1H-Dibenz[2,3:6,7]oxepino[4,5-c]pyrrole, 5-chloro-2,3,3a,12b-tetrahydro-2-methyl-, trans-, (Z)-2-butenedioate (1:1)
| Title | Journal |
|---|---|
| Newer antipsychotics and upcoming molecules for schizophrenia. | European journal of clinical pharmacology 20130801 |
| Asenapine for the treatment of manic and mixed episodes associated with bipolar I disorder: from clinical research to clinical practice. | Expert opinion on pharmacotherapy 20130301 |
| Asenapine, iloperidone and lurasidone: critical appraisal of the most recently approved pharmacotherapies for schizophrenia in adults. | Expert review of clinical pharmacology 20130101 |
| Development and validation of automated SPE-HPLC-MS/MS methods for the quantification of asenapine, a new antipsychotic agent, and its two major metabolites in human urine. | Biomedical chromatography : BMC 20121201 |
| Iloperidone, asenapine and lurasidone: a primer on their current status. | Expert opinion on pharmacotherapy 20120901 |
| Body weight and metabolic adverse effects of asenapine, iloperidone, lurasidone and paliperidone in the treatment of schizophrenia and bipolar disorder: a systematic review and exploratory meta-analysis. | CNS drugs 20120901 |
| Involvement of 5-HT2A receptor and α2-adrenoceptor blockade in the asenapine-induced elevation of prefrontal cortical monoamine outflow. | Synapse (New York, N.Y.) 20120701 |
| Long-term efficacy and safety of asenapine or olanzapine in patients with schizophrenia or schizoaffective disorder: an extension study. | Pharmacopsychiatry 20120701 |
| ▼Asenapine for bipolar I disorder? | Drug and therapeutics bulletin 20120601 |
| [Asenapine in bipolar disorder: efficacy, safety and place in clinical practice]. | L'Encephale 20120601 |
| Valproate reduces the glucuronidation of asenapine without affecting asenapine plasma concentrations. | Journal of clinical pharmacology 20120501 |
| Short-term safety and pharmacokinetic profile of asenapine in older patients with psychosis. | International journal of geriatric psychiatry 20120501 |
| Asenapine: a clinical review of a second-generation antipsychotic. | Clinical therapeutics 20120501 |
| Asenapine effects on cognitive and monoamine dysfunction elicited by subchronic phencyclidine administration. | Neuropharmacology 20120301 |
| [Antipsychotic medications for bipolar I disorders. New atypical neuroleptic drug asenapine approved]. | Der Nervenarzt 20120301 |
| Quantification of asenapine and three metabolites in human plasma using liquid chromatography-tandem mass spectrometry with automated solid-phase extraction: application to a phase I clinical trial with asenapine in healthy male subjects. | Biomedical chromatography : BMC 20120201 |
| Asenapine as adjunctive treatment for acute mania associated with bipolar disorder: results of a 12-week core study and 40-week extension. | Journal of clinical psychopharmacology 20120201 |
| Asenapine versus olanzapine in people with persistent negative symptoms of schizophrenia. | Journal of clinical psychopharmacology 20120201 |
| Asenapine: a synthesis of efficacy data in bipolar mania and schizophrenia. | Clinical schizophrenia & related psychoses 20120101 |
| Asenapine: a review of acute and extension phase data in bipolar disorder. | CNS neuroscience & therapeutics 20111201 |
| System for disclosing hospitality should be transparent. | BMJ (Clinical research ed.) 20111115 |
| Attenuation of chronic mild stress-induced 'anhedonia' by asenapine is not associated with a 'hedonic' profile in intracranial self-stimulation. | Journal of psychopharmacology (Oxford, England) 20111001 |
| Biological perspectives: update on newer antipsychotic drugs: are they evidence based? | Perspectives in psychiatric care 20111001 |
| Asenapine: a new antipsychotic option. | Journal of pharmacy practice 20111001 |
| Suicidal ideation associated with asenapine use: a report of 2 cases. | Journal of clinical psychopharmacology 20110801 |
| Asenapine pharmacokinetics in hepatic and renal impairment. | Clinical pharmacokinetics 20110701 |
| Unmet treatment needs in schizophrenia patients: is asenapine a potential therapeutic option? | Expert review of neurotherapeutics 20110701 |
| Asenapine for the treatment of stuttering: an analysis of three cases. | The American journal of psychiatry 20110601 |
| Asenapine improves phencyclidine-induced object recognition deficits in the rat: evidence for engagement of a dopamine D1 receptor mechanism. | Psychopharmacology 20110401 |
| Metabolism and excretion of asenapine in healthy male subjects. | Drug metabolism and disposition: the biological fate of chemicals 20110401 |
| Update on newer antipsychotic drugs. | Journal of psychosocial nursing and mental health services 20110401 |
| Dopamine D2 occupancy as a biomarker for antipsychotics: quantifying the relationship with efficacy and extrapyramidal symptoms. | The AAPS journal 20110301 |
| Asenapine: a review of its use in the management of mania in adults with bipolar I disorder. | CNS drugs 20110301 |
| A randomized placebo-controlled trial of asenapine for the prevention of relapse of schizophrenia after long-term treatment. | The Journal of clinical psychiatry 20110301 |
| Iloperidone, asenapine, and lurasidone: a brief overview of 3 new second-generation antipsychotics. | Postgraduate medicine 20110301 |
| Comparison of QTc data analysis methods recommended by the ICH E14 guidance and exposure-response analysis: case study of a thorough QT study of asenapine. | Clinical pharmacology and therapeutics 20110101 |
