Acetamide,N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-
Title | Journal |
---|---|
Investigation of belinostat-induced genomic instability by molecular cytogenetic analysis and pathway-focused gene expression profiling. | Toxicology and applied pharmacology 20180701 |
Profiling the immunotoxicity of chemicals based on in vitro evaluation by a combination of the Multi-ImmunoTox assay and the IL-8 Luc assay. | Archives of toxicology 20180601 |
In vitro safety and efficacy evaluations of a complex botanical mixture of Eugenia dysenterica DC. (Myrtaceae): Prospects for developing a new dermocosmetic product. | Toxicology in vitro : an international journal published in association with BIBRA 20171201 |
Why are most phospholipidosis inducers also hERG blockers? | Archives of toxicology 20171201 |
From the Cover: Does the Assessment of Nondisjunction Provide a More Sensitive Assay for the Detection of Aneugens? | Toxicological sciences : an official journal of the Society of Toxicology 20170501 |
Zinc deficiency affects the STAT1/3 signaling pathways in part through redox-mediated mechanisms. | Redox biology 20170401 |
High-content imaging-based BAC-GFP toxicity pathway reporters to assess chemical adversity liabilities. | Archives of toxicology 20170101 |
Activated charcoal significantly reduces the amount of colchicine released from Gloriosa superba in simulated gastric and intestinal media. | Clinical toxicology (Philadelphia, Pa.) 20170101 |
CWF-145, a novel synthetic quinolone derivative exerts potent antimitotic activity against human prostate cancer: Rapamycin enhances antimitotic drug-induced apoptosis through the inhibition of Akt/mTOR pathway. | Chemico-biological interactions 20161225 |
Discovery of a Highly Selective STK16 Kinase Inhibitor. | ACS chemical biology 20160617 |
Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices. | Chemical research in toxicology 20160321 |
Expression of basolateral organic anion and cation transporters in experimental cadmium nephrotoxicity in rat kidney. | Archives of toxicology 20160301 |
An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death. | The Journal of biological chemistry 20150821 |
Utilization of human nuclear receptors as an early counter screen for off-target activity: a case study with a compendium of 615 known drugs. | Toxicological sciences : an official journal of the Society of Toxicology 20150601 |
Population-based in vitro hazard and concentration-response assessment of chemicals: the 1000 genomes high-throughput screening study. | Environmental health perspectives 20150501 |
Evaluation of the Multi-ImmunoTox Assay composed of 3 human cytokine reporter cells by examining immunological effects of drugs. | Toxicology in vitro : an international journal published in association with BIBRA 20140801 |
Colchicine effect on P-glycoprotein expression and activity: in silico and in vitro studies. | Chemico-biological interactions 20140725 |
Synthesis of a novel legumain-cleavable colchicine prodrug with cell-specific toxicity. | Bioorganic & medicinal chemistry 20140701 |
Utilization of CDKN1A/p21 gene for class discrimination of DNA damage-induced clastogenicity. | Toxicology 20140106 |
Quantitative high-throughput profiling of environmental chemicals and drugs that modulate farnesoid X receptor. | Scientific reports 20140101 |
4-Acyl pyrroles: mimicking acetylated lysines in histone code reading. | Angewandte Chemie (International ed. in English) 20131223 |
Evaluation of aggregating brain cell cultures for the detection of acute organ-specific toxicity. | Toxicology in vitro : an international journal published in association with BIBRA 20130601 |
Puerarin mediates hepatoprotection against CCl4-induced hepatic fibrosis rats through attenuation of inflammation response and amelioration of metabolic function. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20130201 |
Chemotherapy drugs form ion pores in membranes due to physical interactions with lipids. | Chemical biology & drug design 20121201 |
Synthesis and biological evaluation of novel heterocyclic derivatives of combretastatin A-4. | Bioorganic & medicinal chemistry letters 20121201 |
Gender differences in the liver micronucleus test in rats with partial hepatectomy. | Toxicology letters 20121115 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine. | Bioorganic & medicinal chemistry 20121115 |
Novel tubulin polymerization inhibitors overcome multidrug resistance and reduce melanoma lung metastasis. | Pharmaceutical research 20121101 |
Vasopressin-2 receptor antagonist attenuates the ability of the lungs to clear edema in an experimental model. | American journal of respiratory cell and molecular biology 20121101 |
Orally bioavailable tubulin antagonists for paclitaxel-refractory cancer. | Pharmaceutical research 20121101 |
Microtubules and angiotensin II receptors contribute to modulation of repolarization induced by ventricular pacing. | Heart rhythm 20121101 |
Assessment of the association between colchicine therapy and serious adverse events. | Pharmacotherapy 20121101 |
Synthesis and biological evaluation of a series of podophyllotoxins derivatives as a class of potent antitubulin agents. | Bioorganic & medicinal chemistry 20121101 |
Initiation of allopurinol at first medical contact for acute attacks of gout: a randomized clinical trial. | The American journal of medicine 20121101 |
Discovery of novel tubulin inhibitors via structure-based hierarchical virtual screening. | Journal of chemical information and modeling 20121022 |
Treatment of chronic gouty arthritis: it is not just about urate-lowering therapy. | Seminars in arthritis and rheumatism 20121001 |
Challenges associated with the management of gouty arthritis in patients with chronic kidney disease: a systematic review. | Seminars in arthritis and rheumatism 20121001 |
Differential effects of colchicine in blood mononuclear cells of patients with Behçet disease in relation to colchicine responsiveness. | The British journal of dermatology 20121001 |
Potential unmet need for gout diagnosis and treatment: capture-recapture analysis of a national administrative dataset. | Rheumatology (Oxford, England) 20121001 |
Mean platelet volume and β-thromboglobulin levels in familial Mediterranean fever: effect of colchicine use? | European journal of internal medicine 20121001 |
Intestinal amyloidosis with intractable diarrhea and intestinal pseudo-obstruction. | The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20120925 |
Total synthesis of indole-derived allocolchicine analogues exhibiting strong apoptosis-inducing activity. | Chemistry (Weinheim an der Bergstrasse, Germany) 20120917 |
Myopathy and possible intestinal dysfunction in a patient treated with colchicine and simvastatin. | The Medical journal of Australia 20120917 |
Rab6-mediated retrograde transport regulates inner nuclear membrane targeting of caveolin-2 in response to insulin. | Traffic (Copenhagen, Denmark) 20120901 |
Comparative evaluation of small-molecule chemosensitizers in reversal of cisplatin resistance in ovarian cancer cells. | Anticancer research 20120901 |
Structural and numerical chromosome aberration inducers in liver micronucleus test in rats with partial hepatectomy. | Mutation research 20120830 |
Interactive medical case. Disconnected. | The New England journal of medicine 20120816 |
Interaction of pseudolaric acid B with the colchicine site of tubulin. | Biochemical pharmacology 20120815 |
Colchicine-induced apoptosis in human normal liver L-02 cells by mitochondrial mediated pathways. | Toxicology in vitro : an international journal published in association with BIBRA 20120801 |
Renal transplantation in patients with familial Mediterranean fever. | Clinical rheumatology 20120801 |
The effect of thiocolchicoside on cerebral vasospasm following experimental subarachnoid hemorrhage in the rabbit. | Acta neurochirurgica 20120801 |
Casebook consults: improving outcomes in gout (multimedia activity). | The American journal of medicine 20120801 |
The unwelcome visitor. | Singapore medical journal 20120801 |
Synthesis and structure-activity relationships of benzophenone-bearing diketopiperazine-type anti-microtubule agents. | Bioorganic & medicinal chemistry 20120715 |
Protective effect of Fufang-Liu-Yue-Qing, a traditional Chinese herbal formula, on CCl4 induced liver fibrosis in rats. | Journal of ethnopharmacology 20120713 |
Behcet's disease and IgA nephropathy. | Rheumatology international 20120701 |
Protective role of curcumin on colchicine-induced cognitive dysfunction and oxidative stress in rats. | Human & experimental toxicology 20120701 |
New substituted 4H-chromenes as anticancer agents. | Bioorganic & medicinal chemistry letters 20120701 |
Colchicine use is associated with decreased prevalence of myocardial infarction in patients with gout. | The Journal of rheumatology 20120701 |
Synthesis, characterization and in vitro anti-tumor activities of matrine derivatives. | Bioorganic & medicinal chemistry letters 20120615 |
Clinical response to thalidomide and colchicine in two siblings with Behcet's disease carrying a single mutated MEFV allele. | Rheumatology international 20120601 |
Neuroprotection by nicotine against colchicine-induced apoptosis is mediated by PI3-kinase--Akt pathways. | The International journal of neuroscience 20120601 |
Protective effect of isoorientin-2″-O-α-L-arabinopyranosyl isolated from Gypsophila elegans on alcohol induced hepatic fibrosis in rats. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120601 |
N⁴-Phenyl-substituted 2-acetylpyridine thiosemicarbazones: cytotoxicity against human tumor cells, structure-activity relationship studies and investigation on the mechanism of action. | Bioorganic & medicinal chemistry 20120601 |
Reversing ABCB1-mediated multi-drug resistance from within cells using translocating immune conjugates. | Journal of drug targeting 20120601 |
Are dosing adjustments required for colchicine in the elderly compared with younger patients? | Advances in therapy 20120601 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. | Journal of medicinal chemistry 20120524 |
Design, synthesis and biological evaluation of novel chalcone derivatives as antitubulin agents. | Bioorganic & medicinal chemistry 20120515 |
Synthesis, biological evaluation, and molecular docking studies of 2,6-dinitro-4-(trifluoromethyl)phenoxysalicylaldoxime derivatives as novel antitubulin agents. | Bioorganic & medicinal chemistry 20120515 |
Recent advances in management of gout. | QJM : monthly journal of the Association of Physicians 20120501 |
National prevalence of gout derived from administrative health data in Aotearoa New Zealand. | Rheumatology (Oxford, England) 20120501 |
Discovery of small molecule inhibitors that interact with γ-tubulin. | Chemical biology & drug design 20120501 |
Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs. | Toxicological sciences : an official journal of the Society of Toxicology 20120501 |
Fluorescent protein-labeled glucocorticoid receptor alpha isoform trafficking in cultured human trabecular meshwork cells. | Investigative ophthalmology & visual science 20120501 |
G-protein-gated inwardly rectifying K+ channel 4 (GIRK4) immunoreactivity in chemically defined neurons of the hypothalamic arcuate nucleus that control body weight. | Journal of chemical neuroanatomy 20120501 |
Immunotherapies in rheumatologic disorders. | The Medical clinics of North America 20120501 |
[The role of aldosterone and IL-6 in the pathogenesis of inflammation in familial Mediterranean fever]. | Georgian medical news 20120501 |
A case of Behçet's disease treated with a humanized anti-interleukin-6 receptor antibody, tocilizumab. | Modern rheumatology 20120401 |
Thiocolchicoside suppresses osteoclastogenesis induced by RANKL and cancer cells through inhibition of inflammatory pathways: a new use for an old drug. | British journal of pharmacology 20120401 |
Thiocolchicoside a semi-synthetic derivative of the Glory Lily: a new weapon to fight metastatic bone resorption? | British journal of pharmacology 20120401 |
[Death following administration of pristinamycine and colchicine]. | Presse medicale (Paris, France : 1983) 20120401 |
Gout and organ transplantation. | Current rheumatology reports 20120401 |
Colchicine affects cell motility, pattern formation and stalk cell differentiation in Dictyostelium by altering calcium signaling. | Differentiation; research in biological diversity 20120401 |
High fat diet impact on Fos expression in ovariectomized female C57BL/6 mice: effect of colchicine and response of different neuronal phenotypes. | Endocrine regulations 20120401 |
Autoinflammatory syndromes. | Pediatric clinics of North America 20120401 |
Liposomes as carriers for colchicine-derived prodrugs: vascular disrupting nanomedicines with tailorable drug release kinetics. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120312 |
Substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones and analogues: synthesis, cytotoxic activity, and study of the mechanism of action. | Journal of medicinal chemistry 20120308 |
Forced degradation study of thiocolchicoside: characterization of its degradation products. | Journal of pharmaceutical and biomedical analysis 20120305 |
An infant with severe refractory Crohn's disease and homozygous MEFV mutation who dramatically responded to colchicine. | Rheumatology international 20120301 |
Transient involvement of the cerebral cortex in a flare of Behçet's syndrome. | Rheumatology international 20120301 |
Study of planarian stem cell proliferation by means of flow cytometry. | Molecular biology reports 20120301 |
Eosinophilic fasciitis (Shulman disease): new insights into the therapeutic management from a series of 34 patients. | Rheumatology (Oxford, England) 20120301 |
Polygamain, a new microtubule depolymerizing agent that occupies a unique pharmacophore in the colchicine site. | Molecular pharmacology 20120301 |
Gout: what a pain in the neck. | Connecticut medicine 20120301 |
Neuronal localization of 5-HT2A receptor immunoreactivity in the rat hippocampal region. | Brain research bulletin 20120210 |
Synthesis and structure-activity relationship study of antimicrotubule agents phenylahistin derivatives with a didehydropiperazine-2,5-dione structure. | Journal of medicinal chemistry 20120209 |
3-substituted 2-phenylimidazo[2,1-b]benzothiazoles: synthesis, anticancer activity, and inhibition of tubulin polymerization. | ChemMedChem 20120206 |
Salinomycin sensitizes antimitotic drugs-treated cancer cells by increasing apoptosis via the prevention of G2 arrest. | Biochemical and biophysical research communications 20120203 |
Synthesis and biological evaluation of 2-amino-1-thiazolyl imidazoles as orally active anticancer agents. | Investigational new drugs 20120201 |
Synthesis, biological evaluation, and molecular docking studies of cinnamic acyl 1,3,4-thiadiazole amide derivatives as novel antitubulin agents. | Bioorganic & medicinal chemistry 20120201 |
Nicotine evoked improvement in learning and memory is mediated through NPY Y1 receptors in rat model of Alzheimer's disease. | Peptides 20120201 |
Inflammatory mechanisms and oxidative stress in Peyronie's disease: therapeutic 'rationale' and related emerging treatment strategies. | Inflammation & allergy drug targets 20120201 |
A neurosteroid analogue photolabeling reagent labels the colchicine-binding site on tubulin: a mass spectrometric analysis. | Electrophoresis 20120201 |
Synthesis, biological evaluation and molecular docking studies of resveratrol derivatives possessing curcumin moiety as potent antitubulin agents. | Bioorganic & medicinal chemistry 20120115 |
Design, synthesis, biological evaluation and molecular modeling of 1,3,4-oxadiazoline analogs of combretastatin-A4 as novel antitubulin agents. | Bioorganic & medicinal chemistry 20120115 |
Molecular cytogenetic evaluation of the aneugenic effects of teniposide in somatic and germinal cells of male mice. | Mutagenesis 20120101 |
Effect of colchicine compared with placebo on high sensitivity C-reactive protein in patients with acute coronary syndrome or acute stroke: a pilot randomized controlled trial. | Journal of thrombosis and thrombolysis 20120101 |
Synthetic studies on amaryllidaceae and other terrestrially derived alkaloids. | Topics in current chemistry 20120101 |
Synthesis, molecular docking study and antitumor activity of novel 2-phenylindole derivatives. | European journal of medicinal chemistry 20120101 |
A case of epidermolysis bullosa acquisita associated with laryngeal stenosis. | Acta dermato-venereologica 20120101 |
Cellular growth kinetics distinguish a cyclophilin inhibitor from an HSP90 inhibitor as a selective inhibitor of hepatitis C virus. | PloS one 20120101 |
Efficacy of colchicine in the treatment of mesenteric panniculitis in a young patient. | Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20120101 |
Human cytomegalovirus entry into dendritic cells occurs via a macropinocytosis-like pathway in a pH-independent and cholesterol-dependent manner. | PloS one 20120101 |
An IgE immediate reaction to thiocolchicoside. | International journal of immunopathology and pharmacology 20120101 |
Regulation of organic cation transport in isolated mouse proximal tubules involves complex changes in protein trafficking and substrate affinity. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101 |
Association between the methylene tetrahydrofolate reductase gene C677T mutation and colchicine unresponsiveness in Behcet's disease. | Molecular vision 20120101 |
[A young man with recurrent chest pain]. | Nederlands tijdschrift voor geneeskunde 20120101 |
Therapeutic intervention for chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS): a systematic review and meta-analysis. | PloS one 20120101 |
The reactivity, distribution and abundance of Non-astrocytic Inner Retinal Glial (NIRG) cells are regulated by microglia, acute damage, and IGF1. | PloS one 20120101 |
Chemical investigation of Iphigenia stellata blatter by GC-MS. | Bioorganicheskaia khimiia 20120101 |
To evaluate efficacy and safety of fixed dose combination of aceclofenac + paracetamol + thiocolchicoside (acenac-MR) in the treatment of acute low back pain. | Journal of the Indian Medical Association 20120101 |
Design and synthesis of 2-heterocyclyl-3-arylthio-1H-indoles as potent tubulin polymerization and cell growth inhibitors with improved metabolic stability. | Journal of medicinal chemistry 20111222 |
5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors. Part 2. The impact of bridging groups at position C-2. | Journal of medicinal chemistry 20111222 |
[Pericarditis in an athlete. How long must he abstain from sports?]. | MMW Fortschritte der Medizin 20111208 |
Simple method for culture of peripheral blood lymphocytes of Testudinidae. | Genetics and molecular research : GMR 20111206 |
[Treatment of gout]. | La Revue de medecine interne 20111201 |
[What's new in recurrent pericarditis in 2011?]. | La Revue de medecine interne 20111201 |
A two-stage approach to the treatment of hyperuricemia in gout: the 'dirty dish' hypothesis. | Arthritis and rheumatism 20111201 |
Colchicine modulates oxidative stress in serum and neutrophil of patients with Behçet disease through regulation of Ca²⁺ release and antioxidant system. | The Journal of membrane biology 20111201 |
Behçet disease: clinical features and management in a Brazilian tertiary hospital. | Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20111201 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
A rare case of idiopathic neutrophilic dermatosis of the hands. | Dermatology online journal 20111115 |
Interfacial behavior of immortalized hypothalamic mouse neurons detected by acoustic wave propagation. | The Analyst 20111107 |
Should we routinely evaluate serum alkaline phosphatase levels in patients with gout? | Rheumatology international 20111101 |
The role of Brugia malayi ATP-binding cassette (ABC) transporters in potentiating drug sensitivity. | Parasitology research 20111101 |
Substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonamides as antimitotics. Antiproliferative, antiangiogenic and antitumoral activity, and quantitative structure-activity relationships. | European journal of medicinal chemistry 20111101 |
Acute gout at engraftment following hematopoietic transplantation. | American journal of hematology 20111101 |
Angiotensin II stimulates H⁺-ATPase activity in intercalated cells from isolated mouse connecting tubules and cortical collecting ducts. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20111101 |
Combined occlusal and pharmacological therapy in the treatment of temporo-mandibular disorders. | European review for medical and pharmacological sciences 20111101 |
Design and synthesis of resveratrol-based nitrovinylstilbenes as antimitotic agents. | Journal of medicinal chemistry 20111013 |
Electrochemical oxidation behavior of colchicine on a graphene oxide-Nafion composite film modified glassy carbon electrode. | The Analyst 20111007 |
Synthesis and antitumor molecular mechanism of agents based on amino 2-(3',4',5'-trimethoxybenzoyl)benzo[b]furan: inhibition of tubulin and induction of apoptosis. | ChemMedChem 20111004 |
Neuroanatomical evidence for reciprocal regulation of the corticotrophin-releasing factor and oxytocin systems in the hypothalamus and the bed nucleus of the stria terminalis of the rat: Implications for balancing stress and affect. | Psychoneuroendocrinology 20111001 |
Experimentally confirmed induction of Sweet's syndrome by phototesting. | Acta dermato-venereologica 20111001 |
Pharmacokinetic optimization of 4-substituted methoxybenzoyl-aryl-thiazole and 2-aryl-4-benzoyl-imidazole for improving oral bioavailability. | Drug metabolism and disposition: the biological fate of chemicals 20111001 |
ABC transporters influence sensitivity of Brugia malayi to moxidectin and have potential roles in drug resistance. | Experimental parasitology 20111001 |
Management of epidermolysis bullosa acquisita. | Dermatologic clinics 20111001 |
Effects of anti-tumor necrosis factor agents for familial mediterranean fever patients with chronic arthritis and/or sacroiliitis who were resistant to colchicine treatment. | Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20111001 |
Pericarditis - clinical features and management. | Australian family physician 20111001 |
A case of acute constrictive pericarditis associated with Behçet's disease. | International journal of rheumatic diseases 20111001 |
Albendazole and colchicine modulate LPS-induced secretion of inflammatory mediators by liver macrophages. | Bulletin of experimental biology and medicine 20111001 |
Dynamic changes of acoustic load and complex impedance as reporters for the cytotoxicity of small molecule inhibitors. | Chemical research in toxicology 20110919 |
Synthesis and SAR requirements of adamantane-colchicine conjugates with both microtubule depolymerizing and tubulin clustering activities. | Bioorganic & medicinal chemistry 20110915 |
Discovery of 7-hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a tubulin polymerization inhibitor with potent antiproliferative and tumor vascular disrupting properties. | Journal of medicinal chemistry 20110908 |
Synthesis and biological evaluation of 1-(4'-Indolyl and 6'-Quinolinyl) indoles as a new class of potent anticancer agents. | European journal of medicinal chemistry 20110901 |
Colchicine or methotrexate, with ursodiol, are effective after 20 years in a subset of patients with primary biliary cirrhosis. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20110901 |
3-Aryl-2-[1H-benzotriazol-1-yl]acrylonitriles: a novel class of potent tubulin inhibitors. | European journal of medicinal chemistry 20110901 |
Hyperuricaemia and gout. | The journal of the Royal College of Physicians of Edinburgh 20110901 |
Parvulin 17 promotes microtubule assembly by its peptidyl-prolyl cis/trans isomerase activity. | Journal of molecular biology 20110826 |
Synthesis and antiproliferative activity of novel 2-aryl-4-benzoyl-imidazole derivatives targeting tubulin polymerization. | Bioorganic & medicinal chemistry 20110815 |
A case of granulomatous mastitis with erythema nodosum and arthritis. | Rheumatology international 20110801 |
Behavioural effects of antidepressants are dependent and independent on the integrity of the dentate gyrus. | The international journal of neuropsychopharmacology 20110801 |
The effect of vitamin D3 and ketoconazole combination on VDR-mediated P-gp expression and function in human colon adenocarcinoma cells: implications in drug disposition and resistance. | Basic & clinical pharmacology & toxicology 20110801 |
Novel evidence-based colchicine dose-reduction algorithm to predict and prevent colchicine toxicity in the presence of cytochrome P450 3A4/P-glycoprotein inhibitors. | Arthritis and rheumatism 20110801 |
Discovery of benzimidazole derivatives as novel multi-target EGFR, VEGFR-2 and PDGFR kinase inhibitors. | Bioorganic & medicinal chemistry 20110801 |
Unrecognized fatalities related to colchicine in hospitalized patients. | Clinical toxicology (Philadelphia, Pa.) 20110801 |
Interleukin-1 inhibition by anakinra in refractory chronic tophaceous gout. | International journal of rheumatic diseases 20110801 |
Colchicine prescribing in patients with gout. | The New Zealand medical journal 20110729 |
Convergent synthesis and biological evaluation of 2-amino-4-(3',4',5'-trimethoxyphenyl)-5-aryl thiazoles as microtubule targeting agents. | Journal of medicinal chemistry 20110728 |
Regioselective Suzuki coupling of dihaloheteroaromatic compounds as a rapid strategy to synthesize potent rigid combretastatin analogues. | Journal of medicinal chemistry 20110728 |
Phenylimino-10H-anthracen-9-ones as novel antimicrotubule agents-synthesis, antiproliferative activity and inhibition of tubulin polymerization. | Bioorganic & medicinal chemistry 20110715 |
Design, synthesis, and SAR studies of 4-substituted methoxylbenzoyl-aryl-thiazoles analogues as potent and orally bioavailable anticancer agents. | Journal of medicinal chemistry 20110714 |
Design, synthesis, biological evaluation, and structure-activity relationships of substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new tubulin inhibitors mimicking combretastatin A-4. | Journal of medicinal chemistry 20110714 |
MT119, a new planar-structured compound, targets the colchicine site of tubulin arresting mitosis and inhibiting tumor cell proliferation. | International journal of cancer 20110701 |
Colchicine inhibits cationic dye uptake induced by ATP in P2X2 and P2X7 receptor-expressing cells: implications for its therapeutic action. | British journal of pharmacology 20110701 |
Synthesis, antiproliferative activity, and mechanism of action of a series of 2-{[(2E)-3-phenylprop-2-enoyl]amino}benzamides. | European journal of medicinal chemistry 20110701 |
Canakinumab reduces the risk of acute gouty arthritis flares during initiation of allopurinol treatment: results of a double-blind, randomised study. | Annals of the rheumatic diseases 20110701 |
Effects of borneol on the intestinal transport and absorption of two P-glycoprotein substrates in rats. | Archives of pharmacal research 20110701 |
N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. | Journal of medicinal chemistry 20110623 |
Anticancer properties of an important drug lead podophyllotoxin can be efficiently mimicked by diverse heterocyclic scaffolds accessible via one-step synthesis. | Journal of medicinal chemistry 20110623 |
Liposome-encapsulated doxorubicin reverses drug resistance by inhibiting P-glycoprotein in human cancer cells. | Molecular pharmaceutics 20110606 |
Prolonged fever: an atypical presentation of Behcet's disease. | Rheumatology international 20110601 |
Panniculitis: another clinical expression of gout. | Rheumatology international 20110601 |
Molecular modelling and competition binding study of Br-noscapine and colchicine provide insight into noscapinoid-tubulin binding site. | Journal of molecular graphics & modelling 20110601 |
Imidazolone-amide bridges and their effects on tubulin polymerization in cis-locked vinylogous combretastatin-A4 analogues: synthesis and biological evaluation. | Bioorganic & medicinal chemistry 20110601 |
Exploration of acridine scaffold as a potentially interesting scaffold for discovering novel multi-target VEGFR-2 and Src kinase inhibitors. | Bioorganic & medicinal chemistry 20110601 |
Safety of subcutaneous microinjections (mesotherapy) in musicians. | Medical problems of performing artists 20110601 |
UA62784 Is a cytotoxic inhibitor of microtubules, not CENP-E. | Chemistry & biology 20110527 |
Nanocavity effect on photophysical properties of colchicine: a proof by circular dichroism study and picosecond time-resolved analysis in various reverse micellar assemblies. | The journal of physical chemistry. B 20110526 |
Molecular data and ploidal levels indicate several putative allopolyploidization events in the genus Potentilla (Rosaceae). | PLoS currents 20110516 |
Synthesis and biological evaluation of 2,4,5-substituted pyrimidines as a new class of tubulin polymerization inhibitors. | Journal of medicinal chemistry 20110512 |
Dynamic imaging of axonal transport in living retinal ganglion cells in vitro. | Investigative ophthalmology & visual science 20110509 |
Synthesis and antitumor evaluation of nitrovinyl biphenyls: anticancer agents based on allocolchicines. | ChemMedChem 20110502 |
Epidermolysis bullosa acquisita: a retrospective clinical analysis of 30 cases. | Acta dermato-venereologica 20110501 |
Rational design, synthesis and biological evaluations of amino-noscapine: a high affinity tubulin-binding noscapinoid. | Journal of computer-aided molecular design 20110501 |
Managing your patient with gout: a review of treatment options. | Postgraduate medicine 20110501 |
Peyronie's disease: review of nonsurgical treatment options. | The Urologic clinics of North America 20110501 |
Vitamin D status in patients with Behcet's Disease. | Clinics (Sao Paulo, Brazil) 20110501 |
Synthesis, biological evaluation, and molecular docking studies of resveratrol derivatives possessing chalcone moiety as potential antitubulin agents. | Bioorganic & medicinal chemistry 20110415 |
Actin filament-organized local cortical endoplasmic reticulum aggregations in developing stomatal complexes of grasses. | Protoplasma 20110401 |
