Staurosporine
| Title | Journal |
|---|---|
| The synthetic cannabinoid XLR-11 induces in vitro nephrotoxicity by impairment of endocannabinoid-mediated regulation of mitochondrial function homeostasis and triggering of apoptosis. | Toxicology letters 20180501 |
| Structure-dependent induction of apoptosis by hepatotoxic pyrrolizidine alkaloids in the human hepatoma cell line HepaRG: Single versus repeated exposure. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20180401 |
| t-BuOOH induces ferroptosis in human and murine cell lines. | Archives of toxicology 20180201 |
| Nitroxide Tempol down-regulates kinase activities associated with NADPH oxidase function in phagocytic cells and potentially decreases their fungicidal response. | Chemico-biological interactions 20180105 |
| Sulfide Toxicity and Its Modulation by Nitric Oxide in Bovine Pulmonary Artery Endothelial Cells. | Chemical research in toxicology 20171218 |
| Inhibition of monoamine oxidase-B by selegiline reduces cigarette smoke-induced oxidative stress and inflammation in airway epithelial cells. | Toxicology letters 20170215 |
| Increased SUMO-2/3-ylation mediated by SENP3 degradation is protective against cadmium-induced caspase 3-dependent cytotoxicity. | The Journal of toxicological sciences 20170101 |
| 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure influence the expression of glutamate transporter GLT-1 in C6 glioma cells via the Ca(2+) /protein kinase C pathway. | Journal of applied toxicology : JAT 20161101 |
| Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer. | Cancer letters 20161028 |
| AhR-dependent 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity in human neuronal cell line SHSY5Y. | Neurotoxicology 20160901 |
| Efficacy and Safety of Midostaurin in Advanced Systemic Mastocytosis. | The New England journal of medicine 20160630 |
| Tracking micro-optical resonances for identifying and sensing novel procaspase-3 protein marker released from cell cultures in response to toxins. | Nanotechnology 20160422 |
| Ginkgolide B protects human umbilical vein endothelial cells against xenobiotic injuries via PXR activation. | Acta pharmacologica Sinica 20160201 |
| An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death. | The Journal of biological chemistry 20150821 |
| Utilization of human nuclear receptors as an early counter screen for off-target activity: a case study with a compendium of 615 known drugs. | Toxicological sciences : an official journal of the Society of Toxicology 20150601 |
| The bipartite rac1 Guanine nucleotide exchange factor engulfment and cell motility 1/dedicator of cytokinesis 180 (elmo1/dock180) protects endothelial cells from apoptosis in blood vessel development. | The Journal of biological chemistry 20150306 |
| Manganese superoxide dismutase knock-down in 3T3-L1 preadipocytes impairs subsequent adipogenesis. | Molecular and cellular biochemistry 20140801 |
| Critical differences in toxicity mechanisms in induced pluripotent stem cell-derived hepatocytes, hepatic cell lines and primary hepatocytes. | Archives of toxicology 20140701 |
| Testosterone induces apoptosis in vascular smooth muscle cells via extrinsic apoptotic pathway with mitochondria-generated reactive oxygen species involvement. | American journal of physiology. Heart and circulatory physiology 20140601 |
| Discovery of N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-fluoroaniline (EW-7197): a highly potent, selective, and orally bioavailable inhibitor of TGF-β type I receptor kinase as cancer immunotherapeutic/antifibrotic agent. | Journal of medicinal chemistry 20140522 |
| Activation of peroxisome proliferator-activated receptor-β/δ (PPAR-β/δ) inhibits human breast cancer cell line tumorigenicity. | Molecular cancer therapeutics 20140401 |
| Nicotine decreases the activity of glutamate transporter type 3. | Toxicology letters 20140210 |
| Anti-neuroinflammatory efficacy of the aldose reductase inhibitor FMHM via phospholipase C/protein kinase C-dependent NF-κB and MAPK pathways. | Toxicology and applied pharmacology 20131115 |
| A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. | Toxicological sciences : an official journal of the Society of Toxicology 20131101 |
| Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3. | Journal of medicinal chemistry 20131024 |
| Progesterone increases the activity of glutamate transporter type 3 expressed in Xenopus oocytes. | European journal of pharmacology 20130905 |
| Aneugenic potential of the anticancer drugs melphalan and chlorambucil. The involvement of apoptosis and chromosome segregation regulating proteins. | Journal of applied toxicology : JAT 20130701 |
| The development of CNS-active LRRK2 inhibitors using property-directed optimisation. | Bioorganic & medicinal chemistry letters 20130701 |
| A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery. | The Biochemical journal 20130415 |
| Caffeine-induced inhibition of the activity of glutamate transporter type 3 expressed in Xenopus oocytes. | Toxicology letters 20130227 |
| Comparative structural and functional studies of 4-(thiazol-5-yl)-2-(phenylamino)pyrimidine-5-carbonitrile CDK9 inhibitors suggest the basis for isotype selectivity. | Journal of medicinal chemistry 20130214 |
| Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors. | Bioorganic & medicinal chemistry letters 20130115 |
| Matching biochemical and functional efficacies confirm ZIP as a potent competitive inhibitor of PKMζ in neurons. | Neuropharmacology 20130101 |
| Lead induces similar gene expression changes in brains of gestationally exposed adult mice and in neurons differentiated from mouse embryonic stem cells. | PloS one 20130101 |
| Detection of apoptosis through the lipid order of the outer plasma membrane leaflet. | Biochimica et biophysica acta 20121201 |
| O-Aryl α,β-d-ribofuranosides: synthesis & highly efficient biocatalytic separation of anomers and evaluation of their Src kinase inhibitory activity. | Bioorganic & medicinal chemistry 20121201 |
| Small-molecule screen identifies modulators of EWS/FLI1 target gene expression and cell survival in Ewing's sarcoma. | International journal of cancer 20121101 |
| Senescence determines the fate of activated rat pancreatic stellate cells. | Journal of cellular and molecular medicine 20121101 |
| The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production. | Cell death and differentiation 20121101 |
| SIRT3 protects from hypoxia and staurosporine-mediated cell death by maintaining mitochondrial membrane potential and intracellular pH. | Cell death and differentiation 20121101 |
| Over-expression of HSP70 attenuates caspase-dependent and caspase-independent pathways and inhibits neuronal apoptosis. | Journal of neurochemistry 20121101 |
| 2,3,7,8-Tetrachlorodibenzo-p-dioxin induces apoptosis by disruption of intracellular calcium homeostasis in human neuronal cell line SHSY5Y. | Apoptosis : an international journal on programmed cell death 20121101 |
| Design, synthesis and biological evaluation of heterocyclic azoles derivatives containing pyrazine moiety as potential telomerase inhibitors. | Bioorganic & medicinal chemistry 20121101 |
| Overexpression of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase A in nerve cells confers resistance to amyloid β and other toxins by decreasing mitochondrial respiration and reactive oxygen species production. | The Journal of biological chemistry 20121026 |
| Induced pluripotent stem cell models of progranulin-deficient frontotemporal dementia uncover specific reversible neuronal defects. | Cell reports 20121025 |
| Nonoisotopic assay for the presynaptic choline transporter reveals capacity for allosteric modulation of choline uptake. | ACS chemical neuroscience 20121017 |
| Chronic restraint stress aggravated arthritic joint swell of rats through regulating nitric oxide production. | Nitric oxide : biology and chemistry 20121015 |
| Molecular design, synthesis, and evaluation of novel potent apoptosis inhibitors inspired from bongkrekic acid. | Chemical research in toxicology 20121015 |
| Staurosporine induces apoptosis and necroptosis in cultured rat astrocytes. | Drug and chemical toxicology 20121001 |
| Using combination therapy to override stromal-mediated chemoresistance in mutant FLT3-positive AML: synergism between FLT3 inhibitors, dasatinib/multi-targeted inhibitors and JAK inhibitors. | Leukemia 20121001 |
| Detecting the effect of targeted anti-cancer medicines on single cancer cells using a poly-silicon wire ion sensor integrated with a confined sensitive window. | Biomedical microdevices 20121001 |
| Axin expression reduces staurosporine-induced mitochondria-mediated cell death in HeLa cells. | Experimental cell research 20121001 |
| Expression of the hyperphosphorylated tau attenuates ER stress-induced apoptosis with upregulation of unfolded protein response. | Apoptosis : an international journal on programmed cell death 20121001 |
| Apoptosis-inducing effects of distichamine and narciprimine, rare alkaloids of the plant family Amaryllidaceae. | Bioorganic & medicinal chemistry letters 20121001 |
| MicroR828 regulates lignin and H2O2 accumulation in sweet potato on wounding. | The New phytologist 20121001 |
| Curcumin protects against staurosporine toxicity in rat neurons. | Neuroscience bulletin 20121001 |
| Staurosporine and cytochalasin D induce chondrogenesis by regulation of actin dynamics in different way. | Experimental & molecular medicine 20120930 |
| Bcl-x pre-mRNA splicing regulates brain injury after neonatal hypoxia-ischemia. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20120926 |
| A novel approach to the discovery of small-molecule ligands of CDK2. | Chembiochem : a European journal of chemical biology 20120924 |
| Neuroprotective effect of alpha-lipoic acid on hydrostatic pressure-induced damage of retinal ganglion cells in vitro. | Neuroscience letters 20120920 |
| Spatially selective reagent delivery into cancer cells using a two-layer microfluidic culture system. | Analytica chimica acta 20120919 |
| Jedi-1 and MEGF10 signal engulfment of apoptotic neurons through the tyrosine kinase Syk. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20120919 |
| Protective effects of 27- and 24-hydroxycholesterol against staurosporine-induced cell death in undifferentiated neuroblastoma SH-SY5Y cells. | Neuroscience letters 20120906 |
| Hyperglycemia induced down-regulation of renal P-glycoprotein expression. | European journal of pharmacology 20120905 |
| The APP intracellular domain (AICD) potentiates ER stress-induced apoptosis. | Neurobiology of aging 20120901 |
| Src tyrosine kinase inhibits apoptosis through the Erk1/2- dependent degradation of the death accelerator Bik. | Cell death and differentiation 20120901 |
| Network analysis of icb-1 gene function in human breast cancer cells. | Journal of cellular biochemistry 20120901 |
| Phase IB study of the FLT3 kinase inhibitor midostaurin with chemotherapy in younger newly diagnosed adult patients with acute myeloid leukemia. | Leukemia 20120901 |
| Differential effects of the glycolysis inhibitor 2-deoxy-D-glucose on the activity of pro-apoptotic agents in metastatic melanoma cells, and induction of a cytoprotective autophagic response. | International journal of cancer 20120815 |
| Mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2) as an antiinflammatory target: discovery and in vivo activity of selective pyrazolo[1,5-a]pyrimidine inhibitors using a focused library and structure-based optimization approach. | Journal of medicinal chemistry 20120809 |
| Predicting new indications for approved drugs using a proteochemometric method. | Journal of medicinal chemistry 20120809 |
| Mood stabilizers commonly restore staurosporine-induced increase of p53 expression and following decrease of Bcl-2 expression in SH-SY5Y cells. | Progress in neuro-psychopharmacology & biological psychiatry 20120807 |
| The role of COX-2/PGE2 in gossypol-induced apoptosis of colorectal carcinoma cells. | Journal of cellular physiology 20120801 |
| Staurosporine-induced differentiation of the RGC-5 cell line leads to apoptosis and cell death at the lowest differentiating concentration. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20120801 |
| The non-genomic rapid acidification in peripheral T cells by progesterone depends on intracellular calcium increase and not on Na+/H+-exchange inhibition. | Steroids 20120801 |
| Early-phase occurrence of K+ and Cl- efflux in addition to Ca 2+ mobilization is a prerequisite to apoptosis in HeLa cells. | Apoptosis : an international journal on programmed cell death 20120801 |
| Type 1 inositol-1,4,5-trisphosphate receptor is a late substrate of caspases during apoptosis. | Journal of cellular biochemistry 20120801 |
| Individual dose and scheduling determine the efficacy of combining cytotoxic anticancer agents with a kinase inhibitor in non-small-cell lung cancer. | Journal of cancer research and clinical oncology 20120801 |
| Effects of pregabalin on the activity of glutamate transporter type 3. | British journal of anaesthesia 20120801 |
| Modulation of purinergic neuromuscular transmission by phorbol dibutyrate is independent of protein kinase C in murine urinary bladder. | The Journal of pharmacology and experimental therapeutics 20120801 |
| Neurotrophic actions initiated by proNGF in adult sensory neurons may require peri-somatic glia to drive local cleavage to NGF. | Journal of neurochemistry 20120801 |
| Monitoring autophagic flux by an improved tandem fluorescent-tagged LC3 (mTagRFP-mWasabi-LC3) reveals that high-dose rapamycin impairs autophagic flux in cancer cells. | Autophagy 20120801 |
| The antiapoptotic effect of galectin-3 in human endometrial cells under the regulation of estrogen and progesterone. | Biology of reproduction 20120801 |
| Withaferin A-related steroids from Withania aristata exhibit potent antiproliferative activity by inducing apoptosis in human tumor cells. | European journal of medicinal chemistry 20120801 |
| Protease-activated receptor-1 cleaved at R46 mediates cytoprotective effects. | Journal of thrombosis and haemostasis : JTH 20120801 |
| Suppression of hydatidiform molar growth by inhibiting endogenous brain-derived neurotrophic factor/tyrosine kinase B signaling. | Endocrinology 20120801 |
| The protective roles of phosphorylated heat shock protein 27 in human cells harboring myoclonus epilepsy with ragged-red fibers A8344G mtDNA mutation. | The FEBS journal 20120801 |
| Implication of multiple signaling pathways in the regulation of angiotensin II induced enhanced expression of Giα proteins in vascular smooth muscle cells. | Canadian journal of physiology and pharmacology 20120801 |
| Long-term administration of amnion-derived cellular cytokine suspension promotes functional recovery in a model of penetrating ballistic-like brain injury. | The journal of trauma and acute care surgery 20120801 |
| An unusual role for a mobile flavin in StaC-like indolocarbazole biosynthetic enzymes. | Chemistry & biology 20120727 |
| Possible role of brain salt-inducible kinase 1 in responses to central sodium in Dahl rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20120715 |
| Human immunodeficiency virus type 1 alters brain-derived neurotrophic factor processing in neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20120711 |
| Methylene blue protects primary rat retinal ganglion cells from cellular senescence. | Investigative ophthalmology & visual science 20120710 |
| ATP depletion triggers acute myeloid leukemia differentiation through an ATR/Chk1 protein-dependent and p53 protein-independent pathway. | The Journal of biological chemistry 20120706 |
| Ciliogenic RFX transcription factors regulate FGF1 gene promoter. | Journal of cellular biochemistry 20120701 |
| Celecoxib enhances the radiosensitizing effect of 7-hydroxystaurosporine (UCN-01) in human lung cancer cell lines. | International journal of radiation oncology, biology, physics 20120701 |
| Insulin-like growth factor-II and heparin are anti-apoptotic survival factors in human villous cytotrophoblast. | European journal of obstetrics, gynecology, and reproductive biology 20120701 |
| Protein kinase C stimulates human B cell activating factor gene expression through reactive oxygen species-dependent c-Fos in THP-1 pro-monocytic cells. | Cytokine 20120701 |
| Extracellular matrix proteoglycan plays a pivotal role in sensitization by low pH of mechanosensitive currents in nociceptive sensory neurones. | The Journal of physiology 20120701 |
| Mild activation of poly(ADP-ribose) polymerase (PARP) is neuroprotective in rat hippocampal slice models of ischemic tolerance. | The European journal of neuroscience 20120701 |
| CCR3 induced-p42/44 MAPK activation protects against staurosporine induced-DNA fragmentation but not apoptosis in airway smooth muscle cells. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20120701 |
| Differential expression of BNIP family members of BH3-only proteins during the development and after axotomy in the rat. | Molecules and cells 20120630 |
| Staurosporine induces ganglion cell differentiation in part by stimulating urokinase-type plasminogen activator expression and activation in the developing chick retina. | Biochemical and biophysical research communications 20120622 |
| Tunicamycin produces TDP-43 cytoplasmic inclusions in cultured brain organotypic slices. | Journal of the neurological sciences 20120615 |
| ADF/cofilin proteins translocate to mitochondria during apoptosis but are not generally required for cell death signaling. | Cell death and differentiation 20120601 |
| Apoptotic effect of different self-etch dental adhesives on odontoblasts in cell cultures. | Archives of oral biology 20120601 |
| Systems kinomics demonstrates Congo Basin monkeypox virus infection selectively modulates host cell signaling responses as compared to West African monkeypox virus. | Molecular & cellular proteomics : MCP 20120601 |
| Cell death, non-invasively assessed by intrinsic fluorescence intensity of NADH, is a predictive indicator of functional differentiation of embryonic stem cells. | Biology of the cell 20120601 |
| Cell volume changes during apoptosis monitored in real time using digital holographic microscopy. | Journal of structural biology 20120601 |
| Synthesis, biological evaluation and molecular docking studies of novel 2-(1,3,4-oxadiazol-2-ylthio)-1-phenylethanone derivatives. | Bioorganic & medicinal chemistry 20120601 |
| Pathogen-mediated proteolysis of the cell death regulator RIPK1 and the host defense modulator RIPK2 in human aortic endothelial cells. | PLoS pathogens 20120601 |
| Nuclear transfer with apoptotic bovine fibroblasts: can programmed cell death be reprogrammed? | Cellular reprogramming 20120601 |
| Tissue inhibitor of metalloproteinases-1 protects human neurons from staurosporine and HIV-1-induced apoptosis: mechanisms and relevance to HIV-1-associated dementia. | Cell death & disease 20120601 |
| Quiescence and γH2AX in neuroblastoma are regulated by ouabain/Na,K-ATPase. | British journal of cancer 20120522 |
| The CDK9 C-helix exhibits conformational plasticity that may explain the selectivity of CAN508. | ACS chemical biology 20120518 |
| Kinase-dependent activation of voltage-gated Ca2+ channels by ET-1 in pulmonary arterial myocytes during chronic hypoxia. | American journal of physiology. Lung cellular and molecular physiology 20120515 |
| Six-transmembrane topology for Golgi anti-apoptotic protein (GAAP) and Bax inhibitor 1 (BI-1) provides model for the transmembrane Bax inhibitor-containing motif (TMBIM) family. | The Journal of biological chemistry 20120504 |
| Influenza induces endoplasmic reticulum stress, caspase-12-dependent apoptosis, and c-Jun N-terminal kinase-mediated transforming growth factor-β release in lung epithelial cells. | American journal of respiratory cell and molecular biology 20120501 |
| AMIGO is expressed in multiple brain cell types and may regulate dendritic growth and neuronal survival. | Journal of cellular physiology 20120501 |
| Unfolded protein response is not activated in the mucopolysaccharidoses but protein disulfide isomerase 5 is deregulated. | Journal of inherited metabolic disease 20120501 |
| An adaptation of the human HepaRG cells to the in vitro micronucleus assay. | Mutagenesis 20120501 |
| Carboxyl-terminal modulator protein induces apoptosis by regulating mitochondrial function in lung cancer cells. | International journal of oncology 20120501 |
| Swelling rather than shrinkage precedes apoptosis in serum-deprived vascular smooth muscle cells. | Apoptosis : an international journal on programmed cell death 20120501 |
| Midostaurin does not prolong cardiac repolarization defined in a thorough electrocardiogram trial in healthy volunteers. | Cancer chemotherapy and pharmacology 20120501 |
| Activation of protein kinase A and C prevents recovery from persistent depolarization produced by oxygen and glucose deprivation in rat hippocampal neurons. | Journal of neurophysiology 20120501 |
| Downregulation of vasopressin V1A receptors and activation of mitogen-activated protein kinase in rat mesangial cells cultured under high-glucose conditions. | Clinical and experimental pharmacology & physiology 20120501 |
| Pomegranate juice and punicalagin attenuate oxidative stress and apoptosis in human placenta and in human placental trophoblasts. | American journal of physiology. Endocrinology and metabolism 20120501 |
| Specific phosphorylation of αA-crystallin is required for the αA-crystallin-induced protection of astrocytes against staurosporine and C2-ceramide toxicity. | Neurochemistry international 20120501 |
| Synthesis, biological evaluation, and molecular docking studies of 1,3,4-thiadiazol-2-amide derivatives as novel anticancer agents. | Bioorganic & medicinal chemistry 20120501 |
| Inhibition of Eg5 acts synergistically with checkpoint abrogation in promoting mitotic catastrophe. | Molecular cancer research : MCR 20120501 |
| Protective effect of sauchinone against regional myocardial ischemia/reperfusion injury: inhibition of p38 MAPK and JNK death signaling pathways. | Journal of Korean medical science 20120501 |
| Role of keratinocytes in the development of vitiligo. | Annals of dermatology 20120501 |
| p57(KIP2) control of actin cytoskeleton dynamics is responsible for its mitochondrial pro-apoptotic effect. | Cell death & disease 20120501 |
| [Influence of Erigeron breviscapus on the expression of collagen type I , MMP1 and TIMP1 of MRC-5 cells under hypoxia]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20120501 |
| Structure elucidation and anticancer activity of 7-oxostaurosporine derivatives from the Brazilian endemic tunicate Eudistoma vannamei. | Marine drugs 20120501 |
| [Involvement of protein kinase C in enhancement of vascular calcium sensitivity by blocking mesenteric lymph return in hemorrhagic shock rats]. | Sheng li xue bao : [Acta physiologica Sinica] 20120425 |
| Site-specific synapsin I phosphorylation participates in the expression of post-tetanic potentiation and its enhancement by BDNF. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20120425 |
| Detection of asymmetric distribution of phospholipids by fluorescence resonance energy transfer. | Biochemical and biophysical research communications 20120420 |
| Expression of a truncated active form of VDAC1 in lung cancer associates with hypoxic cell survival and correlates with progression to chemotherapy resistance. | Cancer research 20120415 |
| Cellular pharmacology of protein kinase Mζ (PKMζ) contrasts with its in vitro profile: implications for PKMζ as a mediator of memory. | The Journal of biological chemistry 20120413 |
| Synthesis of novel 6-(4-substituted piperazine-1-yl)-9-(β-D-ribofuranosyl)purine derivatives, which lead to senescence-induced cell death in liver cancer cells. | Journal of medicinal chemistry 20120412 |
| Chk'ing p53-deficient breast cancers. | The Journal of clinical investigation 20120402 |
| Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models. | The Journal of clinical investigation 20120402 |
| Neuroprotection of kaempferol by autophagy in models of rotenone-mediated acute toxicity: possible implications for Parkinson's disease. | Neurobiology of aging 20120401 |
| A phase II study of cell cycle inhibitor UCN-01 in patients with metastatic melanoma: a California Cancer Consortium trial. | Investigational new drugs 20120401 |
| Factors influencing the inhibition of protein kinases. | Journal of enzyme inhibition and medicinal chemistry 20120401 |
| Profilin1 facilitates staurosporine-triggered apoptosis by stabilizing the integrin β1-actin complex in breast cancer cells. | Journal of cellular and molecular medicine 20120401 |
| Interaction between NH(2)-tau fragment and Aβ in Alzheimer's disease mitochondria contributes to the synaptic deterioration. | Neurobiology of aging 20120401 |
| A unique library of myogenic cells from facioscapulohumeral muscular dystrophy subjects and unaffected relatives: family, disease and cell function. | European journal of human genetics : EJHG 20120401 |
| Apoptotic cell-derived ICAM-3 promotes both macrophage chemoattraction to and tethering of apoptotic cells. | Cell death and differentiation 20120401 |
| Minimally modified LDL upregulates endothelin type B receptors in rat coronary artery via ERK1/2 MAPK and NF-κB pathways. | Biochimica et biophysica acta 20120401 |
| Protease activation and the signal transduction pathway regulating motility in sperm from the water strider Aquarius remigis. | Cytoskeleton (Hoboken, N.J.) 20120401 |
| Nerve growth factor-mediated neuronal plasticity in spinal cord contributes to neonatal maternal separation-induced visceral hypersensitivity in rats. | European journal of pain (London, England) 20120401 |
| Systemic mastocytosis in adults: 2012 Update on diagnosis, risk stratification, and management. | American journal of hematology 20120401 |
| Protective effect of grape seed extract against oxidative stress-induced cell death in a staurosporine-differentiated retinal ganglion cell line. | Current eye research 20120401 |
| Molecular targeted therapy in acute myeloid leukemia. | Hematology (Amsterdam, Netherlands) 20120401 |
| The mitochondrial ATPase inhibitory factor 1 triggers a ROS-mediated retrograde prosurvival and proliferative response. | Molecular cell 20120330 |
| Scythe cleavage during Fas (APO-1)-and staurosporine-mediated apoptosis. | FEBS letters 20120323 |
| GILZ inhibits the mTORC2/AKT pathway in BCR-ABL(+) cells. | Oncogene 20120315 |
| A novel non-canonical mechanism of regulation of MST3 (mammalian Sterile20-related kinase 3). | The Biochemical journal 20120315 |
| Apoptotic DNA degradation into oligonucleosomal fragments, but not apoptotic nuclear morphology, relies on a cytosolic pool of DFF40/CAD endonuclease. | The Journal of biological chemistry 20120302 |
| Ceramide 1-phosphate stimulates proliferation of C2C12 myoblasts. | Biochimie 20120301 |
| Off-target immune cell toxicity caused by AG-012986, a pan-CDK inhibitor, is associated with inhibition of p38 MAPK phosphorylation. | Journal of biochemical and molecular toxicology 20120301 |
| Metformin differentially activates ER stress signaling pathways without inducing apoptosis. | Disease models & mechanisms 20120301 |
| Desensitization and trafficking of μ-opioid receptors in locus ceruleus neurons: modulation by kinases. | Molecular pharmacology 20120301 |
| ATR-Chk1 signaling pathway and homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity. | DNA repair 20120301 |
| Evaluation of apoptosis induced by nanoparticles and fine particles in RAW 264.7 macrophages: facts and artefacts. | Toxicology in vitro : an international journal published in association with BIBRA 20120301 |
| Minimally modified LDL upregulates endothelin type B receptors in rat basilar artery. | Microvascular research 20120301 |
| Cross talk among calcium, hydrogen peroxide, and nitric oxide and activation of gene expression involving calmodulins and calcium-dependent protein kinases in Ulva compressa exposed to copper excess. | Plant physiology 20120301 |
| Targeting sphingosine kinase-1 to inhibit melanoma. | Pigment cell & melanoma research 20120301 |
| FTS and 2-DG induce pancreatic cancer cell death and tumor shrinkage in mice. | Cell death & disease 20120301 |
| Anti-apoptotic effects of SERPIN B3 and B4 via STAT6 activation in macrophages after infection with Toxoplasma gondii. | The Korean journal of parasitology 20120301 |
| Igf1r signaling is indispensable for preimplantation development and is activated via a novel function of E-cadherin. | PLoS genetics 20120301 |
| The Role of NLR-related Protein 3 Inflammasome in Host Defense and Inflammatory Diseases. | International neurourology journal 20120301 |
| Curcumin affects cell survival and cell volume regulation in human renal and intestinal cells. | Toxicology 20120226 |
| 17β-Estradiol attenuates the activity of the glutamate transporter type 3 expressed in Xenopus oocytes. | European journal of pharmacology 20120215 |
| Tetracyclines convert the osteoclastic-differentiation pathway of progenitor cells to produce dendritic cell-like cells. | Journal of immunology (Baltimore, Md. : 1950) 20120215 |
| α-Secretase-derived fragment of cellular prion, N1, protects against monomeric and oligomeric amyloid β (Aβ)-associated cell death. | The Journal of biological chemistry 20120210 |
| KIT with D816 mutations cooperates with CBFB-MYH11 for leukemogenesis in mice. | Blood 20120209 |
| A digital microfluidic method for multiplexed cell-based apoptosis assays. | Lab on a chip 20120207 |
| K252a induces anoikis-sensitization with suppression of cellular migration in Epstein-Barr virus (EBV)--associated nasopharyngeal carcinoma cells. | Investigational new drugs 20120201 |
| Cannabinoid WIN 55,212-2 inhibits TRPV1 in trigeminal ganglion neurons via PKA and PKC pathways. | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20120201 |
| Selective regulation of IP3-receptor-mediated Ca2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl. | Cell death and differentiation 20120201 |
| Pancreatic β-cell prosurvival effects of the incretin hormones involve post-translational modification of Kv2.1 delayed rectifier channels. | Cell death and differentiation 20120201 |
| Early apoptotic reorganization of spliceosomal proteins involves caspases, CAD and rearrangement of NuMA. | Traffic (Copenhagen, Denmark) 20120201 |
| Assessment of compound hepatotoxicity using human plateable cryopreserved hepatocytes in a 1536-well-plate format. | Assay and drug development technologies 20120201 |
| Synthesis and biological evaluation of novel indolocarbazoles with anti-angiogenic activity. | European journal of medicinal chemistry 20120201 |
| Preclinical development of the novel Chk1 inhibitor SCH900776 in combination with DNA-damaging agents and antimetabolites. | Molecular cancer therapeutics 20120201 |
| Defective cell death signalling along the Bcl-2 regulated apoptosis pathway compromises Treg cell development and limits their functionality in mice. | Journal of autoimmunity 20120201 |
| GSK3β regulates Bcl2L12 and Bcl2L12A anti-apoptosis signaling in glioblastoma and is inhibited by LiCl. | Cell cycle (Georgetown, Tex.) 20120201 |
| Correlating light scattering with internal cellular structures. | Biomedical optics express 20120201 |
| Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death. | PLoS pathogens 20120201 |
| Possible involvement of calcium channels and plasma membrane receptors on Staurosporine-induced neurite outgrowth. | Bosnian journal of basic medical sciences 20120201 |
| Targeting Mnks for cancer therapy. | Oncotarget 20120201 |
| γ-Secretase-dependent cleavage of E-cadherin by staurosporine in breast cancer cells. | Cell communication & adhesion 20120201 |
| Protein kinase domain of CTR1 from Arabidopsis thaliana promotes ethylene receptor cross talk. | Journal of molecular biology 20120127 |
| Reusable amperometric biosensor for measuring protein tyrosine kinase activity. | Analytical chemistry 20120117 |
| Neurotoxic injury pathways in differentiated mouse motor neuron-neuroblastoma hybrid (NSC-34D) cells in vitro--limited effect of riluzole on thapsigargin, but not staurosporine, hydrogen peroxide and homocysteine neurotoxicity. | Toxicology and applied pharmacology 20120115 |
| Roles of phosphoinositide-dependent kinase-1 in α1B-adrenoceptor phosphorylation and desensitization. | European journal of pharmacology 20120115 |
| In vitro and in silico studies on substrate recognition and acceptance of human PKMYT1, a Cdk1 inhibitory kinase. | Bioorganic & medicinal chemistry letters 20120115 |
| Pro-nerve growth factor induces autocrine stimulation of breast cancer cell invasion through tropomyosin-related kinase A (TrkA) and sortilin protein. | The Journal of biological chemistry 20120113 |
| Bone morphogenetic protein (BMP)-4 and BMP-7 suppress granulosa cell apoptosis via different pathways: BMP-4 via PI3K/PDK-1/Akt and BMP-7 via PI3K/PDK-1/PKC. | Biochemical and biophysical research communications 20120113 |
| Cold and heat pattern of rheumatoid arthritis in traditional Chinese medicine: distinct molecular signatures indentified by microarray expression profiles in CD4-positive T cell. | Rheumatology international 20120101 |
| In vivo BDNF modulation of hippocampal mossy fiber plasticity induced by high frequency stimulation. | Hippocampus 20120101 |
| Rapid death of duck cells infected with influenza: a potential mechanism for host resistance to H5N1. | Immunology and cell biology 20120101 |
| Traditional chinese medicine for senile dementia. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| Exogenous regucalcin stimulates osteoclastogenesis and suppresses osteoblastogenesis through NF-κB activation. | Molecular and cellular biochemistry 20120101 |
| Characterization of kinase inhibitors using different phosphorylation states of colony stimulating factor-1 receptor tyrosine kinase. | Journal of biochemistry 20120101 |
| GABA(A) receptor blockade enhances memory consolidation by increasing hippocampal BDNF levels. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20120101 |
| Proteome-wide identification of staurosporine-binding kinases using capture compound mass spectrometry. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| Early postnatal exposure of mice to side-steam tobacco smoke increases neuropeptide Y in lung. | American journal of physiology. Lung cellular and molecular physiology 20120101 |
| Hypersensitivity of A8344G MERRF mutated cybrid cells to staurosporine-induced cell death is mediated by calcium-dependent activation of calpains. | The international journal of biochemistry & cell biology 20120101 |
| Determination of kinase inhibitor potencies in cell extracts by competition binding assays and isobaric mass tags. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| Design and combinatorial synthesis of a novel kinase-focused library using click chemistry-based fragment assembly. | Bioorganic & medicinal chemistry letters 20120101 |
| Salt-inducible kinase is involved in the regulation of corticotropin-releasing hormone transcription in hypothalamic neurons in rats. | Endocrinology 20120101 |
| Mitochondrial dysfunction and β-cell failure in type 2 diabetes mellitus. | Experimental diabetes research 20120101 |
| One-pot regioselective synthesis of tetrahydroindazolones and evaluation of their antiproliferative and Src kinase inhibitory activities. | Bioorganic & medicinal chemistry letters 20120101 |
| Effect of activation of canonical Wnt signaling by the Wnt-3a protein on the susceptibility of PC12 cells to oxidative and apoptotic insults. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20120101 |
| Arachidonic acid inhibits Na⁺-K⁺-ATPase via cytochrome P-450, lipoxygenase and protein kinase C-dependent pathways in sheep pulmonary artery. | Vascular pharmacology 20120101 |
| Directed evolution of mammalian anti-apoptosis proteins by somatic hypermutation. | Protein engineering, design & selection : PEDS 20120101 |
| Myocardin-related transcription factor A regulates expression of Bok and Noxa and is involved in apoptotic signalling. | Cell cycle (Georgetown, Tex.) 20120101 |
| Knock down of heat shock protein 27 (HspB1) induces degradation of several putative client proteins. | PloS one 20120101 |
| Legionella pneumophila secretes a mitochondrial carrier protein during infection. | PLoS pathogens 20120101 |
| GW8510 increases insulin expression in pancreatic alpha cells through activation of p53 transcriptional activity. | PloS one 20120101 |
| The interplay between the Escherichia coli Rho guanine nucleotide exchange factor effectors and the mammalian RhoGEF inhibitor EspH. | mBio 20120101 |
| Global analysis of small molecule binding to related protein targets. | PLoS computational biology 20120101 |
| A whole cell assay to measure caspase-6 activity by detecting cleavage of lamin A/C. | PloS one 20120101 |
| α-Secretase-derived cleavage of cellular prion yields biologically active catabolites with distinct functions. | Neuro-degenerative diseases 20120101 |
| Effects of long-term exposure of gelatinated and non-gelatinated cadmium telluride quantum dots on differentiated PC12 cells. | Journal of nanobiotechnology 20120101 |
| Continuous and long-term volume measurements with a commercial Coulter counter. | PloS one 20120101 |
| Amoebal endosymbiont Protochlamydia induces apoptosis to human immortal HEp-2 cells. | PloS one 20120101 |
| Paclitaxel resistance is associated with switch from apoptotic to autophagic cell death in MCF-7 breast cancer cells. | Cell death & disease 20120101 |
| Staurosporine induced poly (ADP-ribose) polymerase independent cell death in Dictyostelium discoideum. | Indian journal of experimental biology 20120101 |
| On Programmed Cell Death in Plasmodium falciparum: Status Quo. | Journal of tropical medicine 20120101 |
| Group B streptococcus GAPDH is released upon cell lysis, associates with bacterial surface, and induces apoptosis in murine macrophages. | PloS one 20120101 |
| Nucleolar localization of GLTSCR2/PICT-1 is mediated by multiple unique nucleolar localization sequences. | PloS one 20120101 |
| Deregulation of apoptosis-related genes is associated with PRV1 overexpression and JAK2 V617F allele burden in Essential Thrombocythemia and Myelofibrosis. | Journal of hematology & oncology 20120101 |
| Coxiella burnetii induces apoptosis during early stage infection via a caspase-independent pathway in human monocytic THP-1 cells. | PloS one 20120101 |
| Early cell death detection with digital holographic microscopy. | PloS one 20120101 |
| Inhibition of post-synaptic Kv7/KCNQ/M channels facilitates long-term potentiation in the hippocampus. | PloS one 20120101 |
| Activation of PKCzeta and PKMzeta in the nucleus accumbens core is necessary for the retrieval, consolidation and reconsolidation of drug memory. | PloS one 20120101 |
| Evidence for conserved function of γ-glutamyltranspeptidase in Helicobacter genus. | PloS one 20120101 |
| Extent of extracellular signal-regulated kinases phosphorylation determines the sensitivity of hepatic stellate cells to staurosporine-induced apoptosis. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20120101 |
| GSK3 as a Sensor Determining Cell Fate in the Brain. | Frontiers in molecular neuroscience 20120101 |
| Role of the neuronal K-Cl co-transporter KCC2 in inhibitory and excitatory neurotransmission. | Frontiers in cellular neuroscience 20120101 |
| Novel protein kinase signaling systems regulating lifespan identified by small molecule library screening using Drosophila. | PloS one 20120101 |
| Matrix-bound PAI-1 supports cell blebbing via RhoA/ROCK1 signaling. | PloS one 20120101 |
| In silico study of fucoxanthin as a tumor cytotoxic agent. | Journal of pharmacy & bioallied sciences 20120101 |
| Radiosensitization by the novel DNA intercalating agent vosaroxin. | Radiation oncology (London, England) 20120101 |
| In vivo monitoring of liver damage using caspase-3 probe. | Theranostics 20120101 |
| FLIM-FRET Imaging of Caspase-3 Activity in Live Cells Using Pair of Red Fluorescent Proteins. | Theranostics 20120101 |
| Protein carbonylation and aggregation precede neuronal apoptosis induced by partial glutathione depletion. | ASN neuro 20120101 |
| Molecular characterization, tissue distribution, subcellular localization and actin-sequestering function of a thymosin protein from silkworm. | PloS one 20120101 |
| Comparative gene expression profiling of P. falciparum malaria parasites exposed to three different histone deacetylase inhibitors. | PloS one 20120101 |
| Exendin-4 ameliorates motor neuron degeneration in cellular and animal models of amyotrophic lateral sclerosis. | PloS one 20120101 |
| Scopolamine administration modulates muscarinic, nicotinic and NMDA receptor systems. | PloS one 20120101 |
| Neutrophil extracellular traps directly induce epithelial and endothelial cell death: a predominant role of histones. | PloS one 20120101 |
| Novel microfilaricidal activity of nanosilver. | International journal of nanomedicine 20120101 |
| Chemotherapeutics and radiation stimulate MHC class I expression through elevated interferon-beta signaling in breast cancer cells. | PloS one 20120101 |
| DNA repair in human pluripotent stem cells is distinct from that in non-pluripotent human cells. | PloS one 20120101 |
| Titanium dioxide induces apoptotic cell death through reactive oxygen species-mediated Fas upregulation and Bax activation. | International journal of nanomedicine 20120101 |
| Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation. | PloS one 20120101 |
| FLASH knockdown sensitizes cells to Fas-mediated apoptosis via down-regulation of the anti-apoptotic proteins, MCL-1 and Cflip short. | PloS one 20120101 |
| Tunneling nanotubes provide a unique conduit for intercellular transfer of cellular contents in human malignant pleural mesothelioma. | PloS one 20120101 |
| N-cadherin mediates neuronal cell survival through Bim down-regulation. | PloS one 20120101 |
| Downregulation of HuR as a new mechanism of doxorubicin resistance in breast cancer cells. | Molecular cancer 20120101 |
| N-acetylcysteine protects against apoptosis through modulation of group I metabotropic glutamate receptor activity. | PloS one 20120101 |
| SCD1 inhibition causes cancer cell death by depleting mono-unsaturated fatty acids. | PloS one 20120101 |
| The tumor suppressive role of eIF3f and its function in translation inhibition and rRNA degradation. | PloS one 20120101 |
| Hypochlorite-induced oxidative stress elevates the capability of HDL in promoting breast cancer metastasis. | Journal of translational medicine 20120101 |
| Role of carotenoid β-cryptoxanthin in bone homeostasis. | Journal of biomedical science 20120101 |
| Evolutionary and Biochemical Aspects of Chemical Stress Resistance in Saccharomyces cerevisiae. | Frontiers in genetics 20120101 |
| Bak compensated for Bax in p53-null cells to release cytochrome c for the initiation of mitochondrial signaling during Withanolide D-induced apoptosis. | PloS one 20120101 |
| Mitochondrial dysfunction and adipogenic reduction by prohibitin silencing in 3T3-L1 cells. | PloS one 20120101 |
| Mitochondria death/survival signaling pathways in cardiotoxicity induced by anthracyclines and anticancer-targeted therapies. | Biochemistry research international 20120101 |
| Hyperglycemia and endothelial dysfunction in atherosclerosis: lessons from type 1 diabetes. | International journal of vascular medicine 20120101 |
| Novel Insights into the Interplay between Apoptosis and Autophagy. | International journal of cell biology 20120101 |
| Apoptotic-like activity of staurosporine in axenic cultures of Trypanosoma evansi. | Revista do Instituto de Medicina Tropical de Sao Paulo 20120101 |
| PKC-Mediated ZYG1 Phosphorylation Induces Fusion of Myoblasts as well as of Dictyostelium Cells. | International journal of cell biology 20120101 |
| Activation of cell cycle arrest and apoptosis by the proto-oncogene Pim-2. | PloS one 20120101 |
| The 5HT1a receptor agonist 8-Oh DPAT induces protection from lipofuscin accumulation and oxidative stress in the retinal pigment epithelium. | PloS one 20120101 |
| Cellular cytoskeleton dynamics modulates non-viral gene delivery through RhoGTPases. | PloS one 20120101 |
| Negative modulation of NMDA receptor channel function by DREAM/calsenilin/KChIP3 provides neuroprotection? | Frontiers in molecular neuroscience 20120101 |
| Ethanol-mediated regulation of cytochrome P450 2A6 expression in monocytes: role of oxidative stress-mediated PKC/MEK/Nrf2 pathway. | PloS one 20120101 |
| Lestaurtinib inhibits histone phosphorylation and androgen-dependent gene expression in prostate cancer cells. | PloS one 20120101 |
| Alternative macroautophagic pathways. | International journal of cell biology 20120101 |
| Molecular imaging with activatable reporter systems. | Theranostics 20120101 |
| Novel regulatory mechanisms for generation of the soluble leptin receptor: implications for leptin action. | PloS one 20120101 |
| Health and cellular impacts of air pollutants: from cytoprotection to cytotoxicity. | Biochemistry research international 20120101 |
| Enhancement of cell membrane invaginations, vesiculation and uptake of macromolecules by protonation of the cell surface. | PloS one 20120101 |
| Kaposi's Sarcoma-Associated Herpesvirus microRNAs. | Frontiers in microbiology 20120101 |
| IspE inhibitors identified by a combination of in silico and in vitro high-throughput screening. | PloS one 20120101 |
| High-content neurite development study using optically patterned substrates. | PloS one 20120101 |
| YopJ-induced caspase-1 activation in Yersinia-infected macrophages: independent of apoptosis, linked to necrosis, dispensable for innate host defense. | PloS one 20120101 |
| Vagal nerve stimulation rapidly activates brain-derived neurotrophic factor receptor TrkB in rat brain. | PloS one 20120101 |
| Down-regulation of GABA(A) receptor via promiscuity with the vasoactive peptide urotensin II receptor. Potential involvement in astrocyte plasticity. | PloS one 20120101 |
| β-Caryophyllene, a Compound Isolated from the Biblical Balm of Gilead (Commiphora gileadensis), Is a Selective Apoptosis Inducer for Tumor Cell Lines. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| Apoptotic HPV positive cancer cells exhibit transforming properties. | PloS one 20120101 |
| The SARAH Domain of RASSF1A and Its Tumor Suppressor Function. | Molecular biology international 20120101 |
| Regulation of neuronal cell death by c-Abl-Hippo/MST2 signaling pathway. | PloS one 20120101 |
| A functional screen provides evidence for a conserved, regulatory, juxtamembrane phosphorylation site in guanylyl cyclase a and B. | PloS one 20120101 |
| Non-antioxidant properties of α-tocopherol reduce the anticancer activity of several protein kinase inhibitors in vitro. | PloS one 20120101 |
| Effects of high glucose on AVP-induced hyperplasia, hypertrophy, and type IV collagen synthesis in cultured rat mesangial cells. | Endocrine research 20120101 |
| Induction of cell death in a glioblastoma line by hyperthermic therapy based on gold nanorods. | International journal of nanomedicine 20120101 |
| Inactivation of CDK/pRb pathway normalizes survival pattern of lymphoblasts expressing the FTLD-progranulin mutation c.709-1G>A. | PloS one 20120101 |
| MAVS ubiquitination by the E3 ligase TRIM25 and degradation by the proteasome is involved in type I interferon production after activation of the antiviral RIG-I-like receptors. | BMC biology 20120101 |
| The Arabidopsis CstF64-Like RSR1/ESP1 Protein Participates in Glucose Signaling and Flowering Time Control. | Frontiers in plant science 20120101 |
| Plant development, auxin, and the subsystem incompleteness theorem. | Frontiers in plant science 20120101 |
| Staurosporine inhibits frequency-dependent myofilament desensitization in intact rabbit cardiac trabeculae. | Biochemistry research international 20120101 |
| Radiation induces acute alterations in neuronal function. | PloS one 20120101 |
| Early decrease in respiration and uncoupling event independent of cytochrome C release in PC12 cells undergoing apoptosis. | International journal of cell biology 20120101 |
| Ubiquitous [Na+]i/[K+]i-sensitive transcriptome in mammalian cells: evidence for Ca(2+)i-independent excitation-transcription coupling. | PloS one 20120101 |
| Protectors or Traitors: The Roles of PON2 and PON3 in Atherosclerosis and Cancer. | Journal of lipids 20120101 |
| All in the Family: How the APPs Regulate Neurogenesis. | Frontiers in neuroscience 20120101 |
| GSK-3β: A Bifunctional Role in Cell Death Pathways. | International journal of cell biology 20120101 |
| Networked T cell death following macrophage infection by Mycobacterium tuberculosis. | PloS one 20120101 |
| Expression and Role of the Intermediate-Conductance Calcium-Activated Potassium Channel KCa3.1 in Glioblastoma. | Journal of signal transduction 20120101 |
| [Effect of inhibitors serine/threonine protein kinases and protein phosphatases on mitosis progression of synchronized tobacco by-2 cells]. | TSitologiia i genetika 20120101 |
| Maintenance of synaptic stability requires calcium-independent phospholipase A₂ activity. | Neural plasticity 20120101 |
| Laser-Based Propagation of Human iPS and ES Cells Generates Reproducible Cultures with Enhanced Differentiation Potential. | Stem cells international 20120101 |
| TIMP-1 induces an EMT-like phenotypic conversion in MDCK cells independent of its MMP-inhibitory domain. | PloS one 20120101 |
| Suppressive effect of maslinic acid on PMA-induced protein kinase C in human B-lymphoblastoid cells. | Asian Pacific journal of cancer prevention : APJCP 20120101 |
| H2O2 production downstream of FLT3 is mediated by p22phox in the endoplasmic reticulum and is required for STAT5 signalling. | PloS one 20120101 |
| Hax-1 is rapidly degraded by the proteasome dependent on its PEST sequence. | BMC cell biology 20120101 |
| Designing of Protein Kinase C β-II Inhibitors against Diabetic complications: Structure Based Drug Design, Induced Fit docking and analysis of active site conformational changes. | Bioinformation 20120101 |
| Application of flow cytometry to determine differential redistribution of cytochrome c and Smac/DIABLO from mitochondria during cell death signaling. | PloS one 20120101 |
| Staurosporine induces necroptotic cell death under caspase-compromised conditions in U937 cells. | PloS one 20120101 |
| DIDS prevents ischemic membrane degradation in cultured hippocampal neurons by inhibiting matrix metalloproteinase release. | PloS one 20120101 |
| The apoptotic volume decrease is an upstream event of MAP kinase activation during Staurosporine-induced apoptosis in HeLa cells. | International journal of molecular sciences 20120101 |
| Caspase-mediated truncation of tau potentiates aggregation. | International journal of Alzheimer's disease 20120101 |
| Increased expression of stefin B in the nucleus of T98G astrocytoma cells delays caspase activation. | Frontiers in molecular neuroscience 20120101 |
| SIRT1 activating compounds reduce oxidative stress and prevent cell death in neuronal cells. | Frontiers in cellular neuroscience 20120101 |
| C-terminal tetrapeptides inhibit Aβ42-induced neurotoxicity primarily through specific interaction at the N-terminus of Aβ42. | Journal of medicinal chemistry 20111222 |
| Structure-guided evolution of potent and selective CHK1 inhibitors through scaffold morphing. | Journal of medicinal chemistry 20111222 |
| Zn(II)-bis(cyclen) complexes and the imaging of apoptosis/necrosis. | Bioconjugate chemistry 20111221 |
| Dasatinib, imatinib and staurosporine capture compounds - Complementary tools for the profiling of kinases by Capture Compound Mass Spectrometry (CCMS). | Journal of proteomics 20111210 |
| Identification of inhibitors of the Leishmania cdc2-related protein kinase CRK3. | ChemMedChem 20111209 |
| Involvement of the mitochondrial compartment in human NCL fibroblasts. | Biochemical and biophysical research communications 20111209 |
| Alternative splicing of CARMA2/CARD14 transcripts generates protein variants with differential effect on NF-κB activation and endoplasmic reticulum stress-induced cell death. | Journal of cellular physiology 20111201 |
| Neuroprotective effects of MAPK/ERK1/2 and calpain inhibitors on lactacystin-induced cell damage in primary cortical neurons. | Neurotoxicology 20111201 |
| Phase I trial of 7-hydroxystaurosporine and fludararbine phosphate: in vivo evidence of 7-hydroxystaurosporine induced apoptosis in chronic lymphocytic leukemia. | Leukemia & lymphoma 20111201 |
| RhoGDI2 confers gastric cancer cells resistance against cisplatin-induced apoptosis by upregulation of Bcl-2 expression. | Cancer letters 20111201 |
| Heparanase enhances nerve-growth-factor-induced PC12 cell neuritogenesis via the p38 MAPK pathway. | The Biochemical journal 20111201 |
| tRNA structural and functional changes induced by oxidative stress. | Cellular and molecular life sciences : CMLS 20111201 |
| Stable over-expression of PPARβ/δ and PPARγ to examine receptor signaling in human HaCaT keratinocytes. | Cellular signalling 20111201 |
| Dual role of the mitochondrial protein frataxin in astrocytic tumors. | Laboratory investigation; a journal of technical methods and pathology 20111201 |
| Mitochondrial permeability and toxicity of diethylhexyl and monoethylhexyl phthalates on TK6 human lymphoblasts cells. | Toxicology in vitro : an international journal published in association with BIBRA 20111201 |
| M2, a novel anthracenedione, elicits a potent DNA damage response that can be subverted through checkpoint kinase inhibition to generate mitotic catastrophe. | Biochemical pharmacology 20111201 |
| Ca2+/calmodulin-dependent kinase (CaMK) signaling via CaMKI and AMP-activated protein kinase contributes to the regulation of WIPI-1 at the onset of autophagy. | Molecular pharmacology 20111201 |
| Pharmacological effects of exogenous NAD on mitochondrial bioenergetics, DNA repair, and apoptosis. | Molecular pharmacology 20111201 |
| ATP-NGF-complex, but not NGF, is the neuroprotective ligand. | Neurochemistry international 20111201 |
| Phospholipase C/Protein Kinase C pathway is essential for corneal re-epithelialization induced by Ap(4)A. | Current eye research 20111201 |
| Modulation of fungal sensitivity to staurosporine by targeting proteins identified by transcriptional profiling. | Fungal genetics and biology : FG & B 20111201 |
| Altered apoptotic responses in neurons lacking RhoB GTPase. | The European journal of neuroscience 20111201 |
| The mitochondrial protein C1qbp promotes cell proliferation, migration and resistance to cell death. | Cell cycle (Georgetown, Tex.) 20111201 |
| Poly(ADP-ribose) polymerase inhibition enhances p53-dependent and -independent DNA damage responses induced by DNA damaging agent. | Cell cycle (Georgetown, Tex.) 20111201 |
| Towards automated production and drug sensitivity testing using scaffold-free spherical tumor microtissues. | Biotechnology journal 20111201 |
| Kaposi's sarcoma herpesvirus microRNAs target caspase 3 and regulate apoptosis. | PLoS pathogens 20111201 |
| Norovirus regulation of the innate immune response and apoptosis occurs via the product of the alternative open reading frame 4. | PLoS pathogens 20111201 |
| Targeting of Mycobacterium tuberculosis heparin-binding hemagglutinin to mitochondria in macrophages. | PLoS pathogens 20111201 |
| Inhibition of apoptosis and NF-κB activation by vaccinia protein N1 occur via distinct binding surfaces and make different contributions to virulence. | PLoS pathogens 20111201 |
| Using multiple microenvironments to find similar ligand-binding sites: application to kinase inhibitor binding. | PLoS computational biology 20111201 |
| Seaweed polysaccharides and derived oligosaccharides stimulate defense responses and protection against pathogens in plants. | Marine drugs 20111201 |
| An investigation into the cytotoxic effects of 13-acetoxysarcocrassolide from the soft coral Sarcophyton crassocaule on bladder cancer cells. | Marine drugs 20111201 |
| Immunoregulatory potential of marine algal toxins yessotoxin and okadaic acid in mouse T lymphocyte cell line EL-4. | Toxicology letters 20111130 |
| Infectious bursal disease virus-induced activation of JNK signaling pathway is required for virus replication and correlates with virus-induced apoptosis. | Virology 20111125 |
| p38β-regulated induction of the heat shock response by carbon monoxide releasing molecule CORM-2 mediates cytoprotection in lung cells in vitro. | European journal of pharmacology 20111116 |
| Syntheses of phenylpyrazolodiazepin-7-ones as conformationally rigid analogs of aminopyrazole amide scaffold and their antiproliferative effects on cancer cells. | Bioorganic & medicinal chemistry 20111115 |
| Kinome siRNA-phosphoproteomic screen identifies networks regulating AKT signaling. | Oncogene 20111110 |
| Autophagic activity in cortical neurons under acute oxidative stress directly contributes to cell death. | Cellular and molecular life sciences : CMLS 20111101 |
| p53- and Bax-mediated apoptosis in injured rat spinal cord. | Neurochemical research 20111101 |
| Tauroursodeoxycholate (TUDCA) inhibits neointimal hyperplasia by suppression of ERK via PKCα-mediated MKP-1 induction. | Cardiovascular research 20111101 |
| RNA interference-mediated survivin gene knockdown induces growth arrest and reduced migration of vascular smooth muscle cells. | American journal of physiology. Heart and circulatory physiology 20111101 |
| Northeast Portuguese propolis protects against staurosporine and hydrogen peroxide-induced neurotoxicity in primary cortical neurons. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20111101 |
| Proteomic identification of Hsp70 as a new Plk1 substrate in arsenic trioxide-induced mitotically arrested cells. | Proteomics 20111101 |
| Systemic delivery of bone marrow-derived mesenchymal stromal cells diminishes neuropathology in a mouse model of Krabbe's disease. | Stem cells (Dayton, Ohio) 20111101 |
| Synthesis, biological evaluation, and molecular docking studies of 1,3,4-oxadiazole derivatives possessing 1,4-benzodioxan moiety as potential anticancer agents. | Bioorganic & medicinal chemistry 20111101 |
| Clinical experience with antiangiogenic therapy in leukemia. | Current cancer drug targets 20111101 |
| Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity. | Nature biotechnology 20111101 |
| Labdane diterpenes protect against anoxia/reperfusion injury in cardiomyocytes: involvement of AKT activation. | Cell death & disease 20111101 |
| Wavelength-dependent backscattering measurements for quantitative monitoring of apoptosis, part 1: early and late spectral changes are indicative of the presence of apoptosis in cell cultures. | Journal of biomedical optics 20111101 |
| Wavelength-dependent backscattering measurements for quantitative monitoring of apoptosis, part 2: early spectral changes during apoptosis are linked to apoptotic volume decrease. | Journal of biomedical optics 20111101 |
| Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells. | Oncotarget 20111101 |
| Comprehensive analysis of kinase inhibitor selectivity. | Nature biotechnology 20111030 |
| Drug-induced senescence generates chemoresistant stemlike cells with low reactive oxygen species. | The Journal of biological chemistry 20111028 |
| Proteome profiling reveals potential cellular targets of staurosporine using a clickable cell-permeable probe. | Chemical communications (Cambridge, England) 20111028 |
| Bioassay-guided isolation of constituents of Piper sarmentosum using a mitochondrial transmembrane potential assay. | Journal of natural products 20111028 |
| Transplantation of bone marrow-derived mesenchymal stem cells into the developing mouse eye. | Acta histochemica et cytochemica 20111026 |
| Cross-talk among intracellular signaling pathways mediates the diphenyl ditelluride actions on the hippocampal cytoskeleton of young rats. | Chemical research in toxicology 20111017 |
| Synthesis, biological evaluation and molecular docking studies of 1,3,4-thiadiazole derivatives containing 1,4-benzodioxan as potential antitumor agents. | Bioorganic & medicinal chemistry letters 20111015 |
| P73 regulates cisplatin-induced apoptosis in ovarian cancer cells via a calcium/calpain-dependent mechanism. | Oncogene 20111013 |
| 4-benzimidazolyl-3-phenylbutanoic acids as novel PIF-pocket-targeting allosteric inhibitors of protein kinase PKCζ. | Journal of medicinal chemistry 20111013 |
| Concentration-dependent effect of nerve growth factor on cell fate determination of neural progenitors. | Stem cells and development 20111001 |
| Proteasome inhibition can induce an autophagy-dependent apical activation of caspase-8. | Cell death and differentiation 20111001 |
| Co-occurrence of toxic bacterial and fungal secondary metabolites in moisture-damaged indoor environments. | Indoor air 20111001 |
| Mechanisms of xylanase-induced nitric oxide and phosphatidic acid production in tomato cells. | Planta 20111001 |
| Beclin 1-independent autophagy contributes to apoptosis in cortical neurons. | Autophagy 20111001 |
| Isoflurane decreases self-renewal capacity of rat cultured neural stem cells. | Anesthesiology 20111001 |
| FK506 ameliorates cell death features in Huntington's disease striatal cell models. | Neurochemistry international 20111001 |
| Arabidopsis thaliana alpha1,2-glucosyltransferase (ALG10) is required for efficient N-glycosylation and leaf growth. | The Plant journal : for cell and molecular biology 20111001 |
| Involvement of NGF in the rat model of persistent muscle pain associated with taut band. | The journal of pain : official journal of the American Pain Society 20111001 |
| Chlamydial antiapoptotic activity involves activation of the Raf/MEK/ERK survival pathway. | Current microbiology 20111001 |
| Cellular imaging assay for early evaluation of an apoptosis inducer. | Apoptosis : an international journal on programmed cell death 20111001 |
| Overexpression of CREG attenuates atherosclerotic endothelium apoptosis via VEGF/PI3K/AKT pathway. | Atherosclerosis 20111001 |
| Ishemia-reperfusion enhances GAPDH nitration in aging skeletal muscle. | Aging 20111001 |
| [Effects of staurosporine on the proliferation and apoptosis of prostate cancer PC-3 cells]. | Zhonghua nan ke xue = National journal of andrology 20111001 |
| ATP potentiates competitive inhibition of guanylyl cyclase A and B by the staurosporine analog, Gö6976: reciprocal regulation of ATP and GTP binding. | The Journal of biological chemistry 20110930 |
| The Rho1 GTPase-activating protein CgBem2 is required for survival of azole stress in Candida glabrata. | The Journal of biological chemistry 20110930 |
| Design and characterization of a potent and selective dual ATP- and substrate-competitive subnanomolar bidentate c-Jun N-terminal kinase (JNK) inhibitor. | Journal of medicinal chemistry 20110922 |
| Shiga toxin (Stx)1B and Stx2B induce von Willebrand factor secretion from human umbilical vein endothelial cells through different signaling pathways. | Blood 20110922 |
| Label-free imaging of cell attachment with photonic crystal enhanced microscopy. | The Analyst 20110921 |
| Thrombospondin-1 and angiotensin II inhibit soluble guanylyl cyclase through an increase in intracellular calcium concentration. | Biochemistry 20110913 |
| Staurosporine induces megakaryocytic differentiation through the upregulation of JAK/Stat3 signaling pathway. | Annals of hematology 20110901 |
| CDB-4124 does not cause apoptosis in cultured fibroid cells. | Reproductive sciences (Thousand Oaks, Calif.) 20110901 |
| On the mode of action of emodepside: slow effects on membrane potential and voltage-activated currents in Ascaris suum. | British journal of pharmacology 20110901 |
| Interleukin 4 induces the apoptosis of mouse microglial cells by a caspase-dependent mechanism. | Neurobiology of disease 20110901 |
| Tyrosine kinase inhibitors in the treatment of systemic mastocytosis. | Leukemia research 20110901 |
| Triggering of a novel intrinsic apoptosis pathway by the kinase inhibitor staurosporine: activation of caspase-9 in the absence of Apaf-1. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110901 |
| Decreased heat shock protein 27 expression and altered autophagy in human cells harboring A8344G mitochondrial DNA mutation. | Mitochondrion 20110901 |
| Reactive oxygen species participate in the p38-mediated apoptosis induced by potassium deprivation and staurosporine in cerebellar granule neurons. | The international journal of biochemistry & cell biology 20110901 |
| Studying protein-protein affinity and immobilized ligand-protein affinity interactions using MS-based methods. | Analytical and bioanalytical chemistry 20110901 |
| Regulating TRAIL receptor-induced cell death at the membrane : a deadly discussion. | Recent patents on anti-cancer drug discovery 20110901 |
| ABCG2 is required to control the sonic hedgehog pathway in side population cells with stem-like properties. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20110901 |
| Stimulation of erythrocyte phospholipid scrambling by enniatin A. | Molecular nutrition & food research 20110901 |
| Synergistic growth inhibition of cancer cells harboring the RET/PTC1 oncogene by staurosporine and rotenone involves enhanced cell death. | Journal of biosciences 20110901 |
| Cell death regulation during influenza A virus infection by matrix (M1) protein: a model of viral control over the cellular survival pathway. | Cell death & disease 20110901 |
| Metformin inhibits melanoma development through autophagy and apoptosis mechanisms. | Cell death & disease 20110901 |
