Home Other Building Blocks Diphenyleneiodonium chloride

Diphenyleneiodonium chloride

CAS No.:
4673-26-1
Catalog Number:
AG00366I
Molecular Formula:
C12H8ClI
Molecular Weight:
314.5494
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
≥99%
1 week
United States
$105
- +
10mg
≥99%
1 week
United States
$135
- +
50mg
99%
1 week
United States
$390
- +
100mg
99%
1 week
United States
$640
- +
Product Description
Catalog Number:
AG00366I
Chemical Name:
Diphenyleneiodonium chloride
CAS Number:
4673-26-1
Molecular Formula:
C12H8ClI
Molecular Weight:
314.5494
MDL Number:
MFCD00214165
IUPAC Name:
8-iodoniatricyclo[7.4.0.02,7]trideca-1(13),2,4,6,9,11-hexaene;chloride
InChI:
InChI=1S/C12H8I.ClH/c1-3-7-11-9(5-1)10-6-2-4-8-12(10)13-11;/h1-8H;1H/q+1;/p-1
InChI Key:
FCFZKAVCDNTYID-UHFFFAOYSA-M
SMILES:
c1ccc2c(c1)[I+]c1c2cccc1.[Cl-]
UNII:
7M9D81YZ2N
Properties
Complexity:
170  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
313.936g/mol
Formal Charge:
0
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
314.55g/mol
Monoisotopic Mass:
313.936g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
0A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Broad activity of diphenyleneiodonium analogues against Mycobacterium tuberculosis, malaria parasites and bacterial pathogens. European journal of medicinal chemistry 20180325
Characterization of potent and selective iodonium-class inhibitors of NADPH oxidases. Biochemical pharmacology 20171101
Paraquat Induces Cell Death Through Impairing Mitochondrial Membrane Permeability. Molecular neurobiology 20160501
Selective Targeting of Heme Protein in Cytochrome P450 and Nitric Oxide Synthase by Diphenyleneiodonium. Toxicological sciences : an official journal of the Society of Toxicology 20160501
Iron depletion in HCT116 cells diminishes the upregulatory effect of phenethyl isothiocyanate on heme oxygenase-1. Toxicology and applied pharmacology 20160415
Enhanced NADPH oxidases and reactive oxygen species in the mechanism of methanol-initiated protein oxidation and embryopathies in vivo and in embryo culture. Archives of toxicology 20160301
Identification of a novel small-molecule agonist for human G protein-coupled receptor 3. The Journal of pharmacology and experimental therapeutics 20140601
Ethanol increases matrix metalloproteinase-12 expression via NADPH oxidase-dependent ROS production in macrophages. Toxicology and applied pharmacology 20131115
Reactive oxygen species and Wnt signalling crosstalk patterns mouse extraembryonic endoderm. Cellular signalling 20121201
Zinc induced phytotoxicity mechanism involved in root growth of Triticum aestivum L. Ecotoxicology and environmental safety 20121201
Suppression of the inflammatory response by diphenyleneiodonium after transient focal cerebral ischemia. Journal of neurochemistry 20121101
Endothelin-1 increases superoxide production in human coronary artery bypass grafts. Life sciences 20121015
NADPH oxidase-mediated upregulation of connexin43 contributes to podocyte injury. Free radical biology & medicine 20120915
Lipopolysaccharide-activated microglia lower P-glycoprotein function in brain microvascular endothelial cells. Neuroscience letters 20120822
Relationship of proton motive force and the F(0)F (1)-ATPase with bio-hydrogen production activity of Rhodobacter sphaeroides: effects of diphenylene iodonium, hydrogenase inhibitor, and its solvent dimethylsulphoxide. Journal of bioenergetics and biomembranes 20120801
Emerging roots alter epidermal cell fate through mechanical and reactive oxygen species signaling. The Plant cell 20120801
Integration of pro-inflammatory cytokines, 12-lipoxygenase and NOX-1 in pancreatic islet beta cell dysfunction. Molecular and cellular endocrinology 20120706
Inhibition of the NADPH oxidase regulates heme oxygenase 1 expression in chronic myeloid leukemia. Cancer 20120701
Interrelationship between calmodulin (CaM) and H2O2 in abscisic acid-induced antioxidant defense in the seedlings of Panax ginseng. Molecular biology reports 20120701
Lansoprazole inhibits nitric oxide and prostaglandin E(2) production in murine macrophage RAW 264.7 cells. Inflammation 20120601
Antiproliferative mechanisms of action of the flavin dehydrogenase inhibitors diphenylene iodonium and di-2-thienyliodonium based on molecular profiling of the NCI-60 human tumor cell panel. Biochemical pharmacology 20120501
NADPH oxidase is involved in H2O2-induced differentiation of human promyelocytic leukaemia HL-60 cells. Cell biology international 20120401
Distinct signalling mechanisms mediate neutrophil attraction to bacterial infection and tissue injury. Cellular microbiology 20120401
A peroxidase-dependent apoplastic oxidative burst in cultured Arabidopsis cells functions in MAMP-elicited defense. Plant physiology 20120401
NOX2-derived reactive oxygen species are crucial for CD29-induced pro-survival signalling in cardiomyocytes. Cardiovascular research 20120301
S-Adenosylhomocysteine induces apoptosis and phosphatidylserine exposure in endothelial cells independent of homocysteine. Atherosclerosis 20120301
Brown adipose tissue mitochondria oxidizing fatty acids generate high levels of reactive oxygen species irrespective of the uncoupling protein-1 activity state. Biochimica et biophysica acta 20120301
Does NAD(P)H oxidase-derived H2O2 participate in hypotonicity-induced insulin release by activating VRAC in β-cells? Pflugers Archiv : European journal of physiology 20120201
Different characteristics of reactive oxygen species production by human keratinocyte cell line cells in response to allergens and irritants. Experimental dermatology 20120201
Early signaling network in tobacco cells elicited with methyl jasmonate and cyclodextrins. Plant physiology and biochemistry : PPB 20120201
NADPH oxidase in plasma membrane is involved in stomatal closure induced by dehydroascorbate. Plant physiology and biochemistry : PPB 20120201
Protective effects of aspirin from cardiac hypertrophy and oxidative stress in cardiomyopathic hamsters. Oxidative medicine and cellular longevity 20120101
Jasmonic acid is involved in the signaling pathway for fungal endophyte-induced volatile oil accumulation of Atractylodes lancea plantlets. BMC plant biology 20120101
Oxidative mechanisms for the biotransformation of 1-methyl-1,6-dihydropyridine-2-carbaldoxime to pralidoxime chloride. Life sciences 20111219
Mechanisms regulating superoxide generation in experimental models of phenylketonuria: an essential role of NADPH oxidase. Molecular genetics and metabolism 20111101
NOX1 participates in ROS-dependent cell death of colon epithelial Caco2 cells induced by Entamoeba histolytica. Microbes and infection 20111101
Reactive oxygen species regulate M-CSF-induced monocyte/macrophage proliferation through SHP1 oxidation. Cellular signalling 20111001
Metabolic utilization of exogenous pyruvate by mutant p53 (R175H) human melanoma cells promotes survival under glucose depletion. Cancer biology & therapy 20111001
NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action. British journal of pharmacology 20110901
NADPH oxidase-dependent formation of reactive oxygen species contributes to angiotensin II-induced epithelial-mesenchymal transition in rat peritoneal mesothelial cells. International journal of molecular medicine 20110901
Activation and induction of cytosolic phospholipase A2 by TNF-α mediated through Nox2, MAPKs, NF-κB, and p300 in human tracheal smooth muscle cells. Journal of cellular physiology 20110801
Modulation of redox signaling promotes apoptosis in epithelial ovarian cancer cells. Gynecologic oncology 20110801
Cell wall damage-induced lignin biosynthesis is regulated by a reactive oxygen species- and jasmonic acid-dependent process in Arabidopsis. Plant physiology 20110701
Effect of NADPH-oxidase inhibitors in the experimental model of zymosan-induced shock in mice. Free radical research 20110701
Neuroinflammation and α-synuclein dysfunction potentiate each other, driving chronic progression of neurodegeneration in a mouse model of Parkinson's disease. Environmental health perspectives 20110601
The mitochondria mediate the induction of NOX1 gene expression by aldosterone in an ATF-1-dependent manner. Cellular & molecular biology letters 20110601
Crosstalk between reactive oxygen species and hormonal signalling pathways regulates grain dormancy in barley. Plant, cell & environment 20110601