Long-term therapy for chronic gout results in clinically important improvements in the health-related quality of life: short form-36 is responsive to change in chronic gout. | Rheumatology (Oxford, England) 20110401 |
Transcriptional activation of the anchoring protein SAP97 by heat shock factor (HSF)-1 stabilizes K(v) 1.5 channels in HL-1 cells. | British journal of pharmacology 20110401 |
Role of melanocortin receptors in the regulation of gouty inflammation. | Current rheumatology reports 20110401 |
EULAR recommendations for calcium pyrophosphate deposition. Part II: management. | Annals of the rheumatic diseases 20110401 |
Isolated optic neuropathy in a case of Behçet's disease. | International ophthalmology 20110401 |
Apoptotic microtubule network organization and maintenance depend on high cellular ATP levels and energized mitochondria. | Apoptosis : an international journal on programmed cell death 20110401 |
Current status and new developments in Peyronie's disease: medical, minimally invasive and surgical treatment options. | Expert opinion on pharmacotherapy 20110401 |
[Retroperitoneal fibrosis associated with chronic use of ergotamine: report of one case]. | Revista medica de Chile 20110401 |
[Hereditary periodical fever syndromes]. | Ugeskrift for laeger 20110328 |
Antitumor agents. 284. New desmosdumotin B analogues with bicyclic B-ring as cytotoxic and antitubulin agents. | Journal of medicinal chemistry 20110310 |
Loss of mitochondrial complex I activity potentiates dopamine neuron death induced by microtubule dysfunction in a Parkinson's disease model. | The Journal of cell biology 20110307 |
Immunodetection of retinoblastoma-related protein and its phosphorylated form in interphase and mitotic alfalfa cells. | Journal of experimental botany 20110301 |
Docking, synthesis, and in vitro evaluation of antimitotic estrone analogs. | Chemical biology & drug design 20110301 |
Colchicine modulates oxidative stress in serum and leucocytes from remission patients with Family Mediterranean Fever through regulation of Ca²+ release and the antioxidant system. | The Journal of membrane biology 20110301 |
[Linear IgA bullous dermatosis: a review]. | Annales de dermatologie et de venereologie 20110301 |
[Epidermolysis bullosa acquisita: literature review]. | Annales de dermatologie et de venereologie 20110301 |
Thiocolchicoside-induced liver injury. | Clinics (Sao Paulo, Brazil) 20110301 |
Sweet's syndrome associated with Mycobacterium tuberculosis and cervical cancer: a case report. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20110301 |
Control of MCT1 function in cerebrovascular endothelial cells by intracellular pH. | Brain research 20110227 |
Clinical practice. Gout. | The New England journal of medicine 20110203 |
High frequency production of rapeseed transgenic plants via combination of microprojectile bombardment and secondary embryogenesis of microspore-derived embryos. | Molecular biology reports 20110201 |
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model. | Drug metabolism and disposition: the biological fate of chemicals 20110201 |
Educational paper: Primary immunodeficiencies in children: a diagnostic challenge. | European journal of pediatrics 20110201 |
Simultaneous HPLC determination of thiocolchicoside and glafenine as well as thiocolchicoside and floctafenine in their combined dosage forms. | Journal of chromatographic science 20110201 |
Prevalence of contraindications and prescription of pharmacologic therapies for gout. | The American journal of medicine 20110201 |
Anticolchicine cytotoxicity enhanced by Dan Gua-Fang, a Chinese herb prescription in ECV304 in mediums. | Chinese journal of integrative medicine 20110201 |
Statistical optimization of process variables for the production of an anticancer drug (colchicine derivatives) through fermentation: at scale-up level. | New biotechnology 20110131 |
Distribution of 5-HT2A receptor immunoreactivity in the rat amygdaloid complex and colocalization with γ-aminobutyric acid. | Brain research 20110125 |
Synthesis and pharmacological evaluation of N-(3-(1H-indol-4-yl)-5-(2-methoxyisonicotinoyl)phenyl)methanesulfonamide (LP-261), a potent antimitotic agent. | Journal of medicinal chemistry 20110113 |
Gout. Aspects of management. | BMJ (Clinical research ed.) 20110111 |
Investigation of ABCB1 gene polymorphism with colchicine response in Behçet's disease. | Genetics and molecular research : GMR 20110104 |
The involvement of microtubules and actin filaments in the intracellular transport of non-viral gene delivery system. | Journal of drug targeting 20110101 |
The initial segment of the rat epididymis is able to uptake immature germ cells shed by testicular damage. | Cells, tissues, organs 20110101 |
Tubulin photoaffinity labeling study with a plinabulin chemical probe possessing a biotin tag at the oxazole. | Bioorganic & medicinal chemistry 20110101 |
Colchicine-induced rhabdomyolysis in a heart/lung transplant patient with concurrent use of cyclosporin, pravastatin, and azithromycin. | Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20110101 |
Periodic Fever syndromes. | Pediatric annals 20110101 |
Treatment of gout. | Internal medicine journal 20110101 |
Familial Mediterranean fever presenting with pulmonary embolism. | Connecticut medicine 20110101 |
[Effect of colchicine and Triton X-100 on expression of the enzyme-encoding genes in nongerminating seeds of sugarbeet (Beta vulgaris L.)]. | Genetika 20110101 |
Enhancement of artemisinin content in tetraploid Artemisia annua plants by modulating the expression of genes in artemisinin biosynthetic pathway. | Biotechnology and applied biochemistry 20110101 |
Modulation of P-glycoprotein-mediated anticancer drug accumulation, cytotoxicity, and ATPase activity by flavonoid interactions. | Nutrition and cancer 20110101 |
Efficacy of anti-interleukin-1 receptor antagonist anakinra (Kineret®) in a case of refractory Sweet's syndrome. | Dermatology (Basel, Switzerland) 20110101 |
Beneficial effects of colchicine on 17alpha-ethynylestradiol-induced cholestasis in rats. | Arzneimittel-Forschung 20110101 |
Gout. | BMJ clinical evidence 20110101 |
Frosted branch angiitis, neuroretinitis as initial ocular manifestation in Behçet disease. | Indian journal of ophthalmology 20110101 |
Tophaceous gout and renal insufficiency: a new solution for an old therapeutic dilemma. | Case reports in medicine 20110101 |
A double-blind randomized controlled trial appraising the symptom-modifying effects of colchicine on osteoarthritis of the knee. | Clinical and experimental rheumatology 20110101 |
Induction and flow cytometry identification of tetraploids from seed-derived explants through colchicine treatments in Catharanthus roseus (L.) G. Don. | Journal of biomedicine & biotechnology 20110101 |
Specific microtubule-depolymerizing agents augment efficacy of dendritic cell-based cancer vaccines. | Journal of biomedical science 20110101 |
Amicrobial pustulosis of the folds revealing asymptomatic autoimmune thyroiditis. | European journal of dermatology : EJD 20110101 |
Decorin and colchicine as potential treatments for post-haemorrhagic ventricular dilatation in a neonatal rat model. | Neonatology 20110101 |
Rapid mass movement of chloroplasts during segment formation of the calcifying siphonalean green alga, Halimeda macroloba. | PloS one 20110101 |
Improvement of colchicine oral bioavailability by incorporating eugenol in the nanoemulsion as an oil excipient and enhancer. | International journal of nanomedicine 20110101 |
Recurrent pericardial effusion after cardiac surgery: the use of colchicine after recalcitrant conventional therapy. | Journal of cardiothoracic surgery 20110101 |
Association between ABCB1 (MDR1) gene 3435 C>T polymorphism and colchicine unresponsiveness of FMF patients. | Renal failure 20110101 |
Unpolarized release of vaccinia virus and HIV antigen by colchicine treatment enhances intranasal HIV antigen expression and mucosal humoral responses. | PloS one 20110101 |
Substance P induces rapid and transient membrane blebbing in U373MG cells in a p21-activated kinase-dependent manner. | PloS one 20110101 |
Phosphorylation of voltage-dependent anion channel by serine/threonine kinases governs its interaction with tubulin. | PloS one 20110101 |
A polymeric colchicinoid prodrug with reduced toxicity and improved efficacy for vascular disruption in cancer therapy. | International journal of nanomedicine 20110101 |
Simultaneous estimation of etoricoxib and thiocolchicoside by RP-HPLC method in combined dosage forms. | Acta poloniae pharmaceutica 20110101 |
Recurrent pericarditis after chemotherapy for acute myeloid leukemia: a case report and a modern approach to chemotherapy-induced pericarditis. | Cardiology 20110101 |
Effectiveness of lumbar zygapophysial joint blockage for low back pain. | Turkish neurosurgery 20110101 |
Ursodeoxycholic acid is conjugated with taurine to promote secretin-stimulated biliary hydrocholeresis in the normal rat. | PloS one 20110101 |
A case of occupational gout. | Irish medical journal 20110101 |
Free tubulin modulates mitochondrial membrane potential in cancer cells. | Cancer research 20101215 |
Intramolecular Nicholas reactions in the synthesis of dibenzocycloheptanes. Synthesis of allocolchicine NSC 51046 and analogues and the formal synthesis of (-)-allocolchicine. | The Journal of organic chemistry 20101203 |
Clinical images: bead-like gouty tophi in the hand and foot. | Arthritis and rheumatism 20101201 |
Effects of exposure to a time-varying 1.5 T magnetic field on the neurotransmitter-activated increase in intracellular Ca(2+) in relation to actin fiber and mitochondrial functions in bovine adrenal chromaffin cells. | Biochimica et biophysica acta 20101201 |
A predictive ligand-based Bayesian model for human drug-induced liver injury. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
Synthesis, molecular modeling and biological evaluation of guanidine derivatives as novel antitubulin agents. | Bioorganic & medicinal chemistry 20101201 |
Crystal arthropathies: recognizing and treating 'the gouch'. | Primary care 20101201 |
Colchicine must be stopped before imaging with [18F]-methylcholine PET/CT. | Nuclear medicine communications 20101201 |
[Treatment of hyperuricemia and gout based on the guideline for the management of hyperuricemia and gout]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20101201 |
Fatigue in colchicine myopathy: a study of transcranial magnetic stimulation. | Journal of the Chinese Medical Association : JCMA 20101201 |
Managing gout: how is it different in patients with chronic kidney disease? | Cleveland Clinic journal of medicine 20101201 |
Synthesis and discovery of water-soluble microtubule targeting agents that bind to the colchicine site on tubulin and circumvent Pgp mediated resistance. | Journal of medicinal chemistry 20101125 |
A late and difficult diagnosis of ochronosis. | Journal of medicine and life 20101115 |
Gout in young migrant Filipino women in Israel: a changing epidemiology. Case reports and review of the literature. | Rheumatology international 20101101 |
A case of the Behcet's disease diagnosed by the panniculits after mesotherapy. | Rheumatology international 20101101 |
Methotrexate in patients with primary biliary cirrhosis who respond incompletely to treatment with ursodeoxycholic acid. | Digestive diseases and sciences 20101101 |
Synthesis and cytotoxicity evaluation of novel 1,4-disubstituted 1,2,3-triazoles via CuI catalysed 1,3-dipolar cycloaddition. | European journal of medicinal chemistry 20101101 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
Thiocolchicoside exhibits anticancer effects through downregulation of NF-κB pathway and its regulated gene products linked to inflammation and cancer. | Cancer prevention research (Philadelphia, Pa.) 20101101 |
Synthesis and cellular pharmacology studies of a series of 2-amino-3-aroyl-4-substituted thiophene derivatives. | Medicinal chemistry (Shariqah (United Arab Emirates)) 20101101 |
The current state of care in gout: Addressing the need for better understanding of an ancient disease. | Journal of the American Academy of Nurse Practitioners 20101101 |
Disruption of microtubules sensitizes the DNA damage-induced apoptosis through inhibiting nuclear factor κB (NF-κB) DNA-binding activity. | Journal of Korean medical science 20101101 |
Etoposide; colchicine; mitomycin C and cyclophosphamide tested in the in vitro mammalian cell micronucleus test (MNvit) in Chinese hamster lung (CHL) cells at Covance laboratories; Harrogate UK in support of OECD draft Test Guideline 487. | Mutation research 20101029 |
Mitomycin C, 5-fluoruracil, colchicine and etoposide tested in the in vitro mammalian cell micronucleus test (MNvit) in the human lymphoblastoid cell line TK6 at Novartis in support of OECD draft Test Guideline 487. | Mutation research 20101029 |
Comparison of different cytotoxicity measures for the in vitro micronucleus test (MNVit) in L5178Y tk(+/-) cells: Summary of 4 compounds (Mitomycin C, Cyclophosphamide, Colchicine and Diethylstilboestrol) with clastogenic and aneugenic mode of action. | Mutation research 20101029 |
5-Fluorouracil, colchicine, benzo[a]pyrene and cytosine arabinoside tested in the in vitro mammalian cell micronucleus test (MNvit) in Chinese hamster V79 cells at Covance Laboratories, Harrogate, UK in support of OECD draft Test Guideline 487. | Mutation research 20101029 |
2-Aminoanthracene, 5-fluorouracil, colchicine, benzo[a]pyrene, cadmium chloride and cytosine arabinoside tested in the in vitro mammalian cell micronucleus test (MNvit) in Chinese hamster ovary (CHO) cells at Covance Laboratories, Harrogate UK in support of OECD draft Test Guideline 487. | Mutation research 20101029 |
Discovery of novel 2-aryl-4-benzoyl-imidazoles targeting the colchicines binding site in tubulin as potential anticancer agents. | Journal of medicinal chemistry 20101028 |
[Ciclosporin-associated cerebral tumor-like location of Behçet's disease]. | Revue neurologique 20101001 |
Quantitation of 'autophagic flux' in mature skeletal muscle. | Autophagy 20101001 |
Competitive mass spectrometry binding assay for characterization of three binding sites of tubulin. | Journal of mass spectrometry : JMS 20101001 |
Phosphoinositide 3-kinase/protein kinase B signaling pathway is involved in estradiol 17β-D-glucuronide-induced cholestasis: complementarity with classical protein kinase C. | Hepatology (Baltimore, Md.) 20101001 |
Treatment of morphea or localized scleroderma: review of the literature. | Journal of drugs in dermatology : JDD 20101001 |
Multiple organ failure after an overdose of less than 0.4 mg/kg of colchicine: role of coingestants and drugs during intensive care management. | Clinical toxicology (Philadelphia, Pa.) 20101001 |
Studies on combinations of platinum with paclitaxel and colchicine in ovarian cancer cell lines. | Anticancer research 20101001 |
Scleredema treated with broad-band ultraviolet A phototherapy plus colchicine. | Photodermatology, photoimmunology & photomedicine 20101001 |
Modulation of the cyclooxygenase pathway via inhibition of nitric oxide production contributes to the anti-inflammatory activity of kaempferol. | European journal of pharmacology 20100910 |
Non-steroid agents for idiopathic pulmonary fibrosis. | The Cochrane database of systematic reviews 20100908 |
RhoA and DIAPH1 mediate adrenocorticotropin-stimulated cortisol biosynthesis by regulating mitochondrial trafficking. | Endocrinology 20100901 |
Primary endothelial damage is the mechanism of cardiotoxicity of tubulin-binding drugs. | Toxicological sciences : an official journal of the Society of Toxicology 20100901 |
Development of a novel tumor-targeted vascular disrupting agent activated by membrane-type matrix metalloproteinases. | Cancer research 20100901 |
Glycopeptide dendrimer colchicine conjugates targeting cancer cells. | Bioorganic & medicinal chemistry 20100901 |
Fatigue as the only clinical manifestation of colchicine induced myopathy. | Acta neurologica Taiwanica 20100901 |
Pharmacologic management of chronic constipation. | Gastroenterology clinics of North America 20100901 |
Rhabdomyolysis induced by co-administration of fluvastatin and colchicine. | Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 20100901 |
Oral colchicine (Colcrys): in the treatment and prophylaxis of gout. | Drugs 20100820 |
Chelation of intracellular iron enhances endothelial barrier function: a role for vitamin C? | Archives of biochemistry and biophysics 20100815 |
Origins of endomorphin-2 immunopositive fibers and terminals in the spinal dorsal horn of the rat. | Neuroscience 20100811 |
Pulmonary artery aneurysms in Behçet's disease. | Rheumatology international 20100801 |
Colchicine-induced apoptosis was prevented by glycogen synthase kinase-3 inhibitors in PC12 cells. | Cellular and molecular neurobiology 20100801 |
Synthesis and tubulin-binding properties of new allocolchicinoids. | Bioorganic chemistry 20100801 |
Management of pericardial diseases during pregnancy. | Journal of cardiovascular medicine (Hagerstown, Md.) 20100801 |
Synthesis, antiproliferative activity and inhibition of tubulin polymerization by 1,5- and 1,8-disubstituted 10H-anthracen-9-ones bearing a 10-benzylidene or 10-(2-oxo-2-phenylethylidene) moiety. | European journal of medicinal chemistry 20100801 |
Microtubule-binding natural products for cancer therapy. | Planta medica 20100801 |
Colchicine myopathy and neuromyopathy: two cases with different characteristics. | Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20100801 |
Protective effect of naringin, a citrus flavonoid, against colchicine-induced cognitive dysfunction and oxidative damage in rats. | Journal of medicinal food 20100801 |
Gout of the temporomandibular joint: a review of the literature. | Journal of the American Dental Association (1939) 20100801 |
Antitumor agents 273. Design and synthesis of N-alkyl-thiocolchicinoids as potential antitumor agents. | Bioorganic & medicinal chemistry letters 20100715 |
Clinical features and functional significance of the P369S/R408Q variant in pyrin, the familial Mediterranean fever protein. | Annals of the rheumatic diseases 20100701 |
Response rates to medical treatments and long-term clinical outcomes of nonsurgical patients with intestinal Behçet disease. | Journal of clinical gastroenterology 20100701 |
HMBA depolymerizes microtubules, activates mitotic checkpoints and induces mitotic block in MCF-7 cells by binding at the colchicine site in tubulin. | Biochemical pharmacology 20100701 |
Structural determinants of resveratrol for cell proliferation inhibition potency: experimental and docking studies of new analogs. | European journal of medicinal chemistry 20100701 |
Synthesis, antiproliferative activity evaluation and structure-activity relationships of novel aromatic urea and amide analogues of N-phenyl-N'-(2-chloroethyl)ureas. | European journal of medicinal chemistry 20100701 |
Induction of the arginine vasopressin-enhanced green fluorescent protein fusion transgene in the rat locus coeruleus. | Stress (Amsterdam, Netherlands) 20100701 |
A comparative study with colchicine on glutathione reductase. | The protein journal 20100701 |
Five molecules we would take to a remote island. | Chemistry & biology 20100625 |
Synthesis, molecular modeling and biological evaluation of dithiocarbamates as novel antitubulin agents. | Bioorganic & medicinal chemistry 20100615 |
Microtubular stability affects cardiomyocyte glycolysis by HIF-1alpha expression and endonuclear aggregation during early stages of hypoxia. | American journal of physiology. Heart and circulatory physiology 20100601 |
Differential regulation of cardiac glucose and fatty acid uptake by endosomal pH and actin filaments. | American journal of physiology. Cell physiology 20100601 |
Albumin uptake in OK cells exposed to rotenone: a model for studying the effects of mitochondrial dysfunction on endocytosis in the proximal tubule? | Nephron. Physiology 20100601 |
Comparison of colchicine versus prednisolone in recurrent aphthous stomatitis: A double-blind randomized clinical trial. | Clinical and investigative medicine. Medecine clinique et experimentale 20100601 |
Cloning and heterologous expression of the ovine (Ovis aries) P-glycoprotein (Mdr1) in Madin-Darby canine kidney (MDCK) cells. | Journal of veterinary pharmacology and therapeutics 20100601 |
Colchicine poisoning: the dark side of an ancient drug. | Clinical toxicology (Philadelphia, Pa.) 20100601 |
Protracted febrile myalgia in two children with familial Mediterranean fever. | Pediatrics international : official journal of the Japan Pediatric Society 20100601 |
Phenylcinnamides as novel antimitotic agents. | Journal of medicinal chemistry 20100527 |
Synthesis and antitumor activity of 1,5-disubstituted 1,2,4-triazoles as cis-restricted combretastatin analogues. | Journal of medicinal chemistry 20100527 |
Electrophysiological and morphological characteristics and synaptic connectivity of tyrosine hydroxylase-expressing neurons in adult mouse striatum. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100519 |
Methotrexate for primary biliary cirrhosis. | The Cochrane database of systematic reviews 20100512 |
Dramatic response to IL1-RA treatment in longstanding multidrug resistant Schnitzler's syndrome: a case report and literature review. | Clinical rheumatology 20100501 |
Blockage of mitosis in maize root tips using colchicine-alternatives. | Protoplasma 20100501 |
Inhibitor of kappaB kinase beta regulates redox homeostasis by controlling the constitutive levels of glutathione. | Molecular pharmacology 20100501 |
Chemotherapeutic agents targeting the tubulin cytoskeleton modify LPS-induced cytokine secretion by dendritic cells and increase antigen presentation. | Journal of immunotherapy (Hagerstown, Md. : 1997) 20100501 |
Reactivation of anti-human alpha-enolase antibody-positive Behçet's disease by carbon dioxide laser treatment. | Acta dermato-venereologica 20100501 |
N-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)arylamide as a new scaffold that provides rapid access to antimicrotubule agents: synthesis and evaluation of antiproliferative activity against select cancer cell lines. | Journal of medicinal chemistry 20100422 |
Eruptive neutrophilic xanthomas. | Dermatology online journal 20100415 |
Synthesis, antitubulin, and antiproliferative SAR of analogues of 2-methoxyestradiol-3,17-O,O-bis-sulfamate. | Journal of medicinal chemistry 20100408 |
Characterization of the colchicine binding site on avian tubulin isotype betaVI. | Biochemistry 20100406 |
Embryonic retinal cells and support to mature retinal neurons. | Investigative ophthalmology & visual science 20100401 |
Influenza virus B-associated hemophagocytic syndrome and recurrent pericarditis in a patient with systemic lupus erythematosus. | Modern rheumatology 20100401 |
High versus low dosing of oral colchicine for early acute gout flare: Twenty-four-hour outcome of the first multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-comparison colchicine study. | Arthritis and rheumatism 20100401 |
[Successful treatment of a case of steroid-dependent neuro-Sweet disease with dapsone]. | Rinsho shinkeigaku = Clinical neurology 20100401 |
New agents for the treatment of gout and hyperuricemia: febuxostat, puricase, and beyond. | Current rheumatology reports 20100401 |
Microplate spectrophotometry for high-throughput screening of cytotoxic molecules. | Cell proliferation 20100401 |
Perplexing pyretic polyarthritis. | Journal of the Mississippi State Medical Association 20100401 |
Expression of papillomavirus L1 proteins regulated by authentic gene codon usage is favoured in G2/M-like cells in differentiating keratinocytes. | Virology 20100330 |
Discovery and development of natural product-derived chemotherapeutic agents based on a medicinal chemistry approach. | Journal of natural products 20100326 |
[Chondrocalcinosis and calcium pyrophosphate (CPP) crystal deposition disease in 2010]. | Revue medicale suisse 20100317 |
Evaluation of transcriptional activity of caspase-3 gene as a marker of acute neurotoxicity in rat cerebellar granular cells. | Toxicology in vitro : an international journal published in association with BIBRA 20100301 |
Progress in the pharmacotherapy of gout. | Current opinion in rheumatology 20100301 |
Diagnosing and treating gout: a review to aid primary care physicians. | Postgraduate medicine 20100301 |
MAP65 in tubulin/colchicine paracrystals of Vigna sinensis root cells: possible role in the assembly and stabilization of atypical tubulin polymers. | Cytoskeleton (Hoboken, N.J.) 20100301 |
[Pseudotumor cerebri secondary to Behçet disease. Report of one case]. | Revista medica de Chile 20100301 |
A case of aseptic pleuropericarditis in a patient with chronic plaque psoriasis under methotrexate therapy. | Dermatology online journal 20100215 |
[A sciatica occurring in Behçet's disease]. | La Revue de medecine interne 20100201 |
Ultrasonography shows disappearance of monosodium urate crystal deposition on hyaline cartilage after sustained normouricemia is achieved. | Rheumatology international 20100201 |
Colchicine treatment in autosomal dominant polycystic kidney disease: many points in common. | Medical hypotheses 20100201 |
Recovery of tubulin functions after freeze-drying in the presence of trehalose. | Analytical biochemistry 20100201 |
Derivatives of thiocolchicine and its applications to CEM cells treatment using 19F magnetic resonance ex vivo. | Bioorganic chemistry 20100201 |
Effects of photoperiod on kisspeptin neuronal populations of the ewe diencephalon in connection with reproductive function. | Journal of neuroendocrinology 20100201 |
Isolation and anti-inflammatory activity of colchicinoids from Gloriosa superba seeds. | Pharmaceutical biology 20100201 |
Design and pharmacophore modeling of biaryl methyl eugenol analogs as breast cancer invasion inhibitors. | Bioorganic & medicinal chemistry 20100115 |
A facile synthesis of dibenzopyrroloazepinones as tetracyclic allocolchicinoids--an unusual 1,2-phenyl shift. | Chemical communications (Cambridge, England) 20100114 |
Cellular processes essential for African swine fever virus to infect and replicate in primary macrophages. | Veterinary microbiology 20100106 |
The modern management of gout. | Rheumatology (Oxford, England) 20100101 |
Synthesis and biological evaluation of novel thiocolchicine-podophyllotoxin conjugates. | European journal of medicinal chemistry 20100101 |
Prognosis of Behcet's syndrome among men with mucocutaneous involvement at disease onset: long-term outcome of patients enrolled in a controlled trial. | Rheumatology (Oxford, England) 20100101 |
Non-opsonic phagocytosis of homologous non-toxigenic and toxigenic Corynebacterium diphtheriae strains by human U-937 macrophages. | Microbiology and immunology 20100101 |
Intact cytoskeleton is required for small G protein dependent activation of the epithelial Na+ channel. | PloS one 20100101 |
[Fever and back pain--a case report of spinal gout]. | Deutsche medizinische Wochenschrift (1946) 20100101 |
The dynamics of chronic gout treatment: medication gaps and return to therapy. | The American journal of medicine 20100101 |
Infliximab for the treatment of refractory Adamantiades-Behçet disease with articular, intestinal, cerebral and ocular involvement. | Dermatology (Basel, Switzerland) 20100101 |
[A rare cause of cyanosis: Sulphaemoglobinaemia related to thiocolchicoside (Miorel)]. | Revue des maladies respiratoires 20100101 |
Object exploration and reactions to spatial and nonspatial changes in dentate gyrus lesioned rats. | Georgian medical news 20100101 |
Induction of autophagy by cystatin C: a mechanism that protects murine primary cortical neurons and neuronal cell lines. | PloS one 20100101 |
Immunomodulatory drugs regulate HMGB1 release from activated human monocytes. | Molecular medicine (Cambridge, Mass.) 20100101 |
Comparative effects of microtubules disruption on glucocorticoid receptor functions in proliferating and quiescent cells. | International journal of toxicology 20100101 |
A novel synthetic analog of 5, 8-disubstituted quinazolines blocks mitosis and induces apoptosis of tumor cells by inhibiting microtubule polymerization. | PloS one 20100101 |
Fluorescence spectroscopic methods to analyze drug-tubulin interactions. | Methods in cell biology 20100101 |
[Endocytosis of cholinoreceptors in the mechanism of depression of cholinosensitivity in Helix lucorum neurons in a cellular model of habituation]. | Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20100101 |
[Fatal interaction between colchicine and clarythromycin]. | Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20100101 |
On the chiroptical behavior of conjugated multichromophoric compounds of a new pseudoaromatic class: bicolchicides and biisocolchicides. | PloS one 20100101 |
Quantitative analysis of the effect of tubulin isotype expression on sensitivity of cancer cell lines to a set of novel colchicine derivatives. | Molecular cancer 20100101 |
High-performance thin-layer chromatographic determination of etoricoxib and thiocolchicoside in combined tablet dosage form. | Journal of AOAC International 20100101 |
The organization of CRF neuronal pathways in toads: Evidence that retinal afferents do not contribute significantly to tectal CRF content. | Brain, behavior and evolution 20100101 |
[About possible specialization of different compartments of a motoneuron axon for synthesis of specific proteins]. | Biofizika 20100101 |
Effects of inhibition of interleukin-6 signalling on insulin sensitivity and lipoprotein (a) levels in human subjects with rheumatoid diseases. | PloS one 20100101 |
Systemic sclerosis in a patient with pityriasis rubra pilaris. | The Pan African medical journal 20100101 |
Effects of colchicine or demecolcine on cytoplasmic protrusions and assisted enucleation of golden hamster oocytes. | Cell biology international 20091201 |
Secretagogue stimulation enhances NBCe1 (electrogenic Na(+)/HCO(3)(-) cotransporter) surface expression in murine colonic crypts. | American journal of physiology. Gastrointestinal and liver physiology 20091201 |
Production of tetraploid plants of non apomictic citrus genotypes. | Plant cell reports 20091201 |
A review of the effectiveness of antimitotic drug injections for hypertrophic scars and keloids. | Annals of plastic surgery 20091201 |
Colchicine for the primary and secondary prevention of pericarditis: an update. | The Annals of pharmacotherapy 20091201 |
