Rotenone
| Title | Journal |
|---|---|
| Food derived respiratory complex I inhibitors modify the effect of Leber hereditary optic neuropathy mutations. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20181001 |
| Dihydronortanshinone, a natural product, alleviates LPS-induced inflammatory response through NF-κB, mitochondrial ROS, and MAPK pathways. | Toxicology and applied pharmacology 20180915 |
| Neuroprotective effect of angiotensin-(1-7) against rotenone-induced oxidative damage in CATH.a neurons. | Toxicology in vitro : an international journal published in association with BIBRA 20180801 |
| Downregulation of metabotropic glutamate receptor 5 inhibits hepatoma development in a neurotoxin rotenone-induced Parkinson's disease model. | Toxicology letters 20180515 |
| Toxicity, recovery, and resilience in a 3D dopaminergic neuronal in vitro model exposed to rotenone. | Archives of toxicology 20180101 |
| Editor's Highlight: Nlrp3 Is Required for Inflammatory Changes and Nigral Cell Loss Resulting From Chronic Intragastric Rotenone Exposure in Mice. | Toxicological sciences : an official journal of the Society of Toxicology 20170901 |
| Deficiencies in mitochondrial dynamics sensitize Caenorhabditis elegans to arsenite and other mitochondrial toxicants by reducing mitochondrial adaptability. | Toxicology 20170715 |
| Thymoquinone exerts neuroprotective effect in animal model of Parkinson's disease. | Toxicology letters 20170705 |
| Effects of Inorganic Arsenic, Methylated Arsenicals, and Arsenobetaine on Atherosclerosis in the Mouse Model and the Role of As3mt-Mediated Methylation. | Environmental health perspectives 20170701 |
| The effects of rotenone-induced toxicity via the NF-κB-iNOS pathway in rat liver. | Toxicology mechanisms and methods 20170501 |
| Ultrafine carbon particles promote rotenone-induced dopamine neuronal loss through activating microglial NADPH oxidase. | Toxicology and applied pharmacology 20170501 |
| Sab mediates mitochondrial dysfunction involved in imatinib mesylate-induced cardiotoxicity. | Toxicology 20170501 |
| Protective role of apigenin on rotenone induced rat model of Parkinson's disease: Suppression of neuroinflammation and oxidative stress mediated apoptosis. | Chemico-biological interactions 20170501 |
| DJ-1 regulating PI3K-Nrf2 signaling plays a significant role in bibenzyl compound 20C-mediated neuroprotection against rotenone-induced oxidative insult. | Toxicology letters 20170405 |
| Rifampicin pre-treatment inhibits the toxicity of rotenone-induced PC12 cells by enhancing sumoylation modification of α-synuclein. | Biochemical and biophysical research communications 20170325 |
| RNA-Seq Expression Analysis of Enteric Neuron Cells with Rotenone Treatment and Prediction of Regulated Pathways. | Neurochemical research 20170201 |
| Harmonization of Mangiferin on methylmercury engendered mitochondrial dysfunction. | Environmental toxicology 20170201 |
| Neonatal rotenone lesions cause onset of hyperactivity during juvenile and adulthood in the rat. | Toxicology letters 20170115 |
| Antitumor effects of deguelin on H460 human lung cancer cells in vitro and in vivo: Roles of apoptotic cell death and H460 tumor xenografts model. | Environmental toxicology 20170101 |
| Interaction between subclinical doses of the Parkinson's disease associated gene, α-synuclein, and the pesticide, rotenone, precipitates motor dysfunction and nigrostriatal neurodegeneration in rats. | Behavioural brain research 20170101 |
| Parkinson's disease-like motor and non-motor symptoms in rotenone-treated zebrafish. | Neurotoxicology 20170101 |
| BAG5 Interacts with DJ-1 and Inhibits the Neuroprotective Effects of DJ-1 to Combat Mitochondrial Oxidative Damage. | Oxidative medicine and cellular longevity 20170101 |
| Safranal prevents rotenone-induced oxidative stress and apoptosis in an in vitro model of Parkinson's disease through regulating Keap1/Nrf2 signaling pathway. | Cellular and molecular biology (Noisy-le-Grand, France) 20161230 |
| Curcumin Monoglucoside Shows Improved Bioavailability and Mitigates Rotenone Induced Neurotoxicity in Cell and Drosophila Models of Parkinson's Disease. | Neurochemical research 20161101 |
| From the Cover: Alterations in Optineurin Expression and Localization in Pre-clinical Parkinson's Disease Models. | Toxicological sciences : an official journal of the Society of Toxicology 20161001 |
| Neuroprotective effects of pyrroloquinoline quinone against rotenone injury in primary cultured midbrain neurons and in a rat model of Parkinson's disease. | Neuropharmacology 20160901 |
| Upregulation of the cannabinoid CB2 receptor in environmental and viral inflammation-driven rat models of Parkinson's disease. | Experimental neurology 20160901 |
| SIRT3 Acts as a Neuroprotective Agent in Rotenone-Induced Parkinson Cell Model. | Neurochemical research 20160701 |
| Ameliorative Effect of Quercetin on Neurochemical and Behavioral Deficits in Rotenone Rat Model of Parkinson's Disease: Modulating Autophagy (Quercetin on Experimental Parkinson's Disease). | Journal of biochemical and molecular toxicology 20160701 |
| Previously Unclassified Mutation of mtDNA m.3472T>C: Evidence of Pathogenicity in Leber's Hereditary Optic Neuropathy. | Biochemistry. Biokhimiia 20160701 |
| 20C, a bibenzyl compound isolated from Gastrodia elata, protects PC12 cells against rotenone-induced apoptosis via activation of the Nrf2/ARE/HO-1 signaling pathway. | Acta pharmacologica Sinica 20160601 |
| Modulatory effects of resveratrol on endoplasmic reticulum stress-associated apoptosis and oxido-inflammatory markers in a rat model of rotenone-induced Parkinson's disease. | Chemico-biological interactions 20160505 |
| Downregulation of miR-384-5p attenuates rotenone-induced neurotoxicity in dopaminergic SH-SY5Y cells through inhibiting endoplasmic reticulum stress. | American journal of physiology. Cell physiology 20160501 |
| Rotenone down-regulates HSPA8/hsc70 chaperone protein in vitro: A new possible toxic mechanism contributing to Parkinson's disease. | Neurotoxicology 20160501 |
| Tracking micro-optical resonances for identifying and sensing novel procaspase-3 protein marker released from cell cultures in response to toxins. | Nanotechnology 20160422 |
| Ursodeoxycholic Acid Ameliorates Apoptotic Cascade in the Rotenone Model of Parkinson's Disease: Modulation of Mitochondrial Perturbations. | Molecular neurobiology 20160301 |
| Expression changes of genes associated with apoptosis and survival processes in Parkinson's disease. | Neuroscience letters 20160226 |
| Endoplasmic Reticulum Stress Plays a Key Role in Rotenone-Induced Apoptotic Death of Neurons. | Molecular neurobiology 20160101 |
| Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20160101 |
| Evidence of neuroprotective effects of saffron and crocin in a Drosophila model of parkinsonism. | Neurotoxicology 20160101 |
| Resveratrol Regulates Mitochondrial Biogenesis and Fission/Fusion to Attenuate Rotenone-Induced Neurotoxicity. | Oxidative medicine and cellular longevity 20160101 |
| Impairing autophagy in retinal pigment epithelium leads to inflammasome activation and enhanced macrophage-mediated angiogenesis. | Scientific reports 20160101 |
| Identification of chemicals that mimic transcriptional changes associated with autism, brain aging and neurodegeneration. | Nature communications 20160101 |
| Enhancing Beta-Catenin Activity via GSK3beta Inhibition Protects PC12 Cells against Rotenone Toxicity through Nurr1 Induction. | PloS one 20160101 |
| Suppressed translation and ULK1 degradation as potential mechanisms of autophagy limitation under prolonged starvation. | Autophagy 20160101 |
| L10P mutation in DJ-1 gene induced oxidative stress and mitochondrial disfunction. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20151201 |
| Pyrroloquinoline quinone-conferred neuroprotection in rotenone models of Parkinson's disease. | Toxicology letters 20151104 |
| Rifampicin attenuates rotenone-induced inflammation via suppressing NLRP3 inflammasome activation in microglia. | Brain research 20151005 |
| An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death. | The Journal of biological chemistry 20150821 |
| Synthesis and Evaluation of a Novel Deguelin Derivative, L80, which Disrupts ATP Binding to the C-terminal Domain of Heat Shock Protein 90. | Molecular pharmacology 20150801 |
| Rotenone affects p53 transcriptional activity and apoptosis via targeting SIRT1 and H3K9 acetylation in SH-SY5Y cells. | Journal of neurochemistry 20150801 |
| Sestrin2 Protects Dopaminergic Cells against Rotenone Toxicity through AMPK-Dependent Autophagy Activation. | Molecular and cellular biology 20150801 |
| shRNA targeting α-synuclein prevents neurodegeneration in a Parkinson's disease model. | The Journal of clinical investigation 20150701 |
| Utilization of human nuclear receptors as an early counter screen for off-target activity: a case study with a compendium of 615 known drugs. | Toxicological sciences : an official journal of the Society of Toxicology 20150601 |
| Pyrroloquinoline quinone (PQQ) producing Escherichia coli Nissle 1917 (EcN) alleviates age associated oxidative stress and hyperlipidemia, and improves mitochondrial function in ageing rats. | Experimental gerontology 20150601 |
| Rotenone Stereospecifically Increases (S)-2-Hydroxyglutarate in SH-SY5Y Neuronal Cells. | Chemical research in toxicology 20150518 |
| GAPDH-knockdown reduce rotenone-induced H9C2 cells death via autophagy and anti-oxidative stress pathway. | Toxicology letters 20150505 |
| Methylmercury impairs canonical dopamine metabolism in rat undifferentiated pheochromocytoma (PC12) cells by indirect inhibition of aldehyde dehydrogenase. | Toxicological sciences : an official journal of the Society of Toxicology 20150401 |
| Cholesteryl ester-transfer protein inhibitors stimulate aldosterone biosynthesis in adipocytes through Nox-dependent processes. | The Journal of pharmacology and experimental therapeutics 20150401 |
| The molecular mechanism of rotenone-induced α-synuclein aggregation: emphasizing the role of the calcium/GSK3β pathway. | Toxicology letters 20150304 |
| JNK inhibition of VMAT2 contributes to rotenone-induced oxidative stress and dopamine neuron death. | Toxicology 20150203 |
| Deguelin, a selective silencer of the NPM1 mutant, potentiates apoptosis and induces differentiation in AML cells carrying the NPM1 mutation. | Annals of hematology 20150201 |
| Daily rhythms of serotonin metabolism and the expression of clock genes in suprachiasmatic nucleus of rotenone-induced Parkinson's disease male Wistar rat model and effect of melatonin administration. | Biogerontology 20150201 |
| Saxagliptin: a novel antiparkinsonian approach. | Neuropharmacology 20150201 |
| Protective glove use and hygiene habits modify the associations of specific pesticides with Parkinson's disease. | Environment international 20150201 |
| Biomolecular characterization of exosomes released from cancer stem cells: Possible implications for biomarker and treatment of cancer. | Oncotarget 20150201 |
| Neuroprotective effects of aldehyde dehydrogenase 2 activation in rotenone-induced cellular and animal models of parkinsonism. | Experimental neurology 20150101 |
| Rotenone induction of hydrogen peroxide inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E pathways, leading to neuronal apoptosis. | Toxicological sciences : an official journal of the Society of Toxicology 20150101 |
| Angiotensin AT2 receptor stimulation inhibits activation of NADPH oxidase and ameliorates oxidative stress in rotenone model of Parkinson's disease in CATH.a cells. | Neurotoxicology and teratology 20150101 |
| Neuroprotective effects of bee venom acupuncture therapy against rotenone-induced oxidative stress and apoptosis. | Neurochemistry international 20150101 |
| Inhibition of Mitochondrial Complex-1 Prevents the Downregulation of NKCC2 and ENaCα in Obstructive Kidney Disease. | Scientific reports 20150101 |
| Deguelin inhibits the migration and invasion of lung cancer A549 and H460 cells via regulating actin cytoskeleton rearrangement. | International journal of clinical and experimental pathology 20150101 |
| Ellagic acid mitigates SNO-PDI induced aggregation of Parkinsonian biomarkers. | ACS chemical neuroscience 20141217 |
| Cell therapy using retinal progenitor cells shows therapeutic effect in a chemically-induced rotenone mouse model of Leber hereditary optic neuropathy. | European journal of human genetics : EJHG 20141101 |
| Deguelin inhibits the migration and invasion of U-2 OS human osteosarcoma cells via the inhibition of matrix metalloproteinase-2/-9 in vitro. | Molecules (Basel, Switzerland) 20141015 |
| Overexpression of human E46K mutant α-synuclein impairs macroautophagy via inactivation of JNK1-Bcl-2 pathway. | Molecular neurobiology 20141001 |
| Mitochondrial reactive oxygen species are scavenged by Cockayne syndrome B protein in human fibroblasts without nuclear DNA damage. | Proceedings of the National Academy of Sciences of the United States of America 20140916 |
| Downregulation of Pink1 influences mitochondrial fusion-fission machinery and sensitizes to neurotoxins in dopaminergic cells. | Neurotoxicology 20140901 |
| Downregulation of cystathionine β-synthase/hydrogen sulfide contributes to rotenone-induced microglia polarization toward M1 type. | Biochemical and biophysical research communications 20140822 |
| [Protective effect of baicalin against rotenone induced injury on PC12 cells]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20140801 |
| RTP801 regulates maneb- and mancozeb-induced cytotoxicity via NF-κB. | Journal of biochemical and molecular toxicology 20140701 |
| Rotenone, a mitochondrial respiratory complex I inhibitor, ameliorates lipopolysaccharide/D-galactosamine-induced fulminant hepatitis in mice. | International immunopharmacology 20140701 |
| Involvement of ERK1/2 pathway in neuroprotective effects of pyrroloquinoline quinine against rotenone-induced SH-SY5Y cell injury. | Neuroscience 20140613 |
| Dopamine down-regulation of protein L-isoaspartyl methyltransferase is dependent on reactive oxygen species in SH-SY5Y cells. | Neuroscience 20140516 |
| Natural pesticide dihydrorotenone arrests human plasma cancer cells at the G0/G1 phase of the cell cycle. | Journal of biochemical and molecular toxicology 20140501 |
| Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP(+). | Cell death & disease 20140501 |
| PPARγ activation rescues mitochondrial function from inhibition of complex I and loss of PINK1. | Experimental neurology 20140301 |
| TNF-α mediates mitochondrial uncoupling and enhances ROS-dependent cell migration via NF-κB activation in liver cells. | FEBS letters 20140103 |
| Dietary fat intake, pesticide use, and Parkinson's disease. | Parkinsonism & related disorders 20140101 |
| Resveratrol partially prevents rotenone-induced neurotoxicity in dopaminergic SH-SY5Y cells through induction of heme oxygenase-1 dependent autophagy. | International journal of molecular sciences 20140101 |
| BAG5 protects against mitochondrial oxidative damage through regulating PINK1 degradation. | PloS one 20140101 |
| Rifampicin protects PC12 cells from rotenone-induced cytotoxicity by activating GRP78 via PERK-eIF2α-ATF4 pathway. | PloS one 20140101 |
| Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1α transcription. | Cell 20131205 |
| Release of targeted p53 from the mitochondrion as an early signal during mitochondrial dysfunction. | Cellular signalling 20131201 |
| Rotenone-induced oxidative stress and apoptosis in human liver HepG2 cells. | Molecular and cellular biochemistry 20131201 |
| Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model. | Toxicological sciences : an official journal of the Society of Toxicology 20131201 |
| Impairment of Atg5-dependent autophagic flux promotes paraquat- and MPP⁺-induced apoptosis but not rotenone or 6-hydroxydopamine toxicity. | Toxicological sciences : an official journal of the Society of Toxicology 20131101 |
| 14-3-3 Proteins in the regulation of rotenone-induced neurotoxicity might be via its isoform 14-3-3epsilon's involvement in autophagy. | Cellular and molecular neurobiology 20131101 |
| Rotenone induces neuronal death by microglial phagocytosis of neurons. | The FEBS journal 20131001 |
| Complex I inhibition in the visual pathway induces disorganization of the node of Ranvier. | Neurobiology of disease 20131001 |
| Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells. | Nature cell biology 20131001 |
| Deguelin suppresses pancreatic tumor growth and metastasis by inhibiting epithelial-to-mesenchymal transition in an orthotopic model. | Oncogene 20130822 |
| The NLRP3 inflammasome affects DNA damage responses after oxidative and genotoxic stress in dendritic cells. | European journal of immunology 20130801 |
| Rotenone could activate microglia through NFκB associated pathway. | Neurochemical research 20130801 |
| Gastrodin ameliorates Parkinson's disease by downregulating connexin 43. | Molecular medicine reports 20130801 |
| Valeriana officinalis attenuates the rotenone-induced toxicity in Drosophila melanogaster. | Neurotoxicology 20130701 |
| Reactive oxygen species regulate context-dependent inhibition of NFAT5 target genes. | Experimental & molecular medicine 20130701 |
| Chronic oxidative stress modulates TRPC3 and TRPM2 channel expression and function in rat primary cortical neurons: relevance to the pathophysiology of bipolar disorder. | Brain research 20130623 |
| Neonatal exposure to lipopolysaccharide enhances accumulation of α-synuclein aggregation and dopamine transporter protein expression in the substantia nigra in responses to rotenone challenge in later life. | Toxicology 20130607 |
| Polyphenols protect the epithelial barrier function of Caco-2 cells exposed to indomethacin through the modulation of occludin and zonula occludens-1 expression. | Journal of agricultural and food chemistry 20130605 |
| Relative expression of cholesterol transport-related proteins and inflammation markers through the induction of 7-ketosterol-mediated stress in Caco-2 cells. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20130601 |
| MCJ/DnaJC15, an endogenous mitochondrial repressor of the respiratory chain that controls metabolic alterations. | Molecular and cellular biology 20130601 |
| Specific pesticide-dependent increases in α-synuclein levels in human neuroblastoma (SH-SY5Y) and melanoma (SK-MEL-2) cell lines. | Toxicological sciences : an official journal of the Society of Toxicology 20130601 |
| MicroRNA-195 targets ADP-ribosylation factor-like protein 2 to induce apoptosis in human embryonic stem cell-derived neural progenitor cells. | Cell death & disease 20130601 |
| Quercetin up-regulates mitochondrial complex-I activity to protect against programmed cell death in rotenone model of Parkinson's disease in rats. | Neuroscience 20130416 |
| The behavioural and neuropathological impact of intranigral AAV-α-synuclein is exacerbated by systemic infusion of the Parkinson's disease-associated pesticide, rotenone, in rats. | Behavioural brain research 20130415 |
| Gene expression profiling of rotenone-mediated cortical neuronal death: evidence for inhibition of ubiquitin-proteasome system and autophagy-lysosomal pathway, and dysfunction of mitochondrial and calcium signaling. | Neurochemistry international 20130401 |
| Rotenone-dependent changes of anterograde motor protein expression and mitochondrial mobility in brain areas related to neurodegenerative diseases. | Cellular and molecular neurobiology 20130401 |
| Reactive oxygen species-responsive miR-210 regulates proliferation and migration of adipose-derived stem cells via PTPN2. | Cell death & disease 20130401 |
| A DNA methyltransferase inhibitor, 5-aza-2'-deoxycytidine, exacerbates neurotoxicity and upregulates Parkinson's disease-related genes in dopaminergic neurons. | CNS neuroscience & therapeutics 20130301 |
| Expression of human E46K-mutated α-synuclein in BAC-transgenic rats replicates early-stage Parkinson's disease features and enhances vulnerability to mitochondrial impairment. | Experimental neurology 20130201 |
| Transient exposure to echinacoside is sufficient to activate Trk signaling and protect neuronal cells from rotenone. | Journal of neurochemistry 20130201 |
| The mechanism of alternative splicing of the X-linked NDUFB11 gene of the respiratory chain complex I, impact of rotenone treatment in neuroblastoma cells. | Biochimica et biophysica acta 20130201 |
| Rotenone-induced neurotoxicity in rat brain areas: a study on neuronal and neuronal supportive cells. | Neuroscience 20130129 |
| Therapeutic effects of human mesenchymal and hematopoietic stem cells on rotenone-treated parkinsonian mice. | Journal of neuroscience research 20130101 |
| Use of transgenic GFP reporter strains of the nematode Caenorhabditis elegans to investigate the patterns of stress responses induced by pesticides and by organic extracts from agricultural soils. | Ecotoxicology (London, England) 20130101 |
| Resveratrol confers protection against rotenone-induced neurotoxicity by modulating myeloperoxidase levels in glial cells. | PloS one 20130101 |
| Rotenone upregulates alpha-synuclein and myocyte enhancer factor 2D independently from lysosomal degradation inhibition. | BioMed research international 20130101 |
| Characterization of cellular protective effects of ATP13A2/PARK9 expression and alterations resulting from pathogenic mutants. | Journal of neuroscience research 20121201 |
| Mitochondrial ROS-K+ channel signaling pathway regulated secretion of human pulmonary artery endothelial cells. | Free radical research 20121201 |
| RIP1-mediated mitochondrial dysfunction and ROS production contributed to tumor necrosis factor alpha-induced L929 cell necroptosis and autophagy. | International immunopharmacology 20121201 |
| Environmental toxicants as extrinsic epigenetic factors for parkinsonism: studies employing transgenic C. elegans model. | CNS & neurological disorders drug targets 20121201 |
| ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons. | Human molecular genetics 20121115 |
| Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine. | Bioorganic & medicinal chemistry 20121115 |
| Evidence for synergism between cell death mechanisms in a cellular model of neurodegeneration in Parkinson's disease. | Neurotoxicity research 20121101 |
| Deguelin, an Akt inhibitor, down-regulates NF-κB signaling and induces apoptosis in colon cancer cells and inhibits tumor growth in mice. | Digestive diseases and sciences 20121101 |
| High-energy compounds promote physiological processing of Alzheimer's amyloid-β precursor protein and boost cell survival in culture. | Journal of neurochemistry 20121101 |
| Cadmium-induced apoptosis in the BJAB human B cell line: involvement of PKC/ERK1/2/JNK signaling pathways in HO-1 expression. | Toxicology 20121028 |
| Delivering instilled hydrophobic drug to the bladder by a cationic nanoparticle and thermo-sensitive hydrogel composite system. | Nanoscale 20121021 |
| DJ-1 protects dopaminergic neurons against rotenone-induced apoptosis by enhancing ERK-dependent mitophagy. | Journal of molecular biology 20121019 |
| The neurogenic basic helix-loop-helix transcription factor NeuroD6 enhances mitochondrial biogenesis and bioenergetics to confer tolerance of neuronal PC12-NeuroD6 cells to the mitochondrial stressor rotenone. | Experimental cell research 20121015 |
| Mitochondrial bioenergetics and drug-induced toxicity in a panel of mouse embryonic fibroblasts with mitochondrial DNA single nucleotide polymorphisms. | Toxicology and applied pharmacology 20121015 |
| Molecular responses differ between sensitive silver carp and tolerant bighead carp and bigmouth buffalo exposed to rotenone. | Fish physiology and biochemistry 20121001 |
| Oxidized phospholipids as biomarkers of tissue and cell damage with a focus on cardiolipin. | Biochimica et biophysica acta 20121001 |
| Detection of ischemic neuronal damage with [¹⁸F]BMS-747158-02, a mitochondrial complex-1 positron emission tomography ligand: small animal PET study in rat brain. | Synapse (New York, N.Y.) 20121001 |
| Astrocyte activation: a key step in rotenone induced cytotoxicity and DNA damage. | Neurochemical research 20121001 |
| AIF depletion provides neuroprotection through a preconditioning effect. | Apoptosis : an international journal on programmed cell death 20121001 |
| Rotenone induces KATP channel opening in PC12 cells in association with the expression of tyrosine hydroxylase. | Oncology reports 20121001 |
| Rotenone-induced parkinsonism elicits behavioral impairments and differential expression of parkin, heat shock proteins and caspases in the rat. | Neuroscience 20120918 |