Diphenyleneiodonium inhibits the activation of mitogen-activated protein kinases and the expression of monocyte chemoattractant protein-1 in Helicobacter pylori-infected gastric epithelial AGS cells. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20110501
NADPH oxidase inhibition attenuates total body irradiation-induced haematopoietic genomic instability. Mutagenesis 20110501
Up-regulation and sustained activation of Stat1 are essential for interferon-gamma (IFN-gamma)-induced dual oxidase 2 (Duox2) and dual oxidase A2 (DuoxA2) expression in human pancreatic cancer cell lines. The Journal of biological chemistry 20110408
High-frequency field stimulation of primary neurons enhances ryanodine receptor-mediated Ca2+ release and generates hydrogen peroxide, which jointly stimulate NF-κB activity. Antioxidants & redox signaling 20110401
Serotonin 2A and 2B receptor-induced phrenic motor facilitation: differential requirement for spinal NADPH oxidase activity. Neuroscience 20110331
Involvement of H-Ras and reactive oxygen species in proinflammatory cytokine-induced matrix metalloproteinase-13 expression in human articular chondrocytes. Archives of biochemistry and biophysics 20110315
Inhibition of NADPH oxidases prevents chronic ethanol-induced bone loss in female rats. The Journal of pharmacology and experimental therapeutics 20110301
Nox2-based NADPH oxidase mediates HIV-1 Tat-induced up-regulation of VCAM-1/ICAM-1 and subsequent monocyte adhesion in human astrocytes. Free radical biology & medicine 20110301
Activation of the Raf-MEK-ERK pathway is required for neutrophil extracellular trap formation. Nature chemical biology 20110201
The small GTPase RacA mediates intracellular reactive oxygen species production, polarized growth, and virulence in the human fungal pathogen Aspergillus fumigatus. Eukaryotic cell 20110201
Enhanced production of validamycin A by H2O2-induced reactive oxygen species in fermentation of Streptomyces hygroscopicus 5008. Bioresource technology 20110101
Vitamin D metabolites and analogs induce lipoxygenase mRNA expression and activity as well as reactive oxygen species (ROS) production in human bone cell line. The Journal of steroid biochemistry and molecular biology 20110101
Platelet membranes induce airway smooth muscle cell proliferation. Platelets 20110101
[The relationship between reactive oxygen species-dependent activation of p38 MAPK and the expression of tumor necrosis factor-α in cultured cardiomyocytes]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20110101
PKCδ sensitizes neuroblastoma cells to L-buthionine-sulfoximine and etoposide inducing reactive oxygen species overproduction and DNA damage. PloS one 20110101
NOX2, p22phox and p47phox are targeted to the nuclear pore complex in ischemic cardiomyocytes colocalizing with local reactive oxygen species. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101
Diphenyleneiodonium chloride, an inhibitor of reduced nicotinamide adenine dinucleotide phosphate oxidase, suppresses light-dependent induction of clock and DNA repair genes in zebrafish. Biological & pharmaceutical bulletin 20110101
Betanodavirus induces oxidative stress-mediated cell death that prevented by anti-oxidants and zfcatalase in fish cells. PloS one 20110101
p38 Mitogen-activated protein kinase (p38 MAPK) and NADPH Oxidase (NOX) are cytoprotective determinants in the trophozoite-induced apoptosis of peripheral blood mononuclear cells. Cellular immunology 20110101
Endogenous enzymes (NOX and ECSOD) regulate smoke-induced oxidative stress. Free radical biology & medicine 20101215
Proinflammatory effect of cholesterol and its oxidation products on CaCo-2 human enterocyte-like cells: effective protection by epigallocatechin-3-gallate. Free radical biology & medicine 20101215
Reactive oxygen species mediate lysophosphatidic acid induced signaling in ovarian cancer cells. Free radical biology & medicine 20101215
p22phox-dependent NADPH oxidase activity is required for megakaryocytic differentiation. Cell death and differentiation 20101201
Redox regulation of lipopolysaccharide-mediated sulfiredoxin induction, which depends on both AP-1 and Nrf2. The Journal of biological chemistry 20101105
Comparison of in vivo postexercise phosphocreatine recovery and resting ATP synthesis flux for the assessment of skeletal muscle mitochondrial function. American journal of physiology. Cell physiology 20101101
Ellagic acid inhibits oxidized LDL-mediated LOX-1 expression, ROS generation, and inflammation in human endothelial cells. Journal of vascular surgery 20101101
The role of vascular endothelial growth factor-induced activation of NADPH oxidase in choroidal endothelial cells and choroidal neovascularization. The American journal of pathology 20101001
Comparative pharmacology of chemically distinct NADPH oxidase inhibitors. British journal of pharmacology 20101001
Involvement of RAGE, NADPH oxidase, and Ras/Raf-1 pathway in glycated LDL-induced expression of heat shock factor-1 and plasminogen activator inhibitor-1 in vascular endothelial cells. Endocrinology 20100901
Inhibitory effects of antioxidant reagent in reactive oxygen species generation and penetration of appressoria of Alternaria alternata Japanese pear pathotype. Phytopathology 20100901
CXCR2 mediates NADPH oxidase-independent neutrophil extracellular trap formation in cystic fibrosis airway inflammation. Nature medicine 20100901
The basic leucine zipper transcription factor Moatf1 mediates oxidative stress responses and is necessary for full virulence of the rice blast fungus Magnaporthe oryzae. Molecular plant-microbe interactions : MPMI 20100801
NADPH oxidase 4 mediates reactive oxygen species induction of CD146 dimerization in VEGF signal transduction. Free radical biology & medicine 20100715
Effects of areca nut extract on the apoptosis pathways in human neutrophils. Journal of periodontal research 20100601
The pentose phosphate pathway plays an essential role in supporting human sperm capacitation. Fertility and sterility 20100501
Atorvastatin inhibits homocysteine-induced oxidative stress and apoptosis in endothelial progenitor cells involving Nox4 and p38MAPK. Atherosclerosis 20100501
The flavin inhibitor diphenyleneiodonium renders Trichomonas vaginalis resistant to metronidazole, inhibits thioredoxin reductase and flavin reductase, and shuts off hydrogenosomal enzymatic pathways. Molecular and biochemical parasitology 20100501
Effect of Ca2+ on programmed death of guard and epidermal cells of pea leaves. Biochemistry. Biokhimiia 20100501
Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes. Circulation research 20100416
Development of a high-throughput cell-based assay for superoxide production in HL-60 cells. Journal of biomolecular screening 20100401
Evidence for the involvement of NADPH oxidase in ischemia/reperfusion-induced gastric damage via angiotensin II. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100401
Hydrogen peroxide mediates the expression of ascorbate-related genes in response to methanol stimulation in Oncidium. Journal of plant physiology 20100315
Androgens induce oxidative stress and radiation resistance in prostate cancer cells though NADPH oxidase. Prostate cancer and prostatic diseases 20100301
Cellular factors involved in CXCL8 expression induced by glycated serum albumin in vascular smooth muscle cells. Atherosclerosis 20100301
The role of NOX enzymes in ethanol-induced oxidative stress and apoptosis in mouse embryos. Toxicology letters 20100301
Reactive oxygen generated by NADPH oxidase 1 (Nox1) contributes to cell invasion by regulating matrix metalloprotease-9 production and cell migration. The Journal of biological chemistry 20100212
Total body irradiation causes residual bone marrow injury by induction of persistent oxidative stress in murine hematopoietic stem cells. Free radical biology & medicine 20100115
Angiotensin II-induced oxidative stress resets the Ca2+ dependence of Ca2+-calmodulin protein kinase II and promotes a death pathway conserved across different species. Circulation research 20091204
The NADPH-oxidase AtrbohB plays a role in Arabidopsis seed after-ripening. The New phytologist 20091201
The role of 20-hydroxyeicosatetraenoic acid in cerebral arteriolar constriction and the inhibitory effect of propofol. Anesthesia and analgesia 20091201
Roles of NADPH oxidase in occurrence of gastric damage and expression of cyclooxygenase-2 during ischemia/reperfusion in rat stomachs. Journal of pharmacological sciences 20091201
