Home Other Building Blocks 4H-1,2,4-Triazol-3-amine

4H-1,2,4-Triazol-3-amine

CAS No.:
61-82-5
Catalog Number:
AG00367J
Molecular Formula:
C2H4N4
Molecular Weight:
84.0800
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
25g
95%
In Stock USA
United States
$13
- +
250g
98%(HPLC)
In Stock USA
United States
$86
- +
Product Description
Catalog Number:
AG00367J
Chemical Name:
4H-1,2,4-Triazol-3-amine
CAS Number:
61-82-5
Molecular Formula:
C2H4N4
Molecular Weight:
84.0800
MDL Number:
MFCD00005230
IUPAC Name:
1H-1,2,4-triazol-5-amine
InChI:
InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)
InChI Key:
KLSJWNVTNUYHDU-UHFFFAOYSA-N
SMILES:
Nn1ccnn1
UNII:
ZF80H5GXUF
RTECS Number:
XZ3850000
Properties
Complexity:
44.8  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
84.044g/mol
Formal Charge:
0
Heavy Atom Count:
6  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
84.082g/mol
Monoisotopic Mass:
84.044g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
67.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.4  
Literature
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Hydrogen peroxide stimulates activity and alters behavior in Drosophila melanogaster. PloS one 20090101
Edgetic perturbation models of human inherited disorders. Molecular systems biology 20090101
Mutations in the human naked cuticle homolog NKD1 found in colorectal cancer alter Wnt/Dvl/beta-catenin signaling. PloS one 20090101
Staphylococcal catalase regulates its virulence and induces arthritis in catalase deficient mice. Indian journal of physiology and pharmacology 20090101
N-[(E)-(5-Methyl-thio-phen-2-yl)methyl-idene]-1H-1,2,4-triazol-3-amine. Acta crystallographica. Section E, Structure reports online 20090101
N-[(Z)-(1-Methyl-1H-pyrrol-2-yl)methyl-idene]-1H-1,2,4-triazol-5-amine. Acta crystallographica. Section E, Structure reports online 20090101
Neurospora crassa mat A-2 and mat A-3 proteins weakly interact in the yeast two-hybrid system and affect yeast growth. Genetics and molecular biology 20090101
Transcriptional modulation of ethylene response factor protein JERF3 in the oxidative stress response enhances tolerance of tobacco seedlings to salt, drought, and freezing. Plant physiology 20081201
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry 20081113
Reduction in the anxiolytic effects of ethanol by centrally formed acetaldehyde: the role of catalase inhibitors and acetaldehyde-sequestering agents. Psychopharmacology 20081101
Photosynthetic electron flow affects H2O2 signaling by inactivation of catalase in Chlamydomonas reinhardtii. Planta 20081101
The RACK1 signal anchor protein from Trypanosoma brucei associates with eukaryotic elongation factor 1A: a role for translational control in cytokinesis. Molecular microbiology 20081101
Dihydrocapsaicin (DHC), a saturated structural analog of capsaicin, induces autophagy in human cancer cells in a catalase-regulated manner. Autophagy 20081101
Modulation of reactive oxygen species by antioxidants in chronic myeloid leukemia cells enhances imatinib sensitivity through survivin downregulation. Anti-cancer drugs 20081101
Identification and functional characterization of an N-terminal oligomerization domain for polycystin-2. The Journal of biological chemistry 20081017
Progeric effects of catalase inactivation in human cells. Toxicology and applied pharmacology 20081001
Hydrogen peroxide potentiates the EDHF phenomenon by promoting endothelial Ca2+ mobilization. Arteriosclerosis, thrombosis, and vascular biology 20081001
Promoter of a cotton fibre MYB gene functional in trichomes of Arabidopsis and glandular trichomes of tobacco. Journal of experimental botany 20081001
Ethanol injected into the hypothalamic arcuate nucleus induces behavioral stimulation in rats: an effect prevented by catalase inhibition and naltrexone. Behavioural pharmacology 20081001
Ethylene- and pathogen-inducible Arabidopsis acyl-CoA-binding protein 4 interacts with an ethylene-responsive element binding protein. Journal of experimental botany 20081001
Hypothyroidism is associated with increased myostatin expression in rats. Journal of endocrinological investigation 20080901
Cadmium generates reactive oxygen- and carbon-centered radical species in rats: insights from in vivo spin-trapping studies. Free radical biology & medicine 20080815
Int6/eIF3e promotes general translation and Atf1 abundance to modulate Sty1 MAPK-dependent stress response in fission yeast. The Journal of biological chemistry 20080808
Hydrogen peroxide mediates the radiation-induced mutator phenotype in mammalian cells. The Biochemical journal 20080701
Oxidative alterations induced by D-aspartic acid in prepubertal rat testis in vitro: a mechanistic study. Theriogenology 20080701
Prostaglandins inhibit cytochrome P450 4A activity and contribute to endotoxin-induced hypotension in rats via nitric oxide production. Archives of pharmacal research 20080701
ROS-independent preconditioning in neurons via activation of mitoK(ATP) channels by BMS-191095. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20080601