| Effect of a high dose of simvastatin on muscle mitochondrial metabolism and calcium signaling in healthy volunteers. | Toxicology and applied pharmacology 20120915 |
| A new antifungal and cytotoxic C-methylated flavone glycoside from Picea neoveitchii. | Bioorganic & medicinal chemistry letters 20120915 |
| Glycogen synthase kinase-3β activation mediates rotenone-induced cytotoxicity with the involvement of microtubule destabilization. | Biochemical and biophysical research communications 20120914 |
| Rotenone-induced apoptosis and role of calcium: a study on Neuro-2a cells. | Archives of toxicology 20120901 |
| Administration of rotenone enhanced voluntary alcohol drinking behavior in C57BL/6J mice. | Legal medicine (Tokyo, Japan) 20120901 |
| Inhibition of complex I regulates the mitochondrial permeability transition through a phosphate-sensitive inhibitory site masked by cyclophilin D. | Biochimica et biophysica acta 20120901 |
| Alterations in bioenergetic function induced by Parkinson's disease mimetic compounds: lack of correlation with superoxide generation. | Journal of neurochemistry 20120901 |
| Role of metabotropic glutamate receptors in the mechanisms of experimental parkinsonism development. | Bulletin of experimental biology and medicine 20120901 |
| Novel role of PKR in inflammasome activation and HMGB1 release. | Nature 20120830 |
| Dl-3-n-butylphthalide, a natural antioxidant, protects dopamine neurons in rotenone models for Parkinson's disease. | Neurobiology of aging 20120801 |
| Mitochondrial complex I inhibitor rotenone-induced toxicity and its potential mechanisms in Parkinson's disease models. | Critical reviews in toxicology 20120801 |
| Acute exposure to the mitochondrial complex I toxin rotenone impairs synaptic long-term potentiation in rat hippocampal slices. | CNS neuroscience & therapeutics 20120801 |
| Nickel-induced epithelial-mesenchymal transition by reactive oxygen species generation and E-cadherin promoter hypermethylation. | The Journal of biological chemistry 20120720 |
| Chrysotoxine, a novel bibenzyl compound selectively antagonizes MPP⁺, but not rotenone, neurotoxicity in dopaminergic SH-SY5Y cells. | Neuroscience letters 20120711 |
| Methylene blue protects primary rat retinal ganglion cells from cellular senescence. | Investigative ophthalmology & visual science 20120710 |
| Selective protection of nigral dopaminergic neurons by echinacoside in a rat model of Parkinson disease induced by rotenone. | Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20120701 |
| The joint action of destruxins and botanical insecticides (rotenone, azadirachtin and paeonolum) against the cotton aphid, Aphis gossypii Glover. | Molecules (Basel, Switzerland) 20120618 |
| Mitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation. | Antioxidants & redox signaling 20120615 |
| The dopaminergic stabilizer, (-)-OSU6162, rescues striatal neurons with normal and expanded polyglutamine chains in huntingtin protein from exposure to free radicals and mitochondrial toxins. | Brain research 20120612 |
| Neurotoxin-based models of Parkinson's disease. | Neuroscience 20120601 |
| Peripheral inflammation increases the deleterious effect of CNS inflammation on the nigrostriatal dopaminergic system. | Neurotoxicology 20120601 |
| Chemical constituents of the aerial part of Derris elliptica. | Fitoterapia 20120601 |
| Effect of pesticides on the aggregation of mutant huntingtin protein. | Molecular neurobiology 20120601 |
| Propensity of Selaginella delicatula aqueous extract to offset rotenone-induced oxidative dysfunctions and neurotoxicity in Drosophila melanogaster: Implications for Parkinson's disease. | Neurotoxicology 20120601 |
| NMDA alters rotenone toxicity in rat substantia nigra zona compacta and ventral tegmental area dopamine neurons. | Neurotoxicology 20120601 |
| In vitro inhibition of pigmentation and fiber development in colored cotton. | Journal of Zhejiang University. Science. B 20120601 |
| Screening of anti-cancer agent using zebrafish: comparison with the MTT assay. | Biochemical and biophysical research communications 20120525 |
| Fish oil prophylaxis attenuates rotenone-induced oxidative impairments and mitochondrial dysfunctions in rat brain. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120501 |
| Mitochondrial respiration in ME-CAM, PEPCK-CAM, and C₃ succulents: comparative operation of the cytochrome, alternative, and rotenone-resistant pathways. | Journal of experimental botany 20120501 |
| Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs. | Toxicological sciences : an official journal of the Society of Toxicology 20120501 |
| Rotenone-induced death of RGC-5 cells is caspase independent, involves the JNK and p38 pathways and is attenuated by specific green tea flavonoids. | Neurochemical research 20120501 |
| Rotenone formulation fate in Lake Davis following the 2007 treatment. | Environmental toxicology and chemistry 20120501 |
| Glutamate-induced free radical formation in rat brain synaptosomes is not dependent on intrasynaptosomal mitochondria membrane potential. | Neuroscience letters 20120404 |
| Neuroprotection of kaempferol by autophagy in models of rotenone-mediated acute toxicity: possible implications for Parkinson's disease. | Neurobiology of aging 20120401 |
| Behavioral, neurochemical and histological alterations promoted by bilateral intranigral rotenone administration: a new approach for an old neurotoxin. | Neurotoxicity research 20120401 |
| Bacopa monnieri extract offsets rotenone-induced cytotoxicity in dopaminergic cells and oxidative impairments in mice brain. | Cellular and molecular neurobiology 20120401 |
| Differing effects of toxicants (methylmercury, inorganic mercury, lead, amyloid β, and rotenone) on cultured rat cerebrocortical neurons: differential expression of rho proteins associated with neurotoxicity. | Toxicological sciences : an official journal of the Society of Toxicology 20120401 |
| Induction of DNA damage by deguelin is mediated through reducing DNA repair genes in human non-small cell lung cancer NCI-H460 cells. | Oncology reports 20120401 |
| Acute feedback control of astrocytic glycolysis by lactate. | Glia 20120401 |
| Mitochondrial electron transport and glycolysis are coupled in articular cartilage. | Osteoarthritis and cartilage 20120401 |
| Brown adipose tissue mitochondria oxidizing fatty acids generate high levels of reactive oxygen species irrespective of the uncoupling protein-1 activity state. | Biochimica et biophysica acta 20120301 |
| Effects of mitochondrial poisons on the neuropathic pain produced by the chemotherapeutic agents, paclitaxel and oxaliplatin. | Pain 20120301 |
| Astrocyte mediated protection of fetal cerebral cortical neurons from rotenone and paraquat. | Environmental toxicology and pharmacology 20120301 |
| Decrease in nicotinamide adenine dinucleotide dehydrogenase is related to skin pigmentation. | Journal of cosmetic dermatology 20120301 |
| Effect of oxidative stress on TRPM2 and TRPC3 channels in B lymphoblast cells in bipolar disorder. | Bipolar disorders 20120301 |
| [Cysteinyl leukotriene receptor 1 is involved in rotenone-induced injury of PC12 cells]. | Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20120301 |
| Development and characterisation of a novel rat model of Parkinson's disease induced by sequential intranigral administration of AAV-α-synuclein and the pesticide, rotenone. | Neuroscience 20120217 |
| Brown adipose tissue mitochondria: modulation by GDP and fatty acids depends on the respiratory substrates. | Bioscience reports 20120201 |
| Protective effects of agmatine in rotenone-induced damage of human SH-SY5Y neuroblastoma cells: fourier transform infrared spectroscopy analysis in a model of Parkinson's disease. | Amino acids 20120201 |
| Different characteristics of reactive oxygen species production by human keratinocyte cell line cells in response to allergens and irritants. | Experimental dermatology 20120201 |
| Matrix metalloproteinase-3 is activated by HtrA2/Omi in dopaminergic cells: relevance to Parkinson's disease. | Neurochemistry international 20120201 |
| The mitochondrial chaperone protein TRAP1 mitigates α-Synuclein toxicity. | PLoS genetics 20120201 |
| Regulation by mitochondrial superoxide and NADPH oxidase of cellular formation of nitrated cyclic GMP: potential implications for ROS signalling. | The Biochemical journal 20120115 |
| Protective effects of baicalein against rotenone-induced neurotoxicity in PC12 cells and isolated rat brain mitochondria. | European journal of pharmacology 20120115 |
| Synthesis of deguelin-biotin conjugates and investigation into deguelin's interactions. | Bioorganic & medicinal chemistry 20120115 |
| Mitochondria-derived superoxide and voltage-gated sodium channels in baroreceptor neurons from chronic heart-failure rats. | Journal of neurophysiology 20120115 |
| Rotenone activates phagocyte NADPH oxidase by binding to its membrane subunit gp91phox. | Free radical biology & medicine 20120115 |
| [Adenovirus vector mediated human 14-3-3 γ gene transfer protects dopaminergic cells against rotenone-induced injury]. | Zhonghua yi xue za zhi 20120103 |
| Melatonin protects against rotenone-induced cell injury via inhibition of Omi and Bax-mediated autophagy in Hela cells. | Journal of pineal research 20120101 |
| Gender segregation in gene expression and vulnerability to oxidative stress induced injury in ventral mesencephalic cultures of dopamine neurons. | Journal of neuroscience research 20120101 |
| Acetyl-L-carnitine and α-lipoic acid affect rotenone-induced damage in nigral dopaminergic neurons of rat brain, implication for Parkinson's disease therapy. | Pharmacology, biochemistry, and behavior 20120101 |
| Increase of sodium delivery stimulates the mitochondrial respiratory chain H2O2 production in rat renal medullary thick ascending limb. | American journal of physiology. Renal physiology 20120101 |
| Chronic Akt blockade aggravates pathological hypertrophy and inhibits physiological hypertrophy. | American journal of physiology. Heart and circulatory physiology 20120101 |
| Reactive oxygen species are produced at low glucose and contribute to the activation of AMPK in insulin-secreting cells. | Free radical biology & medicine 20120101 |
| Tamoxifen subcellular localization; observation of cell-specific cytotoxicity enhancement by inhibition of mitochondrial ETC complexes I and III. | Photochemistry and photobiology 20120101 |
| A water soluble CoQ10 formulation improves intracellular distribution and promotes mitochondrial respiration in cultured cells. | PloS one 20120101 |
| Intestinal ischemia-reperfusion increases efflux for uric acid via paracellular route in the intestine, but decreases that via transcellular route mediated by BCRP. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20120101 |
| Real-time monitoring of superoxide generation and cytotoxicity in neuroblastoma mitochondria induced by 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline. | Redox report : communications in free radical research 20120101 |
| Deguelin attenuates reperfusion injury and improves outcome after orthotopic lung transplantation in the rat. | PloS one 20120101 |
| Mitochondria take up Ca2+ in two steps dependently on store-operated Ca2+ entry in mast cells. | Biological & pharmaceutical bulletin 20120101 |
| Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis. | PloS one 20120101 |
| Mitochondrial dysfunction and oxidative stress promote apoptotic cell death in the striatum via cytochrome c/caspase-3 signaling cascade following chronic rotenone intoxication in rats. | International journal of molecular sciences 20120101 |
| Distinct effects of rotenone, 1-methyl-4-phenylpyridinium and 6-hydroxydopamine on cellular bioenergetics and cell death. | PloS one 20120101 |
| Idebenone protects against retinal damage and loss of vision in a mouse model of Leber's hereditary optic neuropathy. | PloS one 20120101 |
| Time-dependent stabilization of hypoxia inducible factor-1α by different intracellular sources of reactive oxygen species. | PloS one 20120101 |
| Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in mice. | Scientific reports 20120101 |
| Potential autophagy enhancers attenuate rotenone-induced toxicity in SH-SY5Y. | Neuroscience 20111229 |
| Anticancer efficacy of deguelin in human prostate cancer cells targeting glycogen synthase kinase-3 β/β-catenin pathway. | International journal of cancer 20111215 |
| Neuroprotection of α-synuclein under acute and chronic rotenone and maneb treatment is abolished by its familial Parkinson's disease mutations A30P, A53T and E46K. | Neurotoxicology 20111201 |
| Reactive oxygen species-independent rapid initiation of mitochondrial apoptotic pathway by chelerythrine. | Toxicology in vitro : an international journal published in association with BIBRA 20111201 |
| Neonatal exposure to lipopolysaccharide enhances vulnerability of nigrostriatal dopaminergic neurons to rotenone neurotoxicity in later life. | Neurobiology of disease 20111201 |
| A viability assay for Candida albicans based on the electron transfer mediator 2,6-dichlorophenolindophenol. | Analytical biochemistry 20111201 |
| High efficiency of energy flux controls within mitochondrial interactosome in cardiac intracellular energetic units. | Biochimica et biophysica acta 20111201 |
| Antioxidant properties of rare sugar D-allose: Effects on mitochondrial reactive oxygen species production in Neuro2A cells. | Journal of bioscience and bioengineering 20111201 |
| Intervention of mitochondrial dysfunction-oxidative stress-dependent apoptosis as a possible neuroprotective mechanism of α-lipoic acid against rotenone-induced parkinsonism and L-dopa toxicity. | Neuroscience research 20111201 |
| Complex I and cytochrome c are molecular targets of flavonoids that inhibit hydrogen peroxide production by mitochondria. | Biochimica et biophysica acta 20111201 |
| Hypoxia acts through multiple signaling pathways to induce metallothionein transactivation by the metal-responsive transcription factor-1 (MTF-1). | Biochemistry and cell biology = Biochimie et biologie cellulaire 20111201 |
| The combination of tephrosin with 2-deoxy-D-glucose enhances the cytotoxicity via accelerating ATP depletion and blunting autophagy in human cancer cells. | Cancer biology & therapy 20111201 |
| Differential programming of p53-deficient embryonic cells during rotenone block. | Toxicology 20111128 |
| DJ-1 knock-down impairs astrocyte mitochondrial function. | Neuroscience 20111124 |
| Dopamine oxidation facilitates rotenone-dependent potentiation of N-methyl-D-aspartate currents in rat substantia nigra dopamine neurons. | Neuroscience 20111110 |
| The protective effects of inosine against chemical hypoxia on cultured rat oligodendrocytes. | Cellular and molecular neurobiology 20111101 |
| Ceruloplasmin protects against rotenone-induced oxidative stress and neurotoxicity. | Neurochemical research 20111101 |
| Environmental impact on vascular development predicted by high-throughput screening. | Environmental health perspectives 20111101 |
| Myocardial uptake of 7'-(Z)-[(123)I]iodorotenone during vasodilator stress in dogs with critical coronary stenoses. | Circulation. Cardiovascular imaging 20111101 |
| An effective novel delivery strategy of rasagiline for Parkinson's disease. | International journal of pharmaceutics 20111031 |
| Rotenone-mediated changes in intracellular coenzyme A thioester levels: implications for mitochondrial dysfunction. | Chemical research in toxicology 20111017 |
| Knock-down of argonaute 2 (AGO2) induces apoptosis in myeloid leukaemia cells and inhibits siRNA-mediated silencing of transfected oncogenes in HEK-293 cells. | Basic & clinical pharmacology & toxicology 20111001 |
| Rotenone induces degeneration of photoreceptors and impairs the dopaminergic system in the rat retina. | Neurobiology of disease 20111001 |
| Neutral sphingomyelinase, NADPH oxidase and reactive oxygen species. Role in acute hypoxic pulmonary vasoconstriction. | Journal of cellular physiology 20111001 |
| Leaf extract of Rhus verniciflua Stokes protects dopaminergic neuronal cells in a rotenone model of Parkinson's disease. | The Journal of pharmacy and pharmacology 20111001 |
| Calpain inhibition protected spinal cord motoneurons against 1-methyl-4-phenylpyridinium ion and rotenone. | Neuroscience 20110929 |
| Glyceraldehyde-3-phosphate dehydrogenase: activity inhibition and protein overexpression in rotenone models for Parkinson's disease. | Neuroscience 20110929 |
| Dose-dependent loss of motor function after unilateral medial forebrain bundle rotenone lesion in rats: a cautionary note. | Behavioural brain research 20110912 |
| Engrailed protects mouse midbrain dopaminergic neurons against mitochondrial complex I insults. | Nature neuroscience 20110904 |
| Paullinia cupana Mart. var. Sorbilis protects human dopaminergic neuroblastoma SH-SY5Y cell line against rotenone-induced cytotoxicity. | Human & experimental toxicology 20110901 |
| Assessment of newly synthesized mitochondrial DNA using BrdU labeling in primary neurons from Alzheimer's disease mice: Implications for impaired mitochondrial biogenesis and synaptic damage. | Biochimica et biophysica acta 20110901 |
| Synergistic growth inhibition of cancer cells harboring the RET/PTC1 oncogene by staurosporine and rotenone involves enhanced cell death. | Journal of biosciences 20110901 |
| Isoflurane differentially modulates mitochondrial reactive oxygen species production via forward versus reverse electron transport flow: implications for preconditioning. | Anesthesiology 20110901 |
| Microplate-based kinetic method for assay of mitochondrial NADH-- and succinate--cytochrome c reductase activities. | Analytical biochemistry 20110815 |
| Synthesis of rotenoid derivatives with cytotoxic and topoisomerase II inhibitory activities. | Bioorganic & medicinal chemistry letters 20110815 |
| Exploring the boundaries of additivity: mixtures of NADH: quinone oxidoreductase inhibitors. | Chemical research in toxicology 20110815 |
| Both stereoselective (R)- and (S)-1-Methyl-1,2,3,4-tetrahydroisoquinoline enantiomers protect striatal terminals against rotenone-induced suppression of dopamine release. | Neurotoxicity research 20110801 |
| Flavanones and rotenoids from the roots of Amorpha fruticosa L. that inhibit bacterial neuraminidase. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110801 |
| Role for pAKT in rat urinary bladder with cyclophosphamide (CYP)-induced cystitis. | American journal of physiology. Renal physiology 20110801 |
| Resveratrol-activated AMPK/SIRT1/autophagy in cellular models of Parkinson's disease. | Neuro-Signals 20110801 |
| Oxygen consumption rate of permeabilized cells and isolated mitochondria from pork M. masseter and liver examined fresh and after freeze-thawing at different pH values. | Journal of food science 20110801 |
| Effects of pioglitazone and retinoic acid in a rotenone model of Parkinson's disease. | Brain research bulletin 20110715 |
| Insecticidal effect and chemical composition of the volatile oil from Bergenia ligulata. | Journal of agricultural and food chemistry 20110713 |
| Relative contributions of mitochondria and NADPH oxidase to deoxycorticosterone acetate-salt hypertension in mice. | Kidney international 20110701 |
| Antifeedant effect of commercial chemicals and plant extracts against Schistocerca americana (Orthoptera: Acrididae) and Diaprepes abbreviatus (Coleoptera: Curculionidae). | Pest management science 20110701 |
| Role of cAMP-responsive element-binding protein (CREB)-regulated transcription coactivator 3 (CRTC3) in the initiation of mitochondrial biogenesis and stress response in liver cells. | The Journal of biological chemistry 20110624 |
| Mitochondrial uncoupling agents antagonize rotenone actions in rat substantia nigra dopamine neurons. | Brain research 20110613 |
| High-mobility group box 1 is essential for mitochondrial quality control. | Cell metabolism 20110608 |
| Effect of mitochondrial complex I inhibition on Fe-S cluster protein activity. | Biochemical and biophysical research communications 20110603 |
| Multi-walled carbon nanotubes induce oxidative stress and apoptosis in human lung cancer cell line-A549. | Nanotoxicology 20110601 |
| Rotenone, paraquat, and Parkinson's disease. | Environmental health perspectives 20110601 |
| Glucose metabolism in mouse cumulus cells prevents oocyte aging by maintaining both energy supply and the intracellular redox potential. | Biology of reproduction 20110601 |
| PARK6 PINK1 mutants are defective in maintaining mitochondrial membrane potential and inhibiting ROS formation of substantia nigra dopaminergic neurons. | Biochimica et biophysica acta 20110601 |
| Human space exploration the next fifty years. | McGill journal of medicine : MJM : an international forum for the advancement of medical sciences by students 20110601 |
| Functional relevance of the histone gammaH2Ax in the response to DNA damaging agents. | Proceedings of the National Academy of Sciences of the United States of America 20110524 |
| Mitochondrial complex I impairment in leukocytes from type 2 diabetic patients. | Free radical biology & medicine 20110515 |
| Alternative mitochondrial electron transfer as a novel strategy for neuroprotection. | The Journal of biological chemistry 20110506 |
| Characterisation of a novel model of Parkinson's disease by intra-striatal infusion of the pesticide rotenone. | Neuroscience 20110505 |
| DJ-1 deficiency in astrocytes selectively enhances mitochondrial Complex I inhibitor-induced neurotoxicity. | Journal of neurochemistry 20110501 |
| Impaired CD200-CD200R-mediated microglia silencing enhances midbrain dopaminergic neurodegeneration: roles of aging, superoxide, NADPH oxidase, and p38 MAPK. | Free radical biology & medicine 20110501 |
| Dopamine D₁ and D₂ receptor subtypes functional regulation in cerebral cortex of unilateral rotenone lesioned Parkinson's rat model: Effect of serotonin, dopamine and norepinephrine. | Parkinsonism & related disorders 20110501 |
| Reactive oxygen species (ROS) play a critical role in the cAMP-induced activation of Ras and the phosphorylation of ERK1/2 in Leydig cells. | Molecular endocrinology (Baltimore, Md.) 20110501 |
| Aminoethoxydiphenyl borate and flufenamic acid inhibit Ca2+ influx through TRPM2 channels in rat dorsal root ganglion neurons activated by ADP-ribose and rotenone. | The Journal of membrane biology 20110501 |
| [Effects of deguelin on proliferation and apoptosis of MCF-7 breast cancer cells by phosphatidylinositol 3-kinase/Akt signaling pathway]. | Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20110501 |
| Pierreiones A-D, solid tumor selective pyranoisoflavones and other cytotoxic constituents from Antheroporum pierrei. | Journal of natural products 20110425 |
| EPR detection of cellular and mitochondrial superoxide using cyclic hydroxylamines. | Free radical research 20110401 |
| Equol-stimulated mitochondrial reactive oxygen species activate endothelial nitric oxide synthase and redox signaling in endothelial cells: roles for F-actin and GPR30. | Hypertension (Dallas, Tex. : 1979) 20110401 |
| Variable responses of small and large human hepatocytes to hypoxia and hypoxia/reoxygenation (H-R). | FEBS letters 20110323 |
| Over-expression of α-synuclein 98 triggers intracellular oxidative stress and enhances susceptibility to rotenone. | Neuroscience letters 20110317 |
| Estrogen protection against mitochondrial toxin-induced cell death in hippocampal neurons: antagonism by progesterone. | Brain research 20110316 |
| Loss of caspase-2-dependent apoptosis induces autophagy after mitochondrial oxidative stress in primary cultures of young adult cortical neurons. | The Journal of biological chemistry 20110311 |
| Loss of mitochondrial complex I activity potentiates dopamine neuron death induced by microtubule dysfunction in a Parkinson's disease model. | The Journal of cell biology 20110307 |
| Detoxified extract of Rhus verniciflua stokes inhibits rotenone-induced apoptosis in human dopaminergic cells, SH-SY5Y. | Cellular and molecular neurobiology 20110301 |
| Enhanced formation of methane in plant cell cultures by inhibition of cytochrome c oxidase. | Plant, cell & environment 20110301 |
| Differential contribution of mitochondria, NADPH oxidases, and glycolysis to region-specific oxidant stress in the anoxic-reoxygenated embryonic heart. | American journal of physiology. Heart and circulatory physiology 20110301 |
| Fructose induces gluconeogenesis and lipogenesis through a SIRT1-dependent mechanism. | The Journal of endocrinology 20110301 |
| Involvement of p53 in cell death following cell cycle arrest and mitotic catastrophe induced by rotenone. | Biochimica et biophysica acta 20110301 |