Hydropathic analysis and biological evaluation of stilbene derivatives as colchicine site microtubule inhibitors with anti-leukemic activity. | Journal of enzyme inhibition and medicinal chemistry 20091201 |
A survey on the management of gout in Malaysia. | International journal of rheumatic diseases 20091201 |
Colchicine and other drugs for gout. | The Medical letter on drugs and therapeutics 20091130 |
An integrative approach for the isolation, screening and analysis of antitumor agents by liquid chromatography combined with mass spectrometry. | Analytica chimica acta 20091123 |
Combretastatin-like chalcones as inhibitors of microtubule polymerisation. Part 2: Structure-based discovery of alpha-aryl chalcones. | Bioorganic & medicinal chemistry 20091115 |
Interference with endothelial cell function by JG-03-14, an agent that binds to the colchicine site on microtubules. | Biochemical pharmacology 20091101 |
[Frosted-branch angiitis revealing Behçet's disease]. | Journal francais d'ophtalmologie 20091101 |
Treatment of recurrent aphthous stomatitis with clofazimine. | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20091101 |
Synthesis, biological evaluation of 1,1-diarylethylenes as a novel class of antimitotic agents. | ChemMedChem 20091101 |
Hydroxychloroquine and colchicine induced myopathy. | The Journal of rheumatology 20091101 |
Treatment failure gout. | Medicine and health, Rhode Island 20091101 |
Phenotypic diversity and expression of GABAergic inhibitory interneurons during postnatal development in lumbar spinal cord of glutamic acid decarboxylase 67-green fluorescent protein mice. | Neuroscience 20091020 |
Regional differences in capillary density, perfusion rate, and P-glycoprotein activity: a quantitative analysis of regional drug exposure in the brain. | Biochemical pharmacology 20091015 |
Comparison of the spatial distribution of seven types of neuroendocrine neurons in the rat paraventricular nucleus: toward a global 3D model. | The Journal of comparative neurology 20091010 |
Correlation between anti-fibrotic effect of baicalin and serum cytokines in rat hepatic fibrosis. | World journal of gastroenterology 20091007 |
Hyperalgesia, synovitis and multiple biomarkers of inflammation are suppressed by interleukin 1 inhibition in a novel animal model of gouty arthritis. | Annals of the rheumatic diseases 20091001 |
Potentially fatal interaction between colchicine and disulfiram. | Progress in neuro-psychopharmacology & biological psychiatry 20091001 |
Multiple efflux pumps are involved in the transepithelial transport of colchicine: combined effect of p-glycoprotein and multidrug resistance-associated protein 2 leads to decreased intestinal absorption throughout the entire small intestine. | Drug metabolism and disposition: the biological fate of chemicals 20091001 |
Role of sarcoplasmic reticulum in mitochondrial permeability transition and cardiomyocyte death during reperfusion. | American journal of physiology. Heart and circulatory physiology 20091001 |
Application of the McMurry coupling reaction in the synthesis of tri- and tetra-arylethylene analogues as potential cancer chemotherapeutic agents. | Bioorganic & medicinal chemistry 20091001 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. | Nature chemical biology 20091001 |
Design, synthesis and structure-activity relationship of 2-(3',4',5'-trimethoxybenzoyl)-benzo[b]furan derivatives as a novel class of inhibitors of tubulin polymerization. | Bioorganic & medicinal chemistry 20091001 |
Interaction of phenylbutazone and colchicine in binding to serum albumin in rheumatoid therapy: 1H NMR study. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090915 |
Crohn's disease and secondary amyloidosis: early complication? A case report and review of the literature. | Journal of renal care 20090901 |
Short term treatment with clarithromycin resulting in colchicine-induced rhabdomyolysis. | Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20090901 |
Synthesis and evaluation of 3-aroylindoles as anticancer agents: metabolite approach. | Journal of medicinal chemistry 20090813 |
Opportunities for improving medication use and monitoring in gout. | Annals of the rheumatic diseases 20090801 |
M694V mutation may have a role in susceptibility to ankylosing spondylitis. | Rheumatology international 20090801 |
Lichen sclerosus of the oral mucosa: clinicopathological features of six cases. | International journal of oral and maxillofacial surgery 20090801 |
The role of kinesin, dynein and microtubules in pancreatic secretion. | Cellular and molecular life sciences : CMLS 20090801 |
Design, synthesis and identification of novel colchicine-derived immunosuppressant. | Bioorganic & medicinal chemistry letters 20090801 |
Adenosine regulation of microtubule dynamics in cardiac hypertrophy. | American journal of physiology. Heart and circulatory physiology 20090801 |
Acylphloroglucinol, biyouyanagiol, biyouyanagin B, and related spiro-lactones from Hypericum chinense. | Journal of natural products 20090801 |
Individualized therapy for pericarditis. | Expert review of cardiovascular therapy 20090801 |
Isocombretastatins a versus combretastatins a: the forgotten isoCA-4 isomer as a highly promising cytotoxic and antitubulin agent. | Journal of medicinal chemistry 20090723 |
Colchicine attenuates inflammatory cell infiltration and extracellular matrix accumulation in diabetic nephropathy. | American journal of physiology. Renal physiology 20090701 |
Discovery of 4-anilino-N-methylthieno[3,2-d]pyrimidines and 4-anilino-N-methylthieno[2,3-d]pyrimidines as potent apoptosis inducers. | Bioorganic & medicinal chemistry letters 20090701 |
Gout Study Group: update on hyperuricemia and gout. | Joint, bone, spine : revue du rhumatisme 20090701 |
The efficacy of topical thiocolchicoside (Muscoril) in the treatment of acute cervical myofascial pain syndrome: a single-blind, randomized, prospective, phase IV clinical study. | Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology 20090701 |
Changes in the reciprocal position of the first polar body and oocyte chromosome set in golden hamsters. | Bioscience reports 20090625 |
Peptide 19 in the rat superior cervical ganglion. | Neuroscience 20090616 |
Cytoskeletal reorganisation, 1alpha,25-dihydroxy vitamin D3 and human MG63 osteoblast maturation. | Molecular and cellular endocrinology 20090616 |
Insecticidal heterolignans--tubuline polymerization inhibitors with activity against chewing pests. | Bioorganic & medicinal chemistry 20090615 |
Colchicine update: 2008. | Seminars in arthritis and rheumatism 20090601 |
A diaryl sulfide, sulfoxide, and sulfone bearing structural similarities to combretastatin A-4. | European journal of medicinal chemistry 20090601 |
Use of centromeric and telomeric DNA probes in in situ hybridization for differentiation of micronuclei induced by lomefloxacin. | Environmental and molecular mutagenesis 20090601 |
Differential requirement for MEK/ERK and SMAD signaling in PAI-1 and CTGF expression in response to microtubule disruption. | Cellular signalling 20090601 |
Dopamine released by dendritic cells polarizes Th2 differentiation. | International immunology 20090601 |
Concurrent protective and destructive signaling of JNK2 in neuroblastoma cells. | Cellular signalling 20090601 |
Novel carbazole and acyl-indole antimitotics. | Bioorganic & medicinal chemistry letters 20090601 |
Discovery of N-aryl-9-oxo-9H-fluorene-1-carboxamides as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 1. Structure-activity relationships of the carboxamide group. | Bioorganic & medicinal chemistry letters 20090601 |
Gout--what are the treatment options? | Expert opinion on pharmacotherapy 20090601 |
Microtubule depolymerization modifies the incorporation of fatty acids into glycerolipids. | Medical science monitor : international medical journal of experimental and clinical research 20090601 |
[Research of cytoskeleton-dependent mechanisms of contractile activity regulation in the smooth muscles]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20090601 |
Mechanism of action of the stimulatory effect of apigenin-6-C-(2''-O-alpha-l-rhamnopyranosyl)-beta-L-fucopyranoside on 14C-glucose uptake. | Chemico-biological interactions 20090515 |
Discovery of substituted N'-(2-oxoindolin-3-ylidene)benzohydrazides as new apoptosis inducers using a cell- and caspase-based HTS assay. | Bioorganic & medicinal chemistry letters 20090515 |
Mechanism of action of N-phenyl-N'-(2-chloroethyl)ureas in the colchicine-binding site at the interface between alpha- and beta-tubulin. | Bioorganic & medicinal chemistry 20090515 |
Recurrent pericarditis due to natalizumab treatment. | Neurology 20090505 |
Colchicine: a novel positive allosteric modulator of the human 5-hydroxytryptamine3A receptor. | The Journal of pharmacology and experimental therapeutics 20090501 |
A retrograde apoptotic signal originating in NGF-deprived distal axons of rat sympathetic neurons in compartmented cultures. | Cell research 20090501 |
Urticarial vasculitis: a unique presentation. | Southern medical journal 20090501 |
Treatment with levamisole and colchicine can result in a significant reduction of IL-6, IL-8 or TNF-alpha level in patients with mucocutaneous type of Behcet's disease. | Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20090501 |
[Bortezomib-induced eruption: Sweet syndrome? Two case reports]. | Annales de dermatologie et de venereologie 20090501 |
Integration of ligand and structure-based virtual screening for the identification of the first dual targeting agent for heat shock protein 90 (Hsp90) and tubulin. | Journal of medicinal chemistry 20090423 |
Whole thoracal spinal cord involvement in case of neuro-Behçet's disease. | Rheumatology international 20090401 |
Grapefruit juice and its constituents augment colchicine intestinal absorption: potential hazardous interaction and the role of p-glycoprotein. | Pharmaceutical research 20090401 |
Treatment of idiopathic retroperitoneal fibrosis with colchicine and steroids: a case series. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20090401 |
Discovery and structure-activity relationships of (2-(arylthio)benzylideneamino)guanidines as a novel series of potent apoptosis inducers. | Bioorganic & medicinal chemistry 20090401 |
Heterocyclic organobismuth(III) compound targets tubulin to induce G2/M arrest in HeLa cells. | Journal of pharmacological sciences 20090401 |
Inhibition of cell proliferation by a resveratrol analog in human pancreatic and breast cancer cells. | Experimental & molecular medicine 20090331 |
Axial stretch of rat single ventricular cardiomyocytes causes an acute and transient increase in Ca2+ spark rate. | Circulation research 20090327 |
Pulling on the heart strings: a new mechanism within Starling's law of the heart? | Circulation research 20090327 |
The novel Akt inhibitor Palomid 529 (P529) enhances the effect of radiotherapy in prostate cancer. | British journal of cancer 20090324 |
AcMNPV EXON0 (AC141) which is required for the efficient egress of budded virus nucleocapsids interacts with beta-tubulin. | Virology 20090315 |
Biological impact of mechanical stimuli on tumor metastasis. | Cell cycle (Georgetown, Tex.) 20090315 |
10-(2-oxo-2-phenylethylidene)-10H-anthracen-9-ones as highly active antimicrotubule agents: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. | Journal of medicinal chemistry 20090312 |
Establishment of a high content assay for the identification and characterisation of bioactivities in crude bacterial extracts that interfere with the eukaryotic cell cycle. | Journal of biotechnology 20090310 |
Inhibition of host cell apoptosis by Eimeria bovis sporozoites. | Veterinary parasitology 20090309 |
[Amyloid goiter: first sign of systemic amyloidosis]. | Annales d'endocrinologie 20090301 |
[Necrotizing folliculitis in Behçet's disease]. | La Revue de medecine interne 20090301 |
Gout attack with unusual ocular complications. | Rheumatology international 20090301 |
Neuroprotective effect of carvedilol, an adrenergic antagonist against colchicine induced cognitive impairment and oxidative damage in rat. | Pharmacology, biochemistry, and behavior 20090301 |
Novel microtubule polymerization inhibitor with potent antiproliferative and antitumor activity. | Cancer research 20090301 |
Systemic treatment in severe cases of recurrent aphthous stomatitis: an open trial. | Clinics (Sao Paulo, Brazil) 20090301 |
Parkin protects dopaminergic neurons against microtubule-depolymerizing toxins by attenuating microtubule-associated protein kinase activation. | The Journal of biological chemistry 20090206 |
Carbendazim inhibits cancer cell proliferation by suppressing microtubule dynamics. | The Journal of pharmacology and experimental therapeutics 20090201 |
Toward docking-based virtual screening for discovering antitubulin agents by targeting taxane and colchicine binding sites. | ChemMedChem 20090201 |
Isolation, structure elucidation and cytotoxic evaluation of endiandrin B from the Australian rainforest plant Endiandra anthropophagorum. | Bioorganic & medicinal chemistry 20090201 |
Up-regulation of connective tissue growth factor in endothelial cells by the microtubule-destabilizing agent combretastatin A-4. | Molecular cancer research : MCR 20090201 |
Trafficking of GFP-AQP5 chimeric proteins conferred with unphosphorylated amino acids at their PKA-target motif ((152)SRRTS) in MDCK-II cells. | The journal of medical investigation : JMI 20090201 |
A 62-year-old man with wrist and hand pain. | Arthritis and rheumatism 20090115 |
Design, synthesis and biological evaluation of novel stilbene-based antitumor agents. | Bioorganic & medicinal chemistry 20090115 |
Dopamine D4 receptors regulate AMPA receptor trafficking and glutamatergic transmission in GABAergic interneurons of prefrontal cortex. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090114 |
Synthesis and biological evaluation of novel symmetry bis-enediynes. | European journal of medicinal chemistry 20090101 |
Wound-healing modulation in upper airway stenosis-Myths and facts. | Head & neck 20090101 |
Medical management of Peyronie's disease. | Journal of andrology 20090101 |
Post-translational regulation of an Aplysia glutamate transporter during long-term facilitation. | Journal of neurochemistry 20090101 |
Randomized trial of pimecrolimus cream plus colchicine tablets versus colchicine tablets in the treatment of genital ulcers in Behçet's disease. | Dermatology (Basel, Switzerland) 20090101 |
Hedgehog pathway inhibitor HhAntag691 is a potent inhibitor of ABCG2/BCRP and ABCB1/Pgp. | Neoplasia (New York, N.Y.) 20090101 |
Post cardiac injury syndrome after uncomplicated coronary angioplasty. | The Journal of invasive cardiology 20090101 |
Healing of ulcers due to cryofibrinogenemia with colchicine and high-dose pentoxifylline. | American journal of clinical dermatology 20090101 |
A comparative study on the anti-angiogenic effects of DNA-damaging and cytoskeletal-disrupting agents. | Angiogenesis 20090101 |
S9, a novel anticancer agent, exerts its anti-proliferative activity by interfering with both PI3K-Akt-mTOR signaling and microtubule cytoskeleton. | PloS one 20090101 |
Heterotopic ossification in systemic sclerosis. | Scandinavian journal of rheumatology 20090101 |
[Clinical features of gout in a cohort of Italian patients]. | Reumatismo 20090101 |
Pronounced linear calcinosis in a boy with mild dermatomyositis. A further possible example of superimposed segmental manifestation of a polygenic disorder. | Dermatology (Basel, Switzerland) 20090101 |
Type 1 diabetes mellitus associated with autoimmune thyroid disease, celiac disease and familial Mediterranean fever: case report. | The Turkish journal of pediatrics 20090101 |
Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers. | Molecular cancer 20090101 |
Induction of tetraploids from petiole explants through colchicine treatments in Echinacea purpurea L. | Journal of biomedicine & biotechnology 20090101 |
The inherited autoinflammatory syndrome: a decade of discovery. | Transactions of the American Clinical and Climatological Association 20090101 |
Origins of an intrinsic hippocampal EEG pattern. | PloS one 20090101 |
[Inhibition of the adenylyl cyclase signaling system by colchicine and vinblastine in ciliate Dileptus anser]. | Tsitologiia 20090101 |
Management of difficult urticaria. | Indian journal of dermatology 20090101 |
SAPHO syndrome with adrenal deficiency: a case report. | Cases journal 20090101 |
Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents. | Journal of medicinal chemistry 20081225 |
Tubulin photoaffinity labeling with biotin-tagged derivatives of potent diketopiperazine antimicrotubule agents. | Chembiochem : a European journal of chemical biology 20081215 |
Benomyl and colchicine synergistically inhibit cell proliferation and mitosis: evidence of distinct binding sites for these agents in tubulin. | Biochemistry 20081209 |
Autoerythrocyte sensitization syndrome (Gardner-Diamond syndrome) associated with cutaneous vasculitis. | Joint, bone, spine : revue du rhumatisme 20081201 |
Regulation of steroid hormone biosynthesis by the cytoskeleton. | Lipids 20081201 |
Deep venous thrombosis and inferior vena cava agenesis causing double crush sciatic neuropathy in Behçet's disease. | Joint, bone, spine : revue du rhumatisme 20081201 |
Simple and rapid extraction, separation, and detection of alkaloids in beverages. | Journal of separation science 20081201 |
Synthesis and characterization of novel natural product-Gd(III) MRI contrast agent conjugates. | Bioorganic & medicinal chemistry letters 20081201 |
Protective effect of quercetin against ICV colchicine-induced cognitive dysfunctions and oxidative damage in rats. | Phytotherapy research : PTR 20081201 |
First impressions. | The American journal of medicine 20081201 |
Penetration and distribution of thiocolchicoside through human skin: comparison between a commercial foam (Miotens) and a drug solution. | AAPS PharmSciTech 20081201 |
Preparation and in-vivo evaluation of (188)Re(CO)(3)-colchicine complex for use as tumor-targeting agent. | Cancer biotherapy & radiopharmaceuticals 20081201 |
[Treatment of acute and recurrent pericarditis. What the clinical cardiologist should know]. | Giornale italiano di cardiologia (2006) 20081201 |
[Study on correlation between effective ingredients of dogwood fruit from genuine producing regions and traits]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081201 |
Rebamipide affects the efficiency of colchicine for the herpes simplex virus-induced inflammation in a Behcet's disease mouse model. | European journal of pharmacology 20081119 |
Simultaneous determination of five toxic alkaloids in body fluids by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081115 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. | Journal of medicinal chemistry 20081113 |
Coexistence of familial Mediterranean fever and psoriasis in a patient with seronegative spondyloarthropathy. | Rheumatology international 20081101 |
WNK3 positively regulates epithelial calcium channels TRPV5 and TRPV6 via a kinase-dependent pathway. | American journal of physiology. Renal physiology 20081101 |
Synthesis and anti-inflammatory structure-activity relationships of thiazine-quinoline-quinones: inhibitors of the neutrophil respiratory burst in a model of acute gouty arthritis. | Bioorganic & medicinal chemistry 20081101 |
Current and future anti-fibrotic therapies for chronic liver disease. | Clinics in liver disease 20081101 |
The effects of colchicine on the progression and regression of encapsulating peritoneal sclerosis. | Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20081101 |
Lower facial contouring with botulinum toxin type A. | The Journal of craniofacial surgery 20081101 |
Should prednisolone be first-line therapy for acute gout? | Lancet (London, England) 20081011 |
[Therapy for gout and pseudogout]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20081010 |
Novel microtubule-interacting phenoxy pyridine and phenyl sulfanyl pyridine analogues for cancer therapy. | Journal of medicinal chemistry 20081009 |
Novel A-ring and B-ring modified combretastatin A-4 (CA-4) analogues endowed with interesting cytotoxic activity. | Journal of medicinal chemistry 20081009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. | Journal of medicinal chemistry 20081009 |
Increased asymmetric dimethylarginine levels in young men with familial Mediterranean fever (FMF): is it early evidence of interaction between inflammation and endothelial dysfunction in FMF? | The Journal of rheumatology 20081001 |
Naphthylphenstatins as tubulin ligands: synthesis and biological evaluation. | Bioorganic & medicinal chemistry 20081001 |
An unusual 'gouty' case of back pain and fever. | The Journal of rheumatology 20081001 |
Neuronal maturation-associated resistance of neurite degeneration caused by trophic factor deprivation or microtubule-disrupting agents. | Brain research 20080916 |
Design, synthesis, and bioactivity of putative tubulin ligands with adamantane core. | Bioorganic & medicinal chemistry letters 20080915 |
Clinical features and risk factors of postsurgical gout. | Annals of the rheumatic diseases 20080901 |
Anti-microtubule activity of tubeimoside I and its colchicine binding site of tubulin. | Cancer chemotherapy and pharmacology 20080901 |
Antimitotic drug injections and radiotherapy: a review of the effectiveness of treatment for hypertrophic scars and keloids. | The international journal of lower extremity wounds 20080901 |
An important differential for ascending weakness. | Internal medicine journal 20080901 |
Structure-activity relationship studies on a novel class of antiproliferative agents derived from Lavendustin A. Part I: Ring A modifications. | Bioorganic & medicinal chemistry 20080815 |
Subcorneal pustular dermatosis (Sneddon-Wilkinson disease) occurring in association with nodal marginal zone lymphoma: a case report. | Dermatology online journal 20080815 |
Discovery of 2-chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine (EP128265, MPI-0441138) as a potent inducer of apoptosis with high in vivo activity. | Journal of medicinal chemistry 20080814 |
Embolia cutis medicamentosa following thiocolchicoside injection. | Journal of the European Academy of Dermatology and Venereology : JEADV 20080801 |
Gastric changes following colchicine therapy in patients with FMF. | Digestive diseases and sciences 20080801 |
Microtubule-targeted drugs inhibit VEGF receptor-2 expression by both transcriptional and post-transcriptional mechanisms. | The Journal of investigative dermatology 20080801 |
Acquired resistance to acetaminophen hepatotoxicity is associated with induction of multidrug resistance-associated protein 4 (Mrp4) in proliferating hepatocytes. | Toxicological sciences : an official journal of the Society of Toxicology 20080801 |
Intrastriatal injection of colchicine induces striatonigral degeneration in mice. | Journal of neurochemistry 20080801 |
cGMP secreted from the tapeworm Hymenolepis diminuta is a signal molecule to the host intestine. | The Journal of parasitology 20080801 |
Aromatic 2-chloroethyl urea derivatives and bioisosteres. Part 2: Cytocidal activity and effects on the nuclear translocation of thioredoxin-1, and the cell cycle progression. | Bioorganic & medicinal chemistry 20080801 |
Synthesis and biological evaluation of new disubstituted analogues of 6-methoxy-3-(3',4',5'-trimethoxybenzoyl)-1H-indole (BPR0L075), as potential antivascular agents. | Bioorganic & medicinal chemistry 20080801 |
Selective alkylation of beta(II)-tubulin and thioredoxin-1 by structurally related subsets of aryl chloroethylureas leading to either anti-microtubules or redox modulating agents. | Bioorganic & medicinal chemistry 20080801 |
Protracted febrile myalgia mimicking polyarteritis nodosa. | Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20080801 |
Eprodisate in amyloid A amyloidosis: a novel therapeutic approach? | Expert opinion on pharmacotherapy 20080801 |
Colchicine: serious interactions. | Prescrire international 20080801 |
Discovery of 4-amino and 4-hydroxy-1-aroylindoles as potent tubulin polymerization inhibitors. | Journal of medicinal chemistry 20080724 |
Lysosomes are the major vesicular compartment undergoing Ca2+-regulated exocytosis from cortical astrocytes. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080723 |
Gold(I)-catalyzed cycloisomerization of 1,7- and 1,8-enynes: application to the synthesis of a new allocolchicinoid. | The Journal of organic chemistry 20080704 |
Effect of serum starvation and chemical inhibitors on cell cycle synchronization of canine dermal fibroblasts. | Theriogenology 20080701 |
Complete recovery of olfactory associative learning by activation of 5-HT4 receptors after dentate granule cell damage in rats. | Neurobiology of learning and memory 20080701 |
Dynorphin in pro-opiomelanocortin neurons of the hypothalamic arcuate nucleus. | Neuroscience 20080626 |
New C5-alkylated indolobenzazepinones acting as inhibitors of tubulin polymerization: cytotoxic and antitumor activities. | Journal of medicinal chemistry 20080626 |
Cycloalkyl-substituted aryl chloroethylureas inhibiting cell cycle progression in G0/G1 phase and thioredoxin-1 nuclear translocation. | Bioorganic & medicinal chemistry letters 20080615 |
Aroyl hydrazones of 2-phenylindole-3-carbaldehydes as novel antimitotic agents. | Bioorganic & medicinal chemistry 20080615 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). | Journal of medicinal chemistry 20080612 |
Kaempferol and quercetin stimulate granulocyte-macrophage colony-stimulating factor secretion in human prostate cancer cells. | Molecular and cellular endocrinology 20080611 |
The efficacy of anakinra in an adolescent with colchicine-resistant familial Mediterranean fever. | European journal of pediatrics 20080601 |
The roles of cys124 and ser239 in the functional properties of human betaIII tubulin. | Cell motility and the cytoskeleton 20080601 |
Inhibitors of tubulin polymerization: synthesis and biological evaluation of hybrids of vindoline, anhydrovinblastine and vinorelbine with thiocolchicine, podophyllotoxin and baccatin III. | Bioorganic & medicinal chemistry 20080601 |
The cloning of eel osmotic stress transcription factor and the regulation of its expression in primary gill cell culture. | The Journal of experimental biology 20080601 |
Significant antitumor activity in vivo following treatment with the microtubule agent ENMD-1198. | Molecular cancer therapeutics 20080601 |
Involvement of cytoskeletal integrity in the regulation of Cl- and amylase secretion from rat parotid acinar cells. | Biomedical research (Tokyo, Japan) 20080601 |
Treatment of gout attacks. | Prescrire international 20080601 |
Forensic norms of female and male Lebanese adults. | The Journal of forensic odonto-stomatology 20080601 |
Colchicine inhibits intimal hyperplasia and leukocyte VEGF expression in dogs. | The Journal of surgical research 20080515 |
Design, synthesis, and biological evaluation of thiophene analogues of chalcones. | Bioorganic & medicinal chemistry 20080515 |
2-(6-aryl-3(Z)-hexen-1,5-diynyl)anilines as a new class of potent antitubulin agents. | Journal of medicinal chemistry 20080508 |
Stilbene derivatives that are colchicine-site microtubule inhibitors have antileukemic activity and minimal systemic toxicity. | American journal of hematology 20080501 |
An estrogen metabolite, 2-methoxyestradiol, disrupts cardiac microtubules and unmasks muscarinic inhibition of calcium current. | The Journal of pharmacology and experimental therapeutics 20080501 |
Bullwhip neurons in the retina regulate the size and shape of the eye. | Developmental biology 20080501 |
Colchicine-induced neuromyopathy in a patient with chronic renal failure: the role of clarithromycin. | The Netherlands journal of medicine 20080501 |
The genotoxicity of vitamin C in vitro. | Bosnian journal of basic medical sciences 20080501 |
Therapeutic alternatives for chronic urticaria: an evidence-based review, part 1. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20080501 |
Efficacy of thiocolchicoside in Indian patients suffering from low back pain associated with muscle spasm. | Journal of the Indian Medical Association 20080501 |
Isoindolo[2,1-a]quinoxaline derivatives, novel potent antitumor agents with dual inhibition of tubulin polymerization and topoisomerase I. | Journal of medicinal chemistry 20080424 |
Synthesis and structure-activity relationship studies on tryprostatin A, an inhibitor of breast cancer resistance protein. | Bioorganic & medicinal chemistry 20080415 |
Ruthenium(II) complexes of 2-benzoylpyridine-derived thiosemicarbazones with cytotoxic activity against human tumor cell lines. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080401 |
Refractory idiopathic thrombocytopenic purpura treated with the soluble tumor necrosis factor receptor etanercept. | American journal of hematology 20080401 |
Identification of novel metabolites of colchicine in rat bile facilitated by enhanced online radiometric detection. | Drug metabolism and disposition: the biological fate of chemicals 20080401 |
Disposition and metabolism of the colchicine derivative [14C]-ZD6126 in rat and dog. | Xenobiotica; the fate of foreign compounds in biological systems 20080401 |
Gout and related morbid conditions: pharmacological and SPA therapy. | Minerva medica 20080401 |
[Pharmacological therapy of keloids in an athymic mouse model]. | Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... 20080401 |
Tubulin as a binding partner of the heag2 voltage-gated potassium channel. | The Journal of membrane biology 20080401 |
What is your diagnosis? Gout. | JAAPA : official journal of the American Academy of Physician Assistants 20080401 |
[Adamantiades-Behçet's disease. Clinical review]. | Medizinische Klinik (Munich, Germany : 1983) 20080315 |
[Behçet's disease]. | La Revue du praticien 20080315 |
Synthesis and biological evaluation of 1-methyl-2-(3',4',5'-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors. | Journal of medicinal chemistry 20080313 |
Natural and synthetic polymers as inhibitors of drug efflux pumps. | Pharmaceutical research 20080301 |
Beneficial drugs for liver diseases. | Journal of applied toxicology : JAT 20080301 |
Nuclear receptor agonists improve insulin responsiveness in cultured cardiomyocytes through enhanced signaling and preserved cytoskeletal architecture. | Endocrinology 20080301 |
