleomycin-induced lung fibrosis. American journal of physiology. Lung cellular and molecular physiology 20090101
Changing paradigms in diagnosis of inherited defects associated with urolithiasis. The Veterinary clinics of North America. Small animal practice 20090101
Non-contact anterior segment OCT for corneal crystals in cystinosis. Journal of pediatric ophthalmology and strabismus 20090101
Prolonged treatment with N-acetylcystine delays liver recovery from acetaminophen hepatotoxicity. Critical care (London, England) 20090101
Intestinal barrier function in response to abundant or depleted mucosal glutathione in Salmonella-infected rats. BMC physiology 20090101
Retrocyclin-2: a potent anti-HIV theta-defensin that forms a cyclic cystine ladder structural motif. Advances in experimental medicine and biology 20090101
Role of N-acetylcysteine and cystine in glutathione synthesis in human erythrocytes. Redox report : communications in free radical research 20090101
Intestinal redox status of major intracellular thiols in a rat model of chronic alcohol consumption. JPEN. Journal of parenteral and enteral nutrition 20090101
[Hypothesis of biochemical mechanisms of kidney calculi formation]. Urologiia (Moscow, Russia : 1999) 20090101
Enzymatic approach to analyze the effects of mercaptans on hair. Journal of cosmetic science 20090101
Novel fluorescence molecular imaging of chemotherapy-induced intestinal apoptosis. Journal of biomedical optics 20090101
Mechanisms of beta-N-methylamino-L-alanine induced neurotoxicity. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20090101
Cystinosis, Fanconi syndrome, and odontogenic cysts. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20081201
Co-administration of l-cystine and l-theanine enhances efficacy of influenza vaccination in elderly persons: nutritional status-dependent immunogenicity. Geriatrics & gerontology international 20081201
Reversible dynamic isomerism change in the solid state, from Bi4I16 clusters to BiI4 1D chains in L-cystine based hybrids: templating effect of cations in iodobismuthate network formation. Chemical communications (Cambridge, England) 20081130
Selenocystine induces S-phase arrest and apoptosis in human breast adenocarcinoma MCF-7 cells by modulating ERK and Akt phosphorylation. Journal of agricultural and food chemistry 20081126
Effect of fudosteine on mucin production. The European respiratory journal 20081101
Is ascorbate able to reduce disulfide bridges? A cautionary note. Nitric oxide : biology and chemistry 20081101
A novel approach to enhancing cellular glutathione levels. Journal of neurochemistry 20081101
The three-fingered protein domain of the human genome. Cellular and molecular life sciences : CMLS 20081101
Effect of dimethyl sulfides on the induction of apoptosis in human leukemia Jurkat cells and HL-60 cells. Bioscience, biotechnology, and biochemistry 20081101
Clinicopathological features of ocular cystinosis. Clinical & experimental ophthalmology 20081101
Urinary felinine excretion in intact male cats is increased by dietary cystine. The British journal of nutrition 20081001
A rapid LC-FTMS method for the analysis of cysteine, cystine and cysteine/cystine steady-state redox potential in human plasma. Clinica chimica acta; international journal of clinical chemistry 20081001
Repeated exposure to cocaine alters the modulation of mesocorticolimbic glutamate transmission by medial prefrontal cortex Group II metabotropic glutamate receptors. Journal of neurochemistry 20081001
Similar membrane affinity of mono- and Di-S-acylated ras membrane anchors: a new twist in the role of protein lipidation. Journal of the American Chemical Society 20080924
Selenocystine induces apoptosis of A375 human melanoma cells by activating ROS-mediated mitochondrial pathway and p53 phosphorylation. Cellular and molecular life sciences : CMLS 20080901
The undertow of sulfur metabolism on glutamatergic neurotransmission. Trends in biochemical sciences 20080901
Nanoparticulate glutathione peroxidase mimics based on selenocystine-pullulan conjugates. Bioconjugate chemistry 20080901
The photodimerization of a cinnamoyl moiety derivative in dilute solution based on the intramolecular chain interaction of gemini surfactant. The journal of physical chemistry. B 20080821
Blunted cystine-glutamate antiporter function in the nucleus accumbens promotes cocaine-induced drug seeking. Neuroscience 20080813
The xc- cystine/glutamate antiporter: a mediator of pancreatic cancer growth with a role in drug resistance. British journal of cancer 20080805
Cyst(e)ine imbalance and its effect on methionine precursor utilization in chicks. Journal of animal science 20080801
Acetazolamide is an effective adjunct for urinary alkalization in patients with uric acid and cystine stone formation recalcitrant to potassium citrate. Urology 20080801
Gene transfer may be preventive but not curative for a lysosomal transport disorder. Molecular therapy : the journal of the American Society of Gene Therapy 20080801
The characterization of selected drugs with infrared laser desorption/tunable synchrotron vacuum ultraviolet photoionization mass spectrometry. Rapid communications in mass spectrometry : RCM 20080801
Peptide cysteine thiyl radicals abstract hydrogen atoms from surrounding amino acids: the photolysis of a cystine containing model peptide. The journal of physical chemistry. B 20080731
Blockade of sensory abnormalities and kinin B(1) receptor expression by N-acetyl-L-cysteine and ramipril in a rat model of insulin resistance. European journal of pharmacology 20080728
A novel HPLC-UV/nano-TiO2-chemiluminescence system for the determination of selenocystine and selenomethionine. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080715
Identification of the major cysteine protease of Giardia and its role in encystation. The Journal of biological chemistry 20080627
The x(c)- cystine/glutamate antiporter: a potential target for therapy of cancer and other diseases. Journal of cellular physiology 20080601
Cysteamine prevents inhibition of thiol-containing enzymes caused by cystine or cystine dimethylester loading in rat brain cortex. Metabolic brain disease 20080601
Targeting cell death in vivo in experimental traumatic brain injury by a novel molecular probe. Journal of neurotrauma 20080601
Conserved structural determinants in three-fingered protein domains. The FEBS journal 20080601
[Cystine lithiasis: retrospective study about 25 cases]. La Tunisie medicale 20080601
Role of disulphide bonds in a thermophilic serine protease aqualysin I from Thermus aquaticus YT-1. Journal of biochemistry 20080501
Active control of surface properties and aggregation behavior in amino acid-based Gemini surfactant systems. Journal of colloid and interface science 20080501
Identification and subcellular localization of a new cystinosin isoform. American journal of physiology. Renal physiology 20080501
High-throughput determination of fudosteine in human plasma by liquid chromatography-tandem mass spectrometry, following protein precipitation in the 96-well plate format. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080501
The interactions between cysteamine, cystine and cumulus cells increase the intracellular glutathione level and developmental capacity of goat cumulus-denuded oocytes. Reproduction (Cambridge, England) 20080501
Enzymatic degradation of keratin films and keratin fibers prepared from human hair. Biological & pharmaceutical bulletin 20080501
Disulfide S-monoxides convert xanthine dehydrogenase into oxidase in rat liver cytosol more potently than their respective disulfides. Biological & pharmaceutical bulletin 20080501
Reactive sulfur species: kinetics and mechanism of the equilibrium between cysteine sulfenyl thiocyanate and cysteine thiosulfinate ester in acidic aqueous solution. The Journal of organic chemistry 20080418
Pulse radiolysis studies on reactions of hydroxyl radicals with selenocystine derivatives. The journal of physical chemistry. B 20080410
A role for glutamate in growth and invasion of primary brain tumors. Journal of neurochemistry 20080401
A cystine-cysteine shuttle mediated by xCT facilitates cellular responses to S-nitrosoalbumin. American journal of physiology. Cell physiology 20080401
The cystine/cysteine cycle: a redox cycle regulating susceptibility versus resistance to cell death. Oncogene 20080306
Cystinuria. Seminars in nephrology 20080301
Comparative digestibility of amino acids of maize, sorghum, finger millet and pearl millet in cockerels and Japanese quails. British poultry science 20080301
[Indirect determination of stability constant of zinc cystine chelate by flame atomic absorption spectrometry with ZnS]. Guang pu xue yu guang pu fen xi = Guang pu 20080301
Evaluation of cystine transport in cultured human kidney cells and establishment of cystinuria type I phenotype by antisense technology. Urological research 20080201
Individual response of growing pigs to sulphur amino acid intake. Journal of animal physiology and animal nutrition 20080201
Commentary: Sibling trials in Banbridge, County Down. International journal of epidemiology 20080201
Disulfide bond-dependent mechanism of protection against oxidative stress in pyruvate-ferredoxin oxidoreductase of anaerobic Desulfovibrio bacteria. Biochemistry 20080122
Bridging the gap between protein carboxyl methylation and phospholipid methylation to understand glucose-stimulated insulin secretion from the pancreatic beta cell. Biochemical pharmacology 20080115
Ultra-stable peptide scaffolds for protein engineering-synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2. Chembiochem : a European journal of chemical biology 20080104
The new oral immunomodulating drug DiNAC induces brachial artery vasodilatation at rest and during hyperemia in hypercholesterolemic subjects, likely by a nitric oxide-dependent mechanism. Atherosclerosis 20080101
Natural and artificial cystine knots for assembly of homo- and heterotrimeric collagen models. Antioxidants & redox signaling 20080101
Oxidative folding of cyclic cystine knot proteins. Antioxidants & redox signaling 20080101
A prominent role for mucosal cystine/cysteine metabolism in intestinal immunoregulation. Gastroenterology 20080101
Functional asymmetry of the conserved cystine loops in alphabetagamma GABA A receptors revealed by the response to GABA activation and drug potentiation. The international journal of biochemistry & cell biology 20080101
Iron regulates L-cystine uptake and glutathione levels in lens epithelial and retinal pigment epithelial cells by its effect on cytosolic aconitase. Investigative ophthalmology & visual science 20080101
Late-onset nephropathic cystinosis: clinical presentation, outcome, and genotyping. Clinical journal of the American Society of Nephrology : CJASN 20080101
Use of inhaled heparin/N-acetylcystine in inhalation injury: does it help? Journal of burn care & research : official publication of the American Burn Association 20080101
Synthesis and properties of N,N'-bis(5-aminosalicyl)-L-cystine as a colon-specific deliverer of 5-aminosalicylic acid and cystine. Drug delivery 20080101
Management of cystinuric patients: an observational, retrospective, single-centre analysis. Urologia internationalis 20080101
Hematological manifestations of nephropathic cystinosis. Acta haematologica 20080101
Effect of disulfide-containing compounds on the Na+ transport in the frog skin. Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20080101
Analysis on conservation of disulphide bonds and their structural features in homologous protein domain families. BMC structural biology 20080101
Differential regulation of cell proliferation in neurogenic zones in mice lacking cystine transport by xCT. Biochemical and biophysical research communications 20071221