| [Rotenone-induced changes of cysteinyl leukotriene receptor 1 expression in BV2 microglial cells]. | Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20110301 |
| [5-lipoxygenase is involved in rotenone-induced injury in PC12 cells]. | Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20110301 |
| 'Metabolic reprogramming' in ovarian cancer cells resistant to cisplatin. | Current cancer drug targets 20110201 |
| The role of mitochondria in the radiation-induced bystander effect in human lymphoblastoid cells. | Radiation research 20110201 |
| Effect of exposure to the edge signal on oxidative stress in brain cell models. | Radiation research 20110201 |
| Human dental pulp stem cells protect mouse dopaminergic neurons against MPP+ or rotenone. | Brain research 20110107 |
| Metformin activates AMP kinase through inhibition of AMP deaminase. | The Journal of biological chemistry 20110107 |
| Reversal of rotenone-induced dysfunction of astrocytic connexin43 by opening mitochondrial ATP-sensitive potassium channels. | Cellular and molecular neurobiology 20110101 |
| Activation of STAT1 is required for interferon-alpha-mediated cell death. | Experimental cell research 20110101 |
| DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy. | Human molecular genetics 20110101 |
| Agmatine effects on mitochondrial membrane potential and NF-κB activation protect against rotenone-induced cell damage in human neuronal-like SH-SY5Y cells. | Journal of neurochemistry 20110101 |
| Hydrogel tissue construct-based high-content compound screening. | Journal of biomolecular screening 20110101 |
| Parkinsonian rotenone mouse model: reevaluation of long-term administration of rotenone in C57BL/6 mice. | Biological & pharmaceutical bulletin 20110101 |
| Neoechinulin a impedes the progression of rotenone-induced cytotoxicity in PC12 cells. | Biological & pharmaceutical bulletin 20110101 |
| BmDJ-1 is a key regulator of oxidative modification in the development of the silkworm, Bombyx mori. | PloS one 20110101 |
| NQO1-dependent redox cycling of idebenone: effects on cellular redox potential and energy levels. | PloS one 20110101 |
| Effect of malate on the development of rotenone-induced brain changes in Wistar and OXYS rats: An MRI study. | Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20110101 |
| Paraquat- and rotenone-induced models of Parkinson's disease. | International journal of immunopathology and pharmacology 20110101 |
| Edaravone guards dopamine neurons in a rotenone model for Parkinson's disease. | PloS one 20110101 |
| 14-3-3theta protects against neurotoxicity in a cellular Parkinson's disease model through inhibition of the apoptotic factor Bax. | PloS one 20110101 |
| Characterization of the stimulus for reactive oxygen species generation in calcium-overloaded mitochondria. | Redox report : communications in free radical research 20110101 |
| JNK3-mediated apoptotic cell death in primary dopaminergic neurons. | Methods in molecular biology (Clifton, N.J.) 20110101 |
| Fluorescence dequenching makes haem-free soluble guanylate cyclase detectable in living cells. | PloS one 20110101 |
| [Regulation of the mitochondrial ATP-sensitive potassium channel in rat uterus cells by ROS]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20110101 |
| High-density real-time PCR-based in vivo toxicogenomic screen to predict organ-specific toxicity. | International journal of molecular sciences 20110101 |
| Protection against dopaminergic neurodegeneration in Parkinson's disease-model animals by a modulator of the oxidized form of DJ-1, a wild-type of familial Parkinson's disease-linked PARK7. | Journal of pharmacological sciences 20110101 |
| The automated FADU-assay, a potential high-throughput in vitro method for early screening of DNA breakage. | ALTEX 20110101 |
| Development of a high-throughput screening assay for cytoprotective agents in rotenone-induced cell death. | Analytical biochemistry 20101215 |
| Free tubulin modulates mitochondrial membrane potential in cancer cells. | Cancer research 20101215 |
| New insights into the superoxide generation sites in bovine heart NADH-ubiquinone oxidoreductase (Complex I): the significance of protein-associated ubiquinone and the dynamic shifting of generation sites between semiflavin and semiquinone radicals. | Biochimica et biophysica acta 20101201 |
| A predictive ligand-based Bayesian model for human drug-induced liver injury. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
| Energetic metabolism and human sperm motility: impact of CB₁ receptor activation. | Endocrinology 20101201 |
| Effects of rotenone and other mitochondrial complex I inhibitors on the brine shrimp Artemia. | Acta biologica Hungarica 20101201 |
| Deguelin--an inhibitor to tumor lymphangiogenesis and lymphatic metastasis by downregulation of vascular endothelial cell growth factor-D in lung tumor model. | International journal of cancer 20101115 |
| Progressive loss of dopaminergic neurons induced by unilateral rotenone infusion into the medial forebrain bundle. | Brain research 20101111 |
| Long-term efficacy and safety of human umbilical cord mesenchymal stromal cells in rotenone-induced hemiparkinsonian rats. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20101101 |
| Qo site of mitochondrial complex III is the source of increased superoxide after transient exposure to hydrogen peroxide. | Journal of molecular and cellular cardiology 20101101 |
| Rotenoids from Lablab purpureus L. and their bioefficacy against human disease vectors. | Parasitology research 20101101 |
| Dopamine D₁ and D₂ receptor subtypes functional regulation in corpus striatum of unilateral rotenone lesioned Parkinson's rat model: effect of serotonin, dopamine and norepinephrine. | Neurological research 20101101 |
| Role of mitochondria in contraction and pacemaking in the mouse uterus. | British journal of pharmacology 20101101 |
| Tephrosin-induced autophagic cell death in A549 non-small cell lung cancer cells. | Journal of Asian natural products research 20101101 |
| Dopamine-dependent neurodegeneration in Drosophila models of familial and sporadic Parkinson's disease. | Neurobiology of disease 20101001 |
| Phenothiazines interfere with dopaminergic neurodegeneration in Caenorhabditis elegans models of Parkinson's disease. | Neurobiology of disease 20101001 |
| α-Synuclein transgenic mice reveal compensatory increases in Parkinson's disease-associated proteins DJ-1 and parkin and have enhanced α-synuclein and PINK1 levels after rotenone treatment. | Journal of molecular neuroscience : MN 20101001 |
| Neuroprotection of deferoxamine on rotenone-induced injury via accumulation of HIF-1 alpha and induction of autophagy in SH-SY5Y cells. | Neurochemistry international 20101001 |
| Impaired 3',5'-cyclic adenosine monophosphate-mediated signaling in immediate early responsive gene X-1-deficient vascular smooth muscle cells. | Hypertension (Dallas, Tex. : 1979) 20101001 |
| Deguelin promotes apoptosis and inhibits angiogenesis of gastric cancer. | Oncology reports 20101001 |
| Effects of rotenone and pyridaben on complex I electron transfer and on mitochondrial nitric oxide synthase functional activity. | Journal of bioenergetics and biomembranes 20101001 |
| Glutamine-mediated protection from neuronal cell death depends on mitochondrial activity. | Neuroscience letters 20100927 |
| Attenuation of rotenone-induced mitochondrial oxidative damage and neurotoxicty in Drosophila melanogaster supplemented with creatine. | Neurochemical research 20100901 |
| Association of dopamine DA-D2 receptor in rotenone-induced cytotoxicity in PC12 cells. | Toxicology and industrial health 20100901 |
| [Some bio-chemical indice change of rats striatum poisoned by rotenone]. | Wei sheng yan jiu = Journal of hygiene research 20100901 |
| Concise modular asymmetric synthesis of deguelin, tephrosin and investigation into their mode of action. | Chemistry (Weinheim an der Bergstrasse, Germany) 20100823 |
| Depressive-like behaviors alterations induced by intranigral MPTP, 6-OHDA, LPS and rotenone models of Parkinson's disease are predominantly associated with serotonin and dopamine. | Progress in neuro-psychopharmacology & biological psychiatry 20100816 |
| Transgenic mice overexpressing methionine sulfoxide reductase A: characterization of embryonic fibroblasts. | Free radical biology & medicine 20100815 |
| The marine sponge metabolite mycothiazole: a novel prototype mitochondrial complex I inhibitor. | Bioorganic & medicinal chemistry 20100815 |
| Respiration in adipocytes is inhibited by reactive oxygen species. | Obesity (Silver Spring, Md.) 20100801 |
| Rotenone prevents impact-induced chondrocyte death. | Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20100801 |
| Oxidation of hydrogen sulfide remains a priority in mammalian cells and causes reverse electron transfer in colonocytes. | Biochimica et biophysica acta 20100801 |
| [Separation and preparation of two rotenoids from the roots of Derris by high-speed counter-current chromatography]. | Se pu = Chinese journal of chromatography 20100801 |
| Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives. | Journal of medicinal chemistry 20100722 |
| Tephrosin induces internalization and degradation of EGFR and ErbB2 in HT-29 human colon cancer cells. | Cancer letters 20100701 |
| Hexokinase II gene transfer protects against neurodegeneration in the rotenone and MPTP mouse models of Parkinson's disease. | Journal of neuroscience research 20100701 |
| Losartan improved respiratory function and coenzyme Q content in brain mitochondria of young spontaneously hypertensive rats. | Cellular and molecular neurobiology 20100701 |
| Rho kinase activation and ROS production contributes to the cooling enhanced contraction in cutaneous equine digital veins. | Journal of applied physiology (Bethesda, Md. : 1985) 20100701 |
| Ketones prevent synaptic dysfunction induced by mitochondrial respiratory complex inhibitors. | Journal of neurochemistry 20100701 |
| 4-Nitrobenzoate inhibits coenzyme Q biosynthesis in mammalian cell cultures. | Nature chemical biology 20100701 |
| [Protective effect of over-expression OGCP on HEK293 cells treated by rotenone and mutant Parkin protein]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20100701 |
| Mammalian mitochondrial complex I: biogenesis, regulation, and reactive oxygen species generation. | Antioxidants & redox signaling 20100615 |
| A study to correlate rotenone induced biochemical changes and cerebral damage in brain areas with neuromuscular coordination in rats. | Toxicology 20100604 |
| Mitochondrial development and the influence of its dysfunction during rat adipocyte differentiation. | Molecular biology reports 20100601 |
| Rotenone enhances the antifungal properties of staurosporine. | Eukaryotic cell 20100601 |
| Albumin uptake in OK cells exposed to rotenone: a model for studying the effects of mitochondrial dysfunction on endocytosis in the proximal tubule? | Nephron. Physiology 20100601 |
| Measurement of intrinsic physiological membrane noise in cultured living cells. | Electromagnetic biology and medicine 20100601 |
| The alternative medicine pawpaw and its acetogenin constituents suppress tumor angiogenesis via the HIF-1/VEGF pathway. | Journal of natural products 20100528 |
| Photolabile ubiquinone analogues for identification and characterization of quinone binding sites in proteins. | Bioorganic & medicinal chemistry 20100515 |
| Synthesis and evaluation of verticipyrone analogues as mitochondrial complex I inhibitors. | Bioorganic & medicinal chemistry 20100515 |
| Chronic administration with rotenone does not enhance MPTP neurotoxicity in C57BL/6 mice. | Journal of molecular neuroscience : MN 20100501 |
| Cytochrome c is rapidly reduced in the cytosol after mitochondrial outer membrane permeabilization. | Apoptosis : an international journal on programmed cell death 20100501 |
| Molecular mechanisms of methylmercury-induced cell death in human HepG2 cells. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100501 |
| Bioactivity-guided isolation of mosquitocidal constituents from the rhizomes of Plumbago capensis Thunb. | Bioorganic & medicinal chemistry letters 20100501 |
| JNK3 mediates paraquat- and rotenone-induced dopaminergic neuron death. | Journal of neuropathology and experimental neurology 20100501 |
| Dual effects of alpha-synuclein on neurotoxicity induced by low dosage of rotenone are dependent on exposure time in dopaminergic neuroblastoma cells. | Science China. Life sciences 20100501 |
| Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes. | Circulation research 20100416 |
| Neuroprotective effects of hydrogen sulfide on Parkinson's disease rat models. | Aging cell 20100401 |
| Hypoxia sensing in the fetal chicken femoral artery is mediated by the mitochondrial electron transport chain. | American journal of physiology. Regulatory, integrative and comparative physiology 20100401 |
| Energy conservation by Rhodothermus marinus respiratory complex I. | Biochimica et biophysica acta 20100401 |
| Decylubiquinone increases mitochondrial function in synaptosomes. | The Journal of biological chemistry 20100319 |
| Reactive oxygen species (ROS) in the human neocortex: role of aging and cognition. | Brain research bulletin 20100316 |
| Gene therapy using lactoferrin-modified nanoparticles in a rotenone-induced chronic Parkinson model. | Journal of the neurological sciences 20100315 |
| Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA's ToxCast program. | Chemical research in toxicology 20100315 |
| Autophagy protects the rotenone-induced cell death in alpha-synuclein overexpressing SH-SY5Y cells. | Neuroscience letters 20100312 |
| Mitochondrial dysfunction enhances the migration of vascular smooth muscles cells via suppression of Akt phosphorylation. | Biochimica et biophysica acta 20100301 |
| Deguelin suppresses cell proliferation via the inhibition of survivin expression and STAT3 phosphorylation in HTLV-1-transformed T cells. | Leukemia research 20100301 |
| Inhibition of osteoclast differentiation and bone resorption by rotenone, through down-regulation of RANKL-induced c-Fos and NFATc1 expression. | Bone 20100301 |
| The pattern of neuronal loss and survival may reflect differential expression of proteasome activators in Parkinson's disease. | Synapse (New York, N.Y.) 20100301 |
| Oligodendroglial differentiation induces mitochondrial genes and inhibition of mitochondrial function represses oligodendroglial differentiation. | Mitochondrion 20100301 |
| Carnosine protects against permanent cerebral ischemia in histidine decarboxylase knockout mice by reducing glutamate excitotoxicity. | Free radical biology & medicine 20100301 |
| MKK6 binds and regulates expression of Parkinson's disease-related protein LRRK2. | Journal of neurochemistry 20100301 |
| Mitochondrial p32 protein is a critical regulator of tumor metabolism via maintenance of oxidative phosphorylation. | Molecular and cellular biology 20100301 |
| Dexamethasone and the inflammatory response in explants of human omental adipose tissue. | Molecular and cellular endocrinology 20100205 |
| Valproic acid is neuroprotective in the rotenone rat model of Parkinson's disease: involvement of alpha-synuclein. | Neurotoxicity research 20100201 |
| Melatonin treatment potentiates neurodegeneration in a rat rotenone Parkinson's disease model. | Journal of neuroscience research 20100201 |
| Rotenone induces apoptosis in MCF-7 human breast cancer cell-mediated ROS through JNK and p38 signaling. | Molecular carcinogenesis 20100201 |
| Oxidants induce alternative splicing of alpha-synuclein: Implications for Parkinson's disease. | Free radical biology & medicine 20100201 |
| Enhanced metallothionein gene expression induced by mitochondrial oxidative stress is reduced in phospholipid hydroperoxide glutathione peroxidase-overexpressed cells. | European journal of pharmacology 20100125 |
| Synphilin-1 exhibits trophic and protective effects against Rotenone toxicity. | Neuroscience 20100120 |
| Comparison of methods for measuring oxygen consumption in tumor cells in vitro. | Analytical biochemistry 20100115 |
| Effects of epigallocatechin gallate on rotenone-injured murine brain cultures. | Journal of neural transmission (Vienna, Austria : 1996) 20100101 |
| In vitro cell-toxicity screening as an alternative animal model for coral toxicology: effects of heat stress, sulfide, rotenone, cyanide, and cuprous oxide on cell viability and mitochondrial function. | Ecotoxicology (London, England) 20100101 |
| Electrophysiological actions of zonisamide on striatal neurons: Selective neuroprotection against complex I mitochondrial dysfunction. | Experimental neurology 20100101 |
| Impairment of mitochondrial respiration in mouse fibroblasts by oncogenic H-RAS(Q61L). | Cancer biology & therapy 20100101 |
| The effect of antiparkinsonian drugs on oxidative stress induced pathological [3H]dopamine efflux after in vitro rotenone exposure in rat striatal slices. | Neuropharmacology 20100101 |
| The role of the Akt/mTOR pathway in tobacco carcinogen-induced lung tumorigenesis. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100101 |
| Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models. | Disease models & mechanisms 20100101 |
| Progression of Parkinson's disease pathology is reproduced by intragastric administration of rotenone in mice. | PloS one 20100101 |
| Minocycline protects dopaminergic neurons against long-term rotenone toxicity. | The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20100101 |
| Fusion of the endoplasmic reticulum and mitochondrial outer membrane in rats brown adipose tissue: activation of thermogenesis by Ca2+. | PloS one 20100101 |
| Disruption of astrocyte STAT3 signaling decreases mitochondrial function and increases oxidative stress in vitro. | PloS one 20100101 |
| Combined R-alpha-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson's disease. | Journal of cellular and molecular medicine 20100101 |
| Animal models of neurological disease. | Advances in experimental medicine and biology 20100101 |
| Successful amelioration of mitochondrial optic neuropathy using the yeast NDI1 gene in a rat animal model. | PloS one 20100101 |
| Effects of mitochondrial dysfunction on the immunological properties of microglia. | Journal of neuroinflammation 20100101 |
| Neurotoxic in vivo models of Parkinson's disease recent advances. | Progress in brain research 20100101 |
| Protein aggregation containing β-amyloid, α-synuclein and hyperphosphorylated τ in cultured cells of hippocampus, substantia nigra and locus coeruleus after rotenone exposure. | BMC neuroscience 20100101 |
| Differential neuroprotective effects of 14-3-3 proteins in models of Parkinson's disease. | Cell death & disease 20100101 |
| HDAC inhibitor trichostatin A-inhibited survival of dopaminergic neuronal cells. | Neuroscience letters 20091231 |
| Rotenone induces cell death of cholinergic neurons in an organotypic co-culture brain slice model. | Neurochemical research 20091201 |
| An integrated cellular model to evaluate cytotoxic effects in mammalian cell lines. | Toxicology in vitro : an international journal published in association with BIBRA 20091201 |
| Neuroprotective effect of the antiparkinsonian drug pramipexole against nigrostriatal dopaminergic degeneration in rotenone-treated mice. | Neurochemistry international 20091201 |
| Rapamycin protects against rotenone-induced apoptosis through autophagy induction. | Neuroscience 20091201 |
| Evidence for aerobic metabolism in retinal rod outer segment disks. | The international journal of biochemistry & cell biology 20091201 |
| Conditional knockout of Mn-SOD targeted to type IIB skeletal muscle fibers increases oxidative stress and is sufficient to alter aerobic exercise capacity. | American journal of physiology. Cell physiology 20091201 |
| Isotope dilution method for the assay of rotenone in olive oil and river waters by liquid chromatography/multiple reaction monitoring tandem mass spectrometry. | Rapid communications in mass spectrometry : RCM 20091201 |
| Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease. | Human molecular genetics 20091115 |
| Effect of centrophenoxine against rotenone-induced oxidative stress in an animal model of Parkinson's disease. | Neurochemistry international 20091101 |
| Protective effect of histamine H2 receptor antagonist ranitidine against rotenone-induced apoptosis. | Neurotoxicology 20091101 |
| Neuroprotective efficacy of Bacopa monnieri against rotenone induced oxidative stress and neurotoxicity in Drosophila melanogaster. | Neurotoxicology 20091101 |
| Rapid flow cytometric method for measuring senescence associated beta-galactosidase activity in human fibroblasts. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20091101 |
| Pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione derivatives: their cytoprotection effect from rotenone toxicity and preliminary DMPK properties. | Bioorganic & medicinal chemistry letters 20091101 |
| Deguelin inhibits growth of breast cancer cells by modulating the expression of key members of the Wnt signaling pathway. | Cancer prevention research (Philadelphia, Pa.) 20091101 |
| A novel look into estrogen receptor-negative breast cancer prevention with the natural, multifunctional signal transduction inhibitor deguelin. | Cancer prevention research (Philadelphia, Pa.) 20091101 |
| Acute action of rotenone on nigral dopaminergic neurons--involvement of reactive oxygen species and disruption of Ca2+ homeostasis. | The European journal of neuroscience 20091101 |
| Induction of heat shock protein 70 reduces the alteration of striatal electrical activity caused by mitochondrial impairment. | Neuroscience 20091020 |
| Metformin suppresses glucose-6-phosphatase expression by a complex I inhibition and AMPK activation-independent mechanism. | Biochemical and biophysical research communications 20091016 |
| Effects of glutamate and alpha2-noradrenergic receptor antagonists on the development of neurotoxicity produced by chronic rotenone in rats. | Toxicology and applied pharmacology 20091015 |
| Deleterious versus neuroprotective effect of metabolic inhibition after traumatic spinal cord injury. | Spinal cord 20091001 |
| Rotenone partially reverses decreased BK Ca currents in cerebral artery smooth muscle cells from streptozotocin-induced diabetic mice. | Clinical and experimental pharmacology & physiology 20091001 |
| Metabolic control analysis in a cellular model of elevated MAO-B: relevance to Parkinson's disease. | Neurotoxicity research 20091001 |
| Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. | Nature chemical biology 20091001 |
| Reactive oxygen species potentiate the P2X2 receptor activity through intracellular Cys430. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090930 |
| Hypoxia up-regulates CD36 expression and function via hypoxia-inducible factor-1- and phosphatidylinositol 3-kinase-dependent mechanisms. | The Journal of biological chemistry 20090925 |
| A novel decoy that interrupts G93A-superoxide dismutase gain of interaction with malate dehydrogenase improves survival in an amyotrophic lateral sclerosis cell model. | Journal of medicinal chemistry 20090910 |
| Parkin protects against LRRK2 G2019S mutant-induced dopaminergic neurodegeneration in Drosophila. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090909 |
| Direct, real-time monitoring of superoxide generation in isolated mitochondria. | Free radical research 20090901 |
| Environmental toxins and Parkinson's disease: what have we learned from pesticide-induced animal models? | Trends in pharmacological sciences 20090901 |
| Dermal fibroblasts from long-lived Ames dwarf mice maintain their in vivo resistance to mitochondrial generated reactive oxygen species (ROS). | Aging 20090901 |
| Neurons express hemoglobin alpha- and beta-chains in rat and human brains. | The Journal of comparative neurology 20090810 |
| Tranexamic acid protects against rotenone-induced apoptosis in human neuroblastoma SH-SY5Y cells. | Toxicology 20090803 |
| Mitochondrial calcium transport and mitochondrial dysfunction after global brain ischemia in rat hippocampus. | Neurochemical research 20090801 |
| Pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione derivatives as novel small molecule chaperone amplifiers. | Bioorganic & medicinal chemistry letters 20090801 |
| Hypoxia induces B-type natriuretic peptide release in cell lines derived from human cardiomyocytes. | American journal of physiology. Heart and circulatory physiology 20090801 |
| Rapid analysis of organic farming insecticides in soil and produce using ultra-performance liquid chromatography/tandem mass spectrometry. | Analytical and bioanalytical chemistry 20090801 |
