Home Other Building Blocks 5-Aminolevulinic acid methyl ester, HCl

5-Aminolevulinic acid methyl ester, HCl

CAS No.:
79416-27-6
Catalog Number:
AG0036GP
Molecular Formula:
C6H12ClNO3
Molecular Weight:
181.6174
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
98%
In Stock USA
United States
$30
- +
5g
98%
In Stock USA
United States
$88
- +
10g
98%
In Stock USA
United States
$150
- +
25g
98%
In Stock USA
United States
$300
- +
100g
98%
In Stock USA
United States
$900
- +
Product Description
Catalog Number:
AG0036GP
Chemical Name:
5-Aminolevulinic acid methyl ester, HCl
CAS Number:
79416-27-6
Molecular Formula:
C6H12ClNO3
Molecular Weight:
181.6174
MDL Number:
MFCD00012868
IUPAC Name:
methyl 5-amino-4-oxopentanoate;hydrochloride
InChI:
InChI=1S/C6H11NO3.ClH/c1-10-6(9)3-2-5(8)4-7;/h2-4,7H2,1H3;1H
InChI Key:
UJYSYPVQHFNBML-UHFFFAOYSA-N
SMILES:
NCC(=O)CCC(=O)OC.Cl
EC Number:
279-151-1
UNII:
7S73606O1A
Properties
Complexity:
133  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
181.051g/mol
Formal Charge:
0
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
181.616g/mol
Monoisotopic Mass:
181.051g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
69.4A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Comparison of the uptake of 5-aminolevulinic acid and its methyl ester in keratinocytes and skin. Naunyn-Schmiedeberg's archives of pharmacology 20121001
[Fluorescence diagnosis of non-melanoma skin cancer]. Orvosi hetilap 20120826
δ-Aminolevulinic acid and its methyl ester induce the formation of Protoporphyrin IX in cultured sensory neurones. Naunyn-Schmiedeberg's archives of pharmacology 20111201
[Distal onycholysis resolved with photodynamic therapy in an elderly patient on multiple medication]. Enfermedades infecciosas y microbiologia clinica 20111001
Optimization of photodynamic therapy response by survivin gene knockdown in human metastatic breast cancer T47D cells. Journal of photochemistry and photobiology. B, Biology 20110902
Increased cutaneous oxygen availability by topical application of hydrogen peroxide cream enhances the photodynamic reaction to topical 5-aminolevulinic acid-methyl ester. Archives of dermatological research 20110501
Treatment with 5-aminolaevulinic acid methylester is less painful than treatment with 5-aminolaevulinic acid nanoemulsion in topical photodynamic therapy for actinic keratosis. Dermatology (Basel, Switzerland) 20110101
Protoporphyrin IX photobleaching during the light irradiation phase of standard dermatological methyl-aminolevulinate photodynamic therapy. Photodiagnosis and photodynamic therapy 20101201
Microneedle pre-treatment of human skin improves 5-aminolevulininc acid (ALA)- and 5-aminolevulinic acid methyl ester (MAL)-induced PpIX production for topical photodynamic therapy without increase in pain or erythema. Pharmaceutical research 20101001
Efficacy of a methyl ester of 5-aminolevulinic acid in photodynamic therapy for ovarian cancers. Journal of cancer research and clinical oncology 20100801
[Erosive pustulosis on the scalp following dynamic phototherapy]. Annales de dermatologie et de venereologie 20100101
Topical aminolaevulinic acid- and aminolaevulinic acid methyl ester-based photodynamic therapy with red and violet light: influence of wavelength on pain and erythema. The British journal of dermatology 20091101
New aspects in photodynamic therapy of actinic keratoses. Journal of photochemistry and photobiology. B, Biology 20090904
Porphyrin synthesis from aminolevulinic acid esters in endothelial cells and its role in photodynamic therapy. Journal of photochemistry and photobiology. B, Biology 20090904
Pretreatment to enhance protoporphyrin IX accumulation in photodynamic therapy. Dermatology (Basel, Switzerland) 20090101
Images in clinical medicine. Fluorescence diagnosis of subclinical actinic keratoses. The New England journal of medicine 20080508
