Home Other Building Blocks 1-Methyl-1-phenylethyl hydroperoxide

1-Methyl-1-phenylethyl hydroperoxide

CAS No.:
80-15-9
Catalog Number:
AG0036JC
Molecular Formula:
C9H12O2
Molecular Weight:
152.1904
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
100g
1 week
United States
$75
- +
Product Description
Catalog Number:
AG0036JC
Chemical Name:
1-Methyl-1-phenylethyl hydroperoxide
CAS Number:
80-15-9
Molecular Formula:
C9H12O2
Molecular Weight:
152.1904
MDL Number:
MFCD00002129
IUPAC Name:
2-hydroperoxypropan-2-ylbenzene
InChI:
InChI=1S/C9H12O2/c1-9(2,11-10)8-6-4-3-5-7-8/h3-7,10H,1-2H3
InChI Key:
YQHLDYVWEZKEOX-UHFFFAOYSA-N
SMILES:
OOC(c1ccccc1)(C)C
EC Number:
201-254-7
UNII:
PG7JD54X4I
RTECS Number:
MX2450000
Properties
Complexity:
115  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
152.084g/mol
Formal Charge:
0
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
152.193g/mol
Monoisotopic Mass:
152.084g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
29.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.7  
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Novel fluorescent probe for detecting hydroperoxides with strong emission in the visible range. Bioorganic & medicinal chemistry letters 20060601
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Testing the vicious cycle theory of mitochondrial ROS production: effects of H2O2 and cumene hydroperoxide treatment on heart mitochondria. Journal of bioenergetics and biomembranes 20060401
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Bioinformatic and enzymatic characterization of the MAPEG superfamily. The FEBS journal 20050401
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Molecular cloning and characterization of alpha-class glutathione S-transferase genes from the hepatopancreas of red sea bream, Pagrus major. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20050101
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Visualization of the antioxidative effects of melatonin at the mitochondrial level during oxidative stress-induced apoptosis of rat brain astrocytes. Journal of pineal research 20040801
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Lipid diffusion in sperm plasma membranes exposed to peroxidative injury from oxygen free radicals. Molecular reproduction and development 20040701
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Effects of released iron, lipid peroxides, and ascorbate in trout hemoglobin-mediated lipid oxidation of washed cod muscle. Journal of agricultural and food chemistry 20040630
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Cyclodextrin-derived diorganyl tellurides as glutathione peroxidase mimics and inhibitors of thioredoxin reductase and cancer cell growth. Journal of medicinal chemistry 20040101
A new method of measuring the antioxidant activity of polyphenols using cumene hydroperoxide. Annals of clinical biochemistry 20040101
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Human glutathione S-transferase A2 polymorphisms: variant expression, distribution in prostate cancer cases/controls and a novel form. Pharmacogenetics 20040101
Oxidative stress in Laeonereis acuta (Polychaeta, Nereididae): environmental and seasonal effects. Marine environmental research 20040101
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Antioxidant properties of Plumbago zeylanica, an Indian medicinal plant and its active ingredient, plumbagin. Redox report : communications in free radical research 20040101
'In vitro' effect of cumene hydroperoxide on hepatic elongation factor-2 and its protection by melatonin. Biochimica et biophysica acta 20031205
Prevention of brain protein and lipid oxidation elicited by a water-soluble oryzanol enzymatic extract derived from rice bran. European journal of nutrition 20031201
Peroxides and macrophages in the toxicity of fine particulate matter in rats. Research report (Health Effects Institute) 20031201
A novel and potent biological antioxidant, Kinobeon A, from cell culture of safflower. Life sciences 20031121
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Measurement of plasma hydroperoxide concentration by FOX-1 assay in conjunction with triphenylphosphine. Clinica chimica acta; international journal of clinical chemistry 20031101
Experimental evidence for the physiological role of bacterial luciferase in the protection of cells against oxidative stress. Current microbiology 20031101
Procyanidins from grape seeds protect endothelial cells from peroxynitrite damage and enhance endothelium-dependent relaxation in human artery: new evidences for cardio-protection. Life sciences 20031017
Catalysis of oxo transfer to prochiral sulfides by oxovanadium(v) compounds that model the active center of haloperoxidases. Chemistry (Weinheim an der Bergstrasse, Germany) 20031006
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Unusual atmospheric pressure chemical ionization conditions for detection of organic peroxides. Journal of mass spectrometry : JMS 20030901
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Separation and identification of DMPO adducts of oxygen-centered radicals formed from organic hydroperoxides by HPLC-ESR, ESI-MS and MS/MS. Journal of the American Society for Mass Spectrometry 20030801