| Essential requirement of cytochrome c release for caspase activation by procaspase-activating compound defined by cellular models. | Cell death & disease 20110901 |
| A computational approach to finding novel targets for existing drugs. | PLoS computational biology 20110901 |
| Real-time cell electrophysiology using a multi-channel dielectrophoretic-dot microelectrode array. | Electrophoresis 20110901 |
| Direct effect of protein kinase C inhibitors on cardiovascular ion channels. | BMB reports 20110901 |
| Targeting of a chlamydial protease impedes intracellular bacterial growth. | PLoS pathogens 20110901 |
| Vaccinia extracellular virions enter cells by macropinocytosis and acid-activated membrane rupture. | The EMBO journal 20110831 |
| Conserved core substructures in the overlay of protein-ligand complexes. | Journal of chemical information and modeling 20110822 |
| Are mitochondrial reactive oxygen species required for autophagy? | Biochemical and biophysical research communications 20110819 |
| KIT-D816V-independent oncogenic signaling in neoplastic cells in systemic mastocytosis: role of Lyn and Btk activation and disruption by dasatinib and bosutinib. | Blood 20110818 |
| ATM protects against oxidative stress induced by oxidized low-density lipoprotein. | DNA repair 20110815 |
| Lidocaine-induced apoptosis of gingival fibroblasts: participation of cAMP and PKC activity. | Cell biology international 20110801 |
| The protective role of the pericellular matrix in chondrocyte apoptosis. | Tissue engineering. Part A 20110801 |
| Protein kinase C is likely to be involved in zoosporogenesis and maintenance of flagellar motility in the peronosporomycete zoospores. | Molecular plant-microbe interactions : MPMI 20110801 |
| Phagocytosis of melanized Aspergillus conidia by macrophages exerts cytoprotective effects by sustained PI3K/Akt signalling. | Cellular microbiology 20110801 |
| Enhanced survival of skeletal muscle myoblasts in response to overexpression of cold shock protein RBM3. | American journal of physiology. Cell physiology 20110801 |
| Phosphorylation of Ser45 and Ser59 of αB-crystallin and p38/extracellular regulated kinase activity determine αB-crystallin-mediated protection of rat brain astrocytes from C2-ceramide- and staurosporine-induced cell death. | Journal of neurochemistry 20110801 |
| Pituitary adenylate cyclase-activating peptide induces long-lasting neuroprotection through the induction of activity-dependent signaling via the cyclic AMP response element-binding protein-regulated transcription co-activator 1. | Journal of neurochemistry 20110801 |
| Aging is associated with a proapoptotic endothelial progenitor cell phenotype. | Journal of vascular research 20110801 |
| Defective nuclear translocation of stress-activated signaling in senescent diploid human fibroblasts: a possible explanation for aging-associated apoptosis resistance. | Apoptosis : an international journal on programmed cell death 20110801 |
| Nitric oxide activates Nrf2 through S-nitrosylation of Keap1 in PC12 cells. | Nitric oxide : biology and chemistry 20110801 |
| Discovery of benzimidazole derivatives as novel multi-target EGFR, VEGFR-2 and PDGFR kinase inhibitors. | Bioorganic & medicinal chemistry 20110801 |
| K252a suppresses neuronal cells apoptosis through inhibiting the translocation of Bax to mitochondria induced by the MLK3/JNK signaling after transient global brain ischemia in rat hippocampal CA1 subregion. | Journal of receptor and signal transduction research 20110801 |
| A new staurosporine analog from Actinomycetes Streptomyces sp. (172614). | Journal of Asian natural products research 20110801 |
| FLT3 inhibition as therapy in acute myeloid leukemia: a record of trials and tribulations. | The oncologist 20110801 |
| Suppressor of cytokine signaling-1 (SOCS1) inhibits lymphocyte recruitment into the retina and protects SOCS1 transgenic rats and mice from ocular inflammation. | Investigative ophthalmology & visual science 20110801 |
| Salmonella bongori provides insights into the evolution of the Salmonellae. | PLoS pathogens 20110801 |
| Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission. | The EMBO journal 20110720 |
| The alkaline tolerance in Arabidopsis requires stabilizing microfilament partially through inactivation of PKS5 kinase. | Journal of genetics and genomics = Yi chuan xue bao 20110720 |
| Progress in structure based drug design for G protein-coupled receptors. | Journal of medicinal chemistry 20110714 |
| Label-free, single protein detection on a near-infrared fluorescent single-walled carbon nanotube/protein microarray fabricated by cell-free synthesis. | Nano letters 20110713 |
| Induction of Per1 expression following an experimentally induced epilepsy in the mouse hippocampus. | Neuroscience letters 20110708 |
| PI3Kinase signaling in glioblastoma. | Journal of neuro-oncology 20110701 |
| Endocytosis of cationized ferritin in marginal cells of the stria vascularis is regulated by protein kinase, protein phosphatase, and MEK/ERK and PI3-K signaling pathways. | Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20110701 |
| Enhanced contractility and myosin phosphorylation induced by Ca(2+)-independent MLCK activity in hypertensive rats. | Cardiovascular research 20110701 |
| Bacterial expression and purification of active hematopoietic cell kinase. | Protein expression and purification 20110701 |
| A group IIA-secreted phospholipase A2 from snake venom induces lipid body formation in macrophages: the roles of intracellular phospholipases A2 and distinct signaling pathways. | Journal of leukocyte biology 20110701 |
| Apoptosis induced by overall metabolic stress converges on the Bcl-2 family proteins Noxa and Mcl-1. | Apoptosis : an international journal on programmed cell death 20110701 |
| Impaired CNS leptin action is implicated in depression associated with obesity. | Endocrinology 20110701 |
| Effects of extracellular calcium concentration on neurite outgrowth in PC12 cells by staurosporine. | Neuroscience letters 20110701 |
| Aryl hydrocarbon receptor-dependent induction of apoptosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin in cerebellar granule cells from mouse. | Journal of neurochemistry 20110701 |
| Identification of new inhibitors of protein kinase R guided by statistical modeling. | Bioorganic & medicinal chemistry letters 20110701 |
| Neuroprotective signaling mechanisms of telomerase are regulated by brain-derived neurotrophic factor in rat spinal cord motor neurons. | Journal of neuropathology and experimental neurology 20110701 |
| Association of sperm morphology and the sperm deformity index (SDI) with poly (ADP-ribose) polymerase (PARP) cleavage inhibition. | Fertility and sterility 20110630 |
| Upregulation of CREB-mediated transcription enhances both short- and long-term memory. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110615 |
| Time-lapse, single cell based confocal imaging analysis of caspase activation and phosphatidylserine flipping during cellular apoptosis. | Biotechnic & histochemistry : official publication of the Biological Stain Commission 20110601 |
| A Phase 1 study of UCN-01 in combination with irinotecan in patients with resistant solid tumor malignancies. | Cancer chemotherapy and pharmacology 20110601 |
| Retro-inversion of certain cell-penetrating peptides causes severe cellular toxicity. | Biochimica et biophysica acta 20110601 |
| Characterization of the transcriptional signature of C/EBPbeta isoforms (LAP/LIP) in Hep3B cells: implication of LIP in pro-survival functions. | Journal of hepatology 20110601 |
| Involvement of histaminergic receptor mechanisms in the stimulation of NT-3 synthesis in astrocytes. | Neuropharmacology 20110601 |
| Up-regulation of homeodomain genes, DLX1 and DLX2, by FLT3 signaling. | Haematologica 20110601 |
| New insights into the control of HIV-1 transcription: when Tat meets the 7SK snRNP and super elongation complex (SEC). | Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20110601 |
| Discovery, synthesis, and investigation of the antitumor activity of novel piperazinylpyrimidine derivatives. | European journal of medicinal chemistry 20110601 |
| Intrinsic apoptotic pathway is subverted in mouse macrophages persistently infected by RSV. | Virus research 20110601 |
| Drug-eluting microarrays for cell-based screening of chemical-induced apoptosis. | Analytical chemistry 20110601 |
| Autophagy and ATP-induced anti-apoptosis in antigen presenting cells (APC) follows the cytokine storm in patients after major trauma. | Journal of cell communication and signaling 20110601 |
| Curcumin attenuates staurosporine-mediated death of retinal ganglion cells. | Investigative ophthalmology & visual science 20110601 |
| Evaluation of the physical and in vitro protective activity of three synthetic peptides derived from the pro- and mature GDNF sequence. | Neuropeptides 20110601 |
| Exploration of acridine scaffold as a potentially interesting scaffold for discovering novel multi-target VEGFR-2 and Src kinase inhibitors. | Bioorganic & medicinal chemistry 20110601 |
| Utilizing mitochondrial events as biomarkers for imaging apoptosis. | Cell death & disease 20110601 |
| Induction of Noxa-mediated apoptosis by modified vaccinia virus Ankara depends on viral recognition by cytosolic helicases, leading to IRF-3/IFN-β-dependent induction of pro-apoptotic Noxa. | PLoS pathogens 20110601 |
| Biochemical aspects of nitric oxide synthase feedback regulation by nitric oxide. | Interdisciplinary toxicology 20110601 |
| [Interaction of protein kinase C-extracellular signal-regulated kinase 1/2 signal pathway in the process of plasminogen activator inhibitor-1 expression induced by nicotine in human umbilical vein endothelial cells]. | Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20110601 |
| Immunohistochemical study on the expression of calcium binding proteins (calbindin-D28k, calretinin, and parvalbumin) in the cerebral cortex and in the hippocampal region of nNOS knock-out(-/-) mice. | Anatomy & cell biology 20110601 |
| The Interface between Cytoskeletal Aberrations and Mitochondrial Dysfunction in Alzheimer's Disease and Related Disorders. | Experimental neurobiology 20110601 |
| Cytotoxic and NF-κB inhibitory constituents of the stems of Cratoxylum cochinchinense and their semisynthetic analogues. | Journal of natural products 20110527 |
| Marianins A and B, prenylated phenylpropanoids from Mariannaea camptospora. | Journal of natural products 20110527 |
| Resorcylic acid lactones with cytotoxic and NF-κB inhibitory activities and their structure-activity relationships. | Journal of natural products 20110527 |
| Akt phosphorylation on Thr308 but not on Ser473 correlates with Akt protein kinase activity in human non-small cell lung cancer. | British journal of cancer 20110524 |
| Identification, in vitro activity and mode of action of phosphoinositide-dependent-1 kinase inhibitors as antifungal molecules. | ACS chemical biology 20110520 |
| Intestinal Na(+)/Ca(2+) exchanger protein and gene expression are regulated by 1,25(OH)(2)D(3) in vitamin D-deficient chicks. | Archives of biochemistry and biophysics 20110515 |
| Pharmacophore modeling and virtual screening for novel acidic inhibitors of microsomal prostaglandin E₂ synthase-1 (mPGES-1). | Journal of medicinal chemistry 20110512 |
| Activity-dependent transcription of BDNF enhances visual acuity during development. | Neuron 20110512 |
| 2-Aminophenoxazine-3-one and 2-amino-4,4α-dihydro-4α,7-dimethyl-3H-phenoxazine-3-one cause cellular apoptosis by reducing higher intracellular pH in cancer cells. | Proceedings of the Japan Academy. Series B, Physical and biological sciences 20110511 |
| Nerve growth factor contribution via transient receptor potential vanilloid 1 to ectopic orofacial pain. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110511 |
| Hypersensitivity of mtDNA-depleted cells to staurosporine-induced apoptosis: roles of Bcl-2 downregulation and cathepsin B. | American journal of physiology. Cell physiology 20110501 |
| The involvement of a protein kinase in phototaxis and gravitaxis of Euglena gracilis. | Planta 20110501 |
| Properties and therapeutic potential of transient receptor potential channels with putative roles in adversity: focus on TRPC5, TRPM2 and TRPA1. | Current drug targets 20110501 |
| Metabolic signatures in apoptotic human cancer cell lines. | Omics : a journal of integrative biology 20110501 |
| Chk1 has an essential role in the survival of differentiated cortical neurons in the absence of DNA damage. | Apoptosis : an international journal on programmed cell death 20110501 |
| Endoplasmic reticulum calcium release engages Bax translocation in cortical astrocytes. | Neurochemical research 20110501 |
| Lithium chloride and staurosporine potentiate the accumulation of phosphorylated glycogen synthase kinase 3β/Tyr216, resulting in glycogen synthase kinase 3β activation in SH-SY5Y human neuroblastoma cell lines. | Journal of neuroscience research 20110501 |
| Reactive oxygen species are related to ionic fluxes and volume decrease in apoptotic cerebellar granule neurons: role of NOX enzymes. | Journal of neurochemistry 20110501 |
| Microparticles as antigenic targets of antibodies to DNA and nucleosomes in systemic lupus erythematosus. | Journal of autoimmunity 20110501 |
| Determinants of mitotic catastrophe on abrogation of the G2 DNA damage checkpoint by UCN-01. | Molecular cancer therapeutics 20110501 |
| Balance of unidirectional monovalent ion fluxes in cells undergoing apoptosis: why does Na+/K+ pump suppression not cause cell swelling? | The Journal of physiology 20110501 |
| Mining a cathepsin inhibitor library for new antiparasitic drug leads. | PLoS neglected tropical diseases 20110501 |
| Combinations of protein-chemical complex structures reveal new targets for established drugs. | PLoS computational biology 20110501 |
| Effect of BMAP-28 antimicrobial peptides on Leishmania major promastigote and amastigote growth: role of leishmanolysin in parasite survival. | PLoS neglected tropical diseases 20110501 |
| The pathogenesis of Rift Valley fever. | Viruses 20110501 |
| Impairment of select forms of spatial memory and neurotrophin-dependent synaptic plasticity by deletion of glial aquaporin-4. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110427 |
| Bathymodiolamides A and B, ceramide derivatives from a deep-sea hydrothermal vent invertebrate mussel, Bathymodiolus thermophilus. | Journal of natural products 20110425 |
| 5-HT induces enhanced phrenic nerve activity via 5-HT(2A) receptor/PKC mechanism in anesthetized rats. | European journal of pharmacology 20110425 |
| Bit-1 mediates integrin-dependent cell survival through activation of the NFkappaB pathway. | The Journal of biological chemistry 20110422 |
| Disassembly of the JIP1/JNK molecular scaffold by caspase-3-mediated cleavage of JIP1 during apoptosis. | Experimental cell research 20110415 |
| TDP-43-induced death is associated with altered regulation of BIM and Bcl-xL and attenuated by caspase-mediated TDP-43 cleavage. | The Journal of biological chemistry 20110415 |
| Cytokeratin 18-mediated disorganization of intermediate filaments is induced by degradation of plectin in human liver cells. | Biochemical and biophysical research communications 20110415 |
| The synthesis and evaluation of indolylureas as PKCα inhibitors. | Bioorganic & medicinal chemistry 20110415 |
| Discovery of the first non-ATP competitive IGF-1R kinase inhibitors: advantages in comparison with competitive inhibitors. | Bioorganic & medicinal chemistry letters 20110415 |
| Structure of mammalian AMPK and its regulation by ADP. | Nature 20110414 |
| cAMP stimulation of StAR expression and cholesterol metabolism is modulated by co-expression of labile suppressors of transcription and mRNA turnover. | Molecular and cellular endocrinology 20110410 |
| Inhibition of PKMzeta in nucleus accumbens core abolishes long-term drug reward memory. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110406 |
| Dopamine D1 receptor-mediated inhibition of NADPH oxidase activity in human kidney cells occurs via protein kinase A-protein kinase C cross talk. | Free radical biology & medicine 20110401 |
| Zymosan suppresses leukotriene C₄ synthase activity in differentiating monocytes: antagonism by aspirin and protein kinase inhibitors. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110401 |
| LBH589, a deacetylase inhibitor, induces apoptosis in adult T-cell leukemia/lymphoma cells via activation of a novel RAIDD-caspase-2 pathway. | Leukemia 20110401 |
| Antiapoptotic effects of GLP-1 in murine HL-1 cardiomyocytes. | American journal of physiology. Heart and circulatory physiology 20110401 |
| Light- and sodium azide-induced death of RGC-5 cells in culture occurs via different mechanisms. | Apoptosis : an international journal on programmed cell death 20110401 |
| Exploration of (S)-3-aminopyrrolidine as a potentially interesting scaffold for discovery of novel Abl and PI3K dual inhibitors. | European journal of medicinal chemistry 20110401 |
| Structure-based design and biological profile of (E)-N-(4-Nitrobenzylidene)-2-naphthohydrazide, a novel small molecule inhibitor of IκB kinase-β. | European journal of medicinal chemistry 20110401 |
| The KEEP ON GOING protein of Arabidopsis recruits the ENHANCED DISEASE RESISTANCE1 protein to trans-Golgi network/early endosome vesicles. | Plant physiology 20110401 |
| Mitotic lymphoma cells are characterized by high expression of phosphorylated ribosomal S6 protein. | Histochemistry and cell biology 20110401 |
| Mechanisms of water transport mediated by PIP aquaporins and their regulation via phosphorylation events under salinity stress in barley roots. | Plant & cell physiology 20110401 |
| Contractile effect of tachykinins on rabbit small intestine. | Acta pharmacologica Sinica 20110401 |
| Systemic mastocytosis in adults: 2011 update on diagnosis, risk stratification, and management. | American journal of hematology 20110401 |
| Trypanosoma brucei glycogen synthase kinase-3, a target for anti-trypanosomal drug development: a public-private partnership to identify novel leads. | PLoS neglected tropical diseases 20110401 |
| Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1. | PLoS biology 20110401 |
| 1-(2-Hy-droxy-eth-yl)-3-[(2-hy-droxy-eth-yl)amino]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione. | Acta crystallographica. Section E, Structure reports online 20110401 |
| KIT signaling regulates MITF expression through miRNAs in normal and malignant mast cell proliferation. | Blood 20110331 |
| c-MYC suppresses BIN1 to release poly(ADP-ribose) polymerase 1: a mechanism by which cancer cells acquire cisplatin resistance. | Science signaling 20110329 |
| Human Polycomb protein 2 promotes α-synuclein aggregate formation through covalent SUMOylation. | Brain research 20110324 |
| FLT3 ligand impedes the efficacy of FLT3 inhibitors in vitro and in vivo. | Blood 20110324 |
| Synthetic studies on indolocarbazoles: total synthesis of staurosporine aglycon. | Organic letters 20110318 |
| Contribution of the intracellular C terminal domain to regulation of human P2X1 receptors for ATP by phorbol ester and Gq coupled mGlu(1α) receptors. | European journal of pharmacology 20110305 |
| Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response. | The EMBO journal 20110302 |
| Peroxiredoxin 6 interferes with TRAIL-induced death-inducing signaling complex formation by binding to death effector domain caspase. | Cell death and differentiation 20110301 |
| Nuclear translocation of anamorsin during drug-induced dopaminergic neurodegeneration in culture and in rat brain. | Journal of neural transmission (Vienna, Austria : 1996) 20110301 |
| Prostaglandins antagonistically control Bax activation during apoptosis. | Cell death and differentiation 20110301 |
| Inhibition of apoptosis by 60% oxygen: a novel pathway contributing to lung injury in neonatal rats. | American journal of physiology. Lung cellular and molecular physiology 20110301 |
| Cell death-resistance of differentiated myotubes is associated with enhanced anti-apoptotic mechanisms compared to myoblasts. | Apoptosis : an international journal on programmed cell death 20110301 |
| Kindling alters neurosteroid-induced modulation of phasic and tonic GABAA receptor-mediated currents: role of phosphorylation. | Journal of neurochemistry 20110301 |
| The RhoGAP domain-containing protein, Porf-2, inhibits proliferation and enhances apoptosis in neural stem cells. | Molecular and cellular neurosciences 20110301 |
| Neuroprotective effects of Mycoplasma hyorhinis against amyloid-β-peptide toxicity in SH-SY5Y human neuroblastoma cells are mediated by calpastatin upregulation in the mycoplasma-infected cells. | Neurochemistry international 20110301 |
| Involvement of p53 in cell death following cell cycle arrest and mitotic catastrophe induced by rotenone. | Biochimica et biophysica acta 20110301 |
| Kinetics, in silico docking, molecular dynamics, and MM-GBSA binding studies on prototype indirubins, KT5720, and staurosporine as phosphorylase kinase ATP-binding site inhibitors: the role of water molecules examined. | Proteins 20110301 |
| Synthesis of 3-phenylpyrazolopyrimidine-1,2,3-triazole conjugates and evaluation of their Src kinase inhibitory and anticancer activities. | Bioorganic & medicinal chemistry letters 20110301 |
| A rhodanese-like protein is highly overrepresented in the mutant S. clavuligerus oppA2::aph: effect on holomycin and other secondary metabolites production. | Microbial biotechnology 20110301 |
| Premature chromosome condensation induced by caffeine, 2-aminopurine, staurosporine and sodium metavanadate in S-phase arrested HeLa cells is associated with a decrease in Chk1 phosphorylation, formation of phospho-H2AX and minor cytoskeletal rearrangements. | Histochemistry and cell biology 20110301 |
| Luteinizing hormone (LH) acts through PKA and PKC to modulate T-type calcium currents and intracellular calcium transients in mice Leydig cells. | Cell calcium 20110301 |
| Role of Fas/FasL in regulation of inflammation in vaginal tissue during HSV-2 infection. | Cell death & disease 20110301 |
| Gain of survival signaling by down-regulation of three key miRNAs in brain of calorie-restricted mice. | Aging 20110301 |
| Schwann cells promote neurite outgrowth of dorsal root ganglion neurons through secretion of nerve growth factor. | Indian journal of experimental biology 20110301 |
| Increase of reduced nicotinamide adenine dinucleotide fluorescence lifetime precedes mitochondrial dysfunction in staurosporine-induced apoptosis of HeLa cells. | Journal of biomedical optics 20110301 |
| Miltefosine-induced apoptotic cell death on Leishmania major and L. tropica strains. | The Korean journal of parasitology 20110301 |
| Dissection of the influenza A virus endocytic routes reveals macropinocytosis as an alternative entry pathway. | PLoS pathogens 20110301 |
| Apoptosis induces Bcl-XS and cleaved Bcl-XL in chronic lymphocytic leukaemia. | Biochemical and biophysical research communications 20110218 |
| In vitro effect of different mediators of apoptosis on canine cranial and caudal cruciate ligament fibroblasts and its reversibility by pancaspase inhibitor zVAD.fmk. | Veterinary immunology and immunopathology 20110215 |
| The release of high mobility group box 1 in apoptosis is triggered by nucleosomal DNA fragmentation. | Archives of biochemistry and biophysics 20110215 |
| The DNA damage effector Chk1 kinase regulates Cdc14B nucleolar shuttling during cell cycle progression. | Cell cycle (Georgetown, Tex.) 20110215 |
| ICER evokes Dusp1-p38 pathway enhancing chemotherapy sensitivity in myeloid leukemia. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110215 |
| Rebeccamycin and staurosporine biosynthesis: insight into the mechanisms of the flavin-dependent monooxygenases RebC and StaC. | Chembiochem : a European journal of chemical biology 20110211 |
| Evidence for anti-angiogenic and pro-survival functions of the cerebral cavernous malformation protein 3. | Neurogenetics 20110201 |
| Specific activation of human neutrophils by scorpion venom: a flow cytometry assessment. | Toxicology in vitro : an international journal published in association with BIBRA 20110201 |
| Granulocyte macrophage-colony stimulating factor shows anti-apoptotic activity in neural progenitor cells via JAK/STAT5-Bcl-2 pathway. | Apoptosis : an international journal on programmed cell death 20110201 |
| Prevention of apoptosis by the interaction between FIH1 and Bax. | Molecular and cellular biochemistry 20110201 |
| Temporal effect of adrenocorticotrophic hormone on adrenal glucocorticoid steroidogenesis: involvement of the transducer of regulated cyclic AMP-response element-binding protein activity. | Journal of neuroendocrinology 20110201 |
| Soluble adenylyl cyclase mediates bicarbonate-dependent corneal endothelial cell protection. | American journal of physiology. Cell physiology 20110201 |
| MLH1 function is context dependent in colorectal cancers. | Journal of clinical pathology 20110201 |
| Activation of the Raf-MEK-ERK pathway is required for neutrophil extracellular trap formation. | Nature chemical biology 20110201 |
| C3b-induced eosinophil degranulation involves PI3-kinases and is inhibited by protein kinase C activity. | APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20110201 |
| Syntheses, antiproliferative activity and theoretical characterization of acitretin-type retinoids with changes in the lipophilic part. | European journal of medicinal chemistry 20110201 |
| Platelets prevent acute hepatitis induced by anti-fas antibody. | Journal of gastroenterology and hepatology 20110201 |
| Attenuation of the lysosomal death pathway by lysosomal cholesterol accumulation. | The American journal of pathology 20110201 |
| 2,4-Diaminopyrimidines as potent inhibitors of Trypanosoma brucei and identification of molecular targets by a chemical proteomics approach. | PLoS neglected tropical diseases 20110201 |
| Gadd45α activity is the principal effector of Shigella mitochondria-dependent epithelial cell death in vitro and ex vivo. | Cell death & disease 20110201 |
| The Rubella virus capsid is an anti-apoptotic protein that attenuates the pore-forming ability of Bax. | PLoS pathogens 20110201 |
| ChChd3, an inner mitochondrial membrane protein, is essential for maintaining crista integrity and mitochondrial function. | The Journal of biological chemistry 20110128 |
| Effects of mood stabilizers on adult dentate gyrus-derived neural precursor cells. | Progress in neuro-psychopharmacology & biological psychiatry 20110115 |
| Activated protein C N-linked glycans modulate cytoprotective signaling function on endothelial cells. | The Journal of biological chemistry 20110114 |
| Organometallic anticancer compounds. | Journal of medicinal chemistry 20110113 |
| Phosphorylated hMSH6: DNA mismatch versus DNA damage recognition. | Mutation research 20110110 |
| A tropomyosine receptor kinase inhibitor blocks spinal neuroplasticity essential for the anti-hypersensitivity effects of gabapentin and clonidine in rats with peripheral nerve injury. | The journal of pain : official journal of the American Pain Society 20110101 |
| The diterpenoid alkaloid noroxoaconitine is a Mapkap kinase 5 (MK5/PRAK) inhibitor. | Cellular and molecular life sciences : CMLS 20110101 |
| Structure of anticancer ruthenium half-sandwich complex bound to glycogen synthase kinase 3β. | Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20110101 |
| Running exercise protects the substantia nigra dopaminergic neurons against inflammation-induced degeneration via the activation of BDNF signaling pathway. | Brain, behavior, and immunity 20110101 |
| Role of cytoskeleton proteins in the morphological changes during apoptotic cell death of cerebellar granule neurons. | Neurochemical research 20110101 |
| Mitochondrial localization and regulation of BRAFV600E in thyroid cancer: a clinically used RAF inhibitor is unable to block the mitochondrial activities of BRAFV600E. | The Journal of clinical endocrinology and metabolism 20110101 |
| PEX13 deficiency in mouse brain as a model of Zellweger syndrome: abnormal cerebellum formation, reactive gliosis and oxidative stress. | Disease models & mechanisms 20110101 |
| Serum-free corneal organ culture medium (SFM) but not conventional minimal essential organ culture medium (MEM) protects human corneal endothelial cells from apoptotic and necrotic cell death. | The British journal of ophthalmology 20110101 |
| Effects of the protein kinase inhibitor PKC412 on gene expression and link to physiological effects in zebrafish Danio rerio eleuthero-embryos. | Toxicological sciences : an official journal of the Society of Toxicology 20110101 |
| Click chemistry inspired one-pot synthesis of 1,4-disubstituted 1,2,3-triazoles and their Src kinase inhibitory activity. | Bioorganic & medicinal chemistry letters 20110101 |
| Peroxisome proliferator-activated receptor activators protect sebocytes from apoptosis: a new treatment modality for acne? | The British journal of dermatology 20110101 |
| Role of group A p21-activated kinases in the anti-apoptotic activity of the pseudorabies virus US3 protein kinase. | Virus research 20110101 |
| Development of RET kinase inhibitors for targeted cancer therapy. | Current medicinal chemistry 20110101 |
| Characterization of tyrosine kinase and screening enzyme inhibitor by capillary electrophoresis with laser-induced fluoresce detector. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110101 |
| DR396, an apoptotic DNase γ inhibitor, attenuates high mobility group box 1 release from apoptotic cells. | Bioorganic & medicinal chemistry 20110101 |
| Evolutionary reshaping of fungal mating pathway scaffold proteins. | mBio 20110101 |
| Molecular basis for vulnerability to mitochondrial and oxidative stress in a neuroendocrine CRI-G1 cell line. | PloS one 20110101 |
| Nogo-B regulates migration and contraction of airway smooth muscle cells by decreasing ARPC 2/3 and increasing MYL-9 expression. | Respiratory research 20110101 |
| A humanin derivative reduces amyloid beta accumulation and ameliorates memory deficit in triple transgenic mice. | PloS one 20110101 |
| TRAIL receptor signaling regulation of chemosensitivity in vivo but not in vitro. | PloS one 20110101 |
| TNF-α contributes to caspase-3 independent apoptosis in neuroblastoma cells: role of NFAT. | PloS one 20110101 |
| Microarray analysis on human neuroblastoma cells exposed to aluminum, β(1-42)-amyloid or the β(1-42)-amyloid aluminum complex. | PloS one 20110101 |
| Inhibition of hedgehog signaling decreases proliferation and clonogenicity of human mesenchymal stem cells. | PloS one 20110101 |
| A novel soluble immune-type receptor (SITR) in teleost fish: carp SITR is involved in the nitric oxide-mediated response to a protozoan parasite. | PloS one 20110101 |
| The phagocytosis and toxicity of amorphous silica. | PloS one 20110101 |
| Cudrania tricupidata bureau (CTB) glycoprotein inhibits proliferation by Di(2-ethylhexyl) phthalate in primary splenocytes: responses in cell proliferation signaling. | Immunological investigations 20110101 |
| Neuropathic Nav1.3-mediated sensitization to P2X activation is regulated by protein kinase C. | Molecular pain 20110101 |
| Rottlerin Inhibits Lonicera japonica-Induced Photokilling in Human Lung Cancer Cells through Cytoskeleton-Related Signaling Cascade. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
| Mycobacterium indicus pranii supernatant induces apoptotic cell death in mouse peritoneal macrophages in vitro. | PloS one 20110101 |
| Jak2 is a negative regulator of ubiquitin-dependent endocytosis of the growth hormone receptor. | PloS one 20110101 |
| Are protozoan metacaspases potential parasite killers? | Parasites & vectors 20110101 |
| An unexpected role for the clock protein timeless in developmental apoptosis. | PloS one 20110101 |
| Glucose metabolism determines resistance of cancer cells to bioenergetic crisis after cytochrome-c release. | Molecular systems biology 20110101 |
| Analysis of multiple compound-protein interactions reveals novel bioactive molecules. | Molecular systems biology 20110101 |
| Vulnerability of polarised intestinal porcine epithelial cells to mycotoxin deoxynivalenol depends on the route of application. | PloS one 20110101 |
| Thiazole antibiotic thiostrepton synergize with bortezomib to induce apoptosis in cancer cells. | PloS one 20110101 |
| Beyond reduction of atherosclerosis: PON2 provides apoptosis resistance and stabilizes tumor cells. | Cell death & disease 20110101 |
| Ion channel inhibitors block caspase activation by mechanisms other than restoring intracellular potassium concentration. | Cell death & disease 20110101 |
| MAGUKs, scaffolding proteins at cell junctions, are substrates of different proteases during apoptosis. | Cell death & disease 20110101 |
| The nuclear guanine nucleotide exchange factors Ect2 and Net1 regulate RhoB-mediated cell death after DNA damage. | PloS one 20110101 |
| Sex-specific activation of cell death signalling pathways in cerebellar granule neurons exposed to oxygen glucose deprivation followed by reoxygenation. | ASN neuro 20110101 |
| Lentiviral vector mediated modification of mesenchymal stem cells & enhanced survival in an in vitro model of ischaemia. | Stem cell research & therapy 20110101 |
| EGFR and EGFRvIII undergo stress- and EGFR kinase inhibitor-induced mitochondrial translocalization: a potential mechanism of EGFR-driven antagonism of apoptosis. | Molecular cancer 20110101 |
| Identification of human IKK-2 inhibitors of natural origin (part I): modeling of the IKK-2 kinase domain, virtual screening and activity assays. | PloS one 20110101 |
| Successful targeting and disruption of an integrated reporter lentivirus using the engineered homing endonuclease Y2 I-AniI. | PloS one 20110101 |
| Signal pathways in astrocytes activated by cross-talk between of astrocytes and mast cells through CD40-CD40L. | Journal of neuroinflammation 20110101 |
| Calcium/calmodulin dependent protein kinase II bound to NMDA receptor 2B subunit exhibits increased ATP affinity and attenuated dephosphorylation. | PloS one 20110101 |
| Phorbol-Ester Mediated Suppression of hASH1 Synthesis: Multiple Ways to Keep the Level Down. | Frontiers in molecular neuroscience 20110101 |
| Therapeutic Implications of Targeting AKT Signaling in Melanoma. | Enzyme research 20110101 |
| Functional role of kallikrein 6 in regulating immune cell survival. | PloS one 20110101 |
| Comparison of the specificity of Trk inhibitors in recombinant and neuronal assays. | Neuropharmacology 20110101 |
| Lithocholic acid is an Eph-ephrin ligand interfering with Eph-kinase activation. | PloS one 20110101 |
| A growth factor attenuates HIV-1 Tat and morphine induced damage to human neurons: implication in HIV/AIDS-drug abuse cases. | PloS one 20110101 |
| p53 interaction with JMJD3 results in its nuclear distribution during mouse neural stem cell differentiation. | PloS one 20110101 |
| A theoretical entropy score as a single value to express inhibitor selectivity. | BMC bioinformatics 20110101 |
| Monitoring dynamic changes in mitochondrial calcium levels during apoptosis using a genetically encoded calcium sensor. | Journal of visualized experiments : JoVE 20110101 |
| Apoptotic sphingolipid ceramide in cancer therapy. | Journal of lipids 20110101 |
| Hypotonicity modulates tetrodotoxin-sensitive sodium current in trigeminal ganglion neurons. | Molecular pain 20110101 |
| Novel targeted therapeutics: inhibitors of MDM2, ALK and PARP. | Journal of hematology & oncology 20110101 |
| Comparative gene expression profiles induced by PPARγ and PPARα/γ agonists in human hepatocytes. | PloS one 20110101 |
| Analysis of Jak2 catalytic function by peptide microarrays: the role of the JH2 domain and V617F mutation. | PloS one 20110101 |
| GATA2 mediates thyrotropin-releasing hormone-induced transcriptional activation of the thyrotropin β gene. | PloS one 20110101 |
| Nicotinic acetylcholine receptor signaling in tumor growth and metastasis. | Journal of oncology 20110101 |
| Simultaneous siRNA targeting of Src and downstream signaling molecules inhibit tumor formation and metastasis of a human model breast cancer cell line. | PloS one 20110101 |
| ALMS1-deficient fibroblasts over-express extra-cellular matrix components, display cell cycle delay and are resistant to apoptosis. | PloS one 20110101 |
| hHGF overexpression in myoblast sheets enhances their angiogenic potential in rat chronic heart failure. | PloS one 20110101 |
| Characterization of a human cell line stably over-expressing the candidate oncogene, dual specificity phosphatase 12. | PloS one 20110101 |
| Cytotoxic and antimicrobial activity of pseudopterosins and seco-pseudopterosins isolated from the octocoral Pseudopterogorgia elisabethae of San Andrés and Providencia Islands (Southwest Caribbean Sea). | Marine drugs 20110101 |
| Interferon gamma activated macrophages kill mycobacteria by nitric oxide induced apoptosis. | PloS one 20110101 |
| A hepatoprotective Lindera obtusiloba extract suppresses growth and attenuates insulin like growth factor-1 receptor signaling and NF-kappaB activity in human liver cancer cell lines. | BMC complementary and alternative medicine 20110101 |
| Possible role of death receptor-mediated apoptosis by the E3 ubiquitin ligases Siah2 and POSH. | Molecular cancer 20110101 |
| Evaluation of iron oxide nanoparticle biocompatibility. | International journal of nanomedicine 20110101 |
| Distinct roles of Bcl-2 and Bcl-Xl in the apoptosis of human bone marrow mesenchymal stem cells during differentiation. | PloS one 20110101 |
| S-adenosyl-L-methionine activates actinorhodin biosynthesis by increasing autophosphorylation of the Ser/Thr protein kinase AfsK in Streptomyces coelicolor A3(2). | Bioscience, biotechnology, and biochemistry 20110101 |
| SULFs in human neoplasia: implication as progression and prognosis factors. | Journal of translational medicine 20110101 |
| Mechanisms of neuroprotection by protein disulphide isomerase in amyotrophic lateral sclerosis. | Neurology research international 20110101 |
| Firefly luciferase and RLuc8 exhibit differential sensitivity to oxidative stress in apoptotic cells. | PloS one 20110101 |
| Anchored FRET sensors detect local caspase activation prior to neuronal degeneration. | Molecular neurodegeneration 20110101 |
| Combination therapy with vemurafenib (PLX4032/RG7204) and metformin in melanoma cell lines with distinct driver mutations. | Journal of translational medicine 20110101 |
| FKBP51 protects 661w cell culture from staurosporine-induced apoptosis. | Molecular vision 20110101 |
| Binding of ATP to vascular endothelial growth factor isoform VEGF-A165 is essential for inducing proliferation of human umbilical vein endothelial cells. | BMC biochemistry 20110101 |
| Lack of a-disintegrin-and-metalloproteinase ADAM10 leads to intracellular accumulation and loss of shedding of the cellular prion protein in vivo. | Molecular neurodegeneration 20110101 |
| Structures, targets and recent approaches in anti-leishmanial drug discovery and development. | The open medicinal chemistry journal 20110101 |
| Nucleolar localization of RNA binding proteins induced by actinomycin D and heat shock in Trypanosoma cruzi. | PloS one 20110101 |
| Production of multiple brain-like ganglioside species is dispensable for fas-induced apoptosis of lymphoid cells. | PloS one 20110101 |
| Regulation of cell survival mechanisms in Alzheimer's disease by glycogen synthase kinase-3. | International journal of Alzheimer's disease 20110101 |
| In vitro and ex vivo evaluation of smart infra-red fluorescent caspase-3 probes for molecular imaging of cardiovascular apoptosis. | International journal of molecular imaging 20110101 |
| Raf-1 activation prevents caspase 9 processing downstream of apoptosome formation. | Journal of signal transduction 20110101 |
| High throughput ratio imaging to profile caspase activity: potential application in multiparameter high content apoptosis analysis and drug screening. | PloS one 20110101 |
| Human macrophages infected with a high burden of ESAT-6-expressing M. tuberculosis undergo caspase-1- and cathepsin B-independent necrosis. | PloS one 20110101 |
| p21(WAF1/CIP1) upregulation through the stress granule-associated protein CUGBP1 confers resistance to bortezomib-mediated apoptosis. | PloS one 20110101 |
| Chronic apocynin treatment attenuates beta amyloid plaque size and microglial number in hAPP(751)(SL) mice. | PloS one 20110101 |
| The current status and future directions of myxoma virus, a master in immune evasion. | Veterinary research 20110101 |
| Morphological analysis of CDC2 and glycogen synthase kinase 3β phosphorylation as markers of g2 → m transition in glioma. | Pathology research international 20110101 |
| Mechanisms of estrogens' dose-dependent neuroprotective and neurodamaging effects in experimental models of cerebral ischemia. | International journal of molecular sciences 20110101 |
| Bcl-x(L) blocks a mitochondrial inner membrane channel and prevents Ca2+ overload-mediated cell death. | PloS one 20110101 |
| The reconstruction of condition-specific transcriptional modules provides new insights in the evolution of yeast AP-1 proteins. | PloS one 20110101 |
| Antimetastatic effects of Phyllanthus on human lung (A549) and breast (MCF-7) cancer cell lines. | PloS one 20110101 |
| Equine torovirus (BEV) induces caspase-mediated apoptosis in infected cells. | PloS one 20110101 |
| Impairment of adult hippocampal neural progenitor proliferation by methamphetamine: role for nitrotyrosination. | Molecular brain 20110101 |
| Distinct biological effects of different nanoparticles commonly used in cosmetics and medicine coatings. | Cell & bioscience 20110101 |
| Valproic acid inhibits neural progenitor cell death by activation of NF-κB signaling pathway and up-regulation of Bcl-XL. | Journal of biomedical science 20110101 |
| Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection. | PloS one 20110101 |
| GABA(A) Receptors: Post-Synaptic Co-Localization and Cross-Talk with Other Receptors. | Frontiers in cellular neuroscience 20110101 |
| Cheating death: a coxiella effector prevents apoptosis. | Frontiers in microbiology 20110101 |
| Stage-related alterations in renal cell carcinoma--comprehensive quantitative analysis by 2D-DIGE and protein network analysis. | PloS one 20110101 |
| Protective effect of liposome-encapsulated glutathione in a human epidermal model exposed to a mustard gas analog. | Journal of toxicology 20110101 |
| Upregulation of cathepsin D in the caudate nucleus of primates with experimental parkinsonism. | Molecular neurodegeneration 20110101 |
| Milk lacking α-casein leads to permanent reduction in body size in mice. | PloS one 20110101 |
| Herpes simplex virus type 1 penetrates the basement membrane in human nasal respiratory mucosa. | PloS one 20110101 |
| Muscle atrophy induced by SOD1G93A expression does not involve the activation of caspase in the absence of denervation. | Skeletal muscle 20110101 |
| Caspase-3, myogenic transcription factors and cell cycle inhibitors are regulated by leukemia inhibitory factor to mediate inhibition of myogenic differentiation. | Skeletal muscle 20110101 |
| Evolutionary conservation of infection-induced cell death inhibition among Chlamydiales. | PloS one 20110101 |
| The Loss of HIF1α Leads to Increased Susceptibility to Cadmium-Chloride-Induced Toxicity in Mouse Embryonic Fibroblasts. | Journal of toxicology 20110101 |
| Glucocorticoid regulation of astrocytic fate and function. | PloS one 20110101 |
| Habitual short sleep duration and circulating endothelial progenitor cells. | Journal of cardiovascular disease research 20110101 |
| Recombinant VP1, an Akt inhibitor, suppresses progression of hepatocellular carcinoma by inducing apoptosis and modulation of CCL2 production. | PloS one 20110101 |
| Diacylglycerol signaling underlies astrocytic ATP release. | Neural plasticity 20110101 |
| Adeno-associated virus type 2 infection activates caspase dependent and independent apoptosis in multiple breast cancer lines but not in normal mammary epithelial cells. | Molecular cancer 20110101 |
| Pancreatic β-cell death in response to pro-inflammatory cytokines is distinct from genuine apoptosis. | PloS one 20110101 |
| Cytoplasmic accumulation and aggregation of TDP-43 upon proteasome inhibition in cultured neurons. | PloS one 20110101 |
| Differential inhibitor sensitivity between human kinases VRK1 and VRK2. | PloS one 20110101 |
| The C-terminal region of Bfl-1 sensitizes non-small cell lung cancer to gemcitabine-induced apoptosis by suppressing NF-κB activity and down-regulating Bfl-1. | Molecular cancer 20110101 |
| Host- and strain-specific regulation of influenza virus polymerase activity by interacting cellular proteins. | mBio 20110101 |
| Analysis of kinase gene expression in the frontal cortex of suicide victims: implications of fear and stress. | Frontiers in behavioral neuroscience 20110101 |
| Gemcitabine Overcomes Erlotinib Resistance in EGFR-Overexpressing Cancer Cells through Downregulation of Akt. | Journal of Cancer 20110101 |
| Mitotic catastrophe occurs in the absence of apoptosis in p53-null cells with a defective G1 checkpoint. | PloS one 20110101 |
| LRRK2 kinase activity is dependent on LRRK2 GTP binding capacity but independent of LRRK2 GTP binding. | PloS one 20110101 |
| Probiotic-derived polyphosphate enhances the epithelial barrier function and maintains intestinal homeostasis through integrin-p38 MAPK pathway. | PloS one 20110101 |
| β-Catenin signaling increases during melanoma progression and promotes tumor cell survival and chemoresistance. | PloS one 20110101 |
| CRMP2 hyperphosphorylation is characteristic of Alzheimer's disease and not a feature common to other neurodegenerative diseases. | Journal of Alzheimer's disease : JAD 20110101 |
| Protein profiling of human nonpigmented ciliary epithelium cell secretome: the differentiation factors characterization for retinal ganglion cell line. | Journal of biomedicine & biotechnology 20110101 |
| Dot/Icm type IVB secretion system requirements for Coxiella burnetii growth in human macrophages. | mBio 20110101 |
| Biosynthetic gene cluster for the cladoniamides, bis-indoles with a rearranged scaffold. | PloS one 20110101 |
| Conversion of commensal Escherichia coli K-12 to an invasive form via expression of a mutant histone-like protein. | mBio 20110101 |
| The use of HaloTag-based technology in flow and laser scanning cytometry analysis of live and fixed cells. | BMC research notes 20110101 |
| The novel immunosuppressive protein kinase C inhibitor sotrastaurin has no pro-viral effects on the replication cycle of hepatitis B or C virus. | PloS one 20110101 |
| Synergistic anticancer effects of the 9.2.27PE immunotoxin and ABT-737 in melanoma. | PloS one 20110101 |
| Modulation of cellular Hsp72 levels in undifferentiated and neuron-like SH-SY5Y cells determines resistance to staurosporine-induced apoptosis. | PloS one 20110101 |
| Bioluminescence-based high-throughput screen identifies pharmacological agents that target neurotransmitter signaling in small cell lung carcinoma. | PloS one 20110101 |
| Increased oxidative stress induces apoptosis in human cystic fibrosis cells. | PloS one 20110101 |
| Drug-tolerant cancer cells show reduced tumor-initiating capacity: depletion of CD44 cells and evidence for epigenetic mechanisms. | PloS one 20110101 |
| Improvement of capture compound mass spectrometry technology (CCMS) for the profiling of human kinases by combination with 2D LC-MS/MS. | Journal of biomedicine & biotechnology 20110101 |
| Maspin and MCM2 immunoprofiling in salivary gland carcinomas. | Diagnostic pathology 20110101 |
| Efficient elimination of cancer cells by deoxyglucose-ABT-263/737 combination therapy. | PloS one 20110101 |
| Neuronal deletion of caspase 8 protects against brain injury in mouse models of controlled cortical impact and kainic acid-induced excitotoxicity. | PloS one 20110101 |
| [On the theory of apoptotic decrease of the cell volume]. | Tsitologiia 20110101 |
| Screening for microbial metabolites affecting phenotype of Caenorhabditis elegans. | Biological & pharmaceutical bulletin 20110101 |
| Fine-tuning roles of endogenous brain-derived neurotrophic factor, TrkB and sortilin in colorectal cancer cell survival. | PloS one 20110101 |
| The eukaryotic-type serine/threonine protein kinase Stk is required for biofilm formation and virulence in Staphylococcus epidermidis. | PloS one 20110101 |
| Identification of a conserved anti-apoptotic protein that modulates the mitochondrial apoptosis pathway. | PloS one 20110101 |
| Reversible resistance induced by FLT3 inhibition: a novel resistance mechanism in mutant FLT3-expressing cells. | PloS one 20110101 |
| Autocrine netrin function inhibits glioma cell motility and promotes focal adhesion formation. | PloS one 20110101 |
| TTRAP is a novel component of the non-canonical TRAF6-TAK1 TGF-β signaling pathway. | PloS one 20110101 |
| Protein phosphatase 2a (PP2A) binds within the oligomerization domain of striatin and regulates the phosphorylation and activation of the mammalian Ste20-Like kinase Mst3. | BMC biochemistry 20110101 |
| MYCT1-TV, a novel MYCT1 transcript, is regulated by c-Myc and may participate in laryngeal carcinogenesis. | PloS one 20110101 |
| Survival of tumor cells after proton irradiation with ultra-high dose rates. | Radiation oncology (London, England) 20110101 |
| Association of reactive oxygen species-mediated signal transduction with in vitro apoptosis sensitivity in chronic lymphocytic leukemia B cells. | PloS one 20110101 |
| A potent inhibitor of SIK2, 3, 3', 7-trihydroxy-4'-methoxyflavon (4'-O-methylfisetin), promotes melanogenesis in B16F10 melanoma cells. | PloS one 20110101 |
| Mycobacterium tuberculosis infection induces non-apoptotic cell death of human dendritic cells. | BMC microbiology 20110101 |
| AUDocker LE: A GUI for virtual screening with AUTODOCK Vina. | BMC research notes 20110101 |
| Novel vaginal microflora colonization model providing new insight into microbicide mechanism of action. | mBio 20110101 |
| Compromising the unfolded protein response induces autophagy-mediated cell death in multiple myeloma cells. | PloS one 20110101 |
| The docking protein p130Cas regulates cell sensitivity to proteasome inhibition. | BMC biology 20110101 |
| Epilysin (matrix metalloproteinase-28) contributes to airway epithelial cell survival. | Respiratory research 20110101 |
| ATP competitive protein kinase C inhibitors demonstrate distinct state-dependent inhibition. | PloS one 20110101 |
| Characterization and functional modification of StaC and RebC, which are involved in the pyrrole oxidation of indolocarbazole biosynthesis. | Bioscience, biotechnology, and biochemistry 20110101 |
| GSK-3 Inhibitors: Preclinical and Clinical Focus on CNS. | Frontiers in molecular neuroscience 20110101 |
| Stanniocalcin-1 regulates re-epithelialization in human keratinocytes. | PloS one 20110101 |
| Mitochondrial peroxiredoxin III is a potential target for cancer therapy. | International journal of molecular sciences 20110101 |
| Kinase inhibitors from marine sponges. | Marine drugs 20110101 |
| Laser-based single-axon transection for high-content axon injury and regeneration studies. | PloS one 20110101 |
| Novel Phenazine 5,10-Dioxides Release OH in Simulated Hypoxia and Induce Reduction of Tumour Volume In Vivo. | ISRN pharmacology 20110101 |
| Superoxide dismutase 1 encoding mutations linked to ALS adopts a spectrum of misfolded states. | Molecular neurodegeneration 20110101 |
| An antibody to de-N-acetyl sialic acid containing-polysialic acid identifies an intracellular antigen and induces apoptosis in human cancer cell lines. | PloS one 20110101 |
| Fucoidan extract induces apoptosis in MCF-7 cells via a mechanism involving the ROS-dependent JNK activation and mitochondria-mediated pathways. | PloS one 20110101 |
| GSK-3 Mouse Models to Study Neuronal Apoptosis and Neurodegeneration. | Frontiers in molecular neuroscience 20110101 |
| The recognition of N-glycans by the lectin ArtinM mediates cell death of a human myeloid leukemia cell line. | PloS one 20110101 |
| Modeling of human prokineticin receptors: interactions with novel small-molecule binders and potential off-target drugs. | PloS one 20110101 |
| Neuroprotective Mechanisms of PPARδ: Modulation of Oxidative Stress and Inflammatory Processes. | PPAR research 20110101 |
| A quantitative method for the specific assessment of caspase-6 activity in cell culture. | PloS one 20110101 |
| Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer. | Breast cancer research : BCR 20110101 |
| Opposite temperature effect on transport activity of KCC2/KCC4 and N(K)CCs in HEK-293 cells. | BMC research notes 20110101 |
| Disruption of spectrin-like cytoskeleton in differentiating keratinocytes by PKCδ activation is associated with phosphorylated adducin. | PloS one 20110101 |
| Phosphorylation of AIB1 at mitosis is regulated by CDK1/CYCLIN B. | PloS one 20110101 |
| Latent Epstein-Barr virus can inhibit apoptosis in B cells by blocking the induction of NOXA expression. | PloS one 20110101 |
| The effects of a multiflavonoid supplement on vascular and hemodynamic parameters following acute exercise. | Oxidative medicine and cellular longevity 20110101 |
| Visible light may directly induce nuclear DNA damage triggering the death pathway in RGC-5 cells. | Molecular vision 20110101 |
| Endoplasmic reticulum stress pathway-mediated apoptosis in macrophages contributes to the survival of Mycobacterium tuberculosis. | PloS one 20110101 |
| Mechanisms of MEOX1 and MEOX2 regulation of the cyclin dependent kinase inhibitors p21 and p16 in vascular endothelial cells. | PloS one 20110101 |
| Lipid A decreases human erythrocytes deformability by increasing intracellular Ca(2+): effects of verapamil, staurosporine and the rho-kinase inhibitor Y-27632. | Clinical hemorheology and microcirculation 20110101 |
| A short caspase-3 isoform inhibits chemotherapy-induced apoptosis by blocking apoptosome assembly. | PloS one 20110101 |
| The Nrf1 CNC-bZIP protein is regulated by the proteasome and activated by hypoxia. | PloS one 20110101 |
| Molecular motor proteins and amyotrophic lateral sclerosis. | International journal of molecular sciences 20110101 |
| Inhibition of the Plasma-Membrane-Associated Serine Protease Cathepsin G by Mycobacterium tuberculosis Rv3364c Suppresses Caspase-1 and Pyroptosis in Macrophages. | Frontiers in microbiology 20110101 |
| Characterization of crude Echis carinatus venom-induced cytotoxicity in HEK 293T cells. | Journal of venom research 20110101 |
| Predicting the possibility of two newly isolated phenetheren ring containing compounds from Aristolochia manshuriensis as CDK2 inhibitors. | Bioinformation 20110101 |
| A novel potent tumour promoter aberrantly overexpressed in most human cancers. | Scientific reports 20110101 |
| Differential macrophage polarization promotes tissue remodeling and repair in a model of ischemic retinopathy. | Scientific reports 20110101 |
| Srebf1a is a key regulator of transcriptional control for adipogenesis. | Scientific reports 20110101 |
| Protein kinase C modulation of thermo-sensitive transient receptor potential channels: Implications for pain signaling. | Journal of natural science, biology, and medicine 20110101 |
| A novel role for CD46 in wound repair. | Frontiers in immunology 20110101 |
| Sex differences in brain aromatase activity: genomic and non-genomic controls. | Frontiers in endocrinology 20110101 |
| Neuroprotective actions of neurosteroids. | Frontiers in endocrinology 20110101 |
| Prostaglandins and their receptors in insect biology. | Frontiers in endocrinology 20110101 |
| Menadione triggers cell death through ROS-dependent mechanisms involving PARP activation without requiring apoptosis. | Free radical biology & medicine 20101215 |
| Corticosterone decreases the activity of rat glutamate transporter type 3 expressed in Xenopus oocytes. | Steroids 20101212 |
| Facilitation of long-term potentiation by muscarinic M(1) receptors is mediated by inhibition of SK channels. | Neuron 20101209 |
| The interaction between tropomyosin-related kinase B receptors and presynaptic muscarinic receptors modulates transmitter release in adult rodent motor nerve terminals. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20101208 |
| Protein kinase C βII and δ/θ play critical roles in bone morphogenic protein-4-stimulated osteoblastic differentiation of MC3T3-E1 cells. | Biochemical and biophysical research communications 20101203 |
| Binding to Na(+) /H(+) exchanger regulatory factor 2 (NHERF2) affects trafficking and function of the enteropathogenic Escherichia coli type III secretion system effectors Map, EspI and NleH. | Cellular microbiology 20101201 |
| The cell death regulator GRIM-19 is involved in HIV-1 induced T-cell apoptosis. | Apoptosis : an international journal on programmed cell death 20101201 |
| C2C12 myoblast sensitivity to different apoptotic chemical triggers. | Micron (Oxford, England : 1993) 20101201 |
| Mechanism of hCG-induced spermiation in the toad Rhinella arenarum (Amphibia, Anura). | General and comparative endocrinology 20101201 |
| Puromycin-sensitive aminopeptidase protects against aggregation-prone proteins via autophagy. | Human molecular genetics 20101201 |
| Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. | Toxicological sciences : an official journal of the Society of Toxicology 20101201 |
| Identification of p10 as a neurotoxic product generated from the proteolytic cleavage of the neuronal Cdk5 activator. | Journal of cellular biochemistry 20101201 |
| The lack of target specificity of small molecule anticancer kinase inhibitors is correlated with their ability to damage myocytes in vitro. | Toxicology and applied pharmacology 20101201 |
| Eicosapentaenoic acid restores diabetic tubular injury through regulating oxidative stress and mitochondrial apoptosis. | American journal of physiology. Renal physiology 20101201 |
| Smac mimetics: implications for enhancement of targeted therapies in leukemia. | Leukemia 20101201 |
| A comparative study of Lrrk2 function in primary neuronal cultures. | Parkinsonism & related disorders 20101201 |
| Protective effects of TRH and its analogues against various cytotoxic agents in retinoic acid (RA)-differentiated human neuroblastoma SH-SY5Y cells. | Neuropeptides 20101201 |
| Expression of type I GNRH receptor and in vivo and in vitro GNRH-I effects in corpora lutea of pseudopregnant rabbits. | The Journal of endocrinology 20101201 |
| Oligomerization of the mitochondrial protein voltage-dependent anion channel is coupled to the induction of apoptosis. | Molecular and cellular biology 20101201 |
| Mitochondrial fission and cristae disruption increase the response of cell models of Huntington's disease to apoptotic stimuli. | EMBO molecular medicine 20101201 |
| Positive inotropic, positive chronotropic and coronary vasodilatory effects of rat amylin: mechanisms of amylin-induced positive inotropy. | Acta physiologica Hungarica 20101201 |
| Mycobacterium tuberculosis eis regulates autophagy, inflammation, and cell death through redox-dependent signaling. | PLoS pathogens 20101201 |
| Structural basis for apoptosis inhibition by Epstein-Barr virus BHRF1. | PLoS pathogens 20101201 |
| The p53-target gene puma drives neutrophil-mediated protection against lethal bacterial sepsis. | PLoS pathogens 20101201 |
| Zfra is a small wizard in the mitochondrial apoptosis. | Aging 20101201 |
| Obatoclax induces Atg7-dependent autophagy independent of beclin-1 and BAX/BAK. | Cell death & disease 20101201 |
| Mutant huntingtin alters cell fate in response to microtubule depolymerization via the GEF-H1-RhoA-ERK pathway. | The Journal of biological chemistry 20101126 |
| Activation state-dependent binding of small molecule kinase inhibitors: structural insights from biochemistry. | Chemistry & biology 20101124 |
| Critical role for hyperpolarization-activated cyclic nucleotide-gated channel 2 in the AIF-mediated apoptosis. | The EMBO journal 20101117 |
| Potent inhibitors of amyloid β fibrillization, 4,5-dianilinophthalimide and staurosporine aglycone, enhance degradation of preformed aggregates of mutant Notch3. | Biochemical and biophysical research communications 20101105 |
| Inhibition of Drp1-dependent mitochondrial fragmentation and apoptosis by a polypeptide antagonist of calcineurin. | Cell death and differentiation 20101101 |
| Poly(ADP-ribose) polymerase 1 modulates the lethality of CHK1 inhibitors in carcinoma cells. | Molecular pharmacology 20101101 |
| Measurement of the thickness and volume of adherent cells using transmission-through-dye microscopy. | Pflugers Archiv : European journal of physiology 20101101 |
| Hypoxia downregulates p53 but induces apoptosis and enhances expression of BAD in cultures of human syncytiotrophoblasts. | American journal of physiology. Cell physiology 20101101 |
| PUMA induction by FoxO3a mediates the anticancer activities of the broad-range kinase inhibitor UCN-01. | Molecular cancer therapeutics 20101101 |
| Molecular basis of the core regulatory network in ABA responses: sensing, signaling and transport. | Plant & cell physiology 20101101 |
| Lily Cdc42/Rac-interactive binding motif-containing protein, a Rop target, involves calcium influx and phosphoproteins during pollen germination and tube growth. | Plant signaling & behavior 20101101 |
| HIV-1 induces DCIR expression in CD4+ T cells. | PLoS pathogens 20101101 |
| Detection of circulating tumor cells is improved by drug-induced antigen up-regulation: preclinical and clinical studies. | Anticancer research 20101101 |
| The in vitro cleavage of the hAtg proteins by cell death proteases. | Autophagy 20101101 |
| The role of apoptosis in mineralizing murine versus avian micromass culture systems. | Journal of cellular biochemistry 20101015 |
| Proteasomal degradation unleashes the pro-death activity of androgen receptor. | Cell research 20101001 |
| H1-receptor antagonists terfenadine and loratadine inhibit spontaneous growth of neoplastic mast cells. | Experimental hematology 20101001 |
| Requirement for distinct vesicle-associated membrane proteins in insulin- and AMP-activated protein kinase (AMPK)-induced translocation of GLUT4 and CD36 in cultured cardiomyocytes. | Diabetologia 20101001 |
| Differential responses of the mammalian retinal ganglion cell line RGC-5 to physiological stimuli and trophic factors. | Neurochemistry international 20101001 |
| Modulation of single-channel properties of TRPV1 by phosphorylation. | The Journal of physiology 20101001 |
| Angiotensin II enhances connecting tubule glomerular feedback. | Hypertension (Dallas, Tex. : 1979) 20101001 |
| QMOD: physically meaningful QSAR. | Journal of computer-aided molecular design 20101001 |
| Phase IIB trial of oral Midostaurin (PKC412), the FMS-like tyrosine kinase 3 receptor (FLT3) and multi-targeted kinase inhibitor, in patients with acute myeloid leukemia and high-risk myelodysplastic syndrome with either wild-type or mutated FLT3. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101001 |
| Hypoxia inducible factor-1α expression in areca quid chewing-associated oral squamous cell carcinomas. | Oral diseases 20101001 |
| Sodium butyrate with UCN-01 has marked antitumour activity against cervical cancer cells. | Anticancer research 20101001 |
| Low concentrations of nitric oxide delay the differentiation of embryonic stem cells and promote their survival. | Cell death & disease 20101001 |
| Caspase cleavage of the Golgi stacking factor GRASP65 is required for Fas/CD95-mediated apoptosis. | Cell death & disease 20101001 |
| Synergistic induction of cell death in liver tumor cells by TRAIL and chemotherapeutic drugs via the BH3-only proteins Bim and Bid. | Cell death & disease 20101001 |
| Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain. | The Biochemical journal 20100915 |
| Elevated BDNF after cocaine withdrawal facilitates LTP in medial prefrontal cortex by suppressing GABA inhibition. | Neuron 20100909 |
| A single seizure episode leads to rapid functional activation of KCC2 in the neonatal rat hippocampus. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100908 |
| Acetylcholinesterase is involved in apoptosis in the precursors of human muscle regeneration. | Chemico-biological interactions 20100906 |
| Zonisamide reduces cell death in SH-SY5Y cells via an anti-apoptotic effect and by upregulating MnSOD. | Neuroscience letters 20100906 |
| Endothelial progenitor cell function, apoptosis, and telomere length in overweight/obese humans. | Obesity (Silver Spring, Md.) 20100901 |
| Autophagy, a guardian against neurodegeneration. | Seminars in cell & developmental biology 20100901 |
| The bacterial effectors EspG and EspG2 induce a destructive calpain activity that is kept in check by the co-delivered Tir effector. | Cellular microbiology 20100901 |
| Vitellogenesis in Oncopeltus fasciatus: PLC/IP(3), DAG/PK-C pathway triggered by CaM. | Journal of insect physiology 20100901 |
| Development of a high-throughput AlphaScreen assay measuring full-length LRRK2(G2019S) kinase activity using moesin protein substrate. | Analytical biochemistry 20100901 |
| NGF-Dependent activation of TrkA pathway: A mechanism for the neuroprotective effect of troxerutin in D-galactose-treated mice. | Brain pathology (Zurich, Switzerland) 20100901 |
| Neurotrophic and neuroimmune responses to early-life Pseudomonas aeruginosa infection in rat lungs. | American journal of physiology. Lung cellular and molecular physiology 20100901 |
| Reduction in voltage-gated K+ channel activity in primary sensory neurons in painful diabetic neuropathy: role of brain-derived neurotrophic factor. | Journal of neurochemistry 20100901 |