Docking and hydropathic scoring of polysubstituted pyrrole compounds with antitubulin activity. | Bioorganic & medicinal chemistry 20080301 |
Effects of neuropeptide F on regeneration in Girardia tigrina (Platyhelminthes). | Cell and tissue research 20080301 |
DNA low-density array analysis of colchicine neurotoxicity in rat cerebellar granular neurons. | Neurotoxicology 20080301 |
Gastrointestinal tract epithelial changes associated with taxanes: marker of drug toxicity versus effect. | The American journal of surgical pathology 20080301 |
Recurrent multifocal primary amyloidosis of urinary bladder. | Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20080301 |
Hepatobiliary excretion and enterohepatic circulation of colchicine in rats. | International journal of pharmaceutics 20080227 |
Two cases of acute leukopenia induced by colchicine with concurrent immunosuppressants use in Behçet's disease. | Yonsei medical journal 20080227 |
RNAi of mitotic cyclins in Drosophila uncouples the nuclear and centrosome cycle. | Current biology : CB 20080226 |
A comparative molecular field and comparative molecular similarity indices analyses (CoMFA and CoMSIA) of N-phenyl-N'-(2-chloroethyl)ureas targeting the colchicine-binding site as anticancer agents. | Bioorganic & medicinal chemistry 20080215 |
Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. 4. Structure-activity relationships of N-alkyl substituted pyrrole fused at the 7,8-positions. | Journal of medicinal chemistry 20080214 |
N-Phenyl-N'-(2-chloroethyl)ureas (CEUs) as potential antineoplastic agents. Part 3: role of carbonyl groups in the covalent binding to the colchicine-binding site. | Bioorganic & medicinal chemistry 20080201 |
Colchicine attenuates compensation to negative but not to positive lenses in young chicks. | Experimental eye research 20080201 |
Involvement of the cytoskeleton in the effect of PGE2 on ion transport in the rat distal colon. | Prostaglandins & other lipid mediators 20080201 |
Microchip micellar electrokinetic chromatography separation of alkaloids with UV-absorbance spectral detection. | Electrophoresis 20080201 |
Fluid and osmolyte recovery in the common pond snail Lymnaea stagnalis following full-body withdrawal. | The Journal of experimental biology 20080201 |
Urate crystals, inflammation, and colchicine. | Arthritis and rheumatism 20080201 |
Polymorphonuclear leukocyte motility in vitro: IV. Colchicine inhibition of chemotactic activity formation after phagocytosis of urate crystals. | Arthritis and rheumatism 20080201 |
Cough, fever, joint pain and tender nodules: what is your call? | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20080115 |
Anti-mitotic activity of colchicine and the structural basis for its interaction with tubulin. | Medicinal research reviews 20080101 |
Fatal toxic myopathy attributed to propofol, methylprednisolone, and cyclosporine after prior exposure to colchicine and simvastatin. | Clinical rheumatology 20080101 |
Caveolin-3 expression and caveolae are required for isoflurane-induced cardiac protection from hypoxia and ischemia/reperfusion injury. | Journal of molecular and cellular cardiology 20080101 |
Intravitreal colchicine causes decreased RNFL birefringence without altering RNFL thickness. | Investigative ophthalmology & visual science 20080101 |
Endocytosis inhibitors prevent poly(amidoamine) dendrimer internalization and permeability across Caco-2 cells. | Molecular pharmaceutics 20080101 |
A new type of microtubular cytoskeleton in microsporogenesis of Lavatera thuringiaca L. | Protoplasma 20080101 |
A child with Behçet's disease presenting with a spectrum of inflammatory manifestations including epididymoorchitis. | The Turkish journal of pediatrics 20080101 |
Acute myocardial infarction and ascending aortic aneurysm in a child with Behçet's disease. | The Turkish journal of pediatrics 20080101 |
Central venous thrombosis in Behcet's disease. | Angiology 20080101 |
Urticaria unresponsive to antihistaminic treatment: an open study of therapeutic options based on histopathologic features. | The Journal of dermatological treatment 20080101 |
Colchicine, cyclophosphamide and prednisone in the treatment of mild-moderate idiopathic pulmonary fibrosis: comparison of three currently available therapeutic regimens. | European review for medical and pharmacological sciences 20080101 |
Efficacy and safety of eperisone in patients with low back pain: a double blind randomized study. | European review for medical and pharmacological sciences 20080101 |
[Sclerosing mesenteritis. Presentation of three cases and review of the literature]. | Cirugia y cirujanos 20080101 |
Clinical resolution of facial cutaneous sarcoidosis with systemic colchicine and a topical corticosteroid ointment. | Comprehensive therapy 20080101 |
Gout. | BMJ clinical evidence 20080101 |
Allocolchicines via intramolecular Nicholas reactions: the synthesis of NSC 51046. | Organic letters 20071220 |
Luminescence studies of perturbation of tryptophan residues of tubulin in the complexes of tubulin with colchicine and colchicine analogues. | Biochemistry 20071218 |
p38 and JNK MAPK, but not ERK1/2 MAPK, play important role in colchicine-induced cortical neurons apoptosis. | European journal of pharmacology 20071208 |
Etiologic agents of diarrhea in solid organ recipients. | Transplant infectious disease : an official journal of the Transplantation Society 20071201 |
A novel mutation of the familial Mediterranean fever gene in a Greek family related to a non-classical, variably expressed FMF phenotype. | Rheumatology international 20071201 |
[(2-Phenylindol-3-yl)methylene]propanedinitriles inhibit the growth of breast cancer cells by cell cycle arrest in G(2)/M phase and apoptosis. | Bioorganic & medicinal chemistry 20071201 |
New functional assay of P-glycoprotein activity using Hoechst 33342. | Bioorganic & medicinal chemistry 20071201 |
Compensatory membrane expression of the V-ATPase B2 subunit isoform in renal medullary intercalated cells of B1-deficient mice. | American journal of physiology. Renal physiology 20071201 |
Specific reversal of multidrug resistance to colchicine in CEM/VLB(100) cells by Gynostemma pentaphyllum extract. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20071201 |
Pattern analysis of microtubule-polymerizing and -depolymerizing agent combinations as cancer chemotherapies. | International journal of oncology 20071201 |
Nodular scleritis and Sweet's syndrome. | Clinical & experimental ophthalmology 20071201 |
Sulfonate derivatives of naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-anthracenone as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization. | Journal of medicinal chemistry 20071129 |
Colchicine prescribing and safety monitoring in patients with gout. | The New Zealand medical journal 20071109 |
[Behçet disease and hemoptysis]. | La Revue de medecine interne 20071101 |
Tight junction targeting and intracellular trafficking of occludin in polarized epithelial cells. | American journal of physiology. Cell physiology 20071101 |
[European League Against Rheumatism evidence-based recommendations for diagnosis and management of gout]. | Zeitschrift fur Rheumatologie 20071101 |
Treatment of alcoholic liver disease. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20071101 |
BIN4, a novel component of the plant DNA topoisomerase VI complex, is required for endoreduplication in Arabidopsis. | The Plant cell 20071101 |
Differential colchicine-binding across eukaryotic families: the role of highly conserved Pro268beta and Ala248beta residues in animal tubulin. | FEBS letters 20071030 |
Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants. | Molecular cell 20071026 |
Discovery and investigation of antiproliferative and apoptosis-inducing properties of new heterocyclic podophyllotoxin analogues accessible by a one-step multicomponent synthesis. | Journal of medicinal chemistry 20071018 |
Concordance of the management of chronic gout in a UK primary-care population with the EULAR gout recommendations. | Annals of the rheumatic diseases 20071001 |
Pro-inflammatory cellular immune response in Behçet's disease. | Rheumatology international 20071001 |
Effect of oral D-penicillamine vs. colchicine on experimentally induced peritoneal adhesions in rats. | Fertility and sterility 20071001 |
Rotenone selectively kills serotonergic neurons through a microtubule-dependent mechanism. | Journal of neurochemistry 20071001 |
Dual role of tubulin-cytoskeleton in store-operated calcium entry in human platelets. | Cellular signalling 20071001 |
Inhibitory effects of ginsenosides and their hydrolyzed metabolites on daunorubicin transport in KB-C2 cells. | Biological & pharmaceutical bulletin 20071001 |
Colchicine, a microtubule depolymerizing agent, inhibits myocardial apoptosis in rats. | The Tohoku journal of experimental medicine 20071001 |
Rapid onset of muscle weakness (rhabdomyolysis) associated with the combined use of simvastatin and colchicine. | Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20071001 |
Changes in serum carbonyl and malondialdehyde levels following colchicine and vitamin E treatment in Behcet's disease. | Methods and findings in experimental and clinical pharmacology 20071001 |
[Simultaneous screening for 22 poisonous alkaloids in blood by liquid chromatography-tandem mass spectrometry with multiple-reaction monitoring]. | Fa yi xue za zhi 20071001 |
Determination of (-)-demecolcine and (-)-colchicine content in selected Jordanian Colchicum species. | Die Pharmazie 20071001 |
Insight into the GTPase activity of tubulin from complexes with stathmin-like domains. | Biochemistry 20070918 |
Secretion of apolipoprotein E from macrophages occurs via a protein kinase A and calcium-dependent pathway along the microtubule network. | Circulation research 20070914 |
Eprodisate in AA amyloidosis. | The New England journal of medicine 20070913 |
Early ultrasonographic markers of atherosclerosis in patients with familial Mediterranean fever. | Clinical rheumatology 20070901 |
Protracted familial mediterranean fever arthritis presenting as septic arthritis. | Rheumatology international 20070901 |
Treatment of refractory recurrent pericarditis. | Journal of cardiovascular medicine (Hagerstown, Md.) 20070901 |
Fluoxetine and the dentate gyrus: memory, recovery of function, and electrophysiology. | Behavioural pharmacology 20070901 |
Determination of colchicine in mouse plasma by high performance liquid-chromatographic method with UV detection and its application to pharmacokinetic studies. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20070901 |
Effect of curcumin on intracerebroventricular colchicine-induced cognitive impairment and oxidative stress in rats. | Journal of medicinal food 20070901 |
The effect of all-trans retinoic acid and/or colchicine on expression of rexinoid and thyroid hormone nuclear receptors and their coregulators in primary rat hepatocytes. | General physiology and biophysics 20070901 |
Role of cholinoceptors recycling in short-term potentiation of cholinosensitivity of command neurons in edible snail. | Bulletin of experimental biology and medicine 20070901 |
[Involvement of the foot in metabolic diseases]. | Praxis 20070822 |
Optimum conditions for detecting hepatic micronuclei caused by numerical chromosome aberration inducers in mice. | Mutation research 20070815 |
[Etiological mechanism of peripheral nervous system diseases induced by drug therapy]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20070810 |
Characterization of the intracellular mechanisms involved in the antiaggregant properties of cinnamtannin B-1 from bay wood in human platelets. | Journal of medicinal chemistry 20070809 |
Effects of antifibrotic agents on TGF-beta1, CTGF and IFN-gamma expression in patients with idiopathic pulmonary fibrosis. | Respiratory medicine 20070801 |
Ganoderma lucidum polysaccharides enhance CD14 endocytosis of LPS and promote TLR4 signal transduction of cytokine expression. | Journal of cellular physiology 20070801 |
Antitrypanosomal activity of triterpenoids and sterols from the leaves of Strychnos spinosa and related compounds. | Journal of natural products 20070801 |
Aquatic ecotoxicology approaches in Western Mexico. | Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20070801 |
A bifunctional colchicinoid that binds to the androgen receptor. | Molecular cancer therapeutics 20070801 |
[Effect of the microtubule depolymerization on mitochondria damage in rat myocardiocytes early after hypoxia]. | Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20070801 |
Antiproliferative and apoptosis inducing properties of pyrano[3,2-c]pyridones accessible by a one-step multicomponent synthesis. | Bioorganic & medicinal chemistry letters 20070715 |
Mammalian Sir2-related protein (SIRT) 2-mediated modulation of resistance to axonal degeneration in slow Wallerian degeneration mice: a crucial role of tubulin deacetylation. | Neuroscience 20070713 |
Discovery of novel antitumor antimitotic agents that also reverse tumor resistance. | Journal of medicinal chemistry 20070712 |
Spectroscopic studies of charge transfer complexes between colchicine and some pi acceptors. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070701 |
Ca2+ dependence of flow-stimulated K secretion in the mammalian cortical collecting duct. | American journal of physiology. Renal physiology 20070701 |
Severe colchicine-induced bilateral optico-neuromyopathy. | Muscle & nerve 20070701 |
Selective knockdown of AT1 receptors by RNA interference inhibits Val5-ANG II endocytosis and NHE-3 expression in immortalized rabbit proximal tubule cells. | American journal of physiology. Cell physiology 20070701 |
Identification and characterization of a new tubulin-binding tetrasubstituted brominated pyrrole. | Molecular pharmacology 20070701 |
Alkylation potency and protein specificity of aromatic urea derivatives and bioisosteres as potential irreversible antagonists of the colchicine-binding site. | Bioorganic & medicinal chemistry 20070701 |
Association of drug transporter gene ABCB1 (MDR1) 3435C to T polymorphism with colchicine response in familial Mediterranean fever. | The Journal of rheumatology 20070701 |
Treatment of acute gout in hospitalized patients. | The Journal of rheumatology 20070701 |
[Pathogenesis and treatment of intestinal Behçet's disease]. | The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20070701 |
Cdk1 phosphorylation sites on Cdc27 are required for correct chromosomal localisation and APC/C function in syncytial Drosophila embryos. | Journal of cell science 20070615 |
Quality of care for gout in the US needs improvement. | Arthritis and rheumatism 20070615 |
Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure-activity relationships and molecular modeling studies. | Journal of medicinal chemistry 20070614 |
Synthesis of the tricyclic core of colchicine via a dienyne tandem ring-closing metathesis reaction. | Organic letters 20070607 |
Long-term colchicine therapy in a patient with Behçet's disease and acute promyelocytic leukemia. | Rheumatology international 20070601 |
Effects of the myotoxic Lys49 phospholipase A2 from Agkistrodon contortrix laticinctus snake venom on water transport in the toad bladder epithelium: evidence for a role of microtubules and calmodulin. | Toxicology in vitro : an international journal published in association with BIBRA 20070601 |
Plasma membrane delivery, endocytosis and turnover of transcobalamin receptor in polarized human intestinal epithelial cells. | The Journal of physiology 20070601 |
German evidence-based guidelines for the treatment of Psoriasis vulgaris (short version). | Archives of dermatological research 20070601 |
Prolonged urticaria with purpura: the spectrum of clinical and histopathologic features in a prospective series of 22 patients exhibiting the clinical features of urticarial vasculitis. | Journal of the American Academy of Dermatology 20070601 |
BDNF induces transport of PSD-95 to dendrites through PI3K-AKT signaling after NMDA receptor activation. | Nature neuroscience 20070601 |
[Introduction of hexaploid of Chinese narcissus and analysis of its chromosome change]. | Fen zi xi bao sheng wu xue bao = Journal of molecular cell biology 20070601 |
Cytotoxicity of colchicine derivatives in primary cultures of human hepatocytes. | Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20070601 |
[The influence of microtubule intervention drugs on the energy metabolism of myocardial cells after hypoxia]. | Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20070601 |
Novel 3-O-glycosyl-3-demethylthiocolchicines as ligands for glycine and gamma-aminobutyric acid receptors. | Journal of medicinal chemistry 20070503 |
Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization. | Journal of medicinal chemistry 20070503 |
Rapid and sensitive liquid chromatography-tandem mass spectrometry method for the quantitation of colchicine in human plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501 |
Mechanism of in vivo sister-chromatid exchange induction by 5-azacytidine. | Mutagenesis 20070501 |
Juvenile psoriatic arthritis carrying familial Mediterranean fever gene mutations in a 14-year-old Turkish girl. | The Journal of dermatology 20070501 |
Optimization of solvents for effective isolation of colchicines from Gloriosa superba L. seeds. | Natural product research 20070501 |
Acute colchicine intoxication in a child: a case report. | Pediatric emergency care 20070501 |
Prevention of colchicine toxicity in patients with gout. | The New Zealand medical journal 20070413 |
A placebo-controlled comparison of the efficiency of triple- and monotherapy in category III B chronic pelvic pain syndrome (CPPS). | European urology 20070401 |
Actin disruption inhibits endosomal traffic of P-glycoprotein-EGFP and resistance to daunorubicin accumulation. | American journal of physiology. Cell physiology 20070401 |
Biophysical characterization of MDR breast cancer cell lines reveals the cytoplasm is critical in determining drug sensitivity. | Biochimica et biophysica acta 20070401 |
N-Phenyl-N'-(2-chloroethyl)urea analogues of combretastatin A-4: Is the N-phenyl-N'-(2-chloroethyl)urea pharmacophore mimicking the trimethoxy phenyl moiety? | Bioorganic & medicinal chemistry letters 20070401 |
Triterpenoids from the floral spikes of Betula platyphylla var. japonica and their reversing activity against multidrug-resistant cancer cells. | Journal of natural products 20070401 |
Amyloidosis: a changing clinical perspective. | Hematology (Amsterdam, Netherlands) 20070401 |
Taxol normalizes the impaired agonist-induced beta2-adrenoceptor internalization in splenocytes from GRK2+/- mice. | European journal of pharmacology 20070329 |
Skin permeation enhancement potential of Aloe Vera and a proposed mechanism of action based upon size exclusion and pull effect. | International journal of pharmaceutics 20070321 |
Polycystin-2 cation channel function in the human syncytiotrophoblast is regulated by microtubular structures. | The Journal of physiology 20070315 |
Synthesis and biological activity of 2,5-diaryl-3-methylpyrimido[4,5-c]quinolin-1(2H)-one derivatives. | Bioorganic & medicinal chemistry 20070315 |
Expression, protein stability and transcriptional activity of retinoic acid receptors are affected by microtubules interfering agents and all-trans-retinoic acid in primary rat hepatocytes. | Molecular and cellular endocrinology 20070315 |
Effect of colchicine (0.5 mg twice daily) on high-sensitivity C-reactive protein independent of aspirin and atorvastatin in patients with stable coronary artery disease. | The American journal of cardiology 20070315 |
Thiocolchicoside inhibits the activity of various subtypes of recombinant GABA(A) receptors expressed in Xenopus laevis oocytes. | European journal of pharmacology 20070308 |
Potent antitubulin tumor cell cytotoxins based on 3-aroyl indazoles. | Journal of medicinal chemistry 20070308 |
Spatial organization and dynamic properties of neurotransmitter release sites in the enteric nervous system. | Neuroscience 20070302 |
Expression and transcriptional activities of nuclear receptors involved in regulation of drug-metabolizing enzymes are not altered by colchicine: focus on PXR, CAR, and GR in primary human hepatocytes. | Cell biology and toxicology 20070301 |
Serum-soluble selectin levels in patients with Behçet's disease. | Clinical rheumatology 20070301 |
Host filamentous actin is associated with Heliothis armigera single nucleopolyhedrosis virus (HaSNPV) nucleocapsid transport to the host nucleus. | Current microbiology 20070301 |
Major arterial involvement and review of Behcet's disease. | Annals of vascular surgery 20070301 |
Updates in the management of gout. | The American journal of medicine 20070301 |
[Fatal Sweet syndrome associated to chronic idiopathic systemic inflammatory response syndrome]. | Actas dermo-sifiliograficas 20070301 |
Highly potent triazole-based tubulin polymerization inhibitors. | Journal of medicinal chemistry 20070222 |
Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites. | Nature chemical biology 20070201 |
Iatrogenic rheumatic syndromes in the elderly. | Rheumatic diseases clinics of North America 20070201 |
Synthesis and SAR of [1,2,4]triazolo[1,5-a]pyrimidines, a class of anticancer agents with a unique mechanism of tubulin inhibition. | Journal of medicinal chemistry 20070125 |
Zinc and the cytoskeleton in the neuronal modulation of transcription factor NFAT. | Journal of cellular physiology 20070101 |
Neuroprotective effects of resveratrol against intracerebroventricular colchicine-induced cognitive impairment and oxidative stress in rats. | Pharmacology 20070101 |
Formation of filopodia in earthworm (Lumbricus terrestris) coelomocytes in response to osmotic stress. | Zoology (Jena, Germany) 20070101 |
Tophaceous gout of the lumbar spine mimicking pyogenic discitis. | The spine journal : official journal of the North American Spine Society 20070101 |
Selective serotonin reuptake inhibitors reduce the attack frequency in familial mediterranean Fever. | The Tohoku journal of experimental medicine 20070101 |
Interaction between Bluetongue virus outer capsid protein VP2 and vimentin is necessary for virus egress. | Virology journal 20070101 |
Miliarial gout (a new entity). | Journal of cutaneous medicine and surgery 20070101 |
Colchicine overdose-induced acute renal failure and electrolyte imbalance. | Renal failure 20070101 |
Kinetic radical-scavenging activity of colchicine and tropolone. | In vivo (Athens, Greece) 20070101 |
Colchicines-induced neurotoxicity as an animal model of sporadic dementia of Alzheimer's type. | Pharmacological reports : PR 20070101 |
Hyperuricemia and gout: new insights into pathogenesis and treatment. | Bulletin of the NYU hospital for joint diseases 20070101 |
Plasma and platelet serotonin levels in familial Mediterranean fever. | Clinical and experimental rheumatology 20070101 |
9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents-synthesis, antiproliferative activity, and inhibition of tubulin polymerization. | Journal of medicinal chemistry 20061228 |
Sexually dimorphic immunoreactivity of galanin and colocalization with arginine vasotocin in the chicken brain (Gallus gallus domesticus). | The Journal of comparative neurology 20061210 |
Polycystin-2 cation channel function is under the control of microtubular structures in primary cilia of renal epithelial cells. | The Journal of biological chemistry 20061208 |
Differential effects of cyclooxygenase inhibitors on intracerebroventricular colchicine-induced dysfunction and oxidative stress in rats. | European journal of pharmacology 20061203 |
Successful treatment of nephrotic syndrome due to FMF amyloidosis with azathioprine: report of three Turkish cases. | Rheumatology international 20061201 |
Effect of acrylamide on the cytoskeleton and apoptosis of bovine lens epithelial cells. | Cell biology international 20061201 |
Comparison of the mutagenic potential of 17 physical and chemical agents analyzed by the flow cytometry mutation assay. | Mutation research 20061201 |
Colchicine and HMG Co-A reductase inhibitors induced myopathy-a case report. | Neurotoxicology 20061201 |
Induction of DNA synthesis in Anopheles albimanus tissue cultures in response to a Saccharomyces cerevisiae challenge. | Archives of insect biochemistry and physiology 20061201 |
Microtubule contribution to the reflectance of the retinal nerve fiber layer. | Investigative ophthalmology & visual science 20061201 |
Skin atrophy caused by thiocolchicoside injections. | International journal of dermatology 20061201 |
Pathogenesis, clinical findings and management of acute and chronic gout. | Minerva medica 20061201 |
[What is your diagnosis? Acute gout attack]. | Praxis 20061129 |
Colchicine glycorandomization influences cytotoxicity and mechanism of action. | Journal of the American Chemical Society 20061108 |
Effectiveness of interventions for the treatment of acute and prevention of recurrent gout--a systematic review. | Rheumatology (Oxford, England) 20061101 |
Colchicine vs. omega-3 fatty acids for prevention of chronic cyclosporine nephrotoxicity in Sprague Dawley rats: an experimental animal model. | Archives of medical research 20061101 |
Case 1: differential diagnosis of an acute gouty attack. | The American journal of medicine 20061101 |
[Periodic fever syndromes]. | Zeitschrift fur Rheumatologie 20061101 |
Cyclosporine not the only agent to cause Guillain-Barré-like syndrome after solid-organ transplant. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20061101 |
Chronic exposure to particulate chromate induces spindle assembly checkpoint bypass in human lung cells. | Chemical research in toxicology 20061101 |
New therapies in hepatitis C virus and chronic liver disease: antifibrotics. | Clinics in liver disease 20061101 |
Synthesis and antitumor activity of nitrogen-based thiocolchicine derivatives. | Yao xue xue bao = Acta pharmaceutica Sinica 20061101 |
2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents. | Journal of medicinal chemistry 20061019 |
Colchicine delays the development of hepatocellular carcinoma in patients with hepatitis virus-related liver cirrhosis. | Cancer 20061015 |
Differential effects of hydroxyacetophenone analogues on the transcytotic vesicular pathway in rat liver. | European journal of pharmacology 20061010 |
Roles of microfilaments and microtubules in paxillin dynamics. | Biochemical and biophysical research communications 20061006 |
The management of gout at an academic healthcare center in Beijing: a physician survey. | The Journal of rheumatology 20061001 |
A survey of current evaluation and treatment of gout. | The Journal of rheumatology 20061001 |
Active ammonia absorption in the midgut of the Tobacco hornworm Manduca sexta L.: transport studies and mRNA expression analysis of a Rhesus-like ammonia transporter. | Insect biochemistry and molecular biology 20061001 |
Microtubules are required for NF-kappaB nuclear translocation in neuroblastoma IMR-32 cells: modulation by zinc. | Journal of neurochemistry 20061001 |
Identification and functional expression of a carrier-mediated riboflavin transport system on rabbit corneal epithelium. | Current eye research 20061001 |
Liquid chromatography-tandem mass spectrometry for the determination of colchicine in postmortem body fluids. Case report of two fatalities and review of the literature. | Journal of analytical toxicology 20061001 |
Neurotrophic factors stabilize microtubules and protect against rotenone toxicity on dopaminergic neurons. | The Journal of biological chemistry 20060929 |
[Recurrent autoreactive pericardial effusion. Impact of an aetiological classification of pericarditis]. | Deutsche medizinische Wochenschrift (1946) 20060929 |
Design and biological evaluation of novel tubulin inhibitors as antimitotic agents using a pharmacophore binding model with tubulin. | Journal of medicinal chemistry 20060921 |
[4-(imidazol-1-yl)thiazol-2-yl]phenylamines. A novel class of highly potent colchicine site binding tubulin inhibitors: synthesis and cytotoxic activity on selected human cancer cell lines. | Journal of medicinal chemistry 20060921 |
Tubulin polymerization inhibitors with a fluorinated phthalimide skeleton derived from thalidomide. | Bioorganic & medicinal chemistry letters 20060915 |
Adherent and invasive Escherichia coli are associated with persistent bovine mastitis. | Veterinary microbiology 20060910 |
Microtubules and actin microfilaments regulate lipid raft/caveolae localization of adenylyl cyclase signaling components. | The Journal of biological chemistry 20060908 |
3-demethoxy-3-glycosylaminothiocolchicines: Synthesis of a new class of putative muscle relaxant compounds. | Journal of medicinal chemistry 20060907 |
Calpastatin overexpression prevents progression of S-1,2-dichlorovinyl-l-cysteine (DCVC)-initiated acute renal injury and renal failure (ARF) in diabetes. | Toxicology and applied pharmacology 20060901 |
Clinical significance of P46L and R92Q substitutions in the tumour necrosis factor superfamily 1A gene. | Annals of the rheumatic diseases 20060901 |
Mechanism underlying flow stimulation of sodium absorption in the mammalian collecting duct. | American journal of physiology. Renal physiology 20060901 |
Effects of hyposmotic stress on exocytosis in isolated turbot, Scophthalmus maximus, hepatocytes. | Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20060901 |
Pyoderma gangrenosum as initial manifestation of Graves' disease. | Clinical and experimental dermatology 20060901 |
The muscle relaxant thiocolchicoside is an antagonist of GABAA receptor function in the central nervous system. | Neuropharmacology 20060901 |
An unusual presentation of polyarticular tophaceous gout. | Rheumatology (Oxford, England) 20060901 |
[Pulmonary embolism and Behçet's disease]. | Archives des maladies du coeur et des vaisseaux 20060901 |
[Idiopathic interstitial pneumonia: treatment]. | Revue des maladies respiratoires 20060901 |
Application of aryl siloxane cross-coupling to the synthesis of allocolchicinoids. | Organic letters 20060831 |
SFTG international collaborative study on in vitro micronucleus test II. Using human lymphocytes. | Mutation research 20060804 |
SFTG international collaborative study on in vitro micronucleus test IV. Using CHL cells. | Mutation research 20060804 |