Adenosine 5'-triphosphate stimulates the increase of TGF-beta1 in rat mesangial cells under high-glucose conditions via reactive oxygen species and ERK1/2. Acta pharmacologica Sinica 20091201
Lipoamide dehydrogenase and diaphorase catalyzed conversion of some NO donors to NO and reduction of NO scavenger 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide (PTIO). General physiology and biophysics 20091201
Transcriptional upregulation of mitochondrial uncoupling protein 2 protects against oxidative stress-associated neurogenic hypertension. Circulation research 20091023
Systemic hypoxia enhances exercise-mediated bactericidal and subsequent apoptotic responses in human neutrophils. Journal of applied physiology (Bethesda, Md. : 1985) 20091001
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology 20091001
Atorvastatin attenuates homocysteine-induced apoptosis in human umbilical vein endothelial cells via inhibiting NADPH oxidase-related oxidative stress-triggered p38MAPK signaling. Acta pharmacologica Sinica 20091001
Furo[3',2':3,4]naphtho[1,2-d]imidazole derivatives as potential inhibitors of inflammatory factors in sepsis. Bioorganic & medicinal chemistry 20090915
Chlamydophila pneumoniae triggers release of CCL20 and vascular endothelial growth factor from human bronchial epithelial cells through enhanced intracellular oxidative stress and MAPK activation. Journal of clinical immunology 20090901
Nox4 mediates the expression of plasminogen activator inhibitor-1 via p38 MAPK pathway in cultured human endothelial cells. Thrombosis research 20090901
Activation of NF-kappaB by palmitate in endothelial cells: a key role for NADPH oxidase-derived superoxide in response to TLR4 activation. Arteriosclerosis, thrombosis, and vascular biology 20090901
Bcr-Abl-mediated redox regulation of the PI3K/AKT pathway. Leukemia 20090801
Real-time imaging of novel spatial and temporal responses to photodynamic stress. Free radical biology & medicine 20090801
ROS and PDGF-beta [corrected] receptors are critically involved in indoxyl sulfate actions that promote vascular smooth muscle cell proliferation and migration. American journal of physiology. Cell physiology 20090801
Macrophage inflammatory protein-1beta induced cell adhesion with increased intracellular reactive oxygen species. Journal of molecular and cellular cardiology 20090701
[NADPH oxidase-derived reactive oxygen species involved in angiotensin II-induced monocyte chemoattractant protein-1 expression in mesangial cells]. Zhonghua bing li xue za zhi = Chinese journal of pathology 20090701
NADPH oxidase and ERK1/2 are involved in cadmium induced-STAT3 activation in HepG2 cells. Toxicology letters 20090622
Antioxidant potential of Minocycline in Japanese Encephalitis Virus infection in murine neuroblastoma cells: correlation with membrane fluidity and cell death. Neurochemistry international 20090601
Angiotensin II stimulates MCP-1 production in rat glomerular endothelial cells via NAD(P)H oxidase-dependent nuclear factor-kappa B signaling. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20090601
The blood platelets contribution to innate host defense - what they have learned from their big brothers. Biotechnology journal 20090601
Association of NAD(P)H oxidase with glucose-induced insulin secretion by pancreatic beta-cells. Endocrinology 20090501
The mechanisms involved in seed dormancy alleviation by hydrogen cyanide unravel the role of reactive oxygen species as key factors of cellular signaling during germination. Plant physiology 20090501
Free Fatty Acids and Methyl Jasmonate Trigger Defense Reactions in Laminaria digitata. Plant & cell physiology 20090401
Synthesis, anti-inflammatory, and antioxidant activities of 18beta-glycyrrhetinic acid derivatives as chemical mediators and xanthine oxidase inhibitors. Bioorganic & medicinal chemistry 20090401
Cigarette smoke extract induces cytosolic phospholipase A2 expression via NADPH oxidase, MAPKs, AP-1, and NF-kappaB in human tracheal smooth muscle cells. Free radical biology & medicine 20090401
Nitric oxide production occurs downstream of reactive oxygen species in guard cells during stomatal closure induced by chitosan in abaxial epidermis of Pisum sativum. Planta 20090301
An increase in the concentration of abscisic acid is critical for nitric oxide-mediated plant adaptive responses to UV-B irradiation. The New phytologist 20090301
Selective radiation-induced generation of 2-deoxyribonolactone lesions in DNA mediated by aromatic iodonium derivatives. Radiation research 20090301
Suppression of retinal peroxisome proliferator-activated receptor gamma in experimental diabetes and oxygen-induced retinopathy: role of NADPH oxidase. Investigative ophthalmology & visual science 20090201
Type II NADH dehydrogenase of the respiratory chain of Plasmodium falciparum and its inhibitors. Bioorganic & medicinal chemistry letters 20090201
Exogenous cadaverine induces oxidative burst and reduces cadaverine conjugate content in the common ice plant. Journal of plant physiology 20090101
NADPH oxidase mediates beta-amyloid peptide-induced activation of ERK in hippocampal organotypic cultures. Molecular brain 20090101
Regulation of soluble epoxide hydrolase (sEH) in mice with diabetes: high glucose suppresses sEH expression. Drug metabolism and pharmacokinetics 20090101
Static pressure promotes rat aortic smooth muscle cell proliferation via upregulation of volume-regulated chloride channel. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20090101
NPR1 protein regulates pathogenic and symbiotic interactions between Rhizobium and legumes and non-legumes. PloS one 20090101
Fast, transient and specific intracellular ROS changes in living root hair cells responding to Nod factors (NFs). The Plant journal : for cell and molecular biology 20081201
Early events in signalling high-temperature stress in tobacco BY2 cells involve alterations in membrane fluidity and enhanced hydrogen peroxide production. Plant, cell & environment 20081201
Differential role of diphenyleneiodonium, a flavoenzyme inhibitor, on p53-dependent and -independent cell cycle progression. International journal of oncology 20081201
Variations in creatine kinase activity and reactive oxygen species levels are involved in capacitation of bovine spermatozoa. Andrologia 20081201
Impaired insulin secretion by diphenyleneiodium associated with perturbation of cytosolic Ca2+ dynamics in pancreatic beta-cells. Endocrinology 20081101
Potent antioxidant role of pirfenidone in experimental cirrhosis. European journal of pharmacology 20081024
Activation of NADPH oxidase 1 in tumour colon epithelial cells. The Biochemical journal 20081001
Involvement of hydrogen peroxide in leaf abscission signaling, revealed by analysis with an in vitro abscission system in Capsicum plants. The Plant journal : for cell and molecular biology 20081001
Classical inhibitors of NOX NAD(P)H oxidases are not specific. Current drug metabolism 20081001
Alternation of retinoic acid induced neural differentiation of P19 embryonal carcinoma cells by reduction of reactive oxygen species intracellular production. Neuro endocrinology letters 20081001
DNA damage in human mononuclear cells induced by bacterial endotoxin. Bulletin of experimental biology and medicine 20080901
Dynein light chain LC8 negatively regulates NF-kappaB through the redox-dependent interaction with IkappaBalpha. The Journal of biological chemistry 20080829
Redox survival signalling in retina-derived 661W cells. Cell death and differentiation 20080801
Strain differences regarding susceptibility to ursolic acid-induced interleukin-1beta release in murine macrophages. Life sciences 20080704
Volume-sensitive NADPH oxidase activity and taurine efflux in NIH3T3 mouse fibroblasts. American journal of physiology. Cell physiology 20080601
Paradoxical effect of diphenyleneiodonium in inducing DNA damage and apoptosis. Free radical research 20080601
NADPH oxidases are involved in differentiation and pathogenicity in Botrytis cinerea. Molecular plant-microbe interactions : MPMI 20080601
TRPV1 mediates cell death in rat synovial fibroblasts through calcium entry-dependent ROS production and mitochondrial depolarization. Biochemical and biophysical research communications 20080516
Renal (pro)renin receptor upregulation in diabetic rats through enhanced angiotensin AT1 receptor and NADPH oxidase activity. Experimental physiology 20080501
A critical role for ureides in dark and senescence-induced purine remobilization is unmasked in the Atxdh1 Arabidopsis mutant. The Plant journal : for cell and molecular biology 20080501