| Androgens selectively protect against apoptosis in hippocampal neurones. | Journal of neuroendocrinology 20100901 |
| Lipid soluble smoke particles upregulate endothelin receptors in rat basilar artery. | Toxicology letters 20100901 |
| Midostaurin (PKC412) modulates differentiation and maturation of human myeloid dendritic cells. | Toxicology in vitro : an international journal published in association with BIBRA 20100901 |
| Ebolavirus is internalized into host cells via macropinocytosis in a viral glycoprotein-dependent manner. | PLoS pathogens 20100901 |
| Walleye dermal sarcoma virus: molecular biology and oncogenesis. | Viruses 20100901 |
| Neuroprotection signaling pathway of nerve growth factor and brain-derived neurotrophic factor against staurosporine induced apoptosis in hippocampal H19-7/IGF-IR [corrected]. | Experimental & molecular medicine 20100831 |
| Prolactin-induced Jak2 phosphorylation of RUSH: a key element in Jak/RUSH signaling. | Molecular and cellular endocrinology 20100830 |
| A coiled-coil enabled split-luciferase three-hybrid system: applied toward profiling inhibitors of protein kinases. | Journal of the American Chemical Society 20100825 |
| In vitro selection of a DNA-templated small-molecule library reveals a class of macrocyclic kinase inhibitors. | Journal of the American Chemical Society 20100825 |
| Novel phorbol ester-binding motif mediates hormonal activation of Na+/H+ exchanger. | The Journal of biological chemistry 20100820 |
| Thioredoxin-1 phosphorylated at T100 is needed for its anti-apoptotic activity in HepG2 cancer cells. | Life sciences 20100814 |
| The HGF/c-Met axis synergizes with G-CSF in the mobilization of hematopoietic stem/progenitor cells. | Stem cells and development 20100801 |
| Novel antibody derivatives for proteome and high-content analysis. | Analytical and bioanalytical chemistry 20100801 |
| Optic atrophy 3 as a protein of the mitochondrial outer membrane induces mitochondrial fragmentation. | Cellular and molecular life sciences : CMLS 20100801 |
| Analysis of protein kinase A activity in insulin-secreting cells using a cell-penetrating protein substrate and capillary electrophoresis. | Analytical and bioanalytical chemistry 20100801 |
| Monocytes are resistant to apoptosis in systemic juvenile idiopathic arthritis. | Clinical immunology (Orlando, Fla.) 20100801 |
| Novel 8-arylated purines as inhibitors of glycogen synthase kinase. | European journal of medicinal chemistry 20100801 |
| Protective effect of 4,4'-diaminodiphenylsulphone against oxidative stress but not to apoptotic stress in human diploid fibroblasts. | Free radical research 20100801 |
| Low-dose bafilomycin attenuates neuronal cell death associated with autophagy-lysosome pathway dysfunction. | Journal of neurochemistry 20100801 |
| NF-kappaB inducing kinase (NIK) inhibitors: identification of new scaffolds using virtual screening. | Bioorganic & medicinal chemistry letters 20100801 |
| p53-dependent G(1) arrest in 1st or 2nd cell cycle may protect human cancer cells from cell death after treatment with ionizing radiation and Chk1 inhibitors. | Cell proliferation 20100801 |
| Differential regulation of axon outgrowth and reinnervation by neurotrophin-3 and neurotrophin-4 in the hippocampal formation. | Experimental brain research 20100801 |
| Heat shock protein 90 inhibition depletes TrkA levels and signaling in human acute leukemia cells. | Molecular cancer therapeutics 20100801 |
| Abscisic acid increases Arabidopsis ABI5 transcription factor levels by promoting KEG E3 ligase self-ubiquitination and proteasomal degradation. | The Plant cell 20100801 |
| O-GlcNAc Modification: Friend or Foe in Diabetic Cardiovascular Disease. | Korean diabetes journal 20100801 |
| PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90. | PLoS pathogens 20100801 |
| Different types of cell death induced by enterotoxins. | Toxins 20100801 |
| Glucocorticoids promote survival of anti-inflammatory macrophages via stimulation of adenosine receptor A3. | Blood 20100722 |
| Hip2 interacts with and destabilizes Smac/DIABLO. | Biochemical and biophysical research communications 20100709 |
| p21 Downregulation is an important component of PAX3/FKHR oncogenicity and its reactivation by HDAC inhibitors enhances combination treatment. | Oncogene 20100708 |
| The human lung surfactant proteins A (SP-A) and D (SP-D) interact with apoptotic target cells by different binding mechanisms. | Immunobiology 20100701 |
| Dexmedetomidine provides cortical neuroprotection: impact on anaesthetic-induced neuroapoptosis in the rat developing brain. | Acta anaesthesiologica Scandinavica 20100701 |
| Structure-based and shape-complemented pharmacophore modeling for the discovery of novel checkpoint kinase 1 inhibitors. | Journal of molecular modeling 20100701 |
| Lipoxin A4 impairment of apoptotic signaling in macrophages: implication of the PI3K/Akt and the ERK/Nrf-2 defense pathways. | Cell death and differentiation 20100701 |
| Mechanisms of resistance against PKC412 in resistant FLT3-ITD positive human acute myeloid leukemia cells. | Annals of hematology 20100701 |
| Caspases-2 and -8 are involved in the presenilin1/gamma-secretase-dependent cleavage of amyloid precursor protein after the induction of apoptosis. | Journal of neuroscience research 20100701 |
| LmxMPK4, an essential mitogen-activated protein kinase of Leishmania mexicana is phosphorylated and activated by the STE7-like protein kinase LmxMKK5. | International journal for parasitology 20100701 |
| A comparison of differentiation protocols for RGC-5 cells. | Investigative ophthalmology & visual science 20100701 |
| Neuronal-driven angiogenesis: role of NGF in retinal neovascularization in an oxygen-induced retinopathy model. | Investigative ophthalmology & visual science 20100701 |
| High glucose regulates cyclin D1/E of human mesenchymal stem cells through TGF-beta1 expression via Ca2+/PKC/MAPKs and PI3K/Akt/mTOR signal pathways. | Journal of cellular physiology 20100701 |
| Characterization of BAG3 cleavage during apoptosis of pancreatic cancer cells. | Journal of cellular physiology 20100701 |
| Acute intrastriatal administration of quinolinic acid provokes hyperphosphorylation of cytoskeletal intermediate filament proteins in astrocytes and neurons of rats. | Experimental neurology 20100701 |
| The response to postnatal stress: amino acids transporters and PKC activity. | Neurochemical research 20100701 |
| LPLI inhibits apoptosis upstream of Bax translocation via a GSK-3beta-inactivation mechanism. | Journal of cellular physiology 20100701 |
| Calcium induces expression of cytoplasmic gelsolin in SH-SY5Y and HEK-293 cells. | Neurochemical research 20100701 |
| Dominant-negative VDAC1 mutants reveal oligomeric VDAC1 to be the active unit in mitochondria-mediated apoptosis. | The Biochemical journal 20100701 |
| Staurosporine increases toxicity of gemcitabine in non-small cell lung cancer cells: role of protein kinase C, deoxycytidine kinase and ribonucleotide reductase. | Anti-cancer drugs 20100701 |
| Protection of pancreatic beta-cells by group VIA phospholipase A(2)-mediated repair of mitochondrial membrane peroxidation. | Endocrinology 20100701 |
| Inhibition of brain-derived neurotrophic factor/tyrosine kinase B signaling suppresses choriocarcinoma cell growth. | Endocrinology 20100701 |
| Expression of TNF-alpha and IL-6 in HMC-1 cells treated with bisphenol A is attenuated by plant-originating glycoprotein (75 kDa) by blocking p38 MAPK. | Naunyn-Schmiedeberg's archives of pharmacology 20100701 |
| Biochemical characterization of in vitro phosphorylation and dephosphorylation of the plasma membrane H+-ATPase. | Plant & cell physiology 20100701 |
| Expression and modulation of connexin 30.2, a novel gap junction protein in the mouse retina. | Visual neuroscience 20100701 |
| Combining the FLT3 inhibitor PKC412 and the triterpenoid CDDO-Me synergistically induces apoptosis in acute myeloid leukemia with the internal tandem duplication mutation. | Molecular cancer research : MCR 20100701 |
| Bid regulates the pathogenesis of neurotropic reovirus. | PLoS pathogens 20100701 |
| HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction. | PLoS biology 20100701 |
| Epigenetic analysis of KSHV latent and lytic genomes. | PLoS pathogens 20100701 |
| Mitochondrial translocation of oxidized cofilin induces caspase-independent necrotic-like programmed cell death of T cells. | Cell death & disease 20100701 |
| Effective blockage of both the extrinsic and intrinsic pathways of apoptosis in mice by TAT-crmA. | The Journal of biological chemistry 20100625 |
| Probing the probes: fitness factors for small molecule tools. | Chemistry & biology 20100625 |
| Inhibition of protein kinase C-driven nuclear factor-kappaB activation: synthesis, structure-activity relationship, and pharmacological profiling of pathway specific benzimidazole probe molecules. | Journal of medicinal chemistry 20100624 |
| The protease-mediated nucleus shuttles of subnanometer gold quantum dots for real-time monitoring of apoptotic cell death. | Journal of the American Chemical Society 20100623 |
| Interactive medical case. A rash hypothesis. | The New England journal of medicine 20100617 |
| Nerve growth factor regulates the firing patterns and synaptic composition of motoneurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100616 |
| Study of benzo[a]phenazine 7,12-dioxide as selective hypoxic cytotoxin-scaffold. Identification of aerobic-antitumoral activity through DNA fragmentation. | Bioorganic & medicinal chemistry 20100615 |
| Subcellular distribution and expression of cofilin and ezrin in human colon adenocarcinoma cell lines with different metastatic potential. | European journal of histochemistry : EJH 20100614 |
| Elevated XIAP expression alone does not confer chemoresistance. | British journal of cancer 20100608 |
| Pro-apoptotic role of Cdc25A: activation of cyclin B1/Cdc2 by the Cdc25A C-terminal domain. | The Journal of biological chemistry 20100604 |
| Apaf-1-independent programmed cell death in mouse development. | Cell death and differentiation 20100601 |
| Ezrin is a key molecule in the metastasis of MOLT4 cells induced by CCL25/CCR9. | Leukemia research 20100601 |
| Angiostatic effects of K252a, a Trk inhibitor, in murine brain capillary endothelial cells. | Molecular and cellular biochemistry 20100601 |
| Mitochondrial K(ATP) channels-derived reactive oxygen species activate pro-survival pathway in pravastatin-induced cardioprotection. | Apoptosis : an international journal on programmed cell death 20100601 |
| TrkB/BDNF-dependent striatal plasticity and behavior in a genetic model of epilepsy: modulation by valproic acid. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100601 |
| The enteropathogenic Escherichia coli effector NleH inhibits apoptosis induced by Clostridium difficile toxin B. | Microbiology (Reading, England) 20100601 |
| Regulation of human organic anion transporter 3 by peptide hormone bradykinin. | The Journal of pharmacology and experimental therapeutics 20100601 |
| 2,3,7,8-Tetrachlorodibenzo-p-dioxin induces apoptosis in neural growth factor (NGF)-differentiated pheochromocytoma PC12 cells. | Neurotoxicology 20100601 |
| Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells. | Apoptosis : an international journal on programmed cell death 20100601 |
| Activation of volume-sensitive Cl(-) channel is involved in carboplatin-induced apoptosis in human lung adenocarcinoma cells. | Cancer biology & therapy 20100601 |
| Teratocarcinoma-derived growth factor-1 is upregulated in aldosterone-producing adenomas and increases aldosterone secretion and inhibits apoptosis in vitro. | Hypertension (Dallas, Tex. : 1979) 20100601 |
| A new player in apoptosis triggered with anticancer drugs: the volume-sensitive outwardly-rectifying Cl(-) channel. | Cancer biology & therapy 20100601 |
| Rotenone enhances the antifungal properties of staurosporine. | Eukaryotic cell 20100601 |
| B lymphocyte-induced maturation protein 1 is a novel target gene of aryl hydrocarbon receptor. | Journal of dermatological science 20100601 |
| Preapoptotic cell stress response of primary hepatocytes. | Hepatology (Baltimore, Md.) 20100601 |
| Serum-dependent selective expression of EhTMKB1-9, a member of Entamoeba histolytica B1 family of transmembrane kinases. | PLoS pathogens 20100601 |
| ATP allosteric activation of atrial natriuretic factor receptor guanylate cyclase. | The FEBS journal 20100601 |
| Differential evaluation of hepatocyte apoptosis and necrosis in acute liver injury. | Hepatology research : the official journal of the Japan Society of Hepatology 20100601 |
| [FLT3 kinase inhibitors for the treatment of acute leukemia]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20100601 |
| XIAP impairs Smac release from the mitochondria during apoptosis. | Cell death & disease 20100601 |
| Protein kinase RNA/FADD/caspase-8 pathway mediates the proapoptotic activity of the RNA-binding protein human antigen R (HuR). | The Journal of biological chemistry 20100528 |
| Molecular shape and medicinal chemistry: a perspective. | Journal of medicinal chemistry 20100527 |
| Pericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D-related protein 1 (BICDR-1) regulates neuritogenesis. | The EMBO journal 20100519 |
| Targeting slow-proliferating ovarian cancer cells. | International journal of cancer 20100515 |
| The role of the cysteine residue in the chaperone and anti-apoptotic functions of human Hsp27. | Journal of cellular biochemistry 20100515 |
| Dynamic processes that reflect anti-apoptotic strategies set up by HspB1 (Hsp27). | Experimental cell research 20100515 |
| Quantification of green fluorescent protein in cellular supernatant by capillary electrophoresis with laser-induced fluorescence detection for measurement of cell death. | Talanta 20100515 |
| Nuclear DBF-2-related kinases are essential regulators of cytokinesis in bloodstream stage Trypanosoma brucei. | The Journal of biological chemistry 20100514 |
| Role for ionic fluxes on cell death and apoptotic volume decrease in cultured cerebellar granule neurons. | Neuroscience 20100505 |
| Staurosporine-induced programmed cell death in Blastocystis occurs independently of caspases and cathepsins and is augmented by calpain inhibition. | Microbiology (Reading, England) 20100501 |
| The fourth isoform of the adenine nucleotide translocator inhibits mitochondrial apoptosis in cancer cells. | The international journal of biochemistry & cell biology 20100501 |
| Involvement of ERK1/2, p38 and PI3K in megakaryocytic differentiation of K562 cells. | European journal of haematology 20100501 |
| Regulation of apoptosis-associated lysosomal membrane permeabilization. | Apoptosis : an international journal on programmed cell death 20100501 |
| The release of microparticles by Jurkat leukemia T cells treated with staurosporine and related kinase inhibitors to induce apoptosis. | Apoptosis : an international journal on programmed cell death 20100501 |
| Differential antiapoptotic effect of erythropoietin on undifferentiated and retinoic acid-differentiated SH-SY5Y cells. | Journal of cellular biochemistry 20100501 |
| Dynamic nucleocytoplasmic shuttling of an Arabidopsis SR splicing factor: role of the RNA-binding domains. | Plant physiology 20100501 |
| The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma. | Journal of hepatology 20100501 |
| Translocation of protein kinase C isoforms is involved in propofol-induced endothelial nitric oxide synthase activation. | British journal of anaesthesia 20100501 |
| A tomato bZIP transcription factor, SlAREB, is involved in water deficit and salt stress response. | Planta 20100501 |
| Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis. | Protein & cell 20100501 |
| Apoptosis protection by Mcl-1 and Bcl-2 modulation of inositol 1,4,5-trisphosphate receptor-dependent Ca2+ signaling. | The Journal of biological chemistry 20100430 |
| Cholesterol-dependent kinase activity regulates transmitter release from cerebellar synapses. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100428 |
| Functional interactions between nicotinic and P2X receptors in celiac ganglia neurons. | Autonomic neuroscience : basic & clinical 20100419 |
| Severe X-linked mitochondrial encephalomyopathy associated with a mutation in apoptosis-inducing factor. | American journal of human genetics 20100409 |
| Involvement of JNK in the regulation of autophagic cell death. | Oncogene 20100408 |
| Expression changes of K+-Cl- co-transporter 2 and Na+-K+-Cl- co-transporter1 in mouse trigeminal subnucleus caudalis following pulpal inflammation. | Brain research bulletin 20100405 |
| BEX2 regulates mitochondrial apoptosis and G1 cell cycle in breast cancer. | International journal of cancer 20100401 |
| Leukemia inhibitory factor-dependent increase in myoblast cell number is associated with phosphotidylinositol 3-kinase-mediated inhibition of apoptosis and not mitosis. | Experimental cell research 20100401 |
| Classical swine fever virus infection protects aortic endothelial cells from pIpC-mediated apoptosis. | The Journal of general virology 20100401 |
| Elucidating the role of requiem in the growth and death of Chinese hamster ovary cells. | Apoptosis : an international journal on programmed cell death 20100401 |
| Ion transport in a human lens epithelial cell line exposed to hyposmotic and apoptotic stress. | Journal of cellular physiology 20100401 |
| Beneficial effects of activation of PKC on hemorrhagic shock in rats. | The Journal of trauma 20100401 |
| Mitochondrial-dependent apoptosis in Huntington's disease human cybrids. | Experimental neurology 20100401 |
| Encystation process of Giardia lamblia: morphological and regulatory aspects. | Archives of microbiology 20100401 |
| Porphyromonas gingivalis infection sequesters pro-apoptotic Bad through Akt in primary gingival epithelial cells. | Molecular oral microbiology 20100401 |
| Protein kinase inhibition of clinically important staurosporine analogues. | Natural product reports 20100401 |
| Phosphorylation of conserved PIN motifs directs Arabidopsis PIN1 polarity and auxin transport. | The Plant cell 20100401 |
| Neisseria meningitidis induces brain microvascular endothelial cell detachment from the matrix and cleavage of occludin: a role for MMP-8. | PLoS pathogens 20100401 |
| Anti-melanoma activity of the 9.2.27PE immunotoxin in dacarbazine resistant cells. | Journal of immunotherapy (Hagerstown, Md. : 1997) 20100401 |
| Inhibition of MAPK/ERK, PKC and CaMKII signaling blocks cytolysin-induced human glioma cell death. | Anticancer research 20100401 |
| Tropheryma whipplei, the Whipple's disease bacillus, induces macrophage apoptosis through the extrinsic pathway. | Cell death & disease 20100401 |
| Identification of 2-anilino-9-methoxy-5,7-dihydro-6H-pyrimido[5,4-d][1]benzazepin-6-ones as dual PLK1/VEGF-R2 kinase inhibitor chemotypes by structure-based lead generation. | Journal of medicinal chemistry 20100325 |
| Enhanced vulnerability of PARK6 patient skin fibroblasts to apoptosis induced by proteasomal stress. | Neuroscience 20100317 |
| Mechanisms mediating CCK-8S-induced contraction of proximal colon in guinea pigs. | World journal of gastroenterology 20100307 |
| Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation. | The Journal of biological chemistry 20100305 |
| Biophysical and X-ray crystallographic analysis of Mps1 kinase inhibitor complexes. | Biochemistry 20100302 |
| Apoptosis- and necrosis-induced changes in light attenuation measured by optical coherence tomography. | Lasers in medical science 20100301 |
| The human cardiac K2P3.1 (TASK-1) potassium leak channel is a molecular target for the class III antiarrhythmic drug amiodarone. | Naunyn-Schmiedeberg's archives of pharmacology 20100301 |
| Fractalkine has anti-apoptotic and proliferative effects on human vascular smooth muscle cells via epidermal growth factor receptor signalling. | Cardiovascular research 20100301 |
| Cytoplasmic p53 and activated Bax regulate p53-dependent, transcription-independent neural precursor cell apoptosis. | The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20100301 |
| microRNA 21: response to hormonal therapies and regulatory function in leiomyoma, transformed leiomyoma and leiomyosarcoma cells. | Molecular human reproduction 20100301 |
| Bradykinin and high glucose promote renal tubular inflammation. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100301 |
| Regulation of K-Cl cotransport in erythrocytes of frog Rana temporaria by commonly used protein kinase and protein phosphatase inhibitors. | Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20100301 |
| Hypoxic enlarged mitochondria protect cancer cells from apoptotic stimuli. | Journal of cellular physiology 20100301 |
| Glucose induces pancreatic islet cell apoptosis that requires the BH3-only proteins Bim and Puma and multi-BH domain protein Bax. | Diabetes 20100301 |
| Late expression of brain-derived neurotrophic factor in the amygdala is required for persistence of fear memory. | Neurobiology of learning and memory 20100301 |
| Miniaturisation of a high throughput screening assay comparing air displacement and capillary-based nanolitre transfer technologies. | Combinatorial chemistry & high throughput screening 20100301 |
| Goniothalamin-induced oxidative stress, DNA damage and apoptosis via caspase-2 independent and Bcl-2 independent pathways in Jurkat T-cells. | Toxicology letters 20100301 |
| Linking species concepts to natural product discovery in the post-genomic era. | Journal of industrial microbiology & biotechnology 20100301 |
| Neuronal differentiation by analogs of staurosporine. | Neurochemistry international 20100301 |
| Rhythmic contraction generates adjustable passive stiffness in rabbit detrusor. | Journal of applied physiology (Bethesda, Md. : 1985) 20100301 |
| Maintenance therapy in acute myeloid leukemia revisited: will new agents rekindle an old interest? | Current opinion in hematology 20100301 |
| Network generation enhances interpretation of proteomic data from induced apoptosis. | Proteomics 20100301 |
| Colony stimulating factor-1 receptor as a target for small molecule inhibitors. | Bioorganic & medicinal chemistry 20100301 |
| The anti-apoptotic function of human αA-crystallin is directly related to its chaperone activity. | Cell death & disease 20100301 |
| Down-regulation of S1P1 receptor surface expression by protein kinase C inhibition. | The Journal of biological chemistry 20100226 |
| Inhibition of protein kinase Akt1 by apoptosis signal-regulating kinase-1 (ASK1) is involved in apoptotic inhibition of regulatory volume increase. | The Journal of biological chemistry 20100226 |
| Alpha2,6-sialic acid on platelet endothelial cell adhesion molecule (PECAM) regulates its homophilic interactions and downstream antiapoptotic signaling. | The Journal of biological chemistry 20100226 |
| Sceptrin, a marine natural compound, inhibits cell motility in a variety of cancer cell lines. | ACS chemical biology 20100219 |
| Golgi apparatus casein kinase phosphorylates bioactive Ser-6 of bone morphogenetic protein 15 and growth and differentiation factor 9. | FEBS letters 20100219 |
| FLT3-mutant allelic burden and clinical status are predictive of response to FLT3 inhibitors in AML. | Blood 20100218 |
| Suppression of the intrinsic apoptosis pathway by synaptic activity. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100217 |
| Calcium homeostasis and its relationship to superoxide production in blood and milk neutrophils of lactating goats. | Veterinary immunology and immunopathology 20100215 |
| Structural basis of human p70 ribosomal S6 kinase-1 regulation by activation loop phosphorylation. | The Journal of biological chemistry 20100212 |
| Vaccinia virus F1L interacts with Bak using highly divergent Bcl-2 homology domains and replaces the function of Mcl-1. | The Journal of biological chemistry 20100212 |
| Angiotensin II inhibits activity of human organic anion transporter 3 through activation of protein kinase Calpha: accelerating endocytosis of the transporter. | European journal of pharmacology 20100210 |
| Protein kinase C is inhibited by bisphosphonates in prostate cancer PC-3 cells. | European journal of pharmacology 20100210 |
| Annexin-II, DNA, and histones serve as factor H ligands on the surface of apoptotic cells. | The Journal of biological chemistry 20100205 |
| Comprehensive identification of staurosporine-binding kinases in the hepatocyte cell line HepG2 using Capture Compound Mass Spectrometry (CCMS). | Journal of proteome research 20100205 |
| Randomized clinical trials with biomarkers: design issues. | Journal of the National Cancer Institute 20100203 |
| Phenolic fraction of tobacco smoke condensate potentiates benzo[a]pyerene diol epoxide-induced cell transformation: role of protein kinase C. | Mutation research 20100202 |
| Association between circulating osteoprogenitor cell numbers and bone mineral density in postmenopausal osteoporosis. | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20100201 |
| Osmotic stress stimulates generation of superoxide anion by spermatozoa in horses. | Animal reproduction science 20100201 |
| Characterization of two novel SETX mutations in AOA2 patients reveals aspects of the pathophysiological role of senataxin. | Neurogenetics 20100201 |
| Activation of ERK1/2 by protein kinase C-alpha in response to hydrogen peroxide-induced cell death in human gingival fibroblasts. | Toxicology in vitro : an international journal published in association with BIBRA 20100201 |
| Endothelin signalling in arterial smooth muscle is tightly regulated by G protein-coupled receptor kinase 2. | Cardiovascular research 20100201 |
| BAK and BAX deletion using zinc-finger nucleases yields apoptosis-resistant CHO cells. | Biotechnology and bioengineering 20100201 |
| Brain-derived neurotrophic factor signaling modulates cocaine induction of reward-associated ultrasonic vocalization in rats. | The Journal of pharmacology and experimental therapeutics 20100201 |
| Regulatory role of monoamine neurotransmitters in astrocytic NT-3 synthesis. | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20100201 |
| Lack of TXNIP protects against mitochondria-mediated apoptosis but not against fatty acid-induced ER stress-mediated beta-cell death. | Diabetes 20100201 |
| CFTR mediates apoptotic volume decrease and cell death by controlling glutathione efflux and ROS production in cultured mice proximal tubules. | American journal of physiology. Renal physiology 20100201 |
| Cadmium-induced DNA damage triggers G(2)/M arrest via chk1/2 and cdc2 in p53-deficient kidney proximal tubule cells. | American journal of physiology. Renal physiology 20100201 |
| Regulation of apoptosis and anti-apoptosis signalling by Francisella tularensis. | Microbes and infection 20100201 |
| Activation of JAK2/STAT3 signaling by osteopontin promotes tumor growth in human breast cancer cells. | Carcinogenesis 20100201 |
| Effects of some modulators on purine nucleoside phosphorylase activity in myocardial tissue. | Scandinavian journal of clinical and laboratory investigation 20100201 |
| Cytochalasin D, LY294002 and olomoucine synergize in promoting death of melanoma cells through activation of caspase-3 and apoptosis. | Melanoma research 20100201 |
| A thallium transport FLIPR-based assay for the identification of KCC2-positive modulators. | Journal of biomolecular screening 20100201 |
| Anaplasma phagocytophilum Ats-1 is imported into host cell mitochondria and interferes with apoptosis induction. | PLoS pathogens 20100201 |
| Octyl Gallate Inhibits ATP-induced Intracellular Calcium Increase in PC12 Cells by Inhibiting Multiple Pathways. | The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20100201 |
| Vital function of PRELI and essential requirement of its LEA motif. | Cell death & disease 20100201 |
| An automated fluorescence videomicroscopy assay for the detection of mitotic catastrophe. | Cell death & disease 20100201 |
| A programmed cell death pathway in the malaria parasite Plasmodium falciparum has general features of mammalian apoptosis but is mediated by clan CA cysteine proteases. | Cell death & disease 20100201 |
| Contribution of gamma-secretase to calcium-mediated cell death. | Neuroscience letters 20100129 |
| The Wilms' tumor suppressor protein WT1 is processed by the serine protease HtrA2/Omi. | Molecular cell 20100129 |
| Tumor necrosis factor-related apoptosis-inducing ligand 1 (TRAIL1) enhances the transition of red blood cells from the larval to adult type during metamorphosis in Xenopus. | Blood 20100128 |
| Pyk2 inhibition of p53 as an adaptive and intrinsic mechanism facilitating cell proliferation and survival. | The Journal of biological chemistry 20100115 |
| Identification and characterisation of 2-aminopyridine inhibitors of checkpoint kinase 2. | Bioorganic & medicinal chemistry 20100115 |
| A role for Chk2 in DNA damage induced mitotic delays in human colorectal cancer cells. | Cell cycle (Georgetown, Tex.) 20100115 |
| Displacement assay for the detection of stabilizers of inactive kinase conformations. | Journal of medicinal chemistry 20100114 |
| Role for X-linked Inhibitor of apoptosis protein upstream of mitochondrial permeabilization. | The Journal of biological chemistry 20100108 |
| Photobleaching-based quantitative analysis of fluorescence resonance energy transfer inside single living cell. | Journal of fluorescence 20100101 |
| Apoptosis and autophagy in rat cerebellar granule neuron death: Role of reactive oxygen species. | Journal of neuroscience research 20100101 |
| Role of AIF in cardiac apoptosis in hypertrophic cardiomyocytes from Dahl salt-sensitive rats. | Cardiovascular research 20100101 |
| Glial cell line-derived neurotrophic factor acutely modulates the excitability of rat small-diameter trigeminal ganglion neurons innervating facial skin. | Brain, behavior, and immunity 20100101 |
| Mammalian Ste20-like protein kinase 3 induces a caspase-independent apoptotic pathway. | The international journal of biochemistry & cell biology 20100101 |
| Identification and characterization of unique proline-rich peptides binding to the mitochondrial fission protein hFis1. | The Journal of biological chemistry 20100101 |
| Modulatory effects of phytoglycoprotein (75 kDa) on allergic inflammatory cytokines in Di(2-ethylhexyl) phthalate (DEHP)-stimulated RBL-2H3 cells. | Journal of cellular biochemistry 20100101 |
| Hsa-mir-125b-2 is highly expressed in childhood ETV6/RUNX1 (TEL/AML1) leukemias and confers survival advantage to growth inhibitory signals independent of p53. | Leukemia 20100101 |
| Antiapoptotic and proliferative effects of low concentrations of 7β-hydroxycholesterol in human endothelial cells via ERK activation. | Journal of vascular research 20100101 |
| A phase I trial of UCN-01 and prednisone in patients with refractory solid tumors and lymphomas. | Cancer chemotherapy and pharmacology 20100101 |
| Conventional protein kinase C plays a critical role in negative regulation of CD98-induced homotypic aggregation. | Tissue antigens 20100101 |
| Pim-1 kinase as activator of the cell cycle pathway in neuronal death induced by DNA damage. | Journal of neurochemistry 20100101 |
| Binding of ATP to nerve growth factor: characterization and relevance for bioactivity. | Neurochemistry international 20100101 |
| The phosphoproteome of Fusarium graminearum at the onset of nitrogen starvation. | Proteomics 20100101 |
| Enzastaurin induces H2AX phosphorylation to regulate apoptosis via MAPK signalling in malignant glioma cells. | European journal of cancer (Oxford, England : 1990) 20100101 |
| The malaria parasite cyclic GMP-dependent protein kinase plays a central role in blood-stage schizogony. | Eukaryotic cell 20100101 |
| High-throughput virtual screening of proteins using GRID molecular interaction fields. | Journal of chemical information and modeling 20100101 |
| 2,4-Diaminopyrimidine MK2 inhibitors. Part I: Observation of an unexpected inhibitor binding mode. | Bioorganic & medicinal chemistry letters 20100101 |
| Protein kinase Calpha: disease regulator and therapeutic target. | Trends in pharmacological sciences 20100101 |
| Microbial alkaloid staurosporine induces formation of nanometer-wide membrane tubular extensions (cytonemes, membrane tethers) in human neutrophils. | Cell adhesion & migration 20100101 |
| Sensitivity of staurosporine-induced differentiated RGC-5 cells to homocysteine. | Current eye research 20100101 |
| Monocyte derivatives promote angiogenesis and myocyte survival in a model of myocardial infarction. | Cell transplantation 20100101 |
| Prolyl hydroxylases 2 and 3 act in gliomas as protective negative feedback regulators of hypoxia-inducible factors. | Cancer research 20100101 |
| Sonic Hedgehog gene delivery to the rodent heart promotes angiogenesis via iNOS/netrin-1/PKC pathway. | PloS one 20100101 |
| miR-30 regulates mitochondrial fission through targeting p53 and the dynamin-related protein-1 pathway. | PLoS genetics 20100101 |
| XIAP is not required for human tumor cell survival in the absence of an exogenous death signal. | BMC cancer 20100101 |
| The identification of markers of macrophage differentiation in PMA-stimulated THP-1 cells and monocyte-derived macrophages. | PloS one 20100101 |
| Adaptation of NS cells growth and differentiation to high-throughput screening-compatible plates. | BMC neuroscience 20100101 |
| TNF-alpha mediates eosinophil cationic protein-induced apoptosis in BEAS-2B cells. | BMC cell biology 20100101 |
| Delineation of downstream signalling components during acrosome reaction mediated by heat solubilized human zona pellucida. | Reproductive biology and endocrinology : RB&E 20100101 |
| New Strategy of Functional Analysis of PHGPx Knockout Mice Model Using Transgenic Rescue Method and Cre-LoxP System. | Journal of clinical biochemistry and nutrition 20100101 |
| The mitochondria-independent cytotoxic effect of nelfinavir on leukemia cells can be enhanced by sorafenib-mediated mcl-1 downregulation and mitochondrial membrane destabilization. | Molecular cancer 20100101 |
| Transcriptome analysis reveals absence of unintended effects in drought-tolerant transgenic plants overexpressing the transcription factor ABF3. | BMC genomics 20100101 |
| Galanin protects against intracellular amyloid toxicity in human primary neurons. | Journal of Alzheimer's disease : JAD 20100101 |
| Diffusion is capable of translating anisotropic apoptosis initiation into a homogeneous execution of cell death. | BMC systems biology 20100101 |
| NSC114792, a novel small molecule identified through structure-based computational database screening, selectively inhibits JAK3. | Molecular cancer 20100101 |
| Sindbis viral vector induced apoptosis requires translational inhibition and signaling through Mcl-1 and Bak. | Molecular cancer 20100101 |
| Upregulation of cytoplasmic gelsolin, an amyloid-beta-binding protein, under oxidative stress conditions: involvement of protein kinase C. | Journal of Alzheimer's disease : JAD 20100101 |
| Tau dephosphorylation potentiates apoptosis by mechanisms involving a failed dephosphorylation/activation of Bcl-2. | Journal of Alzheimer's disease : JAD 20100101 |
| Posttranslational modifications, localization, and protein interactions of optineurin, the product of a glaucoma gene. | PloS one 20100101 |
| Human cytomegaloviruses expressing yellow fluorescent fusion proteins--characterization and use in antiviral screening. | PloS one 20100101 |
| Presenilin-1 holoprotein is an interacting partner of sarco endoplasmic reticulum calcium-ATPase and confers resistance to endoplasmic reticulum stress. | Journal of Alzheimer's disease : JAD 20100101 |
| Acute NMDA toxicity in cultured rat cerebellar granule neurons is accompanied by autophagy induction and late onset autophagic cell death phenotype. | BMC neuroscience 20100101 |
| Vacuolar ATPase regulates surfactant secretion in rat alveolar type II cells by modulating lamellar body calcium. | PloS one 20100101 |
| Mechanisms of ER Stress-Mediated Mitochondrial Membrane Permeabilization. | International journal of cell biology 20100101 |
| Pyk2 uncouples metabotropic glutamate receptor G protein signaling but facilitates ERK1/2 activation. | Molecular brain 20100101 |
| Signal transduction, receptors, mediators and genes: younger than ever - the 13th meeting of the Signal Transduction Society focused on aging and immunology. | Cell communication and signaling : CCS 20100101 |
| Cellular stress responses: cell survival and cell death. | International journal of cell biology 20100101 |
| BRCA1 as a Therapeutic Target in Sporadic Epithelial Ovarian Cancer. | Journal of oncology 20100101 |
| N-nitroso-N-methylurea and N-nitroso-N-ethylurea induce upregulation of cellular NF-kappa B activity through protein kinase C-dependent pathway in human malignant keratinocytes. | Archives of pharmacal research 20100101 |
| miR-24 regulates apoptosis by targeting the open reading frame (ORF) region of FAF1 in cancer cells. | PloS one 20100101 |
| Different pathways lead to mitochondrial fragmentation during apoptotic and excitotoxic cell death in primary neurons. | Journal of biochemical and molecular toxicology 20100101 |
| Histone deacetylase inhibitor vorinostat suppresses the growth of uterine sarcomas in vitro and in vivo. | Molecular cancer 20100101 |
| Cell-free-based protein microarray technology using agarose/DNA microplate. | Methods in molecular biology (Clifton, N.J.) 20100101 |
| Trisubstituted purines are useful tools for developing potent plant mitogen-activated protein kinase inhibitors. | Bioscience, biotechnology, and biochemistry 20100101 |
| CNTF induces regeneration of cone outer segments in a rat model of retinal degeneration. | PloS one 20100101 |
| Systematic analysis of genome-wide fitness data in yeast reveals novel gene function and drug action. | Genome biology 20100101 |
| A GIP receptor agonist exhibits beta-cell anti-apoptotic actions in rat models of diabetes resulting in improved beta-cell function and glycemic control. | PloS one 20100101 |
| Regulation of proapoptotic mammalian ste20-like kinase MST2 by the IGF1-Akt pathway. | PloS one 20100101 |
| A novel analytical framework for dissecting the genetic architecture of behavioral symptoms in neuropsychiatric disorders. | PloS one 20100101 |
| Dopamine neuron stimulating actions of a GDNF propeptide. | PloS one 20100101 |
| Cytosolic Hsp60 is involved in the NF-kappaB-dependent survival of cancer cells via IKK regulation. | PloS one 20100101 |
| Induction of autophagy by cystatin C: a mechanism that protects murine primary cortical neurons and neuronal cell lines. | PloS one 20100101 |
| Stress-induced sphingolipid signaling: role of type-2 neutral sphingomyelinase in murine cell apoptosis and proliferation. | PloS one 20100101 |
| Bax inhibitor-1 down-regulation in the progression of chronic liver diseases. | BMC gastroenterology 20100101 |
| TNFalpha induces choroid plexus epithelial cell barrier alterations by apoptotic and nonapoptotic mechanisms. | Journal of biomedicine & biotechnology 20100101 |
| Molecular mechanisms of acquired resistance to tyrosine kinase targeted therapy. | Molecular cancer 20100101 |
| Anti-parasitic compounds from Streptomyces sp. strains isolated from Mediterranean sponges. | Marine drugs 20100101 |
| Synthesis and antitumor activity of bisindolylmaleimide and amino acid ester conjugates. | Journal of Asian natural products research 20100101 |
| A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction. | BMC bioinformatics 20100101 |
| Differential sensitivity of melanoma cell lines with BRAFV600E mutation to the specific Raf inhibitor PLX4032. | Journal of translational medicine 20100101 |
| Inhibition of nitric oxide (NO) production in lipopolysaccharide (LPS)-activated murine macrophage RAW 264.7 cells by the norsesterterpene peroxide, epimuqubilin A. | Marine drugs 20100101 |
| Novel anti-infective compounds from marine bacteria. | Marine drugs 20100101 |
| Tau overexpression inhibits cell apoptosis with the mechanisms involving multiple viability-related factors. | Journal of Alzheimer's disease : JAD 20100101 |
| [Novel compounds increasing chaperone Hsp70 expression and their biological activity]. | Tsitologiia 20100101 |
| Microarray analysis of Shigella flexneri-infected epithelial cells identifies host factors important for apoptosis inhibition. | BMC genomics 20100101 |
| HSP60, a protein downregulated by IGFBP7 in colorectal carcinoma. | Journal of experimental & clinical cancer research : CR 20100101 |
| Transient signaling of Erk1/2, Akt and PLCgamma induced by nerve growth factor in brain capillary endothelial cells. | Vascular pharmacology 20100101 |
| A natural compound from Hydnophytum formicarium induces apoptosis of MCF-7 cells via up-regulation of Bax. | Cancer cell international 20100101 |
| Metastasis-inducing S100A4 and RANTES cooperate in promoting tumor progression in mice. | PloS one 20100101 |
| Novel protein kinase D inhibitors cause potent arrest in prostate cancer cell growth and motility. | BMC chemical biology 20100101 |
| Secreted Mycobacterium tuberculosis Rv3654c and Rv3655c proteins participate in the suppression of macrophage apoptosis. | PloS one 20100101 |
| MUC1-associated proliferation signature predicts outcomes in lung adenocarcinoma patients. | BMC medical genomics 20100101 |
| Interference with activator protein-2 transcription factors leads to induction of apoptosis and an increase in chemo- and radiation-sensitivity in breast cancer cells. | BMC cancer 20100101 |
| Incorporation of podoplanin into HIV released from HEK-293T cells, but not PBMC, is required for efficient binding to the attachment factor CLEC-2. | Retrovirology 20100101 |
| The stem cell marker CD133 associates with enhanced colony formation and cell motility in colorectal cancer. | PloS one 20100101 |
| Signal transduction mechanisms involved in S100A4-induced activation of the transcription factor NF-kappaB. | BMC cancer 20100101 |
| Cell-free expression of protein kinase a for rapid activity assays. | Analytical chemistry insights 20100101 |
| Optical scatter microscopy based on two-dimensional Gabor filters. | Journal of visualized experiments : JoVE 20100101 |
| Vicrostatin - an anti-invasive multi-integrin targeting chimeric disintegrin with tumor anti-angiogenic and pro-apoptotic activities. | PloS one 20100101 |
| Cell cycle and anti-estrogen effects synergize to regulate cell proliferation and ER target gene expression. | PloS one 20100101 |
| Phosphorylation State-Dependent High Throughput Screening of the c-Met Kinase. | Current chemical genomics 20100101 |
| 14-3-3epsilon contributes to tumour suppression in laryngeal carcinoma by affecting apoptosis and invasion. | BMC cancer 20100101 |
| Blockade of TRPM7 channel activity and cell death by inhibitors of 5-lipoxygenase. | PloS one 20100101 |
| Kinome-wide interaction modelling using alignment-based and alignment-independent approaches for kinase description and linear and non-linear data analysis techniques. | BMC bioinformatics 20100101 |
| Dasatinib reverses cancer-associated fibroblasts (CAFs) from primary lung carcinomas to a phenotype comparable to that of normal fibroblasts. | Molecular cancer 20100101 |
| Analysis of inhibitor of apoptosis protein family expression during mammary gland development. | BMC developmental biology 20100101 |
| JAK2 V617F constitutive activation requires JH2 residue F595: a pseudokinase domain target for specific inhibitors. | PloS one 20100101 |
| Bryostatin modulates latent HIV-1 infection via PKC and AMPK signaling but inhibits acute infection in a receptor independent manner. | PloS one 20100101 |
| Breast carcinoma cells re-express E-cadherin during mesenchymal to epithelial reverting transition. | Molecular cancer 20100101 |
| Asc1 supports cell-wall integrity near bud sites by a Pkc1 independent mechanism. | PloS one 20100101 |
| The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways. | Genome biology and evolution 20100101 |
| Functional expression and intracellular signaling of UTP-sensitive P2Y receptors in theca-interstitial cells. | Reproductive biology and endocrinology : RB&E 20100101 |
| Deoxygedunin, a natural product with potent neurotrophic activity in mice. | PloS one 20100101 |
| A novel cell-free mitochondrial fusion assay amenable for high-throughput screenings of fusion modulators. | BMC biology 20100101 |
| Polycyclic aromatic hydrocarbon components contribute to the mitochondria-antiapoptotic effect of fine particulate matter on human bronchial epithelial cells via the aryl hydrocarbon receptor. | Particle and fibre toxicology 20100101 |
| Down-regulation of GRP78 in human glaucomatous trabecular meshwork cells. | Molecular vision 20100101 |
| Endocytosis of MPO in marginal cells is regulated by PKC, protein phosphatase, ERK and PI3-K signaling cascades, but not by PKA and MEK signaling cascades. | ORL; journal for oto-rhino-laryngology and its related specialties 20100101 |
| MiR-145, a new regulator of the DNA fragmentation factor-45 (DFF45)-mediated apoptotic network. | Molecular cancer 20100101 |
| Molecular basis for defect in Alix-binding by alternatively spliced isoform of ALG-2 (ALG-2DeltaGF122) and structural roles of F122 in target recognition. | BMC structural biology 20100101 |
| Cellular apoptosis susceptibility (CSE1L/CAS) protein in cancer metastasis and chemotherapeutic drug-induced apoptosis. | Journal of experimental & clinical cancer research : CR 20100101 |
| UV-B induced transcript accumulation of DAHP synthase in suspension-cultured Catharanthus roseus cells. | Journal of molecular signaling 20100101 |
| Menthol response and adaptation in nociceptive-like and nonnociceptive-like neurons: role of protein kinases. | Molecular pain 20100101 |
| Structural comparison of human mammalian ste20-like kinases. | PloS one 20100101 |
| Multidrug resistance protein transporter and Ins(1,4,5)P₃-sensitive Ca²+-signaling involved in adenosine triphosphate export via Gq protein-coupled NK₂-receptor stimulation with neurokinin A. | Journal of pharmacological sciences 20100101 |
| The haematopoietic GTPase RhoH modulates IL3 signalling through regulation of STAT activity and IL3 receptor expression. | Molecular cancer 20100101 |
| Regulation of HuR by DNA Damage Response Kinases. | Journal of nucleic acids 20100101 |
| [Changes in K+, Na+ and Cl- contents and K+ and Cl- fluxes during apoptosis of U937 cells by staurosporine. On the mechanism of cell dehydration in apoptosis]. | Tsitologiia 20100101 |
| [Computation of the K+, Na+ and Cl- fluxes through plasma membrane of animal cell with Na+/K+ pump, NKCC, NC cotransporters, and ionic channels with and without non-Goldman rectification in K+ channels. Norma and apoptosis]. | Tsitologiia 20100101 |
| Binding of protein kinase inhibitors to synapsin I inferred from pair-wise binding site similarity measurements. | PloS one 20100101 |
| Distinct patterns of DNA damage response and apoptosis correlate with Jak/Stat and PI3kinase response profiles in human acute myelogenous leukemia. | PloS one 20100101 |
| The non-pathogenic mycobacteria M. smegmatis and M. fortuitum induce rapid host cell apoptosis via a caspase-3 and TNF dependent pathway. | BMC microbiology 20100101 |
| The nontoxic natural compound Curcumin exerts anti-proliferative, anti-migratory, and anti-invasive properties against malignant gliomas. | BMC cancer 20100101 |
| Phosphorylation of HOX11/TLX1 on Threonine-247 during mitosis modulates expression of cyclin B1. | Molecular cancer 20100101 |
| Cytotoxicity screening of Bangladeshi medicinal plant extracts on pancreatic cancer cells. | BMC complementary and alternative medicine 20100101 |
| Transduction of human EPO into human bone marrow mesenchymal stromal cells synergistically enhances cell-protective and migratory effects. | Molekuliarnaia biologiia 20100101 |
| Protease activated receptors 1 and 4 sensitize TRPV1 in nociceptive neurones. | Molecular pain 20100101 |
| Short-hairpin RNA-induced suppression of adenine nucleotide translocase-2 in breast cancer cells restores their susceptibility to TRAIL-induced apoptosis by activating JNK and modulating TRAIL receptor expression. | Molecular cancer 20100101 |
| Hairless expression attenuates apoptosis in a mouse model and the COS cell line; involvement of p53. | PloS one 20100101 |
| Brain mitochondrial dysfunction in aging, neurodegeneration, and Parkinson's disease. | Frontiers in aging neuroscience 20100101 |
| Quercetin prevents progression of disease in elastase/LPS-exposed mice by negatively regulating MMP expression. | Respiratory research 20100101 |
| Parameters of Reserpine Analogs That Induce MSH2/MSH6-Dependent Cytotoxic Response. | Journal of nucleic acids 20100101 |
| Anti-apoptotic effect of claudin-1 in tamoxifen-treated human breast cancer MCF-7 cells. | BMC cancer 20100101 |
| Mechanisms of cell death in canine parvovirus-infected cells provide intuitive insights to developing nanotools for medicine. | International journal of nanomedicine 20100101 |
| Interleukins, laminin and Epstein - Barr virus latent membrane protein 1 (EBV LMP1) promote metastatic phenotype in nasopharyngeal carcinoma. | BMC cancer 20100101 |
| Yokukansan inhibits neuronal death during ER stress by regulating the unfolded protein response. | PloS one 20100101 |
| Novel HTS strategy identifies TRAIL-sensitizing compounds acting specifically through the caspase-8 apoptotic axis. | PloS one 20100101 |
| Phospholipase D promotes Arcanobacterium haemolyticum adhesion via lipid raft remodeling and host cell death following bacterial invasion. | BMC microbiology 20100101 |
| Bevacizumab neutralizes the protective effect of vascular endothelial growth factor on retinal ganglion cells. | Molecular vision 20100101 |
| Functional characterization of FLT3 receptor signaling deregulation in acute myeloid leukemia by single cell network profiling (SCNP). | PloS one 20100101 |
| The roles of BDNF, pCREB and Wnt3a in the latent period preceding activation of progenitor cell mitosis in the adult dentate gyrus by fluoxetine. | PloS one 20100101 |
| Generation and characterization of the Anp32e-deficient mouse. | PloS one 20100101 |
| Cell type-specific neuroprotective activity of untranslocated prion protein. | PloS one 20100101 |
| Apoptotic markers in protozoan parasites. | Parasites & vectors 20100101 |
| NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration. | Molecular neurodegeneration 20100101 |
| Investigating the evolution of apoptosis in malaria parasites: the importance of ecology. | Parasites & vectors 20100101 |
| Targeting essential pathways in trypanosomatids gives insights into protozoan mechanisms of cell death. | Parasites & vectors 20100101 |
| Von willebrand factor increases endothelial cell adhesiveness for human mesenchymal stem cells by activating p38 mitogen-activated protein kinase. | Stem cell research & therapy 20100101 |
| Investigation of the eIF2alpha phosphorylation mechanism in response to proteasome inhibition in melanoma and breast cancer cells. | Molekuliarnaia biologiia 20100101 |
| A bio-analytical system for rapid cellular electrophysiological assays. | Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20100101 |
| Immense essence of excellence: marine microbial bioactive compounds. | Marine drugs 20100101 |
| Functional identification of neuroprotective molecules. | PloS one 20100101 |
| Role of cellular caspases, nuclear factor-kappa B and interferon regulatory factors in Bluetongue virus infection and cell fate. | Virology journal 20100101 |
| Functional cooperation of of IL-1β and RGS4 in the brachial plexus avulsion mediated brain reorganization. | Journal of brachial plexus and peripheral nerve injury 20100101 |
| Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase. | BMC cancer 20100101 |
| Calcium and neurogenesis in Alzheimer's disease. | Frontiers in neuroscience 20100101 |
| pp32 (ANP32A) expression inhibits pancreatic cancer cell growth and induces gemcitabine resistance by disrupting HuR binding to mRNAs. | PloS one 20100101 |
| Acetaminophen induces apoptosis in rat cortical neurons. | PloS one 20100101 |
| Why do oligodendrocyte lineage cells express glutamate receptors? | F1000 biology reports 20100101 |
| Phosphorylation meets nuclear import: a review. | Cell communication and signaling : CCS 20100101 |
| A serum factor induces insulin-independent translocation of GLUT4 to the cell surface which is maintained in insulin resistance. | PloS one 20100101 |
| Caspase-3 is transiently activated without cell death during early antigen driven expansion of CD8(+) T cells in vivo. | PloS one 20100101 |
| Prion protein misfolding affects calcium homeostasis and sensitizes cells to endoplasmic reticulum stress. | PloS one 20100101 |
| Formation and toxicity of soluble polyglutamine oligomers in living cells. | PloS one 20100101 |
| A rapid, inexpensive high throughput screen method for neurite outgrowth. | Current chemical genomics 20100101 |
| Imaging multiple phases of neurodegeneration: a novel approach to assessing cell death in vivo. | Cell death & disease 20100101 |
| Role of the mitochondrion in programmed necrosis. | Frontiers in physiology 20100101 |
| Taking a back seat: synaptic vesicle clustering in presynaptic terminals. | Frontiers in synaptic neuroscience 20100101 |
| Topical alpha-selective p38 MAP kinase inhibition reduces acute skin inflammation in guinea pig. | Journal of inflammation research 20100101 |
| Primary WWOX phosphorylation and JNK activation during etoposide induces cytotoxicity in HEK293 cells. | Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20100101 |
| The Role of p66shc in Oxidative Stress and Apoptosis. | Acta naturae 20100101 |
| Fibroblast growth factor 2 requires complex formation with ATP for neuroprotective activity. | Neuroscience 20091229 |
| Dependence of leucine-rich repeat kinase 2 (LRRK2) kinase activity on dimerization. | The Journal of biological chemistry 20091225 |
| The alpha-secretase-derived N-terminal product of cellular prion, N1, displays neuroprotective function in vitro and in vivo. | The Journal of biological chemistry 20091218 |
| Activating mutations in TOR are in similar structures as oncogenic mutations in PI3KCalpha. | ACS chemical biology 20091218 |
| A novel pro-apoptotic function of RACK1: suppression of Src activity in the intrinsic and Akt pathways. | Oncogene 20091217 |
| Identification of proapoptotic Bim as a tumor suppressor in neoplastic mast cells: role of KIT D816V and effects of various targeted drugs. | Blood 20091217 |
| Growth-inhibitory effects of four tyrosine kinase inhibitors on neoplastic feline mast cells exhibiting a Kit exon 8 ITD mutation. | Veterinary immunology and immunopathology 20091215 |
| Forced cytochrome B gene mutation expression induces mitochondrial proliferation and prevents apoptosis in human uroepithelial SV-HUC-1 cells. | International journal of cancer 20091215 |
| Preventing Ataxin-3 protein cleavage mitigates degeneration in a Drosophila model of SCA3. | Human molecular genetics 20091215 |
| Structural insights into IKKbeta inhibition by natural products staurosporine and quercetin. | Bioorganic & medicinal chemistry letters 20091215 |
| (3R,5S,7as)-(3,5-Bis(4-fluorophenyl)tetrahydro-1H-oxazolo[3,4-c]oxazol-7a-yl)methanol, a novel neuroprotective agent. | Journal of medicinal chemistry 20091210 |
| Regulation of extracellular matrix genes by arecoline in primary gingival fibroblasts requires epithelial factors. | Journal of periodontal research 20091201 |
| Apoptotic DNA fragmentation can be revealed in situ: an ultrastructural approach. | Microscopy research and technique 20091201 |
| Role of oxidative stress and JNK pathway in apoptotic death induced by potassium deprivation and staurosporine in cerebellar granule neurons. | Neurochemistry international 20091201 |
| Site-specifically phosphorylated forms of H1.5 and H1.2 localized at distinct regions of the nucleus are related to different processes during the cell cycle. | Chromosoma 20091201 |
| XIAP associates with GSK3 and inhibits the promotion of intrinsic apoptotic signaling by GSK3. | Cellular signalling 20091201 |
| The role of survivin in the resistance of endometriotic stromal cells to drug-induced apoptosis. | Human reproduction (Oxford, England) 20091201 |
| K(bg) and Kv1.3 channels mediate potassium efflux in the early phase of apoptosis in Jurkat T lymphocytes. | American journal of physiology. Cell physiology 20091201 |
| Structural basis for the inhibitor recognition of human Lyn kinase domain. | Bioorganic & medicinal chemistry letters 20091201 |
| The role of protein kinase C in the synergistic interaction of safingol and irinotecan in colon cancer cells. | International journal of oncology 20091201 |
| Neurotensin receptor-2 and -3 are crucial for the anti-apoptotic effect of neurotensin on pancreatic beta-TC3 cells. | The international journal of biochemistry & cell biology 20091201 |
| PDK1 regulates chemotaxis in human neutrophils. | Journal of dental research 20091201 |
| NOA36/ZNF330 is a conserved cystein-rich protein with proapoptotic activity in human cells. | Biochimica et biophysica acta 20091201 |
| Detailed NMR, including 1,1-ADEQUATE, and anticancer studies of compounds from the echinoderm Colobometra perspinosa. | Marine drugs 20091201 |
| Marine pyrrolocarbazoles and analogues: synthesis and kinase inhibition. | Marine drugs 20091201 |
| Positive inotropic effect of PHR0007 (2-(4-(4-(Benzyloxy)-3-methoxybenzyl)piperazin-1-)-N-(1-methyl-4,5-dihydro[1,2,4]triazolo[4,3-a]quinolin-7-yl)acetamide) on atrial dynamics in beating rabbit atria. | Drug discoveries & therapeutics 20091201 |
| Neuroprotection against staurosporine by metalloporphyrins independent of antioxidant capability. | Neuroscience letters 20091127 |
| Prostaglandin EP3 receptor superactivates adenylyl cyclase via the Gq/PLC/Ca2+ pathway in a lipid raft-dependent manner. | Biochemical and biophysical research communications 20091127 |
| Role of p53/FAK association and p53Ser46 phosphorylation in staurosporine-mediated apoptosis: wild type versus mutant p53-R175H. | FEBS letters 20091119 |
| Mcl-1-mediated impairment of the intrinsic apoptosis pathway in circulating neutrophils from critically ill patients can be overcome by Fas stimulation. | Journal of immunology (Baltimore, Md. : 1950) 20091115 |
| Constitutive activation of the DNA damage signaling pathway in acute myeloid leukemia with complex karyotype: potential importance for checkpoint targeting therapy. | Cancer research 20091115 |
| Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis. | Molecular cell 20091113 |
| Kinetic mechanism and inhibitor characterization of WNK1 kinase. | Biochemistry 20091103 |
| Different mechanisms of NMDA-mediated protection against neuronal apoptosis: a stimuli-dependent effect. | Neurochemical research 20091101 |
| Attenuated suppression of the oxidative burst by cells dying in the presence of oxidized low density lipoprotein. | Journal of lipid research 20091101 |
| Staurosporine induces apoptosis in human papillomavirus positive oral cancer cells at G2/M phase by disrupting mitochondrial membrane potential and modulation of cell cytoskeleton. | Oral oncology 20091101 |
| GM-CSF regulates the ERK1/2 pathways and protects injured retinal ganglion cells from induced death. | Experimental eye research 20091101 |
| Phosphorylation at S384 regulates the activity of the TaALMT1 malate transporter that underlies aluminum resistance in wheat. | The Plant journal : for cell and molecular biology 20091101 |
| Effects of calcium signaling on Plasmodium falciparum erythrocyte invasion and post-translational modification of gliding-associated protein 45 (PfGAP45). | Molecular and biochemical parasitology 20091101 |
| Mitochondrial DNA depletion promotes impaired oxidative status and adaptive resistance to apoptosis in T47D breast cancer cells. | European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20091101 |
| SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20091101 |
| The RY/Sph element mediates transcriptional repression of maturation genes from late maturation to early seedling growth. | The New phytologist 20091101 |
| FLT3 inhibition as a targeted therapy for acute myeloid leukemia. | Current opinion in oncology 20091101 |
| Activation of the extrinsic apoptotic pathway by TNF-alpha in human salivary gland (HSG) cells in vitro, suggests a role for the TNF receptor (TNF-R) and intercellular adhesion molecule-1 (ICAM-1) in Sjögren's syndrome-associated autoimmune sialadenitis. | Archives of oral biology 20091101 |
| Neurotrophin signaling through tropomyosin receptor kinases contributes to survival and proliferation of non-Hodgkin lymphoma. | Experimental hematology 20091101 |
| Airway smooth muscle chemokine receptor expression and function in asthma. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20091101 |
| Multiple alphaII-spectrin breakdown products distinguish calpain and caspase dominated necrotic and apoptotic cell death pathways. | Apoptosis : an international journal on programmed cell death 20091101 |
| Midostaurin (PKC412) inhibits immunoglobulin E-dependent activation and mediator release in human blood basophils and mast cells. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20091101 |
| Radiotherapy in conjunction with 7-hydroxystaurosporine: a multimodal approach with tumor pO2 as a potential marker of therapeutic response. | Radiation research 20091101 |
| [The effect of matrine on the signal transduction pathway of transforming growth factor-beta1 in human lung fibroblast cells]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20091101 |
| Suppression of p38 MAPK and JNK via Akt-mediated inhibition of apoptosis signal-regulating kinase 1 constitutes a core component of the beta-cell pro-survival effects of glucose-dependent insulinotropic polypeptide. | The Journal of biological chemistry 20091030 |
| RNA-specific adenosine deaminase ADAR1 suppresses measles virus-induced apoptosis and activation of protein kinase PKR. | The Journal of biological chemistry 20091023 |
| DNA synthesis of rat bone marrow mesenchymal stem cells through alpha1-adrenergic receptors. | Archives of biochemistry and biophysics 20091015 |
| Apoptotic inducers activate the release of D-aspartate through a hypotonic stimulus-triggered mechanism in PC12 cells. | Archives of biochemistry and biophysics 20091015 |
| Natural product leads for drug discovery: isolation, synthesis and biological evaluation of 6-cyano-5-methoxyindolo[2,3-a]carbazole based ligands as antibacterial agents. | Bioorganic & medicinal chemistry 20091015 |
| ARTEMIS nuclease facilitates apoptotic chromatin cleavage. | Cancer research 20091015 |
| MAC inhibitors suppress mitochondrial apoptosis. | The Biochemical journal 20091012 |
| Effects of ketamine on glucose uptake by glucose transporter type 3 expressed in Xenopus oocytes: The role of protein kinase C. | Biochemical and biophysical research communications 20091009 |
| Activation of the TRPV4 ion channel is enhanced by phosphorylation. | The Journal of biological chemistry 20091009 |
| Interferon-resistant Daudi cell line with a Stat2 defect is resistant to apoptosis induced by chemotherapeutic agents. | The Journal of biological chemistry 20091009 |
| Evidence for potential functionality of nuclearly-encoded humanin isoforms. | Genomics 20091001 |
| Brain-derived neurotrophic factor released from engineered mesenchymal stem cells attenuates glutamate- and hydrogen peroxide-mediated death of staurosporine-differentiated RGC-5 cells. | Experimental eye research 20091001 |
| Ibuprofen-arginine generates nitric oxide and has enhanced anti-inflammatory effects. | Pharmacological research 20091001 |
| Bovine lactadherin as a calcium-independent imaging agent of phosphatidylserine expressed on the surface of apoptotic HeLa cells. | The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20091001 |
| Islet beta-cells deficient in Bcl-xL develop but are abnormally sensitive to apoptotic stimuli. | Diabetes 20091001 |
| Human umbilical cord blood stem cells upregulate matrix metalloproteinase-2 in rats after spinal cord injury. | Neurobiology of disease 20091001 |
| Epidermal growth factor receptor inhibitors promote CNS axon growth through off-target effects on glia. | Neurobiology of disease 20091001 |
| Downregulation of uridine-cytidine kinase like-1 decreases proliferation and enhances tumor susceptibility to lysis by apoptotic agents and natural killer cells. | Apoptosis : an international journal on programmed cell death 20091001 |
| AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML). | Blood 20091001 |
| Mg2+- and MgATP-inhibited and Ca2+/calmodulin-sensitive TRPM7-like current in hepatoma and hepatocytes. | American journal of physiology. Gastrointestinal and liver physiology 20091001 |
| Effects of TRH and its analogues on primary cortical neuronal cell damage induced by various excitotoxic, necrotic and apoptotic agents. | Neuropeptides 20091001 |
| Interaction with checkpoint kinase 1 modulates the recruitment of nucleophosmin to chromatin. | Journal of proteome research 20091001 |
| Novel anti-cancer compounds: structure-based discovery of chemical chaperons for p53. | Oncology reports 20091001 |
| Molecular cloning, sequence analysis and functional characterization of the gene cluster for biosynthesis of K-252a and its analogs. | Molecular bioSystems 20091001 |
| Biochemical characterization and substrate specificity of the gene cluster for biosyntheses of K-252a and its analogs by in vitro heterologous expression system of Escherichia coli. | Molecular bioSystems 20091001 |