SFTG international collaborative study on in vitro micronucleus test V. Using L5178Y cells. | Mutation research 20060804 |
SFTG international collaborative study on in vitro micronucleus test I. General conditions and overall conclusions of the study. | Mutation research 20060804 |
AT1 receptor-mediated accumulation of extracellular angiotensin II in proximal tubule cells: role of cytoskeleton microtubules and tyrosine phosphatases. | American journal of physiology. Renal physiology 20060801 |
Preplaced cell division: a critical mechanism of autoprotection against S-1,2-dichlorovinyl-L-cysteine-induced acute renal failure and death in mice. | American journal of physiology. Renal physiology 20060801 |
Inhibition of the MDR1 transporter by new phenothiazine derivatives. | Biochemical and biophysical research communications 20060721 |
Role of the sodium-dependent phosphate co-transporters and of the phosphate complexes of uranyl in the cytotoxicity of uranium in LLC-PK1 cells. | Toxicology and applied pharmacology 20060715 |
Identification of tubulin as the molecular target of proapoptotic pyrrolo-1,5-benzoxazepines. | Molecular pharmacology 20060701 |
Neurotensin afferents of the ventral tegmental area in the rat: [1] re-examination of their origins and [2] responses to acute psychostimulant and antipsychotic drug administration. | The European journal of neuroscience 20060701 |
Colchicine therapy and the cognitive status of elderly patients with familial Mediterranean fever. | The Israel Medical Association journal : IMAJ 20060701 |
Behçet's disease in an HIV-1-infected patient treated with highly active antiretroviral therapy. | The Israel Medical Association journal : IMAJ 20060701 |
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents. | Journal of medicinal chemistry 20060629 |
Axonal transport of human immunodeficiency virus type 1 envelope protein glycoprotein 120 is found in association with neuronal apoptosis. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060621 |
Transmembrane segment 1 of human P-glycoprotein contributes to the drug-binding pocket. | The Biochemical journal 20060615 |
Novel combretastatin analogues endowed with antitumor activity. | Journal of medicinal chemistry 20060601 |
Sweet's syndrome from an Indian perspective: a report of four cases and review of the literature. | International journal of dermatology 20060601 |
[Polyarticular gout in young adults: a curable rheumatic disease]. | Medecine tropicale : revue du Corps de sante colonial 20060601 |
[Effect of the ethyl acetate extract of zhi ju zi on serum makers and the expression of TGF-beta1 in rats with hepatic fibrosis]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060601 |
Oxalone and lactone moieties of podophyllotoxin exhibit properties of both the B and C rings of colchicine in its binding with tubulin. | Biochemistry 20060523 |
Synthesis and biological evaluation of B-ring modified colchicine and isocolchicine analogs. | Bioorganic & medicinal chemistry letters 20060515 |
[Badly managed gout for decades. Only then do the hands look this way]. | MMW Fortschritte der Medizin 20060504 |
Electrochemistry and voltammetric determination of colchicine using an acetylene black-dihexadecyl hydrogen phosphate composite film modified glassy carbon electrode. | Bioelectrochemistry (Amsterdam, Netherlands) 20060501 |
Colchicine-induced polyploidization depends on tubulin polymerization in c-metaphase cells. | Protoplasma 20060501 |
[Hyperuricemia and gout: diagnosis and therapy]. | Der Internist 20060501 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
[Atypical crowned dens syndrome]. | Presse medicale (Paris, France : 1983) 20060501 |
[Preparation and characterization of transfersomes of three drugs in vitro]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060501 |
Zinquin identifies subcellular compartmentalization of zinc in cortical neurons. Relation to the trafficking of zinc and the mitochondrial compartment. | Brain research 20060426 |
The cycloaddition strategy for the synthesis of natural products containing carbocyclic seven-membered rings. | Chemistry (Weinheim an der Bergstrasse, Germany) 20060424 |
Benzoylphenylurea sulfur analogues with potent antitumor activity. | Journal of medicinal chemistry 20060406 |
Neuro-Behçet syndrome presenting as acute meningeal syndrome. | The Journal of infection 20060401 |
Interleukin-6 and nitric oxide synthase expression in the vasopressin and corticotrophin-releasing factor systems of the rat hypothalamus. | The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20060401 |
Colchicine in experimental alkaline burns of the rat esophagus: an old drug, a new indication? | Pediatric surgery international 20060401 |
Change in the actin cytoskeleton during seismonastic movement of Mimosa pudica. | Plant & cell physiology 20060401 |
Contribution of Src-FAK signaling to the induction of connective tissue growth factor in renal fibroblasts. | Kidney international 20060401 |
D-Aspartate as a putative cell-cell signaling molecule in the Aplysia californica central nervous system. | Journal of neurochemistry 20060401 |
Febrile myalgia syndrome in familial Mediterranean fever. | Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20060401 |
Anti-inflammatory fibrosis suppression in threatened trabeculectomy bleb failure. | Archives of ophthalmology (Chicago, Ill. : 1960) 20060401 |
Involvement of cytoskeleton in AhR-dependent CYP1A1 expression. | Current drug metabolism 20060401 |
Aluminium chloride enhances colchicine production in root cultures of Gloriosa superba. | Biotechnology letters 20060401 |
Colchicine myoneuropathy in chronic renal failure patients with gout. | Nephrology (Carlton, Vic.) 20060401 |
Expression of corticosterone-binding globulin in the rat hypothalamus. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20060401 |
A novel LC-ESI-MS-MS method for sensitive quantification of colchicine in human plasma: application to two case reports. | Journal of analytical toxicology 20060401 |
Thiocolchicine-podophyllotoxin conjugates: dynamic libraries based on disulfide exchange reaction. | The Journal of organic chemistry 20060331 |
Colchicine antimitosis causes progression of S-(1,2-dichlorovinyl)-L-cysteine-induced injury leading to acute renal failure and death in mice. | Toxicology 20060315 |
Neuronal BC1 RNA: microtubule-dependent dendritic delivery. | Journal of molecular biology 20060310 |
Diabetic mice are protected from normally lethal nephrotoxicity of S-1,2-dichlorovinyl-L-cysteine (DCVC): role of nephrogenic tissue repair. | Toxicology and applied pharmacology 20060301 |
Newt orthologue of Growth arrest-specific 6 (NvGas6) is implicated in stress response during newt forelimb regeneration. | Developmental dynamics : an official publication of the American Association of Anatomists 20060301 |
A role for mixed lineage kinases in granule cell apoptosis induced by cytoskeletal disruption. | Journal of neurochemistry 20060301 |
Medication errors with the use of allopurinol and colchicine: a retrospective study of a national, anonymous Internet-accessible error reporting system. | The Journal of rheumatology 20060301 |
[Evaluation of the genotoxicity of vincristine and colchicine using mouse lymphoma tk mutation assay]. | Wei sheng yan jiu = Journal of hygiene research 20060301 |
A case of tuberculous meningoencephalitis in a patient with Behçet's disease. | Clinical rheumatology 20060201 |
99mTc-labeling of colchicine using [99mTc(CO)3(H2O)3]+ and [99mTc triple bond N]2+ core for the preparation of potential tumor-targeting agents. | Bioorganic & medicinal chemistry 20060201 |
Microtubule-dependent relocation of branchial V-H+-ATPase to the basolateral membrane in the Pacific spiny dogfish (Squalus acanthias): a role in base secretion. | The Journal of experimental biology 20060201 |
Gene-specific characterization of human histone H2B by electron capture dissociation. | Journal of proteome research 20060201 |
[Gout as an unusual cause of pelvic pain]. | Nederlands tijdschrift voor geneeskunde 20060121 |
Effect of drugs affecting microtubular assembly on microtubules, phospholipid synthesis and physiological indices (signalling, growth, motility and phagocytosis) in Tetrahymena pyriformis. | Cell biochemistry and function 20060101 |
Signaling via the angiotensin-converting enzyme results in the phosphorylation of the nonmuscle myosin heavy chain IIA. | Molecular pharmacology 20060101 |
Mechanical stretch-induced hypertrophy of neonatal rat ventricular myocytes is mediated by beta(1)-integrin-microtubule signaling pathways. | European journal of heart failure 20060101 |
Comparative study of respiratory burst induced by phorbol ester and zymosan in human granulocytes. | Clinical biochemistry 20060101 |
Distribution and chemical coding of corticotropin-releasing factor-immunoreactive neurons in the guinea pig enteric nervous system. | The Journal of comparative neurology 20060101 |
Familial mediterranean fever-related nephrotic syndrome and successful full-term pregnancy. | Archives of medical research 20060101 |
NPI-2358 is a tubulin-depolymerizing agent: in-vitro evidence for activity as a tumor vascular-disrupting agent. | Anti-cancer drugs 20060101 |
Cell adhesion regulates Ser/Thr phosphorylation and proteasomal degradation of HEF1. | Journal of cell science 20060101 |
Practical threshold for micronucleated reticulocyte induction observed for low doses of mitomycin C, Ara-C and colchicine. | Mutagenesis 20060101 |
Patterns of sequence loss and cytosine methylation within a population of newly resynthesized Brassica napus allopolyploids. | Plant physiology 20060101 |
Behçet's disease with unusual cutaneous lesions. | Journal of the European Academy of Dermatology and Venereology : JEADV 20060101 |
[Acute pericarditis: results of a survey of treatment practices of cardiologists]. | Archives des maladies du coeur et des vaisseaux 20060101 |
The effect of colchicine on the peritoneal membrane. | Renal failure 20060101 |
Therapy for recurrent acute pericarditis: a rheumatological solution? | Clinical and experimental rheumatology 20060101 |
Tubulin polymerization modulates interleukin-2 receptor signal transduction in human T cells. | Journal of receptor and signal transduction research 20060101 |
A role for the cytoskeleton in STAT5 activation in MCF7 human breast cancer cells stimulated with EGF. | The international journal of biochemistry & cell biology 20060101 |
Rhabdomyolysis in a patient treated with colchicine and atorvastatin. | The Annals of pharmacotherapy 20060101 |
Essential mixed cryoglobulinemia type II. | Clinical and experimental rheumatology 20060101 |
Advances in the management of gout and hyperuricaemia. | Scandinavian journal of rheumatology 20060101 |
Pharmacologic reductions of total tau levels; implications for the role of microtubule dynamics in regulating tau expression. | Molecular neurodegeneration 20060101 |
Microtubules regulate expression of ICAM-1 in epidermoid cells (KB cells). | Skin pharmacology and physiology 20060101 |
Pathophysiology, clinical presentation and treatment of gout. | Drugs 20060101 |
Etanercept in the treatment of arthritis in a patient with familial Mediterranean fever. | Clinical and experimental rheumatology 20060101 |
[Chemical signaling in plant microspore cells]. | Izvestiia Akademii nauk. Seriia biologicheskaia 20060101 |
Acute colchicine intoxication during clarithromycin administration in patients with chronic renal failure. | Journal of nephrology 20060101 |
An unusual cause of renal amyloidosis secondary to gout: the first description of familial occurrence. | Nucleosides, nucleotides & nucleic acids 20060101 |
Treatment options in colchicine resistant familial Mediterranean fever patients: thalidomide and etanercept as adjunctive agents. | Clinical and experimental rheumatology 20060101 |
Porcine reproductive and respiratory syndrome virus (PRRSV) infection spreads by cell-to-cell transfer in cultured MARC-145 cells, is dependent on an intact cytoskeleton, and is suppressed by drug-targeting of cell permissiveness to virus infection. | Virology journal 20060101 |
Primary cardiac amyloidosis with 20-year survival. | Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 20060101 |
In vitro polyploidisation in the family of the ranunculaceae. | Communications in agricultural and applied biological sciences 20060101 |
Colchicine in the treatment of the inflammatory phase of Graves' ophthalmopathy: a prospective and randomized trial with prednisone. | Arquivos brasileiros de oftalmologia 20060101 |
Topical therapy for actinic keratoses: current and evolving therapies. | Reviews on recent clinical trials 20060101 |
Primary biliary cirrhosis. | The New England journal of medicine 20051222 |
Patterns of hippocampal cell loss based on subregional lesions of the hippocampus. | Brain research 20051214 |
Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors. | Bioorganic & medicinal chemistry letters 20051201 |
Induction of resistance to Aplidin in a human ovarian cancer cell line related to MDR expression. | Cancer biology & therapy 20051201 |
Microtubules contribute to the birefringence of the retinal nerve fiber layer. | Investigative ophthalmology & visual science 20051201 |
New synthetic thiocolchicine derivatives as lowtoxic anticancer agents. | Archiv der Pharmazie 20051201 |
Localized amyloidosis: a survey of 35 French cases. | Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20051201 |
Colchicine and benzathine penicillin in the treatment of Behçet disease: a case comparative study. | Dermatology online journal 20051201 |
Microtubule disruptors and their interaction with biotransformation enzymes. | Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20051201 |
Cardiac troponins as biomarkers of drug- and toxin-induced cardiac toxicity and cardioprotection. | Expert opinion on drug metabolism & toxicology 20051201 |
Identification of novel and improved antimitotic agents derived from noscapine. | Journal of medicinal chemistry 20051117 |
Functional assessment of multiple P-glycoprotein (P-gp) probe substrates: influence of cell line and modulator concentration on P-gp activity. | Drug metabolism and disposition: the biological fate of chemicals 20051101 |
Effect of cytoskeleton disruptors on L-type Ca channel distribution in rat ventricular myocytes. | Cell calcium 20051101 |
An update on the treatment options for gout and calcium pyrophosphate deposition. | Expert opinion on pharmacotherapy 20051101 |
Understanding treatments for gout. | The American journal of managed care 20051101 |
Efforts directed toward the synthesis of colchicine: application of palladium-catalyzed siloxane cross-coupling methodology. | The Journal of organic chemistry 20051028 |
Disruption of the interaction of alpha-synuclein with microtubules enhances cell surface recruitment of the dopamine transporter. | Biochemistry 20051018 |
Okadaic acid: chromosomal non-disjunction analysis in human lymphocytes and study of aneugenic pathway in CHO-K1 cells. | Mutation research 20051015 |
The complement inhibitor, CRIT, undergoes clathrin-dependent endocytosis. | Experimental cell research 20051015 |
Synthesis and hepatic transport of strongly fluorescent cholephilic dipyrrinones. | The Journal of organic chemistry 20051014 |
Selective vulnerability of dopaminergic neurons to microtubule depolymerization. | The Journal of biological chemistry 20051007 |
N-PEP-12--a novel peptide compound that protects cortical neurons in culture against different age and disease associated lesions. | Journal of neural transmission (Vienna, Austria : 1996) 20051001 |
The role of the cytoskeleton in differentially regulating pressure-mediated effects on malignant colonocyte focal adhesion signaling and cell adhesion. | Carcinogenesis 20051001 |
Neuronal degeneration and iNOS expression in experimental brain contusion following treatment with colchicine, dexamethasone, tirilazad mesylate and nimodipine. | Acta neurochirurgica 20051001 |
Mutant tamm-horsfall glycoprotein accumulation in endoplasmic reticulum induces apoptosis reversed by colchicine and sodium 4-phenylbutyrate. | Journal of the American Society of Nephrology : JASN 20051001 |
Cell cycle-dependent localization and possible roles of the small GTPase Ran in mouse oocyte maturation, fertilization and early cleavage. | Reproduction (Cambridge, England) 20051001 |
Both microtubule-stabilizing and microtubule-destabilizing drugs inhibit hypoxia-inducible factor-1alpha accumulation and activity by disrupting microtubule function. | Cancer research 20051001 |
Acute renal failure associated with an accidental overdose of colchicine. | International journal of clinical pharmacology and therapeutics 20051001 |
Microtubular integrity differentially modifies the saturated and unsaturated fatty acid metabolism in cultured Hep G2 human hepatoma cells. | Lipids 20051001 |
Total synthesis of (-)-colchicine via a Rh-triggered cycloaddition cascade. | Organic letters 20050929 |
Colchicine in addition to conventional therapy for acute pericarditis: results of the COlchicine for acute PEricarditis (COPE) trial. | Circulation 20050927 |
Colchicine as first-choice therapy for recurrent pericarditis: results of the CORE (COlchicine for REcurrent pericarditis) trial. | Archives of internal medicine 20050926 |
A common pharmacophore for a diverse set of colchicine site inhibitors using a structure-based approach. | Journal of medicinal chemistry 20050922 |
Primary biliary cirrhosis. | The New England journal of medicine 20050922 |
Tetraparesis associated with colchicine is probably due to inhibition by verapamil of the P-glycoprotein efflux pump in the blood-brain barrier. | BMJ (Clinical research ed.) 20050917 |
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism. | Bioorganic & medicinal chemistry letters 20050915 |
Effectiveness of colchicine in a case of recurrent compressive rheumatoid pericarditis. | Rheumatology international 20050901 |
P-glycoprotein expression increases ATP release in respiratory cystic fibrosis cells. | Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 20050901 |
Assembly of GMPCPP-bound tubulin into helical ribbons and tubes and effect of colchicine. | Cell cycle (Georgetown, Tex.) 20050901 |
A case of non-specific interstitial pneumonia effectively treated with a combination of prednisolone and colchicine, in which granulation tissue was extensive. | Respirology (Carlton, Vic.) 20050901 |
A case of bilateral retinal vasculitis associated with Sweet syndrome. | Retina (Philadelphia, Pa.) 20050901 |
[A case report of acute neuromyopathy induced by concomitant use of colchicine and bezafibrate]. | No to shinkei = Brain and nerve 20050901 |
[Nephrogenic diabetes insipidus induced by colchicine--a case report]. | Polskie Archiwum Medycyny Wewnetrznej 20050901 |
Erythema nodosum leprosum and HIV infection: A therapeutic experience. | International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association 20050901 |
Biphasic kinetics of the colchicine-tubulin interaction: role of amino acids surrounding the A ring of bound colchicine molecule. | Biochemistry 20050802 |
Hyperhomocysteinemia in patients with Behçet's disease: is it due to inflammation or therapy? | Rheumatology international 20050801 |
Spontaneous renal laceration as the presenting feature of polyarteritis nodosa in a patient with familial Mediterranean fever after hepatitis A infection. | Rheumatology international 20050801 |
Growth factors mobilize multiple pools of KCa channels in developing parasympathetic neurons: role of ADP-ribosylation factors and related proteins. | Journal of neurophysiology 20050801 |
Adenosine deaminase enzyme levels, their relation with disease activity, and the effect of colchicine on adenosine deaminase levels in patients with Behçet's disease. | Rheumatology international 20050801 |
New developments in osteoarthritis. | Clinics in geriatric medicine 20050801 |
Evaluation of the neuronal apoptotic pathways involved in cytoskeletal disruption-induced apoptosis. | Biochemical pharmacology 20050801 |
Can colchicine potentiate the anticoagulant effect of fluindione? | European journal of clinical pharmacology 20050801 |
Fatal interaction between clarithromycin and colchicine in patients with renal insufficiency: a retrospective study. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050801 |
Evidence-based emergency medicine at the 'coal face'. | Emergency medicine Australasia : EMA 20050801 |
Antineoplastic agents. 515. Synthesis of human cancer cell growth inhibitors derived from 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene. | Journal of natural products 20050801 |
Caspase-independent apoptosis is activated by diazepam-induced mitotic failure in HeLa cells, but not in human primary fibroblasts. | Apoptosis : an international journal on programmed cell death 20050801 |
Two probable cases of serious drug interaction between clarithromycin and colchicine. | Southern medical journal 20050801 |
Chronic antidepressant treatment prevents accumulation of gsalpha in cholesterol-rich, cytoskeletal-associated, plasma membrane domains (lipid rafts). | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050701 |
Synthesis of selective SRPK-1 inhibitors: novel tricyclic quinoxaline derivatives. | Bioorganic & medicinal chemistry letters 20050701 |
Assessment of efficacy and psychomotor performances of thiocolchicoside and tizanidine in patients with acute low back pain. | International journal of clinical practice 20050701 |
Optimal management of chronic gout: attempting to render the (t)issues crystal-clear. | The New Zealand medical journal 20050624 |
Inhibition of mitosis by glycopeptide dendrimer conjugates of colchicine. | Chemistry (Weinheim an der Bergstrasse, Germany) 20050620 |
Involvement of actin in agonist-induced endocytosis of the G protein-coupled receptor for thromboxane A2: overcoming of actin disruption by arrestin-3 but not arrestin-2. | The Journal of biological chemistry 20050617 |
The effects of colchicine and hydroxychloroquine on the cyclo-oxygenases COX-1 and COX-2. | Rheumatology international 20050601 |
Calcium-containing crystals and osteoarthritis: implications for the clinician. | Current rheumatology reports 20050601 |
Familial Mediterranean fever protracted febrile myalgia in children: report of two cases. | Rheumatology international 20050601 |
[Effects of anther--pretreatments on the survival percentage of isolated microspores of maize]. | Shi yan sheng wu xue bao 20050601 |
Colchicine treatment differently affects releasable thyrotropin-releasing hormone (TRH) pools in the hypothalamic paraventricular nucleus (PVN) and the median eminence (ME). | Cellular and molecular neurobiology 20050601 |
Two novel series of allocolchicinoids with modified seven membered B-rings: design, synthesis, inhibition of tubulin assembly and cytotoxicity. | Bioorganic & medicinal chemistry 20050516 |
Fatal colchicine poisoning by accidental ingestion of meadow saffron-case report. | Forensic science international 20050510 |
Selective serotonin reuptake inhibitors in familial Mediterranean fever: are we treating depression or inflammation? | Rheumatology international 20050501 |
Influence of Ca2+-binding proteins and the cytoskeleton on Ca2+-dependent inactivation of high-voltage activated Ca2+ currents in thalamocortical relay neurons. | Pflugers Archiv : European journal of physiology 20050501 |
Giardia lamblia: evaluation of the in vitro effects of nocodazole and colchicine on trophozoites. | Experimental parasitology 20050501 |
Colchicine decreases airway hyperreactivity after phosgene exposure. | Inhalation toxicology 20050501 |
Secretin activation of the apical Na+-dependent bile acid transporter is associated with cholehepatic shunting in rats. | Hepatology (Baltimore, Md.) 20050501 |
Colchicine and 2-methoxyestradiol Inhibit Human Angiogenesis. | The Journal of surgical research 20050501 |
Resolution of liver fibrosis in chronic CCl4 administration in the rat after discontinuation of treatment: effect of silymarin, silibinin, colchicine and trimethylcolchicinic acid. | Basic & clinical pharmacology & toxicology 20050501 |
Chromosomal aberrations in lymphocytes of healthy subjects and risk of cancer. | Environmental health perspectives 20050501 |
Comparison of colchicine, dapsone, triamcinolone, and diphenhydramine therapy for the treatment of brown recluse spider envenomation: a double-blind, controlled study in a rabbit model. | Archives of dermatology 20050501 |
Parkin stabilizes microtubules through strong binding mediated by three independent domains. | The Journal of biological chemistry 20050429 |
Discovery of S-phase arresting agents derived from noscapine. | Journal of medicinal chemistry 20050421 |
Colchicine for alcoholic and non-alcoholic liver fibrosis and cirrhosis. | The Cochrane database of systematic reviews 20050418 |
Microtubule disruption suppresses allergic response through the inhibition of calcium influx in the mast cell degranulation pathway. | Journal of immunology (Baltimore, Md. : 1950) 20050415 |
Determination of colchicine residues in sheep serum and milk using high-performance liquid chromatography combined with electrospray ionization ion trap tandem mass spectrometry. | Analytical chemistry 20050415 |
[Hyperuricemia/gout. Main symptoms of arthropathy. Severe acute joint pain, redness, inflammation]. | Praxis 20050406 |
Establishment and characterization of new cellular lymphoma model expressing transgenic human MDR1. | Leukemia research 20050401 |
[Acute coronary syndrome after diclofenac induced coronary spasm]. | Zeitschrift fur Kardiologie 20050401 |
Potential antagonism of tubulin-binding anticancer agents in combination therapies. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050401 |
Colchicine treatment of alcoholic cirrhosis: a randomized, placebo-controlled clinical trial of patient survival. | Gastroenterology 20050401 |
A-432411, a novel indolinone compound that disrupts spindle pole formation and inhibits human cancer cell growth. | Molecular cancer therapeutics 20050401 |
An unusual case of diarrhoea. | Australian family physician 20050401 |
Striatal expression of GDNF and differential vulnerability of midbrain dopaminergic cells. | The European journal of neuroscience 20050401 |
Monozygotic twins concordant for intestinal Behçet's disease. | Journal of gastroenterology 20050401 |
The basolateral NHE1 Na+/H+ exchanger regulates transepithelial HCO3- absorption through actin cytoskeleton remodeling in renal thick ascending limb. | The Journal of biological chemistry 20050325 |
-NH-dansyl isocolchicine exhibits a significantly improved tubulin-binding affinity and microtubule inhibition in comparison to isocolchicine by binding tubulin through its A and B rings. | Biochemistry 20050308 |
Akt activation is necessary for growth factor-induced trafficking of functional K(Ca) channels in developing parasympathetic neurons. | Journal of neurophysiology 20050301 |
Evaluation of a chylomicron flow blocking approach to investigate the intestinal lymphatic transport of lipophilic drugs. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050301 |
Protracted fever of unknown origin as the presenting symptom of Behçet's disease. Report of a case. | Joint, bone, spine : revue du rhumatisme 20050301 |
CXCR2 Expression on neutrophils is upregulated during the relapsing phase of ocular Behcet disease. | Current eye research 20050301 |
Small-cell lung cancer (human): potentiation of endocytic membrane activity by voltage-gated Na(+) channel expression in vitro. | The Journal of membrane biology 20050301 |
Methanogenic symbionts of anaerobic ciliates and their contribution to methanogenesis in an anoxic rice field soil. | FEMS microbiology ecology 20050301 |
Adenomatous polyposis coli influences micronuclei induction by PhIP and acrylamide in mouse erythrocytes. | Mutation research 20050207 |
Role of microtubules in estradiol-17beta-D-glucuronide-induced alteration of canalicular Mrp2 localization and activity. | American journal of physiology. Gastrointestinal and liver physiology 20050201 |
Disruption of microtubular network attenuates histamine-induced dilation in rat mesenteric vessels. | American journal of physiology. Cell physiology 20050201 |
Disruption of microtubules leads to glucocorticoid receptor degradation in HeLa cell line. | Cellular signalling 20050201 |
New colchicinoids from a native Jordanian meadow saffron, colchicum brachyphyllum: isolation of the first naturally occurring dextrorotatory colchicinoid. | Journal of natural products 20050201 |
Remission of recalcitrant epidermolysis bullosa acquisita (EBA) with colchicine monotherapy. | The Journal of dermatology 20050201 |
Characterization of aurora-a in porcine oocytes and early embryos implies its functional roles in the regulation of meiotic maturation, fertilization and cleavage. | Zygote (Cambridge, England) 20050201 |
Participation of the ubiquitin-proteasome pathway in rat oocyte activation. | Zygote (Cambridge, England) 20050201 |
The dileucine motif at the COOH terminus of human multidrug resistance P-glycoprotein is important for folding but not activity. | The Journal of biological chemistry 20050128 |
Quantitative structure-activity relationship (5D-QSAR) study of combretastatin-like analogues as inhibitors of tubulin assembly. | Journal of medicinal chemistry 20050127 |
Sulfonamide drugs binding to the colchicine site of tubulin: thermodynamic analysis of the drug-tubulin interactions by isothermal titration calorimetry. | Journal of medicinal chemistry 20050127 |
Tubulin-polymerization inhibitors derived from thalidomide. | Bioorganic & medicinal chemistry letters 20050117 |
Antitumor agents. Part 236: Synthesis of water-soluble colchicine derivatives. | Bioorganic & medicinal chemistry letters 20050103 |
Involvement of the cytoskeleton in oxytocin secretion by cultured bovine luteal cells. | Biology of reproduction 20050101 |
Thiocolchicine dimers: a novel class of topoisomerase-I inhibitors. | Biochemical pharmacology 20050101 |
Clinical and immunological effects of azithromycin in Behçet's disease. | Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20050101 |
[Reversible lower limb lymphedema as the first manifestation of cutaneous periarteritis nodosa]. | La Revue de medecine interne 20050101 |
Evidence in favour of a role for peripheral-type benzodiazepine receptor ligands in amplification of neuronal apoptosis. | Apoptosis : an international journal on programmed cell death 20050101 |