Application of matrix solid-phase dispersion to the determination of amitrole and urazole residues in apples by capillary electrophoresis with electrochemical detection. Analytical and bioanalytical chemistry 20080601
Inhibition of catalase by aminotriazole in vivo results in reduction of glucose-6-phosphate dehydrogenase activity in Saccharomyces cerevisiae cells. Biochemistry. Biokhimiia 20080401
Involvement of brain catalase activity in the acquisition of ethanol-induced conditioned place preference. Physiology & behavior 20080318
Imbalance between ROS production and elimination results in apoptosis induction in primary smooth chorion trophoblast cells prepared from human fetal membrane tissues. Life sciences 20080312
Molecular characterization of vibrio cholerae DeltarelA DeltaspoT double mutants. Archives of microbiology 20080301
Neuroprotective effect of hydrogen peroxide on an in vitro model of brain ischaemia. British journal of pharmacology 20080301
Cycloheximide and disulfoton are positive in the photoclastogencity assay but do not absorb UV irradiation: another example of pseudophotoclastogenicity? Mutagenesis 20080301
Quantification of pentafluorobenzyl oxime derivatives of long chain aldehydes by GC-MS analysis. Lipids 20080301
A SAP30 complex inhibits IFN-beta expression in Rift Valley fever virus infected cells. PLoS pathogens 20080101
A novel mutant of the Sup35 protein of Saccharomyces cerevisiae defective in translation termination and in GTPase activity still supports cell viability. BMC molecular biology 20080101
The redox-sensitive transcription factor Rap2.4a controls nuclear expression of 2-Cys peroxiredoxin A and other chloroplast antioxidant enzymes. BMC plant biology 20080101
A polyadenylation factor subunit implicated in regulating oxidative signaling in Arabidopsis thaliana. PloS one 20080101
A three component one-pot procedure for the synthesis of [1,2,4]triazolo/benzimidazolo-quinazolinone derivatives in the presence of H6P2W18O(62).18H2O as a green and reusable catalyst. Molecular diversity 20080101
The cell signaling adaptor protein EPS-8 is essential for C. elegans epidermal elongation and interacts with the ankyrin repeat protein VAB-19. PloS one 20080101
Chemical-genetic profile analysis in yeast suggests that a previously uncharacterized open reading frame, YBR261C, affects protein synthesis. BMC genomics 20080101
Co-expression of GroEL/ES enhances the expression of plant catalase in bacterial cytosol. Protein and peptide letters 20080101
Acute antihypertensive action of Tempol in the spontaneously hypertensive rat. American journal of physiology. Heart and circulatory physiology 20071201
Effects of H2O2 under low- and high-aeration-level conditions on growth and catalase activity in Exiguobacterium oxidotolerans T-2-2T. Journal of bioscience and bioengineering 20071201
Catalase mediates acetaldehyde formation in the striatum of free-moving rats. Neurotoxicology 20071101
Reactive oxygen species generation by the ethylene-bis-dithiocarbamate (EBDC) fungicide mancozeb and its contribution to neuronal toxicity in mesencephalic cells. Neurotoxicology 20071101
The cytochrome p450 inhibitor ketoconazole potentiates 5-hydroxytryptamine-induced contraction in rat aorta. The Journal of pharmacology and experimental therapeutics 20071101
Mechanism of the cytotoxicity of the diazoparaquinone antitumor antibiotic kinamycin F. Free radical biology & medicine 20071015
Induction of hsp70, alterations in oxidative stress markers and apoptosis against dichlorvos exposure in transgenic Drosophila melanogaster: modulation by reactive oxygen species. Biochimica et biophysica acta 20070901
Three gene products govern (p)ppGpp production by Streptococcus mutans. Molecular microbiology 20070901
Cloning and characterization of monofunctional catalase from photosynthetic bacterium Rhodospirillum rubrum S1. Journal of microbiology and biotechnology 20070901
Contributions of pro-oxidant and anti-oxidant conditions to the actions of 24,25-dihydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 on phosphate uptake in intestinal cells. Journal of cellular biochemistry 20070801
Waterborne amitrole affects the predator-prey relationship between common frog tadpoles (Rana temporaria) and larval spotted salamander (Salamandra salamandra). Archives of environmental contamination and toxicology 20070801
Antioxidant enzyme inhibitors enhance peroxynitrite-induced cell death in U937 cells. Molecular and cellular biochemistry 20070701
Endogenous hydrogen peroxide in paraventricular nucleus mediating cardiac sympathetic afferent reflex and regulating sympathetic activity. Pflugers Archiv : European journal of physiology 20070701
Effects of 3-amino-1,2,4-triazole on the inhibition of copper corrosion in acidic chloride solutions. Journal of colloid and interface science 20070701
Selenium deficiency alters epithelial cell morphology and responses to influenza. Free radical biology & medicine 20070615