Determination of lipid peroxides in invertebrates tissues using the Fe(III) xylenol orange complex formation. Archives of environmental contamination and toxicology 20030801
Role of yeast glutaredoxins as glutathione S-transferases. The Journal of biological chemistry 20030620
Protective action of CLA against oxidative inactivation of paraoxonase 1, an antioxidant enzyme. Lipids 20030601
Highly enantioselective oxidations of ketene dithioacetals leading to trans bis-sulfoxides. The Journal of organic chemistry 20030516
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Catalytic mechanism of thiol peroxidase from Escherichia coli. Sulfenic acid formation and overoxidation of essential CYS61. The Journal of biological chemistry 20030314
Modulation of biochemical parameters by Hemidesmus indicus in cumene hydroperoxide-induced murine skin: possible role in protection against free radicals-induced cutaneous oxidative stress and tumor promotion. Journal of ethnopharmacology 20030301
Association of mycothiol with protection of Mycobacterium tuberculosis from toxic oxidants and antibiotics. Molecular microbiology 20030301
Determination of organic peroxides by liquid chromatography with on-line post-column ultraviolet irradiation and peroxyoxalate chemiluminescence detection. Journal of chromatography. A 20030214
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Engineering a new C-terminal tail in the H-site of human glutathione transferase P1-1: structural and functional consequences. Journal of molecular biology 20030103
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Assessment of membrane protection by traditional Chinese medicines using a flow cytometric technique: preliminary findings. Redox report : communications in free radical research 20030101
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Cytoprotective and anticancer properties of coenzyme Q versus capsaicin. BioFactors (Oxford, England) 20030101
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Oxidative stress response of rat testis to model prooxidants in vitro and its modulation. Toxicology in vitro : an international journal published in association with BIBRA 20021201
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Evaluation of the roles that alkyl hydroperoxide reductase and Ohr play in organic peroxide-induced gene expression and protection against organic peroxides in Xanthomonas campestris. Biochemical and biophysical research communications 20021129
Complementary DNA cloning, protein expression, and characterization of alpha-class GSTs from Macaca fascicularis liver. Toxicological sciences : an official journal of the Society of Toxicology 20021101
The improved synthesis of OPC-29030, a platelet adhesion inhibitor via diastereoselective oxidation of chiral non-racemic sulfide. Chemical & pharmaceutical bulletin 20021101
Antioxidant balance and free radical generation in vitamin e-deficient mice after dermal exposure to cumene hydroperoxide. Chemical research in toxicology 20021101
Combined effects of cadmium and nickel on testicular xenobiotic metabolizing enzymes in rats. Biological trace element research 20021101
Amperometric enzyme electrode for organic peroxides determination prepared from horseradish peroxidase immobilized in poly(vinylferrocenium) film. Biosensors & bioelectronics 20021001
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GSH-dependent peroxidase activity of the rice (Oryza sativa) glutaredoxin, a thioltransferase. Biochemical and biophysical research communications 20020906
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OhrR, a transcription repressor that senses and responds to changes in organic peroxide levels in Xanthomonas campestris pv. phaseoli. Molecular microbiology 20020901
Determination of superoxide dismutase and glutathione peroxidase activities in blood of healthy pediatric subjects. Clinica chimica acta; international journal of clinical chemistry 20020801
Silica-supported, single-site titanium catalysts for olefin epoxidation. A molecular precursor strategy for control of catalyst structure. Journal of the American Chemical Society 20020717
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Selective peroxidation and externalization of phosphatidylserine in normal human epidermal keratinocytes during oxidative stress induced by cumene hydroperoxide. The Journal of investigative dermatology 20020601
The yeast glutaredoxins are active as glutathione peroxidases. The Journal of biological chemistry 20020510
Stilbazulenyl nitrone (STAZN): a nitronyl-substituted hydrocarbon with the potency of classical phenolic chain-breaking antioxidants. Journal of the American Chemical Society 20020501
Glutathione S-transferase of the malarial parasite Plasmodium falciparum: characterization of a potential drug target. Biological chemistry 20020501
Syntheses and structures of P-anilino-P-chalcogeno- and P-anilino-P-iminodiazasilaphosphetidines and their group 12 and 13 metal compounds. Inorganic chemistry 20020311