| Metabolic activity determines efficacy of macroautophagic clearance of pathological oligomeric alpha-synuclein. | The American journal of pathology 20090801 |
| Reactive oxygen species and p38 mitogen-activated protein kinase induce apoptotic death of U937 cells in response to Naja nigricollis toxin-gamma. | Journal of cellular and molecular medicine 20090801 |
| LRRK2 modulates vulnerability to mitochondrial dysfunction in Caenorhabditis elegans. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090722 |
| Pigment epithelium derived factor (PEDF) is neuroprotective in two in vitro models of Parkinson's disease. | Neuroscience letters 20090717 |
| Protected cyanohydrins in the synthesis of rotenoids: (+/-)-munduserone and (+/-)-cis-12a-hydroxymunduserone. | The Journal of organic chemistry 20090717 |
| Mitochondria are the source of hydrogen peroxide for dynamic brain-cell signaling. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090715 |
| Involvement of glyceraldehyde-3-phosphate dehydrogenase in rotenone-induced cell apoptosis: relevance to protein misfolding and aggregation. | Brain research 20090707 |
| Vascular pathology in male Lewis rats following short-term, low-dose rotenone administration. | Veterinary pathology 20090701 |
| Gene expression profiling identifies a role for CHOP during inhibition of the mitochondrial respiratory chain. | Journal of biochemistry 20090701 |
| Antifeedant activity of ethanolic extract from Flourensia oolepis and isolation of pinocembrin as its active principle compound. | Bioresource technology 20090701 |
| Delayed gastric emptying and enteric nervous system dysfunction in the rotenone model of Parkinson's disease. | Experimental neurology 20090701 |
| Mitochondrial electron transport chain blockers enhance 2-deoxy-D-glucose induced oxidative stress and cell killing in human colon carcinoma cells. | Cancer biology & therapy 20090701 |
| Combining 2-deoxy-D-glucose with electron transport chain blockers: a double-edged sword. | Cancer biology & therapy 20090701 |
| Behavioral and quantitative mitochondrial proteome analyses of the effects of simvastatin: implications for models of neural degeneration. | Journal of neural transmission (Vienna, Austria : 1996) 20090701 |
| Environmental toxicants inhibit neuronal Jak tyrosine kinase by mitochondrial disruption. | Neurotoxicology 20090701 |
| Terretonins E and F, inhibitors of the mitochondrial respiratory chain from the marine-derived fungus Aspergillus insuetus (#). | Journal of natural products 20090701 |
| Tyrosine hydroxylase-positive amacrine interneurons in the mouse retina are resistant against the application of various parkinsonian toxins. | Brain research bulletin 20090630 |
| Oxygen sensitivity of mitochondrial reactive oxygen species generation depends on metabolic conditions. | The Journal of biological chemistry 20090612 |
| Cyclo(His-Pro) promotes cytoprotection by activating Nrf2-mediated up-regulation of antioxidant defence. | Journal of cellular and molecular medicine 20090601 |
| A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease. | Neurobiology of disease 20090601 |
| Mitochondrial impacts of insecticidal formate esters in insecticide-resistant and insecticide-susceptible Drosophila melanogaster. | Pest management science 20090601 |
| Involvement of SRC-3 in deguelin-induced apoptosis in Jurkat cells. | International journal of hematology 20090601 |
| Deguelin blocks cells survival signal pathways and induces apoptosis of HL-60 cells in vitro. | International journal of hematology 20090601 |
| Glutathione S-transferase pi localizes in mitochondria and protects against oxidative stress. | Free radical biology & medicine 20090515 |
| Differential effects of mitochondrial Complex I inhibitors on production of reactive oxygen species. | Biochimica et biophysica acta 20090501 |
| Thymoquinone protects dopaminergic neurons against MPP+ and rotenone. | Phytotherapy research : PTR 20090501 |
| Inhibition of mitochondrial function induces an integrated stress response in oligodendroglia. | Neurobiology of disease 20090501 |
| Effects of aerobic and anaerobic metabolic inhibitors on avian intrapulmonary chemoreceptors. | American journal of physiology. Regulatory, integrative and comparative physiology 20090501 |
| Monitoring the in vivo redox state of plant mitochondria: effect of respiratory inhibitors, abiotic stress and assessment of recovery from oxidative challenge. | Biochimica et biophysica acta 20090501 |
| A highly reproducible rotenone model of Parkinson's disease. | Neurobiology of disease 20090501 |
| A2A adenosine receptor antagonists protect the striatum against rotenone-induced neurotoxicity. | Experimental neurology 20090501 |
| Modulation of connexin 43 in rotenone-induced model of Parkinson's disease. | Neuroscience 20090421 |
| Assembly of a chimeric respiratory chain from bovine heart submitochondrial particles and cytochrome bd terminal oxidase of Escherichia coli. | FEBS letters 20090417 |
| Protective effects of asiatic acid on rotenone- or H2O2-induced injury in SH-SY5Y cells. | Neurochemical research 20090401 |
| Toxicological assessment of chemicals using Caenorhabditis elegans and optical oxygen respirometry. | Environmental toxicology and chemistry 20090401 |
| Mitochondria-derived reactive oxygen species mediate heme oxygenase-1 expression in sheared endothelial cells. | The Journal of pharmacology and experimental therapeutics 20090401 |
| Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation. | Nature chemical biology 20090401 |
| Liposomal encapsulation of deguelin: evidence for enhanced antitumor activity in tobacco carcinogen-induced and oncogenic K-ras-induced lung tumorigenesis. | Cancer prevention research (Philadelphia, Pa.) 20090401 |
| Forensic studies of brain vulnerability and resistance: ischemia-induced dopamine and serotonin releases in the rat nucleus accumbens. | Legal medicine (Tokyo, Japan) 20090401 |
| Methylene blue provides behavioral and metabolic neuroprotection against optic neuropathy. | Neurotoxicity research 20090401 |
| Residues of rotenone, azadirachtin, pyrethrins and copper used to control Bactrocera oleae (Gmel.) in organic olives and oil. | Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20090401 |
| Reduction of hydrophilic ubiquinones by the flavin in mitochondrial NADH:ubiquinone oxidoreductase (Complex I) and production of reactive oxygen species. | Biochemistry 20090310 |
| Keap1/Nrf2 system regulates neuronal survival as revealed through study of keap1 gene-knockout mice. | Biochemical and biophysical research communications 20090306 |
| Proteasomal inhibition reduces parkin mRNA in PC12 and SH-SY5Y cells. | Parkinsonism & related disorders 20090301 |
| Inhibitory modulation of the mitochondrial permeability transition by minocycline. | Biochemical pharmacology 20090301 |
| Inhibitory vs. protective effects of N-acetyl-l-cysteine (NAC) on the electromechanical properties of the spontaneously beating atria of the frog (Rana ridibunda): an ex vivo study. | Toxicology in vitro : an international journal published in association with BIBRA 20090301 |
| Nicotinic receptor-mediated neuroprotection in neurodegenerative disease models. | Biological & pharmaceutical bulletin 20090301 |
| Rotenone reduces Mg2+-dependent block of NMDA currents in substantia nigra dopamine neurons. | Neurotoxicology 20090301 |
| Methylalpinumisoflavone inhibits hypoxia-inducible factor-1 (HIF-1) activation by simultaneously targeting multiple pathways. | The Journal of biological chemistry 20090227 |
| Effects of lactate on beef heart mitochondrial oxygen consumption and muscle darkening. | Journal of agricultural and food chemistry 20090225 |
| Analysis of targeted mutation in DJ-1 on cellular function in primary astrocytes. | Toxicology letters 20090210 |
| Parkin protects dopaminergic neurons against microtubule-depolymerizing toxins by attenuating microtubule-associated protein kinase activation. | The Journal of biological chemistry 20090206 |
| Nicotinic receptor stimulation protects nigral dopaminergic neurons in rotenone-induced Parkinson's disease models. | Journal of neuroscience research 20090201 |
| Low dose rotenone treatment causes selective transcriptional activation of cell death related pathways in dopaminergic neurons in vivo. | Neurobiology of disease 20090201 |
| Type II NADH dehydrogenase of the respiratory chain of Plasmodium falciparum and its inhibitors. | Bioorganic & medicinal chemistry letters 20090201 |
| The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha. | Journal of neurochemistry 20090201 |
| Reactive oxygen species regulate ceruloplasmin by a novel mRNA decay mechanism involving its 3'-untranslated region: implications in neurodegenerative diseases. | The Journal of biological chemistry 20090116 |
| Oxidative and inflammatory pathways in Parkinson's disease. | Neurochemical research 20090101 |
| Superoxide and respiratory coupling in mitochondria of insulin-deficient diabetic rats. | Endocrinology 20090101 |
| Hydrogen sulfide inhibits rotenone-induced apoptosis via preservation of mitochondrial function. | Molecular pharmacology 20090101 |
| Role of mitochondrial oxidative stress in the apoptosis induced by diospyrin diethylether in human breast carcinoma (MCF-7) cells. | Molecular and cellular biochemistry 20090101 |
| DJ-1 knock-down in astrocytes impairs astrocyte-mediated neuroprotection against rotenone. | Neurobiology of disease 20090101 |
| Catalpol attenuates nitric oxide increase via ERK signaling pathways induced by rotenone in mesencephalic neurons. | Neurochemistry international 20090101 |
| Induction of Arabidopsis gdh2 gene expression during changes in redox state of the mitochondrial respiratory chain. | Biochemistry. Biokhimiia 20090101 |
| Pro-oxidant mitochondrial matrix-targeted ubiquinone MitoQ10 acts as anti-oxidant at retarded electron transport or proton pumping within Complex I. | The international journal of biochemistry & cell biology 20090101 |
| Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1. | PloS one 20090101 |
| Retinal pigment epithelial cells secrete neurotrophic factors and synthesize dopamine: possible contribution to therapeutic effects of RPE cell transplantation in Parkinson's disease. | Journal of translational medicine 20090101 |
| Mitochondrial respiration is required for activation of ERK1/2 and caspase-3 in human eosinophils stimulated with hydrogen peroxide. | Journal of investigational allergology & clinical immunology 20090101 |
| Novel mitochondrial substrates of omi indicate a new regulatory role in neurodegenerative disorders. | PloS one 20090101 |
| Distribution characteristics of telithromycin, a novel ketolide antimicrobial agent applied for treatment of respiratory infection, in lung epithelial lining fluid and alveolar macrophages. | Drug metabolism and pharmacokinetics 20090101 |
| Stereotaxical infusion of rotenone: a reliable rodent model for Parkinson's disease. | PloS one 20090101 |
| [Grazing systems, rotenone and parasites control in crossbred calves: effect on live weight gain and on parasites burdens]. | Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria 20090101 |
| Effects of rotenone from derris crude extract on esterase enzyme mechanism in the beet armyworm, Spodoptera exiqua (Hubner). | Communications in agricultural and applied biological sciences 20090101 |
| The spinocerebellar ataxia 12 gene product and protein phosphatase 2A regulatory subunit Bbeta2 antagonizes neuronal survival by promoting mitochondrial fission. | The Journal of biological chemistry 20081226 |
| Glycolytic oscillations in isolated rabbit ventricular myocytes. | The Journal of biological chemistry 20081226 |
| Neuroprotective effects of near-infrared light in an in vivo model of mitochondrial optic neuropathy. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20081210 |
| Pretreatment with near-infrared light via light-emitting diode provides added benefit against rotenone- and MPP+-induced neurotoxicity. | Brain research 20081203 |
| Deguelin inhibits retinal neovascularization by down-regulation of HIF-1alpha in oxygen-induced retinopathy. | Journal of cellular and molecular medicine 20081201 |
| Comparison of glycolysis and oxidative phosphorylation as energy sources for mammalian sperm motility, using the combination of fluorescence imaging, laser tweezers, and real-time automated tracking and trapping. | Journal of cellular physiology 20081201 |
| Mechanism of the neuroprotective role of coenzyme Q10 with or without L-dopa in rotenone-induced parkinsonism. | Neuropharmacology 20081201 |
| Characterization of demethylation of methylmercury in cultured astrocytes. | Chemosphere 20081201 |
| Effect of magnesium ions on the activity of the cytosolic NADH/cytochrome c electron transport system. | The FEBS journal 20081201 |
| Unregulated mitochondrial GSK3beta activity results in NADH: ubiquinone oxidoreductase deficiency. | Neurotoxicity research 20081201 |
| Rotenone damages striatal organotypic slice culture. | Annals of the New York Academy of Sciences 20081201 |
| A novel derivative of the natural agent deguelin for cancer chemoprevention and therapy. | Cancer prevention research (Philadelphia, Pa.) 20081201 |
| Increased vulnerability to rotenone-induced neurotoxicity in ceruloplasmin-deficient mice. | Neuroscience letters 20081128 |
| Prostaglandin analogue misoprostol attenuates neurotoxin 1-methyl-4-phenylpyridinium-induced mitochondrial damage and cell death in differentiated PC12 cells. | Brain research bulletin 20081125 |
| Altered NAD(P)H production in neonatal rat islets resistant to H2O2. | Life sciences 20081121 |
| Interaction of mitochondrial respiratory inhibitors and excitotoxins potentiates cell death in hippocampal slice cultures. | Journal of neuroscience research 20081115 |
| Pitx3-transfected astrocytes secrete brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor and protect dopamine neurons in mesencephalon cultures. | Journal of neuroscience research 20081115 |
| Mitochondrial defects and dysfunction in calcium regulation in glaucomatous trabecular meshwork cells. | Investigative ophthalmology & visual science 20081101 |
| Complex I dysfunction redirects cellular and mitochondrial metabolism in Arabidopsis. | Plant physiology 20081101 |
| Mechanisms mediating the oxygen-induced vasoreactivity of the ductus arteriosus in the chicken embryo. | American journal of physiology. Regulatory, integrative and comparative physiology 20081101 |
| Mitochondria-derived reactive oxygen species mediate sympathoexcitation induced by angiotensin II in the rostral ventrolateral medulla. | Journal of hypertension 20081101 |
| Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts. | Annals of neurology 20081101 |
| [Cellular pathophysiology of Parkinson's disease]. | Rinsho shinkeigaku = Clinical neurology 20081101 |
| The role of external and matrix pH in mitochondrial reactive oxygen species generation. | The Journal of biological chemistry 20081024 |
| NADH oxidation drives respiratory Na+ transport in mitochondria from Yarrowia lipolytica. | Archives of microbiology 20081001 |
| Mitochondrial complex I inhibitor rotenone inhibits and redistributes vesicular monoamine transporter 2 via nitration in human dopaminergic SH-SY5Y cells. | Molecular pharmacology 20081001 |
| Channels for water efflux and influx involved in volume regulation of murine spermatozoa. | Reproduction (Cambridge, England) 20081001 |
| Role of mitochondria in modulation of spontaneous Ca2+ waves in freshly dispersed interstitial cells of Cajal from the rabbit urethra. | The Journal of physiology 20081001 |
| Phthalides from Pittosporum illicioides var. illicioides with inhibitory activity on superoxide generation and elastase release by neutrophils. | Journal of natural products 20081001 |
| Extranigral neurodegeneration in Parkinson's disease. | Annals of the New York Academy of Sciences 20081001 |
| Mitochondrial complex I inhibition is not required for dopaminergic neuron death induced by rotenone, MPP+, or paraquat. | Proceedings of the National Academy of Sciences of the United States of America 20080930 |
| Overexpression of Kir2.3 in PC12 cells resists rotenone-induced neurotoxicity associated with PKC signaling pathway. | Biochemical and biophysical research communications 20080919 |
| Rotenone inhibits delayed rectifier K+ current via a protein kinase A-dependent mechanism. | Neuroreport 20080917 |
| Oxygen flux as an indicator of physiological stress in fathead minnow (Pimephales promelas) embryos: a real-time biomonitoring system of water quality. | Environmental science & technology 20080915 |
| Rotenone-induced PC12 cell toxicity is caused by oxidative stress resulting from altered dopamine metabolism. | Toxicology in vitro : an international journal published in association with BIBRA 20080901 |
| Arterial baroreflex dysfunction fails to mimic Parkinson's disease in rats. | Journal of pharmacological sciences 20080901 |
| Opening of microglial K(ATP) channels inhibits rotenone-induced neuroinflammation. | Journal of cellular and molecular medicine 20080901 |
| Serine 129 phosphorylation of alpha-synuclein induces unfolded protein response-mediated cell death. | The Journal of biological chemistry 20080822 |
| Electrophysiology and pharmacology of striatal neuronal dysfunction induced by mitochondrial complex I inhibition. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080806 |
| Methionine sulfoxide reductase A protects dopaminergic cells from Parkinson's disease-related insults. | Free radical biology & medicine 20080801 |
| Rotenone-induced toxicity is mediated by Rho-GTPases in hippocampal neurons. | Toxicological sciences : an official journal of the Society of Toxicology 20080801 |
| First evidence for a crosstalk between mitochondrial and NADPH oxidase-derived reactive oxygen species in nitroglycerin-triggered vascular dysfunction. | Antioxidants & redox signaling 20080801 |
| Identification of regulatory pathways controlling gene expression of stress-responsive mitochondrial proteins in Arabidopsis. | Plant physiology 20080801 |
| Involvement of mitochondrial alteration and reactive oxygen species generation in Taiwan cobra cardiotoxin-induced apoptotic death of human neuroblastoma SK-N-SH cells. | Toxicon : official journal of the International Society on Toxinology 20080801 |
| Modulation of SIRT1 expression in different neurodegenerative models and human pathologies. | Neuroscience 20080717 |
| Mitochondrial respiratory complex I regulates neutrophil activation and severity of lung injury. | American journal of respiratory and critical care medicine 20080715 |
| Mitochondrial localization of alpha-synuclein protein in alpha-synuclein overexpressing cells. | Neuroscience letters 20080711 |
| Decylubiquinol impedes mitochondrial respiratory chain complex I activity. | Molecular and cellular biochemistry 20080701 |
| Protective effect of the green tea component, L-theanine on environmental toxins-induced neuronal cell death. | Neurotoxicology 20080701 |
| GSK3beta and endoplasmic reticulum stress mediate rotenone-induced death of SK-N-MC neuroblastoma cells. | Biochemical pharmacology 20080701 |
| Deguelin inhibits human hepatocellular carcinoma by antiangiogenesis and apoptosis. | Oncology reports 20080701 |
| Essential roles of caspases and their upstream regulators in rotenone-induced apoptosis. | Biochemical and biophysical research communications 20080620 |
| Neuroprotective effects of memantine in a mouse model of retinal degeneration induced by rotenone. | Brain research 20080618 |
| Aroyl hydrazones of 2-phenylindole-3-carbaldehydes as novel antimitotic agents. | Bioorganic & medicinal chemistry 20080615 |
| Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). | Journal of medicinal chemistry 20080612 |
| Interactions between PBEF and oxidative stress proteins--a potential new mechanism underlying PBEF in the pathogenesis of acute lung injury. | FEBS letters 20080611 |
| Near-infrared light via light-emitting diode treatment is therapeutic against rotenone- and 1-methyl-4-phenylpyridinium ion-induced neurotoxicity. | Neuroscience 20080602 |
| Mechanisms of DJ-1 neuroprotection in a cellular model of Parkinson's disease. | Journal of neurochemistry 20080601 |
| Induction of HIF-2alpha is dependent on mitochondrial O2 consumption in an O2-sensitive adrenomedullary chromaffin cell line. | American journal of physiology. Cell physiology 20080601 |
| L-Proline uptake in Crithidia deanei is influenced by its endosymbiont bacterium. | FEMS microbiology letters 20080601 |
| STIM1 regulates acidic Ca2+ store refilling by interaction with SERCA3 in human platelets. | Biochemical pharmacology 20080601 |
| Isoflavones and rotenoids from the leaves of Millettia brandisiana. | Chemical & pharmaceutical bulletin 20080601 |
| Enhancement radiosensitization of breast cancer cells by deguelin. | Cancer biotherapy & radiopharmaceuticals 20080601 |
| Synthesis and biological evaluation of pyridazinone analogues as potential cardiac positron emission tomography tracers. | Journal of medicinal chemistry 20080522 |
| Nmnat delays axonal degeneration caused by mitochondrial and oxidative stress. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080507 |
| Dopamine selectively sensitizes dopaminergic neurons to rotenone-induced apoptosis. | Neurochemical research 20080501 |
| Degradation of caspase-activated DNase by the ubiquitin-proteasome system. | Biochimica et biophysica acta 20080501 |
| Hymenolepis diminuta: mitochondrial transhydrogenase as an additional site for anaerobic phosphorylation. | Experimental parasitology 20080501 |
| Role and regulation of ferritin H in rotenone-mediated mitochondrial oxidative stress. | Free radical biology & medicine 20080501 |
| Nitric oxide degradation by potato tuber mitochondria: evidence for the involvement of external NAD(P)H dehydrogenases. | Biochimica et biophysica acta 20080501 |
| Oxidative insults induce DJ-1 upregulation and redistribution: implications for neuroprotection. | Neurotoxicology 20080501 |
| Inhibition of carrier-mediated uptake of epirubicin reduces cytotoxicity in primary culture of rat hepatocytes. | Journal of applied toxicology : JAT 20080401 |
| Hypoxanthine uptake and release by equilibrative nucleoside transporter 2 (ENT2) of rat microvascular endothelial cells. | Microvascular research 20080401 |
| TNF-alpha/cycloheximide-induced apoptosis in intestinal epithelial cells requires Rac1-regulated reactive oxygen species. | American journal of physiology. Gastrointestinal and liver physiology 20080401 |
| Mitochondrial complex I defect induces ROS release and degeneration in trabecular meshwork cells of POAG patients: protection by antioxidants. | Investigative ophthalmology & visual science 20080401 |
| Interplay between bax, reactive oxygen species production, and cardiolipin oxidation during apoptosis. | Biochemical and biophysical research communications 20080328 |
| Behavioral alterations in rotenone model of Parkinson's disease: attenuation by co-treatment of centrophenoxine. | Brain research 20080327 |
| Mechanistic investigations of low dose exposures to the genotoxic compounds bisphenol-A and rotenone. | Mutation research 20080312 |
| Effects of the extract of Anemopaegma mirandum (Catuaba) on Rotenone-induced apoptosis in human neuroblastomas SH-SY5Y cells. | Brain research 20080310 |
| D2/D3 receptor agonist ropinirole protects dopaminergic cell line against rotenone-induced apoptosis through inhibition of caspase- and JNK-dependent pathways. | FEBS letters 20080305 |
| Sequential and concerted gene expression changes in a chronic in vitro model of parkinsonism. | Neuroscience 20080303 |
| ATP depletion inhibits Ca2+ release, influx and extrusion in pancreatic acinar cells but not pathological Ca2+ responses induced by bile. | Pflugers Archiv : European journal of physiology 20080301 |
| Protocatechuic acid inhibits apoptosis by mitochondrial dysfunction in rotenone-induced PC12 cells. | Toxicology in vitro : an international journal published in association with BIBRA 20080301 |
| Melatonin reduces the neuronal loss, downregulation of dopamine transporter, and upregulation of D2 receptor in rotenone-induced parkinsonian rats. | Journal of pineal research 20080301 |
| Investigating convergent actions of genes linked to familial Parkinson's disease. | Neuro-degenerative diseases 20080301 |
| Shear fluid-induced Ca2+ release and the role of mitochondria in rat cardiac myocytes. | Annals of the New York Academy of Sciences 20080301 |
| Fibroblasts from naked mole-rats are resistant to multiple forms of cell injury, but sensitive to peroxide, ultraviolet light, and endoplasmic reticulum stress. | The journals of gerontology. Series A, Biological sciences and medical sciences 20080301 |