Reversal of cirrhosis in a patient with primary biliary cirrhosis-autoimmune hepatitis overlap syndrome. | Digestive diseases and sciences 20050101 |
Targeting microtubules for cancer chemotherapy. | Current medicinal chemistry. Anti-cancer agents 20050101 |
The chemistry and biology of antimitotic chalcones and related enone systems. | Current pharmaceutical design 20050101 |
Acute myopathy in a patient with concomitant use of pravastatin and colchicine. | The Annals of pharmacotherapy 20050101 |
Possible colchicine rhabdomyolysis in a fluvastatin-treated patient. | The Annals of pharmacotherapy 20050101 |
Circadian and light regulation of oxytocin and parvalbumin protein levels in the ciliated ependymal layer of the third ventricle in the C57 mouse. | Neuroscience 20050101 |
Implication of cyclin-dependent kinase 5 in the neuroprotective properties of lithium. | Neuroscience 20050101 |
[Contractile proteins in chemical signal transduction in plant microspores]. | Izvestiia Akademii nauk. Seriia biologicheskaia 20050101 |
Three clinical problems: weird thyroid function tests, difficult gout, and dementia. | Clinical medicine (London, England) 20050101 |
The effects of drug delivery via hydrophilic acrylic (hydrogel) intraocular lens systems on the epithelial cells in culture. | Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye 20050101 |
Superior vena cava thrombosis and chylothorax in a young patient. | Clinical and experimental rheumatology 20050101 |
Actinic keratoses, basal cell carcinoma, and squamous cell carcinoma: uncommon treatments. | Clinics in dermatology 20050101 |
Anticholinesterase efficiency of some tropolone alkaloids and their lumiderivatives. | Doklady. Biochemistry and biophysics 20050101 |
Treatment of refractory seizures due to a benign mass present in the corpus callosum with an ion magnetic inductor: case report. | Brain tumor pathology 20050101 |
Linking alterations in tau phosphorylation and cleavage during neuronal apoptosis. | The Journal of biological chemistry 20041224 |
Distribution of methionine and leucine enkephalin neurons within the social behavior circuitry of the male Syrian hamster brain. | Brain research 20041224 |
RLIP76 (RALBP1)-mediated transport of leukotriene C4 (LTC4) in cancer cells: implications in drug resistance. | International journal of cancer 20041220 |
Arylthioindoles, potent inhibitors of tubulin polymerization. | Journal of medicinal chemistry 20041202 |
Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 1. Structure-activity relationships of the 4-aryl group. | Journal of medicinal chemistry 20041202 |
Analysis of ATP-binding cassette transporter expression in drug-selected cell lines by a microarray dedicated to multidrug resistance. | Molecular pharmacology 20041201 |
Cytoskeletal myotoxicity from simvastatin and colchicine. | Muscle & nerve 20041201 |
Presence of cytoskeleton proteins in parotid glands and their roles during secretion. | Archives of oral biology 20041201 |
Acute colchicine intoxication during clarithromycin administration. | The Annals of pharmacotherapy 20041201 |
Colchicine for prophylaxis of acute flares when initiating allopurinol for chronic gouty arthritis. | The Journal of rheumatology 20041201 |
Colchicine myotoxicity: case reports and literature review. | Pharmacotherapy 20041201 |
Akt up-regulation increases resistance to microtubule-directed chemotherapeutic agents through mammalian target of rapamycin. | Molecular cancer therapeutics 20041201 |
(+/-)-huprine Y, (-)-huperzine A and tacrine do not show neuroprotective properties in an apoptotic model of neuronal cytoskeletal alteration. | Journal of Alzheimer's disease : JAD 20041201 |
[Pulmonary arterial aneurysms in Behçet's syndrome. Report of 4 cases]. | Archives des maladies du coeur et des vaisseaux 20041201 |
Transient differentiation of adult human bone marrow cells into neuron-like cells in culture: development of morphological and biochemical traits is mediated by different molecular mechanisms. | Stem cells and development 20041201 |
Microtubule disarray in primary cultures of human hepatocytes inhibits transcriptional activity of the glucocorticoid receptor via activation of c-jun N-terminal kinase. | Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20041201 |
N-formyl-Met-Leu-Phe-induced oxidative burst in DMSO-differentiated HL-60 cells requires active Hsp90, but not intact microtubules. | Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20041201 |
Mechanisms involved in the blood-brain barrier increased permeability induced by Phoneutria nigriventer spider venom in rats. | Brain research 20041119 |
The B-ring substituent at C-7 of colchicine and the alpha-C-terminus of tubulin communicate through the 'tail-body' interaction. | Proteins 20041115 |
Prolonged cytotoxic effect of colchicine released from biodegradable microspheres. | Journal of biomedical materials research. Part B, Applied biomaterials 20041115 |
Role of microtubules in ischemic preconditioning against myocardial infarction. | Cardiovascular research 20041101 |
Characterization of subpopulations of neurons producing melanin-concentrating hormone in the rat ventral diencephalon. | Journal of neurochemistry 20041101 |
Contraction augments L-type Ca2+ currents in adherent guinea-pig cardiomyocytes. | The Journal of physiology 20041015 |
Microtubule-interfering activity of parthenolide. | Chemico-biological interactions 20041015 |
Computational comparison of microtubule-stabilising agents laulimalide and peloruside with taxol and colchicine. | Bioorganic & medicinal chemistry letters 20041004 |
Effect of chemical enhancers and iontophoresis on thiocolchicoside permeation across rabbit and human skin in vitro. | Journal of pharmaceutical sciences 20041001 |
[Mucosal epidermolysis bullosa acquisita complicated by laryngeal stenosis]. | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20041001 |
Polyploidisation of metastatic colon carcinoma cells by microtubule and tubulin interacting drugs: effect on proteolytic activity and invasiveness. | International journal of oncology 20041001 |
Celastraceae sesquiterpenes as a new class of modulators that bind specifically to human P-glycoprotein and reverse cellular multidrug resistance. | Cancer research 20041001 |
[Experimental study on Sorbaria sorbifolia extract against chronic liver damage in rats]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20041001 |
The drug-binding pocket of the human multidrug resistance P-glycoprotein is accessible to the aqueous medium. | Biochemistry 20040928 |
RhoA/ROCK and Cdc42 regulate cell-cell contact and N-cadherin protein level during neurodetermination of P19 embryonal stem cells. | Journal of neurobiology 20040905 |
Influence of irrigation solutions combined with colchicine and diclofenac sodium on articular cartilage in a rat model. | Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA 20040901 |
Fate of the first polar bodies in mouse oocytes. | Molecular reproduction and development 20040901 |
Managing refractory uraemic pericarditis with colchicine. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040901 |
Effects of colchicine on the maximum biliary excretion of cholephilic compounds in rats. | Journal of gastroenterology and hepatology 20040901 |
Cell spreading controls balance of prestress by microtubules and extracellular matrix. | Frontiers in bioscience : a journal and virtual library 20040901 |
[Amyloidosis in adult onset Still's disease]. | La Revue de medecine interne 20040901 |
Coronin 7, the mammalian POD-1 homologue, localizes to the Golgi apparatus. | FEBS letters 20040827 |
Microtubule structure and its stabilisation. | Organic & biomolecular chemistry 20040807 |
Gout: a review of its aetiology and treatment. | Hong Kong medical journal = Xianggang yi xue za zhi 20040801 |
Invasion of epithelial mammalian cells by Paracoccidioides brasiliensis leads to cytoskeletal rearrangement and apoptosis of the host cell. | Microbes and infection 20040801 |
New metabolic and pharmacokinetic characteristics of thiocolchicoside and its active metabolite in healthy humans. | Fundamental & clinical pharmacology 20040801 |
In situ transport of vinblastine and selected P-glycoprotein substrates: implications for drug-drug interactions at the mouse blood-brain barrier. | Pharmaceutical research 20040801 |
Oxaline, a fungal alkaloid, arrests the cell cycle in M phase by inhibition of tubulin polymerization. | Biochimica et biophysica acta 20040723 |
Stereochemical variations on the colchicine motif. Peracid oxidation of thiocolchicone. Synthesis, conformation and inhibition of microtubule assembly. | Organic & biomolecular chemistry 20040721 |
Colchicine poisoning: case report of two suicides. | Forensic science international 20040716 |
Sequence divergence of Entamoeba histolytica tubulin is responsible for its altered tertiary structure. | Biochemical and biophysical research communications 20040702 |
Shared apical sorting of anion exchanger isoforms AE2a, AE2b1, and AE2b2 in primary hepatocytes. | Biochemical and biophysical research communications 20040702 |
BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo. | Cancer research 20040701 |
Antiangiogenic and antitumoral activity of phenyl-3-(2-chloroethyl)ureas: a class of soft alkylating agents disrupting microtubules that are unaffected by cell adhesion-mediated drug resistance. | Cancer research 20040701 |
Evaluation of the colchicine-like activity of Gloriosa superba-extracted fractions for mosquito (Diptera: Culicidae) cytogenetic study. | Journal of medical entomology 20040701 |
Total syntheses of colchicine in comparison: a journey through 50 years of synthetic organic chemistry. | Angewandte Chemie (International ed. in English) 20040621 |
[Abdominal pain and recurrent cholestatic jaundice]. | Praxis 20040609 |
Chemical identity of 5-HT2A receptor immunoreactive neurons of the rat septal complex and dorsal hippocampus. | Brain research 20040604 |
Autonomic regulation of calcium and potassium channels is oppositely modulated by microtubules in cardiac myocytes. | American journal of physiology. Heart and circulatory physiology 20040601 |
Antimitotic antifungal compound benomyl inhibits brain microtubule polymerization and dynamics and cancer cell proliferation at mitosis, by binding to a novel site in tubulin. | Biochemistry 20040601 |
Synthesis and antileukemic activity of new 3-(5-methylisoxazol-3-yl) and 3-(pyrimidin-2-yl)-2-styrylquinazolin-4(3H)-ones. | Farmaco (Societa chimica italiana : 1989) 20040601 |
Behcet's disease and its oral manifestations. | Dentistry today 20040601 |
Effect of colchicine on cyclosporine nephrotoxicity, reduction of TGF-beta overexpression, apoptosis, and oxidative damage: an experimental animal study. | Transplantation proceedings 20040601 |
Th1 cytokine pattern (IL-12 and IL-18) in bronchoalveolar lavage fluid (BALF) before and after treatment with interferon gamma-1b (IFN-gamma-1b) or colchicine in patients with idiopathic pulmonary fibrosis (IPF/UIP). | Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG 20040601 |
Is the songbird Area X striatal, pallidal, or both? An anatomical study. | The Journal of comparative neurology 20040531 |
Synthesis and structure-activity relationships of 3-aminobenzophenones as antimitotic agents. | Journal of medicinal chemistry 20040520 |
6-phosphogluconate dehydrogenase and glucose-6-phosphate dehydrogenase form a supramolecular complex in human neutrophils that undergoes retrograde trafficking during pregnancy. | Journal of immunology (Baltimore, Md. : 1950) 20040515 |
Effect of short-term morphine exposure on P-glycoprotein expression and activity in cancer cell lines. | Oncology reports 20040501 |
Establishment of a P-glycoprotein substrate screening model and its preliminary application. | World journal of gastroenterology 20040501 |
Taxol activates inducible nitric oxide synthase in rat astrocytes: the role of MAP kinases and NF-kappaB. | Cellular and molecular life sciences : CMLS 20040501 |
Chemical constituents from the mangrove plant, Aegiceras corniculatum. | Journal of natural products 20040501 |
[Amyloidosis]. | Nihon rinsho. Japanese journal of clinical medicine 20040501 |
Myelodysplasia and acute myeloid leukaemia in a case of rheumatoid arthritis with secondary amyloidosis treated with chlorambucil. | The Journal of the Association of Physicians of India 20040501 |
Therapeutic challenges in gout. | The New Zealand medical journal 20040423 |
Expression of integrin beta1 and its roles on adhesion between different cell cycle hepatocellular carcinoma cells (SMMC-7721) and human umbilical vein endothelial cells. | Colloids and surfaces. B, Biointerfaces 20040415 |
Improved energy coupling of human P-glycoprotein by the glycine 185 to valine mutation. | Biochemistry 20040406 |
Lithium prevents colchicine-induced apoptosis in rat cerebellar granule neurons. | Bipolar disorders 20040401 |
Review article: current management of alcoholic liver disease. | Alimentary pharmacology & therapeutics 20040401 |
Microtubules as a target for anticancer drugs. | Nature reviews. Cancer 20040401 |
Alterations of the M6p/Igf2 receptor gene in hepatocellular carcinomas induced by N-nitrosodiethylamine and a choline-deficient L-amino acid-defined diet in rats. | Molecular carcinogenesis 20040401 |
A randomized controlled trial of colchicine plus ursodiol versus methotrexate plus ursodiol in primary biliary cirrhosis: ten-year results. | Hepatology (Baltimore, Md.) 20040401 |
Uptake of [111In-DTPA0]octreotide in the rat kidney is inhibited by colchicine and not by fructose. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20040401 |
Different spindle checkpoint proteins monitor microtubule attachment and tension at kinetochores in Drosophila cells. | Journal of cell science 20040401 |
Spontaneous retinal activity modulates BDNF trafficking in the developing chick visual system. | Molecular and cellular neurosciences 20040401 |
Secretin: hypothalamic distribution and hypothesized neuroregulatory role in autism. | Cellular and molecular neurobiology 20040401 |
Acute poisoning with autumn crocus (Colchicum autumnale L.). | Wiener klinische Wochenschrift 20040331 |
The use of a dendrimer-propranolol prodrug to bypass efflux transporters and enhance oral bioavailability. | Journal of controlled release : official journal of the Controlled Release Society 20040324 |
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies. | Biochemical and biophysical research communications 20040319 |
Determination of four sequential stages during microautophagy in vitro. | The Journal of biological chemistry 20040312 |
Exocytosis of a complement component C3-like protein by tunicate hemocytes. | Developmental and comparative immunology 20040301 |
Therapy for immunoglobulin light chain amyloidosis: the new and the old. | Blood reviews 20040301 |
Tritrichomonas foetus pseudocysts adhere to vaginal epithelial cells in a contact-dependent manner. | Parasitology research 20040301 |
Flavonoid permeability across an in situ model of the blood-brain barrier. | Free radical biology & medicine 20040301 |
Cell cycle activation linked to neuronal cell death initiated by DNA damage. | Neuron 20040219 |
New concepts of the pathogenesis of alcoholic liver disease lead to novel treatments. | Current gastroenterology reports 20040201 |
Glycogen synthase kinase-3 regulates cytoskeleton and translocation of Rac1 in long cellular extensions of human keratinocytes. | Experimental cell research 20040201 |
Severe respiratory muscle weakness related to long-term colchicine therapy. | Respiratory care 20040201 |
Effects of positive and negative lens treatment on retinal and choroidal glucagon and glucagon receptor mRNA levels in the chicken. | Investigative ophthalmology & visual science 20040201 |
Systemic anti-inflammatory fibrosis suppression in threatened trabeculectomy failure. | Clinical & experimental ophthalmology 20040201 |
Cyclosporin A enhances colchicine-induced apoptosis in rat cerebellar granule neurons. | British journal of pharmacology 20040201 |
Synthesis and biological evaluation of paclitaxel-thiocolchicine hybrids. | Chemistry & biodiversity 20040201 |
Non-redundant role of Shc in Erk activation by cytoskeletal reorganization. | The Journal of biological chemistry 20040130 |
A role for the cytoskeleton in prolactin-dependent mammary epithelial cell differentiation. | Journal of cell science 20040115 |
Effects of colchicine on liver functions of cirrhotic rats: beneficial effects result from stellate cell inactivation and inhibition of TGF beta1 expression. | Chemico-biological interactions 20040115 |
In vivo dynamics of the rough deal checkpoint protein during Drosophila mitosis. | Current biology : CB 20040106 |
Role of potassium channels, the sodium-potassium pump and the cytoskeleton in the control of dog sperm volume. | Theriogenology 20040101 |
The role of the cytoskeleton in the viscoelastic properties of human articular chondrocytes. | Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20040101 |
The effect of drugs on cell structure of Tritrichomonas foetus. | Parasitology research 20040101 |
Preantral follicle culture as a novel in vitro assay in reproductive toxicology testing in mammalian oocytes. | Mutagenesis 20040101 |
The management of Peyronie's disease. | BJU international 20040101 |
Effect of cyanidin 3-O-beta-glucopyranoside on micronucleus induction in cultured human lymphocytes by four different mutagens. | Environmental and molecular mutagenesis 20040101 |
Ionizing radiation sensitizes bone cells to apoptosis. | Bone 20040101 |
Neutrophil adhesion molecule expression in familial Mediterranean fever: discordance between the intravascular regulation of beta2 integrin and L-selectin expression in acute attack. | Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20040101 |
Gout: a clinical and radiologic review. | Radiologic clinics of North America 20040101 |
Use of ultrasound biomicroscopy, indocyanine green angiography and HLA-B51 testing as adjunct methods in the appraisal of Behçet's uveitis. | International ophthalmology 20040101 |
Colchicine for primary biliary cirrhosis. | The Cochrane database of systematic reviews 20040101 |
Differential contributions of dorsal hippocampal subregions to memory acquisition and retrieval in contextual fear-conditioning. | Hippocampus 20040101 |
[Gout--clinical characteristics and physical therapy]. | Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury 20040101 |
Apoptosis in Hep2 cells treated with etoposide and colchicine. | Cancer detection and prevention 20040101 |
[Neurotoxic effects of medications: an update]. | Revue medicale de Liege 20040101 |
Unloaded shortening velocity in single permeabilized vascular smooth muscle cells is independent of microtubule status. | Journal of muscle research and cell motility 20040101 |
Distribution and origin of vesicular glutamate transporter 2-immunoreactive fibers in the rat hippocampus. | Hippocampus 20040101 |
Management of acute and chronic gouty arthritis: present state-of-the-art. | Drugs 20040101 |
Therapeutic approaches to familial Mediterranean fever. What do we know and where are we going to? | Clinical and experimental rheumatology 20040101 |
Changes in physicochemical properties of microtubules lead to the formation of a single spherical structure of mitochondrial assembly enveloping nuclear chromatins. | Journal of electron microscopy 20040101 |
Improvement of transfection efficiency of epithelioma papulosum cyprini carp cells by modification of cell cycle and use of an optimal promoter. | Marine biotechnology (New York, N.Y.) 20040101 |
Transition state analysis of the coupling of drug transport to ATP hydrolysis by P-glycoprotein. | The Journal of biological chemistry 20031226 |
Methanethiosulfonate derivatives of rhodamine and verapamil activate human P-glycoprotein at different sites. | The Journal of biological chemistry 20031212 |
Steric vs hydrogen-bonding control of atropisomerization: preparation of either diastereomer of configurationally stable allocolchicinoids. | The Journal of organic chemistry 20031212 |
Exposure of bovine oocytes to the endogenous metabolite 2-methoxyestradiol during in vitro maturation inhibits early embryonic development. | Biology of reproduction 20031201 |
Colchicine-induced myopathy in a teenager with familial Mediterranean fever. | The Annals of pharmacotherapy 20031201 |
Colchicine-induced rhabdomyolysis in a patient with chronic heart failure. | Acta cardiologica 20031201 |
Behçet's disease with relapsing cutaneous polyarteritis-nodosa-like lesions, responsive to oral cyclosporine therapy. | Dermatology online journal 20031201 |
Photoaffinity labeling under non-energized conditions of a specific drug-binding site of the ABC multidrug transporter LmrA from Lactococcus lactis. | Biochemical and biophysical research communications 20031121 |
Modulation of the expression of connective tissue growth factor by alterations of the cytoskeleton. | The Journal of biological chemistry 20031107 |
Resveratrol analog (Z)-3,5,4'-trimethoxystilbene is a potent anti-mitotic drug inhibiting tubulin polymerization. | International journal of cancer 20031101 |
Expression of BDNF mRNA in substantia nigra is dependent on target integrity and independent of neuronal activation. | Journal of neurochemistry 20031101 |
Extended delivery of the antimitotic agent colchicine from thermoresponsive N-isopropylacrylamide-based copolymer films to human vascular smooth muscle cells. | Journal of biomedical materials research. Part A 20031101 |
Case report. Hepatic portal venous gas: transient radiographic finding associated with colchicine toxicity. | The British journal of radiology 20031101 |
The compliance-questionnaire-rheumatology compared with electronic medication event monitoring: a validation study. | The Journal of rheumatology 20031101 |
Clinical profile and treatment outcome of livedoid vasculitis: a case series. | Annals of the Academy of Medicine, Singapore 20031101 |
Clinical practice. Gout. | The New England journal of medicine 20031023 |
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 33-2003. A 37-year-old man with a history of alcohol and drug abuse and sudden onset of leg weakness. | The New England journal of medicine 20031023 |
CALEB/NGC interacts with the Golgi-associated protein PIST. | The Journal of biological chemistry 20031010 |
Disruption of microtubules in rat skeletal muscle does not inhibit insulin- or contraction-stimulated glucose transport. | American journal of physiology. Endocrinology and metabolism 20031001 |
Neuroprotective action of flavopiridol, a cyclin-dependent kinase inhibitor, in colchicine-induced apoptosis. | Neuropharmacology 20031001 |
Focal and secondarily generalised convulsive status epilepticus induced by thiocolchicoside in the rat. | Seizure 20031001 |
Review of current nonsurgical management of Peyronie's disease. | International journal of impotence research 20031001 |
In vivo saturation of the transport of vinblastine and colchicine by P-glycoprotein at the rat blood-brain barrier. | Pharmaceutical research 20031001 |
Extrinsic regulation of injury/growth-related gene expression in the inferior olive of the adult rat. | The European journal of neuroscience 20031001 |
[Aphthae and aphthosis]. | Revue de stomatologie et de chirurgie maxillo-faciale 20031001 |
Seven cDNAs enriched following hippocampal lesion: possible roles in neuronal responses to injury. | Brain research. Molecular brain research 20030910 |
Cytoarchitecture and efferent projections of the nucleus incertus of the rat. | The Journal of comparative neurology 20030908 |
Tautomeric selectivity towards colchicinoids in the tosylation of colchiceine on a heterogeneous, easily removable catalyst. | Organic & biomolecular chemistry 20030907 |
[Treatment of primary biliary cirrhosis]. | Orvosi hetilap 20030907 |
G beta gamma mediates the interplay between tubulin dimers and microtubules in the modulation of Gq signaling. | The Journal of biological chemistry 20030905 |
Uptake of histamine by mouse peritoneal macrophages and a macrophage cell line, RAW264.7. | American journal of physiology. Cell physiology 20030901 |
Erosive arthritis in a patient with Behçet's disease. | Rheumatology international 20030901 |
Dolastatin 15 binds in the vinca domain of tubulin as demonstrated by Hummel-Dreyer chromatography. | European journal of biochemistry 20030901 |
Colchicine-induced myopathy with myotonia in a patient with chronic renal failure. | Clinical neurology and neurosurgery 20030901 |
c-Fos and peptide immunoreactivities in the central extended amygdala of morphine-dependent rats after naloxone-precipitated withdrawal. | The European journal of neuroscience 20030901 |
Activation of PPAR-alpha in streptozotocin-induced diabetes is essential for resistance against acetaminophen toxicity. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030901 |
Multicenter, randomized, double-blinded, placebo-controlled trial of thiocolchicoside in acute low back pain. | Joint, bone, spine : revue du rhumatisme 20030901 |
Characterization of all the subunits of replication factor C from a higher plant, rice (Oryza sativa L.), and their relation to development. | Plant molecular biology 20030901 |
Colchicine myopathy in a patient with familial Mediterranean fever and normal renal function. | Arthritis and rheumatism 20030815 |
Colchicine-induced rhabdomyolysis: the whole is greater than the sum of its parts! | The American journal of medicine 20030815 |
Mechanisms by which cAMP increases bile acid secretion in rat liver and canalicular membrane vesicles. | American journal of physiology. Gastrointestinal and liver physiology 20030801 |
Advances in alcoholic liver disease. | Best practice & research. Clinical gastroenterology 20030801 |
Efficiency of colchicine and corticosteroids in a leg ulceration with cholesterol embolism in a woman with rheumatoid arthritis. | Rheumatology (Oxford, England) 20030801 |
Protein kinase C activation downregulates human organic anion transporter 1-mediated transport through carrier internalization. | Journal of the American Society of Nephrology : JASN 20030801 |
Fibrosis and glycogen stores depletion induced by prolonged biliary obstruction in the rat are ameliorated by metadoxine. | Liver international : official journal of the International Association for the Study of the Liver 20030801 |
Polymerization and calcium binding of the tubulin-colchicine complex in the GDP state. | Bioscience, biotechnology, and biochemistry 20030801 |
Novel benzylidene-9(10H)-anthracenones as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization. | Journal of medicinal chemistry 20030717 |
Improvement of hepatocyte-specific gene expression by a targeted colchicine prodrug. | Chembiochem : a European journal of chemical biology 20030707 |
Microtubule-dependent PKC-alpha localization in A7r5 smooth muscle cells. | American journal of physiology. Cell physiology 20030701 |
Histamine potentiates IP(3)-mediated Ca(2+) release via thapsigargin-sensitive Ca(2+) pumps. | Cellular signalling 20030701 |
Distinct chaperone mechanisms can delay the formation of aggresomes by the myopathy-causing R120G alphaB-crystallin mutant. | Human molecular genetics 20030701 |
Colchicine down-regulates cytochrome P450 2B6, 2C8, 2C9, and 3A4 in human hepatocytes by affecting their glucocorticoid receptor-mediated regulation. | Molecular pharmacology 20030701 |
The antimitotic effect of the neem terpenoid azadirachtin on cultured insect cells. | Insect biochemistry and molecular biology 20030701 |
Fos induction in the rat deep cerebellar and vestibular nuclei following central administration of colchicine: a qualitative and quantitative time-course study. | Brain research bulletin 20030630 |
Astrocyte stellation induced by Rho kinase inhibitors in culture. | Brain research. Developmental brain research 20030612 |
Temperature dependence of fluid phase endocytosis coincides with membrane properties of pig platelets. | Biochimica et biophysica acta 20030610 |
Permanent activation of the human P-glycoprotein by covalent modification of a residue in the drug-binding site. | The Journal of biological chemistry 20030606 |
Discovery of substituted N-phenyl nicotinamides as potent inducers of apoptosis using a cell- and caspase-based high throughput screening assay. | Journal of medicinal chemistry 20030605 |
Gout. | JAMA 20030604 |
Peptides that regulate food intake: orexin gene expression is increased during states of hypertriglyceridemia. | American journal of physiology. Regulatory, integrative and comparative physiology 20030601 |
cAMP-dependent activation of the renal-specific Na+-K+-2Cl- cotransporter is mediated by regulation of cotransporter trafficking. | American journal of physiology. Renal physiology 20030601 |
Type 1 diabetic mice are protected from acetaminophen hepatotoxicity. | Toxicological sciences : an official journal of the Society of Toxicology 20030601 |
Determination of thiocolchicoside in its binary mixtures (thiocolchicoside-glafenine and thiocolchicoside-floctafenine) by TLC-densitometry. | Farmaco (Societa chimica italiana : 1989) 20030601 |
The effects of dentate granule cell destruction on behavioral activity and Fos protein expression induced by systemic MDMA in rats. | Neuroscience research 20030601 |
Distribution and chemical coding of cocaine- and amphetamine-regulated transcript peptide (CART)-immunoreactive neurons in the guinea pig bowel. | Cell and tissue research 20030601 |
Glucagon induces the plasma membrane insertion of functional aquaporin-8 water channels in isolated rat hepatocytes. | Hepatology (Baltimore, Md.) 20030601 |
Diagnosis of renal and hepatic cyst infections by 18-F-fluorodeoxyglucose positron emission tomography in autosomal dominant polycystic kidney disease. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20030601 |
Epidermal growth factor and insulin short-term increase hPepT1-mediated glycylsarcosine uptake in Caco-2 cells. | Acta physiologica Scandinavica 20030601 |
Restorative potential of cholinergic rich transplants in cholchicine induced lesioned rats: a comparative study of single and multiple micro-transplantation approach. | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20030601 |
Exocytotic 'constipation' is a mechanism of tubulin/lysosomal interaction in colchicine myopathy. | Experimental cell research 20030501 |