Corrosion of copper in aerated synthetic sea water solutions and its inhibition by 3-amino-1,2,4-triazole. Journal of colloid and interface science 20070515
Relationship between glutathione S-transferase, catalase, oxygen consumption, lipid peroxidation and oxidative stress in eggs and larvae of Boophilus microplus (Acarina: Ixodidae). Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20070401
Discovering new inhibitors of bacterial glucosamine-6P synthase (GlmS) by docking simulations. Bioorganic & medicinal chemistry letters 20070401
Inhibiting catalase activity sensitizes 36B10 rat glioma cells to oxidative stress. Free radical biology & medicine 20070315
Mechanism of the sulfurisation of phosphines and phosphites using 3-amino-1,2,4-dithiazole-5-thione (xanthane hydride). Organic & biomolecular chemistry 20070207
Evaluation of oxidative stress in D-serine induced nephrotoxicity. Toxicology 20070105
Oxidative stress impairs heme detoxification in the midgut of the cattle tick, Rhipicephalus (Boophilus) microplus. Molecular and biochemical parasitology 20070101
Evolution of a novel subfamily of nuclear receptors with members that each contain two DNA binding domains. BMC evolutionary biology 20070101
2-Arylhydrazononitriles as building blocks in heterocyclic synthesis: A novel route to 2-substituted-1,2,3-triazoles and 1,2,3-triazolo[4,5-b]pyridines. Beilstein journal of organic chemistry 20070101
E2F8 is a nonreceptor activator of heterotrimeric G proteins. Journal of molecular signaling 20070101
Histamine release and fibrinogen adsorption mediate acute inflammatory responses to biomaterial implants in humans. Journal of translational medicine 20070101
Ethanol oxidation in the living brain. Alcohol and alcoholism (Oxford, Oxfordshire) 20070101
Critical role of exposure time to endogenous oxidative stress in hepatocyte apoptosis. Redox report : communications in free radical research 20070101
MADS-complexes regulate transcriptome dynamics during pollen maturation. Genome biology 20070101
Acute administration of 3-nitropropionic acid, a reactive oxygen species generator, boosts ethanol-induced locomotor stimulation. New support for the role of brain catalase in the behavioural effects of ethanol. Neuropharmacology 20061201
Parthenolide-induced apoptosis in multiple myeloma cells involves reactive oxygen species generation and cell sensitivity depends on catalase activity. Apoptosis : an international journal on programmed cell death 20061201
Gamma-irradiation-induced intercellular adhesion molecule-1 (ICAM-1) expression is associated with catalase: activation of Ap-1 and JNK. Journal of toxicology and environmental health. Part A 20061201
Drosophila SPF45: a bifunctional protein with roles in both splicing and DNA repair. PLoS genetics 20061201
Synthesis of tetrahydrobenzimidazo[1,2-b]quinazolin-1(2H)-one and tetrahydro-1,2,4-triazolo[5,1-b]quinazolin-8(4H)-one ring systems under solvent-free conditions. Combinatorial chemistry & high throughput screening 20061201
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. Journal of molecular graphics & modelling 20061101
Mechanism of ascorbic acid-induced reversion against malignant phenotype in human gastric cancer cells. Biomedical and environmental sciences : BES 20061001
Antioxidant enzyme inhibitors enhance nitric oxide-induced cell death in U937 cells. Biochimie 20060701
Effect of organic additives on the mitigation of volatility of 1-nitro-3,3'-dinitroazetidine (TNAZ): next generation powerful melt cast able high energy material. Journal of hazardous materials 20060630
Indomethacin induces small intestinal damage and inhibits amitrole-associated thyroid carcinogenesis in rats initiated with N-bis(2-hydroxypropyl)nitrosamine. Toxicology letters 20060620
Hyperbaric oxygen preconditioning induces tolerance against spinal cord ischemia by upregulation of antioxidant enzymes in rabbits. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20060501
Endothelial mediators of the acetylcholine-induced relaxation of the rat femoral artery. Vascular pharmacology 20060501
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Nitric oxide protects macrophages from hydrogen peroxide-induced apoptosis by inducing the formation of catalase. Journal of immunology (Baltimore, Md. : 1950) 20060415
H2O2 injury in beta thalassemic erythrocytes: protective role of catalase and the prooxidant effects of GSH. Free radical biology & medicine 20060401
Characterization of monofunctional catalase KatA from radioresistant bacterium Deinococcus radiodurans. Journal of bioscience and bioengineering 20060401
Purification and characterization of a catalase from photosynthetic bacterium Rhodospirillum rubrum S1 grown under anaerobic conditions. Journal of microbiology (Seoul, Korea) 20060401
Involvement of endonuclease G in nucleosomal DNA fragmentation under sustained endogenous oxidative stress. The Journal of biological chemistry 20060310
Ebs1p, a negative regulator of gene expression controlled by the Upf proteins in the yeast Saccharomyces cerevisiae. Eukaryotic cell 20060201
Studies on the goitrogenic mechanism of action of N,N,N',N'-tetramethylthiourea. Toxicology 20060116
