Name: Name:4-[[2-[[(1R,2R)-2-Hydroxycyclohexyl]amino]-6-benzothiazolyl]oxy]-N-methyl-2-pyridinecarboxamide
Brand: Angene
SKU: AG00368U
Rating: 90 (10 reviews)

4-[[2-[[(1R,2R)-2-Hydroxycyclohexyl]amino]-6-benzothiazolyl]oxy]-N-methyl-2-pyridinecarboxamide

CAS No.:

953769-46-5

Catalog Number:

AG00368U

Molecular Formula:

C20H22N4O3S

Molecular Weight:

398.4787

Pack Size

Purity

Availability

Location

Price(USD)

Quantity

1mg

≥98%

1 week

United States

$180

- +

5mg

99%

1 week

United States

$182

- +

10mg

99%

1 week

United States

$251

- +

50mg

99%

1 week

United States

$446

- +

100mg

99%

1 week

United States

$723

- +

Product Description

Catalog Number:

AG00368U

Chemical Name:

4-[[2-[[(1R,2R)-2-Hydroxycyclohexyl]amino]-6-benzothiazolyl]oxy]-N-methyl-2-pyridinecarboxamide

CAS Number:

953769-46-5

Molecular Formula:

C20H22N4O3S

Molecular Weight:

398.4787

MDL Number:

MFCD28142668

IUPAC Name:

4-[[2-[[(1R,2R)-2-hydroxycyclohexyl]amino]-1,3-benzothiazol-6-yl]oxy]-N-methylpyridine-2-carboxamide

InChI:

InChI=1S/C20H22N4O3S/c1-21-19(26)16-10-13(8-9-22-16)27-12-6-7-15-18(11-12)28-20(24-15)23-14-4-2-3-5-17(14)25/h6-11,14,17,25H,2-5H2,1H3,(H,21,26)(H,23,24)/t14-,17-/m1/s1

InChI Key:

ADZBMFGQQWPHMJ-RHSMWYFYSA-N

SMILES:

CNC(=O)c1nccc(c1)Oc1ccc2c(c1)sc(n2)N[C@@H]1CCCC[C@H]1O

UNII:

7W3V82OQ0P

Properties

Complexity:

540

Compound Is Canonicalized:

Yes

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Defined Bond Stereocenter Count:

Exact Mass:

398.141g/mol

Formal Charge:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Isotope Atom Count:

Molecular Weight:

398.481g/mol

Monoisotopic Mass:

398.141g/mol

Rotatable Bond Count:

Topological Polar Surface Area:

125A^2

Undefined Atom Stereocenter Count:

Undefined Bond Stereocenter Count:

XLogP3:

3.4

Literature

Title	Journal
Phenotypic and metabolic investigation of a CSF-1R kinase receptor inhibitor (BLZ945) and its pharmacologically active metabolite.	Xenobiotica; the fate of foreign compounds in biological systems 20150201
CSF1R inhibition delays cervical and mammary tumor growth in murine models by attenuating the turnover of tumor-associated macrophages and enhancing infiltration by CD8(+) T cells.	Oncoimmunology 20131201
Investigation of correlation among safety biomarkers in serum, histopathological examination, and toxicogenomics.	International journal of toxicology 20110501

Properties