| Phosphate-affinity electrophoresis on a microchip for determination of protein kinase activity. | Electrophoresis 20091001 |
| Helicobacter pylori counteracts the apoptotic action of its VacA toxin by injecting the CagA protein into gastric epithelial cells. | PLoS pathogens 20091001 |
| Biosynthesis of indolocarbazole and goadsporin, two different heterocyclic antibiotics produced by actinomycetes. | Bioscience, biotechnology, and biochemistry 20091001 |
| Tristetraprolin: a weapon against HPV-induced cervical cancer? | Aging 20091001 |
| ZBP-89 reduces the cell death threshold in hepatocellular carcinoma cells by increasing caspase-6 and S phase cell cycle arrest. | Cancer letters 20090928 |
| Statin's excitoprotection is mediated by sAPP and the subsequent attenuation of calpain-induced truncation events, likely via rho-ROCK signaling. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090909 |
| Myocyte stress 1 plays an important role in cellular hypertrophy and protection against apoptosis. | FEBS letters 20090903 |
| CFTR regulation of intracellular pH and ceramides is required for lung endothelial cell apoptosis. | American journal of respiratory cell and molecular biology 20090901 |
| Emodin inhibits voltage-dependent potassium current in guinea pig gallbladder smooth muscle. | Basic & clinical pharmacology & toxicology 20090901 |
| Nerve growth factor enhances cough and airway obstruction via TrkA receptor- and TRPV1-dependent mechanisms. | Thorax 20090901 |
| Multiplexed assay panel of cytotoxicity in HK-2 cells for detection of renal proximal tubule injury potential of compounds. | Toxicology in vitro : an international journal published in association with BIBRA 20090901 |
| Staurosporine-induced apoptosis in P388D1 macrophages involves both extrinsic and intrinsic pathways. | Cell biology international 20090901 |
| Mutations in the mitochondrial genome confer resistance of cancer cells to anticancer drugs. | Cancer science 20090901 |
| Alpha A-crystallin and alpha B-crystallin, newly identified interaction proteins of protease-activated receptor-2, rescue astrocytes from C2-ceramide- and staurosporine-induced cell death. | Journal of neurochemistry 20090901 |
| Development and applications of a broad-coverage, TR-FRET-based kinase binding assay platform. | Journal of biomolecular screening 20090901 |
| Oral small-molecule tyrosine kinase inhibitor midostaurin (PKC412) inhibits growth and induces megakaryocytic differentiation in human leukemia cells. | Toxicology in vitro : an international journal published in association with BIBRA 20090901 |
| Methylation of histone H3 lysine 27 associated with apoptosis in osteosarcoma cells induced by staurosporine. | Histology and histopathology 20090901 |
| Structure-based discovery of low molecular weight compounds that stimulate neurite outgrowth and substitute for nerve growth factor. | Journal of neurochemistry 20090901 |
| The C-terminus of interferon gamma receptor beta chain (IFNgammaR2) has antiapoptotic activity as a Bax inhibitor. | Cancer biology & therapy 20090901 |
| Staurosporine tethered peptide ligands that target cAMP-dependent protein kinase (PKA): optimization and selectivity profiling. | Bioorganic & medicinal chemistry 20090901 |
| Guttiferones O and P, prenylated benzophenone MAPKAPK-2 inhibitors from Garcinia solomonensis. | Journal of natural products 20090901 |
| Effect of progesterone on gonococci-induced apoptosis and respiratory burst of human polymorphonuclear leukocytes in vitro. | International journal of dermatology 20090901 |
| Killing of cancer cells by the photoactivatable protein kinase C inhibitor, calphostin C, involves induction of endoplasmic reticulum stress. | Neoplasia (New York, N.Y.) 20090901 |
| PI-3 kinase pathway can mediate the effect of TGF-beta1 in inducing the expression of SHARP-2 in LLC-PK1 cells. | Journal of Zhejiang University. Science. B 20090901 |
| Streptococcus pneumoniae serotype 1 capsular polysaccharide induces CD8CD28 regulatory T lymphocytes by TCR crosslinking. | PLoS pathogens 20090901 |
| Fates of neurotrophins after retrograde axonal transport: phosphorylation of p75NTR is a sorting signal for delayed degradation. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090826 |
| NOX2 mediates apoptotic death induced by staurosporine but not by potassium deprivation in cerebellar granule neurons. | Journal of neuroscience research 20090815 |
| Design, synthesis and biological evaluation of new potent and highly selective ROS1-tyrosine kinase inhibitor. | Bioorganic & medicinal chemistry letters 20090815 |
| Identification of inhibitors of checkpoint kinase 1 through template screening. | Journal of medicinal chemistry 20090813 |
| MLH1 mediates PARP-dependent cell death in response to the methylating agent N-methyl-N-nitrosourea. | British journal of cancer 20090804 |
| Regulation of the apoptosis-inducing kinase DRAK2 by cyclooxygenase-2 in colorectal cancer. | British journal of cancer 20090804 |
| Breast cancer cells expressing stem cell markers CD44+ CD24 lo are eliminated by Numb-1 peptide-activated T cells. | Cancer immunology, immunotherapy : CII 20090801 |
| Cigarette smoke alters respiratory syncytial virus-induced apoptosis and replication. | American journal of respiratory cell and molecular biology 20090801 |
| Activation of the lutropin/choriogonadotropin receptor inhibits apoptosis of immature Leydig cells in primary culture. | Endocrinology 20090801 |
| Suppressive effect of CTB glycoprotein (75 kDa) on IL-4 expression in primary-cultured lymphocytes treated with di(2-ethylhexyl) phthalate. | Naunyn-Schmiedeberg's archives of pharmacology 20090801 |
| Innate immunity turned inside-out: antimicrobial defense by phagocyte extracellular traps. | Journal of molecular medicine (Berlin, Germany) 20090801 |
| Silver ion-induced suicidal erythrocyte death. | Journal of applied toxicology : JAT 20090801 |
| Human RIF1 encodes an anti-apoptotic factor required for DNA repair. | Carcinogenesis 20090801 |
| Orally available Mn porphyrins with superoxide dismutase and catalase activities. | Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20090801 |
| Ca2+-independent contraction of longitudinal ileal smooth muscle is potentiated by a zipper-interacting protein kinase pseudosubstrate peptide. | American journal of physiology. Gastrointestinal and liver physiology 20090801 |
| The G(2) DNA damage checkpoint: could this ancient regulator be the Achilles heel of cancer? | Cancer biology & therapy 20090801 |
| Oxidative stress triggers neuronal caspase-independent death: endonuclease G involvement in programmed cell death-type III. | Cellular and molecular life sciences : CMLS 20090801 |
| Platelet-derived growth factor-receptor alpha strongly inhibits melanoma growth in vitro and in vivo. | Neoplasia (New York, N.Y.) 20090801 |
| Induction of apoptosis by staurosporine involves the inhibition of expression of the major cell cycle proteins at the G(2)/m checkpoint accompanied by alterations in Erk and Akt kinase activities. | Anticancer research 20090801 |
| Nuclear calcium signaling controls expression of a large gene pool: identification of a gene program for acquired neuroprotection induced by synaptic activity. | PLoS genetics 20090801 |
| Yeast glycogen synthase kinase-3beta pathway inhibitors from an organic extract of Streptomyces sp. | Journal of natural products 20090801 |
| Regulation of host translational machinery by African swine fever virus. | PLoS pathogens 20090801 |
| Mitochondrial damage as death inducer in heart-derived H9c2 cells: more than one way for an early demise. | Journal of bioenergetics and biomembranes 20090801 |
| Anti-apoptotic genes in the survival of monocytic cells during infection. | Current genomics 20090801 |
| Inhibition of Akt sensitises neuroblastoma cells to gold(III) porphyrin 1a, a novel antitumour drug induced apoptosis and growth inhibition. | British journal of cancer 20090721 |
| Generation of potent and selective kinase inhibitors by combinatorial biosynthesis of glycosylated indolocarbazoles. | Chemical communications (Cambridge, England) 20090721 |
| Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis. | Journal of cell science 20090715 |
| Vascular endothelial growth factor receptor-3 promotes breast cancer cell proliferation, motility and survival in vitro and tumor formation in vivo. | Cell cycle (Georgetown, Tex.) 20090715 |
| Stem cells downregulate the elevated levels of tissue plasminogen activator in rats after spinal cord injury. | Neurochemical research 20090701 |
| beta-Phorbol ester-induced enhancement of exocytosis in large mossy fiber boutons of mouse hippocampus. | The journal of physiological sciences : JPS 20090701 |
| Palmitoyl protein thioesterase 1 modulates tumor necrosis factor alpha-induced apoptosis. | Biochimica et biophysica acta 20090701 |
| Thymoquinone-induced suicidal erythrocyte death. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090701 |
| A cell wall extract from the endophytic fungus Piriformospora indica promotes growth of Arabidopsis seedlings and induces intracellular calcium elevation in roots. | The Plant journal : for cell and molecular biology 20090701 |
| BDNF-TrkB signaling pathway mediates the induction of epileptiform activity induced by a convulsant drug cyclothiazide. | Neuropharmacology 20090701 |
| Differential effects of treadmill running and wheel running on spatial or aversive learning and memory: roles of amygdalar brain-derived neurotrophic factor and synaptotagmin I. | The Journal of physiology 20090701 |
| Synthesis and biological evaluation of novel 4-azaindolyl-indolyl-maleimides as glycogen synthase kinase-3beta (GSK-3beta) inhibitors. | Bioorganic & medicinal chemistry 20090701 |
| Mechanical dynamics of single cells during early apoptosis. | Cell motility and the cytoskeleton 20090701 |
| On the origins of enzyme inhibitor selectivity and promiscuity: a case study of protein kinase binding to staurosporine. | Chemical biology & drug design 20090701 |
| An involvement of BDNF and PI3-K/Akt in the anti-apoptotic effect of memantine on staurosporine-evoked cell death in primary cortical neurons. | Apoptosis : an international journal on programmed cell death 20090701 |
| Cell cycle kinases as therapeutic targets for cancer. | Nature reviews. Drug discovery 20090701 |
| Programmed cellular necrosis mediated by the pore-forming alpha-toxin from Clostridium septicum. | PLoS pathogens 20090701 |
| Human neurospheres as three-dimensional cellular systems for developmental neurotoxicity testing. | Environmental health perspectives 20090701 |
| Bax Inhibitor-1, a conserved cell death suppressor, is a key molecular switch downstream from a variety of biotic and abiotic stress signals in plants. | International journal of molecular sciences 20090701 |
| Loss of Wip1 sensitizes cells to stress- and DNA damage-induced apoptosis. | The Journal of biological chemistry 20090626 |
| Expression of anti-apoptosis genes alters lactate metabolism of Chinese Hamster Ovary cells in culture. | Biotechnology and bioengineering 20090615 |
| Synthetic staurosporines via a ring closing metathesis strategy as potent JAK3 inhibitors and modulators of allergic responses. | Bioorganic & medicinal chemistry letters 20090615 |
| The apoptotic ring: a novel entity with phosphorylated histones H2AX and H2B and activated DNA damage response kinases. | Cell cycle (Georgetown, Tex.) 20090615 |
| Anaplastic lymphoma kinase: signalling in development and disease. | The Biochemical journal 20090615 |
| Spatiotemporal activation of caspase-dependent and -independent pathways in staurosporine-induced apoptosis of p53wt and p53mt human cervical carcinoma cells. | Biology of the cell 20090604 |
| Organ-specific inhibition of metastatic colon carcinoma by CXCR3 antagonism. | British journal of cancer 20090602 |
| Fragment and knowledge-based design of selective GSK-3beta inhibitors using virtual screening models. | European journal of medicinal chemistry 20090601 |
| Receptor tyrosine kinases regulate alpha1D-adrenoceptor signaling properties: phosphorylation and desensitization. | The international journal of biochemistry & cell biology 20090601 |
| Integrated microfluidic devices for combinatorial cell-based assays. | Biomedical microdevices 20090601 |
| A novel lipid binding protein is a factor required for MgATP stimulation of the squid nerve Na+/Ca2+ exchanger. | Biochimica et biophysica acta 20090601 |
| PINOID kinase regulates root gravitropism through modulation of PIN2-dependent basipetal auxin transport in Arabidopsis. | Plant physiology 20090601 |
| Water taste transduction pathway is calcium dependent in Drosophila. | Chemical senses 20090601 |
| A new screening assay for allosteric inhibitors of cSrc. | Nature chemical biology 20090601 |
| Glycogen synthase kinase-3beta regulates etoposide-induced apoptosis via Bcl-2 mediated caspase-3 activation in C3H10T1/2 cells. | Apoptosis : an international journal on programmed cell death 20090601 |
| Bioactive 5,6-dihydro-alpha-pyrone derivatives from Hyptis brevipes. | Journal of natural products 20090601 |
| Apoptosis gene profiling reveals spatio-temporal regulated expression of the p53/Mdm2 pathway during lens development. | Experimental eye research 20090601 |
| Inducible over-expression of wild type alpha-synuclein in human neuronal cells leads to caspase-dependent non-apoptotic death. | Journal of neurochemistry 20090601 |
| Rapid pathogen-induced apoptosis: a mechanism used by dendritic cells to limit intracellular replication of Legionella pneumophila. | PLoS pathogens 20090601 |
| The mechanism of chemokine receptor 9 internalization triggered by interleukin 2 and interleukin 4. | Cellular & molecular immunology 20090601 |
| DNase gamma-dependent and -independent apoptotic DNA fragmentations in Ramos Burkitt's lymphoma cell line. | Biomedical research (Tokyo, Japan) 20090601 |
| Antitumor compounds from marine actinomycetes. | Marine drugs 20090601 |
| [Effect of Caveolin-1 on growth and apoptosis of human breast carcinoma cell line Hs578T/Dox]. | Ai zheng = Aizheng = Chinese journal of cancer 20090601 |
| P66Shc signals to age. | Aging 20090601 |
| The heat shock protein 27 (Hsp27) operates predominantly by blocking the mitochondrial-independent/extrinsic pathway of cellular apoptosis. | Molecules and cells 20090531 |
| Bcl-2 complexed with Beclin-1 maintains full anti-apoptotic function. | Oncogene 20090528 |
| Synthesis, activity, and pharmacophore development for isatin-beta-thiosemicarbazones with selective activity toward multidrug-resistant cells. | Journal of medicinal chemistry 20090528 |
| Visualization of dopamine transporter trafficking in live neurons by use of fluorescent cocaine analogs. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090527 |
| An impedimetric microelectrode-based array sensor for label-free detection of tau hyperphosphorylation in human cells. | Lab on a chip 20090521 |
| Epithelial-to-mesenchymal transition and resistance to ingenol 3-angelate, a novel protein kinase C modulator, in colon cancer cells. | Cancer research 20090515 |
| A small molecule primes embryonic stem cells for differentiation. | Cell stem cell 20090508 |
| Evaluation of poly(ADP-ribose) polymerase cleavage (cPARP) in ejaculated human sperm fractions after induction of apoptosis. | Fertility and sterility 20090501 |
| Neuroprotection by NGF and BDNF against neurotoxin-exerted apoptotic death in neural stem cells are mediated through Trk receptors, activating PI3-kinase and MAPK pathways. | Neurochemical research 20090501 |
| Vicinity analysis: a methodology for the identification of similar protein active sites. | Journal of molecular modeling 20090501 |
| Effects of phorbol 12-myristate 13-acetate on potassium transport in the red blood cells of frog Rana temporaria. | Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20090501 |
| Measuring and monitoring apoptosis and drug toxicity in HIV patients by ligation-mediated polymerase chain reaction. | Journal of cellular and molecular medicine 20090501 |
| Participation of the human sperm proteasome in the capacitation process and its regulation by protein kinase A and tyrosine kinase. | Biology of reproduction 20090501 |
| Regulation of OPA1-mediated mitochondrial fusion by leucine zipper/EF-hand-containing transmembrane protein-1 plays a role in apoptosis. | Cellular signalling 20090501 |
| Long term oncostatin M treatment induces an osteocyte-like differentiation on osteosarcoma and calvaria cells. | Bone 20090501 |
| Protein kinase C in heart failure: a therapeutic target? | Cardiovascular research 20090501 |
| C-terminal Tensin-like (CTEN) is an oncogene which alters cell motility possibly through repression of E-cadherin in colorectal cancer. | The Journal of pathology 20090501 |
| SCA8 repeat expansion: large CTA/CTG repeat alleles in neurological disorders and functional implications. | Human genetics 20090501 |
| Neural progenitor cell death is induced by extracellular ATP via ligation of P2X7 receptor. | Journal of neurochemistry 20090501 |
| Regulation of PI(3)K/Akt signalling and cellular transformation by inositol polyphosphate 4-phosphatase-1. | EMBO reports 20090501 |
| Rickettsia rickettsii infection protects human microvascular endothelial cells against staurosporine-induced apoptosis by a cIAP(2)-independent mechanism. | The Journal of infectious diseases 20090501 |
| GABAergic striatal neurons exhibit caspase-independent, mitochondrially mediated programmed cell death. | Journal of neurochemistry 20090501 |
| Endothelial cell apoptosis is responsible for the formation of coronary thrombotic atherosclerotic plaques. | The Tohoku journal of experimental medicine 20090501 |
| Differential modulation of TNF-alpha-induced apoptosis by Neisseria meningitidis. | PLoS pathogens 20090501 |
| CD30 expression reveals that culture adaptation of human embryonic stem cells can occur through differing routes. | Stem cells (Dayton, Ohio) 20090501 |
| Melatonin induces mitochondrial-mediated apoptosis in human myeloid HL-60 cells. | Journal of pineal research 20090501 |
| IRAK-4 inhibitors for inflammation. | Current topics in medicinal chemistry 20090501 |
| Calcium overload is essential for the acceleration of staurosporine-induced cell death following neuronal differentiation in PC12 cells. | Experimental & molecular medicine 20090430 |
| Ligand binding to LRP1 transactivates Trk receptors by a Src family kinase-dependent pathway. | Science signaling 20090428 |
| A novel molecular mechanism of primary resistance to FLT3-kinase inhibitors in AML. | Blood 20090423 |
| MPP+ impairs autophagic clearance of alpha-synuclein by impairing the activity of dynein. | Neuroreport 20090422 |
| Peptide microarrays for detailed, high-throughput substrate identification, kinetic characterization, and inhibition studies on protein kinase A. | Analytical biochemistry 20090415 |
| Expression of the P2X7 receptor increases the Ca2+ content of the endoplasmic reticulum, activates NFATc1, and protects from apoptosis. | The Journal of biological chemistry 20090410 |
| Cyclophilin D interacts with Bcl2 and exerts an anti-apoptotic effect. | The Journal of biological chemistry 20090410 |
| Hit to lead account of the discovery of a new class of inhibitors of Pim kinases and crystallographic studies revealing an unusual kinase binding mode. | Journal of medicinal chemistry 20090409 |
| Extracellular, cell-permeable survivin inhibits apoptosis while promoting proliferative and metastatic potential. | British journal of cancer 20090407 |
| The ubiquitination of ribosomal S6 kinases is independent from the mitogen-induced phosphorylation/activation of the kinase. | The international journal of biochemistry & cell biology 20090401 |
| CFTR is activated through stimulation of purinergic P2Y2 receptors. | Pflugers Archiv : European journal of physiology 20090401 |
| Apoptotic endothelial cells demonstrate increased adhesiveness for human mesenchymal stem cells. | Journal of cellular physiology 20090401 |
| FLIM and emission spectral analysis of caspase-3 activation inside single living cell during anticancer drug-induced cell death. | European biophysics journal : EBJ 20090401 |
| Dynamics of outer mitochondrial membrane permeabilization during apoptosis. | Cell death and differentiation 20090401 |
| Cellular response induced by a galactose-specific adhesin of enteroaggregative Escherichia coli in INT-407 cells. | FEMS immunology and medical microbiology 20090401 |
| The 27-kDa heat shock protein confers cytoprotective effects through a beta 2-adrenergic receptor agonist-initiated complex with beta-arrestin. | Molecular pharmacology 20090401 |
| p53-dependent control of cell death by nicastrin: lack of requirement for presenilin-dependent gamma-secretase complex. | Journal of neurochemistry 20090401 |
| Indolocarbazole antitumour compounds by combinatorial biosynthesis. | Current opinion in chemical biology 20090401 |
| Pharmacophore modeling study based on known spleen tyrosine kinase inhibitors together with virtual screening for identifying novel inhibitors. | Bioorganic & medicinal chemistry letters 20090401 |
| Isoform-specific regulation of the Na+ -K+ pump by adenosine in guinea pig ventricular myocytes. | Acta pharmacologica Sinica 20090401 |
| FMS-like tyrosine kinase 3-internal tandem duplication tyrosine kinase inhibitors display a nonoverlapping profile of resistance mutations in vitro. | Cancer research 20090401 |
| Human hnRNP Q re-localizes to cytoplasmic granules upon PMA, thapsigargin, arsenite and heat-shock treatments. | Experimental cell research 20090401 |
| BDNF exerts contrasting effects on peripheral myelination of NGF-dependent and BDNF-dependent DRG neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090401 |
| Zeaxanthin, a retinal carotenoid, protects retinal cells against oxidative stress. | Current eye research 20090401 |
| Fourteen compounds and their derivatives for the treatment of diseases and injuries characterized by reduced neurogenesis and neurodegeneration. Neuronascent, Inc.: WO2007035722. | Expert opinion on therapeutic patents 20090401 |
| Heterogeneity of mitochondria and mitochondrial function within cells as another level of mitochondrial complexity. | International journal of molecular sciences 20090401 |
| Crystal structures of MEK1 binary and ternary complexes with nucleotides and inhibitors. | Biochemistry 20090331 |
| Sciatic nerve conditioned medium depleted of pro-NGF modulates sodium currents and neurite outgrowth in PC12 cells. | Neuroscience 20090317 |
| Dehydroepiandrosterone and neurotrophins favor axonal growth in a sensory neuron-keratinocyte coculture model. | Neuroscience 20090317 |
| Production of chromopyrrolic acid by coexpression of inkOD in a heterologous host Streptomyces albus. | Bioorganic & medicinal chemistry letters 20090315 |
| Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation. | Structure (London, England : 1993) 20090311 |
| Erythrocytic casein kinase II regulates cytoadherence of Plasmodium falciparum-infected red blood cells. | The Journal of biological chemistry 20090306 |
| BH3-only protein Bim more critical than Puma in tyrosine kinase inhibitor-induced apoptosis of human leukemic cells and transduced hematopoietic progenitors carrying oncogenic FLT3. | Blood 20090305 |
| Brain-derived neurotrophic factor inhibits spontaneous inhibitory postsynaptic currents in the rat supraoptic nucleus. | Brain research 20090303 |
| Determination of Poly (ADP-ribose) polymerase (PARP) homologues in human ejaculated sperm and its correlation with sperm maturation. | Fertility and sterility 20090301 |
| Protein and lipid kinase inhibitors as targeted anticancer agents of the Ras/Raf/MEK and PI3K/PKB pathways. | Purinergic signalling 20090301 |
| Kinase inhibitors for the treatment of inflammatory and autoimmune disorders. | Purinergic signalling 20090301 |
| Different protection of K252a and N-acetyl-L-cysteine against amyloid-beta peptide-induced cortical neuron apoptosis involving inhibition of MLK3-MKK7-JNK3 signal cascades. | Journal of neuroscience research 20090301 |
| Minocycline reduces the development of abnormal tau species in models of Alzheimer's disease. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090301 |
| Interleukin-6 promotes 2-deoxyglucose uptake through p44/42 MAPKs activation via Ca2+/PKC and EGF receptor in primary cultured chicken hepatocytes. | Journal of cellular physiology 20090301 |
| Selection of cytotoxicity markers for the screening of new chemical entities in a pharmaceutical context: a preliminary study using a multiplexing approach. | Toxicology in vitro : an international journal published in association with BIBRA 20090301 |
| Small molecules with potent osteogenic-inducing activity in osteoblast cells. | Bioorganic & medicinal chemistry letters 20090301 |
| Indolyl-pyrrolone as a new scaffold for Pim1 inhibitors. | Bioorganic & medicinal chemistry letters 20090301 |
| Iron chelation protects the retinal pigment epithelial cell line ARPE-19 against cell death triggered by diverse stimuli. | Investigative ophthalmology & visual science 20090301 |
| Bis(1H-indol-2-yl)methanones are effective inhibitors of FLT3-ITD tyrosine kinase and partially overcome resistance to PKC412A in vitro. | British journal of haematology 20090301 |
| Phospho-p70S6K/p85S6K and cdc2/cdk1 are novel targets for diffuse large B-cell lymphoma combination therapy. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090301 |
| Proteomic analysis of multidrug-resistance mechanisms in adriamycin-resistant variants of DLKP, a squamous lung cancer cell line. | Proteomics 20090301 |
| Analysis of the chloroplast protein kinase Stt7 during state transitions. | PLoS biology 20090301 |
| A novel role for MAPKAPK2 in morphogenesis during zebrafish development. | PLoS genetics 20090301 |
| Apoptosis induced by acrylamide is suppressed in a 21.5% fat diet through caspase-3-independent pathway in mice testis. | Toxicology mechanisms and methods 20090301 |
| The constitutive activity of the ghrelin receptor attenuates apoptosis via a protein kinase C-dependent pathway. | Molecular and cellular endocrinology 20090227 |
| Synthesis of new aza-analogs of staurosporine, K-252a and rebeccamycin by nucleophilic opening of C2-symmetric bis-aziridines. | Organic & biomolecular chemistry 20090221 |
| hNOA1 interacts with complex I and DAP3 and regulates mitochondrial respiration and apoptosis. | The Journal of biological chemistry 20090220 |
| Mechanogenetic coupling of Hydra symmetry breaking and driven Turing instability model. | Biophysical journal 20090218 |
| Time-dependent segmentation of BrdU-signal leads to late detection problems in studies using BrdU as cell label or proliferation marker. | Journal of neuroscience methods 20090215 |
| The neuroprotective action of the mood stabilizing drugs lithium chloride and sodium valproate is mediated through the up-regulation of the homeodomain protein Six1. | Toxicology and applied pharmacology 20090215 |
| Bad targets the permeability transition pore independent of Bax or Bak to switch between Ca2+-dependent cell survival and death. | Molecular cell 20090213 |
| Voltage-dependent anion channel 1-based peptides interact with hexokinase to prevent its anti-apoptotic activity. | The Journal of biological chemistry 20090206 |
| Inactivation of the human vitamin D receptor by caspase-3. | Endocrinology 20090201 |
| Extracts of Cynomorium songaricum protect SK-N-SH human neuroblastoma cells against staurosporine-induced apoptosis potentially through their radical scavenging activity. | Phytotherapy research : PTR 20090201 |
| Inhibitory effects of the antiepileptic drug ethosuximide on G protein-activated inwardly rectifying K+ channels. | Neuropharmacology 20090201 |
| TGFbeta protects mesoangioblasts from apoptosis via sphingosine kinase-1 regulation. | Cellular signalling 20090201 |
| Role of HIF-1alpha and VEGF in human mesenchymal stem cell proliferation by 17beta-estradiol: involvement of PKC, PI3K/Akt, and MAPKs. | American journal of physiology. Cell physiology 20090201 |
| Co-clustering of Golgi complex and other cytoplasmic organelles to crescentic region of half-moon nuclei during apoptosis. | Cell biology international 20090201 |
| A simultaneous release of SOD1 with cytochrome c regulates mitochondria-dependent apoptosis. | Molecular and cellular biochemistry 20090201 |
| Structural insights into the inhibited states of the Mer receptor tyrosine kinase. | Journal of structural biology 20090201 |
| Recruitment of mitochondria into apoptotic signaling correlates with the presence of inclusions formed by amyotrophic lateral sclerosis-associated SOD1 mutations. | Journal of neurochemistry 20090201 |
| Regulation of human organic anion transporter 1 by ANG II: involvement of protein kinase Calpha. | American journal of physiology. Endocrinology and metabolism 20090201 |
| Isolation, structure elucidation and cytotoxic evaluation of endiandrin B from the Australian rainforest plant Endiandra anthropophagorum. | Bioorganic & medicinal chemistry 20090201 |
| Pro-protein convertase-2/carboxypeptidase-E mediated neuropeptide processing of RGC-5 cell after in vitro ischemia. | Neuroscience bulletin 20090201 |
| Silencing of cytosolic NADP(+)-dependent isocitrate dehydrogenase by small interfering RNA enhances the sensitivity of HeLa cells toward staurosporine. | Free radical research 20090201 |
| Steroid hormone control of cell death and cell survival: molecular insights using RNAi. | PLoS genetics 20090201 |
| Atonal homolog 1 is a tumor suppressor gene. | PLoS biology 20090201 |
| Expression of adrenomedullin in human ovaries, ovarian sex cord-stromal tumors and cultured granulosa-luteal cells. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20090201 |
| Mitochondrial DNA instability and metabolic shift in human cancers. | International journal of molecular sciences 20090201 |
| Caspases indirectly regulate cleavage of the mitochondrial fusion GTPase OPA1 in neurons undergoing apoptosis. | Brain research 20090123 |
| Identification of compounds that inhibit the kinase activity of leucine-rich repeat kinase 2. | Biochemical and biophysical research communications 20090116 |
| The junctional integrity of epithelial cells is modulated by Pseudomonas aeruginosa quorum sensing molecule through phosphorylation-dependent mechanisms. | Experimental cell research 20090115 |
| Complementary actions of BDNF and neurotrophin-3 on the firing patterns and synaptic composition of motoneurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090114 |
| Reversibility of apoptosis in cancer cells. | British journal of cancer 20090113 |
| Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases. | Journal of medicinal chemistry 20090108 |
| Gene therapy of neural cell injuries in vitro using the hypoxia-inducible GM-CSF expression plasmids and water-soluble lipopolymer (WSLP). | Journal of controlled release : official journal of the Controlled Release Society 20090105 |
| Alphaxalone, a neurosteroid anaesthetic, increases the activity of the glutamate transporter type 3 expressed in Xenopus oocytes. | European journal of pharmacology 20090105 |
| Matrix metalloproteinase-21 expression is associated with keratinocyte differentiation and upregulated by retinoic acid in HaCaT cells. | The Journal of investigative dermatology 20090101 |
| 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one inhibits neurite outgrowth and causes neurite retraction in PC12 cells independently of soluble guanylyl cyclase. | Journal of neuroscience research 20090101 |
| A system for analyzing the event timing profile of single cells by using a model of neurite maturation in PC12D cells. | Biosensors & bioelectronics 20090101 |
| Post-translational modification of cyclin A1 is associated with staurosporine and TNFalpha induced apoptosis in leukemic cells. | Molecular and cellular biochemistry 20090101 |
| Silencing of membrane-associated sialidase Neu3 diminishes apoptosis resistance and triggers megakaryocytic differentiation of chronic myeloid leukemic cells K562 through the increase of ganglioside GM3. | Cell death and differentiation 20090101 |
| Mitochondrial abnormalities in spinal and bulbar muscular atrophy. | Human molecular genetics 20090101 |
| The role of GSH efflux in staurosporine-induced apoptosis in colonic epithelial cells. | Biochemical pharmacology 20090101 |
| Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers. | Journal of immunological methods 20090101 |
| E-cadherin decreased human breast cancer cells sensitivity to staurosporine by up-regulating Bcl-2 expression. | Archives of biochemistry and biophysics 20090101 |
| Differential insult-dependent recruitment of the intrinsic mitochondrial pathway during neuronal programmed cell death. | Cellular and molecular life sciences : CMLS 20090101 |
| Regions of the amino terminus of the P2X receptor required for modification by phorbol ester and mGluR1alpha receptors. | Journal of neurochemistry 20090101 |
| Proteolysis of the tumour suppressor hDlg in response to osmotic stress is mediated by caspases and independent of phosphorylation. | The FEBS journal 20090101 |
| Pathology is alleviated by doxycycline in a laminin-alpha2-null model of congenital muscular dystrophy. | Annals of neurology 20090101 |
| Electrochemical detection of protein tyrosine kinase-catalysed phosphorylation using gold nanoparticles. | Biosensors & bioelectronics 20090101 |
| Chemical biology of natural indolocarbazole products: 30 years since the discovery of staurosporine. | The Journal of antibiotics 20090101 |
| Norrin attenuates protease-mediated death of transformed retinal ganglion cells. | Molecular vision 20090101 |
| Glycine receptor in rat hippocampal and spinal cord neurons as a molecular target for rapid actions of 17-beta-estradiol. | Molecular pain 20090101 |
| The critical role of ERK in death resistance and invasiveness of hypoxia-selected glioblastoma cells. | BMC cancer 20090101 |
| Genomic and non-genomic effect of cortisol on phagocytosis in freshwater teleost Channa punctatus: an in vitro study. | Steroids 20090101 |
| Influence of brain-derived neurotrophic factor on pathfinding of dentate granule cell axons, the hippocampal mossy fibers. | Molecular brain 20090101 |
| Activation of the heat shock response in a primary cellular model of motoneuron neurodegeneration-evidence for neuroprotective and neurotoxic effects. | Cellular & molecular biology letters 20090101 |
| Ca(2+) permeable AMPA receptor induced long-term potentiation requires PI3/MAP kinases but not Ca/CaM-dependent kinase II. | PloS one 20090101 |
| Identifying tumor cell growth inhibitors by combinatorial chemistry and zebrafish assays. | PloS one 20090101 |
| Spinocerebellar ataxia type 8 larger triplet expansion alters histone modification and induces RNA foci. | BMC molecular biology 20090101 |
| Centrosome-associated regulators of the G(2)/M checkpoint as targets for cancer therapy. | Molecular cancer 20090101 |
| Transmembrane voltage regulates binding of annexin V and lactadherin to cells with exposed phosphatidylserine. | BMC biochemistry 20090101 |
| Molecular mechanisms of paraptosis induction: implications for a non-genetically modified tumor vaccine. | PloS one 20090101 |
| Linoleic acid induces mouse embryonic stem cell proliferation via Ca2+/PKC, PI3K/Akt, and MAPKs. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20090101 |
| Connexins: a myriad of functions extending beyond assembly of gap junction channels. | Cell communication and signaling : CCS 20090101 |
| HIV gp120 induces, NF-kappaB dependent, HIV replication that requires procaspase 8. | PloS one 20090101 |
| Dysregulated apoptosis and NFkappaB expression in COPD subjects. | Respiratory research 20090101 |
| Rational mutagenesis to support structure-based drug design: MAPKAP kinase 2 as a case study. | BMC structural biology 20090101 |
| Effect of inhibitors of mitogen-activated protein kinase kinase on alpha(1B)-adrenoceptor phosphorylation. | Autonomic & autacoid pharmacology 20090101 |
| Practical and reliable FRET/FLIM pair of fluorescent proteins. | BMC biotechnology 20090101 |
| Bicaudal is a conserved substrate for Drosophila and mammalian caspases and is essential for cell survival. | PloS one 20090101 |
| Local ATP generation by brain-type creatine kinase (CK-B) facilitates cell motility. | PloS one 20090101 |
| The anti-apoptotic activity of BAG3 is restricted by caspases and the proteasome. | PloS one 20090101 |
| CHK1 inhibition as a strategy for targeting Fanconi Anemia (FA) DNA repair pathway deficient tumors. | Molecular cancer 20090101 |
| Chromatin conformation signatures of cellular differentiation. | Genome biology 20090101 |
| Phagocytosis of Staphylococcus aureus by macrophages exerts cytoprotective effects manifested by the upregulation of antiapoptotic factors. | PloS one 20090101 |
| NMDA receptor stimulation induces reversible fission of the neuronal endoplasmic reticulum. | PloS one 20090101 |
| Stilbene glycosides are natural product inhibitors of FGF-2-induced angiogenesis. | BMC cell biology 20090101 |
| Betulin is a potent anti-tumor agent that is enhanced by cholesterol. | PloS one 20090101 |
| Activation of p53-regulated pro-apoptotic signaling pathways in PrP-mediated myopathy. | BMC genomics 20090101 |
| Involvment of cytosolic and mitochondrial GSK-3beta in mitochondrial dysfunction and neuronal cell death of MPTP/MPP-treated neurons. | PloS one 20090101 |
| The necrotic signal induced by mycophenolic acid overcomes apoptosis-resistance in tumor cells. | PloS one 20090101 |
| BH3 peptides induce mitochondrial fission and cell death independent of BAX/BAK. | PloS one 20090101 |
| Complement C1q activates tumor suppressor WWOX to induce apoptosis in prostate cancer cells. | PloS one 20090101 |
| Transcriptional down-regulation and rRNA cleavage in Dictyostelium discoideum mitochondria during Legionella pneumophila infection. | PloS one 20090101 |
| Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1. | PloS one 20090101 |
| Effect of staurosporine on the mobility and invasiveness of lung adenocarcinoma A549 cells: an in vitro study. | BMC cancer 20090101 |
| Arylbenzazepines are potent modulators for the delayed rectifier K+ channel: a potential mechanism for their neuroprotective effects. | PloS one 20090101 |
| Priming of Salmonella enterica serovar typhi-specific CD8(+) T cells by suicide dendritic cell cross-presentation in humans. | PloS one 20090101 |
| A novel mechanism of hippocampal LTD involving muscarinic receptor-triggered interactions between AMPARs, GRIP and liprin-alpha. | Molecular brain 20090101 |
| Reduced axonal transport in Parkinson's disease cybrid neurites is restored by light therapy. | Molecular neurodegeneration 20090101 |
| Deoxycholate induces COX-2 expression via Erk1/2-, p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells. | BMC cancer 20090101 |
| CCHCR1 is up-regulated in skin cancer and associated with EGFR expression. | PloS one 20090101 |
| [Expression of connexin 43 in ovarian cancer and its relationship with chemoresistance]. | Zhonghua fu chan ke za zhi 20090101 |
| Phenotype-dependent apoptosis signalling in mesothelioma cells after selenite exposure. | Journal of experimental & clinical cancer research : CR 20090101 |
| Analysis of host- and strain-dependent cell death responses during infectious salmon anemia virus infection in vitro. | Virology journal 20090101 |
| Regulated release of BDNF by cortical oligodendrocytes is mediated through metabotropic glutamate receptors and the PLC pathway. | ASN neuro 20090101 |
| Role of ERK/MAPK in endothelin receptor signaling in human aortic smooth muscle cells. | BMC cell biology 20090101 |
| Heterogeneity in macrophage phagocytosis of Staphylococcus aureus strains: high-throughput scanning cytometry-based analysis. | PloS one 20090101 |
| Malaria ookinetes exhibit multiple markers for apoptosis-like programmed cell death in vitro. | Parasites & vectors 20090101 |
| Characterization of MCF mammary epithelial cells overexpressing the Arylhydrocarbon receptor (AhR). | BMC cancer 20090101 |
| Staurosporine augments EGF-mediated EMT in PMC42-LA cells through actin depolymerisation, focal contact size reduction and Snail1 induction - a model for cross-modulation. | BMC cancer 20090101 |
| Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein. | BMC cell biology 20090101 |
| Depletion of intrinsic expression of Interleukin-8 in prostate cancer cells causes cell cycle arrest, spontaneous apoptosis and increases the efficacy of chemotherapeutic drugs. | Molecular cancer 20090101 |
| cIAP-1 controls innate immunity to C. pneumoniae pulmonary infection. | PloS one 20090101 |
| Are small GTPases signal hubs in sugar-mediated induction of fructan biosynthesis? | PloS one 20090101 |
| A nanoconjugate Apaf-1 inhibitor protects mesothelial cells from cytokine-induced injury. | PloS one 20090101 |
| CK2 is the regulator of SIRT1 substrate-binding affinity, deacetylase activity and cellular response to DNA-damage. | PloS one 20090101 |
| Romidepsin inhibits Ras-dependent growth transformation of NIH 3T3 fibroblasts and RIE-1 epithelial cells independently of Ras signaling inhibition. | Journal of molecular signaling 20090101 |
| Involvement of VDAC, Bax and ceramides in the efflux of AIF from mitochondria during curcumin-induced apoptosis. | PloS one 20090101 |
| Imatinib induces apoptosis by inhibiting PDGF- but not insulin-induced PI 3-kinase/Akt survival signaling in RGC-5 retinal ganglion cells. | Molecular vision 20090101 |
| Cholinergic receptor pathways involved in apoptosis, cell proliferation and neuronal differentiation. | Cell communication and signaling : CCS 20090101 |
| Docetaxel-induced prostate cancer cell death involves concomitant activation of caspase and lysosomal pathways and is attenuated by LEDGF/p75. | Molecular cancer 20090101 |
| Glucocorticoid evoked upregulation of RCAN1-1 in human leukemic CEM cells susceptible to apoptosis. | Journal of molecular signaling 20090101 |
| VX-166: a novel potent small molecule caspase inhibitor as a potential therapy for sepsis. | Critical care (London, England) 20090101 |
| The mode of lymphoblastoid cell death in response to gas phase cigarette smoke is dose-dependent. | Respiratory research 20090101 |
| A secretory phospholipase A2-mediated neuroprotection and anti-apoptosis. | BMC neuroscience 20090101 |
| Iron labeling and pre-clinical MRI visualization of therapeutic human neural stem cells in a murine glioma model. | PloS one 20090101 |
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| Differential protection by wildtype vs. organelle-specific Bcl-2 suggests a combined requirement of both the ER and mitochondria in ceramide-mediated caspase-independent programmed cell death. | Radiation oncology (London, England) 20090101 |
| Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells. | PloS one 20090101 |
| Empirical Bayes analysis of quantitative proteomics experiments. | PloS one 20090101 |
| Caspase-dependent inhibition of mousepox replication by gzmB. | PloS one 20090101 |
| A novel function of ethylene. | Gene regulation and systems biology 20090101 |
| Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor. | PloS one 20090101 |
| Human cell chips: adapting DNA microarray spotting technology to cell-based imaging assays. | PloS one 20090101 |
| Protein kinase C promotes restoration of calcium homeostasis to platelet activating factor-stimulated human neutrophils by inhibition of phospholipase C. | Journal of inflammation (London, England) 20090101 |
| [Role of tyrosine kinase of Trk-receptors in realization of antioxidant effect of ganglioside GM1 in PC12 cells]. | Zhurnal evoliutsionnoi biokhimii i fiziologii 20090101 |
| A concerted kinase interplay identifies PPARgamma as a molecular target of ghrelin signaling in macrophages. | PloS one 20090101 |
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| A luciferase based viability assay for ATP detection in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427. | Parasites & vectors 20090101 |
| Dramatic co-activation of WWOX/WOX1 with CREB and NF-kappaB in delayed loss of small dorsal root ganglion neurons upon sciatic nerve transection in rats. | PloS one 20090101 |
| Anthrax lethal toxin induced lysosomal membrane permeabilization and cytosolic cathepsin release is Nlrp1b/Nalp1b-dependent. | PloS one 20090101 |
| Evidence for a lack of a direct transcriptional suppression of the iron regulatory peptide hepcidin by hypoxia-inducible factors. | PloS one 20090101 |
| Induction of granzyme B expression in T-cell receptor/CD28-stimulated human regulatory T cells is suppressed by inhibitors of the PI3K-mTOR pathway. | BMC immunology 20090101 |
| Critical involvement of Rho GTPase activity in the efficient transplantation of neural stem cells into the injured spinal cord. | Molecular brain 20090101 |
| Structural diversity of the active N-terminal kinase domain of p90 ribosomal S6 kinase 2. | PloS one 20090101 |
| Computational identification and experimental validation of PPRE motifs in NHE1 and MnSOD genes of human. | BMC genomics 20090101 |
| Glimepiride reduces the expression of PrPc, prevents PrPSc formation and protects against prion mediated neurotoxicity in cell lines. | PloS one 20090101 |
| Effects of triamcinolone acetonide on vessels of the posterior segment of the eye. | Molecular vision 20090101 |
| Identification of small molecule and genetic modulators of AON-induced dystrophin exon skipping by high-throughput screening. | PloS one 20090101 |
| ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology. | Journal of neuroinflammation 20090101 |
| Differential expression of apoptotic genes PDIA3 and MAP3K5 distinguishes between low- and high-risk prostate cancer. | Molecular cancer 20090101 |
| Wavelength-dependent backscattering measurements for quantitative real-time monitoring of apoptosis in living cells. | Journal of biomedical optics 20090101 |
| Study of the cytotoxicity and antioxidant capacity of N/OFQ(1-13)NH2 and its structural analogues. | Pharmacological reports : PR 20090101 |
| In vitro viability and cytotoxicity testing and same-well multi-parametric combinations for high throughput screening. | Current chemical genomics 20090101 |
| Small molecule protein interaction profiling with functional protein microarrays. | Methods in molecular biology (Clifton, N.J.) 20090101 |
| The spinocerebellar ataxia 12 gene product and protein phosphatase 2A regulatory subunit Bbeta2 antagonizes neuronal survival by promoting mitochondrial fission. | The Journal of biological chemistry 20081226 |
| Neuroprotection of microglia conditioned media from apoptotic death induced by staurosporine and glutamate in cultures of rat cerebellar granule cells. | Neuroscience letters 20081219 |
| In vitro protein kinase activity measurement by flow cytometry. | Analytical biochemistry 20081215 |
| Antileukemic effects of the novel, mutant FLT3 inhibitor NVP-AST487: effects on PKC412-sensitive and -resistant FLT3-expressing cells. | Blood 20081215 |
| Multiple kinases regulate mafA expression in the pancreatic beta cell line MIN6. | Archives of biochemistry and biophysics 20081215 |
| The importance of CH/pi hydrogen bonds in rational drug design: An ab initio fragment molecular orbital study to leukocyte-specific protein tyrosine (LCK) kinase. | Bioorganic & medicinal chemistry 20081215 |
| Peptide biosensors for the electrochemical measurement of protein kinase activity. | Analytical chemistry 20081215 |
| Insulin-like growth factor-1 inhibits STS-induced cell death and increases functional recovery of in vitro differentiated neurons. | Cell cycle (Georgetown, Tex.) 20081215 |
| Nerve growth factor acts with the beta2-adrenoceptor to induce spontaneous nociceptive behavior during temporomandibular joint inflammatory hyperalgesia. | Life sciences 20081205 |
| Bradykinin stimulates glutamate uptake via both B1R and B2R activation in a human retinal pigment epithelial cells. | Life sciences 20081205 |
| Chronic morphine application is protective against cell death in primary human neurons. | Neuroreport 20081203 |
| Antiproliferative activity of PEP005, a novel ingenol angelate that modulates PKC functions, alone and in combination with cytotoxic agents in human colon cancer cells. | British journal of cancer 20081202 |
| Characterization and intracellular localization of putative Chlamydia pneumoniae effector proteins. | Medical microbiology and immunology 20081201 |
| Apaf-1-deficient fog mouse cell apoptosis involves hypo-polarization of the mitochondrial inner membrane, ATP depletion and citrate accumulation. | Cell research 20081201 |
| Involvement of gD/HVEM interaction in NF-kB-dependent inhibition of apoptosis by HSV-1 gD. | Biochemical pharmacology 20081201 |
| Evidence for the possible involvement of the P2Y(6) receptor in Ca (2+) mobilization and insulin secretion in mouse pancreatic islets. | Purinergic signalling 20081201 |
| An increase in intracellular Ca2+ is required for the activation of mitochondrial calpain to release AIF during cell death. | Cell death and differentiation 20081201 |
| Presynaptic and postsynaptic NMDA receptors mediate distinct effects of brain-derived neurotrophic factor on synaptic transmission. | Journal of neurophysiology 20081201 |
| Identification of small molecule inhibitors of the mitotic kinase haspin by high-throughput screening using a homogeneous time-resolved fluorescence resonance energy transfer assay. | Journal of biomolecular screening 20081201 |
| Use of staurosporine, an actin-modifying agent, to enhance fibrochondrocyte matrix gene expression and synthesis. | Cell and tissue research 20081201 |
| Mitogen-activated protein kinase signaling enhances sodium iodide symporter function and efficacy of radioiodide therapy in nonthyroidal cancer cells. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20081201 |
| Mass-spectrometric characterization of phospholipids and their primary peroxidation products in rat cortical neurons during staurosporine-induced apoptosis. | Journal of neurochemistry 20081201 |
| The effect of alpha-synuclein knockdown on MPP+ toxicity in models of human neurons. | The European journal of neuroscience 20081201 |
| PKMzeta maintains spatial, instrumental, and classically conditioned long-term memories. | PLoS biology 20081201 |
| [The effect of recombinant human erythropoietin on the migration of bone marrow derived mesenchymal stem cells in vitro]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20081201 |
| Agmatine pretreatment protects retinal ganglion cells (RGC-5 cell line) from oxidative stress in vitro. | Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al 20081201 |
| Electrospray ionization mass spectra of piperazimycins A and B and gamma-butyrolactones from a marine-derived Streptomyces sp. | The Journal of antibiotics 20081201 |
| Regulation of tumor progression by extracellular galectin-3. | Cancer microenvironment : official journal of the International Cancer Microenvironment Society 20081201 |
| An integral approach to the etiopathogenesis of human neurodegenerative diseases (HNDDs) and cancer. Possible therapeutic consequences within the frame of the trophic factor withdrawal syndrome (TFWS). | Neuropsychiatric disease and treatment 20081201 |
| Deuterated polymer gels for measuring anisotropic NMR parameters with strongly reduced artefacts. | Chemical communications (Cambridge, England) 20081130 |
| PTP1B is a negative regulator of interleukin 4-induced STAT6 signaling. | Blood 20081115 |
| The motor complex of Plasmodium falciparum: phosphorylation by a calcium-dependent protein kinase. | The Journal of biological chemistry 20081107 |
| In vivo BDNF modulation of adult functional and morphological synaptic plasticity at hippocampal mossy fibers. | Neuroscience letters 20081107 |
| Lumican affects actin cytoskeletal organization in human melanoma A375 cells. | Life sciences 20081107 |
| The probiotic Lactobacillus GG may augment intestinal host defense by regulating apoptosis and promoting cytoprotective responses in the developing murine gut. | Pediatric research 20081101 |
| Volume-activated chloride channels in mice Leydig cells. | Pflugers Archiv : European journal of physiology 20081101 |
| On the role of major vault protein in the resistance of senescent human diploid fibroblasts to apoptosis. | Cell death and differentiation 20081101 |
| Characterization of the transduction pathway involved in c-fos and c-jun expression induced by Aggregatibacter actinomycetemcomitans lipopolysaccharides in human gingival fibroblasts. | International immunopharmacology 20081101 |
| Protein kinase C modulates synaptic vesicle acidification in a ribbon type nerve terminal in the retina. | Neurochemistry international 20081101 |
| Protein kinase C-delta mediates von Willebrand factor secretion from endothelial cells in response to vascular endothelial growth factor (VEGF) but not histamine. | Journal of thrombosis and haemostasis : JTH 20081101 |
| Comparative analyses of Arabidopsis complex glycan1 mutants and genetic interaction with staurosporin and temperature sensitive3a. | Plant physiology 20081101 |
| Sphingosine kinase 1 and 2 regulate the capacity of mesangial cells to resist apoptotic stimuli in an opposing manner. | Biological chemistry 20081101 |
| The plant alkaloid voacamine induces apoptosis-independent autophagic cell death on both sensitive and multidrug resistant human osteosarcoma cells. | Autophagy 20081101 |
| [The kinome and glucocorticoid-induced apoptosis]. | Ai zheng = Aizheng = Chinese journal of cancer 20081101 |
| Existing and emerging therapeutic options for the treatment of acute myeloid leukemia. | Clinical advances in hematology & oncology : H&O 20081101 |
| New agents for the treatment of AML recent study findings. | Clinical advances in hematology & oncology : H&O 20081101 |
| Future research directions for the treatment of AML. | Clinical advances in hematology & oncology : H&O 20081101 |
| KLF6 induces apoptosis in prostate cancer cells through up-regulation of ATF3. | The Journal of biological chemistry 20081031 |
| A eukaryotic-like Ser/Thr kinase signals bacteria to exit dormancy in response to peptidoglycan fragments. | Cell 20081031 |
| Emodin increases Ca(2+) influx through L-type Ca(2+) channel in guinea pig gallbladder smooth muscle. | European journal of pharmacology 20081024 |
| Deconstructing Survivin: comprehensive genetic analysis of Survivin function by conditional knockout in a vertebrate cell line. | The Journal of cell biology 20081020 |
| Proteinase-activated receptor 2 stimulates Na,K-ATPase and sodium reabsorption in native kidney epithelium. | The Journal of biological chemistry 20081017 |
| Role of NADPH oxidase in the apoptotic death of cultured cerebellar granule neurons. | Free radical biology & medicine 20081015 |
| Structure-activity relationship studies of imidazo[1,2-c]pyrimidine derivatives as potent and orally effective Syk family kinases inhibitors. | Bioorganic & medicinal chemistry 20081015 |
| Protective effects of Chinese propolis and its component, chrysin, against neuronal cell death via inhibition of mitochondrial apoptosis pathway in SH-SY5Y cells. | Journal of agricultural and food chemistry 20081008 |
| Adipogenic genes on induction and stabilization of commitment to adipose conversion. | Biochemical and biophysical research communications 20081003 |
| Heat-induced MMP-1 expression is mediated by TRPV1 through PKCalpha signaling in HaCaT cells. | Experimental dermatology 20081001 |
| Viability analysis and apoptosis induction of breast cancer cells in a microfluidic device: effect of cytostatic drugs. | Biomedical microdevices 20081001 |
| Stimulatory and suppressive signal transduction regulates vasoactive intestinal peptide receptor-1 (VPAC-1) in primary mouse CD4 T cells. | Brain, behavior, and immunity 20081001 |
| Inhibitory effect of 30-kDa phytoglycoprotein on expression of TNF-alpha and COX-2 via activation of PKCalpha and ERK 1/2 in LPS-stimulated RAW 264.7 cells. | Molecular and cellular biochemistry 20081001 |
| Rapid fluorescent assay for screening drugs on Leishmania amastigotes. | Journal of microbiological methods 20081001 |
| Tauroursodeoxycholic acid exerts anticholestatic effects by a cooperative cPKC alpha-/PKA-dependent mechanism in rat liver. | Gut 20081001 |
| Intracellular signaling dynamics during apoptosis execution in the presence or absence of X-linked-inhibitor-of-apoptosis-protein. | Biochimica et biophysica acta 20081001 |
| Multidrug resistance-associated protein 1 as a major mediator of basal and apoptotic glutathione release. | Biochimica et biophysica acta 20081001 |
| Autophagic death of adult hippocampal neural stem cells following insulin withdrawal. | Stem cells (Dayton, Ohio) 20081001 |
| Initiation of testicular tubulogenesis is controlled by neurotrophic tyrosine receptor kinases in a three-dimensional Sertoli cell aggregation assay. | Reproduction (Cambridge, England) 20081001 |
| BDNF-TrkB signaling interacts with the GABAergic system to inhibit rhythmic swallowing in the rat. | American journal of physiology. Regulatory, integrative and comparative physiology 20081001 |
| A potential role of connexin 43 in epidermal growth factor-induced proliferation of mouse embryonic stem cells: involvement of Ca2+/PKC, p44/42 and p38 MAPKs pathways. | Cell proliferation 20081001 |
| Voltage-dependent anion channels (VDAC) in the plasma membrane play a critical role in apoptosis in differentiated hippocampal neurons but not in neural stem cells. | Cell cycle (Georgetown, Tex.) 20081001 |
| Extracellular ATP-induced NO production and its dependence on membrane Ca2+ flux in Salvia miltiorrhiza hairy roots. | Journal of experimental botany 20081001 |
| PKC-Independent Stimulation of Cardiac Na/Ca Exchanger by Staurosporine. | The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20081001 |
| ATP modulates PTEN subcellular localization in multiple cancer cell lines. | Human molecular genetics 20080915 |
| Interruption of the Ras/MEK/ERK signaling cascade enhances Chk1 inhibitor-induced DNA damage in vitro and in vivo in human multiple myeloma cells. | Blood 20080915 |
| Cleavage-mediated activation of Chk1 during apoptosis. | The Journal of biological chemistry 20080912 |
| Structural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activation. | Cell 20080905 |
| Caspase-cleaved TAR DNA-binding protein-43 is a major pathological finding in Alzheimer's disease. | Brain research 20080904 |
| Molecular pathways involved in the synergistic interaction of the PKC beta inhibitor enzastaurin with the antifolate pemetrexed in non-small cell lung cancer cells. | British journal of cancer 20080902 |
| The cellular concentration of Bcl-2 determines its pro- or anti-apoptotic effect. | Cell calcium 20080901 |
| The upregulation of heat shock protein 70 expression in areca quid chewing-associated oral squamous cell carcinomas. | Oral oncology 20080901 |
| Concomitant transitory up-regulation of X-linked inhibitor of apoptosis protein (XIAP) and the heterogeneous nuclear ribonucleoprotein C1-C2 in surviving cells during neuronal apoptosis. | Neurochemical research 20080901 |
| PKC stimulated by glucagon decreases UT-A1 urea transporter expression in rat IMCD. | Pflugers Archiv : European journal of physiology 20080901 |
| Staurosporine rapidly commits 3T3-F442A cells to the formation of adipocytes by activation of GSK-3beta and mobilization of calcium. | Journal of cellular biochemistry 20080901 |
| Attenuation of hypoosmotic stress-induced ANP secretion via I(Cl,swell) in renal hypertensive rat atria. | Peptides 20080901 |
| Identification and functional analysis of SKA2 interaction with the glucocorticoid receptor. | The Journal of endocrinology 20080901 |
| HES-1 is involved in adaptation of adult human beta-cells to proliferation in vitro. | Diabetes 20080901 |
| The JNK inhibitor SP600129 enhances apoptosis of HCC cells induced by the tumor suppressor WWOX. | Journal of hepatology 20080901 |
| A structural insight into CK2 inhibition. | Molecular and cellular biochemistry 20080901 |
| The inhibitory effect of quercitrin gallate on iNOS expression induced by lipopolysaccharide in Balb/c mice. | Journal of veterinary science 20080901 |
| Oncostatin M induces bone loss and sensitizes rat osteosarcoma to the antitumor effect of Midostaurin in vivo. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080901 |
| Real-time imaging of mitochondria in transgenic zebrafish expressing mitochondrially targeted GFP. | BioTechniques 20080901 |
| Excitatory neurosteroids attenuate apoptotic and excitotoxic cell death in primary cortical neurons. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080901 |
| Prolonged morphine application modulates Bax and Hsp70 levels in primary rat neurons. | Neuroscience letters 20080829 |
| Redesigning kinase inhibitors to enhance specificity. | Journal of medicinal chemistry 20080828 |
| Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebM. | The Journal of biological chemistry 20080815 |
| Schwann cell mediated trophic effects by differentiated mesenchymal stem cells. | Experimental cell research 20080815 |
| Array-based fluorescence assay for serine/threonine kinases using specific chemical reaction. | Bioorganic & medicinal chemistry 20080815 |
| The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response. | The EMBO journal 20080806 |
| The FLT3 inhibitor PKC412 in combination with cytostatic drugs in vitro in acute myeloid leukemia. | Cancer chemotherapy and pharmacology 20080801 |
| Hypoxic induction of UCP3 in the growth plate: UCP3 suppresses chondrocyte autophagy. | Journal of cellular physiology 20080801 |
| Chemokine-like factor expression in the idiopathic inflammatory myopathies. | Acta neurologica Scandinavica 20080801 |
| Neurotrophins and their receptors stimulate melanoma cell proliferation and migration. | The Journal of investigative dermatology 20080801 |
| Role of inhibitor of apoptosis proteins and Smac/DIABLO in staurosporine-induced cerebellar granule neurons death. | Neurochemical research 20080801 |
| Homocysteine activates calcium-mediated cell signaling mechanisms targeting the cytoskeleton in rat hippocampus. | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20080801 |
| Vitamin D receptor-dependent 1 alpha,25(OH)2 vitamin D3-induced anti-apoptotic PI3K/AKT signaling in osteoblasts. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20080801 |
| The PKC and ERK/MAPK pathways regulate glucocorticoid action on TRH transcription. | Neurochemical research 20080801 |
| Insulin-like growth factor-I protects cells from ER stress-induced apoptosis via enhancement of the adaptive capacity of endoplasmic reticulum. | Cell death and differentiation 20080801 |
| Endosomal compartment contributes to the propagation of CD95/Fas-mediated signals in type II cells. | The Biochemical journal 20080801 |
| Activated caspase-6 and caspase-6-cleaved fragments of huntingtin specifically colocalize in the nucleus. | Human molecular genetics 20080801 |
| Rapid activation of Stat3 and ERK1/2 by nicotine modulates cell proliferation in human bladder cancer cells. | Toxicological sciences : an official journal of the Society of Toxicology 20080801 |
| Regulation by glucose of oscillatory electrical activity and 5-HT/insulin release from single mouse pancreatic islets in absence of functional K(ATP) channels. | Endocrine journal 20080801 |
| Permanent embryo arrest: molecular and cellular concepts. | Molecular human reproduction 20080801 |
| Role of brain-derived neurotrophic factor in hyperoxia-induced enhancement of contractility and impairment of relaxation in lung parenchyma. | American journal of physiology. Lung cellular and molecular physiology 20080801 |
| Nuclear Dbf2-related protein kinases (NDRs) in isolated cardiac myocytes and the myocardium: activation by cellular stresses and by phosphoprotein serine-/threonine-phosphatase inhibitors. | Cellular signalling 20080801 |
| BDNF induces late-phase LTP of C-fiber evoked field potentials in rat spinal dorsal horn. | Experimental neurology 20080801 |
| A novel Syk family kinase inhibitor: design, synthesis, and structure-activity relationship of 1,2,4-triazolo[4,3-c]pyrimidine and 1,2,4-triazolo[1,5-c]pyrimidine derivatives. | Bioorganic & medicinal chemistry 20080801 |
| Activated Rho/Rho kinase and modified calcium sensitivity in cryopreserved human saphenous veins. | Cryobiology 20080801 |
| CD95 ligation and intracellular membrane flow. | The Biochemical journal 20080801 |
| Pyrrolocarbazoles as checkpoint 1 kinase inhibitors. | Anti-cancer agents in medicinal chemistry 20080801 |
| NUPR1 interacts with p53, transcriptionally regulates p21 and rescues breast epithelial cells from doxorubicin-induced genotoxic stress. | Current cancer drug targets 20080801 |
| Vaccinia virus proteins A52 and B14 Share a Bcl-2-like fold but have evolved to inhibit NF-kappaB rather than apoptosis. | PLoS pathogens 20080801 |
| beta-Adrenoceptor blockers protect against staurosporine-induced apoptosis in SH-SY5Y neuroblastoma cells. | European journal of pharmacology 20080728 |
| Glutamate preconditioning prevents neuronal death induced by combined oxygen-glucose deprivation in cultured cortical neurons. | European journal of pharmacology 20080728 |
| Lysophosphatidic acid induced nuclear translocation of nuclear factor-kappaB in Panc-1 cells by mobilizing cytosolic free calcium. | World journal of gastroenterology 20080728 |
| Spheciosterol sulfates, PKCzeta inhibitors from a philippine sponge Spheciospongia sp. | Journal of natural products 20080725 |
| Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity. | Journal of medicinal chemistry 20080724 |