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Phenotypic analysis of gene deletant strains for sensitivity to oxidative stress. Yeast (Chichester, England) 20020201
Apoptosis in the initial leaf of etiolated wheat seedlings: influence of the antioxidant ionol (BHT) and peroxides. Biochemistry. Biokhimiia 20020201
Oxidative stress associated DNA damage in testis of mice: induction of abnormal sperms and effects on fertility. Mutation research 20020115
Tryparedoxin peroxidase of Leishmania donovani: molecular cloning, heterologous expression, specificity, and catalytic mechanism. Archives of biochemistry and biophysics 20020115
Asymmetric Weitz-Scheffer epoxidation of isoflavones with hydroperoxides mediated by optically active phase-transfer catalysts. The Journal of organic chemistry 20020111
Oxidant species trigger late preconditioning against myocardial stunning in conscious rabbits. American journal of physiology. Heart and circulatory physiology 20020101
Detection of lipid peroxidation in equine spermatozoa based upon the lipophilic fluorescent dye C1l-BODIPY581/591. Journal of andrology 20020101
Flow cytometric determination of lipid peroxidation using fluoresceinated phosphoethanolamine. Methods in enzymology 20020101
Schistosoma mansoni ferredoxin NADP(H) oxidoreductase and its role in detoxification. Molecular and biochemical parasitology 20020101
Evidence from heterologous expression of glutathione S-transferases A and A1 of the plaice (Pleuronectes platessa) that their endogenous role is in detoxification of lipid peroxidation products. Marine environmental research 20020101
Formation of DNA adducts by microsomal and peroxidase activation of p-cresol: role of quinone methide in DNA adduct formation. Chemico-biological interactions 20011221
Effect of natural phenolic acids on DNA oxidation in vitro. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20011201
Inducers of glycinebetaine synthesis in barley. Plant physiology 20011201
Horseradish peroxidase mediates DNA and deoxyguanosine 3'-monophosphate adduct formation in the presence of ochratoxin A. Archives of toxicology 20011201
Oxidation mechanism of 7-hydroxy-delta 8-tetrahydrocannabinol and 8-hydroxy-delta 9-tetrahydrocannabinol to the corresponding ketones by CYP3A11. Drug metabolism and disposition: the biological fate of chemicals 20011101
Diversity in mechanisms of substrate oxidation by cytochrome P450 2D6. Lack of an allosteric role of NADPH-cytochrome P450 reductase in catalytic regioselectivity. The Journal of biological chemistry 20011026
Multiple glutathione S-transferase isoforms are present on male germ cell plasma membrane. FEBS letters 20011026
Conversion of a peroxiredoxin into a disulfide reductase by a triplet repeat expansion. Science (New York, N.Y.) 20011005
Site-directed mutagenesis of the putative distal helix of peroxygenase cytochrome P450. Archives of biochemistry and biophysics 20011001
Proposed reductive metabolism of artemisinin by glutathione transferases in vitro. Free radical research 20011001
Reaction of melatonin with hemoglobin-derived oxoferryl radicals and inhibition of the hydroperoxide-induced hemoglobin denaturation in red blood cells. Journal of pineal research 20010901
Oxidation of active center cysteine of bovine 1-Cys peroxiredoxin to the cysteine sulfenic acid form by peroxide and peroxynitrite. Free radical biology & medicine 20010801
Catechin metabolism: glutathione conjugate formation catalyzed by tyrosinase, peroxidase, and cytochrome p450. Chemical research in toxicology 20010701
The glutathione peroxidase homologous gene from Chlamydomonas reinhardtii is transcriptionally up-regulated by singlet oxygen. Plant molecular biology 20010701
Studies on calcium oxalate binding proteins: effect of lipid peroxidation. Nephron 20010601
Conjugated triene oxidation products of alpha-farnesene induce symptoms of superficial scald on stored apples. Journal of agricultural and food chemistry 20010601
Purification and characterization of multiple glutathione S-transferase isozymes from Chironomidae larvae. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20010601
The reduction of nitroblue tetrazolium by red blood cells: a measure of Red Cell membrane antioxidant capacity and hemoglobin-membrane binding sites. Free radical research 20010601
Ethidium bromide and SYBR Green I enhance the genotoxicity of UV-irradiation and chemical mutagens in E. coli. Mutation research 20010531
Effects of low iron conditions on the repair of DNA lesions induced by Cumene hydroperoxide in Escherichia coli cells. Mutation research 20010510
Role of THR501 residue in substrate binding and catalytic activity of cytochrome P4501A1. Archives of biochemistry and biophysics 20010501
The antioxidant profile of 2,3-dihydrobenzo[b]furan-5-ol and its 1-thio, 1-seleno, and 1-telluro analogues. Journal of the American Chemical Society 20010418
Decreases in phenytoin hydroxylation activities catalyzed by liver microsomal cytochrome P450 enzymes in phenytoin-treated rats. Drug metabolism and disposition: the biological fate of chemicals 20010401
Antioxidant and radical scavenging properties in vitro of polyphenolic extracts from red wine. European journal of nutrition 20010401