| The role of dopamine transporter in selective toxicity of manganese and rotenone. | Toxicology 20080227 |
| Dopaminergic neurons are preferentially sensitive to long-term rotenone toxicity in primary cell culture. | Toxicology in vitro : an international journal published in association with BIBRA 20080201 |
| Antiangiogenic effect of deguelin on choroidal neovascularization. | The Journal of pharmacology and experimental therapeutics 20080201 |
| Ischemic defects in the electron transport chain increase the production of reactive oxygen species from isolated rat heart mitochondria. | American journal of physiology. Cell physiology 20080201 |
| Uncoupling protein-2 accumulates rapidly in the inner mitochondrial membrane during mitochondrial reactive oxygen stress in macrophages. | Biochimica et biophysica acta 20080201 |
| Protection against oxidant-induced apoptosis by exogenous glutathione in Leber hereditary optic neuropathy cybrids. | Investigative ophthalmology & visual science 20080201 |
| Preparative isolation and purification of three rotenoids and one isoflavone from the seeds of Millettia pachycarpa Benth by high-speed counter-current chromatography. | Journal of chromatography. A 20080118 |
| ATP depletion inhibits the endocytosis of ClC-2. | Journal of cellular physiology 20080101 |
| Rotenoid derivatives and other constituents of the twigs of Millettia duchesnei. | Phytochemistry 20080101 |
| Identification of novel antiangiogenic anticancer activities of deguelin targeting hypoxia-inducible factor-1 alpha. | International journal of cancer 20080101 |
| Alterations of striatal glutamate transmission in rotenone-treated mice: MRI/MRS in vivo studies. | Experimental neurology 20080101 |
| The exploration of rotenone as a toxin for inducing Parkinson's disease in rats, for application in BBB transport and PK-PD experiments. | Journal of pharmacological and toxicological methods 20080101 |
| Deguelin represses both the expression of nucleophosmin and some nucleoporins: Nup88 and Nup214 in Jurkat cells. | Biological & pharmaceutical bulletin 20080101 |
| Protection by the NDI1 gene against neurodegeneration in a rotenone rat model of Parkinson's disease. | PloS one 20080101 |
| Oxidative stress caused by blocking of mitochondrial complex I H(+) pumping as a link in aging/disease vicious cycle. | The international journal of biochemistry & cell biology 20080101 |
| The influence of visible light exposure on cultured RGC-5 cells. | Molecular vision 20080101 |
| Studies on cellular resilience and adaptation following acute and repetitive exposure to ozone in cultured human epithelial (HeLa) cells. | Redox report : communications in free radical research 20080101 |
| Isoflavonoid glycosides and rotenoids from Pongamia pinnata leaves. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20080101 |
| Malate metabolism in Hoya carnosa mitochondria and its role in photosynthesis during CAM phase III. | Journal of experimental botany 20080101 |
| Altered threshold of the mitochondrial permeability transition pore in Ullrich congenital muscular dystrophy. | Biochimica et biophysica acta 20080101 |
| Transgenic mice expressing cyan fluorescent protein as a reporter strain to detect the effects of rotenone toxicity on retinal ganglion cells. | Journal of toxicology and environmental health. Part A 20080101 |
| CD133 is a marker of bioenergetic stress in human glioma. | PloS one 20080101 |
| Pesticide/environmental exposures and Parkinson's disease in East Texas. | Journal of agromedicine 20080101 |
| Mitochondrial production of reactive oxygen species: role of complex I and quinone analogues. | BioFactors (Oxford, England) 20080101 |
| NADPH-dependent coenzyme Q reductase is the main enzyme responsible for the reduction of non-mitochondrial CoQ in cells. | BioFactors (Oxford, England) 20080101 |
| Chronic, low-dose rotenone reproduces Lewy neurites found in early stages of Parkinson's disease, reduces mitochondrial movement and slowly kills differentiated SH-SY5Y neural cells. | Molecular neurodegeneration 20080101 |
| [Two molecular motility systems of the frog olfactory cilia]. | Biofizika 20080101 |
| Flow cytometric quantification of glucose-stimulated beta-cell metabolic flux can reveal impaired islet functional potency. | Cell transplantation 20080101 |
| Reversible dissociation of flavin mononucleotide from the mammalian membrane-bound NADH: ubiquinone oxidoreductase (complex I). | FEBS letters 20071222 |
| Implication of AMP-activated protein kinase and Akt-regulated survivin in lung cancer chemopreventive activities of deguelin. | Cancer research 20071215 |
| Iptakalim alleviates rotenone-induced degeneration of dopaminergic neurons through inhibiting microglia-mediated neuroinflammation. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20071201 |
| Differential effects of classical and atypical antipsychotic drugs on rotenone-induced neurotoxicity in PC12 cells. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20071201 |
| HIF-1 regulates hypoxia- and insulin-induced expression of apelin in adipocytes. | American journal of physiology. Endocrinology and metabolism 20071201 |
| Chondroitin sulfate protects SH-SY5Y cells from oxidative stress by inducing heme oxygenase-1 via phosphatidylinositol 3-kinase/Akt. | The Journal of pharmacology and experimental therapeutics 20071201 |
| Phytanic acid impairs mitochondrial respiration through protonophoric action. | Cellular and molecular life sciences : CMLS 20071201 |
| Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species. | Journal of cell science 20071201 |
| Effect of intermittent normobaric hypoxia on kinetic properties of mitochondrial enzymes. | Bulletin of experimental biology and medicine 20071201 |
| Integrating glutathione metabolism and mitochondrial dysfunction with implications for Parkinson's disease: a dynamic model. | Neuroscience 20071123 |
| Rotenone enhances N-methyl-D-aspartate currents by activating a tyrosine kinase in rat dopamine neurons. | Neuroreport 20071119 |
| Direct evidence for the action of phosphatidylinositol (3,4,5)-trisphosphate-mediated signal transduction in the 2-cell mouse embryo. | Biology of reproduction 20071101 |
| Reactive oxygen species (ROS) mediate the effects of leucine on translation regulation and type I collagen production in hepatic stellate cells. | Biochimica et biophysica acta 20071101 |
| Mitochondrial complex I inhibitor rotenone-elicited dopamine redistribution from vesicles to cytosol in human dopaminergic SH-SY5Y cells. | The Journal of pharmacology and experimental therapeutics 20071101 |
| Chronic inhalation of rotenone or paraquat does not induce Parkinson's disease symptoms in mice or rats. | Experimental neurology 20071101 |
| Epigallocatechin gallate (EGCG) potentiates the cytotoxicity of rotenone in neuroblastoma SH-SY5Y cells. | Brain research 20071024 |
| Involvement of Candida albicans pyruvate dehydrogenase complex protein X (Pdx1) in filamentation. | Fungal genetics and biology : FG & B 20071001 |
| Rotenone selectively kills serotonergic neurons through a microtubule-dependent mechanism. | Journal of neurochemistry 20071001 |
| Zaprinast inhibits hydrogen peroxide-induced lysosomal destabilization and cell death in astrocytes. | European journal of pharmacology 20071001 |
| Mitochondrial DNA deletions induce the adenosine monophosphate-activated protein kinase energy stress pathway and result in decreased secretion of some proteins. | Aging cell 20071001 |
| Memantine reduces neuronal dysfunctions triggered by in vitro ischemia and 3-nitropropionic acid. | Experimental neurology 20071001 |
| Bioenergetic and oxidative effects of free 3-nitrotyrosine in culture: selective vulnerability of dopaminergic neurons and increased sensitivity of non-dopaminergic neurons to dopamine oxidation. | Journal of neurochemistry 20071001 |
| Redox-dependent change of nucleotide affinity to the active site of the mammalian complex I. | Biochemistry 20070925 |
| Synthesis and biological evaluation of the mitochondrial complex 1 inhibitor 2-[4-(4-fluorobutyl)benzylsulfanyl]-3-methylchromene-4-one as a potential cardiac positron emission tomography tracer. | Journal of medicinal chemistry 20070906 |
| Role of AMP-activated protein kinase in exercise capacity, whole body glucose homeostasis, and glucose transport in skeletal muscle -insight from analysis of a transgenic mouse model-. | Diabetes research and clinical practice 20070901 |
| Rapid down-regulation of Ret following exposure of dopaminergic neurons to neurotoxins. | Journal of neurochemistry 20070901 |
| Aldosterone induces epithelial-mesenchymal transition via ROS of mitochondrial origin. | American journal of physiology. Renal physiology 20070901 |
| Mitochondrial and cytosolic thiol redox state are not detectably altered in isolated human NADH:ubiquinone oxidoreductase deficiency. | Biochimica et biophysica acta 20070901 |
| Modulation of TASK-like background potassium channels in rat arterial chemoreceptor cells by intracellular ATP and other nucleotides. | The Journal of physiology 20070901 |
| Rotenone inhibits mammalian cell proliferation by inhibiting microtubule assembly through tubulin binding. | The FEBS journal 20070901 |
| Comparison of the cytotoxicity of the nitroaromatic drug flutamide to its cyano analogue in the hepatocyte cell line TAMH: evidence for complex I inhibition and mitochondrial dysfunction using toxicogenomic screening. | Chemical research in toxicology 20070901 |
| Endoplasmic reticulum is a key organella in bradykinin-triggered ATP release from cultured smooth muscle cells. | Journal of pharmacological sciences 20070901 |
| Photodegradation of rotenone in soils under environmental conditions. | Journal of agricultural and food chemistry 20070822 |
| Mechanism of cell death caused by complex I defects in a rat dopaminergic cell line. | The Journal of biological chemistry 20070817 |
| Drosophila overexpressing parkin R275W mutant exhibits dopaminergic neuron degeneration and mitochondrial abnormalities. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20070808 |
| Target identification of drug induced mitochondrial toxicity using immunocapture based OXPHOS activity assays. | Toxicology in vitro : an international journal published in association with BIBRA 20070801 |
| Deguelin inhibits expression of IkappaBalpha protein and induces apoptosis of B-CLL cells in vitro. | Leukemia 20070801 |
| Dual role of mitochondrial reactive oxygen species in hypoxia signaling: activation of nuclear factor-{kappa}B via c-SRC and oxidant-dependent cell death. | Cancer research 20070801 |
| Unique responses to mitochondrial complex I inhibition in tuberoinfundibular dopamine neurons may impart resistance to toxic insult. | Neuroscience 20070713 |
| Spare respiratory capacity rather than oxidative stress regulates glutamate excitotoxicity after partial respiratory inhibition of mitochondrial complex I with rotenone. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20070704 |
| Regulation of transient receptor potential melastatin 7 (TRPM7) currents by mitochondria. | Molecules and cells 20070630 |
| 'Rejuvenation' protects neurons in mouse models of Parkinson's disease. | Nature 20070628 |
| Rotenone potentiates NMDA currents in substantia nigra dopamine neurons. | Neuroscience letters 20070627 |
| Astrocytes protect MN9D neuronal cells against rotenone-induced oxidative stress by a glutathione-dependent mechanism. | Sheng li xue bao : [Acta physiologica Sinica] 20070625 |
| Structural basis for depletion of heat shock protein 90 client proteins by deguelin. | Journal of the National Cancer Institute 20070620 |
| Rotenone-induced neurotoxicity of THP-1 cells requires production of reactive oxygen species and activation of phosphatidylinositol 3-kinase. | Brain research 20070611 |
| Mitochondrial OXPHOS functions in R1H rhabdomyosarcoma and skeletal muscles of the rat. | Neurochemical research 20070601 |
| Neurodegeneration of mouse nigrostriatal dopaminergic system induced by repeated oral administration of rotenone is prevented by 4-phenylbutyrate, a chemical chaperone. | Journal of neurochemistry 20070601 |
| Complex I binding by a virally encoded RNA regulates mitochondria-induced cell death. | Science (New York, N.Y.) 20070601 |
| [Rotenoids from Derris trifoliata]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070601 |
| The parkinsonian neurotoxin rotenone activates calpain and caspase-3 leading to motoneuron degeneration in spinal cord of Lewis rats. | Neuroscience 20070511 |
| [Proteolytic stress induced by environmental toxins in dopaminergic neurons: an experimental study]. | Zhonghua yi xue za zhi 20070508 |
| Effects of temperature on pacemaker potentials in the mouse small intestine. | Pflugers Archiv : European journal of physiology 20070501 |
| Exercise training decreases rat heart mitochondria free radical generation but does not prevent Ca2+-induced dysfunction. | Journal of applied physiology (Bethesda, Md. : 1985) 20070501 |
| Activation of c-Jun N-terminal protein kinase is a common mechanism underlying paraquat- and rotenone-induced dopaminergic cell apoptosis. | Toxicological sciences : an official journal of the Society of Toxicology 20070501 |
| Endogenous production of reactive oxygen species is required for stimulation of human articular chondrocyte matrix metalloproteinase production by fibronectin fragments. | Free radical biology & medicine 20070501 |
| Effect of the inhibitory neurotransmitter glycine on slow destructive processes in brain cortex slices under anoxic conditions. | Biochemistry. Biokhimiia 20070501 |
| Inhibition of cyclin-dependent kinases is neuroprotective in 1-methyl-4-phenylpyridinium-induced apoptosis in neurons. | Neuroscience 20070425 |
| ROS generation in endothelial hypoxia and reoxygenation stimulates MAP kinase signaling and kinase-dependent neutrophil recruitment. | Free radical biology & medicine 20070415 |
| Stereoselective syntheses of the 2-Isopropenyl-2,3-dihydrobenzofuran nucleus: potential chiral building blocks for the syntheses of tremetone, hydroxytremetone, and rotenone. | The Journal of organic chemistry 20070413 |
| Melatonin protects against rotenone-induced oxidative stress in a hemiparkinsonian rat model. | Journal of pineal research 20070401 |
| Mitochondrial delivery is essential for synaptic potentiation. | The Biological bulletin 20070401 |
| Behavioural and neural deficits induced by rotenone in the pond snail Lymnaea stagnalis. A possible model for Parkinson's disease in an invertebrate. | The European journal of neuroscience 20070401 |
| Anti-cancer effects of deguelin on human leukemia K562 and K562/ADM cells In Vitro. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20070401 |
| Interleukin-1beta mediates sleep alteration in rats with rotenone-induced parkinsonism. | Sleep 20070401 |
| Lamotrigine inhibition of rotenone- or 1-methyl-4-phenylpyridinium-induced mitochondrial damage and cell death. | Brain research bulletin 20070330 |
| A genomic screen for activators of the antioxidant response element. | Proceedings of the National Academy of Sciences of the United States of America 20070320 |
| AKT and CDK5/p35 mediate brain-derived neurotrophic factor induction of DARPP-32 in medium size spiny neurons in vitro. | The Journal of biological chemistry 20070309 |
| Rotenone and MPP+ preferentially redistribute apoptosis-inducing factor in apoptotic dopamine neurons. | Neuroreport 20070305 |
| A rotenone-sensitive site and H2O2 are key components of hypoxia-sensing in neonatal rat adrenomedullary chromaffin cells. | Neuroscience 20070302 |
| Neuroprotective effects of ginsenoside-Rg1 in primary nigral neurons against rotenone toxicity. | Neuropharmacology 20070301 |
| Pharmacological and physiological stimuli do not promote Ca(2+)-sensitive K+ channel activity in isolated heart mitochondria. | Cardiovascular research 20070301 |
| RNAi knockdown of caspase-activated DNase inhibits rotenone-induced DNA fragmentation in HeLa cells. | Neurochemistry international 20070301 |
| Mechanism of toxicity of pesticides acting at complex I: relevance to environmental etiologies of Parkinson's disease. | Journal of neurochemistry 20070301 |
| Alpha-synuclein and tyrosine hydroxylase expression in acute rotenone toxicity. | International journal of molecular medicine 20070301 |
| [Effect of deguelin on proliferation and apoptosis of lymphoma Daudi cells and its mechanism]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20070301 |
| Chronic rotenone treatment induces behavioral effects but no pathological signs of parkinsonism in mice. | Journal of neuroscience research 20070215 |
| Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells. | Cancer chemotherapy and pharmacology 20070201 |
| The Akt inhibitor deguelin, is an angiopreventive agent also acting on the NF-kappaB pathway. | Carcinogenesis 20070201 |
| Bidirectional Ca2+ coupling of mitochondria with the endoplasmic reticulum and regulation of multimodal Ca2+ entries in rat brown adipocytes. | American journal of physiology. Cell physiology 20070201 |
| Mitochondria mass is low in mouse substantia nigra dopamine neurons: implications for Parkinson's disease. | Experimental neurology 20070201 |
| ATP depletion does not account for apoptosis induced by inhibition of mitochondrial electron transport chain in human dopaminergic cells. | Neuropharmacology 20070201 |
| Standardized Hypericum perforatum reduces oxidative stress and increases gene expression of antioxidant enzymes on rotenone-exposed rats. | Neuropharmacology 20070201 |
| RNA interference-mediated knockdown of alpha-synuclein protects human dopaminergic neuroblastoma cells from MPP(+) toxicity and reduces dopamine transport. | Journal of neuroscience research 20070201 |
| Skin-derived fibroblasts from long-lived species are resistant to some, but not all, lethal stresses and to the mitochondrial inhibitor rotenone. | Aging cell 20070201 |
| Rotenoids and flavonoids with anti-invasion of HT1080, anti-proliferation of U937, and differentiation-inducing activity in HL-60 from Erycibe expansa. | Bioorganic & medicinal chemistry 20070201 |
| [Effect of deguelin on expression of nup98 in K562 cells]. | Zhongguo shi yan xue ye xue za zhi 20070201 |
| [Deguelin regulates cell cycle and nuclear pore complex protein Nup98 and Nup88 in U937 cells in vitro]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20070201 |
| Moderate dependence of ROS formation on DeltaPsim in isolated brain mitochondria supported by NADH-linked substrates. | Neurochemical research 20070101 |
| Divergent mechanisms of paraquat, MPP+, and rotenone toxicity: oxidation of thioredoxin and caspase-3 activation. | Toxicological sciences : an official journal of the Society of Toxicology 20070101 |
| Down-regulation of inhibitor of apoptosis proteins by deguelin selectively induces apoptosis in breast cancer cells. | Molecular pharmacology 20070101 |
| Mitochondrial damage modulates alternative splicing in neuronal cells: implications for neurodegeneration. | Journal of neurochemistry 20070101 |
| Mitochondrial toxins and neurodegenerative diseases. | Frontiers in bioscience : a journal and virtual library 20070101 |
| Pesticides and impairment of mitochondrial function in relation with the parkinsonian syndrome. | Frontiers in bioscience : a journal and virtual library 20070101 |
| Effect of tributyltin (TBT) on ATP levels in human natural killer (NK) cells: relationship to TBT-induced decreases in NK function. | Journal of applied toxicology : JAT 20070101 |
| Quantification of basal and stimulated ROS levels as predictors of islet potency and function. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070101 |
| CHOP (C/EBP homologous protein) and ASNS (asparagine synthetase) induction in cybrid cells harboring MELAS and NARP mitochondrial DNA mutations. | Mitochondrion 20070101 |
| Evidence of ROS generation by mitochondria in cells with impaired electron transport chain and mitochondrial DNA damage. | Mitochondrion 20070101 |
| [Hepatocyte mitochondrion respiratory chain in rats with experimental toxic hepatitis]. | Tsitologiia 20070101 |
| Is Parkinson's disease an autoimmune disorder of endogenous vasoactive neuropeptides? | Medical hypotheses 20070101 |
| The responses of HT22 cells to the blockade of mitochondrial complexes and potential protective effect of selenium supplementation. | International journal of biological sciences 20070101 |
| Identification of novel proteins affected by rotenone in mitochondria of dopaminergic cells. | BMC neuroscience 20070101 |
| Evaluation of the impact on entomocoenosis of active agents allowed in organic olive farming against Bactrocera oleae (Gmelin, 1790). | Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20070101 |
| [Wheat root cells functioning under inhibition of I and II complexes of mitochondrial respiratory chain]. | Tsitologiia 20070101 |
| [The experimental models of Parkinson's disease in animals]. | Uspekhi fiziologicheskikh nauk 20070101 |
| Isolation and functional analysis of mitochondria from the nematode Caenorhabditis elegans. | Methods in molecular biology (Clifton, N.J.) 20070101 |
| Mitochondrial ROS-PKCepsilon signaling axis is uniquely involved in hypoxic increase in [Ca2+]i in pulmonary artery smooth muscle cells. | Biochemical and biophysical research communications 20061222 |
| Mitochondrial production of reactive oxygen species mediate dicumarol-induced cytotoxicity in cancer cells. | The Journal of biological chemistry 20061208 |
| Pyruvate and oxaloacetate limit zinc-induced oxidative HT-22 neuronal cell injury. | Neurotoxicology 20061201 |
| NR2B-containing NMDA receptors promote the neurotoxic effects of 3-nitropropionic acid but not of rotenone in the striatum. | Experimental neurology 20061201 |
| Significant increase of glycolytic flux in Torulopsis glabrata by inhibition of oxidative phosphorylation. | FEMS yeast research 20061201 |
| Microtubule: a common target for parkin and Parkinson's disease toxins. | The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 20061201 |
| Transient and partial mitochondrial inhibition for the treatment of postresuscitation injury: getting it just right. | Critical care medicine 20061201 |
| Accumulation of lipophilic dications by mitochondria and cells. | The Biochemical journal 20061115 |
| Carnosol, a component of rosemary (Rosmarinus officinalis L.) protects nigral dopaminergic neuronal cells. | Neuroreport 20061106 |
| D-beta-hydroxybutyrate protects dopaminergic SH-SY5Y cells in a rotenone model of Parkinson's disease. | Journal of neuroscience research 20061101 |
| Partial mitochondrial complex I inhibition induces oxidative damage and perturbs glutamate transport in primary retinal cultures. Relevance to Leber Hereditary Optic Neuropathy (LHON). | Neurobiology of disease 20061101 |
| Correlated resistance to glucose deprivation and cytotoxic agents in fibroblast cell lines from long-lived pituitary dwarf mice. | Mechanisms of ageing and development 20061101 |
| Structures of new flavonoids, erycibenins D, E, and F, and NO production inhibitors from Erycibe expansa originating in Thailand. | Chemical & pharmaceutical bulletin 20061101 |
| [Overexpression of alpha-synuclein in SH-SY5Y cells partially protected against oxidative stress induced by rotenone]. | Sheng li xue bao : [Acta physiologica Sinica] 20061025 |
| Deguelin, an Akt inhibitor, suppresses IkappaBalpha kinase activation leading to suppression of NF-kappaB-regulated gene expression, potentiation of apoptosis, and inhibition of cellular invasion. | Journal of immunology (Baltimore, Md. : 1950) 20061015 |
| Mitochondrial activity is modulated by TNFalpha and IL-1beta in normal human chondrocyte cells. | Osteoarthritis and cartilage 20061001 |
| Iptakalim modulates ATP-sensitive K(+) channels in dopamine neurons from rat substantia nigra pars compacta. | The Journal of pharmacology and experimental therapeutics 20061001 |
| Geographic isolates of atypical Parkinsonism and tauopathy in the tropics: possible synergy of neurotoxins. | Movement disorders : official journal of the Movement Disorder Society 20061001 |
| Differential effect of nerve growth factor on dopaminergic neurotoxin-induced apoptosis. | Journal of neurochemistry 20061001 |
| Neurotrophic factors stabilize microtubules and protect against rotenone toxicity on dopaminergic neurons. | The Journal of biological chemistry 20060929 |
| RTP801 is elevated in Parkinson brain substantia nigral neurons and mediates death in cellular models of Parkinson's disease by a mechanism involving mammalian target of rapamycin inactivation. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060927 |
| Rotenone induces cell death in primary dopaminergic culture by increasing ROS production and inhibiting mitochondrial respiration. | Neurochemistry international 20060901 |