beta-sheet hydrogen bonding patterns in cystine peptides. Organic letters 20071220
Chemical disulfide mapping identifies an inhibitor cystine knot in the agouti signaling protein. FEBS letters 20071211
Suppression by glutamate of proliferative activity through glutathione depletion mediated by the cystine/glutamate antiporter in mesenchymal C3H10T1/2 stem cells. Journal of cellular physiology 20071201
A review of the role of enhanced apoptosis in the pathophysiology of cystinosis. Molecular genetics and metabolism 20071201
Cystine calculi: correlation of CT-visible structure, CT number, and stone morphology with fragmentation by shock wave lithotripsy. Urological research 20071201
Noninvasive differentiation of uric acid versus non-uric acid kidney stones using dual-energy CT. Academic radiology 20071201
Enhancement of antigen-specific immunoglobulin G production in mice by co-administration of L-cystine and L-theanine. The Journal of veterinary medical science 20071201
Role of the asymmetry of the homodimeric b2 stator stalk in the interaction with the F1 sector of Escherichia coli ATP synthase. The Journal of biological chemistry 20071102
Protein-thiol substitution or protein dethiolation by thiol/disulfide exchange reactions: the albumin model. Proteins 20071101
Cystinuria in children and young adults: success of monitoring free-cystine urine levels. Pediatric nephrology (Berlin, Germany) 20071101
Mechanisms of root canal sealers cytotoxicity on osteoblastic cell line MC3T3-E1. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20071101
Raman spectroscopy and DFT calculations of As(III) complexation with a cysteine-rich biomaterial. Journal of colloid and interface science 20071101
Comparison of collision-induced dissociation and electron-induced dissociation of singly protonated aromatic amino acids, cystine and related simple peptides using a hybrid linear ion trap-FT-ICR mass spectrometer. Analytical and bioanalytical chemistry 20071101
DL-Methionine is as efficacious as L-methionine, but modest L-cystine excesses are anorexigenic in sulfur amino acid-deficient purified and practical-type diets fed to chicks. Poultry science 20071101
Mapping of glutathione and its precursor amino acids reveals a role for GLYT2 in glycine uptake in the lens core. Investigative ophthalmology & visual science 20071101
[Massive residual stones after ESWL for staghorn cystine calculi were completely dissolved by oral administration of alkaline citrate: a case report]. Hinyokika kiyo. Acta urologica Japonica 20071101
A-366833: a novel nicotinonitrile-substituted 3,6-diazabicyclo[3.2.0]-heptane alpha4beta2 nicotinic acetylcholine receptor selective agonist: Synthesis, analgesic efficacy and tolerability profile in animal models. Biochemical pharmacology 20071015
Extracellular cysteine/cystine redox potential controls lung fibroblast proliferation and matrix expression through upregulation of transforming growth factor-beta. American journal of physiology. Lung cellular and molecular physiology 20071001
'Forbidden' disulfides: their role as redox switches. Current protein & peptide science 20071001
Intrinsic fluorescence reports a global conformational change in the N-lobe of human serum transferrin following iron release. Biochemistry 20070918
Control of extracellular cysteine/cystine redox state by HT-29 cells is independent of cellular glutathione. American journal of physiology. Regulatory, integrative and comparative physiology 20070901
Elution behavior of diaminopimelic acid and related diamino acids using the advanced Marfey's method. Journal of chromatography. A 20070810
Biogenesis of the essential Tim9-Tim10 chaperone complex of mitochondria: site-specific recognition of cysteine residues by the intermembrane space receptor Mia40. The Journal of biological chemistry 20070803
Promotion of oxidative stress in kidney of rats loaded with cystine dimethyl ester. Pediatric nephrology (Berlin, Germany) 20070801
Improved sequencing of oxidized cysteine and methionine containing peptides using electron transfer dissociation. Journal of the American Society for Mass Spectrometry 20070801
Cystine dimethylester model of cystinosis: still reliable? Pediatric research 20070801
Clinical presentation of CADASIL in an Italian patient with a rare Gly528Cys exon 10 NOTCH3 gene mutation. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20070801
Organelle redox of CF and CFTR-corrected airway epithelia. Free radical biology & medicine 20070715
Paracetamol overdose as a result of dental pain requiring medical treatment - two case reports. British dental journal 20070714
Effect of cysteine and cystine addition on sensory profile and potent odorants of extruded potato snacks. Journal of agricultural and food chemistry 20070711
The disulfide bond pattern of salmon egg lectin 24K from the Chinook salmon Oncorhynchus tshawytscha. Archives of biochemistry and biophysics 20070701
Haemophagocytosis by myeloid precursors in lysinuric protein intolerance. British journal of haematology 20070701
In vitro toxicity induced by methylmercury on sympathetic neurons is reverted by L-cysteine or glutathione. Neuroscience research 20070701
Modification of Gd-DTPA cystine copolymers with PEG-1000 optimizes pharmacokinetics and tissue retention for magnetic resonance angiography. Magnetic resonance in medicine 20070701
1H, 13C and 15N resonance assignment of the oxidized form (Cys(67)-Cys (70)) of the N-terminal domain of PilB from Neisseria meningitidis. Biomolecular NMR assignments 20070701
A mass spectrometric investigation of native and oxidatively inactivated chloroperoxidase. Chembiochem : a European journal of chemical biology 20070618
Protect from light: photodegradation and protein biologics. Journal of pharmaceutical sciences 20070601
Upregulation of cerebral cortical glutathione synthesis by ammonia in vivo and in cultured glial cells: the role of cystine uptake. Neurochemistry international 20070601
Chemoprevention of smoke-induced alopecia in mice by oral administration of L-cystine and vitamin B6. Journal of dermatological science 20070601
Expression and developmental regulation of the cystine/glutamate exchanger (xc-) in the rat. Neurochemical research 20070601
Measurement of cystine in granulocytes using liquid chromatography-tandem mass spectrometry. Clinical biochemistry 20070601
Crim1KST264/KST264 mice implicate Crim1 in the regulation of vascular endothelial growth factor-A activity during glomerular vascular development. Journal of the American Society of Nephrology : JASN 20070601
Monitoring of chemotherapy-induced cell death in melanoma tumors by N,N'-Didansyl-L-cystine. Technology in cancer research & treatment 20070601
Isolated cystinuria (OMIM 238200) is not a separate entity but is caused by a mutation in the cystinuria gene SLC7A9. Clinical genetics 20070601
Amino acid composition of two masticatory nuts (Cola acuminata and Garcinia kola) and a snack nut (Anacardium occidentale). International journal of food sciences and nutrition 20070601
System xc- and glutamate transporter inhibition mediates microglial toxicity to oligodendrocytes. Journal of immunology (Baltimore, Md. : 1950) 20070515
Cystine-modified biomass for Cd(II) and Pb(II) biosorption. Journal of hazardous materials 20070508
Novel molecular imaging of cell death in experimental cerebral stroke. Brain research 20070504
Ceftriaxone associated nephrolithiasis: a prospective study in 284 children. Pediatric nephrology (Berlin, Germany) 20070501
Glycosides from the stem bark of Fraxinus sieboldiana. Journal of natural products 20070501
Protective effect of a novel cystine C(60) derivative on hydrogen peroxide-induced apoptosis in rat pheochromocytoma PC12 cells. Chemico-biological interactions 20070425
Modulation of cellular disulfide-bond formation and the ER redox environment by feedback regulation of Ero1. Cell 20070420
Expression and function of cystine/glutamate transporter in neutrophils. Journal of leukocyte biology 20070401
Glutamate suppresses osteoclastogenesis through the cystine/glutamate antiporter. The American journal of pathology 20070401
A Ser326Cys polymorphism in the DNA repair gene hOGG1 is not associated with sporadic Alzheimer's disease. Neuroscience letters 20070313
Evaluation and improvement of the properties of the novel cystine-knot microprotein McoEeTI for oral administration. International journal of pharmaceutics 20070306
Linkage between the intramembrane H-bond network around aspartic acid 83 and the cytosolic environment of helix 8 in photoactivated rhodopsin. Journal of molecular biology 20070302
The Uromodulin C744G mutation causes MCKD2 and FJHN in children and adults and may be due to a possible founder effect. Kidney international 20070301
N-acetylcysteine reduces lipopolysaccharide-sensitized hypoxic-ischemic brain injury. Annals of neurology 20070301
Regional differences in cystine accumulation point to a sutural delivery pathway to the lens core. Investigative ophthalmology & visual science 20070301
[Modulation of the phenotypic expression in the patient with cystinuria: influence of therapeutic intervention and diet]. Archivos espanoles de urologia 20070301
The lathyrus toxin, beta-N-oxalyl-L-alpha,beta-diaminopropionic acid (ODAP), and homocysteic acid sensitize CA1 pyramidal neurons to cystine and L-2-amino-6-phosphonohexanoic acid. Toxicology and applied pharmacology 20070215
Identification of an intersubunit cross-link between substituted cysteine residues located in the putative ATP binding site of the P2X1 receptor. The Journal of neuroscience : the official journal of the Society for Neuroscience 20070207
Sulfasalazine-induced cystine starvation: potential use for prostate cancer therapy. The Prostate 20070201
Ligands selective for alpha4beta2 but not alpha3beta4 or alpha7 nicotinic receptors generalise to the nicotine discriminative stimulus in the rat. Psychopharmacology 20070201
Effects of long-term zinc supplementation on plasma thiol metabolites and redox status in patients with age-related macular degeneration. American journal of ophthalmology 20070201
High-throughput synthesis of conopeptides: a safety-catch linker approach enabling disulfide formation in 96-well format. Journal of peptide science : an official publication of the European Peptide Society 20070201
Cystine inhibits creatine kinase activity in pig retina. Archives of medical research 20070201
A characteristic phenotypic retinal appearance in Norrie disease. Retina (Philadelphia, Pa.) 20070201
The CARI guidelines. Kidney stones: cystine stones. Nephrology (Carlton, Vic.) 20070201
Human eosinophil major basic protein 2: location of disulfide bonds and free sulfhydryl groups. The protein journal 20070101
N,N-diacetyl-L-cystine improves endothelial function in atherosclerotic Watanabe heritable hyperlipidaemic rabbits. Basic & clinical pharmacology & toxicology 20070101
Nephropathic cystinosis with bone marrow involvement. British journal of haematology 20070101
A novel multielemental scanning thermal analysis (MESTA) method for the identification and characterization of solid substances. Journal of AOAC International 20070101
Modification of proteins by cyclopentenone prostaglandins is differentially modulated by GSH in vitro. Annals of the New York Academy of Sciences 20070101
Kinetics of uptake and deacetylation of N-acetylcysteine by human erythrocytes. The international journal of biochemistry & cell biology 20070101
Effect of saliva, epigallocatechin gallate and hypoxia on Cu-induced oxidation and cytotoxicity. In vivo (Athens, Greece) 20070101
Pathophysiology and clinical aspects of urinary lithiasis. Urologia internationalis 20070101
Prevention of stone disease. Urologia internationalis 20070101