Microtubule-dependent transport of secretory vesicles in RBL-2H3 cells. | Traffic (Copenhagen, Denmark) 20030501 |
Induction of apoptosis in estrogen dependent and independent breast cancer cells by the marine terpenoid dehydrothyrsiferol. | Biochemical pharmacology 20030501 |
Plasma thrombomodulin levels in patients with Behçet's disease. | Rheumatology international 20030501 |
Thrombotic thrombocytopenic purpura in a patient with Behçet's disease. | Arthritis and rheumatism 20030501 |
Topical therapy for actinic keratoses, II: Diclofenac, colchicine, and retinoids. | Cutis 20030501 |
The role of the cytoskeleton in mechanotransduction in human osteoblast-like cells. | Human & experimental toxicology 20030501 |
Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery. | Journal of medicinal chemistry 20030424 |
Substrate-induced conformational changes in the transmembrane segments of human P-glycoprotein. Direct evidence for the substrate-induced fit mechanism for drug binding. | The Journal of biological chemistry 20030418 |
Streptozotocin-induced diabetic mice are resistant to lethal effects of thioacetamide hepatotoxicity. | Toxicology and applied pharmacology 20030415 |
Parkin binds to alpha/beta tubulin and increases their ubiquitination and degradation. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030415 |
Novel B-ring modified allocolchicinoids of the NCME series: design, synthesis, antimicrotubule activity and cytotoxicity. | Bioorganic & medicinal chemistry 20030403 |
Colchicine attenuates left ventricular hypertrophy but preserves cardiac function of aortic-constricted rats. | Journal of applied physiology (Bethesda, Md. : 1985) 20030401 |
Combined treatment with vitamin E and colchicine in the early stages of Peyronie's disease. | BJU international 20030401 |
Microtubules are required for cytokeratin aggresome (Mallory body) formation in hepatocytes: an in vitro study. | Experimental and molecular pathology 20030401 |
Estradiol and testosterone have opposite effects on microtubule polymerization. | Neuroendocrinology 20030401 |
Differential effects of colchicine on central dopaminergic neuronal activity and prolactin secretion in estrogen-primed ovariectomized rats. | The Chinese journal of physiology 20030331 |
Microtubule-disruption-induced and chemotactic-peptide-induced migration of human neutrophils: implications for differential sets of signalling pathways. | Journal of cell science 20030301 |
Biological activity of A-289099: an orally active tubulin-binding indolyloxazoline derivative. | Molecular cancer therapeutics 20030301 |
Microtubule disruption utilizes an NFkappa B-dependent pathway to stabilize HIF-1alpha protein. | The Journal of biological chemistry 20030227 |
Colchicine induces apoptosis in organotypic hippocampal slice cultures. | Brain research 20030227 |
Concerning the chemical nature of tubulin subunits that cap and stabilize microtubules. | Biochemistry 20030225 |
Unique developmental patterns of GABAergic neurons in rat spinal cord. | The Journal of comparative neurology 20030203 |
Severe colchicine-macrolide interactions. | Prescrire international 20030201 |
Microtubules mobility affects the modulation of L-type I(Ca) by muscarinic and beta-adrenergic agonists in guinea-pig cardiac myocytes. | Journal of molecular and cellular cardiology 20030201 |
Diagnosis and management of hepatic copper accumulation in a Skye terrier. | The Journal of small animal practice 20030201 |
[A case of Behçet's disease associated with neuromyopathy induced by combination therapy with colchicine and cyclosporin]. | Ryumachi. [Rheumatism] 20030201 |
Distribution of glutamic acid decarboxylase, neurotensin, enkephalin, neuropeptide Y, and cholecystokinin neurons in the septo-preoptic region of male rats. | The Journal of reproduction and development 20030201 |
[The association of polyarteritis nodosa and familial Mediterranean fever]. | Presse medicale (Paris, France : 1983) 20030111 |
Buccal delivery of thiocolchicoside: in vitro and in vivo permeation studies. | International journal of pharmaceutics 20030102 |
Efficacy of colchicine in patients with primary biliary cirrhosis poorly responsive to ursodiol and methotrexate. | The American journal of gastroenterology 20030101 |
Modulation of endotoxin-induced endothelial activity by microtubule depolymerization. | The Journal of trauma 20030101 |
Etoposide and merbarone are clastogenic and aneugenic in the mouse bone marrow micronucleus test complemented by fluorescence in situ hybridization with the mouse minor satellite DNA probe. | Environmental and molecular mutagenesis 20030101 |
[Gouty arthritis]. | Nihon rinsho. Japanese journal of clinical medicine 20030101 |
Expression of a splice variant of choline acetyltransferase in magnocellular neurons of the tuberomammillary nucleus of rat. | Neuroscience 20030101 |
Poly(N-isopropylacrylamide) co-polymer films as potential vehicles for delivery of an antimitotic agent to vascular smooth muscle cells. | Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 20030101 |
Efficacy of high-dose intravenous immunoglobulins in two patients with idiopathic recurrent pericarditis refractory to previous immunosuppressive treatment. | Italian heart journal : official journal of the Italian Federation of Cardiology 20030101 |
[Treatment of cholestatic liver diseases]. | Duodecim; laaketieteellinen aikakauskirja 20030101 |
Organization of the endoplasmic reticulum in dividing cells of the gymnosperms Pinus brutia and Pinus nigra, and of the pterophyte Asplenium nidus. | Cell biology international 20030101 |
[Effects of cycloheximide, aminoglutethimide, indomethacin, cytochalasin B and colchicine on ovulation and the ultrastructure of the ovarian follicle wall in the stellate sturgeon Acipenser stellatus Pall]. | Ontogenez 20030101 |
Differential effects of stretch and compression on membrane currents and [Na+]c in ventricular myocytes. | Progress in biophysics and molecular biology 20030101 |
Pyoderma gangrenosum associated with sarcoidosis. | Acta dermato-venereologica 20030101 |
Supercritical carbon dioxide extraction of colchicine and related alkaloids from seeds of Colchicum autumnale L. | Phytochemical analysis : PCA 20030101 |
[Erythroid differentiation of K562 cells resistant to 2-(4'-dimethylaminostyryl)quinoline 1-oxide or 4-nitroquinoline 1-oxide is significantly increased after thymidine treatment]. | Izvestiia Akademii nauk. Seriia biologicheskaia 20030101 |
Role of microfilaments and microtubules in the invasion of INT-407 cells by Campylobacter jejuni. | Microbiology and immunology 20030101 |
Immunomodulatory agents for idiopathic pulmonary fibrosis. | The Cochrane database of systematic reviews 20030101 |
Pentoxifylline use for Behçet's disease. The result of a survey among rheumatologists in North America. | Advances in experimental medicine and biology 20030101 |
The vascular targeting agent combretastatin A-4-phosphate induces neutrophil recruitment to endothelial cells in vitro. | Anticancer research 20030101 |
The activity of antioxidant enzymes in Arabidopsis thaliana exposed to colchicine and H2O2. | Cellular & molecular biology letters 20030101 |
[Behçet's disease]. | Annales de dermatologie et de venereologie 20030101 |
Risks versus benefits of NSAIDs including aspirin in myocarditis: a review of the evidence from animal studies. | Drug safety 20030101 |
Mechanosensing and signal transduction in tendrils. | Advances in space research : the official journal of the Committee on Space Research (COSPAR) 20030101 |
Pregnancy alters glucose-6-phosphate dehydrogenase trafficking, cell metabolism, and oxidant release of maternal neutrophils. | The Journal of clinical investigation 20021215 |
Colchicine-induced myopathy with normal creatine phosphokinase level in a renal transplant patient. | Nephron 20021201 |
Postoperative fibrosis suppression. | The British journal of ophthalmology 20021201 |
Anti-inflammatory fibrosis suppression in threatened trabeculectomy bleb failure produces good long term control of intraocular pressure without risk of sight threatening complications. | The British journal of ophthalmology 20021201 |
Changes in the arginine-vasopressin immunoreactive systems in male mice lacking a functional aromatase gene. | Journal of neuroendocrinology 20021201 |
The stability of cortical microtubules depends on their orientation. | The Plant journal : for cell and molecular biology 20021201 |
VMN/LHA functional inhibition in tumor-bearing rats suggests hypothalamic involvement in cancer anorexia. | Nutritional neuroscience 20021201 |
Effects of isoprenoid analogues of SDB-ethylenediamine on multidrug resistant tumor cells alone and in combination with chemotherapeutic drugs. | Journal of medicinal chemistry 20021121 |
Nocodazole-induced p53-dependent c-Jun N-terminal kinase activation reduces apoptosis in human colon carcinoma HCT116 cells. | The Journal of biological chemistry 20021115 |
Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein 1. | The Journal of biological chemistry 20021115 |
Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20021115 |
Exogenous growth factors stimulate the regeneration of ganglion cells in the chicken retina. | Developmental biology 20021115 |
Synthesis and mechanism of action of novel pyrimidinyl pyrazole derivatives possessing antiproliferative activity. | Bioorganic & medicinal chemistry letters 20021104 |
Reorganization and translocation of the ectoplasmic cytoskeleton in the leech zygote by condensation of cytasters and interactions of dynamic microtubules and actin filaments. | Cell motility and the cytoskeleton 20021101 |
Rhabdomyolysis associated with gemfibrozil-colchicine therapy. | The Annals of pharmacotherapy 20021101 |
Detrimental effects of cyclosporin A on long-term graft survival in familial Mediterranean fever renal allograft recipients: experience of two transplantation centers. | The Israel Medical Association journal : IMAJ 20021101 |
Physicochemical compatibility between thiocolchicoside injections (Miotens) and pharmaceutical products frequently used for combined therapy. | Farmaco (Societa chimica italiana : 1989) 20021101 |
Effects of thiocolchicine on axonal cytoskeleton of the rat peroneus nerve. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20021101 |
[Behcet's disease therapy review]. | Anales de medicina interna (Madrid, Spain : 1984) 20021101 |
Campylobacter fetus adheres to and enters INT 407 cells. | Canadian journal of microbiology 20021101 |
Vehicle effects on in vitro skin permeation of thiocolchicoside. | Die Pharmazie 20021101 |
Perturbation of microtubule polymerization by quercetin through tubulin binding: a novel mechanism of its antiproliferative activity. | Biochemistry 20021029 |
Antitumor agents. Part 215: antitubulin effects of cytotoxic B-ring modified allocolchicinoids. | Bioorganic & medicinal chemistry letters 20021021 |
Germanium oxide inhibits the transition from G2 to M phase of CHO cells. | Chemico-biological interactions 20021020 |
[Treatment of pulmonary fibrosis]. | Presse medicale (Paris, France : 1983) 20021019 |
Caveolin-1 phosphorylation in human squamous and epidermoid carcinoma cells: dependence on ErbB1 expression and Src activation. | Experimental cell research 20021015 |
Edwardsiella ictaluri invasion of IEC-6, Henle 407, fathead minnow and channel catfish enteric epithelial cells. | Diseases of aquatic organisms 20021004 |
Enhanced production of itaconic acid from corn starch and market refuse fruits by genetically manipulated Aspergillus terreus SKR10. | Bioresource technology 20021001 |
Intracerebroventricular administration of colchicine produces cognitive impairment associated with oxidative stress in rats. | Pharmacology, biochemistry, and behavior 20021001 |
Colchicine suppresses osteopontin expression and inflammatory cell infiltration in chronic cyclosporine nephrotoxicity. | Nephron 20021001 |
Apparent elastic modulus and hysteresis of skeletal muscle cells throughout differentiation. | American journal of physiology. Cell physiology 20021001 |
Meiotic telomere clustering is inhibited by colchicine but does not require cytoplasmic microtubules. | Journal of cell science 20021001 |
Index of suspicion. | Pediatrics in review 20021001 |
Inhibition of in vitro attachment of Giardia trophozoites by mucin. | The Journal of parasitology 20021001 |
Oral therapy for Peyronie's disease. | International journal of impotence research 20021001 |
Numerical chromosomal aberrations in the early life-history stages of a marine tubeworm, Pomatoceros lamarckii (Polychaeta: Serpulidae). | Aquatic toxicology (Amsterdam, Netherlands) 20020924 |
Studies on a high encapsulation of colchicine by a niosome system. | International journal of pharmaceutics 20020905 |
Trophoblast differentiation modulates the activity of caspases in primary cultures of term human trophoblasts. | Pediatric research 20020901 |
Characterization of nuclear betaII-tubulin in tumor cells: a possible novel target for taxol. | Cell motility and the cytoskeleton 20020901 |
Microtubules of the mouse testis exhibit differential sensitivity to the microtubule disruptors Carbendazim and colchicine. | Toxicological sciences : an official journal of the Society of Toxicology 20020901 |
Application of LC-MS analysis to a colchicine fatality. | Journal of analytical toxicology 20020901 |
Natural and induced polyploidy in Acacia dealbata Link. and Acacia mangium Willd. | Annals of botany 20020901 |
Two parallel pathways mediate cytoplasmic localization of the dioxin (aryl hydrocarbon) receptor. | The Journal of biological chemistry 20020830 |
Microtubule involvement in the adaptation to altered mechanical load in developing chick myocardium. | Circulation research 20020823 |
MEK/ERK pathway mediates cell-shape-dependent plasminogen activator inhibitor type 1 gene expression upon drug-induced disruption of the microfilament and microtubule networks. | Journal of cell science 20020801 |
Anti-/pro-oxidant effects of phenolic compounds in cells: are colchicine metabolites chain-breaking antioxidants? | Toxicology 20020801 |
Long-term suppression of chronic Sweet's syndrome with colchicine. | Journal of the American Academy of Dermatology 20020801 |
Ultrafine particles cause cytoskeletal dysfunctions in macrophages. | Toxicology and applied pharmacology 20020801 |
Hyperuricemia and gout: a reign of complacency. | Cleveland Clinic journal of medicine 20020801 |
Hyperosmotic stress induces formation of tubulin macrotubules in root-tip cells of Triticum turgidum: their probable involvement in protoplast volume control. | Plant & cell physiology 20020801 |
Enhanced antitumor activity of irofulven in combination with antimitotic agents. | Investigational new drugs 20020801 |
Cytoskeleton, passive tension and the contraction of the rat aorta to phorbol 12,13-dibutyrate. | Pharmacological research 20020801 |
Could nicotine be beneficial for Behçet's disease? | Clinical rheumatology 20020801 |
Presenilin-binding protein forms aggresomes in monkey kidney COS-7 cells. | Journal of neurochemistry 20020801 |
Chronic hyperosmolality enhances ANP-dependent cGMP production via stimulation of transcription and protein synthesis in cultured rat IMCD cells. | The Tohoku journal of experimental medicine 20020801 |
Induction of aneuploidy in male mouse germ cells detected by the sperm-FISH assay: a review of the present data base. | Mutation research 20020725 |
G(1) and G(2) cell-cycle arrest following microtubule depolymerization in human breast cancer cells. | The Journal of clinical investigation 20020701 |
2-Alkoxycarbonylaminopyridines: inhibitors of Mycobacterium tuberculosis FtsZ. | The Journal of antimicrobial chemotherapy 20020701 |
A case of Behçet's disease with pulmonary arterial aneurysm and secondary amyloidosis. | Rheumatology (Oxford, England) 20020701 |
Colchicine myoneuropathy in a renal transplant patient. | Transplant international : official journal of the European Society for Organ Transplantation 20020701 |
Renal amyloidosis in a pentazocine addict. | The Journal of the Association of Physicians of India 20020701 |
[Myopathy caused by colchicine with myotonia]. | Revista de neurologia 20020701 |
The Arctic Alzheimer mutation enhances sensitivity to toxic stress in human neuroblastoma cells. | Neuroscience letters 20020621 |
CAS/CSE 1 stimulates E-cadhrin-dependent cell polarity in HT-29 human colon epithelial cells. | Biochemical and biophysical research communications 20020621 |
Functional analysis of MRP1 cloned from bovine. | FEBS letters 20020619 |
A randomized controlled trial to evaluate the slow-acting symptom-modifying effects of colchicine in osteoarthritis of the knee: a preliminary report. | Arthritis and rheumatism 20020615 |
Stereoselectivity of the benzannulation reaction: efficient central-to-axial chirality transfer. | Journal of the American Chemical Society 20020612 |
Synthesis and structure-activity relationship of 2-aminobenzophenone derivatives as antimitotic agents. | Journal of medicinal chemistry 20020606 |
One-pot synthesis of benzo[b]furan and indole inhibitors of tubulin polymerization. | Journal of medicinal chemistry 20020606 |
Synthesis and antimicrotubule activity of combretatropone derivatives. | Bioorganic & medicinal chemistry 20020601 |
Mechanisms through which ammonia regulates cortical collecting duct net proton secretion. | American journal of physiology. Renal physiology 20020601 |
Comparative effect of colchicine and colchiceine on cytotoxicity and CYP gene expression in primary human hepatocytes. | Toxicology in vitro : an international journal published in association with BIBRA 20020601 |
Dopamine-induced inhibition of Na+-K+-ATPase activity requires integrity of actin cytoskeleton in opossum kidney cells. | Acta physiologica Scandinavica 20020601 |
Colchicine decreases apoptotic cell death in chronic cyclosporine nephrotoxicity. | The Journal of laboratory and clinical medicine 20020601 |
Cardiac microtubules are more resistant to chemical depolymerisation in streptozotocin-induced diabetes in the rat. | Pflugers Archiv : European journal of physiology 20020601 |
Cytoskeleton disruption causes apoptotic degeneration of dentate granule cells in hippocampal slice cultures. | Neuropharmacology 20020601 |
Effects of phosphorylation and cytoskeleton-affecting reagents on GABA(A) receptor recruitment into synaptosomes following acute stress. | Pharmacology, biochemistry, and behavior 20020601 |
Colchicine-induced rhabdomyolysis. | The Annals of pharmacotherapy 20020501 |
Late diagnosis of severe colchicine intoxication. | Pediatrics 20020501 |
Invasion of HeLa cells by Enterococcus faecalis clinical isolates. | Medical microbiology and immunology 20020501 |
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
Epithelial cell mitotic arrest--a useful postmortem histologic marker in cases of possible colchicine toxicity. | Forensic science international 20020418 |
Gap junctions assemble in the presence of cytoskeletal inhibitors, but enhanced assembly requires microtubules. | Experimental cell research 20020415 |
Calyculin A-induced endothelial cell shape changes are independent of [Ca(2+)](i) elevation and may involve actin polymerization. | Biochimica et biophysica acta 20020403 |
Role of the cytoskeleton in mediating effect of vasopressin and herbimycin A on secretory K channels in CCD. | American journal of physiology. Renal physiology 20020401 |
The mutual regulation of arginine-vasopressin and PTHrP secretion in dissociated supraoptic neurons. | Endocrinology 20020401 |
NHE3 and NHERF are targeted to the basolateral membrane in proximal tubules of colchicine-treated rats. | Kidney international 20020401 |
Sodium current modulation by a tubulin/GTP coupled process in rat neonatal cardiac myocytes. | The Journal of physiology 20020401 |
Nitric oxide production by a murine macrophage cell line (RAW264.7) stimulated with lipopolysaccharide from Actinobacillus actinomycetemcomitans. | Oral microbiology and immunology 20020401 |
Missing the point! | Veterinary and human toxicology 20020401 |
Of liver, whisky and plants: a requiem for colchicine in alcoholic cirrhosis? | European journal of gastroenterology & hepatology 20020401 |
Lack of effect of colchicine in alcoholic cirrhosis: final results of a double blind randomized trial. | European journal of gastroenterology & hepatology 20020401 |
Enhancement of transgene expression by combining glucocorticoids and anti-mitotic agents during transient transfection using DNA-cationic liposomes. | Molecular therapy : the journal of the American Society of Gene Therapy 20020401 |
A randomized controlled trial to evaluate the slow-acting symptom modifying effects of a regimen containing colchicine in a subset of patients with osteoarthritis of the knee. | Osteoarthritis and cartilage 20020401 |
Treatment of alcoholic hepatitis. | Journal of gastroenterology and hepatology 20020401 |
Induction of nephrotoxic serum nephritis in inbred mice and suppressive effect of colchicine on the development of this nephritis. | Pharmacological research 20020401 |
Highly specific and sensitive liquid chromatography-tandem mass spectrometry method for the determination of 3-desmethylthiocolchicine in human plasma as analyte for the assessment of bioequivalence after oral administration of thiocolchicoside. | Journal of chromatography. A 20020308 |
Improvement of combination chemotherapy tolerance by introduction of polycistronic retroviral vector drug resistance genes MGMT and MDR1 into human umbilical cord blood CD34+ cells. | Leukemia research 20020301 |
Disruption of microtubules uncouples budding and nuclear division in Toxoplasma gondii. | Journal of cell science 20020301 |
Retrograde repression of growth-associated protein-43 mRNA expression in rat cortical neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020301 |
Microtubule depolymerization facilitates contraction of rat aorta via activation of Rho-kinase. | Vascular pharmacology 20020301 |
Application of the palladium-catalyzed borylation/Suzuki coupling (BSC) reaction to the synthesis of biologically active biaryl lactams. | The Journal of organic chemistry 20020222 |
[Summary of the Dutch College of General Practitioners' 'Gout' Standard]. | Nederlands tijdschrift voor geneeskunde 20020216 |
Mechanosensitive ion channels in cultured sensory neurons of neonatal rats. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020215 |
Inhibition of tubulin polymerization by vitilevuamide, a bicyclic marine peptide, at a site distinct from colchicine, the vinca alkaloids, and dolastatin 10. | Biochemical pharmacology 20020215 |
Synthesis and biological evaluation of 2-indolyloxazolines as a new class of tubulin polymerization inhibitors. Discovery of A-289099 as an orally active antitumor agent. | Bioorganic & medicinal chemistry letters 20020211 |
Colchicine and indomethacin for the treatment of relapsing polychondritis. | Journal of the American Academy of Dermatology 20020201 |
Colchicine myopathy: a vacuolar myopathy with selective type I muscle fiber involvement. An immunohistochemical and electron microscopic study of two cases. | Acta neuropathologica 20020201 |
[Hyperuricemia and gout. Case report]. | Deutsche medizinische Wochenschrift (1946) 20020201 |
[Hyperuricemia and gout--treatment]. | Deutsche medizinische Wochenschrift (1946) 20020201 |
Cytoskeletal inhibitors, anti-adhesion molecule antibodies, and lectins inhibit hepatocyte spheroid formation. | Acta medica Okayama 20020201 |
In vitro-packaged SV40 pseudovirions as highly efficient vectors for gene transfer. | Human gene therapy 20020120 |
The proline-rich domain of p53 is required for cooperation with anti-neoplastic agents to promote apoptosis of tumor cells. | Oncogene 20020103 |
P-gp-induced modulation of regulatory volume increase occurs via PKC in mouse proximal tubule. | American journal of physiology. Renal physiology 20020101 |
In vitro and in vivo activity of LS 4477 and LS 4559, novel analogues of the tubulin binder estramustine. | European journal of cancer (Oxford, England : 1990) 20020101 |
The single laser flow cytometric micronucleus test: a time course study using colchicine and urethane in rat and mouse peripheral blood and acetaldehyde in rat peripheral blood. | Mutagenesis 20020101 |
Glycine receptors involved in synaptic transmission are selectively regulated by the cytoskeleton in mouse spinal neurons. | Journal of neurophysiology 20020101 |
Effect of colchicine and cytokines on MEFV expression and C5a inhibitor activity in human primary fibroblast cultures. | The Israel Medical Association journal : IMAJ 20020101 |
Involvement of microtubule integrity in memory impairment caused by colchicine. | Pharmacology, biochemistry, and behavior 20020101 |
Neuroprotection and aging of the cholinergic system: a role for the ergoline derivative nicergoline (Sermion). | Neuroscience 20020101 |
Optic nerve involvement in neuro-Behcet's disease. | Japanese journal of ophthalmology 20020101 |
Ankylosing spondylitis and Behçet's disease in combination. Two case reports. | Joint, bone, spine : revue du rhumatisme 20020101 |
Developing a model of colchicine neuropathy. | Microsurgery 20020101 |
Is it gout? Tap the joint! | Journal of the Medical Association of Georgia 20020101 |
Imaging of P glycoprotein function in vivo with PET. | Novartis Foundation symposium 20020101 |
Differential regulation of P-glycoprotein genes in primary rat hepatocytes by collagen sandwich and drugs. | Journal of cellular biochemistry 20020101 |
1,25(OH)2-vitamin D3 induces translocation of the vitamin D receptor (VDR) to the plasma membrane in skeletal muscle cells. | Journal of cellular biochemistry 20020101 |
Regionally selective neurotoxicity of NMDA and colchicine is independent of hippocampal neural circuitry. | Neuroscience 20020101 |
Activation of capsaicin receptors on the sciatic nerve induces FOS expression in the spinal dorsal horn of adult rats. | Neuro-Signals 20020101 |
Host-parasite interactions in Staphylococcus aureus keratitis. | DNA and cell biology 20020101 |
Mechanisms of colchicine effect in the treatment of asbestosis and idiopathic pulmonary fibrosis. | Lung 20020101 |
Current therapy for Behçet's disease. | American journal of therapeutics 20020101 |
Roles of the cytoskeleton and of protein phosphorylation events in the osmotic stress response in eel intestinal epithelium. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20020101 |
Colchicine neuromyopathy: a report of six cases. | Clinical and experimental rheumatology 20020101 |
Successful treatment of familial Mediterranean fever attacks with thalidomide in a colchicine resistant patient. | Clinical and experimental rheumatology 20020101 |
Evaluation of the aneugenic potential of the fungicide Ferbam in mice. | Teratogenesis, carcinogenesis, and mutagenesis 20020101 |
Improvement of the bioavailability of colchicine in rats by co-administration of D-alpha-tocopherol polyethylene glycol 1000 succinate and a polyethoxylated derivative of 12-hydroxy-stearic acid. | Arzneimittel-Forschung 20020101 |
Colchicine-induced acute myopathy in a patient with concomitant use of simvastatin. | Clinical neuropharmacology 20020101 |
P-glycoprotein expression by cancer cells affects cell cytotoxicity and cell-cycle perturbations induced by six chemotherapeutic drugs. | Journal of experimental therapeutics & oncology 20020101 |
In vitro permeation screening of a new formulation of thiocolchicoside containing various enhancers. | Drug delivery 20020101 |
Abstracts of the Fourth International Symposium on Molecular Insect Science. May 28-June 2, 2002. Tucson, Arizona, USA. | Journal of insect science (Online) 20020101 |
Are POMC neurons targets for sex steroids in the arcuate nucleus of the rat? | Neuroreport 20011221 |
Synthetic 2-aroylindole derivatives as a new class of potent tubulin-inhibitory, antimitotic agents. | Journal of medicinal chemistry 20011220 |
Hereditary periodic fever. | The New England journal of medicine 20011213 |
New antimitotic agents with activity in multi-drug-resistant cell lines and in vivo efficacy in murine tumor models. | Journal of medicinal chemistry 20011206 |
Estrogens modulate experimentally induced apoptosis of granule cells in the adult hippocampus. | The Journal of comparative neurology 20011203 |
Regulation of the nitric oxide synthase-nitric oxide-cGMP pathway in rat mesenteric endothelial cells. | Journal of applied physiology (Bethesda, Md. : 1985) 20011201 |
The effects of dentate granule cell destruction on behavioural activity and Fos protein expression induced by systemic methamphetamine in rats. | British journal of pharmacology 20011201 |
The clinical trials in the initial five-year award period of the Asthma Clinical Research Network. | Controlled clinical trials 20011201 |
Recruitment strategies in the Asthma Clinical Research Network. | Controlled clinical trials 20011201 |
Selective modulation of P-glycoprotein-mediated drug resistance. | British journal of cancer 20011201 |
Decreased expression of Bcl-x protein during hepatocarcinogenesis induced exogenously and endogenously in rats. | Japanese journal of cancer research : Gann 20011201 |
Current studies on anti-endotoxic chemical components of traditional Chinese medicine in China. | Acta pharmacologica Sinica 20011201 |
Danggui shaoyao san improve colchichine-induced learning acquisition impairment in rats. | Acta pharmacologica Sinica 20011201 |
[Is chronic or recurrent idiopathic pericarditis an autonomous inflammatory disease?]. | La Revue de medecine interne 20011201 |
Verapamil sensitisation to alkaloids on colchicine-selected human colon adenocarcinoma cells. | Journal of physiology and biochemistry 20011201 |
The microtubule cytoskeleton participates in control of beta2 integrin avidity. | The Journal of biological chemistry 20011130 |
PepT1-mediated epithelial transport of dipeptides and cephalexin is enhanced by luminal leptin in the small intestine. | The Journal of clinical investigation 20011115 |
Involvement of TLCK-sensitive serine protease in colchicine-induced cell death of sympathetic neurons in culture. | Journal of neuroscience research 20011115 |
Microtubule cytoskeleton perturbation induced by taxol and colchicine affects chaperonin containing TCP-1 (CCT) subunit gene expression in Tetrahymena cells. | Biochimica et biophysica acta 20011111 |
Antitumor Agents. 211. Fluorinated 2-phenyl-4-quinolone derivatives as antimitotic antitumor agents. | Journal of medicinal chemistry 20011108 |
