Gw2580
| Title | Journal |
|---|---|
| Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer's-like pathology. | Brain : a journal of neurology 20160301 |
| Identification of potent Yes1 kinase inhibitors using a library screening approach. | Bioorganic & medicinal chemistry letters 20130801 |
| A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery. | The Biochemical journal 20130415 |
| Regulation of microglial proliferation during chronic neurodegeneration. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20130206 |
| Role of cell cycle-associated proteins in microglial proliferation in the axotomized rat facial nucleus. | Glia 20120401 |
| Tyrosine kinase inhibitors ameliorate autoimmune encephalomyelitis in a mouse model of multiple sclerosis. | Journal of clinical immunology 20111201 |
| Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity. | Nature biotechnology 20111101 |
| Comprehensive analysis of kinase inhibitor selectivity. | Nature biotechnology 20111030 |
| Discovery, synthesis, and investigation of the antitumor activity of novel piperazinylpyrimidine derivatives. | European journal of medicinal chemistry 20110601 |
| Macrophage-colony stimulating factor and interleukin-34 induce chemokines in human whole blood. | Cytokine 20101201 |
| Activation state-dependent binding of small molecule kinase inhibitors: structural insights from biochemistry. | Chemistry & biology 20101124 |
| Interleukin-34 is expressed by giant cell tumours of bone and plays a key role in RANKL-induced osteoclastogenesis. | The Journal of pathology 20100501 |
| Targeting distinct tumor-infiltrating myeloid cells by inhibiting CSF-1 receptor: combating tumor evasion of antiangiogenic therapy. | Blood 20100218 |
| c-Fms-mediated differentiation and priming of monocyte lineage cells play a central role in autoimmune arthritis. | Arthritis research & therapy 20100101 |
| Effects of the cFMS kinase inhibitor 5-(3-methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine (GW2580) in normal and arthritic rats. | The Journal of pharmacology and experimental therapeutics 20080701 |
| A quantitative analysis of kinase inhibitor selectivity. | Nature biotechnology 20080101 |
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. | Proceedings of the National Academy of Sciences of the United States of America 20071218 |
| Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580. | Proceedings of the National Academy of Sciences of the United States of America 20051101 |