| Death receptors and caspases but not mitochondria are activated in the GDNF- or BDNF-deprived dopaminergic neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080723 |
| Ribosomal protein S6 is a selective mediator of TRAIL-apoptotic signaling. | Oncogene 20080717 |
| Endothelins stimulate the production of stromelysin-1 in cultured rat astrocytes. | Biochemical and biophysical research communications 20080711 |
| Expression and subcellular localization of thymosin beta15 following kainic acid treatment in rat brain. | Biochemical and biophysical research communications 20080711 |
| Design, synthesis, and biological evaluation of novel 3-aryl-4-(1H-indole-3yl)-1,5-dihydro-2H-pyrrole-2-ones as vascular endothelial growth factor receptor (VEGF-R) inhibitors. | Journal of medicinal chemistry 20080710 |
| Extracellular signal-regulated kinase phosphorylation due to menadione-induced arylation mediates growth inhibition of pancreas cancer cells. | Cancer chemotherapy and pharmacology 20080701 |
| Upregulation of hippocampal TrkB and synaptotagmin is involved in treadmill exercise-enhanced aversive memory in mice. | Neurobiology of learning and memory 20080701 |
| Zfra is an inhibitor of Bcl-2 expression and cytochrome c release from the mitochondria. | Cellular signalling 20080701 |
| Extracellular ATP activates the PLC/PKC/ERK signaling pathway through the P2Y2 purinergic receptor leading to the induction of early growth response 1 expression and the inhibition of viability in human endometrial stromal cells. | Cellular signalling 20080701 |
| Blockade of NGF and trk receptors inhibits increased peripheral mechanical sensitivity accompanying cystitis in rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20080701 |
| Brain-derived neurotrophic factor enhances the excitability of rat sensory neurons through activation of the p75 neurotrophin receptor and the sphingomyelin pathway. | The Journal of physiology 20080701 |
| Hypertonicity-induced cation channels rescue cells from staurosporine-elicited apoptosis. | Apoptosis : an international journal on programmed cell death 20080701 |
| Comparative study of ezrin phosphorylation among different tissues: more is good; too much is bad. | American journal of physiology. Cell physiology 20080701 |
| Irradiation leads to apoptosis of Kupffer cells by a Hsp27-dependant pathway followed by release of TNF-alpha. | Radiation and environmental biophysics 20080701 |
| Anti-inflammatory effects of dimemorfan on inflammatory cells and LPS-induced endotoxin shock in mice. | British journal of pharmacology 20080701 |
| Identification of a caspase-derived N-terminal tau fragment in cellular and animal Alzheimer's disease models. | Molecular and cellular neurosciences 20080701 |
| Development of a novel fluorescent probe for fluorescence correlation spectroscopic detection of kinase inhibitors. | Bioorganic & medicinal chemistry letters 20080701 |
| Inhibition of the activity of excitatory amino acid transporter 4 expressed in Xenopus oocytes after chronic exposure to ethanol. | Alcoholism, clinical and experimental research 20080701 |
| Protein kinase C function in muscle, liver, and beta-cells and its therapeutic implications for type 2 diabetes. | Diabetes 20080701 |
| Sites of action of hydrogen peroxide on ion transport across rat distal colon. | British journal of pharmacology 20080701 |
| Staurosporine aglycone bilaterally regulates ERK1/2 phosphorylation in rat pulmonary arterial smooth muscle cells. | Canadian journal of physiology and pharmacology 20080701 |
| Chk1 inhibition activates p53 through p38 MAPK in tetraploid cancer cells. | Cell cycle (Georgetown, Tex.) 20080701 |
| Hypoxia-induced resistance to anticancer drugs is associated with decreased senescence and requires hypoxia-inducible factor-1 activity. | Molecular cancer therapeutics 20080701 |
| IFNalpha and IFNlambda differ in their antiproliferative effects and duration of JAK/STAT signaling activity. | Cancer biology & therapy 20080701 |
| Evaluation of the Litron In Vitro MicroFlow Kit for the flow cytometric enumeration of micronuclei (MN) in mammalian cells. | Mutation research 20080630 |
| Cytosolic accumulation of gammaH2AX is associated with tropomyosin-related kinase A-induced cell death in U2OS cells. | Experimental & molecular medicine 20080630 |
| Protection against heat and staurosporine mediated apoptosis by the HSV-1 US11 protein. | Virology 20080620 |
| Calbindin-D28K prevents drug-induced dopaminergic neuronal death by inhibiting caspase and calpain activity. | Biochemical and biophysical research communications 20080620 |
| G2/M checkpoint stringency is a key parameter in the sensitivity of AML cells to genotoxic stress. | Oncogene 20080619 |
| TrkA kinase inhibitors from a library of modified and isosteric Staurosporine aglycone. | Bioorganic & medicinal chemistry letters 20080615 |
| Kaposi's sarcoma-associated herpesvirus confers a survival advantage to endothelial cells. | Cancer research 20080615 |
| TERT promotes cellular and organismal survival independently of telomerase activity. | Oncogene 20080612 |
| Dopamine D1 receptor-induced signaling through TrkB receptors in striatal neurons. | The Journal of biological chemistry 20080606 |
| IGF1 promotes resistance to apoptosis in melanoma cells through an increased expression of BCL2, BCL-X(L), and survivin. | The Journal of investigative dermatology 20080601 |
| Bcl-xL prevents staurosporine-induced hepatocyte apoptosis by restoring protein kinase B/mitogen-activated protein kinase activity and mitochondria integrity. | Journal of cellular physiology 20080601 |
| mRNA expression of Bcl-2, Bax, caspase-3 and -7 cannot be used as a marker for apoptosis in bovine blastocysts. | Animal reproduction science 20080601 |
| Tumour necrosis factor alpha upregulates platelet CD40L in patients with heart failure. | Cardiovascular research 20080601 |
| Resistance of mtDNA-depleted cells to apoptosis. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20080601 |
| Membrane environment rather than tissue factor expression determines thrombin formation triggered by monocytic cells undergoing apoptosis. | Journal of leukocyte biology 20080601 |
| Impact of Bacillus thuringiensis toxin Cry1Ab on rumen epithelial cells (REC) - a new in vitro model for safety assessment of recombinant food compounds. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080601 |
| LeCTR2, a CTR1-like protein kinase from tomato, plays a role in ethylene signalling, development and defence. | The Plant journal : for cell and molecular biology 20080601 |
| Purinergic inhibition of Na⁺,K⁺,Cl⁻ cotransport in C11-MDCK cells: Role of stress-activated protein kinases. | Purinergic signalling 20080601 |
| Tanshinone IIB, a primary active constituent from Salvia miltiorrhiza, exerts neuroprotective effect via inhibition of neuronal apoptosis in vitro. | Phytotherapy research : PTR 20080601 |
| Brain-derived neurotrophic factor-mediated retrograde signaling required for the induction of long-term potentiation at inhibitory synapses of visual cortical pyramidal neurons. | Neuroscience research 20080601 |
| Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility. | Nature chemical biology 20080601 |
| DNA damage-induced S phase arrest in human breast cancer depends on Chk1, but G2 arrest can occur independently of Chk1, Chk2 or MAPKAPK2. | Cell cycle (Georgetown, Tex.) 20080601 |
| Cytotoxic staurosporines from the marine ascidian Cystodytes solitus. | Journal of natural products 20080601 |
| Antagonistic effect of juvenile hormone on hemocyte-spreading behavior of Spodoptera exigua in response to an insect cytokine and its putative membrane action. | Journal of insect physiology 20080601 |
| Bacillus anthracis spores and lethal toxin induce IL-1beta via functionally distinct signaling pathways. | European journal of immunology 20080601 |
| Specific proteolysis of the A-kinase-anchoring protein 149 at the Asp582 residue by caspases during apoptosis. | Oncology reports 20080601 |
| Hormonal regulation of regucalcin mRNA expression in osteoblastic MC3T3-E1 cells. | International journal of molecular medicine 20080601 |
| Dose- and time-dependent pharmacokinetics of midostaurin in patients with diabetes mellitus. | Journal of clinical pharmacology 20080601 |
| Induction of amyloid beta accumulation by ER calcium disruption and resultant upregulation of angiogenic factors in ARPE19 cells. | Investigative ophthalmology & visual science 20080601 |
| Clearing the brain's cobwebs: the role of autophagy in neuroprotection. | Current neuropharmacology 20080601 |
| Water and ion channels: crucial in the initiation and progression of apoptosis in central nervous system? | Current neuropharmacology 20080601 |
| Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane. | The Journal of biological chemistry 20080530 |
| ADAM10 regulates endothelial permeability and T-Cell transmigration by proteolysis of vascular endothelial cadherin. | Circulation research 20080523 |
| Curcumin protects against glutamate excitotoxicity in rat cerebral cortical neurons by increasing brain-derived neurotrophic factor level and activating TrkB. | Brain research 20080519 |
| The FLT3 inhibitor PKC412 exerts differential cell cycle effects on leukemic cells depending on the presence of FLT3 mutations. | Oncogene 20080515 |
| Phosphorylation regulates transcriptional activity of PAX3/FKHR and reveals novel therapeutic possibilities. | Cancer research 20080515 |
| Hexokinase-I protection against apoptotic cell death is mediated via interaction with the voltage-dependent anion channel-1: mapping the site of binding. | The Journal of biological chemistry 20080509 |
| A role for the cleaved cytoplasmic domain of E-cadherin in the nucleus. | The Journal of biological chemistry 20080509 |
| Degradation of caspase-activated DNase by the ubiquitin-proteasome system. | Biochimica et biophysica acta 20080501 |
| Prohibitin silencing reverses stabilization of mitochondrial integrity and chemoresistance in ovarian cancer cells by increasing their sensitivity to apoptosis. | International journal of cancer 20080501 |
| Effects of neurosteroids on hydrogen peroxide- and staurosporine-induced damage of human neuroblastoma SH-SY5Y cells. | Journal of neuroscience research 20080501 |
| Proapoptotic BH3-only protein Bid is essential for death receptor-induced apoptosis of pancreatic beta-cells. | Diabetes 20080501 |
| Endocytic downregulation of ErbB receptors: mechanisms and relevance in cancer. | Histochemistry and cell biology 20080501 |
| Enhancement of long-term potentiation by brain-derived neurotrophic factor requires adenosine A2A receptor activation by endogenous adenosine. | Neuropharmacology 20080501 |
| Inhibition of the rapid component of the delayed rectifier potassium current in ventricular myocytes by angiotensin II via the AT1 receptor. | British journal of pharmacology 20080501 |
| Nuclear localization of regucalcin is enhanced in culture with protein kinase C activation in cloned normal rat kidney proximal tubular epithelial NRK52E cells. | International journal of molecular medicine 20080501 |
| Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5. | Cancer research 20080501 |
| The uptake of apoptotic cells drives Coxiella burnetii replication and macrophage polarization: a model for Q fever endocarditis. | PLoS pathogens 20080501 |
| Viral control of mitochondrial apoptosis. | PLoS pathogens 20080501 |
| Protein tyrosine kinase inhibitors modify kainic acid-induced epileptiform activity and mossy fiber sprouting but do not protect against limbic cell death. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20080501 |
| Late onset sporadic Parkinson's disease caused by PINK1 mutations: clinical and functional study. | Movement disorders : official journal of the Movement Disorder Society 20080430 |
| [Protein kinase C regulates unloading contraction of cardiomyocytes in hypertrophic heart of spontaneously hypertensive rat]. | Sheng li xue bao : [Acta physiologica Sinica] 20080425 |
| Potential role of NADPH-oxidase in early steps of lead-induced oxidative burst in Vicia faba roots. | Journal of plant physiology 20080418 |
| Wild-type PABPN1 is anti-apoptotic and reduces toxicity of the oculopharyngeal muscular dystrophy mutation. | Human molecular genetics 20080415 |
| Profound inhibition of antigen-specific T-cell effector functions by dasatinib. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080415 |
| Protein kinase C inhibitors alter neurotensin receptor binding and function in prostate cancer PC3 cells. | Regulatory peptides 20080410 |
| Agonist-specific down regulation of mu-opioid receptors: Different cellular pathways are activated by different opioid agonists. | Life sciences 20080409 |
| A causal role for brain-derived neurotrophic factor in the homeostatic regulation of sleep. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080409 |
| The cardio-protecting agent and topoisomerase II catalytic inhibitor sobuzoxane enhances doxorubicin-DNA adduct mediated cytotoxicity. | Cancer chemotherapy and pharmacology 20080401 |
| Serine protease inhibitors N-alpha-tosyl-L-lysinyl-chloromethylketone (TLCK) and N-tosyl-L-phenylalaninyl-chloromethylketone (TPCK) are potent inhibitors of activated caspase proteases. | Journal of cellular biochemistry 20080401 |
| Fatty acids differentially influence phosphatidylinositol 3-kinase signal transduction in endothelial cells: impact on adhesion and apoptosis. | Atherosclerosis 20080401 |
| Acrolein induces heme oxygenase-1 through PKC-delta and PI3K in human bronchial epithelial cells. | American journal of respiratory cell and molecular biology 20080401 |
| Surface plasmon resonance imaging measurements of caspase reactions on peptide microarrays. | Analytical biochemistry 20080401 |
| Thiopental protects human T lymphocytes from apoptosis in vitro via the expression of heat shock protein 70. | The Journal of pharmacology and experimental therapeutics 20080401 |
| B7-H1 is a ubiquitous antiapoptotic receptor on cancer cells. | Blood 20080401 |
| Plasmodium falciparum: erythrocytic stages die by autophagic-like cell death under drug pressure. | Experimental parasitology 20080401 |
| Two independent forms of endocytosis maintain embryonic cell surface homeostasis during early development. | Developmental biology 20080401 |
| Bisindolylmaleimide IX facilitates extrinsic and initiates intrinsic apoptosis in TNF-alpha-resistant human colon adenocarcinoma COLO 205 cells. | Apoptosis : an international journal on programmed cell death 20080401 |
| Inhibition of PHF-like tau hyperphosphorylation in SH-SY5Y cells and rat brain slices by K252a. | Journal of Alzheimer's disease : JAD 20080401 |
| Asexual blood stages of Plasmodium falciparum exhibit signs of secondary necrosis, but not classical apoptosis after exposure to febrile temperature (40 C). | The Journal of parasitology 20080401 |
| [Protection and its mechanism of catechin morphon on hypoxia-reoxygenation [corrected] induced injury in myocardial cells]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080401 |
| [Effect of staurosporine induced apoptosis of MCF7/GFP-Bax stable cell line on Bax translocation from cytosol into mitochondria]. | Yao xue xue bao = Acta pharmaceutica Sinica 20080401 |
| Simultaneous induction of apoptotic, autophagic, and necrosis-like cell death by monoclonal antibodies recognizing chicken transferrin receptor. | Biochemical and biophysical research communications 20080321 |
| Methylprednisolone protects oligodendrocytes but not neurons after spinal cord injury. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080319 |
| Reduced potassium-chloride co-transporter expression in spinal cord dorsal horn neurons contributes to inflammatory pain hypersensitivity in rats. | Neuroscience 20080318 |
| Phosphorylation of beta-amyloid precursor protein (APP) cytoplasmic tail facilitates amyloidogenic processing during apoptosis. | Brain research 20080310 |
| Controlled release of a protein kinase inhibitor UCN-01 from liposomes influenced by the particle size. | International journal of pharmaceutics 20080303 |
| Phase I and pharmacokinetic study of UCN-01 in combination with irinotecan in patients with solid tumors. | Cancer chemotherapy and pharmacology 20080301 |
| A novel N-alkylated prodigiosin analogue induced death in tumour cell through apoptosis or necrosis depending upon the cell type. | Cancer chemotherapy and pharmacology 20080301 |
| High glucose induced translocation of Aquaporin8 to chicken hepatocyte plasma membrane: involvement of cAMP, PI3K/Akt, PKC, MAPKs, and microtubule. | Journal of cellular biochemistry 20080301 |
| Shb gene knockdown increases the susceptibility of SVR endothelial tumor cells to apoptotic stimuli in vitro and in vivo. | The Journal of investigative dermatology 20080301 |
| Apoptotic myocytes generate monocyte chemoattractant protein-1 and mediate macrophage recruitment. | Journal of applied physiology (Bethesda, Md. : 1985) 20080301 |
| Albumin-stimulated DNA synthesis is mediated by Ca2+/PKC as well as EGF receptor-dependent p44/42 MAPK and NF-kappaB signal pathways in renal proximal tubule cells. | American journal of physiology. Renal physiology 20080301 |
| Pim2 inhibitors from the Papua New Guinean plant Cupaniopsis macropetala. | Journal of natural products 20080301 |
| Identification of protein kinase D as a novel contraction-activated kinase linked to GLUT4-mediated glucose uptake, independent of AMPK. | Cellular signalling 20080301 |
| What makes a dead cell attractive? | Journal of applied physiology (Bethesda, Md. : 1985) 20080301 |
| BLOC1S2 interacts with the HIPPI protein and sensitizes NCH89 glioblastoma cells to apoptosis. | Apoptosis : an international journal on programmed cell death 20080301 |
| tPA protects renal interstitial fibroblasts and myofibroblasts from apoptosis. | Journal of the American Society of Nephrology : JASN 20080301 |
| Phytoglycoprotein inhibits interleukin-1beta and interleukin-6 via p38 mitogen-activated protein kinase in lipopolysaccharide-stimulated RAW 264.7 cells. | Naunyn-Schmiedeberg's archives of pharmacology 20080301 |
| Mechanisms regulating plasminogen activators in transformed retinal ganglion cells. | Experimental eye research 20080301 |
| K252a is highly effective in suppressing the growth of human endometrial cancer cells, but has little effect on normal human endometrial epithelial cells. | Oncology reports 20080301 |
| Leukemia inhibitory factor induces an antiapoptotic response in oligodendrocytes through Akt-phosphorylation and up-regulation of 14-3-3. | Proteomics 20080301 |
| Can FLT3 inhibitors overcome resistance in AML? | Best practice & research. Clinical haematology 20080301 |
| Transient exposure of carcinoma cells to RAS/MEK inhibitors and UCN-01 causes cell death in vitro and in vivo. | Molecular cancer therapeutics 20080301 |
| Effects of in vitro brevetoxin exposure on apoptosis and cellular metabolism in a leukemic T cell line (Jurkat). | Marine drugs 20080301 |
| Pharmacodynamics of memantine: an update. | Current neuropharmacology 20080301 |
| Activation of the mitochondrial death pathway is commonly mediated by a preferential engagement of Bak. | Oncogene 20080227 |
| Bfl-1/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist. | Oncogene 20080227 |
| Interlaboratory evaluation of a flow cytometric, high content in vitro micronucleus assay. | Mutation research 20080227 |
| Ebselen, a redox regulator containing a selenium atom, induces neurofilament M expression in cultured rat pheochromocytoma PC12 cells via activation of mitogen-activated protein kinase. | Journal of neuroscience research 20080215 |
| Staurosporine-based binding assay for testing the affinity of compounds to protein kinases. | Analytical biochemistry 20080215 |
| Cytoskeleton-interacting LIM-domain protein CRP1 suppresses cell proliferation and protects from stress-induced cell death. | Experimental cell research 20080215 |
| Nuclear localized protein-1 (Nulp1) increases cell death of human osteosarcoma cells and binds the X-linked inhibitor of apoptosis protein. | Biochemical and biophysical research communications 20080208 |
| Crosstalk between angiotensin II and platelet derived growth factor-BB mediated signal pathways in cardiomyocytes. | Chinese medical journal 20080205 |
| The most widespread desmosomal cadherin, desmoglein 2, is a novel target of caspase 3-mediated apoptotic machinery. | Journal of cellular biochemistry 20080201 |
| Mapping the ruthenium red-binding site of the voltage-dependent anion channel-1. | Cell calcium 20080201 |
| Pharmacodynamic study of FS-0311: a novel highly potent, selective acetylcholinesterase inhibitor. | Cellular and molecular neurobiology 20080201 |
| Early and late activation of the voltage-gated proton channel during lactic acidosis through pH-dependent and -independent mechanisms. | Pflugers Archiv : European journal of physiology 20080201 |
| Galectin 15 (LGALS15) functions in trophectoderm migration and attachment. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080201 |
| Lovastatin sensitized human glioblastoma cells to TRAIL-induced apoptosis. | Journal of neuro-oncology 20080201 |
| Regulation of CREB-mediated gene expression by salt inducible kinase. | The Journal of steroid biochemistry and molecular biology 20080201 |
| Identification of the prosurvival activity of nerve growth factor on cardiac myocytes. | Cell death and differentiation 20080201 |
| Lentivirus mediated HO-1 gene transfer enhances myogenic precursor cell survival after autologous transplantation in pig. | Molecular therapy : the journal of the American Society of Gene Therapy 20080201 |
| Macrophage apolipoprotein-E knockdown modulates caspase-3 activation without altering sensitivity to apoptosis. | Biochimica et biophysica acta 20080201 |
| Protein phosphatase 1H, overexpressed in colon adenocarcinoma, is associated with CSE1L. | Cancer biology & therapy 20080201 |
| Voltage-dependent potassium channels are involved in staurosporine-induced apoptosis of rat mesenchymal stem cells. | Cell biology international 20080201 |
| Hypothesis: human serum-borne albumin bound lipids promote cellular survival after apoptosis induction by a variety of stimuli. | Apoptosis : an international journal on programmed cell death 20080201 |
| Prostaglandin-induced VASP phosphorylation controls alpha II-spectrin breakdown in apoptotic cells. | International immunopharmacology 20080201 |
| Neurogenesis and cell cycle-reactivated neuronal death during pathogenic tau aggregation. | Genes, brain, and behavior 20080201 |
| Cytoplasmic condensation is both necessary and sufficient to induce apoptotic cell death. | Journal of cell science 20080201 |
| Histone deimination as a response to inflammatory stimuli in neutrophils. | Journal of immunology (Baltimore, Md. : 1950) 20080201 |
| Ethanol increases the activity of rat excitatory amino acid transporter type 4 expressed in Xenopus oocytes: role of protein kinase C and phosphatidylinositol 3-kinase. | Alcoholism, clinical and experimental research 20080201 |
| Brucella control of dendritic cell maturation is dependent on the TIR-containing protein Btp1. | PLoS pathogens 20080201 |
| Defective p53 signaling in p53 wild-type tumors attenuates p21waf1 induction and cyclin B repression rendering them sensitive to Chk1 inhibitors that abrogate DNA damage-induced S and G2 arrest. | Molecular cancer therapeutics 20080201 |
| [Blocking TrkB-BDNF signal pathway decreases the livability of neuroblastoma cells]. | Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20080201 |
| Lysophosphatidylcholine Increases Ca Current via Activation of Protein Kinase C in Rabbit Portal Vein Smooth Muscle Cells. | The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20080201 |
| Trk: a neuromodulator of age-specific behavioral and neurochemical responses to cocaine in mice. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080130 |
| Arabidopsis HY5 protein functions as a DNA-binding tag for purification and functional immobilization of proteins on agarose/DNA microplate. | FEBS letters 20080123 |
| Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation. | Molecular cell 20080118 |
| Increased inducible nitric oxide synthase in lung carcinoma of smokers. | Cancer 20080115 |
| Structure of the human protein kinase MPSK1 reveals an atypical activation loop architecture. | Structure (London, England : 1993) 20080108 |
| In vitro and in vivo neuroprotective effect and mechanisms of glabridin, a major active isoflavan from Glycyrrhiza glabra (licorice). | Life sciences 20080102 |
| Increased expression and altered subunit composition of proteasomes induced by continuous proteasome inhibition establish apoptosis resistance and hyperproliferation of Burkitt lymphoma cells. | Journal of cellular biochemistry 20080101 |
| Hypoxia induces epidermal keratinocyte matrix metalloproteinase-9 secretion via the protein kinase C pathway. | Journal of cellular physiology 20080101 |
| Autocrine NGFbeta/TRKA signalling is an important survival factor for Hodgkin lymphoma derived cell lines. | Leukemia research 20080101 |
| The C-terminal transmembrane domain of Bcl-xL mediates changes in mitochondrial morphology. | Biophysical journal 20080101 |
| Caspase-3-truncated type 1 inositol 1,4,5-trisphosphate receptor enhances intracellular Ca2+ leak and disturbs Ca2+ signalling. | Biology of the cell 20080101 |
| Novel vectors expressing anti-apoptotic protein Bcl-2 to study cell death in Semliki Forest virus-infected cells. | Virus research 20080101 |
| Inhibition of the NF-kappaB survival pathway via caspase-dependent cleavage of the IKK complex scaffold protein and NF-kappaB essential modulator NEMO. | Cell death and differentiation 20080101 |
| Early-stage apoptosis is associated with DNA-damage-independent ATM phosphorylation and chromatin decondensation in NIH3T3 fibroblasts. | Cell biology international 20080101 |
| Calcium influxes and mitogen-activated protein kinase kinase activation mediate ethylene inducing ipomoelin gene expression in sweet potato. | Plant, cell & environment 20080101 |
| Activation of mu-opioid receptor selectively potentiates NMDA-induced outward currents in rat locus coeruleus neurons. | Neuroscience research 20080101 |
| Calcitonin promotes outgrowth of trophoblast cells on endometrial epithelial cells: involvement of calcium mobilization and protein kinase C activation. | Placenta 20080101 |
| PACAP-38 induces neuronal differentiation of human SH-SY5Y neuroblastoma cells via cAMP-mediated activation of ERK and p38 MAP kinases. | Journal of neurochemistry 20080101 |
| The attenuating effect of memantine on staurosporine-, salsolinol- and doxorubicin-induced apoptosis in human neuroblastoma SH-SY5Y cells. | Neurochemistry international 20080101 |
| Morphological and cytochemical determination of cell death by apoptosis. | Histochemistry and cell biology 20080101 |
| Screening for compounds that induce apoptosis of cancer cells grown as multicellular spheroids. | Journal of biomolecular screening 20080101 |
| Acute effectors of GLUT1 glucose transporter subcellular targeting in CIT3 mouse mammary epithelial cells. | Pediatric research 20080101 |
| delta-Opioid receptor stimulation enhances the growth of neonatal rat ventricular myocytes via the extracellular signal-regulated kinase pathway. | Clinical and experimental pharmacology & physiology 20080101 |
| Micro-electrode flux estimation confirms that the Solanum pimpinellifolium cu3 mutant still responds to systemin. | Plant physiology 20080101 |
| Apoptosis-associated antigens recognized by autoantibodies in patients with the autoimmune liver disease primary biliary cirrhosis. | Apoptosis : an international journal on programmed cell death 20080101 |
| Ex vivo rapamycin generates apoptosis-resistant donor Th2 cells that persist in vivo and prevent hemopoietic stem cell graft rejection. | Journal of immunology (Baltimore, Md. : 1950) 20080101 |
| Molecular events involved in the increased expression of matrix metalloproteinase-9 by T lymphocytes of mammary tumor-bearing mice. | International journal of molecular medicine 20080101 |
| Differential production of superoxide by neuronal mitochondria. | BMC neuroscience 20080101 |
| A quantitative analysis of kinase inhibitor selectivity. | Nature biotechnology 20080101 |
| Targeting mitochondria. | Accounts of chemical research 20080101 |
| Derlin-1 is overexpressed in human breast carcinoma and protects cancer cells from endoplasmic reticulum stress-induced apoptosis. | Breast cancer research : BCR 20080101 |
| Biphasic onset of splenic apoptosis following hemorrhagic shock: critical implications for Bax, Bcl-2, and Mcl-1 proteins. | Critical care (London, England) 20080101 |
| A quantitative method to assess extrasynaptic NMDA receptor function in the protective effect of synaptic activity against neurotoxicity. | BMC neuroscience 20080101 |
| Inhibition of apoptosis in neuronal cells infected with Chlamydophila (Chlamydia) pneumoniae. | BMC neuroscience 20080101 |
| Cheiradone: a vascular endothelial cell growth factor receptor antagonist. | BMC cell biology 20080101 |
| [Gastrointestinal stromal tumors: molecular aspects and therapeutic implications]. | Bulletin du cancer 20080101 |
| Differential screening of phage-ab libraries by oligonucleotide microarray technology. | PloS one 20080101 |
| Apoptosis resistance in HIV-1 persistently-infected cells is independent of active viral replication and involves modulation of the apoptotic mitochondrial pathway. | Retrovirology 20080101 |
| Chlamydophila pneumoniae derived from inclusions late in the infectious cycle induce aponecrosis in human aortic endothelial cells. | BMC microbiology 20080101 |
| Protein kinase substrate identification on functional protein arrays. | BMC biotechnology 20080101 |
| Recombinant allergens promote expression of aminopeptidase-n (CD13) on basophils in allergic patients. | International journal of immunopathology and pharmacology 20080101 |
| A dual-color fluorescence-based platform to identify selective inhibitors of Akt signaling. | PloS one 20080101 |
| Granule formation in NGF-cultured mast cells is associated with expressions of pyruvate kinase type M2 and annexin I proteins. | International archives of allergy and immunology 20080101 |
| Huperzine A provides neuroprotection against several cell death inducers using in vitro model systems of motor neuron cell death. | Neurotoxicity research 20080101 |
| Cell death by SecTRAPs: thioredoxin reductase as a prooxidant killer of cells. | PloS one 20080101 |
| Apoptosis induction in Jurkat cells and sCD95 levels in women's sera are related with the risk of developing cervical cancer. | BMC cancer 20080101 |
| Cloning and characterization of a novel LpWRKY1 transcription factor in tomato. | Plant physiology and biochemistry : PPB 20080101 |
| Analyses of in vivo interaction and mobility of two spliceosomal proteins using FRAP and BiFC. | PloS one 20080101 |
| Neurotensin protects pancreatic beta cells from apoptosis. | The international journal of biochemistry & cell biology 20080101 |
| Effect of low molecular weight fucoidan and low molecular weight heparin in a rabbit model of arterial thrombosis. | Journal of vascular research 20080101 |
| Deoxysugars in bioactive natural products: development of novel derivatives by altering the sugar pattern. | Current topics in medicinal chemistry 20080101 |
| Inhibition of PKCalpha activation in human bone and soft tissue sarcoma cells by the selective PKC inhibitor PKC412. | Anticancer research 20080101 |
| Functional implications of plasma membrane condensation for T cell activation. | PloS one 20080101 |
| A simple and robust method for connecting small-molecule drugs using gene-expression signatures. | BMC bioinformatics 20080101 |
| Inhibition of casein kinase 1-epsilon induces cancer-cell-selective, PERIOD2-dependent growth arrest. | Genome biology 20080101 |
| Nitric oxide, a survival factor for lens epithelial cells. | Molecular vision 20080101 |
| Methods for simultaneous measurement of apoptosis and cell surface phenotype of epithelial cells in effusions by flow cytometry. | Nature protocols 20080101 |
| Free Brick1 is a trimeric precursor in the assembly of a functional wave complex. | PloS one 20080101 |
| PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons. | PloS one 20080101 |
| Porcine reproductive and respiratory syndrome virus modulates apoptosis during replication in alveolar macrophages. | Archives of virology 20080101 |
| Real-time monitoring of apoptosis by caspase-3-like protease induced FRET reduction triggered by amyloid aggregation. | Experimental diabetes research 20080101 |
| Prolonged classical NF-kappaB activation prevents autophagy upon E. coli stimulation in vitro: a potential resolving mechanism of inflammation. | Mediators of inflammation 20080101 |
| The WSB1 gene is involved in pancreatic cancer progression. | PloS one 20080101 |
| Combined effects of 5-fluorouracil, folinic acid and oxaliplatin on the expression of carcinoembryonic antigen in human colon cancer cells: pharmacological basis to develop an active antitumor immunochemotherapy. | Journal of experimental & clinical cancer research : CR 20080101 |
| Phosphorylation at Ser473 regulates heterochromatin protein 1 binding and corepressor function of TIF1beta/KAP1. | BMC molecular biology 20080101 |
| BRCA1 185delAG truncation protein, BRAt, amplifies caspase-mediated apoptosis in ovarian cells. | In vitro cellular & developmental biology. Animal 20080101 |
| Natriuretic peptides modify Pseudomonas fluorescens cytotoxicity by regulating cyclic nucleotides and modifying LPS structure. | BMC microbiology 20080101 |
| Systematic genetic array analysis links the Saccharomyces cerevisiae SAGA/SLIK and NuA4 component Tra1 to multiple cellular processes. | BMC genetics 20080101 |
| Epidermal growth factor protects fibroblasts from apoptosis via PI3 kinase and Rac signaling pathways. | Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20080101 |
| New steroidal aromatase inhibitors: suppression of estrogen-dependent breast cancer cell proliferation and induction of cell death. | BMC cell biology 20080101 |
| Bid participates in genotoxic drug-induced apoptosis of HeLa cells and is essential for death receptor ligands' apoptotic and synergistic effects. | PloS one 20080101 |
| Downregulation of protein disulfide isomerase in sepsis and its role in tumor necrosis factor-alpha release. | Critical care (London, England) 20080101 |
| A RasGAP SH3 peptide aptamer inhibits RasGAP-Aurora interaction and induces caspase-independent tumor cell death. | PloS one 20080101 |
| C4b-binding protein is present in affected areas of myocardial infarction during the acute inflammatory phase and covers a larger area than C3. | PloS one 20080101 |
| Signaling pathways required for macrophage scavenger receptor-mediated phagocytosis: analysis by scanning cytometry. | Respiratory research 20080101 |
| Critical role for BIM in T cell receptor restimulation-induced death. | Biology direct 20080101 |
| [Protein kinases C: a new cytoplasmic target]. | Bulletin du cancer 20080101 |
| Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a 'regulated' transcriptional role. | Molecular neurodegeneration 20080101 |
| DIDS attenuates staurosporine-induced cardiomyocyte apoptosis by PI3K/Akt signaling pathway: activation of eNOS/NO and inhibition of Bax translocation. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101 |
| Pump and channel K (Rb+) fluxes in apoptosis of human lymphoid cell line U937. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101 |
| Mcl-1 is a key regulator of apoptosis resistance in Chlamydia trachomatis-infected cells. | PloS one 20080101 |
| Subcellular forms and biochemical events triggered in human cells by HCV polyprotein expression from a viral vector. | Virology journal 20080101 |
| TOR complex 2 is needed for cell cycle progression and anchorage-independent growth of MCF7 and PC3 tumor cells. | BMC cancer 20080101 |
| Degradation of plectin with modulation of cytokeratin 18 in human liver cells during staurosporine-induced apoptosis. | In vivo (Athens, Greece) 20080101 |
| Assessment of neuroprotection in the retina with DARC. | Progress in brain research 20080101 |
| Effect of cytosolic pH on epithelial Na+ channel in normal and cystic fibrosis sweat ducts. | The Journal of membrane biology 20080101 |
| Extrasynaptic and postsynaptic receptors in glycinergic and GABAergic neurotransmission: a division of labor? | Frontiers in molecular neuroscience 20080101 |
| Identification and classification of genes regulated by phosphatidylinositol 3-kinase- and TRKB-mediated signalling pathways during neuronal differentiation in two subtypes of the human neuroblastoma cell line SH-SY5Y. | BMC research notes 20080101 |
| Raft-dependent endocytosis of autocrine motility factor/phosphoglucose isomerase: a potential drug delivery route for tumor cells. | PloS one 20080101 |
| Astrocytes play a key role in activation of microglia by persistent Borna disease virus infection. | Journal of neuroinflammation 20080101 |
| Spermatogonial stem cell sensitivity to capsaicin: an in vitro study. | Reproductive biology and endocrinology : RB&E 20080101 |
| A mechanism-based population pharmacokinetic model for characterizing time-dependent pharmacokinetics of midostaurin and its metabolites in human subjects. | Clinical pharmacokinetics 20080101 |
| Cell cycle arrest and apoptosis responses of human breast epithelial cells to the synthetic organosulfur compound p-methoxyphenyl p-toluenesulfonate. | Anticancer research 20080101 |
| Neurosteroids enhance the viability of staurosporine and doxorubicin treated differentiated human neuroblastoma SH-SY5Y cells. | Pharmacological reports : PR 20080101 |
| Role of cAMP in the promotion of colorectal cancer cell growth by prostaglandin E2. | BMC cancer 20080101 |
| Chronic, low-dose rotenone reproduces Lewy neurites found in early stages of Parkinson's disease, reduces mitochondrial movement and slowly kills differentiated SH-SY5Y neural cells. | Molecular neurodegeneration 20080101 |
| Modifications of antiepileptic drugs for improved tolerability and efficacy. | Perspectives in medicinal chemistry 20080101 |
| Drug design with Cdc7 kinase: a potential novel cancer therapy target. | Drug design, development and therapy 20080101 |
| Development of a HTRF kinase assay for determination of Syk activity. | Current chemical genomics 20080101 |
| Fluorescent cascade and direct assays for characterization of RAF signaling pathway inhibitors. | Current chemical genomics 20080101 |
| Cellular Ser/Thr-kinase assays using generic peptide substrates. | Current chemical genomics 20080101 |
| Roles of prohibitin in growth control and tumor suppression in human cancers. | Translational oncogenomics 20080101 |
| Negative regulation of inducible nitric-oxide synthase expression mediated through transforming growth factor-beta-dependent modulation of transcription factor TCF11. | The Journal of biological chemistry 20071221 |
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. | Proceedings of the National Academy of Sciences of the United States of America 20071218 |
| Uniform sensitivity of FLT3 activation loop mutants to the tyrosine kinase inhibitor midostaurin. | Blood 20071215 |
| Staurosporine sensitizes T lymphoma cells to glucocorticoid-induced apoptosis: role of Nur77 and Bcl-2. | Cell cycle (Georgetown, Tex.) 20071215 |
| Betulinic acid, a catalytic inhibitor of topoisomerase I, inhibits reactive oxygen species-mediated apoptotic topoisomerase I-DNA cleavable complex formation in prostate cancer cells but does not affect the process of cell death. | Cancer research 20071215 |
| Isoform-specific translocation of PKC isoforms in NIH3T3 cells by TPA. | Biochemical and biophysical research communications 20071214 |
| Role of TASK2 in the control of apoptotic volume decrease in proximal kidney cells. | The Journal of biological chemistry 20071214 |
| Deubiquitination of FANCD2 is required for DNA crosslink repair. | Molecular cell 20071214 |
| Metal-based paullones as putative CDK inhibitors for antitumor chemotherapy. | Journal of medicinal chemistry 20071213 |
| Synaptic vesicle mobility in mouse motor nerve terminals with and without synapsin. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20071212 |
| RGDS peptides immobilized on titanium alloy stimulate bone cell attachment, differentiation and confer resistance to apoptosis. | Journal of biomedical materials research. Part A 20071201 |
| Notch3 activation modulates cell growth behaviour and cross-talk to Wnt/TCF signalling pathway. | Cellular signalling 20071201 |
| FLT3 regulates beta-catenin tyrosine phosphorylation, nuclear localization, and transcriptional activity in acute myeloid leukemia cells. | Leukemia 20071201 |
| K252a prevents nigral dopaminergic cell death induced by 6-hydroxydopamine through inhibition of both mixed-lineage kinase 3/c-Jun NH2-terminal kinase 3 (JNK3) and apoptosis-inducing kinase 1/JNK3 signaling pathways. | Molecular pharmacology 20071201 |
| Monoamine oxidase-A modulates apoptotic cell death induced by staurosporine in human neuroblastoma cells. | Journal of neurochemistry 20071201 |
| Intracellular K(+) inhibits apoptosis by suppressing the Apaf-1 apoptosome formation and subsequent downstream pathways but not cytochrome c release. | Cell death and differentiation 20071201 |
| Hierarchical recruitment by AMPA but not staurosporine of pro-apoptotic mitochondrial signaling in cultured cortical neurons: evidence for caspase-dependent/independent cross-talk. | Journal of neurochemistry 20071201 |
| The regulation of M1 muscarinic acetylcholine receptor desensitization by synaptic activity in cultured hippocampal neurons. | Journal of neurochemistry 20071201 |
| Effect of protein kinase C and Ca(2+) on p42/p44 MAPK, Pyk2, and Src activation in rat conjunctival goblet cells. | Experimental eye research 20071201 |
| Crystal structures of the N-terminal kinase domain of human RSK1 bound to three different ligands: Implications for the design of RSK1 specific inhibitors. | Protein science : a publication of the Protein Society 20071201 |
| Hyperosmotic stress-induced caspase-3 activation is mediated by p38 MAPK in the hippocampus. | Brain research 20071201 |
| Signaling molecules involved in IFN-gamma-inducible nitric oxide synthase expression in the mouse trophoblast. | American journal of reproductive immunology (New York, N.Y. : 1989) 20071201 |
| Evidence for a major role of endogenous fibroblast growth factor-2 in apoptotic cortex-induced subventricular zone cell proliferation. | The European journal of neuroscience 20071201 |
| Identification of driver and passenger mutations of FLT3 by high-throughput DNA sequence analysis and functional assessment of candidate alleles. | Cancer cell 20071201 |
| A novel inhibitory mechanism of mitochondrion-dependent apoptosis by a herpesviral protein. | PLoS pathogens 20071201 |
| p53-dependent Chk1 phosphorylation is required for maintenance of prolonged G2 Arrest. | Radiation research 20071201 |
| P-glycoprotein4 displays auxin efflux transporter-like action in Arabidopsis root hair cells and tobacco cells. | The Plant cell 20071201 |
| FLT3 kinase inhibitors in the management of acute myeloid leukemia. | Clinical lymphoma & myeloma 20071201 |
| Stimulation of extracellular signal-regulated kinases and proliferation in the human gastric cancer cells KATO-III by obestatin. | Growth factors (Chur, Switzerland) 20071201 |
| Regulation of mitochondrial Smac/DIABLO-selective release by survivin. | Oncogene 20071129 |
| Mitofusin 2 triggers vascular smooth muscle cell apoptosis via mitochondrial death pathway. | Circulation research 20071126 |
| Ca(2+)-dependent glycolysis activation mediates apoptotic ATP elevation in HeLa cells. | Biochemical and biophysical research communications 20071123 |
| Glial cell line-derived neurotrophic factor protects astrocytes from staurosporine- and ischemia- induced apoptosis. | Journal of neuroscience research 20071115 |
| Gini coefficient: a new way to express selectivity of kinase inhibitors against a family of kinases. | Journal of medicinal chemistry 20071115 |
| Synthesis and biological evaluation of a fluorine-18 derivative of dasatinib. | Journal of medicinal chemistry 20071115 |
| Alpha 1-adrenoceptor agonists protect against stress-induced death of neural progenitor cells. | European journal of pharmacology 20071114 |
| Tethering small molecules to a phage display library: discovery of a selective bivalent inhibitor of protein kinase A. | Journal of the American Chemical Society 20071114 |
| Protein kinase C epsilon regulates gamma-aminobutyrate type A receptor sensitivity to ethanol and benzodiazepines through phosphorylation of gamma2 subunits. | The Journal of biological chemistry 20071109 |
| Role of inositol 1,4,5-trisphosphate receptors in apoptosis in DT40 lymphocytes. | The Journal of biological chemistry 20071109 |
| AG490 influences UCN-01-induced cytotoxicity in glioma cells in a p53-dependent fashion, correlating with effects on BAX cleavage and BAD phosphorylation. | Cancer letters 20071108 |
| Protein kinase C activity in mouse eggs regulates gamete membrane interaction. | Molecular reproduction and development 20071101 |
| Effect of hypothalamic proline-rich peptide (PRP-1) on neuronal and bone marrow cell apoptosis. | Neurochemical research 20071101 |
| SAFB re-distribution marks steps of the apoptotic process. | Experimental cell research 20071101 |
| Alpha2-adrenergic receptors activate cyclic AMP-response element-binding protein through arachidonic acid metabolism and protein kinase A in a subtype-specific manner. | Journal of neurochemistry 20071101 |
| Regulation of VASP serine 157 phosphorylation in human neutrophils after stimulation by a chemoattractant. | Journal of leukocyte biology 20071101 |
| Apoptosis induced by direct triggering of mitochondrial apoptosis proceeds in the near-absence of some apoptotic markers. | Apoptosis : an international journal on programmed cell death 20071101 |
| An Hg-sensitive channel mediates the diffusional component of glucose transport in olive cells. | Biochimica et biophysica acta 20071101 |
| Functional implications of caspase-mediated RhoGDI2 processing during apoptosis of HL60 and K562 leukemia cells. | Apoptosis : an international journal on programmed cell death 20071101 |
| Induction of axon and dendrite formation during early RGC-5 cell differentiation. | Experimental eye research 20071101 |
| T cell independent mechanism for copolymer-1-induced neuroprotection. | European journal of immunology 20071101 |
| Polyploidization of 2nH1 (ES) cells by K-252a and staurosporine. | Human cell 20071101 |
| Chemotherapeutic agents up-regulate the cytomegalovirus promoter: implications for bioluminescence imaging of tumor response to therapy. | Cancer research 20071101 |
| Protein kinase C is an important signaling mediator associated with motility of intact sea urchin spermatozoa. | The Journal of experimental biology 20071101 |
| Discovery of lactoquinomycin and related pyranonaphthoquinones as potent and allosteric inhibitors of AKT/PKB: mechanistic involvement of AKT catalytic activation loop cysteines. | Molecular cancer therapeutics 20071101 |
| Inhibition of microparticle release triggers endothelial cell apoptosis and detachment. | Thrombosis and haemostasis 20071101 |
| Restoration of impaired phosphorylation of cyclic AMP response element-binding protein (CREB) by EGb 761 and its constituents in Abeta-expressing neuroblastoma cells. | The European journal of neuroscience 20071101 |
| Synergistic growth-inhibitory effects of two tyrosine kinase inhibitors, dasatinib and PKC412, on neoplastic mast cells expressing the D816V-mutated oncogenic variant of KIT. | Haematologica 20071101 |
| Role of mutation independent constitutive activation of FLT3 in juvenile myelomonocytic leukemia. | Haematologica 20071101 |
| Mitochondrial regulation of caspase activation by cytochrome oxidase and tetramethylphenylenediamine via cytosolic cytochrome c redox state. | The Journal of biological chemistry 20071026 |
| Neuroprotective function of thymosin-beta and its derivative peptides on the programmed cell death of chick and rat neurons. | Biochemical and biophysical research communications 20071026 |
| Connexin 43 confers resistance to hydrogen peroxide-mediated apoptosis. | Biochemical and biophysical research communications 20071026 |
| JAK2 tyrosine kinase phosphorylates PAK1 and regulates PAK1 activity and functions. | The Journal of biological chemistry 20071019 |
| Suppression of staurosporine-mediated apoptosis in Hs578T breast cells through inhibition of neutral-sphingomyelinase by caveolin-1. | Cancer letters 20071018 |
| Use of a chemical genetic technique to identify myosin IIb as a substrate of the Abl-related gene (Arg) tyrosine kinase. | Biochemistry 20071016 |
| Structural and functional characterization of the human protein kinase ASK1. | Structure (London, England : 1993) 20071016 |
| Small interfering RNA-mediated silencing of mitochondrial NADP+-dependent isocitrate dehydrogenase enhances the sensitivity of HeLa cells toward tumor necrosis factor-alpha and anticancer drugs. | Free radical biology & medicine 20071015 |
| Sensitization of osteosarcoma cells to apoptosis by oncostatin M depends on STAT5 and p53. | Oncogene 20071011 |
| Bim expression indicates the pathway to retinal cell death in development and degeneration. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20071003 |
| Endosulfan decreases cell growth and apoptosis in human HaCaT keratinocytes: partial ROS-dependent ERK1/2 mechanism. | Journal of cellular physiology 20071001 |
| The effect of simulated microgravity on osteoblasts is independent of the induction of apoptosis. | Journal of cellular biochemistry 20071001 |
| Induction of EROD activity by 1-phenylimidazole and beta-naphthoflavone in rainbow trout cultured hepatocytes: a comparative study. | Toxicology in vitro : an international journal published in association with BIBRA 20071001 |
| Trypanosoma cruzi epimastigotes: regulation of myo-inositol transport by effectors of protein kinases A and C. | Experimental parasitology 20071001 |
| Involvement of protein kinase C and IP3-mediated Ca2+ release in activity modulation by paraoxon in snail neurons. | European journal of pharmacology 20071001 |
| Staurosporine-induced cell death in salmonid cells: the role of apoptotic volume decrease, ion fluxes and MAP kinase signaling. | Apoptosis : an international journal on programmed cell death 20071001 |
| Gamma-glutamylcysteine synthetase mediates the c-Myc-dependent response to antineoplastic agents in melanoma cells. | Molecular pharmacology 20071001 |
| No upregulation of lectin-like oxidized low-density lipoprotein receptor-1 in serum-deprived EA.hy926 endothelial cells under oxLDL exposure, but increase in autophagy. | European journal of cell biology 20071001 |
| PKC 412 small-molecule tyrosine kinase inhibitor: single-compound therapy for pancreatic cancer. | Cancer 20071001 |
| Cystein cathepsin and Hsp90 activities determine the balance between apoptotic and necrotic cell death pathways in caspase-compromised U937 cells. | Biochimica et biophysica acta 20071001 |
| Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death. | EMBO reports 20071001 |
| Sensitivity toward sorafenib and sunitinib varies between different activating and drug-resistant FLT3-ITD mutations. | Experimental hematology 20071001 |
| Assessment of rat and mouse RGC apoptosis imaging in vivo with different scanning laser ophthalmoscopes. | Current eye research 20071001 |
| Rapid and drastic induction of CYP3A4 mRNA expression via vitamin D receptor in human intestinal LS180 cells. | Drug metabolism and pharmacokinetics 20071001 |
| Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20070926 |
| MEK1/2 inhibitors potentiate UCN-01 lethality in human multiple myeloma cells through a Bim-dependent mechanism. | Blood 20070915 |
| Nonclassic functions of human topoisomerase I: genome-wide and pharmacologic analyses. | Cancer research 20070915 |
| Nonenzymatic oxidative steps accompanying action of the cytochrome P450 enzymes StaP and RebP in the biosynthesis of staurosporine and rebeccamycin. | Journal of the American Chemical Society 20070912 |
| Binding of TPX2 to Aurora A alters substrate and inhibitor interactions. | Biochemistry 20070911 |
| Synergistic effects of combined cytotoxic and apoptosis-inducing drugs on Tenon's capsule fibroblasts in vitro and in vivo. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20070901 |
| Mitochondrial-targeted active Akt protects SH-SY5Y neuroblastoma cells from staurosporine-induced apoptotic cell death. | Journal of cellular biochemistry 20070901 |
| Oxidative stress enhances phosphorylation of p53 in neonatal rat cardiomyocytes. | Molecular and cellular biochemistry 20070901 |
| A point mutation in the putative ATP binding site of the pseudorabies virus US3 protein kinase prevents Bad phosphorylation and cell survival following apoptosis induction. | Virus research 20070901 |
| The role of alpha-, beta-, and gamma-ENaC subunits in distal lung epithelial fluid absorption induced by pulmonary edema fluid. | American journal of physiology. Lung cellular and molecular physiology 20070901 |
| Lysophosphatidylcholine produced by the phospholipase A2 isolated from Lachesis muta snake venom modulates natural killer activity as a protein kinase C effector. | Toxicon : official journal of the International Society on Toxinology 20070901 |
| Characterization of a eukaryotic type serine/threonine kinase in Spodoptera litura nucleopolyhedrovirus-I (SpltNPV-I). | Virus research 20070901 |
| Rapid down-regulation of Ret following exposure of dopaminergic neurons to neurotoxins. | Journal of neurochemistry 20070901 |
| Cross-talking between 5-HT3 and GABAA receptors in cultured myenteric neurons. | Synapse (New York, N.Y.) 20070901 |
| Alteration of NF-kappaB activity leads to mitochondrial apoptosis after infection with pathological prion protein. | Cellular microbiology 20070901 |
| A fluorescence lifetime based binding assay to characterize kinase inhibitors. | Journal of biomolecular screening 20070901 |
| A comparison of three flow cytometry methods for evaluating mitochondrial damage during staurosporine-induced apoptosis in Jurkat cells. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20070901 |
| Apoptosis induced by staurosporine alters chaperone and endoplasmic reticulum proteins: Identification by quantitative proteomics. | Proteomics 20070901 |
| Proteomic and biochemical studies of calcium- and phosphorylation-dependent calmodulin complexes in Mammalian cells. | Journal of proteome research 20070901 |
| Terrequinone A biosynthesis through L-tryptophan oxidation, dimerization and bisprenylation. | Nature chemical biology 20070901 |
| CD154 induces a switch in pro-survival Bcl-2 family members in chronic lymphocytic leukaemia. | British journal of haematology 20070901 |
| Vascular pharmacology of mokuboito (mu-fang-yi-tang) and its constituents on the smooth muscle and the endothelium in rat aorta. | Evidence-based complementary and alternative medicine : eCAM 20070901 |
| Lack of evidence for direct phosphorylation of recombinantly expressed P2X(2) and P2X (3) receptors by protein kinase C. | Purinergic signalling 20070901 |
| Guanosine reduces apoptosis and inflammation associated with restoration of function in rats with acute spinal cord injury. | Purinergic signalling 20070901 |
| Allosteric modulation of muscarinic acetylcholine receptors. | Current neuropharmacology 20070901 |
| Rosiglitazone attenuates NF-kappaB-dependent ICAM-1 and TNF-alpha production caused by homocysteine via inhibiting ERK1/2/p38MAPK activation. | Biochemical and biophysical research communications 20070817 |
| Activation of protein phosphatase causes alternative splicing of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL): potential effect on immune surveillance. | Biochemical and biophysical research communications 20070817 |
| PKC412 (CGP41251) modulates the proliferation and lipopolysaccharide-induced inflammatory responses of RAW 264.7 macrophages. | Biochemical and biophysical research communications 20070817 |
| Estrogen receptor alpha inhibits p53-mediated transcriptional repression: implications for the regulation of apoptosis. | Cancer research 20070815 |
| Abeta42 neurotoxicity in primary co-cultures: effect of apoE isoform and Abeta conformation. | Neurobiology of aging 20070801 |
| Down-regulation of neuropathy target esterase by protein kinase C activation with PMA stimulation. | Molecular and cellular biochemistry 20070801 |
| Active caspase-3 and ultrastructural evidence of apoptosis in spontaneous and induced cell death in bovine in vitro produced pre-implantation embryos. | Molecular reproduction and development 20070801 |
| Neuroprotective effect of ganglioside GM1 on the cytotoxic action of hydrogen peroxide and amyloid beta-peptide in PC12 cells. | Neurochemical research 20070801 |
| The cell cycle inhibitor p57(Kip2) promotes cell death via the mitochondrial apoptotic pathway. | Cell death and differentiation 20070801 |
| Inhibition of deoxyribonuclease I by actin is to protect cells from premature cell death. | Apoptosis : an international journal on programmed cell death 20070801 |
| Mitochondrial glutathione protects against cell death induced by oxidative and nitrative stress in astrocytes. | Journal of neurochemistry 20070801 |
| UCN-01 in combination with topotecan in patients with advanced recurrent ovarian cancer: a study of the Princess Margaret Hospital Phase II consortium. | Gynecologic oncology 20070801 |
| Blockade of adenosine A(2A) receptors prevents staurosporine-induced apoptosis of rat hippocampal neurons. | Neurobiology of disease 20070801 |
| Survival improvement in thoracic cancer: progress from the last decade and beyond. | Lung cancer (Amsterdam, Netherlands) 20070801 |
| Selective cell death of oncogenic Akt-transduced brain cancer cells by etoposide through reactive oxygen species mediated damage. | Molecular cancer therapeutics 20070801 |
| The phosphoinositide 3-kinase pathway in human cancer: genetic alterations and therapeutic implications. | Current genomics 20070801 |
| The hepatitis E virus Orf3 protein protects cells from mitochondrial depolarization and death. | The Journal of biological chemistry 20070720 |
| Calcium ionophore-induced egress of Toxoplasma gondii shortly after host cell invasion. | Veterinary parasitology 20070720 |
| Mechanism of membrane redistribution of protein kinase C by its ATP-competitive inhibitors. | The Biochemical journal 20070715 |
| A homogeneous assay to measure live and dead cells in the same sample by detecting different protease markers. | Analytical biochemistry 20070715 |
| PAN-811 provides neuroprotection against glutamate toxicity by suppressing activation of JNK and p38 MAPK. | Neuroscience letters 20070705 |
| The role of mitochondrial reactive oxygen species in pH regulation in articular chondrocytes. | Osteoarthritis and cartilage 20070701 |
| Regulation of human organic anion transporter 4 by progesterone and protein kinase C in human placental BeWo cells. | American journal of physiology. Endocrinology and metabolism 20070701 |
| The CC chemokine ligand 2 (CCL2) mediates fibroblast survival through IL-6. | American journal of respiratory cell and molecular biology 20070701 |
| Genetic organization of the biosynthetic gene cluster for the indolocarbazole K-252a in Nonomuraea longicatena JCM 11136. | Applied microbiology and biotechnology 20070701 |
| Bfk, a novel member of the bcl2 gene family, is highly expressed in principal cells of the mouse epididymis and demonstrates a predominant nuclear localization. | Endocrinology 20070701 |
| Sphingosine 1-phosphate mediates proliferation and survival of mesoangioblasts. | Stem cells (Dayton, Ohio) 20070701 |
| Basic fibroblast growth factor: lysine 134 is essential for its neuroprotective activity. | Neurochemistry international 20070701 |
| Activation of inwardly rectifying Kir2.x potassium channels by beta 3-adrenoceptors is mediated via different signaling pathways with a predominant role of PKC for Kir2.1 and of PKA for Kir2.2. | Naunyn-Schmiedeberg's archives of pharmacology 20070701 |
| Potentiation of antileukemic therapies by Smac mimetic, LBW242: effects on mutant FLT3-expressing cells. | Molecular cancer therapeutics 20070701 |
| 2-Methoxy antimycin reveals a unique mechanism for Bcl-x(L) inhibition. | Molecular cancer therapeutics 20070701 |
| [Protective effects of nourishing spleen yin recipe on endoplasmic reticulum stress-induced neuronal cell damage and its mechanism]. | Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20070701 |
| Acquisition of apoptotic resistance in cadmium-transformed human prostate epithelial cells: Bcl-2 overexpression blocks the activation of JNK signal transduction pathway. | Environmental health perspectives 20070701 |
| Mitochondrial cell death control in familial Parkinson disease. | PLoS biology 20070701 |
| Vasorelaxing effect of the Rho-kinase inhibitor, Y-27632, in isolated canine basilar arteries. | Neurological research 20070701 |
| Various Molecular Species of Diacylglycerol Hydroperoxide Activate Human Neutrophils via PKC Activation. | Journal of clinical biochemistry and nutrition 20070701 |
| Propofol reverses oxidative stress-attenuated glutamate transporter EAAT3 activity: evidence of protein kinase C involvement. | European journal of pharmacology 20070622 |
| In vitro micronucleus assay scored by flow cytometry provides a comprehensive evaluation of cytogenetic damage and cytotoxicity. | Mutation research 20070615 |
| A rapid inhibition of NMDA receptor current by corticosterone in cultured hippocampal neurons. | Neuroscience letters 20070615 |
| Signal transduction pathways of GM-CSF in neural cell lines. | Neuroscience letters 20070615 |
| Phosphorylation of Ser166 in RGS5 by protein kinase C causes loss of RGS function. | Life sciences 20070613 |
| Protein kinase C inhibition attenuates hypochlorite-induced acute lung injury. | Respiratory medicine 20070601 |
| Gastrin regulates the TFF2 promoter through gastrin-responsive cis-acting elements and multiple signaling pathways. | American journal of physiology. Gastrointestinal and liver physiology 20070601 |
| Novel neuroprotective compound SCH-20148 rescues thymocytes and SH-SY5Y cells from thapsigargin-induced mitochondrial membrane potential reduction and cell death. | European journal of pharmacology 20070601 |
| Potential effects of PKC or protease inhibitors on acute pancreatitis-induced tissue injury in rats. | Vascular pharmacology 20070601 |
| PKC and polyamine modulation of GluR2-deficient AMPA receptors in immature neocortical pyramidal neurons of the rat. | The Journal of physiology 20070601 |
| Golgi complex disassembly caused by light-activated calphostin C involves MAPK and PKA. | Tissue & cell 20070601 |
| Norepinephrine, via beta-adrenoceptors, regulates bumetanide-sensitive cotransporter type 1 expression in thick ascending limb cells. | Hypertension (Dallas, Tex. : 1979) 20070601 |
| Nerve growth factor mediates steroid-resistant inflammation in respiratory syncytial virus infection. | Pediatric pulmonology 20070601 |
| Functional and structural studies of the vaccinia virus virulence factor N1 reveal a Bcl-2-like anti-apoptotic protein. | The Journal of general virology 20070601 |
| Histone deacetylase inhibition-mediated differentiation of RGC-5 cells and interaction with survival. | Investigative ophthalmology & visual science 20070601 |
| Chemically standardized isolates from Cedrus deodara stem wood having anticancer activity. | Planta medica 20070601 |
| Broad spectrum neuroprotection profile of phosphodiesterase inhibitors as related to modulation of cell-cycle elements and caspase-3 activation. | Neuroscience letters 20070517 |
| Curcumin-induced GADD153 upregulation: modulation by glutathione. | Journal of cellular biochemistry 20070515 |
| Proliferation of human breast cancer cells and anti-cancer action of doxorubicin and vinblastine are independent of PKC-alpha. | Journal of cellular biochemistry 20070515 |
| Statins synergistically potentiate 7-hydroxystaurosporine (UCN-01) lethality in human leukemia and myeloma cells by disrupting Ras farnesylation and activation. | Blood 20070515 |
| Protein kinase C activity affects neurotransmitter release at polyinnervated neuromuscular synapses. | Journal of neuroscience research 20070515 |
| Involvement of heat shock protein (Hsp)90 beta but not Hsp90 alpha in antiapoptotic effect of CpG-B oligodeoxynucleotide. | Journal of immunology (Baltimore, Md. : 1950) 20070515 |
| Myeloid cell leukemia-1 inversely correlates with glycogen synthase kinase-3beta activity and associates with poor prognosis in human breast cancer. | Cancer research 20070515 |
| Glutathione export during apoptosis requires functional multidrug resistance-associated proteins. | The Journal of biological chemistry 20070511 |
| Staurosporine-induced apoptosis in astrocytes is prevented by A1 adenosine receptor activation. | Neuroscience letters 20070511 |
| Role of mitochondrial remodeling in programmed cell death in Drosophila melanogaster. | Developmental cell 20070508 |
| A purified extract from Clematis mandshurica prevents staurosporin-induced downregulation of 14-3-3 and subsequent apoptosis on rat chondrocytes. | Journal of ethnopharmacology 20070504 |
| Clusterin is protective in pancreatitis through anti-apoptotic and anti-inflammatory properties. | Biochemical and biophysical research communications 20070504 |
| Effects of OPA1 mutations on mitochondrial morphology and apoptosis: relevance to ADOA pathogenesis. | Journal of cellular physiology 20070501 |
