Home Aminos 2,5-Diaminotoluene

2,5-Diaminotoluene

CAS No.:
95-70-5
Catalog Number:
AG003690
Molecular Formula:
C7H10N2
Molecular Weight:
122.1677
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
98%
In Stock USA
United States
$15
- +
5g
98%
In Stock USA
United States
$38
- +
25g
98%
In Stock USA
United States
$119
- +
100g
98%
In Stock USA
United States
$345
- +
Product Description
Catalog Number:
AG003690
Chemical Name:
2,5-Diaminotoluene
CAS Number:
95-70-5
Molecular Formula:
C7H10N2
Molecular Weight:
122.1677
MDL Number:
MFCD00035779
IUPAC Name:
2-methylbenzene-1,4-diamine
InChI:
InChI=1S/C7H10N2/c1-5-4-6(8)2-3-7(5)9/h2-4H,8-9H2,1H3
InChI Key:
OBCSAIDCZQSFQH-UHFFFAOYSA-N
SMILES:
Nc1ccc(c(c1)C)N
EC Number:
202-442-1
UNII:
24JO8Z0RJU
Properties
Complexity:
92.9  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
122.084g/mol
Formal Charge:
0
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
122.171g/mol
Monoisotopic Mass:
122.084g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
52A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.6  
Literature
Title Journal
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p-Phenylenediamine and other hair dye sensitizers in Spain. Contact dermatitis 20120101
Patch testing with hydroxyethyl-p-phenylenediamine sulfate - cross-reactivity with p-phenylenediamine. Contact dermatitis 20110801
Dyeing behaviours of amino heterocyclic compounds as blue oxidative hair dye precursors applied to keratin fibres. International journal of cosmetic science 20110401
Internal exposure of hairdressers to permanent hair dyes: a biomonitoring study using urinary aromatic diamines as biomarkers of exposure. International archives of occupational and environmental health 20110301
Determination of 2,5-toluylenediamine (2,5-TDA) and aromatic amines in urine after personal application of hair dyes: kinetics and doses. Archives of toxicology 20110201
The hair dyes PPD and PTD fail to induce a T(H)2 immune response following repeated topical application in BALB/c mice. Journal of immunotoxicology 20110101
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Biological transformation pathways of 2,4-dinitro anisole and N-methyl paranitro aniline in anaerobic fluidized-bed bioreactors. Chemosphere 20101101
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Severe inflammatory and keloidal, allergic reaction due to para-phenylenediamine in temporary tattoos. Indian journal of dermatology, venereology and leprology 20100101
Metabolite screening of aromatic amine hair dyes using in vitro hepatic models. Xenobiotica; the fate of foreign compounds in biological systems 20091101
Potent skin sensitizers in oxidative hair dye products on the Swedish market. Contact dermatitis 20091101
Occupational health risks of barbers and coiffeurs in Izmir. Indian journal of occupational and environmental medicine 20090801
Hairdye-induced hepatitis: an unusal cause of acute hepatitis. Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20090401
Cross-reactions among hair dye allergens. Cutaneous and ocular toxicology 20090101
[Results of patch test in hairdressers examined in the institute of occupational medicine in Łódź]. Medycyna pracy 20090101
Reactivity of in vitro activated human T lymphocytes to p-phenylenediamine and related substances. Contact dermatitis 20081001
Primary sensitization to toluene-2,5-diamine giving rise to early positive patch reaction to p-phenylenediamine and late to toluene-2,5-diamine. Contact dermatitis 20080901
[Determination of 22 components in hair dyes by high performance liquid chromatography]. Se pu = Chinese journal of chromatography 20080901
A clinical assessment of a patch test kit marketed to U.K. hairdressers for detecting hair dye allergy. The British journal of dermatology 20071101
The reaction mechanism of p-toluenediamine anodic oxidation: an in situ ESR-UV/Vis/NIR spectroelectrochemical study. Chemphyschem : a European journal of chemical physics and physical chemistry 20071008
Toluene-2,5-diamine may be an isolated allergy in individuals sensitized by permanent hair dye. Contact dermatitis 20070901
Allergic contact dermatitis from toluene-2,5-diamine in a cream dye for eyelashes and eyebrows--quantitative exposure assessment. Contact dermatitis 20070901
Permeability of hair dye compounds p-phenylenediamine, toluene-2,5-diaminesulfate and resorcinol through protective gloves in hairdressing. The Annals of occupational hygiene 20070701
[The expanding role of occupational and non-occupational allergy to paraphenylenediamine]. Medycyna pracy 20070101
Unconsumed precursors and couplers after formation of oxidative hair dyes. Contact dermatitis 20060801
Different results of the Salmonella umu test between three isomers of phenylenediamine (PDA) derivatives. Drug and chemical toxicology 20060101
Occupational dermal exposure to permanent hair dyes among hairdressers. The Annals of occupational hygiene 20050801
Patch test reactions to cosmetic allergens in 1995-1997 and 2000-2002 in Finland--a multicentre study. Contact dermatitis 20050701
Hair dye contact allergy: quantitative exposure assessment of selected products and clinical cases. Contact dermatitis 20040601
Characterization of the sensitizing potential of chemicals by in vitro analysis of dendritic cell activation and skin penetration. The Journal of investigative dermatology 20040501
Thiol antioxidants block the activation of antigen-presenting cells by contact sensitizers. The Journal of investigative dermatology 20031101
Contact allergy to ingredients of hair cosmetics in female hairdressers and clients--an 8-year analysis of IVDK data. Contact dermatitis 20031101
Hair dye-sensitized hairdressers: the cross-reaction pattern with new generation hair dyes. Contact dermatitis 20020601
Comparative investigation of multiple organs of mice and rats in the comet assay. Mutation research 20020527
The spectrum of allergic (cross-)sensitivity in clinical patch testing with 'para amino' compounds. Allergy 20020401
Is benzoquinone the prohapten in cross-sensitivity among aminobenzene compounds? Contact dermatitis 19981201
Interaction with the aromatic hydrocarbon receptor, CYP1A induction, and mutagenicity of a series of diaminotoluenes: implications for their carcinogenicity. Toxicology and applied pharmacology 19960701
Properties