Fundamental DSC investigations of alpha-keratinous materials as basis for the interpretation of specific effects of chemical, cosmetic treatments on human hair. Journal of cosmetic science 20070101
Composition and clinically determined hardness of urinary tract stones. Scandinavian journal of urology and nephrology 20070101
Excess dietary cystine intensifies the adverse effect of a methionine deficiency in the cat. Journal of animal physiology and animal nutrition 20061201
CART (85-102)-inhibition of psychostimulant-induced hyperlocomotion: importance of cyclization. Peptides 20061201
Cystine calculi: challenging group of stones. Postgraduate medical journal 20061201
Inhibition of plasminogen activator inhibitor-1 binding to endocytosis receptors of the low-density-lipoprotein receptor family by a peptide isolated from a phage display library. The Biochemical journal 20061101
Ion-exchange and potentiometric characterization of Al-cystine and Al-cysteine complexes. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20061101
Cyclic insulin-regulated aminopeptidase (IRAP)/AT4 receptor ligands. Journal of peptide science : an official publication of the European Peptide Society 20061101
[Modern general metaphylaxis of stone disease. New risks, new evidence, new recommendations]. Der Urologe. Ausg. A 20061101
Preclinical antitumor activity, pharmacokinetics and pharmacodynamics of imexon in mice. Anti-cancer drugs 20061101
Simultaneous quantitation of homocysteine, cysteine and methionine in plasma and urine by liquid chromatography-tandem mass spectrometry. Annals of clinical biochemistry 20061101
Cysteine, cystine or N-acetylcysteine supplementation in parenterally fed neonates. The Cochrane database of systematic reviews 20061018
Kinetics and mechanisms of chlorine dioxide and chlorite oxidations of cysteine and glutathione. Inorganic chemistry 20061016
Cystine/glutamate exchange modulates glutathione supply for neuroprotection from oxidative stress and cell proliferation. The Journal of neuroscience : the official journal of the Society for Neuroscience 20061011
Multi-template approach to modeling engineered disulfide bonds. Proteins 20061001
Controlled synthesis of (S,S)-2,7-diaminosuberic acid: a method for regioselective construction of dicarba analogues of multicystine-containing peptides. The Journal of organic chemistry 20060929
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Glutamate inhibits chondral mineralization through apoptotic cell death mediated by retrograde operation of the cystine/glutamate antiporter. The Journal of biological chemistry 20060825
LDL oxidized with iron in the presence of homocysteine/cystine at acidic pH has low cytotoxicity despite high lipid peroxidation. Atherosclerosis 20060801
Protective role of L-2-oxothiazolidine-4-carboxylic acid in cisplatin-induced renal injury. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060801
Pharmacokinetics, biodistribution and contrast enhanced MR blood pool imaging of Gd-DTPA cystine copolymers and Gd-DTPA cystine diethyl ester copolymers in a rat model. Pharmaceutical research 20060801
Cysteamine dose regimen. Pediatric nephrology (Berlin, Germany) 20060801
New separation method for organic and inorganic selenium compounds based on anion exchange chromatography followed by inductively coupled plasma mass spectrometry. Analytical and bioanalytical chemistry 20060801
Inhibition of creatine kinase activity by cystine in the kidney of young rats. Pediatric research 20060801
Adaptational modification and ligand occupancy have opposite effects on positioning of the transmembrane signalling helix of a chemoreceptor. Molecular microbiology 20060801
Disulfide bridge disruption in the alpha2 domain of the HLA class I molecule leads to low expression of the corresponding antigen. Human immunology 20060801
Effects of selenocystine on lead-exposed Chinese hamster ovary (CHO) and PC-12 cells. Toxicology and applied pharmacology 20060715
Cystine alters the renal and hepatic disposition of inorganic mercury and plasma thiol status. Toxicology and applied pharmacology 20060701
A new class of [2Fe-2S]-cluster-containing protoporphyrin (IX) ferrochelatases. The Biochemical journal 20060701
Ser351Cys mutation in the fibroblast growth factor receptor 2 gene results in severe Pfeiffer syndrome. Clinical dysmorphology 20060701
Irreversible thermal denaturation of elongation factor Ts from Thermus thermophilus effect of the residual structure and intermonomer disulfide bond. Biochimica et biophysica acta 20060701
nDsbD: a redox interaction hub in the Escherichia coli periplasm. Cellular and molecular life sciences : CMLS 20060701
Blockade of the translocation and activation of mitogen-activated protein kinase kinase 4 (MKK4) signaling attenuates neuronal damage during later ischemia-reperfusion. Journal of neurochemistry 20060701
Conformational stability of secretory leucocyte protease inhibitor: a protein with no hydrophobic core and very little secondary structure. Biochimica et biophysica acta 20060701
Direct amino acid analysis method for speciation of selenoamino acids using high-performance anion-exchange chromatography coupled with integrated pulsed amperometric detection. Journal of chromatography. A 20060616
Selenium speciation by high-performance anion-exchange chromatography-post-column UV irradiation coupled with atomic fluorescence spectrometry. Journal of chromatography. A 20060616
Rapid synthesis of a register-specific heterotrimeric type I collagen helix encompassing the integrin alpha2beta1 binding site. Journal of molecular biology 20060602
Reduced renal function and benefits of treatment in cystinuria vs other forms of nephrolithiasis. BJU international 20060601
Renal crystal deposits and histopathology in patients with cystine stones. Kidney international 20060601
Gd-DTPA L-cystine bisamide copolymers as novel biodegradable macromolecular contrast agents for MR blood pool imaging. Pharmaceutical research 20060601
Understanding intestinal cysteamine bitartrate absorption. The Journal of pediatrics 20060601
Non-covalent binding of fullerenes and biomolecules at surface-supported metallosupramolecular receptors. Chemical communications (Cambridge, England) 20060528
Norcystine, a new tool for the study of the structure-activity relationship of peptides. Organic letters 20060525
Role of the Cys18-Cys274 disulfide bond and of the third extracellular loop in the constitutive activation and internalization of angiotensin II type 1 receptor. Regulatory peptides 20060515
Quantification of fudosteine in human plasma by high-performance liquid chromatography-electrospray ionization mass spectrometry employing precolumn derivatization with 9-fluorenylmethyl chloroformate. Journal of mass spectrometry : JMS 20060501
The electrochemical reaction mechanism of selenocystine on selenium-gold film modified glassy carbon electrode. Colloids and surfaces. B, Biointerfaces 20060501
Design and synthesis of potent cystine-free cyclic hexapeptide agonists at the human urotensin receptor. Organic letters 20060427
Hydrophobin HFBII in detail: ultrahigh-resolution structure at 0.75 A. Acta crystallographica. Section D, Biological crystallography 20060401
The potential of cystine-knot microproteins as novel pharmacophoric scaffolds in oral peptide drug delivery. Journal of drug targeting 20060401
Examination of the slow unfolding of pro-nerve growth factor argues against a loop threading mechanism for nerve growth factor. Biochemistry 20060321
Consequences of ERp57 deletion on oxidative folding of obligate and facultative clients of the calnexin cycle. The Journal of biological chemistry 20060310
ApoSense: a novel technology for functional molecular imaging of cell death in models of acute renal tubular necrosis. European journal of nuclear medicine and molecular imaging 20060301
New oxo-bridged peroxotungsten complexes containing biogenic co-ligand as potent inhibitors of alkaline phosphatase activity. Molecular and cellular biochemistry 20060301
A proteomic approach to verify in vivo expression of a novel gamma-gliadin containing an extra cysteine residue. Proteomics 20060301
Urinary cystine excretion and capacity in patients with cystinuria. Kidney international 20060301
Effects of supplemental cystine or methionine on growth and lifespan of stroke-prone spontaneously hypertensive rats. The British journal of nutrition 20060301
The cyclotides and related macrocyclic peptides as scaffolds in drug design. Current opinion in drug discovery & development 20060301
S-nitrosocysteine elicits hemodynamic responses similar to those of the Bezold-Jarisch reflex via activation of stereoselective recognition sites. European journal of pharmacology 20060215
Ascorbic acid reduction of microtubule protein disulfides and its relevance to protein S-nitrosylation assays. Biochemical and biophysical research communications 20060210
Effect of pH on one-electron oxidation chemistry of organoselenium compounds in aqueous solutions. The journal of physical chemistry. A 20060209
Adeno-associated virus-mediated gene transfer of a secreted form of TRAIL inhibits tumor growth and occurrence in an experimental tumor model. The journal of gene medicine 20060201
Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif. The Biochemical journal 20060201
Effect of amino acids containing sulfur on dithiolopyrrolone antibiotic productions by Saccharothrix algeriensis NRRL B-24137. Journal of applied microbiology 20060201
High plasma cyst(e)ine level may indicate poor clinical outcome in patients with acute stroke: possible involvement of hydrogen sulfide. Journal of neuropathology and experimental neurology 20060201
Biosynthesis of the cyclotide Kalata B1 by using protein splicing. Angewandte Chemie (International ed. in English) 20060130
The central role of metal coordination in selenium antioxidant activity. Inorganic chemistry 20060123
Enrichment of in vitro maturation medium for buffalo (Bubalus bubalis) oocytes with thiol compounds: effects of cystine on glutathione synthesis and embryo development. Theriogenology 20060120
Protein kinase B/Akt is a novel cysteine string protein kinase that regulates exocytosis release kinetics and quantal size. The Journal of biological chemistry 20060120
Scanning cysteine mutagenesis analysis of Abeta-(1-40) amyloid fibrils. The Journal of biological chemistry 20060113
Strict cysteamine dose regimen is required to prevent nocturnal cystine accumulation in cystinosis. Pediatric nephrology (Berlin, Germany) 20060101
On the kinetics and mechanism of the reaction of cysteine and hydrogen peroxide in aqueous solution. Journal of pharmaceutical sciences 20060101
Application of an exact mathematical model and the steady-state approximation to the kinetics of the reaction of cysteine and hydrogen peroxide in aqueous solution: a reply to the Ashby and Nagy commentary. Journal of pharmaceutical sciences 20060101
Heterogeneous mutations in the SLC3A1 and SLC7A9 genes in Chinese patients with cystinuria. Kidney international 20060101
Oleandrin-mediated oxidative stress in human melanoma cells. Journal of experimental therapeutics & oncology 20060101
A robust hybrid peptide crystal formed with weak hydrogen bonds. Biopolymers 20060101
The effect of engineered disulfide bonds on the stability of Drosophila melanogaster acetylcholinesterase. BMC biochemistry 20060101
Xenobiotics in vitro: the influence of L-cystine, pantothenat, and miliacin on metabolic and proliferative capacity of keratinocytes. Cutaneous and ocular toxicology 20060101
Ebselen attenuates oxidative stress in ischemic astrocytes depleted of glutathione. Comparison with glutathione precursors. Pharmacological reports : PR 20060101