| Potentiating effect of the ATP-sensitive potassium channel blocker glibenclamide on complex I inhibitor neurotoxicity in vitro and in vivo. | Neurotoxicology 20060901 |
| Extraction of rotenone from Derris elliptica and Derris malaccensis by pressurized liquid extraction compared with maceration. | Journal of chromatography. A 20060901 |
| Neurodegeneration produced by rotenone in the mouse retina: a potential model to investigate environmental pesticide contributions to neurodegenerative diseases. | Journal of toxicology and environmental health. Part A 20060901 |
| alpha-Synuclein redistributed and aggregated in rotenone-induced Parkinson's disease rats. | Neuroscience bulletin 20060901 |
| Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons. | The EMBO journal 20060823 |
| Copper-induced stimulation of extracellular signal-regulated kinase in trout hepatocytes: the role of reactive oxygen species, Ca2+, and cell energetics and the impact of extracellular signal-regulated kinase signaling on apoptosis and necrosis. | Toxicological sciences : an official journal of the Society of Toxicology 20060801 |
| Mitochondrial damage due to SOD1 deficiency in SH-SY5Y neuroblastoma cells: a rationale for the redundancy of SOD1. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060801 |
| Mitochondrial disease activates transcripts of the unfolded protein response and cell cycle and inhibits vesicular secretion and oligodendrocyte-specific transcripts. | Mitochondrion 20060801 |
| Albumin-bound fatty acids induce mitochondrial oxidant stress and impair antioxidant responses in proximal tubular cells. | Kidney international 20060801 |
| Cytotoxic mechanisms of Zn2+ and Cd2+ involve Na+/H+ exchanger (NHE) activation by ROS. | Aquatic toxicology (Amsterdam, Netherlands) 20060720 |
| Electron transport complex I is required for CD8+ T cell function. | Journal of immunology (Baltimore, Md. : 1950) 20060715 |
| p44/42 MAP kinase and c-Jun N-terminal kinase contribute to the up-regulation of caspase-3 in manganese-induced apoptosis in PC12 cells. | Brain research 20060712 |
| Chromatographic analysis of dopamine metabolism in a Parkinsonian model. | Journal of chromatography. A 20060707 |
| L-deprenyl protects against rotenone-induced, oxidative stress-mediated dopaminergic neurodegeneration in rats. | Neurochemistry international 20060701 |
| Proteomic identification of a stress protein, mortalin/mthsp70/GRP75: relevance to Parkinson disease. | Molecular & cellular proteomics : MCP 20060701 |
| Enhanced sensitivity of DJ-1-deficient dopaminergic neurons to energy metabolism impairment: role of Na+/K+ ATPase. | Neurobiology of disease 20060701 |
| Benzothiadiazole inhibits mitochondrial NADH:ubiquinone oxidoreductase in tobacco. | Journal of plant physiology 20060701 |
| Mitochondrial reactive oxygen species are required for hypothalamic glucose sensing. | Diabetes 20060701 |
| Monocyte-mediated rotenone neurotoxicity towards human neuroblastoma SH-SY5Y: role of mitogen-activated protein kinases. | Biological & pharmaceutical bulletin 20060701 |
| Stability of membrane potential in heart mitochondria: single mitochondrion imaging. | Biochemical and biophysical research communications 20060616 |
| Cytoprotection by lithium and valproate varies between cell types and cellular stresses. | European journal of pharmacology 20060606 |
| Increased sensitivity to MPTP in human alpha-synuclein A30P transgenic mice. | Neurobiology of aging 20060601 |
| Antioxidant and 15-lipoxygenase inhibitory activity of rotenoids, isoflavones and phenolic glycosides from Sarcolobus globosus. | Fitoterapia 20060601 |
| Rats with unilateral median forebrain bundle, but not striatal or nigral, lesions by the neurotoxins MPP+ or rotenone display differential sensitivity to amphetamine and apomorphine. | Pharmacology, biochemistry, and behavior 20060601 |
| In vivo complementation of complex I by the yeast Ndi1 enzyme. Possible application for treatment of Parkinson disease. | The Journal of biological chemistry 20060519 |
| Proteasomal inhibition hypersensitizes differentiated neuroblastoma cells to oxidative damage. | Neuroscience letters 20060515 |
| Parkin protects against mitochondrial toxins and beta-amyloid accumulation in skeletal muscle cells. | The Journal of biological chemistry 20060505 |
| Mitochondrial reactive oxygen species contribute to high NaCl-induced activation of the transcription factor TonEBP/OREBP. | American journal of physiology. Renal physiology 20060501 |
| Intersecting pathways to neurodegeneration in Parkinson's disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system. | Neurobiology of disease 20060501 |
| Enhanced sensitivity of dopaminergic neurons to rotenone-induced toxicity with aging. | Parkinsonism & related disorders 20060501 |
| Definitive evidence for the nonmitochondrial production of superoxide anion by human spermatozoa. | The Journal of clinical endocrinology and metabolism 20060501 |
| Susceptibility to rotenone is increased in neurons from parkin null mice and is reduced by minocycline. | Journal of neurochemistry 20060501 |
| Neurodegeneration induced by complex I inhibition in a cellular model of familial amyotrophic lateral sclerosis. | Brain research bulletin 20060428 |
| Basic fibroblast growth factor protects against rotenone-induced dopaminergic cell death through activation of extracellular signal-regulated kinases 1/2 and phosphatidylinositol-3 kinase pathways. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060426 |
| Activation of group III metabotropic glutamate receptors attenuates rotenone toxicity on dopaminergic neurons through a microtubule-dependent mechanism. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060419 |
| Metallothionein isoform 2A expression is inducible and protects against ROS-mediated cell death in rotenone-treated HeLa cells. | The Biochemical journal 20060415 |
| Tamoxifen and estradiol interact with the flavin mononucleotide site of complex I leading to mitochondrial failure. | The Journal of biological chemistry 20060414 |
| Early induction of calpains in rotenone-mediated neuronal apoptosis. | Neuroscience letters 20060401 |
| Deguelin inhibits expression of IkappaBalpha protein in Raji and U937 cells. | Acta pharmacologica Sinica 20060401 |
| Not only insulin stimulates mitochondriogenesis in muscle cells, but mitochondria are also essential for insulin-mediated myogenesis. | Cell proliferation 20060401 |
| Electron transport pathways for the oxidation of endogenous substrate(s) in Acidithiobacillus ferrooxidans. | Canadian journal of microbiology 20060401 |
| Inhibition of specific electron transport pathways leads to oxidative stress and decreased Candida albicans proliferation. | Journal of bioenergetics and biomembranes 20060401 |
| Synergism of rotenone by piperonyl butoxide in Haemonchus contortus and Trichostrongylus colubriformis in vitro: potential for drug-synergism through inhibition of nematode oxidative detoxification pathways. | Veterinary parasitology 20060331 |
| Rotenone-like action of the branched-chain phytanic acid induces oxidative stress in mitochondria. | The Journal of biological chemistry 20060317 |
| Depletion of cardiolipin and cytochrome c during ischemia increases hydrogen peroxide production from the electron transport chain. | Free radical biology & medicine 20060315 |
| Tetrahydrobiopterin causes mitochondrial dysfunction in dopaminergic cells: implications for Parkinson's disease. | Neurochemistry international 20060301 |
| Mitochondrial Ca2+ flux is a critical determinant of the Ca2+ dependence of mast cell degranulation. | Journal of leukocyte biology 20060301 |
| Mitochondrial electron transport in models of neuropathic and inflammatory pain. | Pain 20060301 |
| Comparison of larvicidal, adulticidal and acaricidal activity of two geometrical butylidenephthalide isomers. | Biological & pharmaceutical bulletin 20060301 |
| The regulation of rotenone-induced inflammatory factor production by ATP-sensitive potassium channel expressed in BV-2 cells. | Neuroscience letters 20060213 |
| Activation of mitochondrial ATP-sensitive potassium channels improves rotenone-related motor and neurochemical alterations in rats. | The international journal of neuropsychopharmacology 20060201 |
| A delivery strategy for rotenone microspheres in an animal model of Parkinson's disease. | Biomaterials 20060201 |
| Glatiramer acetate induces pro-apoptotic mechanisms involving Bcl-2, Bax and Cyt-c in peripheral lymphocytes from multiple sclerosis patients. | Journal of neurology 20060201 |
| Mitochondrial production of oxidants is necessary for physiological calcium oscillations. | Journal of cellular physiology 20060201 |
| Thioredoxin-ASK1 complex levels regulate ROS-mediated p38 MAPK pathway activity in livers of aged and long-lived Snell dwarf mice. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060201 |
| The ROS production induced by a reverse-electron flux at respiratory-chain complex 1 is hampered by metformin. | Journal of bioenergetics and biomembranes 20060201 |
| Characteristics of manganese (Mn) transport in rat brain endothelial (RBE4) cells, an in vitro model of the blood-brain barrier. | Neurotoxicology 20060101 |
| Mode of mitochondrial Ca2+ clearance and its influence on secretory responses in stimulated chromaffin cells. | Cell calcium 20060101 |
| Botanical insecticides, deterrents, and repellents in modern agriculture and an increasingly regulated world. | Annual review of entomology 20060101 |
| Mechanism of toxicity of the branched-chain fatty acid phytanic acid, a marker of Refsum disease, in astrocytes involves mitochondrial impairment. | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20060101 |
| A dip in the chlorophyll fluorescence induction at 0.2-2 s in Trebouxia-possessing lichens reflects a fast reoxidation of photosystem I. A comparison with higher plants. | Biochimica et biophysica acta 20060101 |
| Rotenone produces opposite effects upon mouse striatal dopamine function as a result of environmental temperature. | Neurotoxicity research 20060101 |
| Methylene blue prevents neurodegeneration caused by rotenone in the retina. | Neurotoxicity research 20060101 |
| S-nitrosothiol inhibition of mitochondrial complex I causes a reversible increase in mitochondrial hydrogen peroxide production. | Biochimica et biophysica acta 20060101 |
| Production of reactive oxygen species in mitochondria of HeLa cells under oxidative stress. | Biochimica et biophysica acta 20060101 |
| Generation of superoxide by the mitochondrial Complex I. | Biochimica et biophysica acta 20060101 |
| Neural repair strategies for Parkinson's disease: insights from primate models. | Cell transplantation 20060101 |
| Pharmacologic reductions of total tau levels; implications for the role of microtubule dynamics in regulating tau expression. | Molecular neurodegeneration 20060101 |
| The rotenone model of parkinsonism--the five years inspection. | Journal of neural transmission. Supplementum 20060101 |
| Controversies on new animal models of Parkinson's disease pro and con: the rotenone model of Parkinson's disease (PD). | Journal of neural transmission. Supplementum 20060101 |
| [Role of mitochondria in reglulation of endothelial cell hyperpolarization to acetylcholine]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20060101 |
| Similar patterns of mitochondrial vulnerability and rescue induced by genetic modification of alpha-synuclein, parkin, and DJ-1 in Caenorhabditis elegans. | The Journal of biological chemistry 20051230 |
| Rotenone model of Parkinson disease: multiple brain mitochondria dysfunctions after short term systemic rotenone intoxication. | The Journal of biological chemistry 20051223 |
| Valproic acid-mediated Hsp70 induction and anti-apoptotic neuroprotection in SH-SY5Y cells. | FEBS letters 20051219 |
| Effect of fraxetin on antioxidant defense and stress proteins in human neuroblastoma cell model of rotenone neurotoxicity. Comparative study with myricetin and N-acetylcysteine. | Toxicology and applied pharmacology 20051215 |
| Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function. | Human molecular genetics 20051215 |
| Small interfering RNA targeting the PINK1 induces apoptosis in dopaminergic cells SH-SY5Y. | Biochemical and biophysical research communications 20051202 |
| Dopaminergic neurotoxins require excitotoxic stimulation in organotypic cultures. | Neurobiology of disease 20051201 |
| Rotenone and CCCP inhibit tyrosine hydroxylation in rat striatal tissue slices. | Toxicology 20051201 |
| Efficacy of deguelin and silibinin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice. | Neoplasia (New York, N.Y.) 20051201 |
| Mitochondrial manganese-superoxide dismutase expression in ovarian cancer: role in cell proliferation and response to oxidative stress. | The Journal of biological chemistry 20051125 |
| AMP-activated protein kinase alpha2 activity is not essential for contraction- and hyperosmolarity-induced glucose transport in skeletal muscle. | The Journal of biological chemistry 20051125 |
| Deguelin as a chemopreventive agent in mouse lung tumorigenesis induced by tobacco smoke carcinogens. | Journal of the National Cancer Institute 20051116 |
| Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesis. | Journal of the National Cancer Institute 20051116 |
| Fast and versatile multiresidue method for the analysis of botanical insecticides on fruits and vegetables by HPLC/DAD/MS. | Journal of agricultural and food chemistry 20051102 |
| Paraquat neurotoxicity is distinct from that of MPTP and rotenone. | Toxicological sciences : an official journal of the Society of Toxicology 20051101 |
| The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathy. | Journal of neurochemistry 20051101 |
| Morphine modulation of the ubiquitin-proteasome complex is neuroprotective. | Medical science monitor : international medical journal of experimental and clinical research 20051101 |
| Partial mitochondrial inhibition causes striatal dopamine release suppression and medium spiny neuron depolarization via H2O2 elevation, not ATP depletion. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20051026 |
| Novel inhibitors of the mitochondrial respiratory chain: oximes and pyrrolines isolated from Penicillium brevicompactum and synthetic analogues. | Journal of agricultural and food chemistry 20051019 |
| Hypertonic induction of COX-2 in collecting duct cells by reactive oxygen species of mitochondrial origin. | The Journal of biological chemistry 20051014 |
| Death-associated protein kinase as a sensor of mitochondrial membrane potential: role of lysosome in mitochondrial toxin-induced cell death. | The Journal of biological chemistry 20051014 |
| Selective vulnerability of dopaminergic neurons to microtubule depolymerization. | The Journal of biological chemistry 20051007 |
| Oxidative phosphorylation and the tricarboxylic acid cycle are essential for normal development of mouse ovarian follicles. | Human reproduction (Oxford, England) 20051001 |
| Oxygen-sensing pathway for SK channels in the ovine adrenal medulla. | Clinical and experimental pharmacology & physiology 20051001 |
| Deguelin regulates nuclear pore complex proteins Nup98 and Nup88 in U937 cells in vitro. | Acta pharmacologica Sinica 20051001 |
| Induction of apoptosis-like mitochondrial impairment triggers antioxidant and Bcl-2-dependent keratinocyte differentiation. | The Journal of investigative dermatology 20051001 |
| Vitamin C enters mitochondria via facilitative glucose transporter 1 (Glut1) and confers mitochondrial protection against oxidative injury. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051001 |
| Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease. | Current biology : CB 20050906 |
| Mitochondrial respiration and ATP production are significantly impaired in striatal cells expressing mutant huntingtin. | The Journal of biological chemistry 20050902 |
| Mitochondrial reactive oxygen species and c-Src play a critical role in hypoxic response in vascular smooth muscle cells. | Cardiovascular research 20050901 |
| Fraxetin prevents rotenone-induced apoptosis by induction of endogenous glutathione in human neuroblastoma cells. | Neuroscience research 20050901 |
| Mitochondrial dysfunction in choline deficiency-induced apoptosis in cultured rat hepatocytes. | Free radical biology & medicine 20050901 |
| Early environmental origins of neurodegenerative disease in later life. | Environmental health perspectives 20050901 |
| Depressant effect of mitochondrial respiratory complex inhibitors on proteasome inhibitor-induced mitochondrial dysfunction and cell death in PC12 cells. | Neurochemical research 20050901 |
| Mitochondria-derived reactive oxygen species dilate cerebral arteries by activating Ca2+ sparks. | Circulation research 20050819 |
| Oxidized LDL induces mitochondrially associated reactive oxygen/nitrogen species formation in endothelial cells. | American journal of physiology. Heart and circulatory physiology 20050801 |
| Reactive oxygen species are essential mediators in antigen presentation by Kupffer cells. | Immunology and cell biology 20050801 |
| Analysis of mitochondrial membrane potential in the cells by microchip flow cytometry. | Electrophoresis 20050801 |
| Rotenoids and isoflavones from Sarcolobus globosus. | Planta medica 20050801 |
| Behavioral differences in a rotenone-induced hemiparkinsonian rat model developed following intranigral or median forebrain bundle infusion. | Brain research 20050727 |
| Estrogen-induced G1/S transition of G0-arrested estrogen-dependent breast cancer cells is regulated by mitochondrial oxidant signaling. | Oncogene 20050721 |
| PACAP protects neuronal differentiated PC12 cells against the neurotoxicity induced by a mitochondrial complex I inhibitor, rotenone. | FEBS letters 20050718 |
| Targeting the NAD7 subunit to mitochondria restores a functional complex I and a wild type phenotype in the Nicotiana sylvestris CMS II mutant lacking nad7. | The Journal of biological chemistry 20050715 |
| Inhibitor studies on non-photochemical plastoquinone reduction and H(2) photoproduction in Chlamydomonas reinhardtii. | Biochimica et biophysica acta 20050715 |
| Larvicidal and adulticidal activity of alkylphthalide derivatives from rhizome of Cnidium officinale against Drosophila melanogaster. | Journal of agricultural and food chemistry 20050713 |
| Acute intranigral infusion of rotenone in rats causes progressive biochemical lesions in the striatum similar to Parkinson's disease. | Brain research 20050712 |
| Effect of sildenafil citrate and a nitric oxide donating sildenafil derivative, NCX 911, on cavernosal relaxation and superoxide formation in hypercholesterolaemic rabbits. | European journal of pharmacology 20050711 |
| Reactive oxygen species from smooth muscle mitochondria initiate cold-induced constriction of cutaneous arteries. | American journal of physiology. Heart and circulatory physiology 20050701 |
| Effects of menadione and its derivative on cultured cardiomyocytes with mitochondrial disorders. | Journal of molecular and cellular cardiology 20050701 |
| Increased sensitivity of striatal dopamine release to H2O2 upon chronic rotenone treatment. | Free radical biology & medicine 20050701 |
| Regulating expressions of cyclin D1, pRb, and anti-cancer effects of deguelin on human Burkitt's lymphoma Daudi cells in vitro. | Acta pharmacologica Sinica 20050701 |
| Processes and components participating in the generation of intrinsic optical signal changes in vitro. | The European journal of neuroscience 20050701 |
| Role of mitochondria in the regulation of hypoxia-inducible factor-1alpha in the rat carotid body glomus cells. | Histochemistry and cell biology 20050701 |
| Toxin-induced models of Parkinson's disease. | NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 20050701 |
| Stress-induced activation of the p53 tumor suppressor in leukemia cells and normal lymphocytes requires mitochondrial activity and reactive oxygen species. | Blood 20050615 |
| Hypoxic augmentation of Ca2+ channel currents requires a functional electron transport chain. | The Journal of biological chemistry 20050610 |
| Inhibition of complex I of the electron transport chain causes O2-. -mediated mitochondrial outgrowth. | American journal of physiology. Cell physiology 20050601 |
| Purine nucleoside-mediated protection of chemical hypoxia-induced neuronal injuries involves p42/44 MAPK activation. | Neurochemistry international 20050601 |
| Increased myocardial N-myristoyltransferase activity in rotenone model of Parkinsonism. | International journal of molecular medicine 20050601 |
| Deguelin, A PI3K/AKT inhibitor, enhances chemosensitivity of leukaemia cells with an active PI3K/AKT pathway. | British journal of haematology 20050601 |
| Mitochondrial membrane depolarization and the selective death of dopaminergic neurons by rotenone: protective effect of coenzyme Q10. | Journal of neurochemistry 20050601 |
| Isolation and structural elucidation of a novel rotenoid from the seeds of Clitoria fairchildiana. | Natural product research 20050601 |
| Effect of deguelin on UVB-induced skin carcinogenesis. | Journal of chemotherapy (Florence, Italy) 20050601 |
| Angiotensin II protects cultured midbrain dopaminergic neurons against rotenone-induced cell death. | Brain research 20050531 |
| Sleep disturbances in the rotenone animal model of Parkinson disease. | Brain research 20050503 |
| Systematic administration of iptakalim, an ATP-sensitive potassium channel opener, prevents rotenone-induced motor and neurochemical alterations in rats. | Journal of neuroscience research 20050501 |
| Ca2+-induced permeabilization promotes free radical release from rat brain mitochondria with partially inhibited complex I. | Journal of neurochemistry 20050501 |
| Rotenone induces oxidative stress and dopaminergic neuron damage in organotypic substantia nigra cultures. | Brain research. Molecular brain research 20050324 |
| Resistance to endotoxic shock in endothelial nitric-oxide synthase (eNOS) knock-out mice: a pro-inflammatory role for eNOS-derived no in vivo. | The Journal of biological chemistry 20050318 |
| Possible involvement of Ca2+ signaling in rotenone-induced apoptosis in human neuroblastoma SH-SY5Y cells. | Neuroscience letters 20050311 |
| Inducers of oxidative stress block ciliary neurotrophic factor activation of Jak/STAT signaling in neurons. | Journal of neurochemistry 20050301 |
| 7a-O-methyldeguelol, a modified rotenoid with an open ring-C, from the roots of Derris trifoliata. | Phytochemistry 20050301 |
| Mitochondrial O2*- and H2O2 mediate glucose deprivation-induced stress in human cancer cells. | The Journal of biological chemistry 20050211 |
| Neuroprotective effect of 1-methyl-1,2,3,4-tetrahydroisoquinoline on cultured rat mesencephalic neurons in the presence or absence of various neurotoxins. | Brain research 20050208 |
| Rotenone-induced caspase 9/3-independent and -dependent cell death in undifferentiated and differentiated human neural stem cells. | Journal of neurochemistry 20050201 |
| Hyperglycemia activates JAK2 signaling pathway in human failing myocytes via angiotensin II-mediated oxidative stress. | Diabetes 20050201 |
| A preferential role for glycolysis in preventing the anoxic depolarization of rat hippocampal area CA1 pyramidal cells. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050126 |
| Prostaglandin F2alpha potentiates the calcium dependent activation of mitochondrial metabolism in luteal cells. | Cell calcium 20050101 |
| Inhibition of MPP+-induced mitochondrial damage and cell death by trifluoperazine and W-7 in PC12 cells. | Neurochemistry international 20050101 |
| Effect of sesamin in Acanthopanax senticosus HARMS on behavioral dysfunction in rotenone-induced parkinsonian rats. | Biological & pharmaceutical bulletin 20050101 |
| Redox regulation of p38 MAPK activation and expression of ICAM-1 and heme oxygenase-1 in human alveolar epithelial (A549) cells. | Antioxidants & redox signaling 20050101 |
| Intracellular dopamine oxidation mediates rotenone-induced apoptosis in PC12 cells. | Acta pharmacologica Sinica 20050101 |
| The results of five coded compounds: genistein, metaproterenol, rotenone, p-anisidine and resorcinol tested in the pH 6.7 Syrian hamster embryo cell morphological transformation assay. | Mutagenesis 20050101 |
| H2O2-induced changes in mitochondrial activity in isolated mouse pancreatic acinar cells. | Molecular and cellular biochemistry 20050101 |
| In vitro search for synergy between flavonoids and epirubicin on multidrug-resistant cancer cells. | In vivo (Athens, Greece) 20050101 |
| The effect of endogenous dopamine in rotenone-induced toxicity in PC12 cells. | Antioxidants & redox signaling 20050101 |