Eliminating gene conversion improves high-throughput genetics in Saccharomyces cerevisiae. Genetics 20060101
Analysis of amitrole by normal-phase liquid chromatography and tandem mass spectrometry using a sheath liquid electrospray interface. Rapid communications in mass spectrometry : RCM 20060101
Isolation of plant transcription factors using a modified yeast one-hybrid system. Plant methods 20060101
Flexible promoter architecture requirements for coactivator recruitment. BMC molecular biology 20060101
Manganese superoxide dismutase protects from TNF-alpha-induced apoptosis by increasing the steady-state production of H2O2. Antioxidants & redox signaling 20060101
Acyl-CoA oxidase activity from Beauveria bassiana, an entomopathogenic fungus. Journal of basic microbiology 20060101
Clues on the role of Beauveria bassiana catalases in alkane degradation events. Mycologia 20060101
Determination of amitrole and urazole in water samples by capillary zone electrophoresis using simultaneous UV and amperometrical detection. Journal of chromatography. A 20051216
Peroxisomal proliferation protects from beta-amyloid neurodegeneration. The Journal of biological chemistry 20051209
Hemoglobin autoxidation and regulation of endogenous H2O2 levels in erythrocytes. Free radical biology & medicine 20051201
Ability of the Hershberger assay protocol to detect thyroid function modulators. Archives of toxicology 20051101
Adaptive response of antioxidant enzymes to catalase inhibition by aminotriazole in goldfish liver and kidney. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20051101
Temperature- or guest-induced drastic single-crystal-to-single-crystal transformations of a nanoporous coordination polymer. Journal of the American Chemical Society 20051019
Nonosmotic release of vasopressin and renal aquaporins in impaired urinary dilution in hypothyroidism. American journal of physiology. Renal physiology 20051001
Protective role of hydrogen peroxide in oxygen-deprived dopaminergic neurones of the rat substantia nigra. The Journal of physiology 20051001
Global role of the protein kinase Gcn2 in the human pathogen Candida albicans. Eukaryotic cell 20051001
Brain catalase mediates potentiation of social recognition memory produced by ethanol in mice. Drug and alcohol dependence 20050901
Signaling of the Human P2Y(1) Receptor Measured by a Yeast Growth Assay with Comparisons to Assays of Phospholipase C and Calcium Mobilization in 1321N1 Human Astrocytoma Cells. Purinergic signalling 20050901
Pyrimidine acyclo-C-nucleosides by ring transformations of 2-formyl-L-arabinal. Molecules (Basel, Switzerland) 20050831
Catalase inhibition by amino triazole induces oxidative stress in goldfish brain. Brain research 20050809
Convenient synthesis of fused heterocyclic 1,3,5-triazines from some N-acyl imidates and heterocyclic amines as anticancer and antioxidant agents. Archiv der Pharmazie 20050801
NGF rescues DRG neurons in vitro from oxidative damage produced by hemodialyzers. Neurotoxicology 20050601
Prediction of genotoxicity of chemical compounds by statistical learning methods. Chemical research in toxicology 20050601
Endogenous hydrogen peroxide regulates the excitability of midbrain dopamine neurons via ATP-sensitive potassium channels. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050427
C-reactive protein does not relax vascular smooth muscle: effects mediated by sodium azide in commercially available preparations. American journal of physiology. Heart and circulatory physiology 20050401
Formation of refractory ring-expanded triazine intermediates during the photocatalyzed mineralization of the endocrine disruptor amitrole and related triazole derivatives at UV-irradiated TiO2/H2O interfaces. Environmental science & technology 20050401
Hydrogen peroxide-induced cell death in Arabidopsis: transcriptional and mutant analysis reveals a role of an oxoglutarate-dependent dioxygenase gene in the cell death process. IUBMB life 20050301
Regional heterogeneity for the intracranial self-administration of ethanol and acetaldehyde within the ventral tegmental area of alcohol-preferring (P) rats: involvement of dopamine and serotonin. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050201
Primary hepatocyte apoptosis is unlikely to relate to caspase-3 activity under sustained endogenous oxidative stress. Free radical research 20050201
Lack of combination hepatocarcinogenicity of harman, norharman and amitrole when given with NaNO2 in the rat. The Journal of toxicological sciences 20050201
The effects of reactive oxygen species on amphibian aging. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20050201
Tamoxifen up-regulates catalase production, inhibits vessel wall neutrophil infiltration, and attenuates development of experimental abdominal aortic aneurysms. Journal of vascular surgery 20050101
Purification and characterization of a monofunctional catalase from an alkaliphilic Bacillus sp. F26. Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20050101