Diphenyleneiodonium acutely inhibits reactive oxygen species production by mitochondrial complex I during reverse, but not forward electron transport. Biochimica et biophysica acta 20080501
Local production of O2- by NAD(P)H oxidase in the sarcoplasmic reticulum of coronary arterial myocytes: cADPR-mediated Ca2+ regulation. Cellular signalling 20080401
TNF-alpha/cycloheximide-induced apoptosis in intestinal epithelial cells requires Rac1-regulated reactive oxygen species. American journal of physiology. Gastrointestinal and liver physiology 20080401
Intracellular adhesion molecule-1 up-regulation on thyrocytes by iodine of non-obese diabetic.H2(h4) mice is reactive oxygen species-dependent. Clinical and experimental immunology 20080401
Role of 12/15-lipoxygenase in the expression of MCP-1 in mouse macrophages. American journal of physiology. Heart and circulatory physiology 20080401
Reactive oxygen species are generated through a BLT2-linked cascade in Ras-transformed cells. Free radical biology & medicine 20080215
Synergistic induction of osteopontin by aldosterone and inflammatory cytokines in mesangial cells. Journal of cellular biochemistry 20080201
Activation of natriuretic peptide receptor-C attenuates the enhanced oxidative stress in vascular smooth muscle cells from spontaneously hypertensive rats: implication of Gialpha protein. Journal of molecular and cellular cardiology 20080201
Lipid rafts keep NADPH oxidase in the inactive state in human renal proximal tubule cells. Hypertension (Dallas, Tex. : 1979) 20080201
Production of superoxide anion and hydrogen peroxide by capacitating buffalo (Bubalus bubalis) spermatozoa. Animal reproduction science 20080130
Regulation of normal cell cycle progression by flavin-containing oxidases. Oncogene 20080103
Nox1-based NADPH oxidase is the major source of UVA-induced reactive oxygen species in human keratinocytes. The Journal of investigative dermatology 20080101
Trichomonas vaginalis: reactive oxygen species mediates caspase-3 dependent apoptosis of human neutrophils. Experimental parasitology 20080101
NADPH oxidase plays a crucial role in the activation of pancreatic stellate cells. American journal of physiology. Gastrointestinal and liver physiology 20080101
Hydrogen peroxide is involved in high blue light-induced chloroplast avoidance movements in Arabidopsis. Journal of experimental botany 20080101
Vibrio vulnificus-induced death of Jurkat T-cells requires activation of p38 mitogen-activated protein kinase by NADPH oxidase-derived reactive oxygen species. Cellular immunology 20080101
Signal transduction pathways and haem oxygenase induction in soybean leaves subjected to salt stress. Redox report : communications in free radical research 20080101
Strboh A homologue of NADPH oxidase regulates wound-induced oxidative burst and facilitates wound-healing in potato tubers. Planta 20071201
NADPH oxidase deficiency results in reduced alveolar macrophage 5-lipoxygenase expression and decreased leukotriene synthesis. Journal of leukocyte biology 20071201
Acyl chain-dependent effect of lysophosphatidylcholine on human neutrophils. Journal of leukocyte biology 20071201
Sphingosine-1-phosphate-induced oxygen free radical generation in smooth muscle cell migration requires Galpha12/13 protein-mediated phospholipase C activation. Journal of vascular surgery 20071201
Reactive oxygen species regulate angiogenesis and tumor growth through vascular endothelial growth factor. Cancer research 20071115
Reactive oxygen species generation by the ethylene-bis-dithiocarbamate (EBDC) fungicide mancozeb and its contribution to neuronal toxicity in mesencephalic cells. Neurotoxicology 20071101
High glucose attenuates protein S-nitrosylation in endothelial cells: role of oxidative stress. Diabetes 20071101
Inhibition of NADPH oxidase subunits translocation by tea catechin EGCG in mast cell. Biochemical and biophysical research communications 20071019
Pro-inflammatory cytokines increase reactive oxygen species through mitochondria and NADPH oxidase in cultured RPE cells. Experimental eye research 20071001
[Changes in H2O2 and salicylic acid contents as well as plasma membrane H+-ATPase activity and their relations in pea leaves during thermotolerance induction]. Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology 20071001
Mechanism of apoptosis induced by apigenin in HepG2 human hepatoma cells: involvement of reactive oxygen species generated by NADPH oxidase. Archives of pharmacal research 20071001
Manganese chloride stimulates rat microglia to release hydrogen peroxide. Toxicology letters 20070910
Hypoxia activates c-Jun N-terminal kinase via Rac1-dependent reactive oxygen species production in hepatocytes. Shock (Augusta, Ga.) 20070901
Reactive oxygen species mediate ET-1-induced activation of ERK1/2 signaling in cultured feline esophageal smooth muscle cells. Archives of pharmacal research 20070901
Reactive oxygen species, ABA and nitric oxide interactions on the germination of warm-season C4-grasses. Planta 20070801
Activation of NADPH oxidase by transforming growth factor-beta in hepatocytes mediates up-regulation of epidermal growth factor receptor ligands through a nuclear factor-kappaB-dependent mechanism. The Biochemical journal 20070715
Diphenylene iodonium stimulates glucose uptake in skeletal muscle cells through mitochondrial complex I inhibition and activation of AMP-activated protein kinase. Cellular signalling 20070701
Crocetin attenuates palmitate-induced insulin insensitivity and disordered tumor necrosis factor-alpha and adiponectin expression in rat adipocytes. British journal of pharmacology 20070701
Activation and inactivation of the volume-sensitive taurine leak pathway in NIH3T3 fibroblasts and Ehrlich Lettre ascites cells. American journal of physiology. Cell physiology 20070701
Angiotensin-(1-7) blocks the angiotensin II-stimulated superoxide production. Pharmacological research 20070701
Carbon black particles increase reactive oxygen species formation in rat alveolar macrophages in vitro. Archives of toxicology 20070601
Optimal reactive oxygen species concentration and p38 MAP kinase are required for coronary collateral growth. American journal of physiology. Heart and circulatory physiology 20070601
Glutamate release from activated microglia requires the oxidative burst and lipid peroxidation. Journal of neurochemistry 20070601
Synthetic 2',5'-dimethoxychalcones as G(2)/M arrest-mediated apoptosis-inducing agents and inhibitors of nitric oxide production in rat macrophages. European journal of medicinal chemistry 20070501
NAD(P)H oxidases regulate HIF-2alpha protein expression. The Journal of biological chemistry 20070316
Bone-marrow derived hematopoietic stem/progenitor cells express multiple isoforms of NADPH oxidase and produce constitutively reactive oxygen species. Biochemical and biophysical research communications 20070223
Diphenyleneiodonium and dimethylsulfoxide for treatment of reperfusion injury in cerebral ischemia of the rat. Brain research 20070209
Insulin-induced activation of hypoxia-inducible factor-1 requires generation of reactive oxygen species by NADPH oxidase. American journal of physiology. Heart and circulatory physiology 20070201
Diphenyleneiodonium induces ROS-independent p53 expression and apoptosis in human RPE cells. FEBS letters 20070123
Activation of Ca2+ -activated potassium channels is involved in lysophosphatidylcholine-induced monocyte adhesion to endothelial cells. Atherosclerosis 20070101
HUVECs from newborns with a strong family history of diabetes show diminished ROS synthesis in the presence of high glucose concentrations. Diabetes/metabolism research and reviews 20070101
Tobacco nectaries express a novel NADPH oxidase implicated in the defense of floral reproductive tissues against microorganisms. Plant physiology 20070101
A transient decrease in reactive oxygen species in roots leads to root hair deformation in the legume-rhizobia symbiosis. The New phytologist 20070101
Chemiluminescent picture of diphenyleneiodonium-inhibited NADPH oxidase: a bimodal process and its logistic-exponential model-based description. Luminescence : the journal of biological and chemical luminescence 20070101
Diphenyleneiodonium suppresses apoptosis in cerulein-stimulated pancreatic acinar cells. The international journal of biochemistry & cell biology 20070101