| Dopamine stimulates 45Ca2+ uptake through cAMP, PLC/PKC, and MAPKs in renal proximal tubule cells. | Journal of cellular physiology 20070501 |
| Effect of NYD-SP27 down-regulation on ATP-induced Ca2+-dependent pancreatic duct anion secretion in cystic fibrosis cells. | Cell biology international 20070501 |
| Shrinkage insensitivity of NKCC1 in myosin II-depleted cytoplasts from Ehrlich ascites tumor cells. | American journal of physiology. Cell physiology 20070501 |
| Failure of stress-induced downregulation of Bcl-2 contributes to apoptosis resistance in senescent human diploid fibroblasts. | Cell death and differentiation 20070501 |
| Divergent cytotoxic effects of PKC412 in combination with conventional antileukemic agents in FLT3 mutation-positive versus -negative leukemia cell lines. | Leukemia 20070501 |
| GM-CSF inhibits apoptosis of neural cells via regulating the expression of apoptosis-related proteins. | Neuroscience research 20070501 |
| Smac-mediated sensitization of human B-lymphoma cells to staurosporine- and lactacystin-triggered apoptosis is apoptosome-dependent. | Leukemia 20070501 |
| Staurosporine differentiation of NPFF2 receptor-transfected SH-SY5Y neuroblastoma cells induces selectivity of NPFF activity towards opioid receptors. | Peptides 20070501 |
| Metalloproteinase 9 is the outer executioner of desmoglein 3 in apoptotic keratinocytes. | Oral diseases 20070501 |
| Phase I and pharmacokinetic study of 7-hydroxystaurosporine and carboplatin in advanced solid tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070501 |
| [Regulatory effect of protein kinase C and protein kinase G on calcium sensitivity of vascular smooth muscle cells following hemorrhagic shock]. | Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20070501 |
| Inhibition of topoisomerase IIalpha and G2 cell cycle arrest by NK314, a novel benzo[c]phenanthridine currently in clinical trials. | Molecular cancer therapeutics 20070501 |
| [Research on cyclin-dependent kinase inhibitors: state of the art and perspective]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20070501 |
| Activation of silent synapses with sustained but not decremental long-term potentiation. | Neuroscience letters 20070424 |
| Platinum complex as a nanomolar protein kinase inhibitor. | Inorganic chemistry 20070416 |
| alpha(1)-Acid glycoprotein modulates apoptosis in bovine monocytes. | Veterinary immunology and immunopathology 20070415 |
| Characterization of apoptotic pathway associated with caspase-independent excision of DNA loop domains. | Experimental cell research 20070415 |
| Effects of NGF and BDNF on baseline glutamate and dopamine release in the hippocampal formation of the adult rat. | Brain research 20070413 |
| Serine protease Omi/HtrA2 targets WARTS kinase to control cell proliferation. | Oncogene 20070412 |
| p53-Dependent Aph-1 and Pen-2 anti-apoptotic phenotype requires the integrity of the gamma-secretase complex but is independent of its activity. | The Journal of biological chemistry 20070406 |
| Identification of MCL1 as a novel target in neoplastic mast cells in systemic mastocytosis: inhibition of mast cell survival by MCL1 antisense oligonucleotides and synergism with PKC412. | Blood 20070401 |
| Nerve growth factor acutely potentiates synaptic transmission in vitro and induces dendritic growth in vivo on adult neurons in airway parasympathetic ganglia. | American journal of physiology. Lung cellular and molecular physiology 20070401 |
| Role of myosin regulatory light chain and Rac1 in the migration of polyamine-depleted intestinal epithelial cells. | American journal of physiology. Gastrointestinal and liver physiology 20070401 |
| Toxoplasma gondii glycosylphosphatidylinositols are not involved in T. gondii-induced host cell survival. | Apoptosis : an international journal on programmed cell death 20070401 |
| IAP survivin regulates atherosclerotic macrophage survival. | Arteriosclerosis, thrombosis, and vascular biology 20070401 |
| Cellular processes and pathways that protect Saccharomyces cerevisiae cells against the plasma membrane-perturbing compound chitosan. | Eukaryotic cell 20070401 |
| Hypericin activates L-type Ca2+ channels in cardiac myocytes. | Journal of natural products 20070401 |
| Analysis of the monovalent ion fluxes in U937 cells under the balanced ion distribution: recognition of ion transporters responsible for changes in cell ion and water balance during apoptosis. | Cell biology international 20070401 |
| Elicitin-responsive lectin-like receptor kinase genes in BY-2 cells. | DNA sequence : the journal of DNA sequencing and mapping 20070401 |
| Fluorescent determination of cardiolipin using 10-N-nonyl acridine orange. | Analytical and bioanalytical chemistry 20070401 |
| Inhibition of plasminogen activators attenuates the death of differentiated retinal ganglion cells and stabilizes their neurite network in vitro. | Investigative ophthalmology & visual science 20070401 |
| Effects of JC virus infection on anti-apoptotic protein survivin in progressive multifocal leukoencephalopathy. | The American journal of pathology 20070401 |
| Fragmentation of the Golgi apparatus: an early apoptotic event independent of the cytoskeleton. | Traffic (Copenhagen, Denmark) 20070401 |
| Overexpression of Wnt-1 in thyrocytes enhances cellular growth but suppresses transcription of the thyroperoxidase gene via different signaling mechanisms. | The Journal of endocrinology 20070401 |
| The dynamics of the rapsyn scaffolding protein at individual acetylcholine receptor clusters. | The Journal of biological chemistry 20070330 |
| Activation mechanism and steady state kinetics of Bruton's tyrosine kinase. | The Journal of biological chemistry 20070323 |
| Homology modeling of human Fyn kinase structure: discovery of rosmarinic acid as a new Fyn kinase inhibitor and in silico study of its possible binding modes. | Journal of medicinal chemistry 20070322 |
| Synthesis of N-protected staurosporinones. | The Journal of organic chemistry 20070316 |
| Functional role of beta-adrenergic receptors in the mitogenic action of nicotine on gastric cancer cells. | Toxicological sciences : an official journal of the Society of Toxicology 20070301 |
| A 'classical' homodimeric erythropoietin receptor is essential for the antiapoptotic effects of erythropoietin on differentiated neuroblastoma SH-SY5Y and pheochromocytoma PC-12 cells. | Cellular signalling 20070301 |
| Different phosphorylation mechanisms are involved in the activation of sucrose non-fermenting 1 related protein kinases 2 by osmotic stresses and abscisic acid. | Plant molecular biology 20070301 |
| Adeno-associated virus 2-mediated gene transfer: role of a cellular serine/threonine protein phosphatase in augmenting transduction efficiency. | Gene therapy 20070301 |
| Potent stimulation of large-conductance Ca2+-activated K+ channels by rottlerin, an inhibitor of protein kinase C-delta, in pituitary tumor (GH3) cells and in cortical neuronal (HCN-1A) cells. | Journal of cellular physiology 20070301 |
| Nerve growth factor enhances voltage-gated Na+ channel activity and Transwell migration in Mat-LyLu rat prostate cancer cell line. | Journal of cellular physiology 20070301 |
| Herpes simplex virus-type 2 infectivity and agents that block gap junctional intercellular communication. | Virus research 20070301 |
| Up-regulation of 150-kDa oxygen-regulated protein by celecoxib in human gastric carcinoma cells. | Molecular pharmacology 20070301 |
| Neuroprotective efficacy of the peroxisome proliferator-activated receptor delta-selective agonists in vitro and in vivo. | The Journal of pharmacology and experimental therapeutics 20070301 |
| Apoptosis in early development of the sea urchin, Strongylocentrotus purpuratus. | Developmental biology 20070301 |
| Sustained activation of proton channels and NADPH oxidase in human eosinophils and murine granulocytes requires PKC but not cPLA2 alpha activity. | The Journal of physiology 20070301 |
| Mitochondria are not required for death receptor-mediated cytosolic acidification during apoptosis. | Apoptosis : an international journal on programmed cell death 20070301 |
| Acetaminophen potentiates staurosporine-induced death in a human neuroblastoma cell line. | British journal of pharmacology 20070301 |
| Involvement of Ca2+- and cyclic adenosine monophosphate-mediated signaling pathways in photodynamic injury of isolated crayfish neuron and satellite glial cells. | Journal of neuroscience research 20070301 |
| UCN-01 (7-hydroxystaurosporine) induces apoptosis and G1 arrest of both primary and metastatic oral cancer cell lines in vitro. | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20070301 |
| The EGF receptor Hokey-Cokey. | Cancer cell 20070301 |
| Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity. | Cancer cell 20070301 |
| Caspase-14: a new player in cytotrophoblast differentiation. | Reproductive biomedicine online 20070301 |
| Resistance to c-KIT kinase inhibitors conferred by V654A mutation. | Molecular cancer therapeutics 20070301 |
| Some biochemical properties of the upregulation of the squid nerve Na+/Ca2+ exchanger by MgATP and phosphoarginine. | Annals of the New York Academy of Sciences 20070301 |
| Apical localization of glutamate in GLAST-1, glutamine synthetase positive ciliary body nonpigmented epithelial cells. | Clinical ophthalmology (Auckland, N.Z.) 20070301 |
| PKC412 demonstrates JNK-dependent activity against human multiple myeloma cells. | Blood 20070215 |
| Ligusticum chuanxiong prevents rat pheochromocytoma cells from serum deprivation-induced apoptosis through a protein kinase A-dependent pathway. | Journal of ethnopharmacology 20070212 |
| Synthesis and mixed lineage kinase activity of pyrrolocarbazole and isoindolone analogs of (+)K-252a. | Journal of medicinal chemistry 20070208 |
| Apoptosis is induced in leishmanial cells by a novel protein kinase inhibitor withaferin A and is facilitated by apoptotic topoisomerase I-DNA complex. | Cell death and differentiation 20070201 |
| A nerve growth factor-induced retrograde survival signal mediated by mechanisms downstream of TrkA. | Neuropharmacology 20070201 |
| Both Ca2+ -dependent and -independent pathways are involved in rat hepatic stellate cell contraction and intrahepatic hyperresponsiveness to methoxamine. | American journal of physiology. Gastrointestinal and liver physiology 20070201 |
| L1-CAM in a membrane-bound or soluble form augments protection from apoptosis in ovarian carcinoma cells. | Gynecologic oncology 20070201 |
| Implication of PTEN in production of reactive oxygen species and neuronal death in in vitro models of stroke and Parkinson's disease. | Neurochemistry international 20070201 |
| Cleavage of MAGI-1, a tight junction PDZ protein, by caspases is an important step for cell-cell detachment in apoptosis. | Apoptosis : an international journal on programmed cell death 20070201 |
| Cyclic GMP-dependent pathways protect differentiated oligodendrocytes from multiple types of injury. | Neurochemical research 20070201 |
| Dephosphorylation of TORC initiates expression of the StAR gene. | Molecular and cellular endocrinology 20070201 |
| Effects of high-affinity nerve growth factor receptor inhibitors on symptoms in the NC/Nga mouse atopic dermatitis model. | The British journal of dermatology 20070201 |
| Caspase-dependent cleavage of desmoglein 1 depends on the apoptotic stimulus. | The British journal of dermatology 20070201 |
| Signaling pathways regulating IL-1alpha-induced COX-2 expression. | Journal of dental research 20070201 |
| Apoptotic DNA fragmentation is not related to the phosphorylation state of histone H1. | Biological chemistry 20070201 |
| p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage. | Cancer cell 20070201 |
| Crystal Structures of the p21-activated kinases PAK4, PAK5, and PAK6 reveal catalytic domain plasticity of active group II PAKs. | Structure (London, England : 1993) 20070201 |
| Transforming growth factor-beta1 up-regulates the expression of nerve growth factor through mitogen-activated protein kinase signaling pathways in dental pulp cells. | European journal of oral sciences 20070201 |
| A new inhibitor of apoptosis from vaccinia virus and eukaryotes. | PLoS pathogens 20070201 |
| Staurosporine inhibition of zipper-interacting protein kinase contractile effects in gastrointestinal smooth muscle. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20070201 |
| [Novel molecularly target therapies for leukemia]. | Nihon rinsho. Japanese journal of clinical medicine 20070128 |
| The C-terminal products of cellular prion protein processing, C1 and C2, exert distinct influence on p53-dependent staurosporine-induced caspase-3 activation. | The Journal of biological chemistry 20070119 |
| Functional interrogation of the kinome using nucleotide acyl phosphates. | Biochemistry 20070116 |
| Simplified staurosporine analogs as potent JAK3 inhibitors. | Bioorganic & medicinal chemistry letters 20070115 |
| In vitro cytotoxicity evaluation of some substituted isatin derivatives. | Bioorganic & medicinal chemistry 20070115 |
| A phase I trial of the selective oral cyclin-dependent kinase inhibitor seliciclib (CYC202; R-Roscovitine), administered twice daily for 7 days every 21 days. | British journal of cancer 20070115 |
| Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis. | The Journal of cell biology 20070115 |
| NO-1886, a lipoprotein lipase activator, attenuates vascular smooth muscle contraction in rat aorta. | European journal of pharmacology 20070112 |
| Involvement of protein kinase Cdelta in iron chelator-induced IL-8 production in human intestinal epithelial cells. | Life sciences 20070109 |
| Caspase-dependent and -independent induction of phosphatidylserine externalization during apoptosis in human renal carcinoma Cak(1)-1 and A-498 cells. | Toxicology 20070105 |
| The Trk tyrosine kinase inhibitor K252a regulates growth of lung adenocarcinomas. | Molecular and cellular biochemistry 20070101 |
| Characterization of cell clones isolated from hypoxia-selected renal proximal tubular cells. | American journal of physiology. Renal physiology 20070101 |
| FAP-1-mediated activation of NF-kappaB induces resistance of head and neck cancer to Fas-induced apoptosis. | Journal of cellular biochemistry 20070101 |
| Chondrocyte apoptosis is not essential for cartilage calcification: evidence from an in vitro avian model. | Journal of cellular biochemistry 20070101 |
| 7-Hydroxystaurosporine may have a therapeutic role in treatment-resistant depression by inhibition of calcium/calmodulin-dependent protein kinase II. | Medical hypotheses 20070101 |
| Overexpression of human 27 kDa heat shock protein in laryngeal cancer cells confers chemoresistance associated with cell growth delay. | Journal of cancer research and clinical oncology 20070101 |
| The neuropeptide pituitary adenylate cyclase activating protein stimulates human monocytes by transactivation of the Trk/NGF pathway. | Cellular signalling 20070101 |
| Staurosporine induces tyrosine phosphorylation in Dictyostelium discoideum proteins. | Cell biochemistry and function 20070101 |
| Activation of mitochondrial-driven apoptosis in skeletal muscle cells is not mediated by reactive oxygen species production. | The international journal of biochemistry & cell biology 20070101 |
| Mitogen activated protein kinase and protein kinase C activation mediate promotion of sAPPalpha secretion by deprenyl. | Neurochemistry international 20070101 |
| beta-Nerve growth factor participates in an auto/paracrine pathway of regulation of the meiotic differentiation of rat spermatocytes. | Journal of cellular physiology 20070101 |
| Estrogen modulation of MgATPase activity of nonmuscle myosin-II-B filaments. | Endocrinology 20070101 |
| Apoptosis of rat granulosa cells after staurosporine and serum withdrawal is suppressed by adenovirus-directed overexpression of prohibitin. | Endocrinology 20070101 |
| Role of quercetin and its in vivo metabolites in protecting H9c2 cells against oxidative stress. | Biochimie 20070101 |
| Bone marrow stromal cells mediate protection through stimulation of PI3-K/Akt and MAPK signaling in neurons. | Neurochemistry international 20070101 |
| Mitochondrial isocitrate dehydrogenase protects human neuroblastoma SH-SY5Y cells against oxidative stress. | Journal of neuroscience research 20070101 |
| Herpes simplex virus blocks apoptosis by precluding mitochondrial cytochrome c release independent of caspase activation in infected human epithelial cells. | Apoptosis : an international journal on programmed cell death 20070101 |
| Fusiogenic endogenous-retroviral syncytin-1 exerts anti-apoptotic functions in staurosporine-challenged CHO cells. | Apoptosis : an international journal on programmed cell death 20070101 |
| Mitochondrial control of cell death induced by hyperosmotic stress. | Apoptosis : an international journal on programmed cell death 20070101 |
| Eukaryotic initiation factor 4E variants alter the morphology, proliferation, and colony-formation properties of MDA-MB-435 cancer cells. | Molecular carcinogenesis 20070101 |
| Changes in gap junction organization and decreased coupling during induced apoptosis in lens epithelial and NIH-3T3 cells. | Experimental cell research 20070101 |
| Pinusolide and 15-methoxypinusolidic acid attenuate the neurotoxic effect of staurosporine in primary cultures of rat cortical cells. | British journal of pharmacology 20070101 |
| Structural biology contributions to the discovery of drugs to treat chronic myelogenous leukaemia. | Acta crystallographica. Section D, Biological crystallography 20070101 |
| Augmenting effect of serotonin on the voltage-dependent Ca2+ current and subsequently activated K+ current in Aplysia neurons. | The Tohoku journal of experimental medicine 20070101 |
| p53 transcription-dependent and -independent regulation of cerebellar neural precursor cell apoptosis. | Journal of neuropathology and experimental neurology 20070101 |
| Dendrimer-based targeted delivery of an apoptotic sensor in cancer cells. | Biomacromolecules 20070101 |
| Mechanisms of mitotic cell death induced by chemotherapy-mediated G2 checkpoint abrogation. | Cancer research 20070101 |
| HIF-1 regulation of chondrocyte apoptosis: induction of the autophagic pathway. | Autophagy 20070101 |
| Down-regulation of dopamine transporter by iron chelation in vitro is mediated by altered trafficking, not synthesis. | Journal of neurochemistry 20070101 |
| Cholesterol synthesis inhibitors protect against platelet-activating factor-induced neuronal damage. | Journal of neuroinflammation 20070101 |
| Signalling pathways involved in the control of sperm cell volume. | Reproduction (Cambridge, England) 20070101 |
| Effects of valproate on serotonin-induced intracellular calcium mobilization in human platelets. | Journal of psychiatry & neuroscience : JPN 20070101 |
| Caspase-mediated cleavage of the exosome subunit PM/Scl-75 during apoptosis. | Arthritis research & therapy 20070101 |
| Retrospective analysis of protein kinase C-beta (PKC-beta) expression in lymphoid malignancies and its association with survival in diffuse large B-cell lymphomas. | Biology direct 20070101 |
| Full length Bid is sufficient to induce apoptosis of cultured rat hippocampal neurons. | BMC cell biology 20070101 |
| A highly sensitive method for the detection of PKC412 (CGP41251) and its metabolites by high-performance liquid chromatography. | Journal of pharmacological and toxicological methods 20070101 |
| p42MAPK-mediated phosphorylation of xEIAP/XLX in Xenopus cytostatic factor-arrested egg extracts. | BMC biochemistry 20070101 |
| Involvement of ER stress in retinal cell death. | Molecular vision 20070101 |
| Monocyte-derived dendritic cells loaded with a mixture of apoptotic/necrotic melanoma cells efficiently cross-present gp100 and MART-1 antigens to specific CD8(+) T lymphocytes. | Journal of translational medicine 20070101 |
| Retinoblastoma protein prevents staurosporine-induced cell death in a retinoblastoma-defective human glioma cell line. | Pathobiology : journal of immunopathology, molecular and cellular biology 20070101 |
| The N-terminus and alpha-5, alpha-6 helices of the pro-apoptotic protein Bax, modulate functional interactions with the anti-apoptotic protein Bcl-xL. | BMC cell biology 20070101 |
| Adenosine arrests apoptosis in lymphocytes but not in phagocytes from primary leucocyte cultures of the teleost fish, Sparus aurata L. | Developmental and comparative immunology 20070101 |
| Reconstruction of the kinetochore: a prelude to meiosis. | Cell division 20070101 |
| Zfra affects TNF-mediated cell death by interacting with death domain protein TRADD and negatively regulates the activation of NF-kappaB, JNK1, p53 and WOX1 during stress response. | BMC molecular biology 20070101 |
| Structural and functional definition of the specificity of a novel caspase-3 inhibitor, Ac-DNLD-CHO. | BMC pharmacology 20070101 |
| Suicidal erythrocyte death following cellular K+ loss. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101 |
| Farber disease: clinical presentation, pathogenesis and a new approach to treatment. | Pediatric rheumatology online journal 20070101 |
| Effects of beta-adrenergic receptor antagonists on oxidative stress in purified rat retinal ganglion cells. | Molecular vision 20070101 |
| 15d-PGJ2 induces apoptosis of mouse oligodendrocyte precursor cells. | Journal of neuroinflammation 20070101 |
| Oxidative stress and diabetic retinopathy. | Experimental diabetes research 20070101 |
| Effect of protein kinase inhibitors on protein phosphorylation and germination of aerial spores from Streptomyces coelicolor. | Folia microbiologica 20070101 |
| Mapping correlated membrane pulsations and fluctuations in human cells. | Journal of molecular recognition : JMR 20070101 |
| PI3 kinase dependent stimulation of gastric acid secretion by dexamethasone. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101 |
| Inhibitory effects of 1,25-dihydroxyvitamin D3 and its low-calcemic analogues on staurosporine-induced apoptosis. | Pharmacological reports : PR 20070101 |
| Bench-to-bedside review: High-mobility group box 1 and critical illness. | Critical care (London, England) 20070101 |
| UV-B-induced signaling events leading to enhanced-production of catharanthine in Catharanthus roseus cell suspension cultures. | BMC plant biology 20070101 |
| Inhibition of HeLa Cell apoptosis by storage-protein 2. | Biotechnology progress 20070101 |
| HCCR-1, a novel oncogene, encodes a mitochondrial outer membrane protein and suppresses the UVC-induced apoptosis. | BMC cell biology 20070101 |
| Apoptosis is not the major death mechanism induced by celecoxib on rheumatoid arthritis synovial fibroblasts. | Arthritis research & therapy 20070101 |
| Identification of two novel activities of the Wnt signaling regulator Dickkopf 3 and characterization of its expression in the mouse retina. | BMC cell biology 20070101 |
| Carbachol-mediated pigment granule dispersion in retinal pigment epithelium requires Ca2+ and calcineurin. | BMC cell biology 20070101 |
| A ribosomal S-6 kinase-mediated signal to C/EBP-beta is critical for the development of liver fibrosis. | PloS one 20070101 |
| Cytoprotective effect of polysaccharide isolated from different mushrooms against 7-ketocholesterol induced damage in mouse liver cell line (BNL CL. 2). | Nutrition research and practice 20070101 |
| Cardiovascular pharmacology of sinomenine: the mechanical and electropharmacological actions. | Drug target insights 20070101 |
| The NHE1 Na+/H+ exchanger regulates cell survival by activating and targeting ezrin to specific plasma membrane domains. | Cellular and molecular biology (Noisy-le-Grand, France) 20061230 |
| Sevoflurane stimulates MAP kinase signal transduction through the activation of PKC alpha and betaII in fetal rat cerebral cortex cultured neuron. | Acta histochemica et cytochemica 20061228 |
| The Drosophila RASSF homolog antagonizes the hippo pathway. | Current biology : CB 20061219 |
| Effect of EGF on [3H]-thymidine incorporation and cell cycle regulatory proteins in primary cultured chicken hepatocytes: Involvement of Ca2+/PKC and MAPKs. | Journal of cellular biochemistry 20061215 |
| CpG-B oligodeoxynucleotide promotes cell survival via up-regulation of Hsp70 to increase Bcl-xL and to decrease apoptosis-inducing factor translocation. | The Journal of biological chemistry 20061215 |
| Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition. | Journal of medicinal chemistry 20061214 |
| Involvement of mitogen-activated protein kinases and protein kinase C in regulation of antioxidant response element activity in human keratinocytes. | Cancer letters 20061208 |
| New synthetic protocols for the preparation of unsymmetrical bisindoles. | Organic letters 20061207 |
| Inhibition of staurosporine-induced activation of the proapoptotic multidomain Bcl-2 proteins Bax and Bak by three invasive chlamydial species. | The Journal of infection 20061201 |
| Pyruvate and oxaloacetate limit zinc-induced oxidative HT-22 neuronal cell injury. | Neurotoxicology 20061201 |
| The extracellular release of HMGB1 during apoptotic cell death. | American journal of physiology. Cell physiology 20061201 |
| ATP stimulates mouse embryonic stem cell proliferation via protein kinase C, phosphatidylinositol 3-kinase/Akt, and mitogen-activated protein kinase signaling pathways. | Stem cells (Dayton, Ohio) 20061201 |
| Dissecting the roles of checkpoint kinase 1/CDC2 and mitogen-activated protein kinase kinase 1/2/extracellular signal-regulated kinase 1/2 in relation to 7-hydroxystaurosporine-induced apoptosis in human multiple myeloma cells. | Molecular pharmacology 20061201 |
| Effect of acrylamide on the cytoskeleton and apoptosis of bovine lens epithelial cells. | Cell biology international 20061201 |
| Intracellular replication of Edwardsiella tarda in murine macrophage is dependent on the type III secretion system and induces an up-regulation of anti-apoptotic NF-kappaB target genes protecting the macrophage from staurosporine-induced apoptosis. | Microbial pathogenesis 20061201 |
| Spironolactone induces apoptosis and inhibits NF-kappaB independent of the mineralocorticoid receptor. | Apoptosis : an international journal on programmed cell death 20061201 |
| Molecular imaging of cell death in vivo by a novel small molecule probe. | Apoptosis : an international journal on programmed cell death 20061201 |
| PC12 cells regulate inducible cyclic AMP (cAMP) element repressor expression to differentially control cAMP response element-dependent transcription in response to nerve growth factor and cAMP. | Journal of neurochemistry 20061201 |
| DNA repair contributes to the drug-resistant phenotype of primary acute myeloid leukaemia cells with FLT3 internal tandem duplications and is reversed by the FLT3 inhibitor PKC412. | Leukemia 20061201 |
| Effects of PKC412, nilotinib, and imatinib against GIST-associated PDGFRA mutants with differential imatinib sensitivity. | Gastroenterology 20061201 |
| Identification of novel keratinocyte differentiation modulating compounds by high-throughput screening. | Journal of biomolecular screening 20061201 |
| HIV-1 Vpr-induced apoptosis is cell cycle dependent and requires Bax but not ANT. | PLoS pathogens 20061201 |
| Modulation of cell cycle progression in human tumors: a pharmacokinetic and tumor molecular pharmacodynamic study of cisplatin plus the Chk1 inhibitor UCN-01 (NSC 638850). | Clinical cancer research : an official journal of the American Association for Cancer Research 20061201 |
| Crystal structures of IRAK-4 kinase in complex with inhibitors: a serine/threonine kinase with tyrosine as a gatekeeper. | Structure (London, England : 1993) 20061201 |
| Topoisomerase II and tubulin inhibitors both induce the formation of apoptotic topoisomerase I cleavage complexes. | Molecular cancer therapeutics 20061201 |
| Fungal invasion of normally non-phagocytic host cells. | PLoS pathogens 20061201 |
| K-Cl cotransport in red blood cells from patients with KCC3 isoform mutants. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20061201 |
| Enrichment of non-synchronized cells in the G1, S and G2 phases of the cell cycle for the study of apoptosis. | Biochemical pharmacology 20061130 |
| Dysfunction of regulatory volume increase is a key component of apoptosis. | FEBS letters 20061127 |
| Polycystin-1 promotes PKCalpha-mediated NF-kappaB activation in kidney cells. | Biochemical and biophysical research communications 20061117 |
| Plasma inhibitory activity (PIA): a pharmacodynamic assay reveals insights into the basis for cytotoxic response to FLT3 inhibitors. | Blood 20061115 |
| The effects of lestaurtinib (CEP701) and PKC412 on primary AML blasts: the induction of cytotoxicity varies with dependence on FLT3 signaling in both FLT3-mutated and wild-type cases. | Blood 20061115 |
| Brain-derived neurotrophic factor regulation of N-methyl-D-aspartate receptor-mediated synaptic currents in suprachiasmatic nucleus neurons. | Journal of neuroscience research 20061115 |
| Tyrosine phosphorylation of p145met mediated by EGFR and Src is required for serum-independent survival of human bladder carcinoma cells. | Journal of cell science 20061115 |
| Inhibition of caspase-mediated apoptosis by peroxynitrite in traumatic brain injury. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20061108 |
| Effects of two multi-step self-etch primer/adhesives on apoptosis in human gingival fibroblasts in vitro. | Journal of biomedical materials research. Part B, Applied biomaterials 20061101 |
| Staurosporin induces neurite outgrowth through ROS generation in HN33 hippocampal cell lines. | Journal of neural transmission (Vienna, Austria : 1996) 20061101 |
| IFN-gamma and TNF-alpha regulate human NHE3 gene expression by modulating the Sp family transcription factors in human intestinal epithelial cell line C2BBe1. | American journal of physiology. Cell physiology 20061101 |
| Shuttling of HDAC5 in H9C2 cells regulates YY1 function through CaMKIV/PKD and PP2A. | American journal of physiology. Cell physiology 20061101 |
| N-Arachidonyl-glycine inhibits the glycine transporter, GLYT2a. | Journal of neurochemistry 20061101 |
| Evidence for the role of nitric oxide in antiapoptotic and genotoxic effect of nicotine on human gingival fibroblasts. | Apoptosis : an international journal on programmed cell death 20061101 |
| 12-o-Tetradecanoylphorbol 13-acetate prevents baicalein-induced apoptosis via activation of protein kinase C and JNKs in human leukemia cells. | Apoptosis : an international journal on programmed cell death 20061101 |
| Direct inhibition of T-cell responses by the Cryptococcus capsular polysaccharide glucuronoxylomannan. | PLoS pathogens 20061101 |
| Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo. | PLoS genetics 20061101 |
| The cytokine/neurotrophin axis in peripheral axon outgrowth. | The European journal of neuroscience 20061101 |
| Beyond imatinib: second generation c-KIT inhibitors for the management of gastrointestinal stromal tumors. | Clinical colorectal cancer 20061101 |
| Guanosine effect on cholesterol efflux and apolipoprotein E expression in astrocytes. | Purinergic signalling 20061101 |
| Benzo(a)pyrene inhibits expression of inducible heat shock protein 70 in vascular endothelial cells. | Toxicology letters 20061025 |
| Impact of 17beta-estradiol on cytokine-mediated apoptotic effects in primary hippocampal and neocortical cell cultures. | Brain research 20061020 |
| Dividing roles of prion protein in staurosporine-mediated apoptosis. | Biochemical and biophysical research communications 20061020 |
| Soluble factors from neuronal cultures induce a specific proliferation and resistance to apoptosis of cognate mouse skeletal muscle precursor cells. | Neuroscience letters 20061016 |
| DNA mismatch repair as an effector for promoting phorbol ester-induced apoptotic DNA damage and cell killing: implications in tumor promotion. | International journal of cancer 20061015 |
| Hsp105 family proteins suppress staurosporine-induced apoptosis by inhibiting the translocation of Bax to mitochondria in HeLa cells. | Experimental cell research 20061015 |
| The Chk1-mediated S-phase checkpoint targets initiation factor Cdc45 via a Cdc25A/Cdk2-independent mechanism. | The Journal of biological chemistry 20061013 |
| Inhibition and down-regulation of gene transcription and guanylyl cyclase activity of NPRA by angiotensin II involving protein kinase C. | Biochemical and biophysical research communications 20061013 |
| Mechanism of isoproterenol-induced RGS2 up-regulation in astrocytes. | Biochemical and biophysical research communications 20061013 |
| The multikinase inhibitor midostaurin (PKC412A) lacks activity in metastatic melanoma: a phase IIA clinical and biologic study. | British journal of cancer 20061009 |
| Interaction of F1L with the BH3 domain of Bak is responsible for inhibiting vaccinia-induced apoptosis. | Cell death and differentiation 20061001 |
| Neural precursor cells possess multiple p53-dependent apoptotic pathways. | Cell death and differentiation 20061001 |
| Overexpression of RGPR-p117 enhances regucalcin gene promoter activity in cloned normal rat kidney proximal tubular epithelial cells: involvement of TTGGC motif. | Journal of cellular biochemistry 20061001 |
| Influence of Pi3-K and PKC activity on 99mTc-(V)-DMSA uptake: correlation with tumour aggressiveness in an in vitro malignant glioblastoma cell line model. | European journal of nuclear medicine and molecular imaging 20061001 |
| EGF-induced inhibition of glucose transport is mediated by PKC and MAPK signal pathways in primary cultured chicken hepatocytes. | American journal of physiology. Gastrointestinal and liver physiology 20061001 |
| Low dose leflunomide activates PI3K/Akt signalling in erythroleukemia cells and reduces apoptosis induced by anticancer agents. | Apoptosis : an international journal on programmed cell death 20061001 |
| Involvement of nuclear factor I-A1 in the regulation of regucalcin gene promoter activity in cloned normal rat kidney proximal tubular epithelial cells. | International journal of molecular medicine 20061001 |
| NF-kappaB and inhibitor of apoptosis proteins are required for apoptosis resistance of epithelial cells persistently infected with Chlamydophila pneumoniae. | Cellular microbiology 20061001 |
| Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. | Nature cell biology 20061001 |
| Translocation of classical PKC and cortical granule exocytosis of human oocyte in germinal vesicle and metaphase II stage. | Acta pharmacologica Sinica 20061001 |
| Restoration of E-cadherin sensitizes human melanoma cells for apoptosis. | Melanoma research 20061001 |
| The differential staurosporine-mediated G1 arrest in normal versus tumor cells is dependent on the retinoblastoma protein. | Cancer research 20061001 |
| CDPKs CPK6 and CPK3 function in ABA regulation of guard cell S-type anion- and Ca(2+)-permeable channels and stomatal closure. | PLoS biology 20061001 |
| The proinflammatory cytokine interleukin-18 alters multiple signaling pathways to inhibit natural killer cell death. | Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20061001 |
| Structure selection for protein kinase docking and virtual screening: homology models or crystal structures? | Current protein & peptide science 20061001 |
| Poly(ADP-ribosyl)ation regulates heat shock factor-1 activity and the heat shock response in murine fibroblasts. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20061001 |
| Apoptosis mediated by p53 in rat neural AF5 cells following treatment with hydrogen peroxide and staurosporine. | Brain research 20060927 |
| GCP60 preferentially interacts with a caspase-generated golgin-160 fragment. | The Journal of biological chemistry 20060922 |
| Desensitization of somatostatin-induced inhibition of low extracellular magnesium concentration-induced calcium spikes in cultured rat hippocampal neurons. | Brain research 20060921 |
| Staurosporine and rebeccamycin aglycones are assembled by the oxidative action of StaP, StaC, and RebC on chromopyrrolic acid. | Journal of the American Chemical Society 20060920 |
| HaCaT keratinocyte migration is dependent on epidermal growth factor receptor signaling and glycogen synthase kinase-3alpha. | Experimental cell research 20060910 |
| Mitogen-activated protein kinases interacting kinases are autoinhibited by a reprogrammed activation segment. | The EMBO journal 20060906 |
| Hypoxia and HIF-1alpha protect A549 cells from drug-induced apoptosis. | Cell death and differentiation 20060901 |
| Inhibitors of the PI3-kinase/Akt pathway induce mitotic catastrophe in non-small cell lung cancer cells. | International journal of cancer 20060901 |
| Effect of methylglyoxal modification and phosphorylation on the chaperone and anti-apoptotic properties of heat shock protein 27. | Journal of cellular biochemistry 20060901 |
| Pharmacological properties of glycine uptake in the developing rat retina. | Neurochemistry international 20060901 |
| Signaling pathways involved with the stimulatory effect of angiotensin II on vacuolar H+-ATPase in proximal tubule cells. | Pflugers Archiv : European journal of physiology 20060901 |
| Apoptotic cells promote macrophage survival by releasing the antiapoptotic mediator sphingosine-1-phosphate. | Blood 20060901 |
| The heat shock protein 90 of Eimeria tenella is essential for invasion of host cell and schizont growth. | International journal for parasitology 20060901 |
| Mutations of phosphorylation sites Ser10 and Thr187 of p27Kip1 abolish cytoplasmic redistribution but do not abrogate G0/1 phase arrest in the HepG2 cell line. | Biochemical and biophysical research communications 20060901 |
| Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation. | Nature chemical biology 20060901 |
| Superoxide stimulates NaCl absorption in the thick ascending limb via activation of protein kinase C. | Hypertension (Dallas, Tex. : 1979) 20060901 |
| Airway hyper-responsiveness in allergic asthma in guinea-pigs is mediated by nerve growth factor via the induction of substance P: a potential role for trkA. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20060901 |
| Activation of the extracellular calcium-sensing receptor initiates insulin secretion from human islets of Langerhans: involvement of protein kinases. | The Journal of endocrinology 20060901 |
| Development and optimization of a non-radioactive JNK3 assay. | Combinatorial chemistry & high throughput screening 20060901 |
| Rapid assessment of early biophysical changes in K562 cells during apoptosis determined using dielectrophoresis. | International journal of nanomedicine 20060901 |
| Involvement of JNK-initiated p53 accumulation and phosphorylation of p53 in pseudolaric acid B induced cell death. | Experimental & molecular medicine 20060831 |
| Group I mGluR regulates the polarity of spike-timing dependent plasticity in substantia gelatinosa neurons. | Biochemical and biophysical research communications 20060825 |
| Storage of spatial information by the maintenance mechanism of LTP. | Science (New York, N.Y.) 20060825 |
| Novel structural features of CDK inhibition revealed by an ab initio computational method combined with dynamic simulations. | Journal of medicinal chemistry 20060824 |
| Role of the Phox homology domain and phosphorylation in activation of serum and glucocorticoid-regulated kinase-3. | The Journal of biological chemistry 20060818 |
| Carbenoxolone inhibits junctional transfer and upregulates Connexin43 expression by a protein kinase A-dependent pathway. | Journal of cellular biochemistry 20060815 |
| The positive inotropic effect of the aqueous extract of Convallaria keiskei in beating rabbit atria. | Life sciences 20060815 |
| In vitro pharmacological actions of sinomenine on the smooth muscle and the endothelial cell activity in rat aorta. | Life sciences 20060815 |
| BDNF enhances dendritic Ca2+ signals evoked by coincident EPSPs and back-propagating action potentials in CA1 pyramidal neurons. | Brain research 20060809 |
| Calcium-independent phospholipase A2 localizes in and protects mitochondria during apoptotic induction by staurosporine. | The Journal of biological chemistry 20060804 |
| Structure of human Fyn kinase domain complexed with staurosporine. | Biochemical and biophysical research communications 20060804 |
| Induction of cytosolic phospholipase A2 by lipopolysaccharide in canine tracheal smooth muscle cells: involvement of MAPKs and NF-kappaB pathways. | Cellular signalling 20060801 |
| Inhibition of the renal betaine transporter by calcium ions. | American journal of physiology. Renal physiology 20060801 |
| Galpha(s) sensitizes human SH-SY5Y cells to apoptosis independently of the protein kinase A pathway. | Journal of neuroscience research 20060801 |
| Agonist-selective mechanisms of mu-opioid receptor desensitization in human embryonic kidney 293 cells. | Molecular pharmacology 20060801 |
| Lectin-like oxidized low-density lipoprotein receptor-1-mediated autophagy in human granulosa cells as an alternative of programmed cell death. | Endocrinology 20060801 |
| Dual effects of staurosporine on A431 and NRK cells: microfilament disassembly and uncoordinated lamellipodial activity followed by cell death. | European journal of cell biology 20060801 |
| Homologous down-regulation of histamine H3 receptors in rat striatal slices. | Synapse (New York, N.Y.) 20060801 |
| Cloning of a novel human caspase-9 splice variant containing only the CARD domain. | Life sciences 20060801 |
| Regulatory effect of exogenous regucalcin on cell function in osteoblastic MC3T3-E1 cells: involvement of intracellular signaling factor. | International journal of molecular medicine 20060801 |
| Roles of insulin-like growth factor II in cardiomyoblast apoptosis and in hypertensive rat heart with abdominal aorta ligation. | American journal of physiology. Endocrinology and metabolism 20060801 |
| Reevaluation of the violacein biosynthetic pathway and its relationship to indolocarbazole biosynthesis. | Chembiochem : a European journal of chemical biology 20060801 |
| Histone deacetylase inhibitors (HDI) cause DNA damage in leukemia cells: a mechanism for leukemia-specific HDI-dependent apoptosis? | Molecular cancer research : MCR 20060801 |
| Brain-derived neurotrophic factor and neurotrophin receptors modulate glutamate-induced phase shifts of the suprachiasmatic nucleus. | The European journal of neuroscience 20060801 |
| Nucleoside diphosphate kinase A as a controller of AMP-kinase in airway epithelia. | Journal of bioenergetics and biomembranes 20060801 |
| JNK- and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells. | The Journal of biological chemistry 20060728 |
| ADAM10-mediated release of complement membrane cofactor protein during apoptosis of epithelial cells. | The Journal of biological chemistry 20060728 |
| Nicotine regulates SH-SY5Y neuroblastoma cell proliferation through the release of brain-derived neurotrophic factor. | Brain research 20060726 |
| Cell death, caspase activation, and HMGB1 release of porcine choroid plexus epithelial cells during Streptococcus suis infection in vitro. | Brain research 20060719 |
| Assays of endogenous caspase activities: a comparison of mass spectrometry and fluorescence formats. | Analytical chemistry 20060715 |
| Enhanced ERK dependent CREB activation reduces apoptosis in staurosporine-treated human neuroblastoma SK-N-BE(2)C cells. | Neuroscience letters 20060710 |
| BH3-only proapoptotic Bcl-2 family members Noxa and Puma mediate neural precursor cell death. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060705 |
| Method validation and preliminary qualification of pharmacodynamic biomarkers employed to evaluate the clinical efficacy of an antisense compound (AEG35156) targeted to the X-linked inhibitor of apoptosis protein XIAP. | British journal of cancer 20060703 |
| Smac/DIABLO is not released from mitochondria during apoptotic signalling in cells deficient in cytochrome c. | Cell death and differentiation 20060701 |
| Protein kinase C-mediated endothelial barrier regulation is caveolin-1-dependent. | Histochemistry and cell biology 20060701 |
| Engineering biosynthetic pathways to generate antitumor indolocarbazole derivatives. | Journal of industrial microbiology & biotechnology 20060701 |
| Effects of hypo-osmotic stress on ATP release in isolated turbot (Scophthalmus maximus) hepatocytes. | Biology of the cell 20060701 |
| Estrogens cross-talk to alpha1b-adrenergic receptors. | Molecular pharmacology 20060701 |
| The first ALS2 missense mutation associated with JPLS reveals new aspects of alsin biological function. | Brain : a journal of neurology 20060701 |
| Dexamethasone inhibits apoptosis in C6 glioma cells through increased expression of Bcl-XL. | Apoptosis : an international journal on programmed cell death 20060701 |
| Increase of Fas-induced apoptosis by inhibition of extracellular phosphorylation of Fas receptor in Jurkat cell line. | Apoptosis : an international journal on programmed cell death 20060701 |
| PINOID positively regulates auxin efflux in Arabidopsis root hair cells and tobacco cells. | The Plant cell 20060701 |
| PAR-1 upregulation by trimethyltin and lipopolysaccharide in cultured rat astrocytes. | International journal of molecular medicine 20060701 |
| Chromatin condensation of ovarian nurse and follicle cells is regulated independently from DNA fragmentation during Drosophila late oogenesis. | Differentiation; research in biological diversity 20060701 |
| Peri-nuclear clustering of mitochondria is triggered during aluminum maltolate induced apoptosis. | Journal of Alzheimer's disease : JAD 20060701 |
| Vanadyl(IV) complexes with saccharides. Bioactivity in osteoblast-like cells in culture. | Canadian journal of physiology and pharmacology 20060701 |
| Relative roles of protein kinase A and protein kinase C in modulation of transient receptor potential vanilloid type 1 receptor responsiveness in rat sensory neurons in vitro and peripheral nociceptors in vivo. | Neuroscience 20060630 |
| Ubiquitous calpains promote both apoptosis and survival signals in response to different cell death stimuli. | The Journal of biological chemistry 20060630 |
| Stat3 cleavage by caspases: impact on full-length Stat3 expression, fragment formation, and transcriptional activity. | The Journal of biological chemistry 20060630 |
| Caspase-dependant activation of chymotrypsin-like proteases mediates nuclear events during Jurkat T cell apoptosis. | Biochemical and biophysical research communications 20060630 |
| Phosphoryl transfer is not rate-limiting for the ROCK I-catalyzed kinase reaction. | Biochemistry 20060627 |
| Chronic UVA irradiation of human HaCaT keratinocytes induces malignant transformation associated with acquired apoptotic resistance. | Oncogene 20060622 |
| Reversal of endothelial nitric oxide synthase uncoupling and up-regulation of endothelial nitric oxide synthase expression lowers blood pressure in hypertensive rats. | Journal of the American College of Cardiology 20060620 |
| Coxsackievirus protein 2BC blocks host cell apoptosis by inhibiting caspase-3. | The Journal of biological chemistry 20060616 |
| Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin. | Cell 20060616 |
| Targeting the c-Met signaling pathway in cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060615 |
| HMGB1, a novel cytokine-like mediator linking acute neuronal death and delayed neuroinflammation in the postischemic brain. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060614 |
| Dermcidin expression in hepatic cells improves survival without N-glycosylation, but requires asparagine residues. | British journal of cancer 20060605 |
| Effects of protein kinase inhibitors on the in vitro growth of Babesia bovis. | Parasitology 20060601 |
| Differences in the biophysical properties of membrane and cytoplasm of apoptotic cells revealed using dielectrophoresis. | Biochimica et biophysica acta 20060601 |
| Extracellular signal regulated MAP-kinase signalling in osmotically stressed trout hepatocytes. | Biochimica et biophysica acta 20060601 |
| Method for monitoring of mitochondrial cytochrome c release during cell death: Immunodetection of cytochrome c by flow cytometry after selective permeabilization of the plasma membrane. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060601 |
| Oxidative stress induces actin-cytoskeletal and tight-junctional alterations in hepatocytes by a Ca2+ -dependent, PKC-mediated mechanism: protective effect of PKA. | Free radical biology & medicine 20060601 |
| A priori inference of cross reactivity for drug-targeted kinases. | Journal of medicinal chemistry 20060601 |
| Crystal structure of the MAP3K TAO2 kinase domain bound by an inhibitor staurosporine. | Acta biochimica et biophysica Sinica 20060601 |
| Silencing the constitutive active transcription factor CREB by the LKB1-SIK signaling cascade. | The FEBS journal 20060601 |
| Cross-inhibitory interactions between GABAA and P2X channels in myenteric neurones. | The European journal of neuroscience 20060601 |
| N-carboxamido-staurosporine and selina-4(14),7(11)-diene-8,9-diol, new metabolites from a marine Streptomyces sp. | The Journal of antibiotics 20060601 |
| Telomerase confers resistance to caspase-mediated apoptosis. | Clinical interventions in aging 20060601 |
| Synergism between staurosporine and drugs inducing endoplasmic reticulum stress. | Biochemical pharmacology 20060528 |
| Amyloid precursor protein is involved in staurosporine induced glial differentiation of neural progenitor cells. | Biochemical and biophysical research communications 20060526 |
| Potentiation of the anticancer effect of valproic acid, an antiepileptic agent with histone deacetylase inhibitory activity, by the kinase inhibitor Staurosporine or its clinically relevant analogue UCN-01. | British journal of cancer 20060522 |
| Posttranslational N-myristoylation is required for the anti-apoptotic activity of human tGelsolin, the C-terminal caspase cleavage product of human gelsolin. | The Journal of biological chemistry 20060519 |
| Ser-2030, but not Ser-2808, is the major phosphorylation site in cardiac ryanodine receptors responding to protein kinase A activation upon beta-adrenergic stimulation in normal and failing hearts. | The Biochemical journal 20060515 |
| The increase in mitochondrial association with actin precedes Bax translocation in apoptosis. | The Biochemical journal 20060515 |
| Effect of construct design on MAPKAP kinase-2 activity, thermodynamic stability and ligand-binding affinity. | Archives of biochemistry and biophysics 20060515 |
| Cardiac ryanodine receptor phosphorylation: target sites and functional consequences. | The Biochemical journal 20060515 |
| Peroxisome proliferator-activated receptor alpha activation decreases metastatic potential of melanoma cells in vitro via down-regulation of Akt. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060515 |
| p21CDKN1A allows the repair of replication-mediated DNA double-strand breaks induced by topoisomerase I and is inactivated by the checkpoint kinase inhibitor 7-hydroxystaurosporine. | Oncogene 20060511 |
| DNA-PK phosphorylates histone H2AX during apoptotic DNA fragmentation in mammalian cells. | DNA repair 20060510 |
| Capacitation-like changes in equine spermatozoa following cryopreservation. | Theriogenology 20060501 |
| Efficient execution of cell death in non-glycolytic cells requires the generation of ROS controlled by the activity of mitochondrial H+-ATP synthase. | Carcinogenesis 20060501 |
| Point mutations in the juxtamembrane domain of FLT3 define a new class of activating mutations in AML. | Blood 20060501 |
| meso-Dihydroguaiaretic acid attenuates the neurotoxic effect of staurosporine in primary rat cortical cultures. | Neuropharmacology 20060501 |
| Identification of various allosteric interaction sites on M1 muscarinic receptor using 125I-Met35-oxidized muscarinic toxin 7. | Molecular pharmacology 20060501 |
| Proteolytic activation of latent TGF-beta precedes caspase-3 activation and enhances apoptotic death of lung epithelial cells. | Journal of cellular physiology 20060501 |
| Oxidative stress induces internalization of the bile salt export pump, Bsep, and bile salt secretory failure in isolated rat hepatocyte couplets: a role for protein kinase C and prevention by protein kinase A. | Toxicological sciences : an official journal of the Society of Toxicology 20060501 |
| Parathyroid hormone increases beta-catenin levels through Smad3 in mouse osteoblastic cells. | Endocrinology 20060501 |
| Modulation of p53 transcriptional activity by PRIMA-1 and Pifithrin-alpha on staurosporine-induced apoptosis of wild-type and mutated p53 epithelial cells. | Apoptosis : an international journal on programmed cell death 20060501 |
| RebG- and RebM-catalyzed indolocarbazole diversification. | Chembiochem : a European journal of chemical biology 20060501 |
| Enhancement of substrate-gated Cl- currents via rat glutamate transporter EAAT4 by PMA. | American journal of physiology. Cell physiology 20060501 |
| PGE(2) receptors and their intracellular mechanisms in rabbit small intestine. | Prostaglandins & other lipid mediators 20060501 |
| Equol and para-ethyl-phenol stimulate prostaglandin F(2alpha) secretion in bovine corpus luteum: intracellular mechanisms of action. | Prostaglandins & other lipid mediators 20060501 |
| Recruitment of BAD by the Chlamydia trachomatis vacuole correlates with host-cell survival. | PLoS pathogens 20060501 |
| Staurosporine-induced growth inhibition of glioma cells is accompanied by altered expression of cyclins, CDKs and CDK inhibitors. | Neurochemical research 20060501 |
| Caspase-3-derived C-terminal product of synphilin-1 displays antiapoptotic function via modulation of the p53-dependent cell death pathway. | The Journal of biological chemistry 20060428 |
| Isolation and antifungal and antioomycete activities of staurosporine from Streptomyces roseoflavus strain LS-A24. | Journal of agricultural and food chemistry 20060419 |
| Bcl-2 overexpression prevents calcium overload and subsequent apoptosis in dystrophic myotubes. | The Biochemical journal 20060415 |
| Metallothionein isoform 2A expression is inducible and protects against ROS-mediated cell death in rotenone-treated HeLa cells. | The Biochemical journal 20060415 |
| Retinoic acid induces p27Kip1 nuclear accumulation by modulating its phosphorylation. | Cancer research 20060415 |
| Relative timing of redistribution of cytochrome c and Smac/DIABLO from mitochondria during apoptosis assessed by double immunocytochemistry on mammalian cells. | Experimental cell research 20060415 |
| Mechanisms of nitric-oxide-induced increase of free cytosolic Ca2+ concentration in Nicotiana plumbaginifolia cells. | Free radical biology & medicine 20060415 |
| The mitochondrial effects of small organic ligands of BCL-2: sensitization of BCL-2-overexpressing cells to apoptosis by a pyrimidine-2,4,6-trione derivative. | The Journal of biological chemistry 20060414 |
| Spike timing-dependent LTP/LTD mediates visual experience-dependent plasticity in a developing retinotectal system. | Neuron 20060406 |
| K252a, an inhibitor of Trk, disturbs pathfinding of hippocampal mossy fibers. | Neuroreport 20060403 |
| Effect of staurosporine-induced apoptosis on endothelial nitric oxide synthase in transfected COS-7 cells and primary endothelial cells. | Cell death and differentiation 20060401 |
| Identification and characterization of a constitutively T-loop phosphorylated and active recombinant S6K1: expression, purification, and enzymatic studies in a high capacity non-radioactive TR-FRET Lance assay. | Protein expression and purification 20060401 |
| Relationship between SUMO-1 modification of caspase-7 and its nuclear localization in human neuronal cells. | Neuroscience letters 20060401 |
| Brain-derived neurotrophic factor silences GABA synapses onto hypothalamic neuroendocrine cells through a postsynaptic dynamin-mediated mechanism. | Journal of neurophysiology 20060401 |
| mtDNA controls expression of the Death Associated Protein 3. | Experimental cell research 20060401 |
| Synthesis and structure-activity relationship of 3,4'-bispyridinylethylenes: discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer. | Bioorganic & medicinal chemistry letters 20060401 |
| Aminoglutethimide prevents excitotoxic and ischemic injuries in cortical neurons. | British journal of pharmacology 20060401 |
| Screening for caspase-3 inhibitors: a new class of potent small-molecule inhibitors of caspase-3. | Journal of biomolecular screening 20060401 |
| Rapamycin pre-treatment protects against apoptosis. | Human molecular genetics 20060401 |
| Caspase cleaved presenilin-1 is part of active gamma-secretase complexes. | Journal of neurochemistry 20060401 |
| On the observed large interspecies overprediction of human clearance ('vertical allometry') of UCN-01: further support for a proposed model based on plasma protein binding. | Journal of clinical pharmacology 20060401 |
| Heparin prevents programmed cell death in human trophoblast. | Molecular human reproduction 20060401 |
| Chk1 requirement for high global rates of replication fork progression during normal vertebrate S phase. | Molecular and cellular biology 20060401 |
| Targeted ablation of Par-4 reveals a cell type-specific susceptibility to apoptosis-inducing agents. | Cancer research 20060401 |
| Multiparameter measurement of caspase 3 activation and apoptotic cell death in NT2 neuronal precursor cells using high-content analysis. | Journal of biomolecular screening 20060401 |
| [The present status of, and problems with the development of FLT3 kinase inhibitors]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20060401 |
| Cell type-specific resistance of trigeminal ganglion neurons towards apoptotic stimuli. | Veterinary microbiology 20060331 |
| PS exposure increases the susceptibility of cells to fusion with DOTAP liposomes. | Chemico-biological interactions 20060325 |
| NMR analysis of a Tau phosphorylation pattern. | Journal of the American Chemical Society 20060322 |
| Slowing of the inactivation of voltage-dependent sodium channels by staurosporine, the protein kinase C inhibitor, in rabbit atrial myocytes. | European journal of pharmacology 20060318 |
| Prostate-derived sterile 20-like kinase 2 (PSK2) regulates apoptotic morphology via C-Jun N-terminal kinase and Rho kinase-1. | The Journal of biological chemistry 20060317 |
| Bergmann glia utilize active caspase-3 for differentiation. | Brain research 20060317 |
| Pharmacodynamics of cytarabine alone and in combination with 7-hydroxystaurosporine (UCN-01) in AML blasts in vitro and during a clinical trial. | Blood 20060315 |
| Discovery of trans-3,4'-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation. | Bioorganic & medicinal chemistry letters 20060315 |
| Antiapoptotic effects of erythropoietin in differentiated neuroblastoma SH-SY5Y cells require activation of both the STAT5 and AKT signaling pathways. | The Journal of biological chemistry 20060303 |
| Phosphorylation site mutated RB exerts contrasting effects on apoptotic response to different stimuli. | Oncogene 20060302 |
| Regulation of homocysteine-induced MMP-9 by ERK1/2 pathway. | American journal of physiology. Cell physiology 20060301 |
| Drug-induced apoptosis was markedly attenuated in endometriotic stromal cells. | Human reproduction (Oxford, England) 20060301 |
| ApoSense: a novel technology for functional molecular imaging of cell death in models of acute renal tubular necrosis. | European journal of nuclear medicine and molecular imaging 20060301 |
| Tumor suppressive maspin and epithelial homeostasis. | Journal of cellular biochemistry 20060301 |
| Clustering transmembrane-agrin induces filopodia-like processes on axons and dendrites. | Molecular and cellular neurosciences 20060301 |
| Sphingosine 1-phosphate is released from the cytosol of rat platelets in a carrier-mediated manner. | Journal of lipid research 20060301 |
| Induction of BAALC and down regulation of RAMP3 in astrocytes treated with differentiation inducers. | Cell biology international 20060301 |
| Signal transduction events involved in human epithelial cell invasion by Campylobacter jejuni 81-176. | Microbial pathogenesis 20060301 |
| Novel apoptosis assay to analyze immunosuppression. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060301 |
| High glucose-induced inhibition of 2-deoxyglucose uptake is mediated by cAMP, protein kinase C, oxidative stress and mitogen-activated protein kinases in mouse embryonic stem cells. | Clinical and experimental pharmacology & physiology 20060301 |
| Effects of protein kinase and phosphatidylinositol-3 kinase inhibitors on growth and ultrastructure of Trypanosoma cruzi. | FEMS microbiology letters 20060301 |
| Emerging Flt3 kinase inhibitors in the treatment of leukaemia. | Expert opinion on emerging drugs 20060301 |
| Suppressive effect of elongation factor 2 on apoptosis induced by HIV-1 viral protein R. | Apoptosis : an international journal on programmed cell death 20060301 |
| Role of Src-specific phosphorylation site on focal adhesion kinase for senescence-associated apoptosis resistance. | Apoptosis : an international journal on programmed cell death 20060301 |
| Brazilian green propolis protects against retinal damage in vitro and in vivo. | Evidence-based complementary and alternative medicine : eCAM 20060301 |
| Histamine increases sphingosine kinase-1 expression and activity in the human arterial endothelial cell line EA.hy 926 by a PKC-alpha-dependent mechanism. | Biochimica et biophysica acta 20060301 |
| Inhibition of apoptosis by p26: implications for small heat shock protein function during Artemia development. | Cell stress & chaperones 20060301 |
| Selectivity and potency of cyclin-dependent kinase inhibitors. | The AAPS journal 20060301 |
| Apoptosis in Leishmania species & its relevance to disease pathogenesis. | The Indian journal of medical research 20060301 |
| Vascular endothelial growth factor-D is a survival factor for human breast carcinoma cells. | International journal of cancer 20060215 |
| Involvement of the ubiquitin pathway in decreasing Ku70 levels in response to drug-induced apoptosis. | Experimental cell research 20060215 |
| Effects of intravenous anesthetics on the activity of glutamate transporter EAAT3 expressed in Xenopus oocytes: evidence for protein kinase C involvement. | European journal of pharmacology 20060215 |
| Identification of small molecules that sensitize resistant tumor cells to tumor necrosis factor-family death receptors. | Cancer research 20060215 |
| Neuroendocrine protein 7B2 can be inactivated by phosphorylation within the secretory pathway. | The Journal of biological chemistry 20060210 |
| Akt kinase phosphorylation of inositol 1,4,5-trisphosphate receptors. | The Journal of biological chemistry 20060210 |
| Oxidative stress protection by newly synthesized nitrogen compounds with pharmacological potential. | Life sciences 20060209 |
| Establishment of an apoptosis-sensitive rat mammary carcinoma cell line with a mutation in the DNA-binding region of p53. | Cancer letters 20060208 |
| Alteration of protein kinase C conformation in red blood cells: a potential marker for Alzheimer's disease but not for Parkinson's disease. | Neurobiology of aging 20060201 |
| Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic rats. | American journal of physiology. Lung cellular and molecular physiology 20060201 |
| Establishment of primary cultures of rat olfactory bulb under serum-free conditions for studies of cellular injury. | Cell and tissue research 20060201 |
| Changes in tight junctional resistance of the cervical epithelium are associated with modulation of content and phosphorylation of occludin 65-kilodalton and 50-kilodalton forms. | Endocrinology 20060201 |
| Phase I trial of UCN-01 in combination with topotecan in patients with advanced solid cancers: a Princess Margaret Hospital Phase II Consortium study. | Annals of oncology : official journal of the European Society for Medical Oncology 20060201 |
| Nerve growth factor regulates substance P in adult sensory neurons through both TrkA and p75 receptors. | Experimental neurology 20060201 |
| Microarrays for the functional analysis of the chemical-kinase interactome. | Journal of biomolecular screening 20060201 |
| Presynaptic effects of anandamide and WIN55,212-2 on glutamatergic nerve endings isolated from rat hippocampus. | Neurochemistry international 20060201 |
| Analyzing a kinetic titration series using affinity biosensors. | Analytical biochemistry 20060201 |
| Interleukin-1 stimulates beta-cell necrosis and release of the immunological adjuvant HMGB1. | PLoS medicine 20060201 |
| Distinct effects of p75 in mediating actions of neurotrophins on basal forebrain oligodendrocytes. | Molecular and cellular neurosciences 20060201 |
| Wild-type huntingtin protects neurons from excitotoxicity. | Journal of neurochemistry 20060201 |
| Assessment of neuroprotective effects of glutamate modulation on glaucoma-related retinal ganglion cell apoptosis in vivo. | Investigative ophthalmology & visual science 20060201 |
| Effect of erythropoietin on staurosporine-induced apoptosis and differentiation of SH-SY5Y neuroblastoma cells. | Biochimica et biophysica acta 20060201 |
| PTEN: a crucial mediator of mitochondria-dependent apoptosis. | Apoptosis : an international journal on programmed cell death 20060201 |
| Staurosporine modulates radiosensitivity and radiation-induced apoptosis in U937 cells. | International journal of radiation biology 20060201 |
| Phosphorylation of the alpha 2(1) procollagen promoter binding proteins is required for promoter activity. | IUBMB life 20060201 |