The pharmacokinetics of orally administered fudosteine in healthy Chinese volunteers. European journal of drug metabolism and pharmacokinetics 20060101
[Cystinosis--an orphan disease. Pathogenesis and current treatment]. Przeglad lekarski 20060101
Renal lithiasis and nutrition. Nutrition journal 20060101
Redefining oxidative stress. Antioxidants & redox signaling 20060101
[Nuclear organization and expression of milk protein genes]. Journal de la Societe de biologie 20060101
Cytisine for the treatment of nicotine addiction: from a molecule to therapeutic efficacy. Pharmacological reports : PR 20060101
Characterization of the redox and metal binding activity of BsSco, a protein implicated in the assembly of cytochrome c oxidase. Biochemistry 20051227
A unified view of the role of electrostatic interactions in modulating the gating of Cys loop receptors. The Journal of biological chemistry 20051216
A novel conotoxin framework with a helix-loop-helix (Cs alpha/alpha) fold. Biochemistry 20051213
The two cysteine-rich head domains of minicollagen from Hydra nematocysts differ in their cystine framework and overall fold despite an identical cysteine sequence pattern. Journal of molecular biology 20051202
Biochemical characterization, stability studies and N-terminal sequence of a bi-functional inhibitor from Phaseolus aureus Roxb. (Mung bean). Biochimie 20051201
Expression in Escherichia coli and disulfide bridge mapping of PSC33, an allergenic 2S albumin from peanut. Protein expression and purification 20051201
Sulfur amino acids in Cushing's disease: insight in homocysteine and taurine levels in patients with active and cured disease. The Journal of clinical endocrinology and metabolism 20051201
Distinct nuclear factor-kappaB/Rel proteins have opposing modulatory effects in glutamate-induced cell death in HT22 cells. Neurochemistry international 20051201
Urine sediment from a Chihuahua. Veterinary clinical pathology 20051201
Urological intervention in patients with cystinuria is decreased with medical compliance. The Journal of urology 20051201
Crystal structure of a non-hemorrhagic fibrin(ogen)olytic metalloproteinase complexed with a novel natural tri-peptide inhibitor from venom of Agkistrodon acutus. Journal of structural biology 20051201
Antioxidant supplements prevent oxidation of cysteine/cystine redox in patients with age-related macular degeneration. American journal of ophthalmology 20051201
Relationship between zinc parameters and either body weight gain, protein intake or survival time in zinc-deficient rats. Journal of nutritional science and vitaminology 20051201
Persistent glycoprotein misfolding activates the glucosidase II/UGT1-driven calnexin cycle to delay aggregation and loss of folding competence. Molecular cell 20051123
Elevated oxidized glutathione in cystinotic proximal tubular epithelial cells. Biochemical and biophysical research communications 20051118
Study of primary amines for nucleophilic cleavage of cyanylated cystinyl proteins in disulfide mass mapping methodology. Analytical biochemistry 20051115
Redox imbalance in cystine/glutamate transporter-deficient mice. The Journal of biological chemistry 20051111
Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5). Carcinogenesis 20051101
Fatigue of kidney stones with heterogeneous microstructure subjected to shock-wave lithotripsy. Journal of biomedical materials research. Part B, Applied biomaterials 20051101
Nephrolithiasis in children. Pediatric nephrology (Berlin, Germany) 20051101
Prenatal diagnosis of cystinosis by quantitative measurement of cystine in chorionic villi and cultured cells. Prenatal diagnosis 20051101
Confocal microscopy of the cornea in nephropathic cystinosis. The British journal of ophthalmology 20051101
The role of the disulfide bond in amyloid-like fibrillogenesis in a model peptide system. Organic & biomolecular chemistry 20051007
The effects of the interactions between amino acids on pyruvate kinase activity from the brain cortex of young rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20051001
Protective effect of L-trans-pyrrolidine-2,4-dicarboxilic acid preload against cell death induced by oxygen/glucose deprivation in differentiated PC12 cells. Journal of neuroscience research 20051001
Setaria cervi: kinetic studies of filarial glutathione synthetase by high performance liquid chromatography. Experimental parasitology 20051001
Iron accelerates the conversion of dopamine-oxidized intermediates into melanin and provides protection in SH-SY5Y cells. Journal of neuroscience research 20051001
Ascorbate is particularly effective against LDL oxidation in the presence of iron(III) and homocysteine/cystine at acidic pH. Biochimica et biophysica acta 20051001
[Pharmacokinetics of fudosteine in healthy volunteers]. Yao xue xue bao = Acta pharmaceutica Sinica 20051001
Chiral recognition of dextran sulfate with D- and L-cystine studied by multiwavelength surface plasmon resonance. Carbohydrate research 20050905
Altered status of glutathione and its metabolites in cystinotic cells. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050901
Carboxy-terminal truncations modify the outer pore vestibule of muscle chloride channels. Biophysical journal 20050901
The effect of pressure on the crystal structure of hexagonal L-cystine. Journal of synchrotron radiation 20050901
High cystine in platelets from patients with nephropathic cystinosis: a chemical, ultrastructural, and functional evaluation. Journal of clinical pathology 20050901
Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance. Cancer research 20050815
Inhibition of cystine uptake disrupts the growth of primary brain tumors. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050803
Cystine and glutamate transport in renal epithelial cells transfected with human system x(-) (c). Kidney international 20050801
Mapping the functional domains of human transcobalamin using monoclonal antibodies. The FEBS journal 20050801
Effects of cystine and hydrogen peroxide on glutathione status and expression of antioxidant genes in Escherichia coli. Biochemistry. Biokhimiia 20050801
Disulfide exchange in hydrogen-bonded cyclic assemblies: stereochemical self-selection by double dynamic chemistry. The Journal of organic chemistry 20050722
Progressive degeneration of human mesencephalic neuron-derived cells triggered by dopamine-dependent oxidative stress is dependent on the mixed-lineage kinase pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050706
Cystine/glutamate exchange regulates metabotropic glutamate receptor presynaptic inhibition of excitatory transmission and vulnerability to cocaine seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050706
Extracellular cysteine/cystine redox regulates the p44/p42 MAPK pathway by metalloproteinase-dependent epidermal growth factor receptor signaling. American journal of physiology. Gastrointestinal and liver physiology 20050701
Intravenous N-acetylcysteine does not prevent post-ERCP pancreatitis. Gastrointestinal endoscopy 20050701
Crystal structure of a secreted insect ferritin reveals a symmetrical arrangement of heavy and light chains. Journal of molecular biology 20050610
Intracellular proatherogenic events and cell adhesion modulated by extracellular thiol/disulfide redox state. Circulation 20050607
O-raffinose crosslinked hemoglobin lacks site-specific chemistry in the central cavity: structural and functional consequences of beta93Cys modification. Proteins 20050601
Transport of L-[14C]cystine and L-[14C]cysteine by subtypes of high affinity glutamate transporters over-expressed in HEK cells. Neurochemistry international 20050601
Reactive sulfur species: kinetics and mechanism of the oxidation of cystine by hypochlorous acid to give N,N'-dichlorocystine. Chemical research in toxicology 20050601
New binding specificities derived from Min-23, a small cystine-stabilized peptidic scaffold. Biochemistry 20050517
Catalytic and direct oxidation of cysteine by octacyanomolybdate(V). Inorganic chemistry 20050516
Conformationally sensitive residues in extracellular loop 5 of the Na+/dicarboxylate co-transporter. The Journal of biological chemistry 20050513
Aortic dissection and ankylosing spondylitis in hypocystinemia. The Journal of thoracic and cardiovascular surgery 20050501
ERS1 encodes a functional homologue of the human lysosomal cystine transporter. The FEBS journal 20050501
Misfolding of collagen X chains harboring Schmid metaphyseal chondrodysplasia mutations results in aberrant disulfide bond formation, intracellular retention, and activation of the unfolded protein response. The Journal of biological chemistry 20050422
Chronic nicotine and dizocilpine effects on regionally specific nicotinic and NMDA glutamate receptor binding. Brain research 20050418
Radiolytic modification of sulfur-containing amino acid residues in model peptides: fundamental studies for protein footprinting. Analytical chemistry 20050415
Cysteamine prevents and reverses the inhibition of creatine kinase activity caused by cystine in rat brain cortex. Neurochemistry international 20050401
Measurement of cystine in urine by liquid chromatography-tandem mass spectrometry. Clinical chemistry 20050401
Oxidative folding of conotoxins sharing an identical disulfide bridging framework. The FEBS journal 20050401
Apparent fragility of African hair is unrelated to the cystine-rich protein distribution: a cytochemical electron microscopic study. Experimental dermatology 20050401
Lactococcus lactis uses MscL as its principal mechanosensitive channel. The Journal of biological chemistry 20050311
Oxidant-induced apoptosis in human retinal pigment epithelial cells: dependence on extracellular redox state. Investigative ophthalmology & visual science 20050301
Molecular electron transfer of protein junctions characterised by conducting atomic force microscopy. Colloids and surfaces. B, Biointerfaces 20050225
A pulsed potential waveform displaying enhanced detection capabilities towards sulfur-containing compounds at a gold working electrode. Journal of chromatography. A 20050225
Lysosomal cystine augments apoptosis and causes the phenotype in cystinosis. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20050218
Peroxynitrite-mediated oxidation of the C85S/C152E mutant of dihydrofolate reductase from Escherichia coli: functional and structural effects. Archives of biochemistry and biophysics 20050215
Evidence that the fosfomycin target Cys115 in UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) is essential for product release. The Journal of biological chemistry 20050204
Effect of the chemical form of supranutritional selenium on selenium load and selenoprotein activities in virgin, pregnant, and lactating rats. Journal of animal science 20050201
Transient neonatal cystinuria. Kidney international 20050201
Characterization of tiger-tail banding and hair shaft abnormalities in trichothiodystrophy. Journal of the American Academy of Dermatology 20050201
[Cystinosis: an infrequent cause of distal myopathy]. Revista de neurologia 20050201
Mammalian isovalthine metabolism. Journal of animal physiology and animal nutrition 20050201
Thimerosal neurotoxicity is associated with glutathione depletion: protection with glutathione precursors. Neurotoxicology 20050101
A fusion protein system for the recombinant production of short disulfide bond rich cystine knot peptides using barnase as a purification handle. Protein expression and purification 20050101
Synthesis of single- and multiple-stranded cystine-rich peptides. Biopolymers 20050101
Inhibition of endotoxin- and antigen-induced airway inflammation by fudosteine, a mucoactive agent. Pulmonary pharmacology & therapeutics 20050101
Ureteroscopy for pediatric urolithiasis: an evolving first-line therapy. Urology 20050101