Very-long-chain fatty acids activate lysosomal hydrolases in neonatal human skin tissue. Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20050101
Brain catalase activity inhibition as well as opioid receptor antagonism increases ethanol-induced HPA axis activation. Alcoholism, clinical and experimental research 20041201
Antioxidants and ocular cell type differences in cytoprotection from formic acid toxicity in vitro. Toxicological sciences : an official journal of the Society of Toxicology 20041101
Impact of ethanol and acetaldehyde on DNA and cell viability of cultured neurones. Cell biology and toxicology 20041101
The glial antioxidant network and neuronal ascorbate: protective yet permissive for H(2)O(2) signaling. Neuron glia biology 20041101
Role of glutathione in the adaptive tolerance to H2O2. Free radical biology & medicine 20041015
Simultaneous separation and on-line concentration of amitrole and benzimidazole pesticides by capillary electrophoresis with a volatile migration buffer applicable to mass spectrometric detection. Journal of chromatography. A 20041008
Dietary selenium supplementation prolongs pentobarbital induced hypnosis. The Journal of nutritional biochemistry 20040901
Important role of striatal catalase in aging- and reserpine-induced oral dyskinesia. Neuropharmacology 20040801
Catalase-independent early-gene expression in rat brain following acute ethanol exposure. Brain research 20040730
Endogenous glutathione and catalase protect cultured rat astrocytes from the iron-mediated toxicity of hydrogen peroxide. Neuroscience letters 20040708
High levels of catalase and glutathione peroxidase activity dampen H2O2 signaling in human alveolar macrophages. American journal of respiratory cell and molecular biology 20040701
Influence of vitamin E, sodium selenite, and astrocyte-conditioned medium on neuronal survival after chronic exposure to ethanol. Alcohol (Fayetteville, N.Y.) 20040601
Endogenously generated hydrogen peroxide is required for execution of melphalan-induced apoptosis as well as oxidation and externalization of phosphatidylserine. Chemical research in toxicology 20040501
Exceptionally stable, hollow tubular metal-organic architectures: synthesis, characterization, and solid-state transformation study. Journal of the American Chemical Society 20040324
An endogenous metabolite of dopamine, 3,4-dihydroxyphenylethanol, acts as a unique cytoprotective agent against oxidative stress-induced injury. Free radical biology & medicine 20040301
Ethanol but not acetaldehyde induced changes in brain taurine: a microdialysis study. Amino acids 20040301
Thylakoid dismantling of damaged unfunctional chloroplasts modulates the Cab and RbcS gene expression in wheat leaves. Journal of photochemistry and photobiology. B, Biology 20040220
Influence of polyethylene-glycol-superoxide dismutase and combined depletion and repletion of antioxidants on nitrergic relaxation in the pig gastric fundus. European journal of pharmacology 20040220
Glycerol-insensitive Arabidopsis mutants: gli1 seedlings lack glycerol kinase, accumulate glycerol and are more resistant to abiotic stress. The Plant journal : for cell and molecular biology 20040201
Synthesis, structure and properties of N-acetylated derivatives of methyl 5-amino-1H-[1,2,4]triazole-3-carboxylate. Chemical & pharmaceutical bulletin 20040201
Transcriptional regulation of CYP2B1 induction in primary rat hepatocyte cultures: repression by epidermal growth factor is mediated via a distal enhancer region. Molecular pharmacology 20040101
Antioxidant capacity of cultured mammalian cells estimated by ESR method. TheScientificWorldJournal 20040101
Concentration of TBA-reactive substances in type II pneumocytes exposed to oxidative stress. Archivum immunologiae et therapiae experimentalis 20040101
Catalase has negligible inhibitory effects on endothelium-dependent relaxations in mouse isolated aorta and small mesenteric artery. British journal of pharmacology 20031201
Role of glutathione redox cycle and catalase in defense against oxidative stress induced by endosulfan in adrenocortical cells of rainbow trout (Oncorhynchus mykiss). Toxicology and applied pharmacology 20031015
Expression of senescence-enhanced genes in response to oxidative stress. Journal of experimental botany 20031001
Purification, characterization, and physiological response of a catalase-peroxidase in Mycobacterium sp. strain JC1 DSM 3803 grown on methanol. FEMS microbiology letters 20030926
Involvement of brain ethanol metabolism on acute tolerance development and on ethanol consumption in alcohol-drinker (UChB) and non-drinker (UChA) rats. Addiction biology 20030901
Enhancement of catalase activity by repetitive low-grade H2O2 exposures protects fibroblasts from subsequent stress-induced apoptosis. Mutation research 20030828
Resistance to tumor necrosis factor-alpha (TNF-alpha)-induced apoptosis in rat hepatoma cells expressing TNF-alpha is linked to low antioxidant enzyme expression. The Journal of biological chemistry 20030808