| Highly potent and specific GSK-3beta inhibitors that block tau phosphorylation and decrease alpha-synuclein protein expression in a cellular model of Parkinson's disease. | ChemMedChem 20060201 |
| Apoptotic effect of ethanol is potentiated by caffeine-induced calcium release in rat astrocytes. | Neuroscience letters 20060130 |
| Rapid access to unexplored chemical space by ligand scanning around a ruthenium center: discovery of potent and selective protein kinase inhibitors. | Journal of the American Chemical Society 20060125 |
| Memantine attenuates staurosporine-induced activation of caspase-3 and LDH release in mouse primary neuronal cultures. | Brain research 20060119 |
| Characterization of anti-apoptotic action of TCDD as a defensive cellular stress response reaction against the cell damaging action of ultra-violet irradiation in an immortalized normal human mammary epithelial cell line, MCF10A. | Toxicology 20060116 |
| PKC412 inhibits in vitro growth of neoplastic human mast cells expressing the D816V-mutated variant of KIT: comparison with AMN107, imatinib, and cladribine (2CdA) and evaluation of cooperative drug effects. | Blood 20060115 |
| Angiotensin II induces the expression of tissue factor and its mechanism in human monocytes. | Thrombosis research 20060101 |
| Polyamine depletion inhibits apoptosis following blocking of survival pathways in human chondrocytes stimulated by tumor necrosis factor-alpha. | Journal of cellular physiology 20060101 |
| Regulation of potassium transport in human lens epithelial cells. | Experimental eye research 20060101 |
| EGF stimulates proliferation of mouse embryonic stem cells: involvement of Ca2+ influx and p44/42 MAPKs. | American journal of physiology. Cell physiology 20060101 |
| Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain. | Blood 20060101 |
| Role of protein kinases in mediating diabetes-induced augmented vasoconstriction to endothelin-1 in the renal arteries of STZ-diabetic rats. | Cell biochemistry and function 20060101 |
| Regulation of cardiac inwardly rectifying potassium current IK1 and Kir2.x channels by endothelin-1. | Journal of molecular medicine (Berlin, Germany) 20060101 |
| Synthesis and biological activity of N,N-dialkylaminoalkyl-substituted bisindolyl and diphenyl pyrazolone derivatives. | Bioorganic & medicinal chemistry 20060101 |
| Characterization of a serine protease-mediated cell death program activated in human leukemia cells. | Experimental cell research 20060101 |
| The involvement of protein kinases in signalling of opioid agonist FK 33-824 in porcine granulosa cells. | Animal reproduction science 20060101 |
| Antitumor triptycene analogs induce a rapid collapse of mitochondrial transmembrane potential in HL-60 cells and isolated mitochondria. | International journal of oncology 20060101 |
| Polyphenol amentoflavone affords neuroprotection against neonatal hypoxic-ischemic brain damage via multiple mechanisms. | Journal of neurochemistry 20060101 |
| Protein kinase C mediates erythrocyte 'programmed cell death' following glucose depletion. | American journal of physiology. Cell physiology 20060101 |
| Aspergillus fumigatus conidia inhibit tumour necrosis factor- or staurosporine-induced apoptosis in epithelial cells. | International immunology 20060101 |
| Kinase-dependent differentiation of a retinal ganglion cell precursor. | Investigative ophthalmology & visual science 20060101 |
| The inhibitory effect of phenylpropanoid glycosides and iridoid glucosides on free radical production and beta2 integrin expression in human leucocytes. | The Journal of pharmacy and pharmacology 20060101 |
| In vitro immune toxicity of depleted uranium: effects on murine macrophages, CD4+ T cells, and gene expression profiles. | Environmental health perspectives 20060101 |
| Caspase-like activity is essential for long-term synaptic plasticity in the terrestrial snail Helix. | The European journal of neuroscience 20060101 |
| Cytosolic labile zinc: a marker for apoptosis in the developing rat brain. | The European journal of neuroscience 20060101 |
| The tumor suppressor DAL-1/4.1B and protein methylation cooperate in inducing apoptosis in MCF-7 breast cancer cells. | Molecular cancer 20060101 |
| Activation of nitric oxide modulator effect by isometric contraction in rat resistance arteries. | Journal of cardiovascular pharmacology 20060101 |
| Up-regulation of alpha1A-adrenoceptors in rat mesenteric artery involves intracellular signal pathways. | Basic & clinical pharmacology & toxicology 20060101 |
| Development of a fluorescence peptide chip for the detection of caspase activity. | Combinatorial chemistry & high throughput screening 20060101 |
| Hydrogen peroxide produced inside mitochondria takes part in cell-to-cell transmission of apoptotic signal. | Biochemistry. Biokhimiia 20060101 |
| Signaling for contraction and relaxation in smooth muscle of the gut. | Annual review of physiology 20060101 |
| Temporal activation of anti- and pro-apoptotic factors in human gingival fibroblasts infected with the periodontal pathogen, Porphyromonas gingivalis: potential role of bacterial proteases in host signalling. | BMC microbiology 20060101 |
| DOCA-induced phosphorylation of glycogen synthase kinase 3beta. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20060101 |
| PKC and MAPKs pathways mediate EGF-induced stimulation of 2-deoxyglucose uptake in mouse embryonic stem cells. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20060101 |
| Interferon-gamma increases neuronal death in response to amyloid-beta1-42. | Journal of neuroinflammation 20060101 |
| In vitro and in vivo effects of the PPAR-alpha agonists fenofibrate and retinoic acid in endometrial cancer. | Molecular cancer 20060101 |
| Cancer and kinases: reports from the front line. | Genome biology 20060101 |
| Volume-sensitive chloride channels involved in apoptotic volume decrease and cell death. | The Journal of membrane biology 20060101 |
| Expression, purification, and characterization of an enzymatically active truncated human rho-kinase I (ROCK I) domain expressed in Sf-9 insect cells. | Protein and peptide letters 20060101 |
| Bax inhibitor-1 protects neurons from oxygen-glucose deprivation. | Journal of molecular neuroscience : MN 20060101 |
| Presenilin 1 forms aggresomal deposits in response to heat shock. | Journal of molecular neuroscience : MN 20060101 |
| HOXA11 mutation in amegakaryocytic thrombocytopenia with radio-ulnar synostosis syndrome inhibits megakaryocytic differentiation in vitro. | Blood cells, molecules & diseases 20060101 |
| Identification and characterisation of human apoptosis inducing proteins using cell-based transfection microarrays and expression analysis. | BMC genomics 20060101 |
| Glutamate-induced apoptosis in neuronal cells is mediated via caspase-dependent and independent mechanisms involving calpain and caspase-3 proteases as well as apoptosis inducing factor (AIF) and this process is inhibited by equine estrogens. | BMC neuroscience 20060101 |
| Protein phosphorylation and membrane association of sucrose synthase in developing tomato fruit. | Plant physiology and biochemistry : PPB 20060101 |
| Neuroprotective activity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (PAN-811), a cancer therapeutic agent. | CNS drug reviews 20060101 |
| Intracameral toxicity of bacterial components muramyl dipeptide and staurosporine: ciliary cyst formation, epithelial cell apoptosis and necrosis. | Cutaneous and ocular toxicology 20060101 |
| Cyclic-AMP response element-based signaling assays for characterization of Trk family tyrosine kinases modulators. | Neuro-Signals 20060101 |
| Comprehensive quality control utilizing the prehybridization third-dye image leads to accurate gene expression measurements by cDNA microarrays. | BMC bioinformatics 20060101 |
| [Apoptosis of host cells regulation by Chlamydia]. | Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20060101 |
| Heparin (GAG-hed) inhibits LCR activity of human papillomavirus type 18 by decreasing AP1 binding. | BMC cancer 20060101 |
| Gene expression analysis in HBV transgenic mouse liver: a model to study early events related to hepatocarcinogenesis. | Molecular medicine (Cambridge, Mass.) 20060101 |
| Identification of genes associated with cisplatin resistance in human oral squamous cell carcinoma cell line. | BMC cancer 20060101 |
| Correlated fragile site expression allows the identification of candidate fragile genes involved in immunity and associated with carcinogenesis. | BMC bioinformatics 20060101 |
| Molecular pathways leading to oxidative stress-induced phosphorylation of Akt. | Antioxidants & redox signaling 20060101 |
| Microarray-based identification and RT-PCR test screening for epithelial-specific mRNAs in peripheral blood of patients with colon cancer. | BMC cancer 20060101 |
| Expression of the bile acid receptor FXR in Barrett's esophagus and enhancement of apoptosis by guggulsterone in vitro. | Molecular cancer 20060101 |
| Tiam1 regulates cell adhesion, migration and apoptosis in colon tumor cells. | Clinical & experimental metastasis 20060101 |
| Development and implementation of three mitogen-activated protein kinase (MAPK) signaling pathway imaging assays to provide MAPK module selectivity profiling for kinase inhibitors: MK2-EGFP translocation, c-Jun, and ERK activation. | Methods in enzymology 20060101 |
| Differential actin isoform reorganization in the contracting A7r5 cell. | Canadian journal of physiology and pharmacology 20060101 |
| Antitumor and normal cell protective effect of PKC412 in the athymic mouse model of ovarian cancer. | Annals of clinical and laboratory science 20060101 |
| [Proapoptotic action of alpha-tocopheryl succinate in rat thymocytes is conditioned by the inhibition of mitochondrial succinate dehydrogenase]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20060101 |
| Accounting for global protein deformability during protein-protein and protein-ligand docking. | Biochimica et biophysica acta 20051230 |
| WOX1 is essential for tumor necrosis factor-, UV light-, staurosporine-, and p53-mediated cell death, and its tyrosine 33-phosphorylated form binds and stabilizes serine 46-phosphorylated p53. | The Journal of biological chemistry 20051230 |
| Identification of multiple allosteric sites on the M1 muscarinic acetylcholine receptor. | FEBS letters 20051219 |
| FGFR3 as a therapeutic target of the small molecule inhibitor PKC412 in hematopoietic malignancies. | Oncogene 20051215 |
| Integrin-linked kinase is responsible for Ca2+-independent myosin diphosphorylation and contraction of vascular smooth muscle. | The Biochemical journal 20051215 |
| mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes. | The Journal of biological chemistry 20051209 |
| Non-lethal active caspase-3 expression in Bergmann glia of postnatal rat cerebellum. | Brain research. Developmental brain research 20051207 |
| Enzymatic generation of the chromopyrrolic acid scaffold of rebeccamycin by the tandem action of RebO and RebD. | Biochemistry 20051206 |
| Enhanced growth in NS0 cells expressing aminoglycoside phosphotransferase is associated with changes in metabolism, productivity, and apoptosis. | Biotechnology and bioengineering 20051205 |
| Sphingomyelins suppress the targeted disruption of lysosomes/endosomes by the photosensitizer NPe6 during photodynamic therapy. | The Biochemical journal 20051201 |
| Progesterone primes zona pellucida-induced activation of phospholipase A2 during acrosomal exocytosis in guinea pig spermatozoa. | Journal of cellular physiology 20051201 |
| Improved purification of native meningococcal porin PorB and studies on its structure/function. | Protein expression and purification 20051201 |
| Nerve growth factor-induced migration of endothelial cells. | The Journal of pharmacology and experimental therapeutics 20051201 |
| Inhibitory effect of ganglioside GD1b on K+ current in hippocampal neurons and its involvement in apoptosis suppression. | Journal of lipid research 20051201 |
| Biphasic behavior of changes in elemental composition during staurosporine-induced apoptosis. | Apoptosis : an international journal on programmed cell death 20051201 |
| Stathmin prevents the transition from a normal to an endomitotic cell cycle during megakaryocytic differentiation. | Cell cycle (Georgetown, Tex.) 20051201 |
| Evidence that insulin-like growth factor-1 requires protein kinase C-epsilon, PI3-kinase and mitogen-activated protein kinase pathways to protect human vascular smooth muscle cells from apoptosis. | Immunology and cell biology 20051201 |
| Overexpression of RGPR-p117 enhances regucalcin gene expression in cloned normal rat kidney proximal tubular epithelial cells. | International journal of molecular medicine 20051201 |
| Structural basis of inhibitor specificity of the human protooncogene proviral insertion site in moloney murine leukemia virus (PIM-1) kinase. | Journal of medicinal chemistry 20051201 |
| Effect of progesterone on the expression of bax and bcl-2 and on caspase activity in bovine luteal cells. | Prostaglandins & other lipid mediators 20051201 |
| The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases. | PLoS genetics 20051201 |
| Biosynthesis of indocarbazostatin B, incorporation of D-[U-13C] glucose and L-[2-13C] tryptophan. | The Journal of antibiotics 20051201 |
| Cell cycle regulation of astrocytes by extracellular nucleotides and fibroblast growth factor-2. | Purinergic signalling 20051201 |
| FLT3 internal tandem duplication mutations induce myeloproliferative or lymphoid disease in a transgenic mouse model. | Oncogene 20051124 |
| Okadaic acid increases the phosphorylation state of alpha1A-adrenoceptors and induces receptor desensitization. | European journal of pharmacology 20051121 |
| The effect of PKC activity on the TTX-R sodium currents from rat nodose ganglion neurons. | Life sciences 20051119 |
| Chronic treatment with amyloid beta(1-42) inhibits non-cholinergic high-affinity choline transport in NG108-15 cells through protein kinase C signaling. | Brain research 20051116 |
| Caspase-3 is required in the apoptotic disintegration of the nuclear matrix. | Experimental cell research 20051115 |
| Oocytes prevent cumulus cell apoptosis by maintaining a morphogenic paracrine gradient of bone morphogenetic proteins. | Journal of cell science 20051115 |
| Effect of NMDA on staurosporine-induced activation of caspase-3 and LDH release in mouse neocortical and hippocampal cells. | Brain research. Developmental brain research 20051107 |
| Cells die with increased cytosolic ATP during apoptosis: a bioluminescence study with intracellular luciferase. | Cell death and differentiation 20051101 |
| Enhanced JNK activation by NESK without kinase activity upon caspase-mediated cleavage during apoptosis. | Cellular signalling 20051101 |
| Functional intrinsic and extrinsic apoptotic pathways in human fetal mesenchymal stem cells. | Cell death and differentiation 20051101 |
| Ca2+-dependent reduction of IK1 in rat ventricular cells: a novel paradigm for arrhythmia in heart failure? | Cardiovascular research 20051101 |
| Transcription factor specificity protein 1 (Sp1) is the main regulator of nerve growth factor-induced sphingosine kinase 1 gene expression of the rat pheochromocytoma cell line, PC12. | Journal of neurochemistry 20051101 |
| Role of protein kinase C in expression of granulocyte-colony stimulating factor and granulocyte macrophage-colony stimulating factor in lung cancer cells. | International journal of molecular medicine 20051101 |
| Tumour necrosis factor-induced death of adult human oligodendrocytes is mediated by apoptosis inducing factor. | Brain : a journal of neurology 20051101 |
| Endothelin-1 inhibits inward rectifier K+ channels in rabbit coronary arterial smooth muscle cells through protein kinase C. | Journal of cardiovascular pharmacology 20051101 |
| MPS-1 is a K+ channel beta-subunit and a serine/threonine kinase. | Nature neuroscience 20051101 |
| Effect of protein kinase C alpha, caspase-3, and survivin on apoptosis of oral cancer cells induced by staurosporine. | Acta pharmacologica Sinica 20051101 |
| Regulation of the wild-type and Y1235D mutant Met kinase activation. | Biochemistry 20051101 |
| Protein and lipid motifs regulate phosphatidylserine traffic in yeast. | Biochemical Society transactions 20051101 |
| Agents targeting c-Jun N-terminal kinase pathway as potential neuroprotectants. | Expert opinion on investigational drugs 20051101 |
| A photoactivable probe for calcium binding proteins. | Chemistry & biology 20051101 |
| Transient exposure of mammary tumors to PD184352 and UCN-01 causes tumor cell death in vivo and prolonged suppression of tumor regrowth. | Cancer biology & therapy 20051101 |
| Two targets are better than one. Promising combination therapy to treat breast cancer. | Cancer biology & therapy 20051101 |
| Effects of chronic exposure to ethanol on glutamate transporter EAAT3 expressed in Xenopus oocytes: evidence for protein kinase C involvement. | Alcoholism, clinical and experimental research 20051101 |
| Enhanced ROS-generation in lymphocytes from Alzheimer's patients. | Pharmacopsychiatry 20051101 |
| Expression and transcriptional regulation of the GnRH receptor gene in human neuronal cells. | Molecular human reproduction 20051101 |
| [Effect of protein kinase C on human melanoma A375-S2 cell death induced by evodiamine]. | Yao xue xue bao = Acta pharmaceutica Sinica 20051101 |
| NAPOR-3 RNA binding protein is required for apoptosis in hippocampus. | Brain research. Molecular brain research 20051031 |
| Methyltransferase inhibition induces p53-dependent apoptosis and a novel form of cell death. | Oncogene 20051027 |
| The contribution of apoptosis-inducing factor, caspase-activated DNase, and inhibitor of caspase-activated DNase to the nuclear phenotype and DNA degradation during apoptosis. | The Journal of biological chemistry 20051021 |
| Differential responses of Mcl-1 in photosensitized epithelial vs lymphoid-derived human cancer cells. | Oncogene 20051020 |
| Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation. | Blood 20051015 |
| Expression and modulation of an NADPH oxidase in mammalian astrocytes. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20051005 |
| Clematis mandshurica protected to apoptosis of rat chondrocytes. | Journal of ethnopharmacology 20051003 |
| Effect of adenosine triphosphate on phosphate uptake in renal proximal tubule cells: involvement of PKC and p38 MAPK. | Journal of cellular physiology 20051001 |
| Monocyte viability on titanium and copper coated titanium. | Biomaterials 20051001 |
| Membrane association of nitric oxide-sensitive guanylyl cyclase in cardiomyocytes. | Cardiovascular research 20051001 |
| Targeting FLT3 in primary MLL-gene-rearranged infant acute lymphoblastic leukemia. | Blood 20051001 |
| Potentiation of P2X1 ATP-gated currents by 5-hydroxytryptamine 2A receptors involves diacylglycerol-dependent kinases and intracellular calcium. | The Journal of pharmacology and experimental therapeutics 20051001 |
| Early placental insulin-like protein (INSL4 or EPIL) in placental and fetal membrane growth. | Biology of reproduction 20051001 |
| Nitric oxide donors induce neurotrophin-like survival signaling and protect neurons against apoptosis. | Molecular pharmacology 20051001 |
| Distinct domains of Bcl-XL are involved in Bax and Bad antagonism and in apoptosis inhibition. | Experimental cell research 20051001 |
| T-cadherin protects endothelial cells from oxidative stress-induced apoptosis. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051001 |
| Roles of cell-intrinsic and microenvironmental factors in photoreceptor cell differentiation. | Developmental biology 20051001 |
| Overexpression of regucalcin suppresses cell proliferation of cloned normal rat kidney proximal tubular epithelial NRK52E cells. | International journal of molecular medicine 20051001 |
| Upregulation of alpha globin promotes apoptotic cell death in the hematopoietic cell line FL5.12. | Apoptosis : an international journal on programmed cell death 20051001 |
| Rapid collapse of mitochondrial transmembrane potential in HL-60 cells and isolated mitochondria treated with anti-tumor 1,4-anthracenediones. | Anti-cancer drugs 20051001 |
| It works: combinatorial biosynthesis for generating novel glycosylated compounds. | Molecular microbiology 20051001 |
| Deciphering the late steps in the biosynthesis of the anti-tumour indolocarbazole staurosporine: sugar donor substrate flexibility of the StaG glycosyltransferase. | Molecular microbiology 20051001 |
| Induction of apoptosis-like mitochondrial impairment triggers antioxidant and Bcl-2-dependent keratinocyte differentiation. | The Journal of investigative dermatology 20051001 |
| Lysosomal membrane permeabilization during apoptosis--involvement of Bax? | International journal of experimental pathology 20051001 |
| A novel isoform of TUCAN is overexpressed in human cancer tissues and suppresses both caspase-8- and caspase-9-mediated apoptosis. | Cancer research 20051001 |
| Partial correction of abnormal cardiac development in caspase-8-deficient mice by cardiomyocyte expression of p 35. | Transgenic research 20051001 |
| Tobacco transcription factor WRKY1 is phosphorylated by the MAP kinase SIPK and mediates HR-like cell death in tobacco. | Molecular plant-microbe interactions : MPMI 20051001 |
| Role of chemokine signaling pathways in pancreatic islet rejection during allo- and xenotransplantation. | Transplantation proceedings 20051001 |
| Divergent regulation of Pyk2/CAKbeta phosphorylation by Ca2+ and cAMP in the hippocampus. | Biochimica et biophysica acta 20050930 |
| Rapid modulation of inhibitory synaptic currents in cerebellar Purkinje cells by BDNF. | Synapse (New York, N.Y.) 20050915 |
| Fluoxetine (Prozac) interaction with the mitochondrial voltage-dependent anion channel and protection against apoptotic cell death. | FEBS letters 20050912 |
| Huperzine A protects SHSY5Y neuroblastoma cells against oxidative stress damage via nerve growth factor production. | European journal of pharmacology 20050905 |
| PKC-delta sensitizes Kir3.1/3.2 channels to changes in membrane phospholipid levels after M3 receptor activation in HEK-293 cells. | American journal of physiology. Cell physiology 20050901 |
| Ionizing radiation alters myofilament calcium sensitivity in vascular smooth muscle: potential role of protein kinase C. | American journal of physiology. Regulatory, integrative and comparative physiology 20050901 |
| Apoptosis of ejaculated human sperm is induced by co-incubation with Chlamydia trachomatis lipopolysaccharide. | Human reproduction (Oxford, England) 20050901 |
| Endothelial intercellular adhesion molecule (ICAM)-2 regulates angiogenesis. | Blood 20050901 |
| The role of protein kinase C in regulation of TCDD-mediated CYP1A1 gene expression. | Toxicological sciences : an official journal of the Society of Toxicology 20050901 |
| Critical role of Mst1 in vascular remodeling after injury. | Arteriosclerosis, thrombosis, and vascular biology 20050901 |
| Visualization of synaptic vesicle movement in intact synaptic boutons using fluorescence fluctuation spectroscopy. | Biophysical journal 20050901 |
| Low concentrations of aggregated beta-amyloid induce neurite formation via the neurotrophin receptor p75. | Journal of molecular medicine (Berlin, Germany) 20050901 |
| An immunosorbent, nonradioactive p38 MAP kinase assay comparable to standard radioactive liquid-phase assays. | Analytical biochemistry 20050901 |
| Phosphorylation of octamer-binding transcriptional factor may be correlated with H2B histone gene repression during 12-O-tetradecanoylphorbol 13-acetate-dependent differentiation of HL-60 cells. | Oncology reports 20050901 |
| Constitutive proteasome-mediated turnover of Bfl-1/A1 and its processing in response to TNF receptor activation in FL5.12 pro-B cells convert it into a prodeath factor. | Cell death and differentiation 20050901 |
| Alzheimer disease beta-amyloid activity mimics cholesterol oxidase. | The Journal of clinical investigation 20050901 |
| A cross-talk between RNA splicing and signaling pathway alters Fas gene expression at post-transcriptional level: alternative splicing of Fas mRNA in the leukemic U937 cells. | The Journal of laboratory and clinical medicine 20050901 |
| Glucocorticoids inhibit cell death in ovarian cancer and up-regulate caspase inhibitor cIAP2. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050901 |
| Cytochrome P450 homolog is responsible for C-N bond formation between aglycone and deoxysugar in the staurosporine biosynthesis of Streptomyces sp. TP-A0274. | Bioscience, biotechnology, and biochemistry 20050901 |
| Na+/Mg2+ antiport in erythrocytes of spontaneously hypertensive rats: role of Mg2+ in the pathogenesis of hypertension. | Magnesium research 20050901 |
| GABA, progesterone and zona pellucida activation of PLA2 and regulation by MEK-ERK1/2 during acrosomal exocytosis in guinea pig spermatozoa. | FEBS letters 20050829 |
| ANG II increases 2-deoxyglucose uptake in mouse embryonic stem cells. | Life sciences 20050826 |
| Role of the executioner caspases during lens development. | The Journal of biological chemistry 20050826 |
| The synthesis of bioactive indolocarbazoles related to K-252a. | Organic & biomolecular chemistry 20050821 |
| DNA-PK-dependent phosphorylation of Ku70/80 is not required for non-homologous end joining. | DNA repair 20050815 |
| Ceramide regulation of the tumor suppressor phosphatase PTEN in rafts isolated from neurotumor cell lines. | Journal of neuroscience research 20050815 |
| Identification and bioactivities of IFN-gamma in rainbow trout Oncorhynchus mykiss: the first Th1-type cytokine characterized functionally in fish. | Journal of immunology (Baltimore, Md. : 1950) 20050815 |
| Characterization of a R115777-resistant human multiple myeloma cell line with cross-resistance to PS-341. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050815 |
| Changes in intracellular sodium, chlorine, and potassium concentrations in staurosporine-induced apoptosis. | Journal of cellular physiology 20050801 |
| Activation of MAP kinase by muscarinic cholinergic receptors induces cell proliferation and protein synthesis in human breast cancer cells. | Journal of cellular physiology 20050801 |
| Regulatory and necrotic volume increase in boar spermatozoa. | Journal of cellular physiology 20050801 |
| Dissection of bidirectional synaptic plasticity into saturable unidirectional processes. | Journal of neurophysiology 20050801 |
| Crystal structure of the Jak3 kinase domain in complex with a staurosporine analog. | Blood 20050801 |
| Calcium inflow-dependent protein kinase C activity is involved in the modulation of transmitter release in the neuromuscular junction of the adult rat. | Synapse (New York, N.Y.) 20050801 |
| A Ser/Thr cluster within the C-terminal domain of the rat prostaglandin receptor EP3alpha is essential for agonist-induced phosphorylation, desensitization and internalization. | British journal of pharmacology 20050801 |
| Combined effects of protein kinase inhibitors and 5-fluorouracil on CEA expression in human colon cancer cells. | Pharmacological research 20050801 |
| Signal transduction of phorbol 12-myristate 13-acetate (PMA)-induced growth inhibition of human monocytic leukemia THP-1 cells is reactive oxygen dependent. | Leukemia research 20050801 |
| Treatment with extracellular HSP70/HSC70 protein can reduce polyglutamine toxicity and aggregation. | Journal of neurochemistry 20050801 |
| Regulation of erythrocyte Na-K-2Cl cotransport by threonine phosphorylation. | Biochimica et biophysica acta 20050801 |
| Analysis of gene expression during staurosporine-induced neuronal differentiation of human prostate cancer cells. | Oncology reports 20050801 |
| A study of cytotoxic synergy of UCN-01 and flavopiridol in syngeneic pair of cell lines. | Investigational new drugs 20050801 |
| The co-chaperone p23 is degraded by caspases and the proteasome during apoptosis. | FEBS letters 20050801 |
| Possible involvement of phototropins in leaf movement of kidney bean in response to blue light. | Plant physiology 20050801 |
| Bradykinin B2 type receptor activation regulates fluid and electrolyte transport in the rabbit kidney. | Peptides 20050801 |
| Molecular basis for G2 arrest induced by 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine and consequences of checkpoint abrogation. | Cancer research 20050801 |
| Activation of phosphoinositide 3-kinase, protein kinase C, and extracellular signal-regulated kinase is required for oridonin-enhanced phagocytosis of apoptotic bodies in human macrophage-like U937 cells. | Journal of pharmacological sciences 20050801 |
| Defect of N-glycosylation is not directly related to congenital disorder of glycosylation Ia fibroblast sensitivity to staurosporine-induced cell death. | Pediatric research 20050801 |
| High-affinity peripheral benzodiazepine receptor ligand, PK11195, regulates protein phosphorylation in rat brain mitochondria under control of Ca(2+). | Journal of neurochemistry 20050801 |
| Protein phosphorylation is a prerequisite for intracellular Ca2+ release and ion channel control by nitric oxide and abscisic acid in guard cells. | The Plant journal : for cell and molecular biology 20050801 |
| The immunostimulatory peptide WKYMVm-NH activates bone marrow mouse neutrophils via multiple signal transduction pathways. | Scandinavian journal of immunology 20050801 |
| Ethanol-induced changes in the content of triglycerides, ceramides, and glucosylceramides in cultured neurons. | Alcoholism, clinical and experimental research 20050801 |
| Caspase-independent apoptosis is activated by diazepam-induced mitotic failure in HeLa cells, but not in human primary fibroblasts. | Apoptosis : an international journal on programmed cell death 20050801 |
| Signaling pathway in nerve growth factor induced histamine release from rat mast cells. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20050801 |
| Activation mutations of human c-KIT resistant to imatinib mesylate are sensitive to the tyrosine kinase inhibitor PKC412. | Blood 20050715 |
| Characterization of cAMP-dependent proteolysis of GATA-6. | Biochemical and biophysical research communications 20050715 |
| Differential regulation of ceramide in lipid-rich microdomains (rafts): antagonistic role of palmitoyl:protein thioesterase and neutral sphingomyelinase 2. | Journal of neuroscience research 20050715 |
| Alpha-kinase 1, a new component in apical protein transport. | The Journal of biological chemistry 20050708 |
| The properties of the mitochondrial megachannel in mitoplasts from human colon carcinoma cells are not influenced by Bax. | FEBS letters 20050704 |
| Is myosin light-chain phosphorylation a regulatory signal for the osmotic activation of the Na+-K+-2Cl- cotransporter? | American journal of physiology. Cell physiology 20050701 |
| AML-associated Flt3 kinase domain mutations show signal transduction differences compared with Flt3 ITD mutations. | Blood 20050701 |
| Glucose degradation products downregulate ZO-1 expression in human peritoneal mesothelial cells: the role of VEGF. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050701 |
| Apoptosis of human endothelial cells is accompanied by proteolytic processing of latent TGF-beta binding proteins and activation of TGF-beta. | Cell death and differentiation 20050701 |
| Cellular prion protein inhibits proapoptotic Bax conformational change in human neurons and in breast carcinoma MCF-7 cells. | Cell death and differentiation 20050701 |
| Activated mitofusin 2 signals mitochondrial fusion, interferes with Bax activation, and reduces susceptibility to radical induced depolarization. | The Journal of biological chemistry 20050701 |
| Volatile C6-aldehydes and Allo-ocimene activate defense genes and induce resistance against Botrytis cinerea in Arabidopsis thaliana. | Plant & cell physiology 20050701 |
| VEGF-mediated survivin expression in neuroblastoma cells. | The Journal of surgical research 20050701 |
| Thymidine phosphorylase suppresses apoptosis induced by microtubule-interfering agents. | Biochemical pharmacology 20050701 |
| Effects of the kinase inhibitor CGP41251 (PKC 412) on lymphocyte activation and TNF-alpha production. | International immunopharmacology 20050701 |
| K252a inhibits proliferation of ovarian cancer cells by upregulating p21WAF1. | Oncology reports 20050701 |
| Bax translocates from cytosol to mitochondria in cardiac cells during apoptosis: development of a GFP-Bax-stable H9c2 cell line for apoptosis analysis. | American journal of physiology. Heart and circulatory physiology 20050701 |
| FLT3 inhibition in t(4;11)+ adult acute lymphoid leukaemia. | British journal of haematology 20050701 |
| An enzyme-linked immunosorbent assay to screen for inhibitors of the oncogenic anaplastic lymphoma kinase. | Haematologica 20050701 |
| Reducing the impact of binding of UCN-01 to human alpha1-acid glycoprotein by encapsulation in liposomes. | Biological & pharmaceutical bulletin 20050701 |
| Vitamin E prevents cell death induced by mild oxidative stress in chicken skeletal muscle cells. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20050701 |
| Expression of TNFalpha and its receptors R1 and R2 in human alveolar epithelial cells exposed to organic dust and the effects of 8-bromo-cAMP and protein kinase A modulation. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20050701 |
| Inhibition of aldosterone biosynthesis by staurosporine. | Biological chemistry 20050701 |
| hDLG/SAP97, a member of the MAGUK protein family, is a novel caspase target during cell-cell detachment in apoptosis. | Biological chemistry 20050701 |
| Caspase-3 dependent cleavage and activation of skeletal muscle phosphorylase b kinase. | Molecular and cellular biochemistry 20050701 |
| Fas-associated factor-1 mediates chemotherapeutic-induced apoptosis via death effector filament formation. | International journal of cancer 20050620 |
| Cleavage of cten by caspase-3 during apoptosis. | Oncogene 20050616 |
| The cyclin-dependent kinase inhibitor UCN-01 plus cisplatin in advanced solid tumors: a California cancer consortium phase I pharmacokinetic and molecular correlative trial. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050615 |
| The farnesyltransferase inhibitor L744832 potentiates UCN-01-induced apoptosis in human multiple myeloma cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050615 |
| The canonical intrinsic mitochondrial death pathway has a non-apoptotic role in signaling lens cell differentiation. | The Journal of biological chemistry 20050610 |
| Cyclophilin D: knocking on death's door. | Science's STKE : signal transduction knowledge environment 20050607 |
| Regulation of inflammatory response in neural cells in vitro by thiadiazolidinones derivatives through peroxisome proliferator-activated receptor gamma activation. | The Journal of biological chemistry 20050603 |
| Synthesis, modeling, and in vitro activity of (3'S)-epi-K-252a analogues. Elucidating the stereochemical requirements of the 3'-sugar alcohol on trkA tyrosine kinase activity. | Journal of medicinal chemistry 20050602 |
| Effect of the protein kinase C inhibitor, staurosporine, on the high dose of methamphetamine-induced behavioral sensitization to dizocilpine (MK-801). | Psychopharmacology 20050601 |
| Hormonal regulation on regucalcin mRNA expression in cloned normal rat kidney proximal tubular epithelial NRK52E cells. | Journal of cellular biochemistry 20050601 |
| Prostaglandin E2-induced modification of tetrodotoxin-resistant Na+ currents involves activation of both EP2 and EP4 receptors in neonatal rat nodose ganglion neurones. | British journal of pharmacology 20050601 |
| Parathormone sensitivity and responses to protein kinases in subclones of opossum kidney cells. | Pediatric nephrology (Berlin, Germany) 20050601 |
| Apoptosis and differentiation induced by staurosporine in granulosa tumor cells is coupled with activation of JNK and suppression of p38 MAPK. | International journal of oncology 20050601 |
| Beta-catenin cleavage in non-apoptotic cells with reduced cell adhesion activity. | International journal of molecular medicine 20050601 |
| Midostaurin upregulates eNOS gene expression and preserves eNOS function in the microcirculation of the mouse. | Nitric oxide : biology and chemistry 20050601 |
| The role of calcium desensitization in vascular hyporeactivity and its regulation after hemorrhagic shock in the rat. | Shock (Augusta, Ga.) 20050601 |
| Effect of staurosporine on N-glycosylation and cell adhesion to fibronectin of SW480 human colorectal adenocarcinoma cells. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050601 |
| STAT3 is essential for Hodgkin lymphoma cell proliferation and is a target of tyrphostin AG17 which confers sensitization for apoptosis. | Leukemia 20050601 |
| Mechanisms involved in the contraction of intrahepatic portal vein branches by clomipramine and oxethazaine in isolated perfused rat livers. | Journal of pharmacological sciences 20050601 |
| Adeno-associated virus 2-mediated intratumoral prostate cancer gene therapy: long-term maspin expression efficiently suppresses tumor growth. | Human gene therapy 20050601 |
| N-benzoylstaurosporine (PKC412) inhibits Akt kinase inducing apoptosis in multiple myeloma cells. | Leukemia & lymphoma 20050601 |
| A comparison of the roles of protein kinase C in long-term potentiation in rat hippocampal areas CA1 and CA3. | Cellular and molecular neurobiology 20050601 |
| Cycloheximide-mediated sensitization to TNF-alpha-induced apoptosis in human colorectal cancer cell line COLO 205; role of FLIP and metabolic inhibitors. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20050601 |
| Role of protein kinase C in Ca channel blocker-induced renal arteriolar dilation in spontaneously hypertensive rats--studies in the isolated perfused hydronephrotic kidney. | The Keio journal of medicine 20050601 |
| Using IMAP technology to identify kinase inhibitors: comparison with a substrate depletion approach and analysis of the nature of false positives. | Combinatorial chemistry & high throughput screening 20050601 |
| Distinct roles for p53 transactivation and repression in preventing UCN-01-mediated abrogation of DNA damage-induced arrest at S and G2 cell cycle checkpoints. | Oncogene 20050526 |
| Phosphorylation of rat liver mitochondrial glycerol-3-phosphate acyltransferase by casein kinase 2. | The Journal of biological chemistry 20050520 |
| PKCalpha is involved in phorbol ester TPA-mediated stabilization of p14ARF. | Biochemical and biophysical research communications 20050520 |
| Non-equilibration of hydrostatic pressure in blebbing cells. | Nature 20050519 |
| Metallothionein overexpression and resistance to toxic stress. | Toxicology letters 20050516 |
| Role of Ras/PKCzeta/MEK/ERK1/2 signaling pathway in angiotensin II-induced vascular smooth muscle cell proliferation. | Regulatory peptides 20050515 |
| Early apoptotic and late necrotic components associated with altered Ca2+ homeostasis in a peptide-delivery model of polyglutamine-induced neuronal death. | Journal of neuroscience research 20050515 |
| Protective effect of FK506 against apoptosis of SH-SY5Y cells correlates with regulation of the serum inducible kinase gene. | Biochemical pharmacology 20050515 |
| Protein kinase D specifically mediates apoptosis signal-regulating kinase 1-JNK signaling induced by H2O2 but not tumor necrosis factor. | The Journal of biological chemistry 20050513 |
| Vitamin D fails to prevent serum starvation- or staurosporine-induced apoptosis in human and rat osteosarcoma-derived cell lines. | Biochemical and biophysical research communications 20050513 |
| Long CGG-repeat tracts are toxic to human cells: implications for carriers of Fragile X premutation alleles. | FEBS letters 20050509 |
| Insulin stimulates Ca2+ uptake via PKC, cAMP, and p38 MAPK in mouse embryonic stem cells. | Life sciences 20050506 |
| Caspase-9 can antagonize p53-induced apoptosis by generating a p76(Rb) truncated form of Rb. | Oncogene 20050505 |
| Isoflurane induces a protein kinase C alpha-dependent increase in cell-surface protein level and activity of glutamate transporter type 3. | Molecular pharmacology 20050501 |
| Cooperation of amphiregulin and insulin-like growth factor-1 inhibits Bax- and Bad-mediated apoptosis via a protein kinase C-dependent pathway in non-small cell lung cancer cells. | The Journal of biological chemistry 20050501 |
| Influence of caspase activity on micronuclei detection: a possible role for caspase-3 in micronucleation. | Mutagenesis 20050501 |
| The role of macrophages in the in vitro generation of extracellular DNA from apoptotic and necrotic cells. | Immunology 20050501 |
| Less keratinocyte-derived factors related to more keratinocyte apoptosis in depigmented than normally pigmented suction-blistered epidermis may cause passive melanocyte death in vitiligo. | The Journal of investigative dermatology 20050501 |
| Phytoestrogens modulate prostaglandin production in bovine endometrium: cell type specificity and intracellular mechanisms. | Experimental biology and medicine (Maywood, N.J.) 20050501 |
| Matrix metalloproteinase-1 associates with intracellular organelles and confers resistance to lamin A/C degradation during apoptosis. | The American journal of pathology 20050501 |
| Drugging cell cycle kinases in cancer therapy. | Current drug targets 20050501 |
| Cardioprotective stress response in the human fetal heart. | The Journal of thoracic and cardiovascular surgery 20050501 |
| Pigment epithelium-derived factor (PEDF) promotes growth of pericytes through autocrine production of platelet-derived growth factor-B. | Microvascular research 20050501 |
| Sustained Akt/PKB activation and transient attenuation of c-jun N-terminal kinase in the inhibition of apoptosis by IGF-1 in vascular smooth muscle cells. | Apoptosis : an international journal on programmed cell death 20050501 |
| Evidence for a non-antioxidant, dose-dependent role of alpha -lipoic acid in caspase-3 and ERK2 activation in endothelial cells. | Apoptosis : an international journal on programmed cell death 20050501 |
| The hypereosinophilic syndrome: idiopathic or not, that is the question. | Haematologica 20050501 |
| Edotecarin: a novel topoisomerase I inhibitor. | Clinical colorectal cancer 20050501 |
| Citral is a new inducer of caspase-3 in tumor cell lines. | Planta medica 20050501 |
| Cytochrome c is released in a single step during apoptosis. | Cell death and differentiation 20050501 |
| Identification of phosphoproteins regulated by gibberellin in rice leaf sheath. | Plant molecular biology 20050501 |
| Signaling pathways in the biphasic effect of ANG II on Na+/H+ exchanger in T84 cells. | The Journal of membrane biology 20050501 |
| Molecular mechanism of the aryl hydrocarbon receptor activation by the fungicide iprodione in rainbow trout (Oncorhynchus mykiss) hepatocytes. | Aquatic toxicology (Amsterdam, Netherlands) 20050430 |
| Increasing the kinase specificity of k252a by protein surface recognition. | Organic letters 20050428 |
| Zinc-induced anti-apoptotic effects in SH-SY5Y neuroblastoma cells via the extracellular signal-regulated kinase 1/2. | Brain research. Molecular brain research 20050427 |
| Overexpression of the mineralocorticoid receptor protects against injury in PC12 cells. | Brain research. Molecular brain research 20050427 |
| Nerve growth factor rapidly increases muscarinic tone in mouse medial septum/diagonal band of Broca. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050427 |
| Survival function of protein kinase C{iota} as a novel nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-activated bad kinase. | The Journal of biological chemistry 20050422 |
| Growth-promoting effect of platelet-derived growth factor on rat cardiac myocytes. | Regulatory peptides 20050415 |
| Protein kinase C-mediated inhibition of renal Ca2+ ATPase by physiological concentrations of angiotensin II is reversed by AT1- and AT2-receptor antagonists. | Regulatory peptides 20050415 |
| PKC 412 sensitizes U1810 non-small cell lung cancer cells to DNA damage. | Experimental cell research 20050415 |
| Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors. | Cancer research 20050415 |
| Sensitization of stefin B-deficient thymocytes towards staurosporin-induced apoptosis is independent of cysteine cathepsins. | FEBS letters 20050411 |
| Pim-1 ligand-bound structures reveal the mechanism of serine/threonine kinase inhibition by LY294002. | The Journal of biological chemistry 20050408 |
| The protein kinase inhibitor, staurosporine, inhibits L-type Ca2+ current in rabbit atrial myocytes. | Biochemical and biophysical research communications 20050408 |
| Sutherlandia frutescens extracts can induce apoptosis in cultured carcinoma cells. | Journal of ethnopharmacology 20050408 |
| Hsp27 and Hsp70 administered in combination have a potent protective effect against FALS-associated SOD1-mutant-induced cell death in mammalian neuronal cells. | Brain research. Molecular brain research 20050404 |
| Glioblastoma cells deficient in DNA-dependent protein kinase are resistant to cell death. | Journal of cellular physiology 20050401 |
| Biotin uptake by human proximal tubular epithelial cells: cellular and molecular aspects. | American journal of physiology. Renal physiology 20050401 |
| Selective subunit antagonists suggest an inhibitory relationship between NR2B and NR2A-subunit containing N-methyl-D: -aspartate receptors in hippocampal slices. | Experimental brain research 20050401 |
| Effects of Schwann cell secreted factors on PC12 cell neuritogenesis and survival. | Journal of neurobiology 20050401 |
| Comprehensive analysis of the effect of phytoestrogen, daidzein, on a testicular cell line, using mRNA and protein expression profile. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050401 |
| Integrin alpha8beta1-fibronectin interactions promote cell survival via PI3 kinase pathway. | Biochemical and biophysical research communications 20050401 |
| N-methyl-D-aspartate and TrkB receptors protect neurons against glutamate excitotoxicity through an extracellular signal-regulated kinase pathway. | Journal of neuroscience research 20050401 |
| beta-Cryptoxanthin stimulates cell proliferation and transcriptional activity in osteoblastic MC3T3-E1 cells. | International journal of molecular medicine 20050401 |
| Role of extracellular matrix in regulation of staurosporine-induced apoptosis in breast cancer cells. | Oncology reports 20050401 |
| The N. gonorrhoeae type IV pilus stimulates mechanosensitive pathways and cytoprotection through a pilT-dependent mechanism. | PLoS biology 20050401 |
| Role of NAD-dependent deacetylases SIRT1 and SIRT2 in radiation and cisplatin-induced cell death in vertebrate cells. | Genes to cells : devoted to molecular & cellular mechanisms 20050401 |
| Review of UCN-01 development: a lesson in the importance of clinical pharmacology. | Journal of clinical pharmacology 20050401 |
| Effect of 7-hydroxystaurosporine on glioblastoma cell invasion and migration. | Acta pharmacologica Sinica 20050401 |
| RNA silencing of checkpoint regulators sensitizes p53-defective prostate cancer cells to chemotherapy while sparing normal cells. | Cancer research 20050401 |
| Alpha1-receptor or adenosine A1-receptor dependent pathway alone is not sufficient but summation of these pathways is required to achieve an ischaemic preconditioning effect in rabbits. | Clinical and experimental pharmacology & physiology 20050401 |
| Cleavage of L1 in exosomes and apoptotic membrane vesicles released from ovarian carcinoma cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050401 |
| Astroglial cytoprotection by erythropoietin pre-conditioning: implications for ischemic and degenerative CNS disorders. | Journal of neurochemistry 20050401 |
| Roles of SIRT1 and phosphoinositide 3-OH kinase/protein kinase C pathways in evodiamine-induced human melanoma A375-S2 cell death. | Journal of pharmacological sciences 20050401 |
| Induction method of tyrosine kinase A-mediated cell death in rat pheochromocytoma. | Biotechnology letters 20050401 |
| Muscarinic receptor stimulation activates a Ca(2+)-dependent Cl(-) conductance in rat distal colon. | The Journal of membrane biology 20050401 |
| The dynamics of autophagy visualized in live cells: from autophagosome formation to fusion with endo/lysosomes. | Autophagy 20050401 |
| Screening New Drugs for Immunotoxic Potential: II. Assessment of the Effects of Selective and Nonselective COX-2 Inhibitors on Complement Activation, Superoxide Anion Production and Leukocyte Chemotaxis and Migration Through Endothelial Cells. | Journal of immunotoxicology 20050401 |
| Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death. | Nature 20050331 |
| Apoptosis of mink lung epithelial cells by co-treatment of low-dose staurosporine and transforming growth factor-beta1 depends on the enhanced TGF-beta signaling and requires the decreased phosphorylation of PKB/Akt. | Biochemical and biophysical research communications 20050325 |
| Indifferently pursued or unowned drugs: who should lead where companies do not tread? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050320 |
| Phase I trial of the cyclin-dependent kinase inhibitor and protein kinase C inhibitor 7-hydroxystaurosporine in combination with Fluorouracil in patients with advanced solid tumors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050320 |
| Translocation of diacylglycerol kinase theta from cytosol to plasma membrane in response to activation of G protein-coupled receptors and protein kinase C. | The Journal of biological chemistry 20050318 |
| Mitochondrial-dependent, reactive oxygen species-independent apoptosis by myricetin: roles of protein kinase C, cytochrome c, and caspase cascade. | Biochemical pharmacology 20050315 |
| Contribution of protein kinase A and protein kinase C pathways in ultraviolet B-induced IL-8 expression by human keratinocytes. | Cytokine 20050307 |
| Flexible docking in solution using metadynamics. | Journal of the American Chemical Society 20050302 |
| Protein kinase C signaling as a survival pathway against CYP2E1-derived oxidative stress and toxicity in HepG2 cells. | The Journal of pharmacology and experimental therapeutics 20050301 |
| Activation of ferret erythrocyte Na+-K+-2Cl- cotransport by deoxygenation. | The Journal of physiology 20050301 |
| Mechanism of mitochondrial stress-induced resistance to apoptosis in mitochondrial DNA-depleted C2C12 myocytes. | Cell death and differentiation 20050301 |
| Nitric oxide inhibits caspase activation and apoptotic morphology but does not rescue neuronal death. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20050301 |
| Differential regulation by protein kinases of activity and cell surface expression of glutamate transporters in neuron-enriched cultures. | Neurochemistry international 20050301 |
| Expression of Smac/DIABLO in mouse preimplantation embryos and its correlation to apoptosis and fragmentation. | Molecular human reproduction 20050301 |
| A small molecule-kinase interaction map for clinical kinase inhibitors. | Nature biotechnology 20050301 |
| Staurosporine inhibits voltage-dependent K+ current through a PKC-independent mechanism in isolated coronary arterial smooth muscle cells. | Journal of cardiovascular pharmacology 20050301 |
| Combined pharmacological, mutational and cell biology approaches indicate that p53-dependent caspase 3 activation triggered by cellular prion is dependent on its endocytosis. | Journal of neurochemistry 20050301 |
| Rapamycin and UCN-01 synergistically induce apoptosis in human leukemia cells through a process that is regulated by the Raf-1/MEK/ERK, Akt, and JNK signal transduction pathways. | Molecular cancer therapeutics 20050301 |
| Hsp70 chaperones: cellular functions and molecular mechanism. | Cellular and molecular life sciences : CMLS 20050301 |
| Indirect phosphorylation-dependent modulation of postsynaptic nicotinic acetylcholine responses by 5-hydroxytryptamine. | The European journal of neuroscience 20050301 |
| Establishment of an immortalized porcine granulosa cell line (PGV) and the study on the potential mechanisms of PGV cell proliferation. | The Keio journal of medicine 20050301 |
| Interactive effects of phosphate deficiency, sucrose and light/dark conditions on gene expression of UDP-glucose pyrophosphorylase in Arabidopsis. | Journal of plant physiology 20050301 |
| [Cloning, expression, purification of protein kinase Cdelta and its preliminary application in drug lead compounds screening]. | Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20050301 |
| [Possibility of targeting FLT3 kinase for the treatment of leukemia]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20050301 |
| 1-Butanol interferes with phospholipase D1 and protein kinase Calpha association and inhibits phospholipase D1 basal activity. | Biochemical and biophysical research communications 20050225 |
| [New targets for molecular therapy of acute leukemia: a 'single-hit' or 'multiple-hit' strategy against signaling pathway]. | Zhonghua yi xue za zhi 20050223 |
| Farnesyltransferase inhibitors interact synergistically with the Chk1 inhibitor UCN-01 to induce apoptosis in human leukemia cells through interruption of both Akt and MEK/ERK pathways and activation of SEK1/JNK. | Blood 20050215 |
| Adenylyl cyclase-cAMP system inhibits thrombin-induced HSP27 in vascular smooth muscle cells. | Journal of cellular biochemistry 20050215 |
| Toll-like receptor 9 signaling can sensitize fibroblasts for apoptosis. | Immunology letters 20050215 |
| Regulation of hyaluronan binding by F-actin and colocalization of CD44 and phosphorylated ezrin/radixin/moesin (ERM) proteins in myeloid cells. | Experimental cell research 20050215 |
| Validation of pharmacodynamic assays to evaluate the clinical efficacy of an antisense compound (AEG 35156) targeted to the X-linked inhibitor of apoptosis protein XIAP. | British journal of cancer 20050214 |
| The mitotic spindle checkpoint is a critical determinant for topoisomerase-based chemotherapy. | The Journal of biological chemistry 20050211 |
| Mitogen-activated protein kinase-dependent apoptosis in norcan-tharidin-treated A375-S2 cells is proceeded by the activation of protein kinase C. | Chinese medical journal 20050205 |
| Caspase-3 inhibits the growth of breast cancer cells independent of protease activity. | Journal of cellular physiology 20050201 |
| p53 protein activates the transcription of human proliferating cell nuclear antigen in response to 4-nitroquinoline N-oxide treatment. | The international journal of biochemistry & cell biology 20050201 |
| Laminin-1 is phosphorylated by ecto-protein kinases of monocytes. | The international journal of biochemistry & cell biology 20050201 |
| Role of protein kinase C-epsilon (PKCepsilon) in isoflurane-induced cardioprotection. | British journal of anaesthesia 20050201 |
| Enhancement of Schwann cell myelin formation by K252a in the Trembler-J mouse dorsal root ganglion explant culture. | Journal of neuroscience research 20050201 |
| The MHC class II transactivator (CIITA) mRNA stability is critical for the HLA class II gene expression in myelomonocytic cells. | European journal of immunology 20050201 |
| alpha1A- but not alpha1B-adrenergic receptors precondition the ischemic heart by a staurosporine-sensitive, chelerythrine-insensitive mechanism. | Cardiovascular research 20050201 |
| Synergistic stimulatory effect of 12-O-tetradecanoylphorbol-13-acetate and capsaicin on macrophage differentiation in HL-60 and HL-525 human myeloid leukemia cells. | International journal of oncology 20050201 |
| Minocycline in phenotypic models of Huntington's disease. | Neurobiology of disease 20050201 |
| Endothelin-1 acts via protein kinase C to block KATP channels in rabbit coronary and pulmonary arterial smooth muscle cells. | Journal of cardiovascular pharmacology 20050201 |
| NF-kappa B activation is not required for Chlamydia trachomatis inhibition of host epithelial cell apoptosis. | Journal of immunology (Baltimore, Md. : 1950) 20050201 |
| Mitochondrial K(ATP) channels in respiratory neurons and their role in the hypoxic facilitation of rhythmic activity. | Brain research 20050201 |
| Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants. | Gastroenterology 20050201 |
| Regulation of alternative splicing of caspase-2 through an intracellular signaling pathway in response to pro-apoptotic stimuli. | The Journal of laboratory and clinical medicine 20050201 |
| Ultrastructural alterations in ciliated protozoa under heavy metal exposure. | Cell biology international 20050201 |
| Patterns of dentate granule cell responses to perforant path stimulation in epileptic mice with granule cell dispersion. | Epilepsy research 20050201 |
| Distinct properties of functional KCC2 expression in immature mouse hippocampal neurons in culture and in acute slices. | The European journal of neuroscience 20050201 |
| Stabilizing effects of extracellular ATP on synaptic efficacy and plasticity in hippocampal pyramidal neurons. | The European journal of neuroscience 20050201 |
| Development of a non-radioactive, 384-well format assay to detect inhibitors of the mitogen-activated protein kinase kinase 4. | Assay and drug development technologies 20050201 |
| Characterization of aurora-a in porcine oocytes and early embryos implies its functional roles in the regulation of meiotic maturation, fertilization and cleavage. | Zygote (Cambridge, England) 20050201 |
| Apoptosis and survival of osteoblast-like cells are regulated by surface attachment. | The Journal of biological chemistry 20050121 |
| Clinical anticancer drug development: targeting the cyclin-dependent kinases. | British journal of cancer 20050117 |
| HCO(3)(-)-independent rescue from apoptosis by stilbene derivatives in rat cardiomyocytes. | FEBS letters 20050117 |
| A phase I and pharmacokinetic study of short infusions of UCN-01 in patients with refractory solid tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050115 |
| Use of photoaffinity labeling and site-directed mutagenesis for identification of the key residue responsible for extraordinarily high affinity binding of UCN-01 in human alpha1-acid glycoprotein. | The Journal of biological chemistry 20050114 |
| Inositol hexakisphosphate kinase-2, a physiologic mediator of cell death. | The Journal of biological chemistry 20050114 |
| The broad-range cyclin-dependent kinase inhibitor UCN-01 induces apoptosis in colon carcinoma cells through transcriptional suppression of the Bcl-x(L) protein. | Oncogene 20050106 |
| The pseudorabies virus US3 protein kinase possesses anti-apoptotic activity that protects cells from apoptosis during infection and after treatment with sorbitol or staurosporine. | Virology 20050105 |
| Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412. | Blood 20050101 |
| LTD4 induces hyperresponsiveness to histamine in bovine airway smooth muscle: role of SR-ATPase Ca2+ pump and tyrosine kinase. | American journal of physiology. Lung cellular and molecular physiology 20050101 |
| Reduced macrophage apoptosis is associated with accelerated atherosclerosis in low-density lipoprotein receptor-null mice. | Arteriosclerosis, thrombosis, and vascular biology 20050101 |
| Morphological irregularities and features of resistance to apoptosis in the dcp-1/pita double mutated egg chambers during Drosophila oogenesis. | Cell motility and the cytoskeleton 20050101 |
| Regulated sarcolemmal localization of the muscle-specific ClC-1 chloride channel. | Experimental neurology 20050101 |
| Phosphorylation of Plk1 at S137 and T210 is inhibited in response to DNA damage. | Cell cycle (Georgetown, Tex.) 20050101 |
| Staurosporine promotes endothelial cell assembly and FAK phosphorylation during in vitro angiogenesis. | Journal of cardiovascular pharmacology 20050101 |
| Saturated free fatty acids and apoptosis in microvascular mesangial cells: palmitate activates pro-apoptotic signaling involving caspase 9 and mitochondrial release of endonuclease G. | Cardiovascular diabetology 20050101 |
| [Abrogation effect of UCN-01 on radiation-induced G2 phase arrest of tumor cells and its mechanism]. | Ai zheng = Aizheng = Chinese journal of cancer 20050101 |
| Role of granulocyte-macrophage colony-stimulating factor in preventing apoptosis and improving functional outcome in experimental spinal cord contusion injury. | Journal of neurosurgery. Spine 20050101 |
| Chlamydia pneumoniae induces aponecrosis in human aortic smooth muscle cells. | BMC microbiology 20050101 |
| The neuroprotective effects of K252a through inhibiting MLK3/MKK7/JNK3 signaling pathway on ischemic brain injury in rat hippocampal CA1 region. | Neuroscience 20050101 |
| Cross-talk between phosphatidic acid and ceramide during ethanol-induced apoptosis in astrocytes. | BMC pharmacology 20050101 |
| Production of intracellular superoxide mediates dithiothreitol-dependent inhibition of apoptotic cell death. | Antioxidants & redox signaling 20050101 |
| Differential role of hydrogen peroxide and staurosporine in induction of cell death in glioblastoma cells lacking DNA-dependent protein kinase. | Apoptosis : an international journal on programmed cell death 20050101 |
| Involvement of bovine leukemia virus in induction and inhibition of apoptosis. | Microbes and infection 20050101 |
| Evaluation of dendritic cells loaded with apoptotic cancer cells or expressing tumour mRNA as potential cancer vaccines against leukemia. | BMC cancer 20050101 |
| Analysis of phosphorylation of human heat shock factor 1 in cells experiencing a stress. | BMC biochemistry 20050101 |
| Differential modulation of microglia superoxide anion and thromboxane B2 generation by the marine manzamines. | BMC pharmacology 20050101 |
| Selective translocation of protein kinase c isozymes by PAF in rabbit platelets. | Prostaglandins & other lipid mediators 20050101 |
| Inactivation of MAP kinase signalling in Myc transformed cells and rescue by LiCl inhibition of GSK3. | Molecular cancer 20050101 |
| Blockage of cyclin cdk's, PKC and phosphoinositol 3-kinase pathways leads to augmentation of apoptosis in drug-resistant leukemia cells: evidence for interactive effects of flavopiridol, LY 294002, roscovitine,wortmannin and UCN-01. | Anticancer research 20050101 |
| Acquisition of anoikis resistance in human osteosarcoma cells does not alter sensitivity to chemotherapeutic agents. | BMC cancer 20050101 |
| Altered expression of membrane-bound and soluble CD95/Fas contributes to the resistance of fibrotic lung fibroblasts to FasL induced apoptosis. | Respiratory research 20050101 |
| Glycoprotein isolated from Solanum nigrum L. modulates the apoptotic-related signals in 12-O-tetradecanoylphorbol 13-acetate-stimulated MCF-7 cells. | Journal of medicinal food 20050101 |
| P2Y1 and cysteinyl leukotriene receptors mediate purine and cysteinyl leukotriene co-release in primary cultures of rat microglia. | International journal of immunopathology and pharmacology 20050101 |
| High-throughput technology: green fluorescent protein to monitor cell death. | Methods in molecular medicine 20050101 |
| Maspin overexpression modulates tumor cell apoptosis through the regulation of Bcl-2 family proteins. | BMC cancer 20050101 |
| High-throughput kinase assays with protein substrates using fluorescent polymer superquenching. | BMC biotechnology 20050101 |
| Enhanced detergent extraction for analysis of membrane proteomes by two-dimensional gel electrophoresis. | Proteome science 20050101 |
| Effects of aldosterone and mineralocorticoid receptor blockade on intracellular electrolytes. | Heart failure reviews 20050101 |
| PIKE GTPase signaling and function. | International journal of biological sciences 20050101 |
| Involvement of mitochondrial potential and calcium buffering capacity in minocycline cytoprotective actions. | Neuroscience 20050101 |
| Communication and re-use of chemical information in bioscience. | BMC bioinformatics 20050101 |
| ClC-3-independent sensitivity of apoptosis to Cl- channel blockers in mouse cardiomyocytes. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20050101 |
| Inhibition of PACAP activity by a receptor antagonist results in changes in cell cycle and apoptotic proteins in chick neuroblasts. | Journal of molecular neuroscience : MN 20050101 |
| PAN-811 (3-aminopyridine-2-carboxaldehyde thiosemicarbazone), a novel neuroprotectant, elicits its function in primary neuronal cultures by up-regulating Bcl-2 expression. | Neuroscience 20050101 |
| Expressional and functional studies of Wolframin, the gene function deficient in Wolfram syndrome, in mice and patient cells. | Experimental gerontology 20050101 |
| Mechanism and characteristics of stimuli-dependent ROS generation in undifferentiated HL-60 cells. | Antioxidants & redox signaling 20050101 |
| Glycoprotein isolated from Solanum nigrum L. kills HT-29 cells through apoptosis. | Journal of medicinal food 20050101 |
| BDNF acutely modulates synaptic transmission and calcium signalling in developing cortical neurons. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20050101 |
| The role of tropomyosin-related kinase receptors in neurotrophin-induced rapid eye movement sleep in the cat. | Neuroscience 20050101 |
| Signaling pathways mediating a selective induction of nitric oxide synthase II by tumor necrosis factor alpha in nerve growth factor-responsive cells. | Journal of neuroinflammation 20050101 |
| Carbamazepine enhances the activity of glutamate transporter type 3 via phosphatidylinositol 3-kinase. | Epilepsy research 20050101 |
| Anthracyclines, proteasome activity and multi-drug-resistance. | BMC cancer 20050101 |