Variants of peroxiredoxins expression in response to hydroperoxide stress. Free radical biology & medicine 20010315
Characterization of metabolic activation of pentachlorophenol to quinones and semiquinones in rodent liver. Chemico-biological interactions 20010314
Thioredoxin peroxidases of the malarial parasite Plasmodium falciparum. European journal of biochemistry 20010301
Mycobacterial FurA is a negative regulator of catalase-peroxidase gene katG. Molecular microbiology 20010301
The influence of GSTM1 null genotype on susceptibility to in vitro oxidative stress. Toxicology 20010126
Role of LYS271 and LYS279 residues in the interaction of cytochrome P4501A1 with NADPH-cytochrome P450 reductase. Archives of biochemistry and biophysics 20010115
Proximal cysteine residue is essential for the enzymatic activities of cytochrome P450cam. European journal of biochemistry 20010101
Phylogenetic analyses and comparative genomics of vitamin B6 (pyridoxine) and pyridoxal phosphate biosynthesis pathways. Journal of molecular microbiology and biotechnology 20010101
Bioconversion of vitamin E acetate in human skin. Current problems in dermatology 20010101
Sensitivity of taurine uptake to oxygen-derived reactive substances in MDR and non-MDR cells. Amino acids 20010101
Modification of natural and artificial polymer colloids by 'topology-controlled' emulsion polymerization. Biomacromolecules 20010101
Red cells from glutathione peroxidase-1-deficient mice have nearly normal defenses against exogenous peroxides. Blood 20000901
A lens glutathione S-transferase, class mu, with thiol-specific antioxidant activity. Experimental eye research 20000901
NADPH- and hydroperoxide-supported 17beta-estradiol hydroxylation catalyzed by a variant form (432L, 453S) of human cytochrome P450 1B1. The Journal of steroid biochemistry and molecular biology 20000901
Gene structure, expression and chromosomal localization of murine theta class glutathione transferase mGSTT1-1. The Biochemical journal 19990101
Sequence, catalytic properties and expression of chicken glutathione-dependent prostaglandin D2 synthase, a novel class Sigma glutathione S-transferase. The Biochemical journal 19980715
Zeta, a novel class of glutathione transferases in a range of species from plants to humans. The Biochemical journal 19971215
Purification and characterization of hepatic glutathione transferases from an insectivorous marsupial, the brown antechinus (Antechinus stuartii). Xenobiotica; the fate of foreign compounds in biological systems 19970601
The R144C change in the CYP2C9*2 allele alters interaction of the cytochrome P450 with NADPH:cytochrome P450 oxidoreductase. Pharmacogenetics 19970601
The Gpx1 gene encodes mitochondrial glutathione peroxidase in the mouse liver. Archives of biochemistry and biophysics 19970401
Increased resistance to oxidative stress in transfected cultured cells overexpressing glutathione S-transferase mGSTA4-4. Toxicology and applied pharmacology 19970301
Preparation and reactions of myoglobin mutants bearing both proximal cysteine ligand and hydrophobic distal cavity: protein models for the active site of P-450. Biochemistry 19961008
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Altered expression of transforming growth factor-beta 1 mRNA and protein in mouse skin carcinogenesis. Molecular carcinogenesis 19940401
Expression, characterization, and tissue distribution of a new cellular selenium-dependent glutathione peroxidase, GSHPx-GI. The Journal of biological chemistry 19930205
Role of phospholipids in reconstituted cytochrome P450 3A form and mechanism of their activation of catalytic activity. Biochemistry 19920707
Distinct oxidoresistance phenotype of human T47D cells transfected by rat glutathione S-transferase Yc expression vectors. The Journal of biological chemistry 19920225
Overexpression of seleno-glutathione peroxidase by gene transfer enhances the resistance of T47D human breast cells to clastogenic oxidants. The Journal of biological chemistry 19911105
The role of NADPH in the regulation of glucose-6-phosphate and 6-phosphogluconate dehydrogenases in rat adipose tissue. Molecular and cellular biochemistry 19910626
Theta, a new class of glutathione transferases purified from rat and man. The Biochemical journal 19910301
Antineoplastic drug sensitivity of human MCF-7 breast cancer cells stably transfected with a human alpha class glutathione S-transferase gene. Cancer research 19910115
A new class of rat glutathione S-transferase Yrs-Yrs inactivating reactive sulfate esters as metabolites of carcinogenic arylmethanols. The Journal of biological chemistry 19900715
Elevation of pi class glutathione S-transferase activity in human breast cancer cells by transfection of the GST pi gene and its effect on sensitivity to toxins. Molecular pharmacology 19890701
Protection of glutathione S-transferase from bilirubin inhibition. Journal of biochemistry 19890601
Human glutathione S-transferases. The Ha multigene family encodes products of different but overlapping substrate specificities. The Journal of biological chemistry 19880915
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