Identification of tetrapyrrole compounds excreted by Rhodobacter sphaeroides and sources of the methyl hydrogens of bacteriochlorophyll a biosynthesized by R. sphaeroides, based on 13C-NMR spectral analysis of coproporphyrin III tetramethyl ester. Chemical & pharmaceutical bulletin 20070701
Topical photodynamic therapy of actinic keratosis in renal transplant recipients. Transplantation proceedings 20070101
Photodynamic therapy using a methyl ester of 5-aminolevulinic acid in recurrent Paget's disease of the vulva: a pilot study. Gynecologic oncology 20061101
A study comparing endogenous protoporphyrin IX induced by 5-ALA and ALA-methyl ester with exogenous PpIX and PpIX dimethyl ester in photodynamic diagnosis of human nasopharyngeal carcinoma xenografts. International journal of oncology 20061001
The effect of skin permeation enhancers on the formation of porphyrins in mouse skin during topical application of the methyl ester of 5-aminolevulinic acid. Journal of photochemistry and photobiology. B, Biology 20060501
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
The temperature dependence of porphyrin production in Propionibacterium acnes after incubation with 5-aminolevulinic acid (ALA) and its methyl ester (m-ALA). Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20060101
Influence of light exposure on the kinetics of protoporphyrin IX formation in normal skin of hairless mice after application of 5-aminolevulinic acid methyl ester. The Journal of investigative dermatology 20051101
Kinetics of protoporphyrin IX formation in rat oral mucosa and skin after application of 5-aminolevulinic acid and its methylester. Photochemistry and photobiology 20050101
Transdermal delivery from a lipid sponge phase--iontophoretic and passive transport in vitro of 5-aminolevulinic acid and its methyl ester. Journal of controlled release : official journal of the Controlled Release Society 20041124
Iontophoretic delivery of 5-aminolevulinic acid and its methyl ester using a carbopol gel as vehicle. Journal of controlled release : official journal of the Controlled Release Society 20040723
Allergic contact dermatitis to 5-aminolaevulinic acid methylester but not to 5-aminolaevulinic acid after photodynamic therapy. The British journal of dermatology 20040101
A study of 5-aminolevulinic acid and its methyl ester used in in vitro and in vivo systems of human bladder cancer. International journal of oncology 20030201
Comparative in vitro percutaneous penetration of 5-aminolevulinic acid and two of its esters through excised hairless mouse skin. Lasers in surgery and medicine 20030101
The role of light in the treatment of non-melanoma skin cancer using methyl aminolevulinate. The Journal of dermatological treatment 20030101
Clinical efficacy of methyl aminolevulinate (Metvix) photodynamic therapy. The Journal of dermatological treatment 20030101
Methyl aminolevulinate (Metvix) photodynamic therapy - practical pearls. The Journal of dermatological treatment 20030101
Photosensitizing effect of protoporphyrin IX in pigmented melanoma of mice. Biochemical and biophysical research communications 20020927
Weekly topical application of methyl aminolevulinate followed by light exposure delays the appearance of UV-induced skin tumours in mice. Archives of dermatological research 20020701
Protoporphyrin IX fluorescence kinetics in UV-induced tumours and normal skin of hairless mice after topical application of 5-aminolevulinic acid methyl ester. Journal of photochemistry and photobiology. B, Biology 20020501
Protoporphyrin IX distribution following local application of 5-aminolevulinic acid and its esterified derivatives in the tissue layers of the normal rat colon. British journal of cancer 20011101
5-Aminolaevulinic acid methyl ester transport on amino acid carriers in a human colon adenocarcinoma cell line. Photochemistry and photobiology 20010201
Properties