Pigment epithelium-derived factor (PEDF) inhibits angiotensin II-induced smooth muscle cell proliferation through its anti-oxidative properties. Protein and peptide letters 20070101
Inhibition of NAD(P)H oxidase attenuates aggregation of platelets from high-risk cardiac patients with aspirin resistance. Pharmacological reports : PR 20070101
Dehydroascorbate uptake is impaired in the early response of Arabidopsis plant cell cultures to cadmium. Journal of experimental botany 20070101
Simvastatin inhibits lipopolysaccharide-induced tumor necrosis factor-alpha expression in neonatal rat cardiomyocytes: The role of reactive oxygen species. Biochemical and biophysical research communications 20061229
Effects of hydrogen sulfide on homocysteine-induced oxidative stress in vascular smooth muscle cells. Biochemical and biophysical research communications 20061215
Endotoxin induces toll-like receptor 4 expression in vascular smooth muscle cells via NADPH oxidase activation and mitogen-activated protein kinase signaling pathways. Arteriosclerosis, thrombosis, and vascular biology 20061201
Parthenolide-induced apoptosis in multiple myeloma cells involves reactive oxygen species generation and cell sensitivity depends on catalase activity. Apoptosis : an international journal on programmed cell death 20061201
A key role for the microglial NADPH oxidase in APP-dependent killing of neurons. Neurobiology of aging 20061101
Abscisic acid is a key inducer of hydrogen peroxide production in leaves of maize plants exposed to water stress. Plant & cell physiology 20061101
The reactive oxygen species are involved in resistance responses of wheat to the Russian wheat aphid. Journal of plant physiology 20061101
Effect of cis-urocanic acid on bovine neutrophil generation of reactive oxygen species. Journal of dairy science 20061101
Activation of nicotinamide adenine dinucleotide phosphate (reduced form) oxidase by advanced glycation end products links oxidative stress to altered retinal vascular endothelial growth factor expression. Metabolism: clinical and experimental 20061101
Carbon monoxide and bilirubin from heme oxygenase-1 suppresses reactive oxygen species generation and plasminogen activator inhibitor-1 induction. Molecular and cellular biochemistry 20061001
Angiopoietin-1-induced angiogenesis is modulated by endothelial NADPH oxidase. American journal of physiology. Heart and circulatory physiology 20061001
[The mechanism of ABA-induced apoplastic H2O2 accumulation in maize leaves]. Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology 20061001
NADPH-oxidase activity is elevated in penumbral and non-ischemic cerebral arteries following stroke. Brain research 20060921
Reactive oxygen species mediate phorbol ester-stimulated cAMP response in human eosinophils. European journal of pharmacology 20060814
Ras mutation promotes p53 activation and apoptosis of skin keratinocytes. Carcinogenesis 20060801
Salvianolic acid B from Salvia miltiorrhiza inhibits tumor necrosis factor-alpha (TNF-alpha)-induced MMP-2 upregulation in human aortic smooth muscle cells via suppression of NAD(P)H oxidase-derived reactive oxygen species. Journal of molecular and cellular cardiology 20060701
Inhibition of NADPH oxidase 4 activates apoptosis via the AKT/apoptosis signal-regulating kinase 1 pathway in pancreatic cancer PANC-1 cells. Oncogene 20060622
Indoxyl sulfate induces complex redox alterations in mesangial cells. American journal of physiology. Renal physiology 20060601
Aspirin and PPAR-alpha activators inhibit monocyte chemoattractant protein-1 expression induced by high glucose concentration in human endothelial cells. Vascular pharmacology 20060601
Heterotrimeric G protein G alpha13-induced induction of cytokine mRNAs through two distinct pathways in cardiac fibroblasts. Journal of pharmacological sciences 20060601
Reactive oxygen species induced by shear stress mediate cell death in Bacillus subtilis. Biotechnology and bioengineering 20060505
Notoginsenoside R1 inhibits TNF-alpha-induced fibronectin production in smooth muscle cells via the ROS/ERK pathway. Free radical biology & medicine 20060501
NOX4 as an oxygen sensor to regulate TASK-1 activity. Cellular signalling 20060401
Statins inhibit hypoxia-induced endothelial proliferation by preventing calcium-induced ROS formation. Atherosclerosis 20060401
Angiotensin II-stimulated collagen production in cardiac fibroblasts is mediated by reactive oxygen species. Journal of hypertension 20060401
Respiratory burst and NAD(P)H oxidase activity are involved in capacitation of cryopreserved bovine spermatozoa. Theriogenology 20060301
Penicillamine administration reverses the inhibitory effect of hyperhomocysteinaemia on endothelium-dependent relaxation and superoxide formation in the aorta of the rabbit. European journal of pharmacology 20060215
Wound-induced expression of the ferulate 5-hydroxylase gene in Camptotheca acuminata. Biochimica et biophysica acta 20060201
Chemical manipulation of glucose metabolism in porcine oocytes: effects on nuclear and cytoplasmic maturation in vitro. Reproduction (Cambridge, England) 20060201
Synthetic smooth muscle cell phenotype is associated with increased nicotinamide adenine dinucleotide phosphate oxidase activity: effect on collagen secretion. Journal of vascular surgery 20060201
Hypoxic reperfusion of the ischemic heart and oxygen radical generation. American journal of physiology. Heart and circulatory physiology 20060101
Hyaluronan fragments activate nitric oxide synthase and the production of nitric oxide by articular chondrocytes. The international journal of biochemistry & cell biology 20060101
Relationship of intracellular calcium and oxygen radicals to Cisplatin-related renal cell injury. Journal of pharmacological sciences 20060101
Production of reactive oxygen species in mitochondria of HeLa cells under oxidative stress. Biochimica et biophysica acta 20060101
Flavin-containing polyamine oxidase is a hydrogen peroxide source in the oxidative response to the protein phosphatase inhibitor cantharidin in Zea mays L. Journal of experimental botany 20060101
Redox-dependent expression of cyclin D1 and cell proliferation by Nox1 in mouse lung epithelial cells. Antioxidants & redox signaling 20060101
Activation of AP-1 through reactive oxygen species by angiotensin II in rat cardiomyocytes. Free radical biology & medicine 20051215
Endogenous thioredoxin is required for redox cycling of anthracyclines and p53-dependent apoptosis in cancer cells. The Journal of biological chemistry 20051202
Role of mitochondria in tamoxifen-induced rapid death of MCF-7 breast cancer cells. Apoptosis : an international journal on programmed cell death 20051201
Oxidative stress contributes to the enhanced expression of Gialpha proteins and adenylyl cyclase signaling in vascular smooth muscle cells from spontaneously hypertensive rats. Journal of hypertension 20051201
Effect of p47phox gene deletion on ROS production and oxygen sensing in mouse carotid body chemoreceptor cells. American journal of physiology. Lung cellular and molecular physiology 20051201
Activation of endothelial NADPH oxidase during normoxic lung ischemia is KATP channel dependent. American journal of physiology. Lung cellular and molecular physiology 20051201
Rac1-NADPH oxidase-regulated generation of reactive oxygen species mediates glutamate-induced apoptosis in SH-SY5Y human neuroblastoma cells. Free radical research 20051201
Oxidative stress-dependent conversion of hydrogen sulfide to sulfite by activated neutrophils. Shock (Augusta, Ga.) 20051201
Ethanol-induced sensitization to endotoxin in Kupffer cells is dependent upon oxidative stress. Alcoholism, clinical and experimental research 20051201
Iron-dependent lysosomal destabilization initiates silica-induced apoptosis in murine macrophages. Toxicology letters 20051115
Coronary microvascular endothelial cell growth regulates expression of the gene encoding p22-phox. Free radical biology & medicine 20051115
Acrosome reaction in bovine spermatozoa: role of reactive oxygen species and lactate dehydrogenase C4. Biochimica et biophysica acta 20051030
Influence of lead (Pb2+) on the reactions of in vitro cultured rat aorta to 5-hydroxytryptamine. Toxicology letters 20051015
Alterations in redox homeostasis and prostaglandins impair endothelial-dependent vasodilation in euglycemic autoimmune nonobese diabetic mice. Free radical biology & medicine 20051015
Hypertonic induction of COX-2 in collecting duct cells by reactive oxygen species of mitochondrial origin. The Journal of biological chemistry 20051014