BspA (CyuC) in Lactobacillus fermentum BR11 is a highly expressed high-affinity L-cystine-binding protein. Current microbiology 20050101
PEG-g-poly(GdDTPA-co-L-cystine): effect of PEG chain length on in vivo contrast enhancement in MRI. Biomacromolecules 20050101
cDNA cloning and functional expression of a Ca2+-sensing receptor with truncated C-terminal tail from the Mozambique tilapia (Oreochromis mossambicus). The Journal of biological chemistry 20041217
Transcriptional control of cystine/glutamate transporter gene by amino acid deprivation. Biochemical and biophysical research communications 20041203
Cys-His proteases are among the wired proteins of the cell. Archives of biochemistry and biophysics 20041201
Selective liberation of NO from S-nitrosocysteine with potassium thiocyanate, as monitored by an amperometric sensor. Archives of biochemistry and biophysics 20041201
[Study on the interaction of cystine and polyphenol oxidase from nicotian tobaccum]. Guang pu xue yu guang pu fen xi = Guang pu 20041201
Transmembrane segment 3 of the Glut1 glucose transporter is an outer helix. The Journal of biological chemistry 20041105
Glutathione precursors replenish decreased glutathione pool in cystinotic cell lines. Biochemical and biophysical research communications 20041105
Helical CT evaluation of the chemical composition of urinary tract calculi with a discriminant analysis of CT-attenuation values and density. European radiology 20041101
Mode of presentation and first line of management of non-recurrent urolithiasis in Kuwait. International journal of urology : official journal of the Japanese Urological Association 20041101
Solution structure of Cu6 metallothionein from the fungus Neurospora crassa. European journal of biochemistry 20041101
Shewanella profunda sp. nov., isolated from deep marine sediment of the Nankai Trough. International journal of systematic and evolutionary microbiology 20041101
Exploiting thiol modifications. PLoS biology 20041101
Disulfide bonds, their stereospecific environment and conservation in protein structures. Protein engineering, design & selection : PEDS 20041101
In vivo homodimerisation of HTLV-1 Gag and MA gives clues to the retroviral capsid and TM envelope protein arrangement. Journal of molecular biology 20041029
Structure of a human A-type potassium channel interacting protein DPPX, a member of the dipeptidyl aminopeptidase family. Journal of molecular biology 20041029
C-S bond formation reaction between a phenolate and disulfide-bridged dicopper(I) complexes. Inorganic chemistry 20041018
The Lathyrus excitotoxin beta-N-oxalyl-L-alpha,beta-diaminopropionic acid is a substrate of the L-cystine/L-glutamate exchanger system xc-. Toxicology and applied pharmacology 20041015
Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding. The Journal of biological chemistry 20041008
Trans-editing of Cys-tRNAPro by Haemophilus influenzae YbaK protein. The Journal of biological chemistry 20041008
Perioperative care of the patient with nephropathic cystinosis. Paediatric anaesthesia 20041001
Treatment of cystinosis: simple in principle, difficult in practice. The Journal of pediatrics 20041001
Long-term follow-up of well-treated nephropathic cystinosis patients. The Journal of pediatrics 20041001
Interrelationship between methionine and cystine of early Peking ducklings. Poultry science 20041001
Influence of N,N'-diacetyl-L-cystine on D-galactosamine/lipopolysaccharide induced immunological liver failure in mice. Yao xue xue bao = Acta pharmaceutica Sinica 20041001
Excitatory amino acid induced oligodendrocyte cell death in vitro: receptor-dependent and -independent mechanisms. Journal of neurochemistry 20040901
Comparison of cystine determination in mixed leukocytes vs polymorphonuclear leukocytes for diagnosis of cystinosis and monitoring of cysteamine therapy. Clinical chemistry 20040901
NCD3G: a novel nine-cysteine domain in family 3 GPCRs. Trends in biochemical sciences 20040901
An unconventional hypothesis of oxidation in Alzheimer's disease: intersections with excitotoxicity. Frontiers in bioscience : a journal and virtual library 20040901
Cysteine/cystine couple is a newly recognized node in the circuitry for biologic redox signaling and control. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040801
Spiral computed tomography: role in determination of chemical compositions of pure and mixed urinary stones--an in vitro study. Urology 20040801
The structure of the Cys-rich terminal domain of Hydra minicollagen, which is involved in disulfide networks of the nematocyst wall. The Journal of biological chemistry 20040716
Two conserved cysteine triads in human Ero1alpha cooperate for efficient disulfide bond formation in the endoplasmic reticulum. The Journal of biological chemistry 20040716
Isolation and characterization at cholinergic nicotinic receptors of a neurotoxin from the venom of the Acanthophis sp. Seram death adder. Biochemical pharmacology 20040715
Membrane binding modulates the quaternary structure of CTP:phosphocholine cytidylyltransferase. The Journal of biological chemistry 20040702
Molecular pathogenesis of cystinosis: effect of CTNS mutations on the transport activity and subcellular localization of cystinosin. Human molecular genetics 20040701
Hydrogen sulfide protects neurons from oxidative stress. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040701
Study of selenium distribution in the protein fractions of the Brazil nut, Bertholletia excelsa. Journal of agricultural and food chemistry 20040630
Cysteamine prevents and reverses the inhibition of pyruvate kinase activity caused by cystine in rat heart. Biochimica et biophysica acta 20040628
Inhibition of pyruvate kinase activity by cystine in brain cortex of rats. Brain research 20040625
Glial glutamate transporters limit spillover activation of presynaptic NMDA receptors and influence synaptic inhibition of Purkinje neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 20040623
[Cystinosis: diagnosis through the measurement of the leukocyte cystine content by HPLC]. Medicina clinica 20040619
Entrapment and release of quinoline derivatives using a hydrogel of a low molecular weight gelator. Journal of controlled release : official journal of the Controlled Release Society 20040618
[Cystinosis: deposition of cystine crystals in the bone marrow of a 27-year-old man]. MMW Fortschritte der Medizin 20040610
Prediction of the bonding states of cysteines using the support vector machines based on multiple feature vectors and cysteine state sequences. Proteins 20040601
A combinatorial approach to the synthesis of cystine based organogelators. Journal of peptide science : an official publication of the European Peptide Society 20040601
Structure of Ero1p, source of disulfide bonds for oxidative protein folding in the cell. Cell 20040528
Thermal, chemical, and enzymatic stability of the cyclotide kalata B1: the importance of the cyclic cystine knot. Biochemistry 20040525
Determination of the disulfide bond arrangement of dengue virus NS1 protein. The Journal of biological chemistry 20040514
Effect of thiol antioxidant on body fat and insulin reactivity. Journal of molecular medicine (Berlin, Germany) 20040501
Misfolded proinsulin accumulates in expanded pre-Golgi intermediates and endoplasmic reticulum subdomains in pancreatic beta cells of Akita mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040501
Binding of phlorizin to the C-terminal loop 13 of the Na(+)/glucose cotransporter does not depend on the [560-608] disulfide bond. Archives of biochemistry and biophysics 20040501
The A-superfamily of conotoxins: structural and functional divergence. The Journal of biological chemistry 20040423
Cathepsin L1, the major protease involved in liver fluke (Fasciola hepatica) virulence: propetide cleavage sites and autoactivation of the zymogen secreted from gastrodermal cells. The Journal of biological chemistry 20040423
A bacterial expression system revisited for the recombinant production of cystine-rich plant lipid transfer proteins. Biochemical and biophysical research communications 20040416
An R111C polymorphism in wild turkey cardiac troponin I accompanying the dilated cardiomyopathy-related abnormal splicing variant of cardiac troponin T with potentially compensatory effects. The Journal of biological chemistry 20040402
Cellular protein kinase C isozyme regulation by exogenously delivered physiological disulfides--implications of oxidative protein kinase C regulation to cancer prevention. Carcinogenesis 20040401
Vicinal disulfide bridge conformers by experimental methods and by ab initio and DFT molecular computations. Proteins 20040401
Tarantulas: eight-legged pharmacists and combinatorial chemists. Toxicon : official journal of the International Society on Toxinology 20040401
Stone clustering of patients with cystine urinary stone formation. Urology 20040401
Amino acids and asthma: a case-control study. The European respiratory journal 20040401
Prions: so many fibers, so little infectivity. Trends in biochemical sciences 20040401
Identification on mouse chromosome 8 of new beta-defensin genes with regionally specific expression in the male reproductive organ. The Journal of biological chemistry 20040326
[From gene to disease: cystinosis]. Nederlands tijdschrift voor geneeskunde 20040306
TMX, a human transmembrane oxidoreductase of the thioredoxin family: the possible role in disulfide-linked protein folding in the endoplasmic reticulum. Archives of biochemistry and biophysics 20040301
About thiol derivatization and resolution of basic proteins in two-dimensional electrophoresis. Proteomics 20040301
Assembly of MHC class I peptide complexes from the perspective of disulfide bond formation. Cellular and molecular life sciences : CMLS 20040301
Reduced levels of Abeta 40 and Abeta 42 in brains of smoking controls and Alzheimer's patients. Neurobiology of disease 20040301
Structure-function relationship of the extracellular calcium-sensing receptor. Cell calcium 20040301
Binding site for fungal beta-lactone hymeglusin on cytosolic 3-hydroxy-3-methylglutaryl coenzyme A synthase. Biochimica et biophysica acta 20040227
NF-kappaB-dependent induction of osteoprotegerin by Porphyromonas gingivalis in endothelial cells. Biochemical and biophysical research communications 20040227
Murine Frizzled-1 behaves as an antagonist of the canonical Wnt/beta-catenin signaling. The Journal of biological chemistry 20040213
Aspartate 345 of the dopamine transporter is critical for conformational changes in substrate translocation and cocaine binding. The Journal of biological chemistry 20040213
Modulation of the redox state of tubulin by the glutathione/glutaredoxin reductase system. Biochemical and biophysical research communications 20040206
Differentiation of substrate and non-substrate inhibitors of transport system xc(-): an obligate exchanger of L-glutamate and L-cystine. Neuropharmacology 20040201
Promotion of corneal allograft survival by the induction of oxidative macrophages. Investigative ophthalmology & visual science 20040201
Chemical modification of hamster arylamine N-acetyltransferase 2 with isozyme-selective and nonselective N-arylbromoacetamido reagents. The protein journal 20040201
Positions of disulfide bonds and N-glycosylation site in juvenile hormone binding protein. Archives of biochemistry and biophysics 20040115
L-cystine inhibits aspartate-beta-semialdehyde dehydrogenase by covalently binding to the essential 135Cys of the enzyme. Biochimica et biophysica acta 20040114
Comparative genomic analysis of the eight-membered ring cystine knot-containing bone morphogenetic protein antagonists. Molecular endocrinology (Baltimore, Md.) 20040101