Hexose monophosphate shunt activities in human erythrocytes during oxidative damage induced by hydrogen peroxide. Archives of toxicology 20030701
The pattern of systemic acquired resistance induction within the Arabidopsis rosette in relation to the pattern of translocation. Plant physiology 20030601
Role of catalase in ethanol-induced conditioned taste aversion: a study with 3-amino-1,2,4-triazole. Drug and alcohol dependence 20030501
Endothelium dysfunction in LDL receptor knockout mice: a role for H2O2. British journal of pharmacology 20030401
Ceramide increases oxidative damage due to inhibition of catalase by caspase-3-dependent proteolysis in HL-60 cell apoptosis. The Journal of biological chemistry 20030314
A highly efficient and sensitive screening method for trans-activation activity of estrogen receptors. Gene 20030313
Adsorption of pesticides on resins. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20030301
The role of oxidative stress in the in vitro induction of micronuclei by pesticides in mouse lung fibroblasts. Mutagenesis 20030301
Effect of catalase-specific inhibitor 3-amino-1,2,4-triazole on yeast peroxisomal catalase in vivo. FEMS microbiology letters 20030214
Cloning and characterization of katA, encoding the major monofunctional catalase from Xanthomonas campestris pv. phaseoli and characterization of the encoded catalase KatA. Current microbiology 20030201
Inhibition of oral cancer cell growth by adenovirusMnSOD plus BCNU treatment. Free radical biology & medicine 20030201
Determination of 3-amino-1,2,4-triazole (amitrole) in environmental waters by capillary electrophoresis. Talanta 20030102
Essential requirements for substrate binding affinity and selectivity toward human CYP2 family enzymes. Archives of biochemistry and biophysics 20030101
Short-term depletion of catalase suppresses cadmium-elicited c-Jun N-terminal kinase activation and apoptosis: role of protein phosphatases. Carcinogenesis 20030101
Viable nonsense mutants for the essential gene SUP45 of Saccharomyces cerevisiae. BMC molecular biology 20030101
Purification and characterization of a novel thermo-alkali-stable catalase from Thermus brockianus. Biotechnology progress 20030101
[Effect of azole derivatives on lucigenin-dependent microsome chemiluminescence]. Biomeditsinskaia khimiia 20030101
[Effect of aminotriazole on the activity of catalase and glucose-6-phosphate dehydrogenase in tissues of two frog species--Rana ridibunda and Rana esculenta]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20030101
Oxidative stress response of rat testis to model prooxidants in vitro and its modulation. Toxicology in vitro : an international journal published in association with BIBRA 20021201
Adenoviral-mediated overexpression of catalase inhibits endothelial cell proliferation. American journal of physiology. Heart and circulatory physiology 20021201
Age- and hypertension-induced changes in abnormal contractions in rat aorta. Journal of cardiovascular pharmacology 20021201
Ethanol-stimulated behaviour in mice is modulated by brain catalase activity and H2O2 rate of production. Psychopharmacology 20021201
Control of demand-driven biosynthesis of glutathione in green Arabidopsis suspension culture cells. Plant physiology 20021201
Characterization of urinary volatiles in Swiss male mice (Mus musculus): bioassay of identified compounds. Journal of biosciences 20021201
Characterization of nitric oxide consumption pathways by normal, chronic granulomatous disease and myeloperoxidase-deficient human neutrophils. Journal of immunology (Baltimore, Md. : 1950) 20021115
The as-1 promoter element is an oxidative stress-responsive element and salicylic acid activates it via oxidative species. Plant physiology 20021101
Ascorbic acid induces redifferentiation and growth inhibition in human hepatoma cells by increasing endogenous hydrogen peroxide. Die Pharmazie 20021101
Thyroid status regulates CART but not AgRP mRNA levels in the rat hypothalamus. Neuroreport 20021007
Bleaching herbicide effects on plastids of dark-grown plants: lipid composition of etioplasts in amitrole and norflurazon-treated barley leaves. Journal of experimental botany 20020901
Enhancement of glutathione-dependent haemin degradation by ascorbic acid. Biochemical pharmacology 20020815
Brain catalase inhibition blocks ethanol-related decrease of blood luteinizing hormone levels in mice. Alcoholism, clinical and experimental research 20020801
Unsymmetrical 1,1'-disubstituted ferrocenes: synthesis of Co(ii), Cu(ii), Ni(ii) and Zn(ii) chelates of ferrocenyl -1-thiadiazolo-1'-tetrazole, -1-thiadiazolo-1'-triazole and -1-tetrazolo-1'-triazole with antimicrobial properties. Journal of enzyme inhibition and medicinal chemistry 20020801
Control of ceramide-induced apoptosis by IGF-1: involvement of PI-3 kinase, caspase-3 and catalase. Cell death and differentiation 20020601
Role of acetaldehyde in the discriminative stimulus effects of ethanol. Alcoholism, clinical and experimental research 20020601
