IMD-0354
| Title | Journal |
|---|---|
| Central IKK2 Inhibition Ameliorates Air Pollution-Mediated Hepatic Glucose and Lipid Metabolism Dysfunction in Mice With Type II Diabetes. | Toxicological sciences : an official journal of the Society of Toxicology 20180701 |
| Identification of potent Yes1 kinase inhibitors using a library screening approach. | Bioorganic & medicinal chemistry letters 20130801 |
| Structure-activity relationships of antitubercular salicylanilides consistent with disruption of the proton gradient via proton shuttling. | Bioorganic & medicinal chemistry 20130101 |
| Salicylanilide inhibitors of Toxoplasma gondii. | Journal of medicinal chemistry 20121011 |
| Activation of nuclear factor-κB pathway is responsible for tumor necrosis factor-α-induced up-regulation of endothelin B2 receptor expression in vascular smooth muscle cells in vitro. | Toxicology letters 20120307 |
| An IκB kinase 2 inhibitor IMD-0354 suppresses the survival of adult T-cell leukemia cells. | Cancer science 20120101 |
| Regulation of cytochrome P450 4F11 by nuclear transcription factor-κB. | Drug metabolism and disposition: the biological fate of chemicals 20120101 |
| A novel IKK inhibitor prevents progression of restenosis after arterial injury in mice. | International heart journal 20120101 |
| Amelioration of endotoxin-induced uveitis treated with an IκB kinase β inhibitor in rats. | Molecular vision 20120101 |
| IκB kinase-beta inhibitor attenuates hepatic fibrosis in mice. | World journal of gastroenterology 20111221 |
| IκB kinase β inhibitor IMD-0354 suppresses airway remodelling in a Dermatophagoides pteronyssinus-sensitized mouse model of chronic asthma. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20110101 |
| Poly(I:C) reduces expression of JAM-A and induces secretion of IL-8 and TNF-α via distinct NF-κB pathways in human nasal epithelial cells. | Toxicology and applied pharmacology 20110101 |
| A novel NF-κB inhibitor improves glucocorticoid sensitivity of canine neoplastic lymphoid cells by up-regulating expression of glucocorticoid receptors. | Research in veterinary science 20101201 |
| Copper activation of NF-kappaB signaling in HepG2 cells. | Journal of molecular biology 20091113 |
| Activation of host antiviral RNA-sensing factors necessary for herpes simplex virus type 1-activated transcription of host cell fucosyltransferase genes FUT3, FUT5, and FUT6 and subsequent expression of sLe(x) in virus-infected cells. | Glycobiology 20090701 |
| Antiallergic and anti-inflammatory effects of a novel I kappaB kinase beta inhibitor, IMD-0354, in a mouse model of allergic inflammation. | International archives of allergy and immunology 20090101 |
| NF-kappaB-mediated HER2 overexpression in radiation-adaptive resistance. | Radiation research 20090101 |
| Effectiveness of IkappaB kinase inhibitors in murine colitis-associated tumorigenesis. | Journal of gastroenterology 20090101 |
| Lipid-soluble smoke particles upregulate vascular smooth muscle ETB receptors via activation of mitogen-activating protein kinases and NF-kappaB pathways. | Toxicological sciences : an official journal of the Society of Toxicology 20081201 |
| Mechanism of signal transduction in tumor necrosis factor-like weak inducer of apoptosis-induced matrix degradation by MMP-3 upregulation in disc tissues. | Spine 20081101 |
| Inhibition of IkappaB kinase beta restrains oncogenic proliferation of pancreatic cancer cells. | Journal of medical and dental sciences 20080301 |
| Simvastatin inhibits TNFalpha-induced invasion of human cardiac myofibroblasts via both MMP-9-dependent and -independent mechanisms. | Journal of molecular and cellular cardiology 20070801 |
| Topical application with a new NF-kappaB inhibitor improves atopic dermatitis in NC/NgaTnd mice. | The Journal of investigative dermatology 20070401 |
| Inhibition of NF-{kappa}B improves left ventricular remodeling and cardiac dysfunction after myocardial infarction. | American journal of physiology. Heart and circulatory physiology 20070101 |
| Thymic stromal lymphopoietin secretion of synovial fibroblasts is positively and negatively regulated by Toll-like receptors/nuclear factor-kappaB pathway and interferon-gamma/dexamethasone. | Modern rheumatology 20070101 |
| A novel IkappaB kinase-beta inhibitor ameliorates bleomycin-induced pulmonary fibrosis in mice. | American journal of respiratory and critical care medicine 20060501 |
| A new IkappaB kinase beta inhibitor prevents human breast cancer progression through negative regulation of cell cycle transition. | Cancer research 20060101 |
| A novel NF-kappaB inhibitor, IMD-0354, suppresses neoplastic proliferation of human mast cells with constitutively activated c-kit receptors. | Blood 20050315 |
| A novel IKKbeta inhibitor stimulates adiponectin levels and ameliorates obesity-linked insulin resistance. | Biochemical and biophysical research communications 20041008 |
| Inhibition of the activation of nuclear factor kappa B to reduce myocardial reperfusion injury and infarct size. | Cardiovascular research 20040701 |
| Inhibition of IkappaB phosphorylation in cardiomyocytes attenuates myocardial ischemia/reperfusion injury. | Cardiovascular research 20040701 |