| Atypical antipsychotics: the two new arrivals. | Issues in mental health nursing 20110101 |
| Effects of asenapine on depressive symptoms in patients with bipolar I disorder experiencing acute manic or mixed episodes: a post hoc analysis of two 3-week clinical trials. | BMC psychiatry 20110101 |
| Asenapine: a clinical overview. | The Journal of clinical psychiatry 20110101 |
| Effects of asenapine, olanzapine, and risperidone on psychotomimetic-induced reversal-learning deficits in the rat. | Behavioural brain research 20101225 |
| Asenapine for long-term treatment of bipolar disorder: a double-blind 40-week extension study. | Journal of affective disorders 20101101 |
| Effects of asenapine on prefrontal N-methyl-D-aspartate receptor-mediated transmission: involvement of dopamine D1 receptors. | Synapse (New York, N.Y.) 20101101 |
| New antipsychotic drugs: how do their receptor-binding profiles compare? | The Journal of clinical psychiatry 20100901 |
| Evaluation of the clinical efficacy of asenapine in schizophrenia. | Expert opinion on pharmacotherapy 20100801 |
| Effect of absorption site on the pharmacokinetics of sublingual asenapine in healthy male subjects. | Biopharmaceutics & drug disposition 20100701 |
| Long-term assessment of Asenapine vs. Olanzapine in patients with schizophrenia or schizoaffective disorder. | Pharmacopsychiatry 20100601 |
| Pharmacology and efficacy of asenapine for manic and mixed states in adults with bipolar disorder. | Expert review of neurotherapeutics 20100501 |
| Repeated effects of asenapine on adrenergic and cholinergic muscarinic receptors. | The international journal of neuropsychopharmacology 20100401 |
| Asenapine in the treatment of acute mania in bipolar I disorder: a randomized, double-blind, placebo-controlled trial. | Journal of affective disorders 20100401 |
| Efficacy and safety of asenapine in a placebo- and haloperidol-controlled trial in patients with acute exacerbation of schizophrenia. | Journal of clinical psychopharmacology 20100401 |
| Asenapine induces differential regional effects on serotonin receptor subtypes. | Journal of psychopharmacology (Oxford, England) 20100301 |
| New drug information. Saphris. | JAAPA : official journal of the American Academy of Physician Assistants 20100301 |
| Asenapine (Saphris) sublingual tablets for schizophrenia and bipolar disorder. | The Medical letter on drugs and therapeutics 20100208 |
| New drugs: asenapine, iloperidone, and bepotastine besilate. | Journal of the American Pharmacists Association : JAPhA 20100101 |
| Asenapine versus olanzapine in acute mania: a double-blind extension study. | Bipolar disorders 20091201 |
| Asenapine for schizophrenia and bipolar disorder: a review of the efficacy and safety profile for this newly approved sublingually absorbed second-generation antipsychotic. | International journal of clinical practice 20091201 |
| Asenapine maleate: a new drug for the treatment of schizophrenia and bipolar mania. | Drugs of today (Barcelona, Spain : 1998) 20091201 |
| Asenapine effects in animal models of psychosis and cognitive function. | Psychopharmacology 20091101 |
| A 3-week, randomized, placebo-controlled trial of asenapine in the treatment of acute mania in bipolar mania and mixed states. | Bipolar disorders 20091101 |
| Exposure-response analysis in patients with schizophrenia to assess the effect of asenapine on QTc prolongation. | Journal of clinical pharmacology 20091101 |
| Asenapine. | Nature reviews. Drug discovery 20091101 |
| Asenapine approved for treatment of schizophrenia, bipolar disorder. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090915 |
| Asenapine. | CNS drugs 20090901 |
| Modeling and simulation of the time course of asenapine exposure response and dropout patterns in acute schizophrenia. | Clinical pharmacology and therapeutics 20090701 |
| Asenapine elevates cortical dopamine, noradrenaline and serotonin release. Evidence for activation of cortical and subcortical dopamine systems by different mechanisms. | Psychopharmacology 20090601 |
| Asenapine exerts distinctive regional effects on ionotropic glutamate receptor subtypes in rat brain. | Synapse (New York, N.Y.) 20090501 |
| Electrophysiological characterization of the effects of asenapine at 5-HT(1A), 5-HT(2A), alpha(2)-adrenergic and D(2) receptors in the rat brain. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20090301 |
| Asenapine: a novel psychopharmacologic agent with a unique human receptor signature. | Journal of psychopharmacology (Oxford, England) 20090101 |
| Asenapine restores cognitive flexibility in rats with medial prefrontal cortex lesions. | Psychopharmacology 20090101 |
| Asenapine increases dopamine, norepinephrine, and acetylcholine efflux in the rat medial prefrontal cortex and hippocampus. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20081101 |
| Differential regional and dose-related effects of asenapine on dopamine receptor subtypes. | Psychopharmacology 20080501 |
| Asenapine, a novel psychopharmacologic agent: preclinical evidence for clinical effects in schizophrenia. | Psychopharmacology 20080201 |
| Efficacy and tolerability of asenapine in acute schizophrenia: a placebo- and risperidone-controlled trial. | The Journal of clinical psychiatry 20071001 |
| Asenapine in the treatment of negative symptoms of schizophrenia: clinical trial design and rationale. | Psychopharmacology bulletin 20070101 |
| Actions of ORG 5222 as a novel psychotropic agent. | Pharmacology, biochemistry, and behavior 19900301 |