Anaphylactoid reactions to intravenous N-acetylcysteine: a prospective case controlled study. Accident and emergency nursing 20040101
Prevention of radiocontrast nephropathy with N-acetylcysteine in patients with chronic kidney disease: a meta-analysis of randomized, controlled trials. American journal of kidney diseases : the official journal of the National Kidney Foundation 20040101
[Conversion of L-cystine and L-cysteine to taurin by the enzyme systems of liver cells]. Prikladnaia biokhimiia i mikrobiologiia 20040101
'Signature sets', minimal fragment sets for identifying protein disulfide structures with cyanylation-based mass mapping methodology. Journal of proteome research 20040101
PEG-g-poly(GdDTPA-co-L-cystine): a biodegradable macromolecular blood pool contrast agent for MR imaging. Bioconjugate chemistry 20040101
Determination of free and total cyst(e)ine in plasma of dogs and cats. Veterinary clinical pathology 20040101
Nondestructive analysis of urinary calculi using micro computed tomography. BMC urology 20040101
Development of primers specific for LMW-GS genes located on chromosome 1D and molecular characterization of a gene from Glu-D3 complex locus in bread wheat. Hereditas 20040101
Tracing the structure-function relationship of neuroglobin and cytoglobin using resonance Raman and electron paramagnetic resonance spectroscopy. IUBMB life 20040101
[Glutathione: its biosynthesis, induction agents and concentrations in selected diseases]. Medycyna pracy 20040101
Role of disulfide bonds in the structure and activity of human insulin. Molecules and cells 20031231
Solution structure of Alo-3: a new knottin-type antifungal peptide from the insect Acrocinus longimanus. Biochemistry 20031216
Induction of the mitochondrial permeability transition by selenium compounds mediated by oxidation of the protein thiol groups and generation of the superoxide. Biochemical pharmacology 20031215
Homocysteine potentiates calcification of cultured rat aortic smooth muscle cells. Life sciences 20031212
Glutamine and KGF each regulate extracellular thiol/disulfide redox and enhance proliferation in Caco-2 cells. American journal of physiology. Regulatory, integrative and comparative physiology 20031201
Urinary excretion of total cystine and the dibasic amino acids arginine, lysine and ornithine in relation to genetic findings in patients with cystinuria treated with sulfhydryl compounds. Urological research 20031201
Redox regulation of PI3K/Akt and p53 in bovine aortic endothelial cells exposed to hydrogen peroxide. Antioxidants & redox signaling 20031201
Evaluation of synchronous twin pulse technique for shock wave lithotripsy: determination of optimal parameters for in vitro stone fragmentation. The Journal of urology 20031201
Inhibition mechanism of S-adenosylmethionine-induced movement deficits by prenylcysteine analogs. Pharmacology, biochemistry, and behavior 20031201
Studies of urinary cystine precipitation in vitro: ontogeny of cystine nephrolithiasis and identification of meso-2,3-dimercaptosuccinic acid as a potential therapy for cystinuria. Molecular genetics and metabolism 20031201
N-acetylcysteine does not prevent bronchopulmonary dysplasia in immature infants: a randomized controlled trial. The Journal of pediatrics 20031201
Comparison of the performance of selenite cystine and mannitol selenite enrichment broths in the isolation of Salmonella spp. from faeces. Communicable disease and public health 20031201
Spatial and dynamic interactions between phospholamban and the canine cardiac Ca2+ pump revealed with use of heterobifunctional cross-linking agents. The Journal of biological chemistry 20031128
Evidence for cystine clustering in thermophilic proteomes. Trends in genetics : TIG 20031101
Epigenetic silencing of the HIC-1 gene in human medulloblastomas. Journal of neuropathology and experimental neurology 20031101
Bidirectional modulation of cystine/glutamate exchanger activity in cultured cortical astrocytes. Annals of the New York Academy of Sciences 20031101
Arylamine N-acetyltransferases: covalent modification and inactivation of hamster NAT1 by bromoacetamido derivatives of aniline and 2-aminofluorene. Journal of protein chemistry 20031101
Interacting helical surfaces of the transmembrane segments of subunits a and c' of the yeast V-ATPase defined by disulfide-mediated cross-linking. The Journal of biological chemistry 20031024
Cystine uptake prevents production of hydrogen peroxide by Lactobacillus fermentum BR11. FEMS microbiology letters 20031010
A Schistosoma japonicum very low-density lipoprotein-binding protein. The international journal of biochemistry & cell biology 20031001
Astrocyte-mediated methylmercury neurotoxicity. Biological trace element research 20031001
Characterization of ATPase activity of a hepatitis C virus NS3 helicase domain, and analysis involving mercuric reagents. Journal of biochemistry 20031001
Allosteric alpha 1-adrenoreceptor antagonism by the conopeptide rho-TIA. The Journal of biological chemistry 20030905
The calpain domain of the maize DEK1 protein contains the conserved catalytic triad and functions as a cysteine proteinase. The Journal of biological chemistry 20030905
Expression and regulation of L-cystine transporter, system xc-, in the newly developed rat retinal Müller cell line (TR-MUL). Glia 20030901
Slc7a9-deficient mice develop cystinuria non-I and cystine urolithiasis. Human molecular genetics 20030901
A mouse model for cystinuria type I. Human molecular genetics 20030901
An engineered interdomain disulfide bond stabilizes human blood coagulation factor VIIIa. Journal of thrombosis and haemostasis : JTH 20030901
Automated data interpretation based on the concept of 'negative signature mass' for mass-mapping disulfide structures of cystinyl proteins. Journal of the American Society for Mass Spectrometry 20030901
Evolutionary origin of inhibitor cystine knot peptides. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030901
Disruption of the Cys5-Cys7 disulfide bridge in the platelet glycoprotein Ibbeta prevents the normal maturation and surface exposure of GPIb-IX complexes. Thrombosis and haemostasis 20030901
Methionine and cystine requirements of slow- and fast-feathering male broilers from zero to three weeks of age. Poultry science 20030901
Methionine and cystine requirements of slow- and fast-feathering broiler males from three to six weeks of age. Poultry science 20030901
[Inferior polar nephrectomy for multi-recurrent inferior caliceal cystine lithiasis]. Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20030901
Structure-function analysis of recombinant substrate protein 22 kDa (SP-22). A mitochondrial 2-CYS peroxiredoxin organized as a decameric toroid. The Journal of biological chemistry 20030829
Synthesis of N-acetyl-S-(3-coumarinyl)-cysteine methyl ester and HPLC analysis of urinary coumarin metabolites. Toxicology 20030828
Nanosecond dynamics of the mouse acetylcholinesterase cys69-cys96 omega loop. The Journal of biological chemistry 20030815
Crystal structure of a proteolytically generated functional monoferric C-lobe of bovine lactoferrin at 1.9A resolution. Journal of molecular biology 20030808
The role of cystine knots in collagen folding and stability, part I. Conformational properties of (Pro-Hyp-Gly)5 and (Pro-(4S)-FPro-Gly)5 model trimers with an artificial cystine knot. Chemistry (Weinheim an der Bergstrasse, Germany) 20030804
The role of cystine knots in collagen folding and stability, part II. Conformational properties of (Pro-Hyp-Gly)n model trimers with N- and C-terminal collagen type III cystine knots. Chemistry (Weinheim an der Bergstrasse, Germany) 20030804
Using analytical ultracentrifugation to study compositional variation in vertebrate genomes. European biophysics journal : EBJ 20030801
Effects on in vitro embryo development and intracellular glutathione content of the presence of thiol compounds during maturation of prepubertal goat oocytes. Molecular reproduction and development 20030801
Novel role of vitamin k in preventing oxidative injury to developing oligodendrocytes and neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030702
Cystine crystal volume determination: a useful tool in the management of cystinuric patients. Urological research 20030701
Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse. Nature neuroscience 20030701
Mechanisms by which cysteine can inhibit or promote the oxidation of low density lipoprotein by copper. Atherosclerosis 20030701
Refolding mechanism of ovalbumin: investigation by using a starting urea-denatured disulfide isomer with mispaired CYS367-CYS382. The Journal of biological chemistry 20030627
Theoretical study of nucleophilic substitution at the disulfide bridge of cyclo-l-cystine. The Journal of organic chemistry 20030613
Expression of the activity of cystine/glutamate exchange transporter, system x(c)(-), by xCT and rBAT. Biochemical and biophysical research communications 20030606
Rhodium-catalyzed disulfide exchange reaction. Journal of the American Chemical Society 20030604
Screening of human primary melanocytes of defined melanocortin-1 receptor genotype: pigmentation marker, ultrastructural and UV-survival studies. Pigment cell research 20030601
Association of the 5-HT2c gene with susceptibility and minimum body mass index in anorexia nervosa. Neuroreport 20030506
EPR spectroscopy shows a microtubule-dependent conformational change in the kinesin switch 1 domain. Biophysical journal 20030501
Nephrolithiasis in Cushing's disease: prevalence, etiopathogenesis, and modification after disease cure. The Journal of clinical endocrinology and metabolism 20030501
Homocysteine strongly enhances metal-catalyzed LDL oxidation in the presence of cystine and cysteine. Atherosclerosis 20030501
Inter-domain redox communication in flavoenzymes of the quiescin/sulfhydryl oxidase family: role of a thioredoxin domain in disulfide bond formation. Biochemistry 20030422
N-acetylcysteine infusion alters blood redox status but not time to fatigue during intense exercise in humans. Journal of applied physiology (Bethesda, Md. : 1985) 20030401
Chemical modification of the mitochondrial ornithine/citrulline carrier by SH reagents: effects on the transport activity and transition from carrier to pore-like function. Biochimica et biophysica acta 20030401
Stimulation of prothrombinase activity by the nonapeptide Thr-Trp-Ala-Arg-Asn-Ser-Tyr-Asn-Val, a segment of a plant thionin. Peptides 20030401
Role of cystine transport in intracellular glutathione level and cisplatin resistance in human ovarian cancer cell lines. British journal of cancer 20030324
A new member of plant CS-lyases. A cystine lyase from Arabidopsis thaliana. The Journal of biological chemistry 20030321
Palmitoylation of carboxypeptidase D. Implications for intracellular trafficking. The Journal of biological chemistry 20030314
Heterotypic interactions between transferrin receptor and transferrin receptor 2. Blood 20030301
Regulation of L-cystine transport and intracellular GSH level by a nitric oxide donor in primary cultured rabbit conjunctival epithelial cell layers. Investigative ophthalmology & visual science 20030301
Utilization of different soy products as affected by age in chicks. Poultry science 20030301
Effects of adding some dietary fibers to a cystine diet on the activities of liver antioxidant enzymes and serum enzymes in rats. Bioscience, biotechnology, and biochemistry 20030301
Retinyl esters are the substrate for isomerohydrolase. Biochemistry 20030225
Molecular dynamics simulations of the unfolding mechanism of the catalytic domain from Aspergillus awamori var. X100 glucoamylase. Journal of biomolecular structure & dynamics 20030201
Structure and polymorphism of the principal neutralization site of Thailand HIV-1 isolate. Journal of biomolecular structure & dynamics 20030201