| Energy status, ubiquitin proteasomal function, and oxidative stress during chronic and acute complex I inhibition with rotenone in mesencephalic cultures. | Antioxidants & redox signaling 20050101 |
| Rotenone induces aggregation of gamma-tubulin protein and subsequent disorganization of the centrosome: relevance to formation of inclusion bodies and neurodegeneration. | Neuroscience 20050101 |
| Fatality after deliberate ingestion of the pesticide rotenone: a case report. | Critical care (London, England) 20050101 |
| Protective effect of melatonin on rotenone plus Ca2+-induced mitochondrial oxidative stress and PC12 cell death. | Antioxidants & redox signaling 20050101 |
| [Respiration of wheat root cells under simultaneous inhibition of parts I and III of the electron transport chain of mitochondria by rotenone and antimycine A]. | Tsitologiia 20050101 |
| Mitochondrial activation and the pyruvate paradox in a human cell line. | FEBS letters 20041217 |
| Mitochondrial complex I inhibition depletes plasma testosterone in the rotenone model of Parkinson's disease. | Physiology & behavior 20041215 |
| Distinct mechanisms of neurodegeneration induced by chronic complex I inhibition in dopaminergic and non-dopaminergic cells. | The Journal of biological chemistry 20041210 |
| Cd2+ versus Ca2+-produced mitochondrial membrane permeabilization: a proposed direct participation of respiratory complexes I and III. | Chemico-biological interactions 20041207 |
| Trichomonas hydrogenosomes contain the NADH dehydrogenase module of mitochondrial complex I. | Nature 20041202 |
| Rotenone induces apoptosis via activation of bad in human dopaminergic SH-SY5Y cells. | The Journal of pharmacology and experimental therapeutics 20041201 |
| Selective modulation of ligand-gated P2X purinoceptor channels by acute hypoxia is mediated by reactive oxygen species. | Molecular pharmacology 20041201 |
| The effect of rotenone on the urinary ethanol cycle in rats fed ethanol intragastrically. | Experimental and molecular pathology 20041201 |
| Rotenone potentiates dopamine neuron loss in animals exposed to lipopolysaccharide prenatally. | Experimental neurology 20041201 |
| Lipopolysaccharide induces matrix metalloproteinase-9 expression via a mitochondrial reactive oxygen species-p38 kinase-activator protein-1 pathway in Raw 264.7 cells. | Journal of immunology (Baltimore, Md. : 1950) 20041201 |
| Pramipexole protects against apoptotic cell death by non-dopaminergic mechanisms. | Journal of neurochemistry 20041201 |
| Strong calcium entry activates mitochondrial superoxide generation, upregulating kinase signaling in hippocampal neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20041201 |
| Chronic exposure to rotenone models sporadic Parkinson's disease in Drosophila melanogaster. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20041201 |
| Assay and subcellular localization of pyrroline-5-carboxylate dehydrogenase in rat liver. | Biochimica et biophysica acta 20041118 |
| Blockade of electron transport during ischemia protects cardiac mitochondria. | The Journal of biological chemistry 20041112 |
| Induction and inhibition of aromatase (CYP19) activity by natural and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells. | Toxicological sciences : an official journal of the Society of Toxicology 20041101 |
| The ND1 gene of complex I is a mutational hot spot for Leber's hereditary optic neuropathy. | Annals of neurology 20041101 |
| Pesticides and organic agriculture. | Environmental health perspectives 20041101 |
| Rotenone, deguelin, their metabolites, and the rat model of Parkinson's disease. | Chemical research in toxicology 20041101 |
| Menadione reduces rotenone-induced cell death in cerebellar granule neurons. | Neuroreport 20041005 |
| Leber hereditary optic neuropathy mtDNA mutations disrupt glutamate transport in cybrid cell lines. | Brain : a journal of neurology 20041001 |
| Severe impairment of nucleotide synthesis through inhibition of mitochondrial respiration. | Nucleosides, nucleotides & nucleic acids 20041001 |
| Molecular mechanisms of deguelin-induced apoptosis in transformed human bronchial epithelial cells. | Biochemical pharmacology 20040915 |
| Analysis of alpha-synuclein-associated proteins by quantitative proteomics. | The Journal of biological chemistry 20040910 |
| Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908 |
| Hydrogen peroxide generated at the level of mitochondria in response to peroxynitrite promotes U937 cell death via inhibition of the cytoprotective signalling mediated by cytosolic phospholipase A2. | Cell death and differentiation 20040901 |
| Mitochondrial permeability transition in neuronal damage promoted by Ca2+ and respiratory chain complex II inhibition. | Journal of neurochemistry 20040901 |
| Coordinated behavior of mitochondria in both space and time: a reactive oxygen species-activated wave of mitochondrial depolarization. | Biophysical journal 20040901 |
| Autofluorescence lifetime imaging of cultivated cells using a UV picosecond laser diode. | Journal of fluorescence 20040901 |
| Protective effects of erdosteine on rotenone-induced oxidant injury in liver tissue. | Toxicology and industrial health 20040901 |
| L-DOPA reverses the hypokinetic behaviour and rigidity in rotenone-treated rats. | Behavioural brain research 20040831 |
| Segregation pattern and biochemical effect of the G3460A mtDNA mutation in 27 members of LHON family. | Journal of the neurological sciences 20040830 |
| Stimulators of AMP-activated protein kinase inhibit the respiratory burst in human neutrophils. | FEBS letters 20040827 |
| Parkin protects human dopaminergic neuroblastoma cells against dopamine-induced apoptosis. | Human molecular genetics 20040815 |
| Mitochondrial function is required for hydrogen peroxide-induced growth factor receptor transactivation and downstream signaling. | The Journal of biological chemistry 20040813 |
| Intracellular pH and KATP channel activity in dorsal vagal neurons of juvenile rats in situ during metabolic disturbances. | Brain research 20040813 |
| Effects of iptakalim on rotenone-induced cytotoxicity and dopamine release from PC12 cells. | Neuroscience letters 20040805 |
| Effect of uncouplers on endogenous respiration and ferrous iron oxidation in a chemolithoautotrophic bacterium Acidithiobacillus (Thiobacillus) ferrooxidans. | FEMS microbiology letters 20040801 |
| Growth inhibition dependent on reactive oxygen species generated by C9-UK-2A, a derivative of the antifungal antibiotic UK-2A, in Saccharomyces cerevisiae. | The Journal of antibiotics 20040801 |
| Effects of mitochondrial dysfunction on glutamate receptor-mediated neurotoxicity in cultured rat spinal motor neurons. | Brain research 20040723 |
| Apoptosis induction by the natural product cancer chemopreventive agent deguelin is mediated through the inhibition of mitochondrial bioenergetics. | Apoptosis : an international journal on programmed cell death 20040701 |
| Cadmium induces caspase-independent apoptosis in liver Hep3B cells: role for calcium in signaling oxidative stress-related impairment of mitochondria and relocation of endonuclease G and apoptosis-inducing factor. | Free radical biology & medicine 20040615 |
| Rotenone-sensitive mitochondrial potential in Phytomonas serpens: electrophoretic Ca(2+) accumulation. | Biochimica et biophysica acta 20040607 |
| Protective effect of 1-methyl-1,2,3,4-tetrahydroisoquinoline against dopaminergic neurodegeneration in the extrapyramidal structures produced by intracerebral injection of rotenone. | The international journal of neuropsychopharmacology 20040601 |
| Stable compounds of cigarette smoke induce endothelial superoxide anion production via NADPH oxidase activation. | Arteriosclerosis, thrombosis, and vascular biology 20040601 |
| Inverse gene expression patterns for macrophage activating hepatotoxicants and peroxisome proliferators in rat liver. | Biochemical pharmacology 20040601 |
| Behavioral and immunohistochemical effects of chronic intravenous and subcutaneous infusions of varying doses of rotenone. | Experimental neurology 20040601 |
| Proximal tubular cytochrome c efflux: determinant, and potential marker, of mitochondrial injury. | Kidney international 20040601 |
| Race-specific differences in endothelial function: predisposition of African Americans to vascular diseases. | Circulation 20040601 |
| Cancer chemopreventive activity of rotenoids from Derris trifoliata. | Planta medica 20040601 |
| Neuroprotective effect of fraxetin and myricetin against rotenone-induced apoptosis in neuroblastoma cells. | Brain research 20040529 |
| Partial reconstruction of in vitro gluconeogenesis arising from mitochondrial l-lactate uptake/metabolism and oxaloacetate export via novel L-lactate translocators. | The Biochemical journal 20040515 |
| Oxidation and reduction of pyridine nucleotides in alamethicin-permeabilized plant mitochondria. | The Biochemical journal 20040515 |
| 1-Benzyl-1,2,3,4-tetrahydroisoquinoline, a Parkinsonism-inducing endogenous toxin, increases alpha-synuclein expression and causes nuclear damage in human dopaminergic cells. | Journal of neuroscience research 20040515 |
| The neurobehavioral changes induced by bilateral rotenone lesion in medial forebrain bundle of rats are reversed by L-DOPA. | Behavioural brain research 20040505 |
| Mitochondrial modulation of Ca2+ sparks and transient KCa currents in smooth muscle cells of rat cerebral arteries. | The Journal of physiology 20040501 |
| Rotenone-induced apoptosis is mediated by p38 and JNK MAP kinases in human dopaminergic SH-SY5Y cells. | Toxicological sciences : an official journal of the Society of Toxicology 20040501 |
| The value of DNA methylation analysis in basic, initial toxicity assessments. | Toxicological sciences : an official journal of the Society of Toxicology 20040501 |
| Opening of the mitochondrial permeability transition pore induces reactive oxygen species production at the level of the respiratory chain complex I. | The Journal of biological chemistry 20040423 |
| Redox activity associated with the maturation and capacitation of mammalian spermatozoa. | Free radical biology & medicine 20040415 |
| Preservation of complex I function during hypoxia-reoxygenation-induced mitochondrial injury in proximal tubules. | American journal of physiology. Renal physiology 20040401 |
| The effect of mitochondrial inhibitors on membrane currents in isolated neonatal rat carotid body type I cells. | The Journal of physiology 20040401 |
| Rotenone induces non-specific central nervous system and systemic toxicity. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040401 |
| Striatal cells from mutant huntingtin knock-in mice are selectively vulnerable to mitochondrial complex II inhibitor-induced cell death through a non-apoptotic pathway. | Human molecular genetics 20040401 |
| Chronic administration of rotenone increases levels of nitric oxide and lipid peroxidation products in rat brain. | Experimental neurology 20040401 |
| Thiazolidinediones, like metformin, inhibit respiratory complex I: a common mechanism contributing to their antidiabetic actions? | Diabetes 20040401 |
| Reactive oxygen species amplify protein kinase C signaling in high glucose-induced fibronectin expression by human peritoneal mesothelial cells. | Kidney international 20040401 |
| Abnormal alpha-synuclein interactions with Rab proteins in alpha-synuclein A30P transgenic mice. | Journal of neuropathology and experimental neurology 20040401 |
| Proteasome mediates dopaminergic neuronal degeneration, and its inhibition causes alpha-synuclein inclusions. | The Journal of biological chemistry 20040312 |
| NADH oxidase activity of rat cardiac sarcoplasmic reticulum regulates calcium-induced calcium release. | Circulation research 20040305 |
| NADH-ubiquinone oxidoreductase activity in the kinetoplasts of the plant trypanosomatid Phytomonas serpens. | Parasitology research 20040301 |
| Assay of mitochondrial functions by resazurin in vitro. | Acta pharmacologica Sinica 20040301 |
| Cytotoxic compounds from Mundulea chapelieri from the Madagascar Rainforest. | Journal of natural products 20040301 |
| Purine nucleosides support the neurite outgrowth of primary rat cerebellar granule cells after hypoxia. | European journal of cell biology 20040301 |
| Clearance of alpha-synuclein oligomeric intermediates via the lysosomal degradation pathway. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040225 |
| Deguelin-induced inhibition of cyclooxygenase-2 expression in human bronchial epithelial cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040201 |
| Rotenone and rotenoids in cubè resins, formulations, and residues on olives. | Journal of agricultural and food chemistry 20040128 |
| Analysis of the mechanism by which calcium negatively regulates the tyrosine phosphorylation cascade associated with sperm capacitation. | Journal of cell science 20040115 |
| Photodynamic inhibition of enzymatic detachment of human cancer cells from a substratum. | Biochimica et biophysica acta 20040105 |
| Oxidative phosphorylation and rotenone-insensitive malate- and NADH-quinone oxidoreductases in Plasmodium yoelii yoelii mitochondria in situ. | The Journal of biological chemistry 20040102 |
| Rotenone induces disassembly of the Golgi apparatus in the rat dopaminergic neuroblastoma B65 cell line. | Neuroscience letters 20040102 |
| Production of endogenous matrix superoxide from mitochondrial complex I leads to activation of uncoupling protein 3. | FEBS letters 20040102 |
| Early ionic and membrane potential changes caused by the pesticide rotenone in striatal cholinergic interneurons. | Experimental neurology 20040101 |
| Source of early reactive oxygen species in the apoptosis induced by transforming growth factor-beta in fetal rat hepatocytes. | Free radical biology & medicine 20040101 |
| Cancer chemopreventive activity of rotenoids from Derris trifoliata. | Planta medica 20040101 |
| The modulation of action potential generation by calcium-induced calcium release is enhanced by mitochondrial inhibitors in mudpuppy parasympathetic neurons. | Neuroscience 20040101 |
| Valproic acid uptake by bovine brain microvessel endothelial cells: role of active efflux transport. | Epilepsy research 20040101 |
| Antimycin A treatment decreases respiratory internal rotenone-insensitive NADH oxidation capacity in potato leaves. | BMC plant biology 20040101 |
| Mutation in mitochondrial complex I ND6 subunit is associated with defective response to hypoxia in human glioma cells. | Molecular cancer 20040101 |
| Sensitivity of zebrafish to environmental toxins implicated in Parkinson's disease. | Neurotoxicology and teratology 20040101 |
| [Rotenone-insensitive NADH oxydation in mitochondrial suspension occurs by NADH dehydrogenase of respiratory chain fragments]. | Biofizika 20040101 |
| [Ultrastructural characteristics of mitochondria during cell adaptation to rotenone]. | Tsitologiia 20040101 |
| Rotenone, a mitochondrial electron transport inhibitor, ameliorates ischemia-reperfusion-induced intestinal mucosal damage in rats. | Redox report : communications in free radical research 20040101 |
| Caenorhabditis elegans MPP+ model of Parkinson's disease for high-throughput drug screenings. | Neuro-degenerative diseases 20040101 |
| Redox-dependent modulation of aconitase activity in intact mitochondria. | Biochemistry 20031223 |
| Dopamine is involved in selectivity of dopaminergic neuronal death by rotenone. | Neuroreport 20031219 |
| Effects of mitochondrial inhibitors and uncouplers on hypoxic vasoconstriction in rabbit lungs. | American journal of respiratory cell and molecular biology 20031201 |
| Proximal tubular cholesterol loading after mitochondrial, but not glycolytic, blockade. | American journal of physiology. Renal physiology 20031201 |
| Rotenone increases glutamate-induced dopamine release but does not affect hydroxyl-free radical formation in rat striatum. | Synapse (New York, N.Y.) 20031201 |
| MPP+ analogs acting on mitochondria and inducing neuro-degeneration. | Current medicinal chemistry 20031201 |
| Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis. | Free radical biology & medicine 20031201 |
| Cytosol-mitochondria transfer of reducing equivalents by a lactate shuttle in heterotrophic Euglena. | European journal of biochemistry 20031201 |
| Mitochondrial cytochrome c release mediates ceramide-induced activator protein 2 activation and gene expression in keratinocytes. | The Journal of biological chemistry 20031128 |
| Mechanism of toxicity in rotenone models of Parkinson's disease. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20031126 |
| Inhibitory effects on mitochondrial complex I of semisynthetic mono-tetrahydrofuran acetogenin derivatives. | Bioorganic & medicinal chemistry letters 20031117 |
| An inhibitor of mitochondrial complex I, rotenone, inactivates proteasome by oxidative modification and induces aggregation of oxidized proteins in SH-SY5Y cells. | Journal of neuroscience research 20031115 |
| Mechanism for generation of hydrogen peroxide and change of mitochondrial membrane potential during rotenone-induced apoptosis. | Life sciences 20031107 |
| Alpha-synuclein expression in HEK293 cells enhances the mitochondrial sensitivity to rotenone. | Neuroscience letters 20031106 |
| Fe(II)-induced DNA damage in alpha-synuclein-transfected human dopaminergic BE(2)-M17 neuroblastoma cells: detection by the Comet assay. | Journal of neurochemistry 20031101 |
| Mode of action of pyrazinamide: disruption of Mycobacterium tuberculosis membrane transport and energetics by pyrazinoic acid. | The Journal of antimicrobial chemotherapy 20031101 |
| The pesticide rotenone induces caspase-3-mediated apoptosis in ventral mesencephalic dopaminergic neurons. | Journal of neurochemistry 20031101 |
| Concise synthesis of the chemopreventitive agent (+/-)-deguelin via a key 6-endo hydroarylation. | Organic letters 20031030 |
| An increase in intracellular calcium concentration that is induced by basolateral CO2 in rabbit renal proximal tubule. | American journal of physiology. Renal physiology 20031001 |
| Alterations of mitochondria in peripheral blood mononuclear cells of vitiligo patients. | Pigment cell research 20031001 |
| Hypoxia and stretch regulate intercellular communication in vascular smooth muscle cells through reactive oxygen species formation. | Arteriosclerosis, thrombosis, and vascular biology 20031001 |
| Anti-plasmodial activities and X-ray crystal structures of rotenoids from Millettia usaramensis subspecies usaramensis. | Phytochemistry 20031001 |
| Agonist-induced calcium and oxidative stress responses in endothelial cells. | Biochemical Society transactions 20031001 |
| Mechanism of primary Cd2+-induced rat liver mitochondria dysfunction: discrete modes of Cd2+ action on calcium and thiol-dependent domains. | Toxicology and applied pharmacology 20031001 |
| Control of ascorbate synthesis by respiration and its implications for stress responses. | Plant physiology 20031001 |
| Effect of rotenoids from the seeds of Millettia dura on larvae of Aedes aegypti. | Pest management science 20031001 |
| The production of reactive oxygen species in intact isolated nerve terminals is independent of the mitochondrial membrane potential. | Neurochemical research 20031001 |
| Sources for superoxide release: lessons from blockade of electron transport, NADPH oxidase, and anion channels in diaphragm. | Antioxidants & redox signaling 20031001 |
| NF-E2-related factor-2 mediates neuroprotection against mitochondrial complex I inhibitors and increased concentrations of intracellular calcium in primary cortical neurons. | The Journal of biological chemistry 20030926 |
| Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism. | The Journal of biological chemistry 20030926 |
| Production of reactive oxygen species by mitochondria: central role of complex III. | The Journal of biological chemistry 20030919 |
| Mitochondrial sources of H2O2 generation play a key role in flow-mediated dilation in human coronary resistance arteries. | Circulation research 20030919 |
| Stimulation by surangin B of endogenous amino acid release from synaptosomes. | Toxicon : official journal of the International Society on Toxinology 20030915 |
| Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease. | Journal of neurochemistry 20030901 |
| Role of nitric oxide in rotenone-induced nigro-striatal injury. | Journal of neurochemistry 20030901 |
| Inhibition of preadipocyte proliferation by mitochondrial reactive oxygen species. | FEBS letters 20030828 |
| Vitamin D enhances caspase-dependent and -independent TNFalpha-induced breast cancer cell death: The role of reactive oxygen species and mitochondria. | International journal of cancer 20030820 |
| Differential effects of vitamin E and three hydrophilic antioxidants on the actinomycin D-induced and colcemid-accelerated apoptosis in human leukemia CMK-7 cell line. | Molecular and cellular biochemistry 20030801 |
| Effect of thyroid state on H2O2 production by rat liver mitochondria. | Molecular and cellular endocrinology 20030731 |
| Critical role for microglial NADPH oxidase in rotenone-induced degeneration of dopaminergic neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030716 |
| Effect of fraxetin and myricetin on rotenone-induced cytotoxicity in SH-SY5Y cells: comparison with N-acetylcysteine. | European journal of pharmacology 20030704 |
| Reversal of Bcl-2-mediated resistance of the EW36 human B-cell lymphoma cell line to arsenite- and pesticide-induced apoptosis by PK11195, a ligand of the mitochondrial benzodiazepine receptor. | Toxicological sciences : an official journal of the Society of Toxicology 20030701 |
| Models of Parkinson's disease. | Movement disorders : official journal of the Movement Disorder Society 20030701 |
| Effect of voluntary exercise on H2O2 release by subsarcolemmal and intermyofibrillar mitochondria. | Free radical biology & medicine 20030701 |
| Rotenone alpha-oxime. | Acta crystallographica. Section C, Crystal structure communications 20030701 |
| Effect of electron-transport inhibitors on the generation of reactive oxygen species by pea mitochondria during succinate oxidation. | Biochemistry. Biokhimiia 20030701 |
| Rapid reduction of ATP synthesis and lack of free radical formation by MPP+ in rat brain synaptosomes and mitochondria. | Brain research 20030613 |
| Apoptosis triggered redistribution of caspase-9 from cytoplasm to mitochondria. | FEBS letters 20030605 |
| Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis. | Cell death and differentiation 20030601 |
| Prenylated isoflavonoids from Millettia pervilleana. | Phytochemistry 20030601 |
| K-ATP channel independent effects of pinacidil on ATP production in isolated cardiomyocyte or pancreatic beta-cell mitochondria. | Biochemical pharmacology 20030601 |
| Metallothionein attenuates 3-morpholinosydnonimine (SIN-1)-induced oxidative stress in dopaminergic neurons. | Antioxidants & redox signaling 20030601 |
| 24-well plate spectrophotometric assay for preliminary screening of metabolic activity. | Assay and drug development technologies 20030601 |
| The 9.8 kDa subunit of complex I, related to bacterial Na(+)-translocating NADH dehydrogenases, is required for enzyme assembly and function in Neurospora crassa. | Journal of molecular biology 20030530 |
| Ca2+-induced oxidative stress in brain mitochondria treated with the respiratory chain inhibitor rotenone. | FEBS letters 20030522 |
| Rotenone selectively occludes sensitivity to hypoxia in rat carotid body glomus cells. | The Journal of physiology 20030501 |
| Selective microglial activation in the rat rotenone model of Parkinson's disease. | Neuroscience letters 20030501 |
| Leaf mitochondria modulate whole cell redox homeostasis, set antioxidant capacity, and determine stress resistance through altered signaling and diurnal regulation. | The Plant cell 20030501 |
| Inhibitory activities of three annonaceous acetogenins on NADH oxidase of chicken liver mitochondria. | Biological & pharmaceutical bulletin 20030501 |
| Molecular mechanisms of dopaminergic neurodegeneration: genetic and environmental basis. | Annals of the New York Academy of Sciences 20030501 |
| Circadian rhythms of oxidative phosphorylation: effects of rotenone and melatonin on isolated rat brain mitochondria. | Chronobiology international 20030501 |
| 1-methyl-1,2,3,4-tetrahydroisoquinoline protects against rotenone-induced mortality and biochemical changes in rat brain. | European journal of pharmacology 20030418 |
| Mitochondrial effects with ceramide-induced cardiac apoptosis are different from those of palmitate. | Archives of biochemistry and biophysics 20030415 |