Effect of short-term cyclic stretch on sodium pump activity in aortic smooth muscle cells. | American journal of physiology. Heart and circulatory physiology 20011101 |
Beta amyloid peptide (Abeta42) is internalized via the G-protein-coupled receptor FPRL1 and forms fibrillar aggregates in macrophages. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011101 |
Effects of the membrane dipole potential on the interaction of saquinavir with phospholipid membranes and plasma membrane receptors of Caco-2 cells. | The Journal of biological chemistry 20011019 |
Cytoskeleton elements mediate the inhibition of the (Na++K+)atpase activity by PKC in Rhodnius prolixus malpighian tubules during hyperosmotic shock. | Archives of insect biochemistry and physiology 20011001 |
Antifibrotic therapy for the treatment of pulmonary fibrosis. | The American journal of the medical sciences 20011001 |
Axon terminals containing tyrosine hydroxylase- and dopamine-beta-hydroxylase immunoreactivity form synapses with galanin immunoreactive neurons in the lateral division of the bed nucleus of the stria terminalis in the rat. | Brain research 20010928 |
The synthesis and tubulin binding activity of thiophene-based analogues of combretastatin A-4. | Bioorganic & medicinal chemistry letters 20010903 |
Physiochemical aspects of tubulin-interacting antimitotic drugs. | Current pharmaceutical design 20010901 |
Type 1 diabetes leads to cytoskeleton changes that are reflected in insulin action on rat cardiac K(+) currents. | American journal of physiology. Endocrinology and metabolism 20010901 |
Regulation of PGE(2) and PGI(2) release from human umbilical vein endothelial cells by actin cytoskeleton. | American journal of physiology. Cell physiology 20010901 |
Modulation of endogenous beta-tubulin isotype expression as a result of human beta(III)cDNA transfection into prostate carcinoma cells. | British journal of cancer 20010901 |
Ten-year combination treatment with colchicine and ursodeoxycholic acid for primary biliary cirrhosis: a double-blind, placebo-controlled trial on symptomatic patients. | Alimentary pharmacology & therapeutics 20010901 |
Discovery of a novel compound: insight into mechanisms for acrylamide-induced axonopathy and colchicine-induced apoptotic neuronal cell death. | Brain research 20010803 |
Increased CO(2) stimulates K/Rb reabsorption mediated by H-K-ATPase in CCD of potassium-restricted rabbit. | American journal of physiology. Renal physiology 20010801 |
A comparison of allergen and polycation induced cutaneous responses in the rabbit. | British journal of pharmacology 20010801 |
Absence of androgen receptor in the growth hormone releasing hormone-containing neurones in the rat mediobasal hypothalamus. | Journal of neuroendocrinology 20010801 |
Reversing effect of agosterol A, a spongean sterol acetate, on multidrug resistance in human carcinoma cells. | Japanese journal of cancer research : Gann 20010801 |
The inhibitory effects of colchicine on cell proliferation and mineralisation in culture. | The Journal of bone and joint surgery. British volume 20010801 |
Epileptic seizures after treatment with thiocolchicoside. | Epilepsia 20010801 |
Uptake of Malassezia furfur by human dermal fibroblasts: effect of ketoconazole and cytoskeleton inhibitors. | Archives of dermatological research 20010801 |
Detection of disulfide bonds in bovine brain tubulin and their role in protein folding and microtubule assembly in vitro: a novel disulfide detection approach. | Biochemistry 20010731 |
A-204197, a new tubulin-binding agent with antimitotic activity in tumor cell lines resistant to known microtubule inhibitors. | Cancer research 20010715 |
Production of proinflammatory cytokines by resident tissue macrophages after phagocytosis of apoptotic cells. | Cellular immunology 20010710 |
Reversal of drug resistance mediated by multidrug resistance protein (MRP) 1 by dual effects of agosterol A on MRP1 function. | International journal of cancer 20010701 |
Colchicine for persistent constipation after total abdominal colectomy with ileorectostomy for colonic inertia. | Journal of clinical gastroenterology 20010701 |
Enhancement of the T-type calcium current by hyposmotic shock in isolated guinea-pig ventricular myocytes. | Journal of molecular and cellular cardiology 20010701 |
Micronuclei and other nuclear lesions as genotoxicity indicators in rainbow trout Oncorhynchus mykiss. | Ecotoxicology and environmental safety 20010701 |
Mechanically induced potentials in rat atrial fibroblasts depend on actin and tubulin polymerisation. | Pflugers Archiv : European journal of physiology 20010701 |
Gout, bradycardia, and hypercholesterolemia after renal transplantation. | Southern medical journal 20010701 |
Spindle poisons induce allelic loss in mouse lymphoma cells through mitotic non-disjunction. | Mutation research 20010627 |
Colchicine inhibits taurodeoxycholate transport in pericentral but not in periportal hepatocytes. | Biochimica et biophysica acta 20010620 |
Studies about the mechanism of internalization by mammary epithelial cells of Escherichia coli isolated from persistent bovine mastitis. | Veterinary microbiology 20010606 |
Structure-activity relationships of phenylcyclohexene and biphenyl antitubulin compounds against plant and mammalian cells. | Bioorganic & medicinal chemistry letters 20010604 |
Reduction of telomerase activity in human liver cancer cells by a histone deacetylase inhibitor. | Journal of cellular physiology 20010601 |
Regulation by retinoic acid of acylation-stimulating protein and complement C3 in human adipocytes. | The Biochemical journal 20010601 |
Microtubule depolymerization in rat seminiferous epithelium is associated with diminished tyrosination of alpha-tubulin. | Biology of reproduction 20010601 |
Hypertonic activation of the renal betaine/GABA transporter is microtubule dependent. | Kidney international 20010601 |
Autoradiographic localization of [3H]thiocolchicoside binding sites in the rat brain and spinal cord. | Neuropharmacology 20010601 |
Dose-dependent conjugation of sulfobromophthalein and hepatic transit time in bile fistula rats: role of the microtubule-dependent vesicle pathway. | Digestive diseases and sciences 20010601 |
Pervilleine A, a novel tropane alkaloid that reverses the multidrug-resistance phenotype. | Cancer research 20010515 |
Long-term outcomes after treatment for refractory immune thrombocytopenic purpura. | The New England journal of medicine 20010503 |
Endothelial microtubule disruption blocks flow-dependent dilation of arterioles. | American journal of physiology. Heart and circulatory physiology 20010501 |
Effect of P-glycoprotein on flavopiridol sensitivity. | British journal of cancer 20010501 |
Leukocyte rolling in rat mesentery venules: distribution of adhesion bonds and the effects of cytoactive agents. | Annals of biomedical engineering 20010501 |
Sequence of events in the assembly of Mallory body components in mouse liver: clues to the pathogenesis and significance of Mallory body formation. | Journal of hepatology 20010501 |
The water channel aquaporin-8 is mainly intracellular in rat hepatocytes, and its plasma membrane insertion is stimulated by cyclic AMP. | The Journal of biological chemistry 20010413 |
Microtubule disruption by colchicine reversibly enhances calcium signaling in intact rat cardiac myocytes. | Circulation research 20010413 |
P-glycoprotein-mediated colchicine resistance in different cell lines correlates with the effects of colchicine on P-glycoprotein conformation. | Biochemistry 20010410 |
Coordinate changes in drug resistance and drug-induced conformational transitions in altered-function mutants of the multidrug transporter P-glycoprotein. | Biochemistry 20010410 |
Shift in FTIR spectrum patterns in methomyl-exposed rat spleen cells. | The Science of the total environment 20010410 |
Novel sulfonate analogues of combretastatin A-4: potent antimitotic agents. | Bioorganic & medicinal chemistry letters 20010409 |
The effects of tubulin-binding agents on stretch-induced ventricular arrhythmias. | European journal of pharmacology 20010406 |
Functional reassembly of ATP-dependent xenobiotic transport by the N- and C-terminal domains of RLIP76 and identification of ATP binding sequences. | Biochemistry 20010403 |
Behçet's disease with a large intracardiac thrombus: a case report. | Heart (British Cardiac Society) 20010401 |
Sclerosing mesenteritis. | Surgery 20010401 |
Treatment of Behçet's disease--an update. | Seminars in arthritis and rheumatism 20010401 |
Tamoxifen and colchicine-modulated vinblastine followed by 5-fluorouracil in advanced renal cell carcinoma: a phase II study. | Urology 20010401 |
Colchicine for alcoholic and non-alcoholic liver fibrosis or cirrhosis. | Liver 20010401 |
Phosphate wasting in oncogenic osteomalacia: PHEX is normal and the tumor-derived factor has unique properties. | Bone 20010401 |
[Fibroblastic rheumatism: a case report]. | Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20010401 |
Behaviour of microtubules in cells infected with Toxoplasma gondii. | Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al 20010401 |
Cell volume-induced changes in K+ transport across the rat colon. | Acta physiologica Scandinavica 20010401 |
Prolactin levels in Behçet's disease: no correlation with disease manifestations and activity. | Annales de medecine interne 20010401 |
D4 dopamine and metabotropic glutamate receptors in cerebral cortex and striatum in rat brain. | Neurochemical research 20010401 |
Protein kinase C-dependent supply of secretory granules to the plasma membrane. | Biochemical and biophysical research communications 20010330 |
Regulation of ROMK1 channels by protein-tyrosine kinase and -tyrosine phosphatase. | The Journal of biological chemistry 20010309 |
A novel palladium-mediated coupling approach to 2,3-disubstituted benzo(b)thiophenes and its application to the synthesis of tubulin binding agents. | Organic letters 20010308 |
Axon terminals containing CGRP-immunoreactivity form synapses with CRF- and Met-enkephalin-immunopositive neurons in the laterodorsal division of the bed nucleus of the stria terminalis in the rat. | Brain research 20010302 |
Modulation of Ca(2+) signaling by microtubule disruption in rat ventricular myocytes and its dependence on the ruptured patch-clamp configuration. | Circulation research 20010302 |
Calcium ionophore A23187 specifically decreases the secretion of beta-secretase cleaved amyloid precursor protein during apoptosis in primary rat cortical cultures. | Journal of neuroscience research 20010301 |
Microtubule integrity is essential for apical polarization and epithelial morphogenesis in the thyroid. | Cell motility and the cytoskeleton 20010301 |
Physiological concentrations of albumin stimulate chorionic gonadotrophin and placental lactogen release from human term placental explants. | Human reproduction (Oxford, England) 20010301 |
Chromosomal composition of micronuclei in mouse NIH 3T3 cells treated with acrylamide, extract of Tripterygium hypoglaucum (level) hutch, mitomycin C and colchicine, detected by multicolor FISH with centromeric and telomeric DNA probes. | Mutagenesis 20010301 |
Adherence of Giardia lamblia trophozoites to Int-407 human intestinal cells. | Clinical and diagnostic laboratory immunology 20010301 |
Axonal transport of VR1 capsaicin receptor mRNA in primary afferents and its participation in inflammation-induced increase in capsaicin sensitivity. | Journal of neurochemistry 20010301 |
Does the photochemical conversion of colchicine into lumicolchicines involve triplet transients? A solvent dependence study. | Photochemistry and photobiology 20010301 |
Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT. | Immunity 20010301 |
Treatment of chronic gout. Can we determine when urate stores are depleted enough to prevent attacks of gout? | The Journal of rheumatology 20010301 |
Determination of the net exchange rate of tubulin dimer in steady-state microtubules by fluorescence correlation spectroscopy. | Biological chemistry 20010301 |
[A full thickness macular hole as an uncommon complication of Behçet disease]. | Journal francais d'ophtalmologie 20010201 |
Acute fatal colchicine intoxication in a patient on continuous ambulatory peritoneal dialysis (CAPD). Possible role of clarithromycin administration. | Clinical nephrology 20010201 |
Scleroderma. | Dermatology online journal 20010201 |
[Therapeutic criteria in hyperuricemia]. | Revista clinica espanola 20010201 |
Screening of multidrug-resistance sensitive drugs by in situ brain perfusion in P-glycoprotein-deficient mice. | Pharmaceutical research 20010201 |
Antimitotic and cell growth inhibitory properties of combretastatin A-4-like ethers. | Bioorganic & medicinal chemistry letters 20010108 |
Receptor-mediated cell modulator delivery to hepatocyte using nanoparticles coated with carbohydrate-carrying polymers. | Biomaterials 20010101 |
The role of GTP Binding and microtubule-associated proteins in the inhibition of microtubule assembly by carbendazim. | Toxicological sciences : an official journal of the Society of Toxicology 20010101 |
The in vivo gut micronucleus test detects clastogens and aneugens given by gavage. | Mutagenesis 20010101 |
Opposite effects of microtubule-stabilizing and microtubule-destabilizing drugs on biogenesis of mitochondria in mammalian cells. | Journal of cell science 20010101 |
Expression of brain-derived neurotrophic factor in cortical neurons is regulated by striatal target area. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20010101 |
The role of microtubules in guard cell function. | Plant physiology 20010101 |
Colchicine and griseofulvin inhibit VCAM-1 expression on human vascular endothelial cells - evidence for the association of VCAM-1 expression with microtubules. | Journal of dermatological science 20010101 |
Dehydroepiandrosterone sulphate prevents oxygen-glucose deprivation-induced injury in cerebellar granule cell culture. | Neuroscience 20010101 |
Mechanism of colchicine-induced steroidogenesis in rat adrenocortical cells. | Journal of cellular biochemistry 20010101 |
D-24851, a novel synthetic microtubule inhibitor, exerts curative antitumoral activity in vivo, shows efficacy toward multidrug-resistant tumor cells, and lacks neurotoxicity. | Cancer research 20010101 |
Photosensitizing activity of thiocolchicoside: photochemical and in vitro phototoxicity studies. | Die Pharmazie 20010101 |
The stability of cytokeratin 18 in human liver cells during colchicine-induced microtubule disruption. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20010101 |
Effects of combretastatin A4 phosphate on endothelial cell morphology in vitro and relationship to tumour vascular targeting activity in vivo. | Anticancer research 20010101 |
Rapid flow-induced responses in endothelial cells. | Biotechnology progress 20010101 |
[The role of cytoskeleton structures in regulation of Ca2+ responses in macrophages]. | Tsitologiia 20010101 |
Pilot tolerability studies of hydroxychloroquine and colchicine in Alzheimer disease. | Alzheimer disease and associated disorders 20010101 |
Hydrostatic pressure induced changes in the cytoarchitecture of pheochromocytoma (PC-12) cells. | Cell biology international 20010101 |
The effects of hydrostatic pressure-induced changes on the cytoskeleton and on the regulation of gene expression in pheochromocytoma (PC-12) cells. | Cell biology international 20010101 |
Apoptosis in caspase-inhibited neurons. | Molecular medicine (Cambridge, Mass.) 20010101 |
Management of patients with severe oral mucosal disease. | The Alpha omegan 20010101 |
Microtubule disruption modulates the Rho-kinase pathway in vascular smooth muscle. | Journal of muscle research and cell motility 20010101 |
Colchicine for alcoholic and non-alcoholic liver fibrosis and cirrhosis. | The Cochrane database of systematic reviews 20010101 |
Comparative bioavailability and tolerability study of two intramuscular formulations of thiocolchicoside in healthy volunteers. | European journal of drug metabolism and pharmacokinetics 20010101 |
Cytotoxic effects of antiproliferative agents on human retinal glial cells in vitro. | International ophthalmology 20010101 |
[Treatment of AL-amyloidosis and some other types of amyloidosis]. | Vnitrni lekarstvi 20010101 |
Prenatal exposure to high levels of glucocorticoids increases the susceptibility of cerebellar granule cells to oxidative stress-induced cell death. | Proceedings of the National Academy of Sciences of the United States of America 20001219 |
6-Alkylamino- and 2,3-dihydro-3'-methoxy-2-phenyl-4-quinazolinones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization. | Journal of medicinal chemistry 20001116 |
Accumulation of microtubule-based motor protein in a patient with colchicine myopathy. | Neurology 20001114 |
Improvement of renal function in patients with chronic gout after proper control of hyperuricemia and gouty bouts. | Nephron 20001101 |
Slow polymerization of Mycobacterium tuberculosis FtsZ. | Journal of bacteriology 20000701 |
Dissecting cellular processes using small molecules: identification of colchicine-like, taxol-like and other small molecules that perturb mitosis. | Chemistry & biology 20000401 |
Stimulated pulmonary cell hyperplasia underlies resistance to alpha-naphthylthiourea. | Toxicology 20000221 |
Colchicine protects mice from the lethal effect of an agonistic anti-Fas antibody. | The Journal of clinical investigation 20000201 |
[Neuromuscular complications of long-term treatment of inflammatory diseases. 3 cases]. | Annales de medecine interne 19991201 |
Induced differentiation in HT29, a human colon adenocarcinoma cell line. | Journal of cell science 19990801 |
Acute myopathy induced by colchicine in a cyclosporine treated heart transplant recipient: possible role of the multidrug resistance transporter. | Transplantation proceedings 19990801 |
Hypernatraemia and polyuria due to high-dose colchicine in a suicidal patient. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 19990601 |
A monoclonal antibody to alpha-tubulin: purification of functionally active alpha-tubulin isoforms. | Biochemistry 19990427 |
Vagus nerve modulates secretin binding sites in the rat forestomach. | The American journal of physiology 19990401 |
Treatment of linear IgA bullous dermatosis of childhood with colchicine. | Pediatric dermatology 19990101 |
Does the lack of the P-glycoprotein efflux pump in neutrophils explain the efficacy of colchicine in familial Mediterranean fever and other inflammatory diseases? | Medical hypotheses 19981101 |
Colchicine-induced myoneuropathy in childhood. | European journal of pediatrics 19981001 |
A simple method for determining K(A)s of both low and high affinity IgG antibodies. | Journal of immunological methods 19980901 |
Molecular identification of the corticosterone-sensitive extraneuronal catecholamine transporter. | Nature neuroscience 19980901 |
Colchicine in chronic hepatitis B: a pilot study. | Alimentary pharmacology & therapeutics 19980701 |
Colchicine-induced myopathy with myotonia. | Muscle & nerve 19980401 |
Lack of therapeutic effect of colchicine on murine toxoplasmosis. | The Journal of parasitology 19980201 |
Colchicine competitively antagonizes glycine receptors expressed in Xenopus oocytes. | Neuropharmacology 19980101 |
Screening of compounds for antimicrosporidial activity in vitro. | Folia parasitologica 19980101 |
[Pseudotumorous presentation of neuro-Behçet: role of the withdrawal of colchicine?]. | La Revue de medecine interne 19980101 |
An elderly man with acute ataxia. | Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association 19971201 |
Acute onset of colchicine myoneuropathy in cardiac transplant recipients: case studies of three patients. | Clinical neurology and neurosurgery 19971201 |
Colchicine myopathy in renal transplant recipients on cyclosporin. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 19971101 |
Colchicine-induced myopathy in renal failure. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 19971001 |
Muscle weakness due to colchicine in a renal transplant recipient. | The New Zealand medical journal 19970912 |
Regulation of ornithine decarboxylase induction by deguelin, a natural product cancer chemopreventive agent. | Cancer research 19970815 |
Antimitotic intervention with colchicine alters the outcome of o-DCB-induced hepatotoxicity in Fischer 344 rats. | Toxicology 19970627 |
Acute myopathy induced by colchicine in a cyclosporine-treated renal transplant recipient--a case report and review of the literature. | Journal of Korean medical science 19970401 |
Inhibition of sandfly fever Sicilian virus (Phlebovirus) replication in vitro by antiviral compounds. | Research in virology 19970101 |
Effect of Trasina, an ayurvedic herbal formulation, on experimental models of Alzheimer's disease and central cholinergic markers in rats. | Journal of alternative and complementary medicine (New York, N.Y.) 19970101 |
Double knockout of the MRP gene leads to increased drug sensitivity in vitro. | Cancer research 19961201 |
Gap junction endocytosis and lysosomal degradation of connexin43-P2 in WB-F344 rat liver epithelial cells treated with DDT and lindane. | Carcinogenesis 19960901 |
Enhancement of N-nitrosodiethylamine-initiated hepatocarcinogenesis caused by a colchicine-induced cell cycle disturbance in partially hepatectomized rats. | Cancer research 19960801 |
Vasoactive intestinal peptide expression in enteric neurons is upregulated by both colchicine and axotomy. | Regulatory peptides 19960705 |
Myotonia in colchicine myoneuropathy. | Muscle & nerve 19960701 |
Mycobacterium tuberculosis invades and replicates within type II alveolar cells. | Infection and immunity 19960401 |
Colchicine myopathy. | Scandinavian journal of rheumatology 19960101 |
Uptake of human urinary trypsin inhibitor by the kidney epithelial cell line, LLC-PK1. | Pflugers Archiv : European journal of physiology 19960101 |
Colchicine induces apoptosis in cerebellar granule cells. | Experimental cell research 19950501 |
Expression of FGF-2 and FGF receptor type 1 in the adult rat brainstem: effect of colchicine. | The Journal of comparative neurology 19950227 |
A paradoxical regulation of the dopamine D3 receptor expression suggests the involvement of an anterograde factor from dopamine neurons. | Proceedings of the National Academy of Sciences of the United States of America 19950227 |
Chronic colchicine-induced myopathy and neuropathy. | Acta neurologica Belgica 19950101 |
[Colchicine in chronic liver disease of alcoholic etiology. Double-blind, randomized study of its effects on blood levels of plasma proteins and clinical course in patients]. | Revista da Associacao Medica Brasileira (1992) 19950101 |
Comparative pharmacokinetics and bioavailability of two oral formulations of thiocolchicoside, a GABA-mimetic muscle relaxant drug, in normal volunteers. | European journal of drug metabolism and pharmacokinetics 19950101 |
Agonist-induced internalization of the substance P (NK1) receptor expressed in epithelial cells. | The Biochemical journal 19941001 |
Binding of colchicine and thiocolchicoside to human serum proteins and blood cells. | International journal of clinical pharmacology and therapeutics 19940801 |
Colchicine neuromyopathy in a renal transplant patient with normal muscle enzyme levels. | Clinical nephrology 19940701 |
Alterations in Ca2+ transport ATPase and P-glycoprotein expression can mediate resistance to thapsigargin. | The Journal of biological chemistry 19940318 |
Characteristics of P388/VMDRC.04, a simple, sensitive model for studying P-glycoprotein antagonists. | Cancer research 19940201 |
Effect of colchicine on microtubules in Cryptosporidium parvum. | The Journal of eukaryotic microbiology 19940101 |
Single-dose bioavailability of oral and intramuscular thiocolchicoside in healthy volunteers. | Biopharmaceutics & drug disposition 19940101 |
[Myopathy and polyneuropathy caused by colchicine]. | Revista clinica espanola 19930901 |
Vitamin A abuse: development of cirrhosis despite cessation of vitamin A. A six-year clinical and histopathologic follow-up. | Liver 19921201 |
Rapid-onset colchicine myoneuropathy. | Arthritis and rheumatism 19921201 |
Colchicine myoneuropathy and renal dysfunction. | Annals of the rheumatic diseases 19921201 |
Acute neuromyopathy after colchicine treatment. | Annals of the rheumatic diseases 19921101 |
[Toxic myopathy with kidney failure as a colchicine side effect ifn familial Mediterranean fever]. | Deutsche medizinische Wochenschrift (1946) 19920814 |
Colchicine-induced myoneuropathy in a renal transplant patient. | Transplantation 19920601 |
Serum interleukin-2 and tumor necrosis factor-alpha in primary biliary cirrhosis: decrease by colchicine and relationship to HLA-DR4. | The American journal of gastroenterology 19920401 |
Pathobiology of cast nephropathy from human Bence Jones proteins. | The Journal of clinical investigation 19920201 |
Colchicine myopathy in a case of familial Mediterranean fever: immunohistochemical and ultrastructural study of accumulated tubulin-immunoreactive material. | Acta neuropathologica 19920101 |
Biochemical characterization and anatomical distribution of a major form of unamidated precursor of substance P in rat brain. | Brain research 19911220 |
Colchicine-induced myopathy and neuropathy. | Neurology 19910601 |
Renal function predicts colchicine toxicity: guidelines for the prophylactic use of colchicine in gout. | The Journal of rheumatology 19910201 |
Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. | Journal of natural products 19910101 |
Effect of reserpine and colchicine on neuropeptide mRNA levels in the rat hypothalamic paraventricular nucleus. | Brain research. Molecular brain research 19910101 |
Anti-AIDS agents, 3. Inhibitory effects of colchicine derivatives on HIV replication in H9 lymphocyte cells. | Journal of natural products 19910101 |
[Chronic human colchicine myopathy]. | Rinsho shinkeigaku = Clinical neurology 19900901 |
Colchicine neuromyopathy after renal transplantation. | Transplantation 19900601 |
[Neuromuscular toxicity of colchicine. A case]. | Presse medicale (Paris, France : 1983) 19890624 |
Double-masked trial of cyclosporin versus colchicine and long-term open study of cyclosporin in Behçet's disease. | Lancet (London, England) 19890520 |
Electrodiagnosis of human colchicine myoneuropathy. | Muscle & nerve 19890501 |
GM1 ganglioside attenuates the behavioral deficits but not the granule cell damage produced by intradentate colchicine. | Brain research 19890123 |
Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure-activity study. | Molecular pharmacology 19880801 |
Effect of axonal transport blockade on corticotropin-releasing factor immunoreactivity in the median eminence of intact and adrenalectomized rats: relationship between depletion rate and secretory activity. | Brain research 19880301 |
Chronic human colchicine myopathy and neuropathy. | Archives of neurology 19880301 |
Colchicine activates cell cycle-dependent genes in growth-arrested rat 3Y1 cells. | Experimental cell research 19871101 |
Colchicine myopathy and neuropathy. | The New England journal of medicine 19870618 |
Reversible acute cyclosporin nephrotoxicity induced by colchicine administration. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 19870101 |
Chronic human colchicine neuropathy and myopathy. | Archives of neurology 19860501 |
Probenecid induced immune hemolytic anemia. | The Journal of rheumatology 19860201 |
Effects of colchicine on the gallbladder of the mouse. | The Histochemical journal 19860101 |
Chemical and pharmacological studies of 2-(amino-methyl)acrylophenones. | Arzneimittel-Forschung 19860101 |
Ultrastructural changes in the neural tube of 10-day-old mouse embryos exposed to colchicine and hydroxyurea. | Teratology 19850601 |
The colchicine experimental epileptic focus: an intracellular study. | Brain research 19841126 |
Marrow aplasia following colchicine treatment for gouty arthritis. | Clinical and experimental rheumatology 19840101 |
Mechanisms of colchicine neurotoxicity in the dentate gyrus: dissociation of seizures and cell death. | Experimental neurology 19830901 |
Retinal atrophy induced by intravitreous colchicine. | Investigative ophthalmology & visual science 19830301 |
Suppression of spermatogenesis in patients with Behçet's disease treated with cyclophosphamide and colchicine. | Fertility and sterility 19810701 |
Irreversible neuronal damage after intrastriatal injection of colchicine. | Pharmacological research communications 19800701 |
Marrow aplasia induced by colchicine. A case report. | Arthritis and rheumatism 19780101 |
[Medullary aplasia after acute colchicine poisoning. 20 cases]. | La Nouvelle presse medicale 19770507 |
Colchicine inhibits stimulated release of gastric histamine but not activation of histidine decarboxylase. | Experientia 19770315 |
Colchicine toxicity: a multisystem disease. | Archives of internal medicine 19770301 |
Acute myelomonocytic leukaemia and multiple myeloma after sulphinpyrazone and colchicine treatment of gout. | British medical journal 19760710 |
Interaction of oncodazole (R 17934), a new antitumoral drug, with rat brain tubulin. | Biochemical and biophysical research communications 19760322 |
Biliary excretion of colchicine in newborn rats. | Drug metabolism and disposition: the biological fate of chemicals 19750101 |
Colchicine-induced lesions in the rat duodenum. | Pathologia Europaea 19750101 |
Induction of the generalized Shwartzman reaction in pregnant and nonpregnant rats by colchicine. | The American journal of pathology 19721001 |
Porphyria cutanea tarda due to colchicine in patient with gout. | Acta dermato-venereologica 19710101 |
Ultrastructural changes in skeletal muscle induced by colchicine. | Archives of neurology 19710101 |
Trisomy after colchicine therapy. | Lancet (London, England) 19690607 |
Pure red blood cell aplasia associated with chlorpropamide therapy. Patient summary and review of the literature. | Archives of internal medicine 19690401 |
Trisomy after colchicine therapy. | Lancet (London, England) 19690215 |
Probenecid, nephrotic syndrome, and renal failure. | Annals of the rheumatic diseases 19680501 |
[Femoral aneurysm caused by intra-arterial colchicine therapy in gouty arthritis]. | Rivista di anatomia patologica e di oncologia 19680101 |
Nephrotic syndrome caused by probenecid. | JAMA 19670102 |