PKC isozyme S-cysteinylation by cystine stimulates the pro-apoptotic isozyme PKC delta and inactivates the oncogenic isozyme PKC epsilon. Carcinogenesis 20030201
Capillary isotachophoresis of cystine in urine with on-line isotachophoresis sample pretreatment. Die Pharmazie 20030201
[Pathophysiology, diagnosis and conservative therapy of non-calcium kidney calculi]. Therapeutische Umschau. Revue therapeutique 20030201
Functional cooperation of epithelial heteromeric amino acid transporters expressed in madin-darby canine kidney cells. The Journal of biological chemistry 20030110
Snapshots of the cystine lyase C-DES during catalysis. Studies in solution and in the crystalline state. The Journal of biological chemistry 20030103
Durability of the medical management of cystinuria. The Journal of urology 20030101
Quantitation and location of disulfide bonds in proteins. Methods in molecular biology (Clifton, N.J.) 20030101
Vitamin C inhibits diethylmaleate-induced L-cystine transport in human vascular smooth muscle cells. Free radical biology & medicine 20030101
Nutritional evaluation of dried tomato seeds. Poultry science 20030101
[Cystinosis: from cystine crystals to the cystinosin]. Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20030101
Structural and functional properties of IL-4delta2, an alternative splice variant of human IL-4. Journal of proteome research 20030101
The antiatherogenic effect of DiNAC: experimental findings supporting immunomodulation as a new treatment for atherosclerosis related diseases. Cardiovascular drug reviews 20030101
Role of gamma-glutamyltransferase in the homeostasis of glutathione during oxidative and nitrosative stress. BioFactors (Oxford, England) 20030101
Subcycling PCR for long-distance amplifications of regions with high and low guanine-cystine content: amplification of the intron 22 inversion of the FVIII gene. Methods in molecular biology (Clifton, N.J.) 20030101
Understanding base-assisted desulfurization using a variety of disulfide-bridged peptides. Biopolymers 20030101
Suppression of cystine uptake by sulfasalazine inhibits proliferation of human mammary carcinoma cells. Anticancer research 20030101
Orientation and motion of myosin light chain and troponin in reconstituted muscle fibers as detected by ESR with a new bifunctional spin label. Advances in experimental medicine and biology 20030101
A huge bladder cystine stone. International urology and nephrology 20030101
Correlations of cationic charges with salt sensitivity and microbial specificity of cystine-stabilized beta -strand antimicrobial peptides. The Journal of biological chemistry 20021227
Structural basis of BMP signalling inhibition by the cystine knot protein Noggin. Nature 20021212
Polyethylene glycol conjugation at Cys232 prolongs the half-life of alpha1 proteinase inhibitor. American journal of respiratory cell and molecular biology 20021201
Extracellular thiol/disulfide redox state affects proliferation rate in a human colon carcinoma (Caco2) cell line. Free radical biology & medicine 20021201
Medical evaluation of nephrolithiasis. Endocrinology and metabolism clinics of North America 20021201
S-nitrosocysteine and cystine from reaction of cysteine with nitrous acid. A kinetic investigation. The Journal of organic chemistry 20021129
Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression. The Journal of biological chemistry 20021122
Purification, characterization and identification of cysteine desulfhydrase of Corynebacterium glutamicum, and its relationship to cysteine production. FEMS microbiology letters 20021119
Renaturation of human proinsulin--a study on refolding and conversion to insulin. Analytical biochemistry 20021115
Production of intracellular 35S-glutathione by rat and human hepatocytes for the quantification of xenobiotic reactive intermediates. Chemico-biological interactions 20021110
Structure of a novel P-superfamily spasmodic conotoxin reveals an inhibitory cystine knot motif. The Journal of biological chemistry 20021108
The cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor. The Journal of biological chemistry 20021108
Toward synthetic analogues of linked redox and catalytic multimetal sites in proteins: a model of the histidine-cysteine bridged dicopper array. Inorganic chemistry 20021104
Roles of disulfide bridges in scorpion toxin BmK M1 analyzed by mutagenesis. The journal of peptide research : official journal of the American Peptide Society 20021101
Modulation of group II metabotropic glutamate receptor signaling by chronic cocaine. The Journal of pharmacology and experimental therapeutics 20021101
Cystinosis: from gene to disease. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20021101
Preventing kidney stones: calcium restriction not warranted. Cleveland Clinic journal of medicine 20021101
Mouse methionine sulfoxide reductase B: effect of selenocysteine incorporation on its activity and expression of the seleno-containing enzyme in bacterial and mammalian cells. Biochemical and biophysical research communications 20021004
Skin colour and skin cancer - MC1R, the genetic link. Melanoma research 20021001
Characterization of selenium species in Brazil nuts by HPLC-ICP-MS and ES-MS. Journal of agricultural and food chemistry 20020925
Role of disulfide bonds in folding and activity of leiurotoxin I: just two disulfides suffice. Biochemistry 20020924
The [Lys(-2)-Arg(-1)-des(17-21)]-endothelin-1 peptide retains the specific Arg(-1)-Asp8 salt bridge but reveals discrepancies between NMR data and molecular dynamics simulations. Biochemistry 20020917
The light subunit of system b(o,+) is fully functional in the absence of the heavy subunit. The EMBO journal 20020916
Disruption of the long-range GPIIIa Cys(5)-Cys(435) disulfide bond results in the production of constitutively active GPIIb-IIIa (alpha(IIb)beta(3)) integrin complexes. Blood 20020915
Discrimination between mono- and trimethylated cap structures by two isoforms of Caenorhabditis elegans eIF4E. The EMBO journal 20020902
rBAT-b(0,+)AT heterodimer is the main apical reabsorption system for cystine in the kidney. American journal of physiology. Renal physiology 20020901
Potential involvement of copper and thiol-disulphide interchange in prion proteins' conformational conversion. Medical hypotheses 20020901
Crystalline histiocytosis in hereditary cysinosis. Archives of pathology & laboratory medicine 20020901
Roles of endogenous glutathione levels on 6-hydroxydopamine-induced apoptotic neuronal cell death in human neuroblastoma SK-N-SH cells. Neuropharmacology 20020901
[Optimal conditions for determination of L-cystine using capillary isotachophoresis]. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20020901
Intracellular redox regulation by a cystine derivative suppresses UV-induced NF-kappa B activation. FEBS letters 20020828
Simple classification of renal calculi closely related to their micromorphology and etiology. Clinica chimica acta; international journal of clinical chemistry 20020801
Inhibition of Na(+)-dependent transporters in cystine-loaded human renal cells: electrophysiological studies on the Fanconi syndrome of cystinosis. Journal of the American Society of Nephrology : JASN 20020801
Cellular uptake of antisense oligonucleotides after complexing or conjugation with cell-penetrating model peptides. European journal of biochemistry 20020801
Enzymatic properties of a new peptide deformylase from pathogenic bacterium Leptospira interrogans. Biochemical and biophysical research communications 20020726
Solid-phase extraction for the simultaneous preconcentration of organic (selenocystine) and inorganic [Se(IV), Se(VI)] selenium in natural waters. Journal of chromatography. A 20020719
Cystinosis. The New England journal of medicine 20020711
The impact of cystinuria on renal function. The Journal of urology 20020701
Apical heterodimeric cystine and cationic amino acid transporter expressed in MDCK cells. American journal of physiology. Renal physiology 20020701
Enhancement of L-cystine transport activity and its relation to xCT gene induction at the blood-brain barrier by diethyl maleate treatment. The Journal of pharmacology and experimental therapeutics 20020701
Cysteine-mediated electron transfer in syntrophic acetate oxidation by cocultures of Geobacter sulfurreducens and Wolinella succinogenes. Archives of microbiology 20020701
Cerebral cystine uptake: a tale of two transporters. Trends in pharmacological sciences 20020701
Cerebral vasculature is the major target of oxidative protein alterations in bacterial meningitis. Journal of neuropathology and experimental neurology 20020701
[Electrochemical reduction of pentaerythrityltetranitrate (PETN) and metabolites]. Die Pharmazie 20020701
Beare-Stevenson cutis gyrata syndrome with Chiari malformation. Acta neurochirurgica 20020701
Design, pharmacology, and NMR structure of a minimized cystine knot with agouti-related protein activity. Biochemistry 20020618
Analysis of the roles of amino acid residues in the flavoprotein tryptophan 2-monooxygenase modified by 2-oxo-3-pentynoate: characterization of His338, Cys339, and Cys511 mutant enzymes. Archives of biochemistry and biophysics 20020601
Cystine transport activity of heterozygous rBAT mutants expressed in Xenopus oocytes. Nephron 20020601
Specificity of resistance to oxidative stress. Journal of neurochemistry 20020601
Expression of a streptococcal glucosyltransferase as a fusion to a solute-binding protein in Lactobacillus fermentum BR11. FEMS microbiology letters 20020521
Role of individual disulfide bonds in hen lysozyme early folding steps. Protein science : a publication of the Protein Society 20020501
Immunomodulation with DiNAC-- a new approach to the treatment of atherosclerosis? Expert opinion on investigational drugs 20020501
Plasma cystine concentration and redox state in aging and physical exercise. Mechanisms of ageing and development 20020501
Ru(II)-catalyzed cascade reactions in stereocontrolled construction of rigid as-indacene-bridged bis(alpha-amino acid) derivatives. The Journal of organic chemistry 20020419
Exogenous cysteine and cystine promote cell proliferation in CaCo-2 cells. Cell proliferation 20020401
gamma-Glutamyl transpeptidase and glutathione biosynthesis in non-tumorigenic and tumorigenic rat liver oval cell lines. Carcinogenesis 20020401
Solution structures of the cis- and trans-Pro30 isomers of a novel 38-residue toxin from the venom of Hadronyche Infensa sp. that contains a cystine-knot motif within its four disulfide bonds. Biochemistry 20020312
The Tim9p-Tim10p complex binds to the transmembrane domains of the ADP/ATP carrier. The EMBO journal 20020301
Induction of xCT gene expression and L-cystine transport activity by diethyl maleate at the inner blood-retinal barrier. Investigative ophthalmology & visual science 20020301
Promoting effect of beta-mercaptoethanol on in vitro development under oxidative stress and cystine uptake of bovine embryos. Biology of reproduction 20020301
Facile formation of chiral calixarene analogs incorporating cystine peptide into the macrocyclic ring. Chemical & pharmaceutical bulletin 20020301
Increased rate of glutathione synthesis from cystine in drug-resistant MCF-7 cells. Biochemical pharmacology 20020301
Molecular dynamics simulations as a tool for improving protein stability. Protein engineering 20020301
Antibacterial activities and conformations of synthetic alpha-defensin HNP-1 and analogs with one, two and three disulfide bridges. The journal of peptide research : official journal of the American Peptide Society 20020301
Solution structure and dynamics of melanoma inhibitory activity protein. Journal of biomolecular NMR 20020301