NADPH oxidase-derived superoxide anion mediates angiotensin II-induced pressor effect via activation of p38 mitogen-activated protein kinase in the rostral ventrolateral medulla. Circulation research 20051014
Lipopolysaccharide-induced alterations in oxygen consumption and radical generation in endothelial cells. Molecular and cellular biochemistry 20051001
Insulin-stimulated NAD(P)H oxidase activity increases migration of cultured vascular smooth muscle cells. American journal of hypertension 20051001
Role of NADPH oxidase-mediated generation of reactive oxygen species in the mechanism of apoptosis induced by phenolic acids in HepG2 human hepatoma cells. Archives of pharmacal research 20051001
Adhesion and Rac1-dependent regulation of biglycan gene expression by transforming growth factor-beta. Evidence for oxidative signaling through NADPH oxidase. The Journal of biological chemistry 20050930
Redox response of the endogenous calcineurin inhibitor Adapt 78. Free radical biology & medicine 20050915
Role of NAD(P)H oxidase in the regulation of cardiac L-type Ca2+ channel function during acute hypoxia. Cardiovascular research 20050901
Role of phagocyte oxidase in UVA-induced oxidative stress and apoptosis in keratinocytes. The Journal of investigative dermatology 20050901
Statin attenuates high glucose-induced and angiotensin II-induced MAP kinase activity through inhibition of NAD(P)H oxidase activity in cultured mesangial cells. Medicinal chemistry (Shariqah (United Arab Emirates)) 20050901
Effect of sildenafil citrate and a nitric oxide donating sildenafil derivative, NCX 911, on cavernosal relaxation and superoxide formation in hypercholesterolaemic rabbits. European journal of pharmacology 20050711
NADPH oxidase mediates interleukin-6 expression in cerulein-stimulated pancreatic acinar cells. The international journal of biochemistry & cell biology 20050701
Cytochrome P4502E1 primes macrophages to increase TNF-alpha production in response to lipopolysaccharide. American journal of physiology. Gastrointestinal and liver physiology 20050701
Galpha12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts. The Journal of biological chemistry 20050617
NAD(P)H oxidase plays a crucial role in PDGF-induced proliferation of hepatic stellate cells. Hepatology (Baltimore, Md.) 20050601
Selective and irreversible cell cycle inhibition by diphenyleneiodonium. Molecular cancer therapeutics 20050601
Systemic induction of H2O2 in pea seedlings pretreated by wounding and exogenous jasmonic acid. Science in China. Series C, Life sciences 20050601
Diphenyleneiodium (DPI) reduces oxalate ion- and calcium oxalate monohydrate and brushite crystal-induced upregulation of MCP-1 in NRK 52E cells. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050501
Induction of apoptosis and modulation of production of reactive oxygen species in human endothelial cells by diphenyleneiodonium. Biochemical pharmacology 20050415
Involvement of UVB-induced reactive oxygen species in TGF-beta biosynthesis and activation in keratinocytes. Free radical biology & medicine 20050401
Essential role of ATF-1 in induction of NOX1, a catalytic subunit of NADPH oxidase: involvement of mitochondrial respiratory chain. The Biochemical journal 20050301
Serum withdrawal kills U937 cells by inducing a positive mutual interaction between reactive oxygen species and phosphoinositide 3-kinase. Cellular signalling 20050201
PKC-delta-dependent activation of oxidative stress in adipocytes of obese and insulin-resistant mice: role for NADPH oxidase. American journal of physiology. Endocrinology and metabolism 20050201
The contribution of Nox4 to NADPH oxidase activity in mouse vascular smooth muscle. Cardiovascular research 20050201
Inhibitors of NADPH oxidase reduce the organ injury in hemorrhagic shock. Shock (Augusta, Ga.) 20050201
Effects of L-mono methyl-arginine, N-acetyl-cysteine and diphenyleniodonium on free radical release in C6 glial cells enriched in hexacosenoic acid. Neurochemical research 20050201
NADPH oxidase produces reactive oxygen species and maintains survival of rat astrocytes. Cell biochemistry and function 20050101
Inhibition of Nox-4 activity by plumbagin, a plant-derived bioactive naphthoquinone. The Journal of pharmacy and pharmacology 20050101
Hyperglycemia potentiates H(2)O(2) production in adipocytes and enhances insulin signal transduction: potential role for oxidative inhibition of thiol-sensitive protein-tyrosine phosphatases. Antioxidants & redox signaling 20050101
Mechanism and characteristics of stimuli-dependent ROS generation in undifferentiated HL-60 cells. Antioxidants & redox signaling 20050101
Arrestin regulates MAPK activation and prevents NADPH oxidase-dependent death of cells expressing CXCR2. The Journal of biological chemistry 20041119
Diphenyleneiodonium inhibits the cell redox metabolism and induces oxidative stress. The Journal of biological chemistry 20041112
Preconditioning by isoflurane is mediated by reactive oxygen species generated from mitochondrial electron transport chain complex III. Anesthesia and analgesia 20041101
Exogenous NADPH increases cerebral blood flow through NADPH oxidase-dependent and -independent mechanisms. Arteriosclerosis, thrombosis, and vascular biology 20041001
G2 cell cycle arrest, down-regulation of cyclin B, and induction of mitotic catastrophe by the flavoprotein inhibitor diphenyleneiodonium. Molecular cancer therapeutics 20041001
Root growth inhibition by aluminum is probably caused by cell death due to peroxidase-mediated hydrogen peroxide production. Protoplasma 20041001
Propofol scavenges reactive oxygen species and inhibits the protein nitration induced by activated polymorphonuclear neutrophils. European journal of pharmacology 20040919
17beta-estradiol inhibits cyclic strain-induced endothelin-1 gene expression within vascular endothelial cells. American journal of physiology. Heart and circulatory physiology 20040901
Cell activating capacity of 50 Hz magnetic fields to release reactive oxygen intermediates in human umbilical cord blood-derived monocytes and in Mono Mac 6 cells. Free radical research 20040901
Nitroaspirins and morpholinosydnonimine but not aspirin inhibit the formation of superoxide and the expression of gp91phox induced by endotoxin and cytokines in pig pulmonary artery vascular smooth muscle cells and endothelial cells. Circulation 20040831
Reactive oxygen species mediate Endothelin-1-induced activation of ERK1/2, PKB, and Pyk2 signaling, as well as protein synthesis, in vascular smooth muscle cells. Free radical biology & medicine 20040715
NADPH oxidase-derived oxidant stress is critical for neutrophil cytotoxicity during endotoxemia. American journal of physiology. Gastrointestinal and liver physiology 20040701
Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system. The American journal of pathology 20040701
Counteracting effects of NADPH oxidase and the Na+/Ca2+ exchanger on membrane repolarisation and store-operated uptake of Ca2+ by chemoattractant-activated human neutrophils. Biochemical pharmacology 20040615
Cadmium induces caspase-independent apoptosis in liver Hep3B cells: role for calcium in signaling oxidative stress-related impairment of mitochondria and relocation of endonuclease G and apoptosis-inducing factor. Free radical biology & medicine 20040615
Cell surface oxygen consumption by mitochondrial gene knockout cells. Biochimica et biophysica acta 20040607
Morphine-induced macrophage apoptosis: oxidative stress and strategies for modulation. Journal of leukocyte biology 20040601
Stable compounds of cigarette smoke induce endothelial superoxide anion production via NADPH oxidase activation. Arteriosclerosis, thrombosis, and vascular biology 20040601
Angiotensin II increases Pax-2 expression in fetal kidney cells via the AT2 receptor. Journal of the American Society of Nephrology : JASN 20040601
Transmembrane electron transport in sealed and NAD(P)H-loaded right-side-out plasma membrane vesicles isolated from maize (Zea mays L.) roots. Journal of experimental botany 20040601
Chitinase induced by jasmonic acid, methyl jasmonate, ethylene and protein phosphatase inhibitors in rice. Molecular biology reports 20040601
NADPH oxidase-mediated generation of reactive oxygen species is critically required for survival of undifferentiated human promyelocytic leukemia cell line HL-60. Free radical research 20040601