Purification, characterization, and gene sequencing of a catalase from an alkali- and halo-tolerant bacterium, Halomonas sp. SK1. Bioscience, biotechnology, and biochemistry 20020501
Role of endogenous reactive oxygen derived species and cyclooxygenase mediators in 5-hydroxytryptamine-induced contractions in rat aorta: relationship to nitric oxide. Pharmacological research 20020501
Catalase-dependent measurement of H2O2 in intact mitochondria. Mitochondrion 20020501
Hydrogen peroxide protects tobacco from oxidative stress by inducing a set of antioxidant enzymes. Cellular and molecular life sciences : CMLS 20020401
Acetylation of 5-amino-1H-[1,2,4]triazole revisited. Journal of agricultural and food chemistry 20020313
Cytoprotective antioxidant activity of serum albumin and autocrine catalase in chronic lymphocytic leukaemia. British journal of haematology 20020201
Role of catalase in the smooth muscle relaxant actions of sodium azide and cyanamide. European journal of pharmacology 20020118
Effect of a high salt diet on microvascular antioxidant enzymes. Journal of vascular research 20020101
Elimination of *O(2)(-)/H(2)O(2) by alpha-lipoic acid mediates the recovery of basal EDRF/NO availability and the reversal of superoxide dismutase-induced relaxation in diabetic rat aorta. Diabetes, obesity & metabolism 20020101
[Possible role of catalase in the adaptation to diving in semiaquatic rodents Ondatra zibethica]. Zhurnal evoliutsionnoi biokhimii i fiziologii 20020101
Oxidative stress-induced expression of catalases in Comamonas terrigena. Folia microbiologica 20020101
Protection against acetaminophen hepatotoxicity by clofibrate pretreatment: role of catalase induction. Journal of biochemical and molecular toxicology 20020101
Mechanism of aerobic transformation of carbon tetrachloride by poplar cells. Biodegradation 20020101
Determination of the herbicide amitrole in water with pre-column derivatization, liquid chromatography and tandem mass spectrometry. Journal of chromatography. A 20011214
Influence of brain catalase on ethanol-induced loss of righting reflex in mice. Drug and alcohol dependence 20011201
Ceramide-mediated apoptosis in lung epithelial cells is regulated by glutathione. American journal of respiratory cell and molecular biology 20011201
Molecular and kinetic study of catalase-1, a durable large catalase of Neurospora crassa. Free radical biology & medicine 20011201
Haemonchus contortus utilises catalase in defence against exogenous hydrogen peroxide in vitro. International journal for parasitology 20011201
Mitochondria enter the nucleus (one further problem in chronic alcoholism). Biochemistry. Biokhimiia 20011201
Inhibition of catalase activity with 3-amino-triazole enhances the cytotoxicity of the Alzheimer's amyloid-beta peptide. Neurotoxicology 20011201
Alteration of cadmium-induced mutational spectrum by catalase depletion in Chinese hamster ovary-K1 cells. Mutation research 20011115
Cytogenetic effects of propyl gallate in CHO-K1 cells. Mutation research 20011115
Hydrogen peroxide detoxification in the midgut of the blood-sucking insect, Rhodnius prolixus. Archives of insect biochemistry and physiology 20011001
Characterization of a catalase-peroxidase from the hyperthermophilic archaeon Archaeoglobus fulgidus. Extremophiles : life under extreme conditions 20011001
Hydrogen peroxide production in mouse tissues after acute d-amphetamine administration. Influence of monoamine oxidase inhibition. Archives of toxicology 20011001
Oxidative stress activates ATMPK6, an Arabidopsis homologue of MAP kinase. Plant & cell physiology 20010901
Adverse consequences of erythrocyte exposure to menadione: involvement of reactive oxygen species generation in plasma. Journal of toxicology and environmental health. Part A 20010824
Measurement of inhibin A: a modification to an enzyme-linked immunosorbent assay. Prenatal diagnosis 20010801
Hyperbaric oxygenation pretreatment induces catalase and reduces infarct size in ischemic rat myocardium. Pflugers Archiv : European journal of physiology 20010701
Induction of jlbA mRNA synthesis for a putative bZIP protein of Aspergillus nidulans by amino acid starvation. Current genetics 20010701
Repression of phenobarbital-dependent CYP2B1 mRNA induction by reactive oxygen species in primary rat hepatocyte cultures. Molecular pharmacology 20010601
Hydrogen peroxide removal and glutathione mixed disulfide formation during metabolic inhibition in mesencephalic cultures. Journal of neurochemistry 20010601
Hydrogen peroxide inhibits photosynthetic electron transport in cells of cyanobacteria. Biochemistry. Biokhimiia 20010601
Amitrole treatment of etiolated barley seedlings leads to deregulation of tetrapyrrole synthesis and to reduced expression of Lhc and RbcS genes. Planta 20010501
Expression and prognostic significance of catalase in malignant mesothelioma. Cancer 20010401
Prepro-orexin mRNA levels in the rat hypothalamus, and orexin receptors mRNA levels in the rat hypothalamus and adrenal gland are not influenced by the thyroid status. Neuroscience letters 20010316