| Tigliane diterpenes from the latex of Euphorbia obtusifolia with inhibitory activity on the mammalian mitochondrial respiratory chain. | Journal of ethnopharmacology 20030401 |
| 1-Methyl-4-phenylpyridinium accumulates in cerebellar granule neurons via organic cation transporter 3. | Journal of neurochemistry 20030401 |
| Deguelin suppresses the formation of carcinogen-induced aberrant crypt foci in the colon of CF-1 mice. | International journal of cancer 20030310 |
| Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production. | The Journal of biological chemistry 20030307 |
| Blue light-induced generation of reactive oxygen species in photoreceptor ellipsoids requires mitochondrial electron transport. | Investigative ophthalmology & visual science 20030301 |
| Activation of mitochondrial ATP-sensitive potassium channels increases cell viability against rotenone-induced cell death. | Journal of neurochemistry 20030301 |
| Signaling of hypoxia-induced autonomous proliferation of endothelial cells. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030301 |
| Rotenone and oxalic acid as alternative acaricidal treatments for Varroa destructor in honeybee colonies. | Veterinary parasitology 20030227 |
| AKT and the phosphatidylinositol 3-kinase/AKT pathway: important molecular targets for lung cancer prevention and treatment. | Journal of the National Cancer Institute 20030219 |
| Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells. | Journal of the National Cancer Institute 20030219 |
| External alternative NADH dehydrogenase of Saccharomyces cerevisiae: a potential source of superoxide. | Free radical biology & medicine 20030215 |
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| Redox signaling in the growth and development of colonial hydroids. | The Journal of experimental biology 20030201 |
| Chronic systemic complex I inhibition induces a hypokinetic multisystem degeneration in rats. | Journal of neurochemistry 20030201 |
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| Determination of rotenone in river water utilizing packed capillary column switching liquid chromatography with UV and time-of-flight mass spectrometric detection. | Journal of chromatography. A 20030103 |
| Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation. | Experimental neurology 20030101 |
| Mitochondrial complex inhibitors preferentially damage substantia nigra dopamine neurons in rat brain slices. | Experimental neurology 20030101 |
| Non-synaptic release of [3H]noradrenaline in response to oxidative stress combined with mitochondrial dysfunction in rat hippocampal slices. | Neuroscience 20030101 |
| Animal models of Parkinson's disease in rodents induced by toxins: an update. | Journal of neural transmission. Supplementum 20030101 |
| The mitochondrial complex I inhibitor annonacin is toxic to mesencephalic dopaminergic neurons by impairment of energy metabolism. | Neuroscience 20030101 |
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| Participation of chloroplasts in plant apoptosis. | Bioscience reports 20030101 |
| Effect of mitochondrial inhibitors on type I cells. | Advances in experimental medicine and biology 20030101 |
| Cytoprotective and anticancer properties of coenzyme Q versus capsaicin. | BioFactors (Oxford, England) 20030101 |
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| Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)+ oxidation-reduction state. | The Biochemical journal 20021201 |
| Prostaglandin A1 inhibits rotenone-induced apoptosis in SH-SY5Y cells. | Journal of neurochemistry 20021201 |
| Deguelin inhibits the growth of colon cancer cells through the induction of apoptosis and cell cycle arrest. | European journal of cancer (Oxford, England : 1990) 20021201 |
| An inflammatory review of Parkinson's disease. | Progress in neurobiology 20021201 |
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| [Genetics and environmental factors of Parkinson disease]. | Revue neurologique 20021201 |
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| Hypoxic but not anoxic stabilization of HIF-1alpha requires mitochondrial reactive oxygen species. | American journal of physiology. Lung cellular and molecular physiology 20021101 |
| CNS neurons express two distinct plasma membrane electron transport systems implicated in neuronal viability. | Journal of neurochemistry 20021101 |
| Synthetic ceramides induce growth arrest or apoptosis by altering cellular redox status. | Archives of biochemistry and biophysics 20021101 |
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| Regulation of hydrogen peroxide production by brain mitochondria by calcium and Bax. | Journal of neurochemistry 20021001 |
| Near UV quantum yields for rotenone and piperonyl butoxide. | The Analyst 20021001 |
| Human mitochondrial thioredoxin. Involvement in mitochondrial membrane potential and cell death. | The Journal of biological chemistry 20020906 |
| Comparison of the effects of ammonia on brain mitochondrial function in rats and gulf toadfish. | American journal of physiology. Regulatory, integrative and comparative physiology 20020901 |
| Mitochondrial-driven bicarbonate transport supports photosynthesis in a marine microalga. | Plant physiology 20020901 |
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| An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020815 |
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| Differences between mouse and rat pancreatic islets: succinate responsiveness, malic enzyme, and anaplerosis. | American journal of physiology. Endocrinology and metabolism 20020801 |
| High glucose stimulates angiotensinogen gene expression via reactive oxygen species generation in rat kidney proximal tubular cells. | Endocrinology 20020801 |
| Modifying effects of dietary capsaicin and rotenone on 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis. | Carcinogenesis 20020801 |
| NADH oxidation and NAD+ reduction catalysed by tightly coupled inside-out vesicles from Paracoccus denitrificans. | European journal of biochemistry 20020801 |
| Role of membrane-associated Ca+ dependent matrix metalloprotease-2 in the oxidant activation of Ca2+Atpase by tertiary butylhydroperoxide. | Molecular and cellular biochemistry 20020801 |
| Expression of mutant alpha-synucleins enhances dopamine transporter-mediated MPP+ toxicity in vitro. | Neuroreport 20020719 |
| Inhibition of the mitochondrial permeability transition by the nonimmunosuppressive cyclosporin derivative NIM811. | Molecular pharmacology 20020701 |
| The fetal and neonatal brain protein neuronatin protects PC12 cells against certain types of toxic insult. | Brain research. Developmental brain research 20020630 |
| Mouse model of optic neuropathy caused by mitochondrial complex I dysfunction. | Neuroscience letters 20020628 |
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| Activation of matrix metalloproteinase-2 by overexpression of manganese superoxide dismutase in human breast cancer MCF-7 cells involves reactive oxygen species. | The Journal of biological chemistry 20020607 |
| Sensory neurons respond to hypoxia with NO production associated with mitochondria. | Molecular and cellular neurosciences 20020601 |
| Protein overload-induced NF-kappaB activation in proximal tubular cells requires H(2)O(2) through a PKC-dependent pathway. | Journal of the American Society of Nephrology : JASN 20020501 |
| Inhibitors of mitochondrial complex I attenuate the accumulation of hypoxia-inducible factor-1 during hypoxia in Hep3B cells. | Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20020501 |
| ATP-driven, Na(+)-independent inward Cl- pumping in neuroblastoma cells. | Journal of neurochemistry 20020501 |
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
| Influence of mitochondrial inhibition on global and local [Ca(2+)](I) in rat tail artery. | Circulation research 20020419 |
| Role of mitochondrial oxidant generation in endothelial cell responses to hypoxia. | Arteriosclerosis, thrombosis, and vascular biology 20020401 |
| Mechanisms of oxygen sensing in human trophoblast cells. | Placenta 20020401 |
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| [Mutagens inducing mutations in mammalian mitochondrial DNA]. | Nihon rinsho. Japanese journal of clinical medicine 20020401 |
| The second coenzyme Q1 binding site of bovine heart NADH: coenzyme Q oxidoreductase. | Journal of bioenergetics and biomembranes 20020401 |
| Coenzyme Q cytoprotective mechanisms for mitochondrial complex I cytopathies involves NAD(P)H: quinone oxidoreductase 1(NQO1). | Free radical research 20020401 |
| Novel FMN-containing rotenone-insensitive NADH dehydrogenase from Trypanosoma brucei mitochondria: isolation and characterization. | Biochemistry 20020305 |
| Antiinflammatory activity of rotenoids from Clitoria fairchildiana. | Phytotherapy research : PTR 20020301 |
| Reactive oxygen species from mitochondria mediate SW480 cells apoptosis induced by Na2SeO3. | Biological trace element research 20020301 |
| The effects of phytochemical pesticides on the growth of cultured invertebrate and vertebrate cells. | Pest management science 20020301 |
| [Modification of the analytical method for rotenoids in plants]. | Se pu = Chinese journal of chromatography 20020301 |
| Lack of contribution of mitochondrial electron transport to acute O(2) sensing in model airway chemoreceptors. | Biochemical and biophysical research communications 20020222 |
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| Control of oxidative phosphorylation by Complex I in rat liver mitochondria: implications for aging. | Biochimica et biophysica acta 20020215 |
| Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020201 |
| Respiration and mitochondrial membrane potential are not required for apoptosis and anti-apoptotic action of Bcl-2 in HeLa cells. | Biochemistry. Biokhimiia 20020201 |
| Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson's disease. | Journal of neurochemistry 20020101 |
| ATP-independent anoxic activation of ATP-sensitive K+ channels in dorsal vagal neurons of juvenile mice in situ. | Neuroscience 20020101 |
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| The targets of 2,2',5,5'-tetrachlorobiphenyl in the respiratory chain of rat liver mitochondria revealed by modular kinetic analysis. | Molecular biology reports 20020101 |
| Transepithelial glucose transport and metabolism in BeWo choriocarcinoma cells. | Placenta 20020101 |
| Selective action of acetogenin mitochondrial complex I inhibitors. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101 |
| Vitamin E succinate protects hepatocytes against the toxic effect of reactive oxygen species generated at mitochondrial complexes I and III by alkylating agents. | Chemico-biological interactions 20011221 |
| Rotenone-induced G2/M cell cycle arrest and apoptosis in a human B lymphoma cell line PW. | Biochemical and biophysical research communications 20011221 |
| Endothelin-1 production is enhanced by rotenone, a mitochondrial complex I inhibitor, in cultured rat cardiomyocytes. | Journal of cardiovascular pharmacology 20011201 |
| The endosomal compartment is an insulin-sensitive recruitment site for GLUT4 and GLUT1 glucose transporters in cardiac myocytes. | Endocrinology 20011201 |
| Opioid receptor modulation of a metabolically sensitive ion channel in rat amygdala neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20011201 |
| Effect of mitochondrial electron transport chain inhibitors on superoxide radical generation in rat hippocampal and striatal slices. | Antioxidants & redox signaling 20011201 |
| Selected presentations and general discussion: session IX summary and research needs. | Neurotoxicology 20011201 |
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| Endothelin-1 stimulates cardiomyocyte injury during mitochondrial dysfunction in culture. | European journal of pharmacology 20011116 |
| Dynamics of intracellular calcium and free radical production during ischemia in pyramidal neurons. | Free radical biology & medicine 20011115 |
| Rotenone inhibits the mitochondrial permeability transition-induced cell death in U937 and KB cells. | The Journal of biological chemistry 20011102 |
| Mammalian TOR: a homeostatic ATP sensor. | Science (New York, N.Y.) 20011102 |
| Chemoprevention of azoxymethane-induced rat colon carcinogenesis by dietary capsaicin and rotenone. | International journal of oncology 20011101 |
| Oxidative stress in scleroderma: maintenance of scleroderma fibroblast phenotype by the constitutive up-regulation of reactive oxygen species generation through the NADPH oxidase complex pathway. | Arthritis and rheumatism 20011101 |
| Stimulation of cardiac glucose transport by inhibitors of oxidative phosphorylation. | Life sciences 20011005 |
| Analysis of reactive oxygen species generating systems in rat epididymal spermatozoa. | Biology of reproduction 20011001 |
| Divergent roles of glycolysis and the mitochondrial electron transport chain in hypoxic pulmonary vasoconstriction of the rat: identity of the hypoxic sensor. | The Journal of physiology 20011001 |
| A flow cytometry assay simultaneously detects independent apoptotic parameters. | Cytometry 20011001 |
| The insecticide target in the PSST subunit of complex I. | Pest management science 20011001 |
| Nickel requires hypoxia-inducible factor-1 alpha, not redox signaling, to induce plasminogen activator inhibitor-1. | American journal of physiology. Lung cellular and molecular physiology 20010901 |
| Mitochondrial electron transport inhibitors cause lipid peroxidation-dependent and -independent cell death: protective role of antioxidants. | Archives of biochemistry and biophysics 20010901 |
| Parkinson disease: etiology, pathogenesis and future of gene therapy. | Neuroscience research 20010901 |
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| H(2)O(2)-induced O(2) production by a non-phagocytic NAD(P)H oxidase causes oxidant injury. | The Journal of biological chemistry 20010803 |
| Mitochondria recycle Ca(2+) to the endoplasmic reticulum and prevent the depletion of neighboring endoplasmic reticulum regions. | The Journal of biological chemistry 20010803 |
| Selective and biphasic effect of the membrane lipid peroxidation product 4-hydroxy-2,3-nonenal on N-methyl-D-aspartate channels. | Journal of neurochemistry 20010801 |
| Development and application of a self-referencing glucose microsensor for the measurement of glucose consumption by pancreatic beta-cells. | Analytical chemistry 20010801 |
| Dependence of excitotoxic neurodegeneration on mitochondrial aconitase inactivation. | Journal of neurochemistry 20010801 |
| Mitochondrial control of inducible nitric oxide production in stimulated RAW 264.7 macrophages. | Antioxidants & redox signaling 20010801 |
| Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain. | Blood 20010715 |
| Functional coupling between the caffeine/ryanodine-sensitive Ca2+ store and mitochondria in rat aortic smooth muscle cells. | The Biochemical journal 20010715 |
| Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A. | The Journal of biological chemistry 20010706 |
| Pesticides directly accelerate the rate of alpha-synuclein fibril formation: a possible factor in Parkinson's disease. | FEBS letters 20010706 |
| Functional coupling of PSST and ND1 subunits in NADH:ubiquinone oxidoreductase established by photoaffinity labeling. | Biochimica et biophysica acta 20010702 |
| Hypoxia-induced upregulation of eNOS gene expression is redox-sensitive: a comparison between hypoxia and inhibitors of cell metabolism. | Journal of cellular physiology 20010701 |
| Modulation of the extracellular divalent cation-inhibited non-selective conductance in cardiac cells by metabolic inhibition and by oxidants. | Journal of molecular and cellular cardiology 20010701 |
| Model for hypoxic pulmonary vasoconstriction involving mitochondrial oxygen sensing. | Circulation research 20010622 |
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| Five new prenylated stilbenes from the root bark of Lonchocarpus chiricanus. | Journal of natural products 20010601 |
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| Mitochondrial respiration and triiodothyronine concentration in liver from postpubertal and adult rats. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20010601 |
| Relaxant effect of 6-deoxyclitoriacetal on smooth muscle preparations. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20010601 |
| Oxidative stress and lipid retention in vascular grafts: comparison between venous and arterial conduits. | Circulation 20010515 |
| Hypersensitization of tumor cells to glycolytic inhibitors. | Biochemistry 20010508 |
| In vitro effects of nicotine on mitochondrial respiration and superoxide anion generation. | Brain research 20010504 |
| Isolation and characterization of complex I, rotenone-sensitive NADH: ubiquinone oxidoreductase, from the procyclic forms of Trypanosoma brucei. | European journal of biochemistry 20010501 |
| Kinetic characterization of the rotenone-insensitive internal NADH: ubiquinone oxidoreductase of mitochondria from Saccharomyces cerevisiae. | Archives of biochemistry and biophysics 20010501 |
| ATP synthesis is coupled to rat liver mitochondrial RNA synthesis. | Molecular and cellular biochemistry 20010501 |
| Selective dopaminergic vulnerability: 3,4-dihydroxyphenylacetaldehyde targets mitochondria. | Free radical biology & medicine 20010415 |
| Calcium-dependent inhibition of L, N, and P/Q Ca2+ channels in chromaffin cells: role of mitochondria. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20010415 |
| Evidence for a quinone binding site close to the interface between NUOD and NUOB subunits of Complex I. | Biochimica et biophysica acta 20010402 |
| A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons. | Journal of neurochemistry 20010401 |
| Regulation of respiration in rotenone-treated tobacco cell suspension cultures. | Planta 20010401 |
| Enhancement of oxidative damage to cultured cells and Caenorhabditis elegans by mitochondrial electron transport inhibitors. | IUBMB life 20010401 |
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| Elevated superoxide production by active H-ras enhances human lung WI-38VA-13 cell proliferation, migration and resistance to TNF-alpha. | Oncogene 20010322 |
| Pharmacokinetics of deguelin, a cancer chemopreventive agent in rats. | Cancer chemotherapy and pharmacology 20010301 |
| Induction of Akt phosphorylation in rat primary astrocytes by H2O2 occurs upstream of phosphatidylinositol 3-kinase: no evidence for oxidative inhibition of PTEN. | Archives of biochemistry and biophysics 20010215 |
| Chronic reduction in complex I function alters calcium signaling in SH-SY5Y neuroblastoma cells. | Brain research 20010209 |
| Dopaminergic cell death induced by MPP(+), oxidant and specific neurotoxicants shares the common molecular mechanism. | Journal of neurochemistry 20010201 |
| Cytoplasmic Ca2+ at low submicromolar concentration stimulates mitochondrial metabolism in rat luteal cells. | Pflugers Archiv : European journal of physiology 20010201 |
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| Mitochondria deficient in complex I activity are depolarized by hydrogen peroxide in nerve terminals: relevance to Parkinson's disease. | Journal of neurochemistry 20010101 |
| Computerized analysis of cytochemical reactions for dehydrogenases and oxygraphic studies as methods to evaluate the function of the mitochondrial sheath in rat spermatozoa. | Andrologia 20010101 |
| Cell attachment modulation by radiation from a pulsed light diode (lambda = 820 nm) and various chemicals. | Lasers in surgery and medicine 20010101 |
| Brain and liver mitochondria isolated from diabetic Goto-Kakizaki rats show different susceptibility to induced oxidative stress. | Diabetes/metabolism research and reviews 20010101 |
| Uncoupling effect of mercuric chloride on mitochondria isolated from an hepatic cell line. | Journal of applied toxicology : JAT 20010101 |
| Tumour necrosis factor induced an early release of superoxide and a late mitochondrial membrane depolarization in L929 cells. Increase in the production of superoxide is not sufficient to mimic the action of TNF. | Biological signals and receptors 20010101 |
| Nitroxide TEMPOL impairs mitochondrial function and induces apoptosis in HL60 cells. | Journal of cellular biochemistry 20010101 |
| Interleukin 1-induced cyclooxygenase and nitric oxide synthase gene expression in the rat dorsal root ganglia is modulated by antioxidants. | Neuroscience 20010101 |
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| The existence and significance of redox-cycling ubiquinone in lysosomes. | Protoplasma 20010101 |
| Mitochondrial-derived oxidants and quartz activation of chemokine gene expression. | Advances in experimental medicine and biology 20010101 |
| Role of substrates in the regulation of mitochondrial function in situ. | IUBMB life 20010101 |
| Optical detection of mitochondrial NADH content in intact human myotubes. | Cellular and molecular biology (Noisy-le-Grand, France) 20010101 |
| Chronic systemic pesticide exposure reproduces features of Parkinson's disease. | Nature neuroscience 20001201 |
| An early oxygen-dependent step is required for dexamethasone-induced apoptosis of immature mouse thymocytes. | Journal of immunology (Baltimore, Md. : 1950) 20001101 |
| Mitochondrial dysfunction of cardiomyocytes causing impairment of cellular energy metabolism induces apoptosis, and concomitant increase in cardiac endothelin-1 expression. | Journal of cardiovascular pharmacology 20001101 |
| Mitochondrial dysfunction increases expression of endothelin-1 and induces apoptosis through caspase-3 activation in rat cardiomyocytes in vitro. | Journal of cardiovascular pharmacology 20001101 |
| Rac1 inhibits TNF-alpha-induced endothelial cell apoptosis: dual regulation by reactive oxygen species. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20000901 |
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| Role of oxidants in NF-kappa B activation and TNF-alpha gene transcription induced by hypoxia and endotoxin. | Journal of immunology (Baltimore, Md. : 1950) 20000715 |
| GLUT-1 reduces hypoxia-induced apoptosis and JNK pathway activation. | American journal of physiology. Endocrinology and metabolism 20000501 |
| Angiotensin II stimulates endothelial vascular cell adhesion molecule-1 via nuclear factor-kappaB activation induced by intracellular oxidative stress. | Arteriosclerosis, thrombosis, and vascular biology 20000301 |
| Sodium arsenate induces overproduction of interleukin-1alpha in murine keratinocytes: role of mitochondria. | The Journal of investigative dermatology 19991101 |
| Diminished energy metabolism and enhanced apoptosis in livers of B6C3F1 mice treated with the antihepatocarcinogen rotenone. | Molecular and cellular biochemistry 19991101 |
| Inhibition of mitochondrial function in HL60 cells is associated with an increased apoptosis and expression of CD14. | Biochemical and biophysical research communications 19990924 |
| Overexpression of manganese superoxide dismutase protects against mitochondrial-initiated poly(ADP-ribose) polymerase-mediated cell death. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19990901 |
| Rotenone and pyruvate prevent the tert-butylhydroperoxide-induced necrosis of U937 cells and allow them to proliferate. | FEBS letters 19990820 |
| Induction of apoptosis in AK-5 cells by rotenone involves participation of caspases. | Indian journal of biochemistry & biophysics 19990401 |
| Alternative sulfonylurea receptor expression defines metabolic sensitivity of K-ATP channels in dopaminergic midbrain neurons. | The EMBO journal 19990215 |
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| Quantitative study of mitochondrial complex I in platelets of parkinsonian patients. | Movement disorders : official journal of the Movement Disorder Society 19980101 |
| Tumor necrosis factor increases hepatocellular glutathione by transcriptional regulation of the heavy subunit chain of gamma-glutamylcysteine synthetase. | The Journal of biological chemistry 19971128 |
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| Regulation of ornithine decarboxylase induction by deguelin, a natural product cancer chemopreventive agent. | Cancer research 19970815 |
| Apoptosis of W256 carcinosarcoma cells of the monocytoid origin induced by NDGA involves lipid peroxidation and depletion of GSH: role of 12-lipoxygenase in regulating tumor cell survival. | Journal of cellular physiology 19970801 |
| Anomalous structure-activity relationships of 13-homo-13-oxarotenoids and 13-homo-13-oxadehyrorotenoids. | Chemical research in toxicology 19970801 |
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