Upregulation of NAD(P)H oxidase 1 in hypoxia activates hypoxia-inducible factor 1 via increase in reactive oxygen species. Free radical biology & medicine 20040515
The superoxide-generating oxidase Nox1 is functionally required for Ras oncogene transformation. Cancer research 20040515
Redox activity associated with the maturation and capacitation of mammalian spermatozoa. Free radical biology & medicine 20040415
Glucuronic acid is a novel inducer of heat shock response. Molecular and cellular biochemistry 20040401
Involvement of NADPH oxidase in hydrogen peroxide accumulation by Aspergillus niger elicitor-induced Taxus chinensis cell cultures. Journal of plant physiology 20040401
Peroxynitrite formation from the simultaneous reduction of nitrite and oxygen by xanthine oxidase. FEBS letters 20040326
NADH oxidase activity of rat cardiac sarcoplasmic reticulum regulates calcium-induced calcium release. Circulation research 20040305
Oligogalacturonide signal transduction, induction of defense-related responses and protection of grapevine against Botrytis cinerea. Planta 20040301
Integration of multiple downstream signals determines the net effect of insulin on MAP kinase vs. PI 3'-kinase activation: potential role of insulin-stimulated H(2)O(2). Cellular signalling 20040301
Homocysteine enhances superoxide anion release and NADPH oxidase assembly by human neutrophils. Effects on MAPK activation and neutrophil migration. Atherosclerosis 20040201
Alpha-picolinic acid, a fungal toxin and mammal apoptosis-inducing agent, elicits hypersensitive-like response and enhances disease resistance in rice. Cell research 20040201
Source of early reactive oxygen species in the apoptosis induced by transforming growth factor-beta in fetal rat hepatocytes. Free radical biology & medicine 20040101
Glycated albumin induces superoxide generation in mesangial cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20040101
Fc epsilon RI signaling of mast cells activates intracellular production of hydrogen peroxide: role in the regulation of calcium signals. Journal of immunology (Baltimore, Md. : 1950) 20031201
Angiotensin II mediates LDL-induced superoxide generation in mesangial cells. American journal of physiology. Renal physiology 20031101
Platelets induce reactive oxygen species-dependent growth of human skin fibroblasts. European journal of cell biology 20031101
Reactive oxygen species sensitivity of angiotensin II-dependent translation initiation in vascular smooth muscle cells. The Journal of biological chemistry 20030919
High glucose-suppressed endothelin-1 Ca2+ signaling via NADPH oxidase and diacylglycerol-sensitive protein kinase C isozymes in mesangial cells. The Journal of biological chemistry 20030905
Hemispheric dissociation of the involvement of NOS isoforms in memory for discriminated avoidance in the chick. Learning & memory (Cold Spring Harbor, N.Y.) 20030901
Homocysteine mediated expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human monocytes. Circulation research 20030822
A potential mechanism for the impairment of nitric oxide formation caused by prolonged oral exposure to arsenate in rabbits. Free radical biology & medicine 20030701
Increase in anthraquinone content in Rubia cordifolia cells transformed by rol genes does not involve activation of the NADPH oxidase signaling pathway. Biochemistry. Biokhimiia 20030701
Effects of Ca(2+) channel blockers and protein kinase/phosphatase inhibitors on growth and anthraquinone production in Rubia cordifolia callus cultures transformed by the rolB and rolC genes. Planta 20030701
Oxidized low-density lipoprotein (oxLDL) triggers hypoxia-inducible factor-1alpha (HIF-1alpha) accumulation via redox-dependent mechanisms. Blood 20030615
Red wine polyphenolic compounds inhibit vascular endothelial growth factor expression in vascular smooth muscle cells by preventing the activation of the p38 mitogen-activated protein kinase pathway. Arteriosclerosis, thrombosis, and vascular biology 20030601
Protein-tyrosine phosphatase activity in human adipocytes is strongly correlated with insulin-stimulated glucose uptake and is a target of insulin-induced oxidative inhibition. Metabolism: clinical and experimental 20030601
Signaling role of intracellular iron in NF-kappaB activation. The Journal of biological chemistry 20030516
Cyclosporin A disrupts bradykinin signaling through superoxide. Hypertension (Dallas, Tex. : 1979) 20030501
Radiation-activated nuclease activity of o,o'-Diphenyleneiodonium cations (DPI): a reductively initiated chain reaction involving the C1' chemistry. Radiation research 20030401
Calcium signalling is altered in myeloid cells with a deficiency in NADPH oxidase activity. Clinical and experimental immunology 20030401
Reactive oxygen species and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase mediate hyperoxia-induced cell death in lung epithelium. American journal of respiratory cell and molecular biology 20030301
Metallothionein prevents diabetes-induced deficits in cardiomyocytes by inhibiting reactive oxygen species production. Diabetes 20030301
Modulation of vascular smooth muscle cell alignment by cyclic strain is dependent on reactive oxygen species and P38 mitogen-activated protein kinase. Journal of vascular surgery 20030301
Homocysteine enhances TIMP-1 expression and cell proliferation associated with NADH oxidase in rat mesangial cells. Kidney international 20030301
DPI induces mitochondrial superoxide-mediated apoptosis. Free radical biology & medicine 20030215
Hyperoxia-induced NAD(P)H oxidase activation and regulation by MAP kinases in human lung endothelial cells. American journal of physiology. Lung cellular and molecular physiology 20030101
[Dependence of EGF receptor and STAT factor activation on redox of A431 cells]. Tsitologiia 20030101
Fluorescence microplate assay for the detection of oxidative burst products in tobacco cell suspensions using 2',7'-dichlorofluorescein. Methods in cell science : an official journal of the Society for In Vitro Biology 20030101
Angiotensin II induces a rapid and transient increase of reactive oxygen species. Antioxidants & redox signaling 20021201
Antioxidants inhibit endothelin-1 (1-31)-induced proliferation of vascular smooth muscle cells via the inhibition of mitogen-activated protein (MAP) kinase and activator protein-1 (AP-1). Biochemical pharmacology 20021115
CNS neurons express two distinct plasma membrane electron transport systems implicated in neuronal viability. Journal of neurochemistry 20021101
Vascular NAD(P)H oxidase triggers delayed cerebral vasospasm after subarachnoid hemorrhage in rats. Stroke 20021101
Mitochondrial reactive oxygen species trigger calcium increases during hypoxia in pulmonary arterial myocytes. Circulation research 20021018
Alpha-tocopherol decreases superoxide anion release in human monocytes under hyperglycemic conditions via inhibition of protein kinase C-alpha. Diabetes 20021001
Critical role of NADPH oxidase-derived reactive oxygen species in generating Ca2+ oscillations in human aortic endothelial cells stimulated by histamine. The Journal of biological chemistry 20020906
Reactive oxygen species in the elongation zone of maize leaves are necessary for leaf extension. Plant physiology 20020801
Mechanism of superoxide anion production by hepatic sinusoidal endothelial cells and Kupffer cells during short-term ethanol perfusion in the rat. Liver 20020801
Measurement of phagosomal pH of normal and CGD-like human neutrophils by dual fluorescence flow cytometry. Cytometry 20020701
Aged garlic extract enhances production of nitric oxide. Life sciences 20020621
Mycobacterium tuberculosis promotes apoptosis in human neutrophils by activating caspase-3 and altering expression of Bax/Bcl-xL via an oxygen-dependent pathway. Journal of immunology (Baltimore, Md. : 1950) 20020615
RopGAP4-dependent Rop GTPase rheostat control of Arabidopsis oxygen deprivation tolerance. Science (New York, N.Y.) 20020614
An NAD(P)H oxidase regulates growth and transcription in melanoma cells. American journal of physiology. Cell physiology 20020601
Production of superoxide through NADH oxidase in thick ascending limb of Henle's loop in rat kidney. American journal of physiology. Renal physiology 20020601
Diphenyleneiodonium triggers the efflux of glutathione from cultured cells. The Journal of biological chemistry 20020531
Gene transfer of Cu/Zn SOD to cerebral vessels prevents FPI-induced CBF autoregulatory dysfunction. American journal of physiology. Heart and circulatory physiology 20020501