Role of the epithelium in opposing H(2)O(2)-induced modulation of acetylcholine-induced contractions in rabbit intrapulmonary bronchiole. British journal of pharmacology 20010301
Taurine modulates catalase, aldehyde dehydrogenase, and ethanol elimination rates in rat brain. Alcohol and alcoholism (Oxford, Oxfordshire) 20010101
Pre- and postjunctional protective effect of neocuproine on the nitrergic neurotransmitter in the mouse gastric fundus. British journal of pharmacology 20010101
Post-transcriptional control of catalase expression in garlic-treated rats. Molecular and cellular biochemistry 20010101
[Determination of heterocyclic inhibitors of nitrification in environmental objects and biomaterials]. Gigiena i sanitariia 20010101
Acetylation of methyl 5-amino-1H-[1,2,4]triazole-3-carboxylate. Acta biochimica Polonica 20010101
Red cells from glutathione peroxidase-1-deficient mice have nearly normal defenses against exogenous peroxides. Blood 20000901
Activation of JNK, p38 and ERK mitogen-activated protein kinases by chromium(VI) is mediated through oxidative stress but does not affect cytotoxicity. Carcinogenesis 20000801
Angiotensin II stimulates endothelial vascular cell adhesion molecule-1 via nuclear factor-kappaB activation induced by intracellular oxidative stress. Arteriosclerosis, thrombosis, and vascular biology 20000301
Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide-dependent pathway. Blood 19990915
Stable overexpression of manganese superoxide dismutase in mitochondria identifies hydrogen peroxide as a major oxidant in the AP-1-mediated induction of matrix-degrading metalloprotease-1. The Journal of biological chemistry 19990903
Effect of the in vivo catalase inhibition on aminonucleoside nephrosis. Free radical biology & medicine 19990801
Involvement of hydrogen peroxide and hydroxyl radical in chemically induced apoptosis of HL-60 cells. Biochemical pharmacology 19990615
Purification, characterization, and primary structure of a monofunctional catalase from Methanosarcina barkeri. Archives of microbiology 19990401
Antihypertensive and vasodilator actions of antioxidants in spontaneously hypertensive rats. American journal of hypertension 19981201
Geometrically and conformationally restrained cinnamoyl compounds as inhibitors of HIV-1 integrase: synthesis, biological evaluation, and molecular modeling. Journal of medicinal chemistry 19981008
Differential xenobiotic induction of CYP2A5 in mouse liver, kidney, lung, and olfactory mucosa. Drug metabolism and disposition: the biological fate of chemicals 19980801
Increase of reactive oxygen species (ROS) in endothelial cells by shear flow and involvement of ROS in shear-induced c-fos expression. Journal of cellular physiology 19980501
Effect of 3-aminotriazole on anchorage independence and mutagenicity in cadmium- and lead-treated diploid human fibroblasts. Carcinogenesis 19980501
Endogenous antioxidant enzymes and glutathione S-transferase in protection of mesothelioma cells against hydrogen peroxide and epirubicin toxicity. British journal of cancer 19980401
Role of H2O2 and heme-containing O2 sensors in hypoxic regulation of tyrosine hydroxylase gene expression. The American journal of physiology 19980101
Glutathione peroxidase and catalase modulate the genotoxicity of arsenite. Toxicology 19970905
Reactive oxygen species may participate in the mutagenicity and mutational spectrum of cadmium in Chinese hamster ovary-K1 cells. Chemical research in toxicology 19961201
Identification of a novel growth-promoting factor with a wide target cell spectrum from various tumor cells as catalase. Journal of biochemistry 19961001
Dapsone-induced hemolytic anemia: role of glucose-6-phosphate dehydrogenase in the hemolytic response of rat erythrocytes to N-hydroxydapsone. The Journal of pharmacology and experimental therapeutics 19950501
Up-regulation of CYP2A5 expression by porphyrinogenic agents in mouse liver. Naunyn-Schmiedeberg's archives of pharmacology 19950401
Hepatic oxidative stress and related defenses during treatment of mice with acetylsalicylic acid and other peroxisome proliferators. Journal of biochemical toxicology 19950401
Puromycin aminonucleoside inhibits mesangial cell-induced contraction of collagen gels by stimulating production of reactive oxygen species. Kidney international 19950301
Role of hydrogen peroxide in hypoxia-induced erythropoietin production. The Biochemical journal 19941015
Reactive oxygen metabolite-induced toxicity to cultured bovine endothelial cells: status of cellular iron in mediating injury. Journal of cellular physiology 19940701
Effects of inhibition of catalase and superoxide dismutase activity on antioxidant enzyme mRNA levels. The American journal of physiology 19931201
Agent-specific ras oncogene activation in rat thyroid tumours. Oncogene 19881101
Synthesis of tetrazole ribonucleosides and their evaluation as antiviral agents. 2. 5-Amino-1-(beta-D-ribofuranosyl)-1H-tetrazole and 5-amino-2-(beta-D-ribofuranosyl)-2H-tetrazole. Journal of medicinal chemistry 19760801
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