Hyperhomocyst(e)inemia induces accelerated transplant vascular sclerosis in syngeneic and allogeneic rat cardiac transplants. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20020301
Disulfide bond assignments of secreted Frizzled-related protein-1 provide insights about Frizzled homology and netrin modules. The Journal of biological chemistry 20020215
Structural requirements for palmitoylation of surfactant protein C precursor. The Biochemical journal 20020201
Identification of structural motifs and amino acids within the structure of human heparan sulfate 3-O-sulfotransferase that mediate enzymatic function. Biochemical and biophysical research communications 20020201
Analysis of cystine in human blood for monitoring of cases of burns. Journal of pharmaceutical and biomedical analysis 20020201
Structure motif discovery and mining the PDB. Bioinformatics (Oxford, England) 20020201
The solution structure of gomesin, an antimicrobial cysteine-rich peptide from the spider. European journal of biochemistry 20020201
Stabilization of a (betaalpha)8-barrel protein by an engineered disulfide bridge. European journal of biochemistry 20020201
Amino acid concentrations in the blood of the jugular vein and peripheral artery after traumatic brain injury: decreased release of glutamate into the jugular vein in the early phase. Journal of neurotrauma 20020201
Evaluation of circulating levels and renal clearance of natural amino acids in patients with Cushing's disease. Journal of endocrinological investigation 20020201
Functional implications of post-translational modifications of phospholipases D1 and D2. Biochimica et biophysica acta 20020130
New monomeric cobalt(II) and zinc(II) complexes of a mixed N,S(alkylthiolate) ligand: model complexes of (His)(His)(Cys) metalloprotein active sites. Inorganic chemistry 20020128
Redox regulation of cytosolic glycerol-3-phosphate dehydrogenase: Cys(102) is the target of the redox control and essential for the catalytic activity. Biochimica et biophysica acta 20020115
Cystine: a promoter of the growth and aggregation of calcium oxalate crystals in normal undiluted human urine. The Journal of urology 20020101
Melatoninergic neuroprotection of the murine periventricular white matter against neonatal excitotoxic challenge. Annals of neurology 20020101
Male fertility is compatible with an Arg(840)Cys substitution in the AR in a large Chinese family affected with divergent phenotypes of AR insensitivity syndrome. The Journal of clinical endocrinology and metabolism 20020101
The amino acid requirements of Corynebacterium diphtheriae PW 8 substrain CN 2000. Journal of applied microbiology 20020101
Association of changes in the pattern of urinary calculi in Taiwanese with diet habit change between 1956 and 1999. Journal of the Formosan Medical Association = Taiwan yi zhi 20020101
A degradation study of a series of chloromethyl and diazomethyl ketone anti-leukemic agents. Drug development and industrial pharmacy 20020101
Mitogen activated protein kinase activation and oxidant signaling in astrocytoma cells. Journal of neuro-oncology 20020101
A switch in disulfide linkage during minicollagen assembly in hydra nematocysts or how to assemble a 150-bar-resistant structure. Journal of structural biology 20020101
Cystine/glutamate exchange serves as the source for extracellular glutamate: modifications by repeated cocaine administration. Amino acids 20020101
Nephropathic cystinosis associated with cardiomyopathy: a 27-year clinical follow-up. BMC nephrology 20020101
Cathepsin B stability, but not activity, is affected in cysteine:cystine redox buffers. Biological chemistry 20020101
Dissociations of disulfide-linked gaseous polypeptide/protein anions: ion chemistry with implications for protein identification and characterization. Journal of proteome research 20020101
Extracorporeal shock wave lithotripsy for cystine urolithiasis in children: outcome and complications. International urology and nephrology 20020101
Role of glutamate transporters in the regulation of glutathione levels in human macrophages. American journal of physiology. Cell physiology 20011201
Cargo delivery kinetics of cell-penetrating peptides. Biochimica et biophysica acta 20011201
A normal rate of cellular cholesterol removal can be mediated by plasma from a patient with familial lecithin-cholesterol acyltransferase (LCAT) deficiency. Clinica chimica acta; international journal of clinical chemistry 20011201
Determination of pyrophosphate in renal calculi and urine by means of an enzymatic method. Clinica chimica acta; international journal of clinical chemistry 20011201
Identification and characterization of uptake systems for cystine and cysteine in cultured astrocytes and neurons: evidence for methylmercury-targeted disruption of astrocyte transport. Journal of neuroscience research 20011201
Gamma-glutamyl transpeptidase and glutathione biosynthesis in non-tumorigenic and tumorigenic rat liver oval cell lines. Carcinogenesis 20011201
Defect of heparin binding in plasma and recombinant von Willebrand factor with type 2 von Willebrand disease mutations. Thrombosis and haemostasis 20011201
Transport measurements across Caco-2 monolayers of different organic and inorganic selenium: influence of sulfur compounds. Biological trace element research 20011201
Sequential comparison of peptides containing half-cystine residues from ovalbumins of six avian species. Bioscience, biotechnology, and biochemistry 20011201
Type 1 von Willebrand disease mutation Cys1149Arg causes intracellular retention and degradation of heterodimers: a possible general mechanism for dominant mutations of oligomeric proteins. Blood 20011115
Cystinosin, the protein defective in cystinosis, is a H(+)-driven lysosomal cystine transporter. The EMBO journal 20011101
Glutamate induces oxidative stress not mediated by glutamate receptors or cystine transporters: protective effect of melatonin and other antioxidants. Journal of pineal research 20011101
Molecular mechanisms of cystine transport. Biochemical Society transactions 20011101
[Development of selective antagonists against an HIV second receptor]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20011101
[Cystinuria and cystine kidney lithiasis. Diagnosis and therapeutic approach]. Archivos espanoles de urologia 20011101
Thiol-disulfide exchange between nuclear-encoded and chloroplast-encoded subunits of pea acetyl-CoA carboxylase. The Journal of biological chemistry 20011026
Demonstration of a cystine unit as a promising turn scaffold for the design of a parallel U-shaped two-helix bundle motif: crystal structure of the homodimer Cys(Aib(n))(2) (n = 3, 4). Biopolymers 20011015
N,N'-diacetyl-L-cystine (DiNAC), the disulphide dimer of N-acetylcysteine, inhibits atherosclerosis in WHHL rabbits: evidence for immunomodulatory agents as a new approach to prevent atherosclerosis. The Journal of pharmacology and experimental therapeutics 20011001
Oxidative glutamate toxicity can be a component of the excitotoxicity cascade. The Journal of neuroscience : the official journal of the Society for Neuroscience 20011001
IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding. The EMBO journal 20011001
N-acetylcysteine increases cerebral perfusion pressure in pigs with fulminant hepatic failure. Critical care medicine 20011001
Ocular findings among patients with late-diagnosed or poorly controlled homocystinuria compared with a screened, well-controlled population. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20011001
Mucus fishing syndrome: case report and new treatment option. Optometry (St. Louis, Mo.) 20011001
Activation of carrier-mediated transport of L-cystine at the blood-brain and blood-retinal barriers in vivo. Microvascular research 20010901
The molecular basis of Dutch infantile nephropathic cystinosis. Nephron 20010901
CSTX-9, a toxic peptide from the spider Cupiennius salei: amino acid sequence, disulphide bridge pattern and comparison with other spider toxins containing the cystine knot structure. Cellular and molecular life sciences : CMLS 20010901
Structural analysis of free and enzyme-bound amaranth alpha-amylase inhibitor: classification within the knottin fold superfamily and analysis of its functional flexibility. Protein engineering 20010901
Kinetics in the pre-steady state of the formation of cystines in ribonucleoside diphosphate reductase: evidence for an asymmetric complex. Biochemistry 20010814
Solution structure of the satiety factor, CART, reveals new functionality of a well-known fold. Biochemistry 20010807
Location and mechanism of alpha 2,6-sialyltransferase dimer formation. Role of cysteine residues in enzyme dimerization, localization, activity, and processing. The Journal of biological chemistry 20010803
Urinary sulfur compounds in Down syndrome. Clinical chemistry 20010801
Hounsfield unit density in the determination of urinary stone composition. Urology 20010801
The intellectual abilities of early-treated individuals with pyridoxine-nonresponsive homocystinuria due to cystathionine beta-synthase deficiency. Journal of inherited metabolic disease 20010801
Metabolism of S-nitrosoglutathione by endothelial cells. American journal of physiology. Heart and circulatory physiology 20010701
Role of the cystine-knot motif at the C-terminus of rat mucin protein Muc2 in dimer formation and secretion. The Biochemical journal 20010701
Medical and surgical therapy of the cystine stone patient. Current opinion in urology 20010701
Laminar distribution of nicotinic receptor subtypes in cortical regions in schizophrenia. Journal of chemical neuroanatomy 20010701
Determination of amino acids by ion-exchange chromatography on filter paper spotted blood samples stored at different temperatures and for different periods: comparison with capillary and venous blood. Clinical biochemistry 20010701
Monitoring of the subtraction process in solid-phase representational difference analysis: characterization of a candidate drug. Gene 20010627
Self-assembling, cystine-derived, fused nanotubes based on spirane architecture: design, synthesis, and crystal structure of cystinospiranes. Journal of the American Chemical Society 20010620
Partial restoration of lutropin activity by an intersubunit disulfide bond: implications for structure/function studies. Experimental biology and medicine (Maywood, N.J.) 20010601
Estimation of the total sulfur amino acid requirement and the effect of betaine in diets deficient in total sulfur amino acids for the weanling pig. Journal of animal science 20010601
Effect of fudosteine, a new cysteine derivative, on mucociliary transport. The Journal of pharmacy and pharmacology 20010601
Synthesis of diaminosuberic acid derivatives via ring-closing alkyne metathesis. The Journal of organic chemistry 20010518
Evolution and classification of cystine knot-containing hormones and related extracellular signaling molecules. Molecular endocrinology (Baltimore, Md.) 20010501
The metabolism of sulphur in relation to the biochemistry of cystine and cysteine: its fundamental importance in biology. A cyclic interchange between their mono- and di-sulphides is the unique reaction creating life and intelligence. Medical hypotheses 20010501
A new strategy for the synthesis of cyclopeptides containing diaminoglutaric acid. Journal of peptide science : an official publication of the European Peptide Society 20010501
xCt cystine transporter expression in HEK293 cells: pharmacology and localization. Biochemical and biophysical research communications 20010420
Functional contributions of noncysteine residues within the cystine knots of human chorionic gonadotropin subunits. The Journal of biological chemistry 20010406
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