Protein overload-induced NF-kappaB activation in proximal tubular cells requires H(2)O(2) through a PKC-dependent pathway. Journal of the American Society of Nephrology : JASN 20020501
Lysophosphatidylcholine activates extracellular signal-regulated kinases 1/2 through reactive oxygen species in rat vascular smooth muscle cells. Arteriosclerosis, thrombosis, and vascular biology 20020501
NADPH oxidase promotes NF-kappaB activation and proliferation in human airway smooth muscle. American journal of physiology. Lung cellular and molecular physiology 20020401
Role of mitochondrial oxidant generation in endothelial cell responses to hypoxia. Arteriosclerosis, thrombosis, and vascular biology 20020401
Effect of homocysteine on arachidonic acid release in human platelets. European journal of clinical investigation 20020401
Blockade of superoxide generation prevents high-affinity immunoglobulin E receptor-mediated release of allergic mediators by rat mast cell line and human basophils. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20020401
Mechanisms of oxygen sensing in human trophoblast cells. Placenta 20020401
Rat liver microsomal and nuclear activation of methanol to hydroxymethyl free radicals. Toxicology letters 20020328
Lysophosphatidylcholine is a major contributor to the synergistic effect of mildly oxidized low-density lipoprotein with endothelin-1 on vascular smooth muscle cell proliferation. Journal of cardiovascular pharmacology 20020301
Hydrogen peroxide is required for poly(phenolic) domain formation during wound-induced suberization. Journal of agricultural and food chemistry 20020227
Effect of a high-salt diet on oxidant enzyme activity in skeletal muscle microcirculation. American journal of physiology. Heart and circulatory physiology 20020201
Preferential inhibition of the plasma membrane NADH oxidase (NOX) activity by diphenyleneiodonium chloride with NADPH as donor. Antioxidants & redox signaling 20020201
Inhibition of NADH/NADPH oxidase affects signal transduction by growth factor receptors in normal fibroblasts. Archives of biochemistry and biophysics 20020115
Modification of 5-hydroxytryptophan-evoked 5-hydroxytryptamine formation of guinea pig colonic mucosa by reactive oxygen species. Japanese journal of pharmacology 20020101
Correlation between NADPH oxidase and protein kinase C in the ROS production by human granulocytes related to age. Gerontology 20020101
Hydrogen peroxide generated during cellular insulin stimulation is integral to activation of the distal insulin signaling cascade in 3T3-L1 adipocytes. The Journal of biological chemistry 20011228
Differential NADPH- versus NADH-dependent superoxide production by phagocyte-type endothelial cell NADPH oxidase. Cardiovascular research 20011201
6-formylpterin intracellularly generates hydrogen peroxide and restores the impaired bactericidal activity of human neutrophils. Biochemical and biophysical research communications 20011123
Role of reactive oxygen intermediates in Japanese encephalitis virus infection in murine neuroblastoma cells. Neuroscience letters 20011123
Direct and indirect bacterial killing functions of neutrophil defensins in lung explants. American journal of physiology. Lung cellular and molecular physiology 20011101
Analysis of reactive oxygen species generating systems in rat epididymal spermatozoa. Biology of reproduction 20011001
A real-time electrochemical technique for measurement of cellular hydrogen peroxide generation and consumption: evaluation in human polymorphonuclear leukocytes. Free radical biology & medicine 20011001
TGF-beta-induced p38 activation is mediated by Rac1-regulated generation of reactive oxygen species in cultured human keratinocytes. International journal of molecular medicine 20010901
Overexpression of manganese superoxide dismutase suppresses increases in collagen accumulation induced by culture of mesangial cells in high-media glucose. Metabolism: clinical and experimental 20010901
K+ channels inhibited by hydrogen peroxide mediate abscisic acid signaling in Vicia guard cells. Cell research 20010901
Hydrogen peroxide is involved in abscisic acid-induced stomatal closure in Vicia faba. Plant physiology 20010801
Diphenyleneiodonium inhibits NF-kappaB activation and iNOS expression induced by IL-1beta: involvement of reactive oxygen species. Mediators of inflammation 20010801
Regulation of angiotensin II-stimulated osteopontin expression in cardiac microvascular endothelial cells: role of p42/44 mitogen-activated protein kinase and reactive oxygen species. Journal of cellular physiology 20010701
Metabolism of S-nitrosoglutathione by endothelial cells. American journal of physiology. Heart and circulatory physiology 20010701
Model for hypoxic pulmonary vasoconstriction involving mitochondrial oxygen sensing. Circulation research 20010622
A novel method for detecting single glandular intestinal metaplasia in the mucosal surface of the fixed stomach using methylene blue. Japanese journal of cancer research : Gann 20010601
The lipopolysaccharides of the phytopathogen Xanthomonas campestris pv. campestris induce an oxidative burst reaction in cell cultures of Nicotiana tabacum. Planta 20010601
NADPH oxidase does not account fully for O2-sensing in model airway chemoreceptor cells. Biochemical and biophysical research communications 20010525
Thrombin regulates insulin-like growth factor-1 receptor transcription in vascular smooth muscle: characterization of the signaling pathway. Circulation research 20010525
Oxidative stress and lipid retention in vascular grafts: comparison between venous and arterial conduits. Circulation 20010515
Diphenyleneiodonium sulfate, an NADPH oxidase inhibitor, prevents early alcohol-induced liver injury in the rat. American journal of physiology. Gastrointestinal and liver physiology 20010501
Antioxidants inhibit JNK and p38 MAPK activation but not ERK 1/2 activation by angiotensin II in rat aortic smooth muscle cells. Hypertension research : official journal of the Japanese Society of Hypertension 20010501
Characterization of the flavoprotein domain of gp91phox which has NADPH diaphorase activity. Journal of biochemistry 20010401
Epidermal growth factor receptor transactivation by angiotensin II requires reactive oxygen species in vascular smooth muscle cells. Arteriosclerosis, thrombosis, and vascular biology 20010401
Enhanced superoxide anion formation in vascular tissues from spontaneously hypertensive and desoxycorticosterone acetate-salt hypertensive rats. Journal of hypertension 20010401
Elevated superoxide production by active H-ras enhances human lung WI-38VA-13 cell proliferation, migration and resistance to TNF-alpha. Oncogene 20010322
Vascular NAD(P)H oxidase is distinct from the phagocytic enzyme and modulates vascular reactivity control. American journal of physiology. Heart and circulatory physiology 20010201
Dual effect of oxidized LDL on cell cycle in human endothelial cells through oxidative stress. Kidney international. Supplement 20010201
Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction. Hypertension (Dallas, Tex. : 1979) 20010201
Characterization of the intramolecular electron transfer pathway from 2-hydroxyphenazine to the heterodisulfide reductase from Methanosarcina thermophila. The Journal of biological chemistry 20010126
Oxygen radical generation and expression of NADPH oxidase genes in bottlenose dolphin (Tursiops truncatus) neutrophils. Developmental and comparative immunology 20010101
Involvement of reactive oxygen species in the induction of (S)-N-p-coumaroyloctopamine accumulation by beta-1,3-glucooligosaccharide elicitors in potato tuber tissues. Zeitschrift fur Naturforschung. C, Journal of biosciences 20010101
[Distribution of rat embryonal fibroblasts through cell cycle phases in the presence of inhibitors of active oxygen species formation and N-acetylcysteine]. Tsitologiia 20010101
Role of extracellular peroxidase in the superoxide production by wheat root cells. Protoplasma 20010101
Hypoxia-inducible angiopoietin-2 expression is mimicked by iodonium compounds and occurs in the rat brain and skin in response to systemic hypoxia and tissue ischemia. The American journal of pathology 20000601
Hypoxic upregulation of tyrosine hydroxylase gene expression is paralleled, but not induced, by increased generation of reactive oxygen species in PC12 cells. FEBS letters 19990820
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