| New concepts in the treatment of acute myeloid malignancies: selected pathways for targeted therapy. | Journal of biological regulators and homeostatic agents 20050101 |
| ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversal. | Cancer cell international 20050101 |
| Sex hormone modulation of cell growth and apoptosis of the human monocytic/macrophage cell line. | Arthritis research & therapy 20050101 |
| Novel phorbol esters exert dichotomous effects on inhibition of HIV-1 infection and activation of latent HIV-1 expression. | Antiviral chemistry & chemotherapy 20050101 |
| Differential signaling mechanisms regulate expression of CC chemokine receptor-2 during monocyte maturation. | Journal of inflammation (London, England) 20050101 |
| Inhibitors of cyclin-dependent kinase modulators for cancer therapy. | Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques 20050101 |
| Effect of a small molecule inhibitor of nuclear factor-kappaB nuclear translocation in a murine model of arthritis and cultured human synovial cells. | Arthritis research & therapy 20050101 |
| Potassium and sodium balance in U937 cells during apoptosis with and without cell shrinkage. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20050101 |
| ERK-dependent signaling pathway and transcriptional factor Ets-1 regulate matrix metalloproteinase-9 production in transforming growth factor-beta1 stimulated glomerular podocytes. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20050101 |
| Multiple phosphorylation events control mitotic degradation of the muscle transcription factor Myf5. | BMC biochemistry 20050101 |
| TGF-beta1 and serum both stimulate contraction but differentially affect apoptosis in 3D collagen gels. | Respiratory research 20050101 |
| Selective apoptotic behaviour of bovine herpesvirus 1 in an epithelial-like microenvironment. | Acta veterinaria Hungarica 20050101 |
| c-Abl is required for staurosporine-induced caspase activity. | Proceedings of the Western Pharmacology Society 20050101 |
| Transcriptional upregulation of the human MRP2 gene expression by serine/threonine protein kinase inhibitors. | Journal of biological regulators and homeostatic agents 20050101 |
| Synthes Award for Resident Research on Spinal Cord and Spinal Column Injury: granulocyte macrophage colony stimulating factor (GM-CSF) prevents apoptosis and improves functional outcome in experimental spinal cord contusion injury. | Clinical neurosurgery 20050101 |
| Interaction of LDL and platelets in ischaemic and ischaemic risk subjects. | Indian journal of clinical biochemistry : IJCB 20050101 |
| Preapoptotic chromatin condensation upstream of the mitochondrial checkpoint. | The Journal of biological chemistry 20041231 |
| A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase. | The Journal of biological chemistry 20041231 |
| Linking alterations in tau phosphorylation and cleavage during neuronal apoptosis. | The Journal of biological chemistry 20041224 |
| A novel inhibitor that protects apoptotic DNA fragmentation catalyzed by DNase gamma. | Biochemical and biophysical research communications 20041224 |
| Role of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1. | Science (New York, N.Y.) 20041224 |
| Cardiomyocyte apoptosis triggered by RAFTK/pyk2 via Src kinase is antagonized by paxillin. | The Journal of biological chemistry 20041217 |
| Regulation of stability of cyclin-dependent kinase CDK11p110 and a caspase-processed form, CDK11p46, by Hsp90. | The Biochemical journal 20041215 |
| Diosgenin dose-dependent apoptosis and differentiation induction in human erythroleukemia cell line and sedimentation field-flow fractionation monitoring. | Analytical biochemistry 20041215 |
| Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 1. Structure-activity relationships of the 4-aryl group. | Journal of medicinal chemistry 20041202 |
| Cathepsin B-independent abrogation of cell death by CA-074-OMe upstream of lysosomal breakdown. | Cell death and differentiation 20041201 |
| BCL-xL-dependent light scattering by apoptotic cells. | Biophysical journal 20041201 |
| Staurosporine-induced G2/M arrest in primary effusion lymphoma BCBL-1 cells. | Annals of hematology 20041201 |
| Intrahepatic flow disturbance by clomipramine in the isolated perfused rat liver. | Biochemical pharmacology 20041201 |
| Externalization of endogenous annexin A5 participates in apoptosis of rat cardiomyocytes. | Cardiovascular research 20041201 |
| Role of albumin in osteoblastic cells: enhancement of cell proliferation and suppression of alkaline phosphatase activity. | International journal of molecular medicine 20041201 |
| Enhancement of radiation cytotoxicity by UCN-01 in non-small cell lung carcinoma cells. | Radiation research 20041201 |
| A general technique to rank protein-ligand binding affinities and determine allosteric versus direct binding site competition in compound mixtures. | Journal of the American Chemical Society 20041201 |
| Thyrotropin (TSH)-induced production of vascular endothelial growth factor in thyroid cancer cells in vitro: evaluation of TSH signal transduction and of angiogenesis-stimulating growth factors. | The Journal of clinical endocrinology and metabolism 20041201 |
| Phosphorylation and hypoxia-induced heme oxygenase-1 gene expression in cardiomyocytes. | Journal of cardiac failure 20041201 |
| [Translocation of orphan receptor TR3 from nuclei to mitochondria induced by staurosporine]. | Ai zheng = Aizheng = Chinese journal of cancer 20041201 |
| [Effects of methyl jasmonate treatment on the hydrolytic activity and phosphorylation level of plasma membrane H+-ATPase in mung bean (Vigna radiata L.) hypocotyls]. | Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology 20041201 |
| Apoptotic cell death and amyloid precursor protein signaling in neuroblastoma SH-SY5Y cells. | Annals of the New York Academy of Sciences 20041201 |
| Human alphaA- and alphaB-crystallins prevent UVA-induced apoptosis through regulation of PKCalpha, RAF/MEK/ERK and AKT signaling pathways. | Experimental eye research 20041201 |
| Cytoprotective function of sAppalpha in human keratinocytes. | European journal of cell biology 20041201 |
| Catalytic domain crystal structure of protein kinase C-theta (PKCtheta). | The Journal of biological chemistry 20041126 |
| Apoptotic topoisomerase I-DNA complexes induced by staurosporine-mediated oxygen radicals. | The Journal of biological chemistry 20041126 |
| Full-length expanded ataxin-3 enhances mitochondrial-mediated cell death and decreases Bcl-2 expression in human neuroblastoma cells. | Biochemical and biophysical research communications 20041126 |
| Antisense oligonucleotide against GTPase Rab5b inhibits metabotropic agonist DHPG-induced neuroprotection. | Brain research 20041126 |
| Activation of mitochondrial apoptotic pathway in mantle cell lymphoma: high sensitivity to mitoxantrone in cases with functional DNA-damage response genes. | Oncogene 20041125 |
| Synthesis and biological evaluation of 1-aryl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of cyclin-dependent kinases. | Journal of medicinal chemistry 20041118 |
| Amyloid beta(1-42) and its beta(25-35) fragment induce activation and membrane translocation of cytosolic phospholipase A2 in bovine retina capillary pericytes. | Biochimica et biophysica acta 20041108 |
| Gastrin and interleukin-1beta stimulate growth factor secretion from cultured rabbit gastric parietal cells. | Life sciences 20041105 |
| Primary granule release from human neutrophils is potentiated by soluble fibrinogen through a mechanism depending on multiple intracellular signaling pathways. | American journal of physiology. Cell physiology 20041101 |
| Enhancement of stress-induced apoptosis in B-lineage cells by caspase-9 inhibitor. | Blood 20041101 |
| Extracellular Mg(2+) blocks endothelin-1-induced contraction through the inhibition of non-selective cation channels in coronary smooth muscle. | Pflugers Archiv : European journal of physiology 20041101 |
| Leptin inhibits lysophosphatidic acid-induced intracellular calcium rise by a protein kinase C-dependent mechanism. | Journal of cellular physiology 20041101 |
| Uncoupling protein-3 sensitizes cells to mitochondrial-dependent stimulus of apoptosis. | Journal of cellular physiology 20041101 |
| Increased sensitivity of early apoptotic cells to complement-mediated lysis. | European journal of immunology 20041101 |
| Somatic cell apoptosis markers and pathways in human ejaculated sperm: potential utility as indicators of sperm quality. | Molecular human reproduction 20041101 |
| Heterologous desensitization of the sphingosine-1-phosphate receptors by purinoceptor activation in renal mesangial cells. | British journal of pharmacology 20041101 |
| Chk1 versus Cdc25: chking one's levels of cellular proliferation. | Cell cycle (Georgetown, Tex.) 20041101 |
| Cell death, BAX activation, and HMGB1 release during infection with Chlamydia. | Microbes and infection 20041101 |
| Fhit-deficient normal and cancer cells are mitomycin C and UVC resistant. | British journal of cancer 20041101 |
| Plakin proteins are coordinately cleaved during apoptosis but preferentially through the action of different caspases. | Experimental dermatology 20041101 |
| Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES- derived cell model of primary Parkinsonism. | PLoS biology 20041101 |
| Protein phosphorylation in Nicotiana tabacum cells in response to perception of lipopolysaccharides from Burkholderia cepacia. | Phytochemistry 20041101 |
| The response of phospholipase C/protein kinase C and adenylyl cyclase/protein kinase A pathways in porcine theca interna cells to opioid agonist FK 33-824. | Domestic animal endocrinology 20041101 |
| Alpha-tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons. | Neuropharmacology 20041101 |
| 7-hydroxystaurosporine (UCN-01) inhibition of Akt Thr308 but not Ser473 phosphorylation: a basis for decreased insulin-stimulated glucose transport. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041101 |
| Inhibitory effect of epidermal growth factor on resveratrol-induced apoptosis in prostate cancer cells is mediated by protein kinase C-alpha. | Molecular cancer therapeutics 20041101 |
| Internalization of the human CRF receptor 1 is independent of classical phosphorylation sites and of beta-arrestin 1 recruitment. | European journal of biochemistry 20041101 |
| Biological targets of antitumor indolocarbazoles bearing a sugar moiety. | Current medicinal chemistry. Anti-cancer agents 20041101 |
| Bone cell survival in microgravity: evidence that modeled microgravity increases osteoblast sensitivity to apoptogens. | Annals of the New York Academy of Sciences 20041101 |
| Signal transduction of ET-1 in contraction of cerebral arteries. | Journal of cardiovascular pharmacology 20041101 |
| DNA damage-induced accumulation of Rad18 protein at stalled replication forks in mammalian cells involves upstream protein phosphorylation. | Biochemical and biophysical research communications 20041022 |
| Dual signaling by mGluR5a results in bi-directional modulation of N-type Ca2+ channels. | FEBS letters 20041022 |
| A three-dimensional in silico pharmacophore model for inhibition of Plasmodium falciparum cyclin-dependent kinases and discovery of different classes of novel Pfmrk specific inhibitors. | Journal of medicinal chemistry 20041021 |
| Delivery of Bcl-XL or its BH4 domain by protein transduction inhibits apoptosis in human islets. | Biochemical and biophysical research communications 20041015 |
| Overexpression of regucalcin suppresses cell death and apoptosis in cloned rat hepatoma H4-II-E cells induced by lipopolysaccharide, PD 98059, dibucaine, or Bay K 8644. | Journal of cellular biochemistry 20041015 |
| Effect of p75 neurotrophin receptor antagonist on disease progression in transgenic amyotrophic lateral sclerosis mice. | Journal of neuroscience research 20041015 |
| Mitochondrial survivin inhibits apoptosis and promotes tumorigenesis. | The Journal of clinical investigation 20041015 |
| Apoptosis protease activator protein-1 expression is dispensable for response of human melanoma cells to distinct proapoptotic agents. | Cancer research 20041015 |
| Effects of alpha1-acid glycoprotein on the clinical pharmacokinetics of 7-hydroxystaurosporine. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041015 |
| Caspase-3-induced truncation of type 1 inositol trisphosphate receptor accelerates apoptotic cell death and induces inositol trisphosphate-independent calcium release during apoptosis. | The Journal of biological chemistry 20041008 |
| The three-dimensional structure of the ZAP-70 kinase domain in complex with staurosporine: implications for the design of selective inhibitors. | The Journal of biological chemistry 20041008 |
| Asbestos induces tissue factor in Beas-2B cells via PI3 kinase-PKC-mediated signaling. | Journal of toxicology and environmental health. Part A 20041008 |
| Endothelins induce ETB receptor-mediated mechanical hypernociception in rat hindpaw: roles of cAMP and protein kinase C. | European journal of pharmacology 20041006 |
| Differential DNases are selectively used in neuronal apoptosis depending on the differentiation state. | Cell death and differentiation 20041001 |
| BAD is a pro-survival factor prior to activation of its pro-apoptotic function. | The Journal of biological chemistry 20041001 |
| PI3K mediates protection against TRAIL-induced apoptosis in primary human melanocytes. | Cell death and differentiation 20041001 |
| Peroxiredoxin III, a mitochondrion-specific peroxidase, regulates apoptotic signaling by mitochondria. | The Journal of biological chemistry 20041001 |
| Parathyroid hormone increases cytosolic calcium in neonatal nephron through protein kinase C pathway. | Pediatric nephrology (Berlin, Germany) 20041001 |
| alpha-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid subtype glutamate receptor (AMPAR) endocytosis is essential for N-methyl-D-aspartate-induced neuronal apoptosis. | The Journal of biological chemistry 20041001 |
| Secreted proteins from Neisseria meningitidis mediate differential human gene expression and immune activation. | Cellular microbiology 20041001 |
| Mechanisms intrinsic to 5-HT2B receptor-induced potentiation of NMDA receptor responses in frog motoneurones. | British journal of pharmacology 20041001 |
| Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels. | Circulation research 20041001 |
| Glutamate-dependent transcriptional regulation of GLAST: role of PKC. | Journal of neurochemistry 20041001 |
| Bone morphogenetic proteins regulate ionotropic glutamate receptors in human retina. | The European journal of neuroscience 20041001 |
| Reduction in endogenous parkin levels renders glial cells sensitive to both caspase-dependent and caspase-independent cell death. | The European journal of neuroscience 20041001 |
| Signalling pathways regulating human neutrophil migration induced by secretory phospholipases A2. | Toxicon : official journal of the International Society on Toxinology 20041001 |
| HGF protects corneal epithelial cells from apoptosis by the PI-3K/Akt-1/Bad- but not the ERK1/2-mediated signaling pathway. | Investigative ophthalmology & visual science 20041001 |
| Phosphatidylinositol 3-kinase (PI-3K)/Akt but not PI-3K/p70 S6 kinase signaling mediates IGF-1-promoted lens epithelial cell survival. | Investigative ophthalmology & visual science 20041001 |
| Apoptosis resistance of MCF-7 breast carcinoma cells to ionizing radiation is independent of p53 and cell cycle control but caused by the lack of caspase-3 and a caffeine-inhibitable event. | Cancer research 20041001 |
| Biochemical characterization of the tobacco 42-kD protein kinase activated by osmotic stress. | Plant physiology 20041001 |
| The dietary isothiocyanate sulforaphane targets pathways of apoptosis, cell cycle arrest, and oxidative stress in human pancreatic cancer cells and inhibits tumor growth in severe combined immunodeficient mice. | Molecular cancer therapeutics 20041001 |
| Combinations of 5-fluorouracil with UCN-01 or staurosporine. | Nucleosides, nucleotides & nucleic acids 20041001 |
| Sphingosine 1-phosphate breakdown in platelets. | Journal of biochemistry 20041001 |
| Inhibition of 5-lipoxygenase and leukotriene C4 synthase in human blood cells by thymoquinone. | Journal of enzyme inhibition and medicinal chemistry 20041001 |
| Implications of p53 in growth arrest and apoptosis on combined treatment of human Mammary epithelial cells with topotecan and UCN-01. | Journal of experimental therapeutics & oncology 20041001 |
| Evidence for protein kinase involvement in long-term postsynaptic excitation of intrinsic primary afferent neurons in the intestine. | Autonomic neuroscience : basic & clinical 20040930 |
| The endocytotic pathway is required for increased A beta 42 secretion during apoptosis. | Brain research. Molecular brain research 20040928 |
| Functional characterization of peanut serine/threonine/tyrosine protein kinase: molecular docking and inhibition kinetics with tyrosine kinase inhibitors. | Biochemistry 20040928 |
| Exploring the pharmacology of the leukotriene B4 receptor BLT1, without the confounding effects of BLT2. | European journal of pharmacology 20040919 |
| Mechanisms of hydroxyl radical-induced contraction of rat aorta. | European journal of pharmacology 20040919 |
| Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone promotes functional cooperation of Bcl2 and c-Myc through phosphorylation in regulating cell survival and proliferation. | The Journal of biological chemistry 20040917 |
| Purification and characterization of a PMA-stimulated kinase and identification of PMA-induced phosphorylation of a polypeptide that is dephosphorylated by low temperature in Brassica juncea. | Biochemical and biophysical research communications 20040917 |
| Identifying and characterizing a novel activating mutation of the FLT3 tyrosine kinase in AML. | Blood 20040915 |
| Prediction of resistance to small molecule FLT3 inhibitors: implications for molecularly targeted therapy of acute leukemia. | Cancer research 20040915 |
| Potentiation of cytotoxicity of topoisomerase i poison by concurrent and sequential treatment with the checkpoint inhibitor UCN-01 involves disparate mechanisms resulting in either p53-independent clonogenic suppression or p53-dependent mitotic catastrophe. | Cancer research 20040915 |
| SdFFF monitoring of cellular apoptosis induction by diosgenin and different inducers in the human 1547 osteosarcoma cell line. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040905 |
| Insulin induces alpha1B-adrenergic receptor phosphorylation and desensitization. | Life sciences 20040903 |
| Overexpression of human KCNA5 increases IK V and enhances apoptosis. | American journal of physiology. Cell physiology 20040901 |
| Loss of lineage antigens is a common feature of apoptotic lymphocytes. | Journal of leukocyte biology 20040901 |
| High glucose inhibits fructose uptake in renal proximal tubule cells: involvement of cAMP, PLC/PKC, p44/42 MAPK, and cPLA2. | Journal of cellular physiology 20040901 |
| Intracellular and extracellular angiotensin II enhance the L-type calcium current in the failing heart. | Hypertension (Dallas, Tex. : 1979) 20040901 |
| Activation of apoptosis and caspase-3 in zebrafish early gastrulae. | Developmental dynamics : an official publication of the American Association of Anatomists 20040901 |
| Autocrine regulation of nerve growth factor expression by Trk receptors. | Journal of neurochemistry 20040901 |
| Tyrosine hydroxylase induction by basic fibroblast growth factor and cyclic AMP analogs in striatal neural stem cells: role of ERK1/ERK2 mitogen-activated protein kinase and protein kinase C. | The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20040901 |
| Apoptotic topoisomerase I-DNA complexes induced by oxygen radicals and mitochondrial dysfunction. | Cell cycle (Georgetown, Tex.) 20040901 |
| Human alphaA- and alphaB-crystallins prevent UVA-induced apoptosis through regulation of PKCalpha, RAF/MEK/ERK and AKT signaling pathways. | Experimental eye research 20040901 |
| Involvement of cyclin dependent kinase 5 and its activator p35 in staurosporine-induced apoptosis of cortical neurons. | Acta pharmacologica Sinica 20040901 |
| Apoptotic cell death influences the signaling activity of the amyloid precursor protein through ShcA and Grb2 adaptor proteins in neuroblastoma SH-SY5Y cells. | Journal of neurochemistry 20040901 |
| OPA3 gene mutations responsible for autosomal dominant optic atrophy and cataract. | Journal of medical genetics 20040901 |
| Chronic morphine treatment reduces recovery from opioid desensitization. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040901 |
| Src family tyrosine kinases inhibit single L-type: Ca2+ channel activity in human atrial myocytes. | Journal of molecular and cellular cardiology 20040901 |
| CHK1 and CHK2 are differentially involved in mismatch repair-mediated 6-thioguanine-induced cell cycle checkpoint responses. | Molecular cancer therapeutics 20040901 |
| Influence of hypotonic shock on glutamate and GABA uptake in rat brain synaptosomes. | Neurochemical research 20040901 |
| Tryptophan residues play an important role in the extraordinarily high affinity binding interaction of UCN-01 to human alpha-1-acid glycoprotein. | Pharmaceutical research 20040901 |
| Regulation of Na+/Mg2+ antiport in rat erythrocytes. | Biochimica et biophysica acta 20040830 |
| Death-associated protein 3 localizes to the mitochondria and is involved in the process of mitochondrial fragmentation during cell death. | The Journal of biological chemistry 20040827 |
| PKC412 induces apoptosis through a caspase-dependent mechanism in human keloid-derived fibroblasts. | European journal of pharmacology 20040823 |
| Simultaneous imaging of initiator/effector caspase activity and mitochondrial membrane potential during cell death in living HeLa cells. | Biochimica et biophysica acta 20040823 |
| Apoptosis-inducing factor determines the chemoresistance of non-small-cell lung carcinomas. | Oncogene 20040819 |
| Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion. | The EMBO journal 20040818 |
| Gene- and cell-type-specific effects of signal transduction cascades on metal-regulated gene transcription appear to be independent of changes in the phosphorylation of metal-response-element-binding transcription factor-1. | The Biochemical journal 20040815 |
| G-protein-coupled receptor regulation of P2X1 receptors does not involve direct channel phosphorylation. | The Biochemical journal 20040815 |
| Involvement of MAP-kinase, PI3-kinase and EGF-receptor in the stimulatory effect of Neurotensin on DNA synthesis in PC3 cells. | Regulatory peptides 20040815 |
| Muscarinic modulation of erg potassium current. | The Journal of physiology 20040815 |
| Genetic diversity in chlorella viruses flanking kcv, a gene that encodes a potassium ion channel protein. | Virology 20040815 |
| The C-type lectin homologue gene (EP153R) of African swine fever virus inhibits apoptosis both in virus infection and in heterologous expression. | Virology 20040815 |
| Effects of alpha1-adrenergic stimulation on normal and hypertrophied mouse hearts. Relation to caveolin-3 expression. | Cardiovascular research 20040815 |
| Caspase-2 can function upstream of bid cleavage in the TRAIL apoptosis pathway. | The Journal of biological chemistry 20040813 |
| Bcl-2 is a key factor for cardiac fibroblast resistance to programmed cell death. | The Journal of biological chemistry 20040813 |
| A caspase-8-independent signaling pathway activated by Fas ligation leads to exposure of the Bak N terminus. | The Journal of biological chemistry 20040806 |
| Synthesis and structure-activity relationships of novel IKK-beta inhibitors. Part 2: Improvement of in vitro activity. | Bioorganic & medicinal chemistry letters 20040802 |
| Drug-resistant breast carcinoma (MCF-7) cells are paradoxically sensitive to apoptosis. | Journal of cellular physiology 20040801 |
| EGF-Like domain of tenascin-C is proapoptotic for cultured smooth muscle cells. | Arteriosclerosis, thrombosis, and vascular biology 20040801 |
| The immune modulator FTY720 targets sphingosine-kinase-dependent migration of human monocytes in response to amyloid beta-protein and its precursor. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040801 |
| Commonly used antibiotics induce expression of Hsp 27 and Hsp 60 and protect human lymphocytes from apoptosis. | International immunopharmacology 20040801 |
| UCN-01 alters phosphorylation of Akt and GSK3beta and induces apoptosis in six independent human neuroblastoma cell lines. | Journal of neurochemistry 20040801 |
| Voltage-gated K+ current: a marker for apoptosis in differentiating neuronal progenitor cells? | The European journal of neuroscience 20040801 |
| Up-regulation of Na(+)-Ca2+ exchange activity by interferon-gamma in cultured rat microglia. | Journal of neurochemistry 20040801 |
| Superior activity of the combination of histone deacetylase inhibitor LAQ824 and the FLT-3 kinase inhibitor PKC412 against human acute myelogenous leukemia cells with mutant FLT-3. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040801 |
| In vitro combination treatment with perifosine and UCN-01 demonstrates synergism against prostate (PC-3) and lung (A549) epithelial adenocarcinoma cell lines. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040801 |
| Endothelial cells protect against lipopolysaccharide-induced caspase-3-mediated pericyte apoptosis in a coculture system. | Surgery 20040801 |
| Bioluminescence-based ATP assays using a charge-coupled device imaging system. | BioTechniques 20040801 |
| Modulation of presynaptic activity by phosphorylation in cultured rat spinal dorsal horn neurons. | The journal of pain : official journal of the American Pain Society 20040801 |
| The acceptor availability at photosystem I and ABA control nuclear expression of 2-Cys peroxiredoxin-A in Arabidopsis thaliana. | Plant & cell physiology 20040801 |
| Brain-derived neurotrophic factor facilitates glutamate and inhibits GABA release from hippocampal synaptosomes through different mechanisms. | Brain research 20040730 |
| Up-regulation of human beta-defensin 2 by interleukin-1beta in A549 cells: involvement of PI3K, PKC, p38 MAPK, JNK, and NF-kappaB. | Biochemical and biophysical research communications 20040730 |
| Staurosporine restores GTPgammaS induced block of rapid endocytosis in chromaffin cells. | FEBS letters 20040730 |
| Substituted 3-imidazo[1,2-a]pyridin-3-yl- 4-(1,2,3,4-tetrahydro-[1,4]diazepino-[6,7,1-hi]indol-7-yl)pyrrole-2,5-diones as highly selective and potent inhibitors of glycogen synthase kinase-3. | Journal of medicinal chemistry 20040729 |
| Evidence for colorectal cancer cell specificity of aspirin effects on NF kappa B signalling and apoptosis. | British journal of cancer 20040719 |
| Cholinergic modulation of baker's yeast cell phagocytosis by rat astrocytes. | Neuroscience letters 20040715 |
| Entrapment of Src protein tyrosine kinase in sugar-modified silica. | Analytical chemistry 20040715 |
| Inhibition of platelet adherence to mononuclear cells by alpha-tocopherol: role of P-selectin. | Circulation 20040713 |
| BOK and NOXA are essential mediators of p53-dependent apoptosis. | The Journal of biological chemistry 20040702 |
| PKC-independent inhibition of neuronal nicotinic acetylcholine receptors by diacylglycerol. | Brain research 20040702 |
| Contribution of caveolin-1 alpha and Akt to TNF-alpha-induced cell death. | American journal of physiology. Lung cellular and molecular physiology 20040701 |
| Identification of caspase-independent apoptosis in epithelial and cancer cells. | The Journal of pharmacology and experimental therapeutics 20040701 |
| Leishmania major-mediated prevention of programmed cell death induction in infected macrophages is associated with the repression of mitochondrial release of cytochrome c. | Journal of leukocyte biology 20040701 |
| Induction of cell stress through gene transfer of an engineered heat shock transcription factor enhances tumor immunogenicity. | Gene therapy 20040701 |
| Rac-induced increase of phosphorylation of myosin regulatory light chain in HeLa cells. | Cell motility and the cytoskeleton 20040701 |
| Nicotine exerts a permissive role on NMDA receptor function in hippocampal noradrenergic terminals. | Neuropharmacology 20040701 |
| Activation of deoxycytidine kinase by protein kinase inhibitors and okadaic acid in leukemic cells. | Biochemical pharmacology 20040701 |
| Evidence for contribution of vascular NAD(P)H oxidase to increased oxidative stress in animal models of diabetes and obesity. | Free radical biology & medicine 20040701 |
| Characterization of 4-O-methyl-ascochlorin-induced apoptosis in comparison with typical apoptotic inducers in human leukemia cell lines. | Apoptosis : an international journal on programmed cell death 20040701 |
| LPS-induced apoptosis is dependent upon mitochondrial dysfunction. | Apoptosis : an international journal on programmed cell death 20040701 |
| Intracellular signalling and cytoskeletal rearrangement involved in Yersinia pestis plasminogen activator (Pla) mediated HeLa cell invasion. | Microbial pathogenesis 20040701 |
| When cells die II: a comprehensive evaluation of apoptosis and programmed cell death. | Cell death and differentiation 20040701 |
| Interactions between NMDA receptors and mGlu5 receptors expressed in HEK293 cells. | British journal of pharmacology 20040701 |
| Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system. | The American journal of pathology 20040701 |
| Time to disease progression to evaluate a novel protein kinase C inhibitor, UCN-01, in renal cell carcinoma. | Cancer 20040701 |
| Maternally-inherited Leigh syndrome-related mutations bolster mitochondrial-mediated apoptosis. | Journal of neurochemistry 20040701 |
| Classification of brassinosteroid-regulated genes based on expression profiles in bri1 and in response to a protein kinase inhibitor, staurosporin. | Bioscience, biotechnology, and biochemistry 20040701 |
| [Mode of action and molecular target of ECH, a specific inhibitor of death receptor-dependent apoptosis]. | Nihon rinsho. Japanese journal of clinical medicine 20040701 |
| PKC downstream of Pl3-kinase regulates peroxynitrite formation for Nrf2-mediated GSTA2 induction. | Archives of pharmacal research 20040701 |
| Circadian rhythm of glucose uptake in cultures of skeletal muscle cells and adipocytes in Wistar-Kyoto, Wistar, Goto-Kakizaki, and spontaneously hypertensive rats. | Chronobiology international 20040701 |
| PACAP maintains cell cycling and inhibits apoptosis in chick neuroblasts. | Molecular and cellular endocrinology 20040630 |
| Rapid degradation of Cdt1 upon UV-induced DNA damage is mediated by SCFSkp2 complex. | The Journal of biological chemistry 20040625 |
| High glucose down-regulates intercellular communication in retinal endothelial cells by enhancing degradation of connexin 43 by a proteasome-dependent mechanism. | The Journal of biological chemistry 20040625 |
| Platelet 12-lipoxygenase activation via glycoprotein VI: involvement of multiple signaling pathways in agonist control of H(P)ETE synthesis. | Circulation research 20040625 |
| The NHE1 Na+/H+ exchanger recruits ezrin/radixin/moesin proteins to regulate Akt-dependent cell survival. | The Journal of biological chemistry 20040618 |
| Persistent activation of the Akt pathway in head and neck squamous cell carcinoma: a potential target for UCN-01. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040615 |
| Mcl-1 is a novel therapeutic target for human sarcoma: synergistic inhibition of human sarcoma xenotransplants by a combination of mcl-1 antisense oligonucleotides with low-dose cyclophosphamide. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040615 |
| Autophagosome-like vacuole formation in Huntington's disease lymphoblasts. | Neuroreport 20040607 |
| Tim50, a component of the mitochondrial translocator, regulates mitochondrial integrity and cell death. | The Journal of biological chemistry 20040604 |
| Nerve growth factor and substance P regulation in nasal sensory neurons after toluene diisocyanate exposure. | American journal of respiratory cell and molecular biology 20040601 |
| Protease-activated receptor-2-mediated inhibition for Ca2+ response to lipopolysaccharide in Guinea pig tracheal epithelial cells. | American journal of respiratory cell and molecular biology 20040601 |
| Apoptosis induced by staurosporine in ECV304 cells requires cell shrinkage and upregulation of Cl- conductance. | Cell death and differentiation 20040601 |
| Physical and functional interaction of growth hormone and insulin-like growth factor-I signaling elements. | Molecular endocrinology (Baltimore, Md.) 20040601 |
| Effects of chloride and potassium channel blockers on apoptotic cell shrinkage and apoptosis in cortical neurons. | Pflugers Archiv : European journal of physiology 20040601 |
| Neuroprotective properties of Bcl-w in Alzheimer disease. | Journal of neurochemistry 20040601 |
| In vivo induction of endothelial apoptosis leads to vessel thrombosis and endothelial denudation: a clue to the understanding of the mechanisms of thrombotic plaque erosion. | Circulation 20040601 |
| Monitoring caspase activity in living cells using fluorescent proteins and flow cytometry. | The American journal of pathology 20040601 |
| Abrogation of Chk1-mediated S/G2 checkpoint by UCN-01 enhances ara-C-induced cytotoxicity in human colon cancer cells. | Acta pharmacologica Sinica 20040601 |
| Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase. | Genes & development 20040601 |
| Interleukin-4 stimulates papillary thyroid cancer cell survival: implications in patients with thyroid cancer and concomitant Graves' disease. | The Journal of clinical endocrinology and metabolism 20040601 |
| Red blood cells inhibit proliferation and stimulate apoptosis in human lung fibroblasts in vitro. | Scandinavian journal of immunology 20040601 |
| Transfection of 2,6 and 2,3-sialyltransferase genes and GlcNAc-transferase genes into human glioma cell line U-373 MG affects glycoconjugate expression and enhances cell death. | Journal of neurochemistry 20040601 |
| MGLuR5 activation reduces beta-amyloid-induced cell death in primary neuronal cultures and attenuates translocation of cytochrome c and apoptosis-inducing factor. | Journal of neurochemistry 20040601 |
| Selenium has a protective role in caspase-3-dependent apoptosis induced by H2O2 in primary cultured pig thyrocytes. | European journal of endocrinology 20040601 |
| Development of a fluorescence polarization bead-based coupled assay to target different activity/conformation states of a protein kinase. | Journal of biomolecular screening 20040601 |
| The tyrosine phosphatase inhibitor orthovanadate mimics NGF-induced neuroprotective signaling in rat hippocampal neurons. | Neurochemistry international 20040601 |
| Apoptosis of hippocampal neurons in organotypic slice culture models: direct effect of bacteria revisited. | Journal of neuropathology and experimental neurology 20040601 |
| Apoptosis is not an invariable component of in vitro models of cortical cerebral ischaemia. | Cell research 20040601 |
| Flow cytometric measurement of neutrophil respiratory burst in whole bovine blood using live Staphylococcus aureus. | Journal of immunological methods 20040601 |
| The protein kinase C inhibitor bisindolyl maleimide 2 binds with reversed orientations to different conformations of protein kinase A. | The Journal of biological chemistry 20040528 |
| Nicotine induces multi-site phosphorylation of Bad in association with suppression of apoptosis. | The Journal of biological chemistry 20040528 |
| Brain-derived neurotrophic factor and tyrosine kinase receptor B involvement in amygdala-dependent fear conditioning. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040519 |
| Human alpha1D-adrenoceptor phosphorylation and desensitization. | Biochemical pharmacology 20040515 |
| Anti-proliferation effect of 3-amino-2-imino-3,4-dihydro-2H-1,3-benzothiazin-4-one (BJ-601) on human vascular endothelial cells: G0/G1 p21-associated cell cycle arrest. | Biochemical pharmacology 20040515 |
| UCN-01-induced cell cycle arrest requires the transcriptional induction of p21(waf1/cip1) by activation of mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway. | Cancer research 20040515 |
| Cotreatment with 17-allylamino-demethoxygeldanamycin and FLT-3 kinase inhibitor PKC412 is highly effective against human acute myelogenous leukemia cells with mutant FLT-3. | Cancer research 20040515 |
| Myoblast survival enhancement and transplantation success improvement by heat-shock treatment in mdx mice. | Transplantation 20040515 |
| The sphingolipid pathway regulates Pkc1 through the formation of diacylglycerol in Cryptococcus neoformans. | The Journal of biological chemistry 20040514 |
| Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria. | The Journal of biological chemistry 20040507 |
| Towards configurationally stable bisindolylmaleimide cyclophanes: potential tools for investigating protein kinase function. | Chemical communications (Cambridge, England) 20040507 |
| Brain-derived neurotrophic factor-elicited or sciatic ligation-associated phosphorylation of cyclic AMP response element binding protein in the rat spinal dorsal horn is reduced by block of tyrosine kinase receptors. | Neuroscience letters 20040506 |
| Role of protein kinase C and NF-kappaB in proteolysis-inducing factor-induced proteasome expression in C(2)C(12) myotubes. | British journal of cancer 20040504 |
| Aurora-A is a critical regulator of microtubule assembly and nuclear activity in mouse oocytes, fertilized eggs, and early embryos. | Biology of reproduction 20040501 |
| Localization of VEGFR-2 and PLD2 in endothelial caveolae is involved in VEGF-induced phosphorylation of MEK and ERK. | American journal of physiology. Heart and circulatory physiology 20040501 |
| Cytochrome P-450 metabolites in endothelin-stimulated cardiac hormone secretion. | American journal of physiology. Regulatory, integrative and comparative physiology 20040501 |
| Genotoxic and antiapoptotic effect of nicotine on human gingival fibroblasts. | Toxicological sciences : an official journal of the Society of Toxicology 20040501 |
| Bcl2-low-expressing MCF7 cells undergo necrosis rather than apoptosis upon staurosporine treatment. | The Biochemical journal 20040501 |
| Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis. | Cell death and differentiation 20040501 |
| nitric oxide triggers the phosphatidylinositol 3-kinase/Akt survival pathway in insulin-producing RINm5F cells by arousing Src to activate insulin receptor substrate-1. | Endocrinology 20040501 |
| Drug-induced increase of carcinoembryonic antigen expression in cancer cells. | Pharmacological research 20040501 |
| Epidermal growth factor inhibits 14C-alpha-methyl-D-glucopyranoside uptake in renal proximal tubule cells: involvement of PLC/PKC, p44/42 MAPK, and cPLA2. | Journal of cellular physiology 20040501 |
| Combination therapy in ischemic stroke: synergistic neuroprotective effects of memantine and clenbuterol. | Stroke 20040501 |
| Metabolism of UCN-01 in isolated perfused rat liver: role of Mrp2 in the biliary excretion of glucuronides. | Oncology reports 20040501 |
| Exercise induces BDNF and synapsin I to specific hippocampal subfields. | Journal of neuroscience research 20040501 |
| Phosphatidylserine efflux and intercellular fusion in a BeWo model of human villous cytotrophoblast. | Placenta 20040501 |
| Force-independent expression of c-fos mRNA by endothelin-1 in rat intact small mesenteric arteries. | Acta physiologica Scandinavica 20040501 |
| Differential regulation of X-chromosome-linked inhibitor of apoptosis protein (XIAP) and caspase-3 by NMDA in developing hippocampal neurons; involvement of the mitochondrial pathway in NMDA-mediated neuronal survival. | Experimental cell research 20040501 |
| The antiapoptotic effect of guanosine is mediated by the activation of the PI 3-kinase/AKT/PKB pathway in cultured rat astrocytes. | Glia 20040501 |
| The value of DNA methylation analysis in basic, initial toxicity assessments. | Toxicological sciences : an official journal of the Society of Toxicology 20040501 |
| Transcription factor Ets-1 mediates ischemia- and vascular endothelial growth factor-dependent retinal neovascularization. | The American journal of pathology 20040501 |
| Induction of Mycobacterium avium growth restriction and inhibition of phagosome-endosome interactions during macrophage activation and apoptosis induction by picolinic acid plus IFNgamma. | Microbiology (Reading, England) 20040501 |
| Differential regulation of the mitochondrial and death receptor pathways in neural stem cells. | The European journal of neuroscience 20040501 |
| Initial stages of low-temperature induction of cabbage cold shock protein gene csp5. | Biochemistry. Biokhimiia 20040501 |
| Mitochondrial translocation of p53 and mitochondrial membrane potential (Delta Psi m) dissipation are early events in staurosporine-induced apoptosis of wild type and mutated p53 epithelial cells. | Apoptosis : an international journal on programmed cell death 20040501 |
| Crystal structures of interleukin-2 tyrosine kinase and their implications for the design of selective inhibitors. | The Journal of biological chemistry 20040430 |
| Clathrin-mediated endocytosis of Na+,K+-ATPase in response to parathyroid hormone requires ERK-dependent phosphorylation of Ser-11 within the alpha1-subunit. | The Journal of biological chemistry 20040423 |
| Effect of exogenous neurotrophins on Trk receptor phosphorylation, cell proliferation, and neurotrophin secretion by cells isolated from the human lamina cribrosa. | Molecular vision 20040419 |
| Increased immunogenicity of colon cancer cells by selective depletion of cytochrome C. | Cancer research 20040415 |
| Cyclic AMP activation of the extracellular signal-regulated kinases 1 and 2: implications for intestinal cell survival through the transient inhibition of apoptosis. | The Journal of biological chemistry 20040409 |
| The mitochondrial ARTS protein promotes apoptosis through targeting XIAP. | The EMBO journal 20040407 |
| [Transforming growth factor beta 1 modulates connective tissue growth factor expression via Smad2 signaling pathway in podocyte in vitro]. | Zhonghua yi xue za zhi 20040402 |
| Signaling cascade of ANG II-induced inhibition of alpha-MG uptake in renal proximal tubule cells. | American journal of physiology. Renal physiology 20040401 |
| Interruption of the NF-kappaB pathway by Bay 11-7082 promotes UCN-01-mediated mitochondrial dysfunction and apoptosis in human multiple myeloma cells. | Blood 20040401 |
| Bcl-2 overexpression prevents 99mTc-MIBI uptake in breast cancer cell lines. | European journal of nuclear medicine and molecular imaging 20040401 |
| Alterations in PKC signaling underlie enhanced myogenic tone in exercise-trained porcine coronary resistance arteries. | Journal of applied physiology (Bethesda, Md. : 1985) 20040401 |
| A phase I trial of daily oral 4'- N -benzoyl-staurosporine in combination with protracted continuous infusion 5-fluorouracil in patients with advanced solid malignancies. | Investigational new drugs 20040401 |
| Protein phosphatase 1 and an opposing protein kinase regulate steady-state L-type Ca2+ current in mouse cardiac myocytes. | The Journal of physiology 20040401 |
| Dopamine neurons release transmitter via a flickering fusion pore. | Nature neuroscience 20040401 |
| Modulation of trigeminal sensory neuron activity by the dual cannabinoid-vanilloid agonists anandamide, N-arachidonoyl-dopamine and arachidonyl-2-chloroethylamide. | British journal of pharmacology 20040401 |
| The insecticidal toxin Makes caterpillars floppy (Mcf) promotes apoptosis in mammalian cells. | Cellular microbiology 20040401 |
| Staurosporine-induced apoptosis in Chang liver cells is associated with down-regulation of Bcl-2 and Bcl-XL. | International journal of molecular medicine 20040401 |
| Crystallization and preliminary X-ray analysis of two inhibitor complexes of the catalytic domain of death-associated protein kinase. | Acta crystallographica. Section D, Biological crystallography 20040401 |
| PknH, a transmembrane Hank's type serine/threonine kinase from Mycobacterium tuberculosis is differentially expressed under stress conditions. | FEMS microbiology letters 20040401 |
| Three members of the connective tissue growth factor family CCN are differentially regulated by mechanical stress. | Biochimica et biophysica acta 20040401 |
| Raising intracellular calcium attenuates neuronal apoptosis triggered by staurosporine or oxygen-glucose deprivation in the presence of glutamate receptor blockade. | Neurobiology of disease 20040401 |
| Cadmium induces both pyruvate kinase and Na+/H+ exchanger activity through protein kinase C mediated signal transduction, in isolated digestive gland cells of Mytilus galloprovincialis (L.). | The Journal of experimental biology 20040401 |
| Deletion mutant of FGFR4 induces onion-like membrane structures in the nucleus. | Journal of cell science 20040401 |
| Neural stem cells and cell death. | Toxicology letters 20040401 |
| Mechanisms of cell death in Alzheimer's disease: role of presenilins. | Journal of Alzheimer's disease : JAD 20040401 |
| Mitochondrial DNA mutation and depletion increase the susceptibility of human cells to apoptosis. | Annals of the New York Academy of Sciences 20040401 |
| Resistance of rho(0) cells against apoptosis. | Annals of the New York Academy of Sciences 20040401 |
| Initiation of apoptotic signal by the peroxidation of cardiolipin of mitochondria. | Annals of the New York Academy of Sciences 20040401 |
| Sensitive genetic biomarkers for determining apoptosis in the brown bullhead (Ameiurus nebulosus). | Gene 20040331 |
| Ras GTPase-activating protein binds to Akt and is required for its activation. | The Journal of biological chemistry 20040326 |
| mRNA is an endogenous ligand for Toll-like receptor 3. | The Journal of biological chemistry 20040326 |
| Effect of Ginkgo biloba (EGb 761) on staurosporine-induced neuronal death and caspase activity in cortical cultured neurons. | Brain research 20040326 |
| Golgi fragmentation during Fas-mediated apoptosis is associated with the rapid loss of GM130. | Biochemical and biophysical research communications 20040326 |
| Activation of adenosine A2A receptor facilitates brain-derived neurotrophic factor modulation of synaptic transmission in hippocampal slices. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040324 |
| Aven and Bcl-xL enhance protection against apoptosis for mammalian cells exposed to various culture conditions. | Biotechnology and bioengineering 20040320 |
| Developmental cell death in dictyostelium does not require paracaspase. | The Journal of biological chemistry 20040319 |
| Mutations in the tyrosine kinase domain of FLT3 define a new molecular mechanism of acquired drug resistance to PTK inhibitors in FLT3-ITD-transformed hematopoietic cells. | Blood 20040315 |
| Protein flexibility in ligand docking and virtual screening to protein kinases. | Journal of molecular biology 20040312 |
| Hypoxia selection of death-resistant cells. A role for Bcl-X(L). | The Journal of biological chemistry 20040305 |
| Oligogalacturonide signal transduction, induction of defense-related responses and protection of grapevine against Botrytis cinerea. | Planta 20040301 |
| Exocytosis of a complement component C3-like protein by tunicate hemocytes. | Developmental and comparative immunology 20040301 |
| Effect of K-252a and abscisic acid on the efflux of citrate from soybean roots. | Journal of experimental botany 20040301 |
| Caldesmon phosphorylation is catalyzed by two kinases in permeabilized and intact vascular smooth muscle. | Journal of cellular physiology 20040301 |
| Glucagon-like peptide-1 regulates proliferation and apoptosis via activation of protein kinase B in pancreatic INS-1 beta cells. | Diabetologia 20040301 |
| Phosphorylation and 14-3-3 binding of Arabidopsis 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. | The Plant journal : for cell and molecular biology 20040301 |
| The cytoplasmic domain of CEACAM1-L controls its lateral localization and the organization of desmosomes in polarized epithelial cells. | Journal of cell science 20040301 |
| Differential role of Janus family kinases (JAKs) in interferon-gamma-induced lung epithelial ICAM-1 expression: involving protein interactions between JAKs, phospholipase Cgamma, c-Src, and STAT1. | Molecular pharmacology 20040301 |
| Neurotrophins improve neuromuscular transmission in the adult rat diaphragm. | Muscle & nerve 20040301 |
| Reduction of diabetic macular edema by oral administration of the kinase inhibitor PKC412. | Investigative ophthalmology & visual science 20040301 |
| Anti-apoptotic activity of the glutathione peroxidase homologue encoded by HIV-1. | Apoptosis : an international journal on programmed cell death 20040301 |
| Impairment of death-inducing signalling complex formation in CD95-resistant human primary lymphoma B cells. | British journal of haematology 20040301 |
| HSP27 but not HSP70 has a potent protective effect against alpha-synuclein-induced cell death in mammalian neuronal cells. | Journal of neurochemistry 20040301 |
| An aurora kinase is essential for flagellar disassembly in Chlamydomonas. | Developmental cell 20040301 |
| Neurogenic and intact or apoptotic non-neurogenic areas of adult brain release diffusible molecules that differentially modulate the development of subventricular zone cell cultures. | The European journal of neuroscience 20040301 |
| K252a, a high-affinity nerve growth factor receptor blocker, improves psoriasis: an in vivo study using the severe combined immunodeficient mouse-human skin model. | The Journal of investigative dermatology 20040301 |
| Dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) inhibit the apoptosis in human peripheral blood lymphocytes. | The Journal of steroid biochemistry and molecular biology 20040301 |
| Mechanisms of resistance to the cytotoxic effects of oxysterols in human leukemic cells. | The Journal of steroid biochemistry and molecular biology 20040301 |
| On the evolution of erythrocyte programmed cell death: apoptosis of Rana esculenta nucleated red blood cells involves cysteine proteinase activation and mitochondrion permeabilization. | Biochimie 20040301 |
| A novel method for imaging apoptosis using a caspase-1 near-infrared fluorescent probe. | Neoplasia (New York, N.Y.) 20040301 |
| Externalization of phosphatidylserine during apoptosis does not specifically require either isoform of phosphatidylserine synthase. | Biochimica et biophysica acta 20040227 |
| NGF activation of TrkA decreases N-myc expression via MAPK path leading to a decrease in neuroblastoma cell number. | Oncogene 20040226 |
| AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis. | Oncogene 20040226 |
| Mechanosensitivity of GIRK channels is mediated by protein kinase C-dependent channel-phosphatidylinositol 4,5-bisphosphate interaction. | The Journal of biological chemistry 20040220 |
| Ruthenium complexes as protein kinase inhibitors. | Organic letters 20040219 |
| HSulf-1 modulates HGF-mediated tumor cell invasion and signaling in head and neck squamous carcinoma. | Oncogene 20040219 |
| Cell cycle activation linked to neuronal cell death initiated by DNA damage. | Neuron 20040219 |
| Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3. | Neuron 20040219 |
| Pheophorbide a is a specific probe for ABCG2 function and inhibition. | Cancer research 20040215 |
| Cholinergic regulation of Na+-K+-ATPase activity in rat parotid gland: changes after castration. | European journal of pharmacology 20040213 |
| A Ca(2+)-dependent protein kinase with characteristics of protein kinase C in leaves and mesophyll cell protoplasts from Digitaria sanguinalis: possible involvement in the C(4)-phosphoenolpyruvate carboxylase phosphorylation cascade. | Biochemical and biophysical research communications 20040206 |
| Peroxovanadate induces alpha 1B-adrenoceptor phosphorylation and association with protein kinase C. | European journal of pharmacology 20040206 |
| Neuroprotection by cyclosporin A following transient brain ischemia correlates with the inhibition of the early efflux of cytochrome C to cytoplasm. | Brain research. Molecular brain research 20040205 |
| Rapid annexin-V labeling in synaptosomes. | Neurochemistry international 20040201 |
| Glycogen synthase kinase-3 regulates cytoskeleton and translocation of Rac1 in long cellular extensions of human keratinocytes. | Experimental cell research 20040201 |
| Nuclear bodies and compartmentalization of pre-mRNA splicing factors in higher plants. | Chromosoma 20040201 |
| Novel radiosensitizers for locally advanced epithelial tumors: inhibition of the PI3K/Akt survival pathway in tumor cells and in tumor-associated endothelial cells as a novel treatment strategy? | International journal of radiation oncology, biology, physics 20040201 |
| Death of cortical and striatal neurons induced by mitochondrial defect involves differential molecular mechanisms. | Neurobiology of disease 20040201 |
| Phase I study of PKC412 (N-benzoyl-staurosporine), a novel oral protein kinase C inhibitor, combined with gemcitabine and cisplatin in patients with non-small-cell lung cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20040201 |
| Staurosporine induces apoptosis of melanoma by both caspase-dependent and -independent apoptotic pathways. | Molecular cancer therapeutics 20040201 |
| Arabidopsis RAV1 is down-regulated by brassinosteroid and may act as a negative regulator during plant development. | Cell research 20040201 |
| Effect of a Korean traditional formulation, Hwaotang, on superoxide generation in human neutrophils, platelet aggregation in human blood, and nitric oxide, prostaglandin E2 production and paw oedema induced by carrageenan in mice. | Immunopharmacology and immunotoxicology 20040201 |
| Analysis of caspase-3, caspase-8 and caspase-9 enzymatic activities in mouse oocytes and zygotes. | Zygote (Cambridge, England) 20040201 |
| Signaling pathways of the F11 receptor (F11R; a.k.a. JAM-1, JAM-A) in human platelets: F11R dimerization, phosphorylation and complex formation with the integrin GPIIIa. | Journal of receptor and signal transduction research 20040201 |
| Characterization of the protein kinase activity of TRPM7/ChaK1, a protein kinase fused to the transient receptor potential ion channel. | The Journal of biological chemistry 20040130 |
| Lysophosphatidylcholine is a regulator of tyrosine kinase activity and intracellular Ca(2+) level in Jurkat T cell line. | Immunology letters 20040130 |
| Coupling of caspase-9 to Apaf1 in response to loss of pRb or cytotoxic drugs is cell-type-specific. | The EMBO journal 20040128 |
| Statins potentiate caspase-3 activity in immortalized murine neurons. | Neuroscience letters 20040123 |
| Celecoxib simulates respiratory burst through pertussis toxin-sensitive G-protein, a possible signal for beta 2-integrin expression on human neutrophils. | European journal of pharmacology 20040119 |
| In self-defence: hexokinase promotes voltage-dependent anion channel closure and prevents mitochondria-mediated apoptotic cell death. | The Biochemical journal 20040115 |
| Effect of vascular endothelial growth factor and epidermal growth factor on iatrogenic apoptosis in human endothelial cells. | Biochemical pharmacology 20040115 |
| Effect of staurosporine on cycle of human gastric cancer cells. | World journal of gastroenterology 20040115 |
| Caspase-7 gene disruption reveals an involvement of the enzyme during the early stages of apoptosis. | The Journal of biological chemistry 20040109 |
| Primary cultured neurons devoid of cellular prion display lower responsiveness to staurosporine through the control of p53 at both transcriptional and post-transcriptional levels. | The Journal of biological chemistry 20040102 |
| Interleukin-18 is regulated by G protein pathways and protein kinase signals in human fibroblasts. | Rheumatology international 20040101 |
| Mutual dependence of VIP/PACAP and CCK receptor signaling for a physiological role in duck exocrine pancreatic secretion. | American journal of physiology. Regulatory, integrative and comparative physiology 20040101 |
| c-Myc-deficient B lymphocytes are resistant to spontaneous and induced cell death. | Cell death and differentiation 20040101 |
| Regulation of sodium-dicarboxylate cotransporter-3 from winter flounder kidney by protein kinase C. | American journal of physiology. Renal physiology 20040101 |
| Further evidence that the tyrosine phosphorylation of glycogen synthase kinase-3 (GSK3) in mammalian cells is an autophosphorylation event. | The Biochemical journal 20040101 |
| Opposing effect of angiopoietin-1 on VEGF-mediated disruption of endothelial cell-cell interactions requires activation of PKC beta. | Journal of cellular physiology 20040101 |
| Ischemia-induced phosphorylation of phospholemman directly activates rat cardiac Na/K-ATPase. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040101 |
| Contractile forces generated by articular chondrocytes in collagen-glycosaminoglycan matrices. | Biomaterials 20040101 |
| Parkin is recruited into aggresomes in a stress-specific manner: over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival. | Human molecular genetics 20040101 |
| Models of breast cancer: is merging human and animal models the future? | Breast cancer research : BCR 20040101 |
| Regulation of sphingomyelinases in cells of the oligodendrocyte lineage. | Journal of neuroscience research 20040101 |
| Interferon-gamma induces apoptosis of lens alphaTN4-1 cells and proteasome inhibition has an antiapoptotic effect. | Investigative ophthalmology & visual science 20040101 |
| Parathyroid hormone inhibits the expression of membrane-type matrix metalloproteinase-1 (MT1-MMP) in osteoblast-like MG-63 cells. | Journal of bone and mineral metabolism 20040101 |
| Effects of estrone on N-methyl-D-aspartic acid- and staurosporine-induced changes in caspase-3-like protease activity and lactate dehydrogenase-release: time- and tissue-dependent effects in neuronal primary cultures. | Neuroscience 20040101 |
| hSulf1 Sulfatase promotes apoptosis of hepatocellular cancer cells by decreasing heparin-binding growth factor signaling. | Gastroenterology 20040101 |
| Cell-cycle targeted therapies. | The Lancet. Oncology 20040101 |
| Immortalization of mouse myogenic cells can occur without loss of p16INK4a, p19ARF, or p53 and is accelerated by inactivation of Bax. | BMC cell biology 20040101 |
| Pyruvate limits zinc-induced rat oligodendrocyte progenitor cell death. | The European journal of neuroscience 20040101 |
| Augmented 18F-FDG uptake in activated monocytes occurs during the priming process and involves tyrosine kinases and protein kinase C. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20040101 |
| Neuroprotection by transforming growth factor-beta1 involves activation of nuclear factor-kappaB through phosphatidylinositol-3-OH kinase/Akt and mitogen-activated protein kinase-extracellular-signal regulated kinase1,2 signaling pathways. | Neuroscience 20040101 |
| Ionizing radiation sensitizes bone cells to apoptosis. | Bone 20040101 |
| Inhibition of apoptosis by a Bombyx mori gene. | Biotechnology progress 20040101 |
| Neuronal gelsolin prevents apoptosis by enhancing actin depolymerization. | Molecular and cellular neurosciences 20040101 |
| Role of ionic fluxes in the apoptotic cell death of cultured cerebellar granule neurons. | Neurochemical research 20040101 |
| A flow cytometric assay for global estimation of tyrosine phosphorylation associated with capacitation of spermatozoa from two marsupial species, the tammar wallaby (Macropus eugenii) and the brushtail possum (Trichosurus vulpecula). | Reproduction (Cambridge, England) 20040101 |
| Effects of 'second-hand' smoke on structure and function of fibroblasts, cells that are critical for tissue repair and remodeling. | BMC cell biology 20040101 |
| Xanthurenic acid translocates proapoptotic Bcl-2 family proteins into mitochondria and impairs mitochondrial function. | BMC cell biology 20040101 |
| Upregulation of survivin in G2/M cells and inhibition of caspase 9 activity enhances resistance in staurosporine-induced apoptosis. | Neoplasia (New York, N.Y.) 20040101 |
| Infection with Campylobacter jejuni induces tyrosine-phosphorylated proteins into INT-407 cells. | Microbiology and immunology 20040101 |
| Involvement of protein kinases on the process of erythrophagocytis by Entamoeba histolytica. | Cell biology international 20040101 |
| [Dynamics of some postreplication DNA repair proteins in carcinogen-damaged mammalian cells]. | Tsitologiia 20040101 |
| Lithium facilitates apoptotic signaling induced by activation of the Fas death domain-containing receptor. | BMC neuroscience 20040101 |
| Anti-apoptotic effect of atorvastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, on cardiac myocytes through protein kinase C activation. | Clinical and experimental pharmacology & physiology 20040101 |
| Brain-derived neurotrophic factor increases inhibitory synapses, revealed in solitary neurons cultured from rat visual cortex. | Neuroscience 20040101 |
| Activation of extracellular signal-regulated protein kinase in the dorsal root ganglion following inflammation near the nerve cell body. | Neuroscience 20040101 |
| Inhibition of mitochondrial bioenergetics: the effects on structure of mitochondria in the cell and on apoptosis. | Acta biochimica Polonica 20040101 |
| Release of DNA from dead and dying lymphocyte and monocyte cell lines in vitro. | Scandinavian journal of immunology 20040101 |
| Detection of apoptosis in cartilage in situ and in isolated chondrocytes. | Methods in molecular medicine 20040101 |
| A traditional herbal medicine, rikkunshi-to (TJ-43), prevents intracellular signaling disorders in gastric smooth muscle of diabetic rats. | The American journal of Chinese medicine 20040101 |
| Synovial fibroblasts from rheumatoid arthritis patients differ in their regulation of IL-16 gene activity in comparison to osteoarthritis fibroblasts. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20040101 |
| Effect of epinephrine on alpha-methyl-D-glucopyranoside uptake in renal proximal tubule cells. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20040101 |
| Opposite role of Bax and BCL-2 in the anti-tumoral responses of the immune system. | BMC cancer 20040101 |
| Effects of protein kinase C on M-phase promoting factor in early development of fertilized mouse eggs. | Cell biochemistry and function 20040101 |
| The phosphatidylserine receptor has essential functions during embryogenesis but not in apoptotic cell removal. | Journal of biology 20040101 |
| Study of programmed cell death in bovine herpesvirus 1 infected MDBK cells and the possible role of nitric oxide in this process. | Acta veterinaria Hungarica 20040101 |
| Characterization of dual specificity protein kinase from maize seedlings. | Acta biochimica Polonica 20040101 |
| Bidirectional regulation of renal cortical Na+,K+-ATPase by protein kinase C. | Acta biochimica Polonica 20040101 |
| [Cell shrinkage during apoptosis is not obligatory. Apoptosis of U937 cells induced by staurosporine and etoposide]. | Tsitologiia 20040101 |
| Regulation of gelatinases expression by cytokines, endotoxin, and pharmacological agents in the human osteoarthritic knee. | Connective tissue research 20040101 |
| Basal cell adhesion molecule is inversely associated with apoptosis, but plays a limited role for protection against apoptotic stimuli. | Skin pharmacology and physiology 20040101 |
| Signal transduction pathways involved in the platelet aggregation induced by a D-49 phospholipase A2 isolated from Bothrops jararacussu snake venom. | Biochimie 20040101 |
| Further studies on the hyperphosphorylated form (p40) of the rabies virus nominal phosphoprotein (P). | Microbiology and immunology 20040101 |
| Establishment of N-acetylmannosamine (ManNAc) analogue-resistant cell lines as improved hosts for sialic acid engineering applications. | Biotechnology progress 20040101 |
| Modification of physicochemical properties of actin filaments suppresses cell fragmentation in the execution phase of staurosporine-induced apoptotic processes. | Journal of electron microscopy 20040101 |
| Dexamethasone protected human glioblastoma U87MG cells from temozolomide induced apoptosis by maintaining Bax:Bcl-2 ratio and preventing proteolytic activities. | Molecular cancer 20040101 |
| Zebrafish apoptosis assays for drug discovery. | Methods in cell biology 20040101 |
| Retinol improves bovine embryonic development in vitro. | Reproductive biology and endocrinology : RB&E 20040101 |
| A possible involvement of plasma membrane NAD(P)H oxidase in the switch mechanism of the cell death mode from apoptosis to necrosis in menadione-induced cell injury. | Acta biochimica Polonica 20040101 |
| p19ARF-induced p53-independent apoptosis largely occurs through BAX. | Biochemical and biophysical research communications 20031226 |
| Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition. | Biochemical and biophysical research communications 20031226 |
| Insight into functional aspects of Stt3p, a subunit of the oligosaccharyl transferase. Evidence for interaction of the N-terminal domain of Stt3p with the protein kinase C cascade. | The Journal of biological chemistry 20031219 |
| Inhibition of staurosporine-induced neuronal cell death by bisphenol A and nonylphenol in primary cultured rat hippocampal and cortical neurons. | Neuroscience letters 20031219 |
| Antisense BAG-1 sensitizes HeLa cells to apoptosis by multiple pathways. | Biochemical and biophysical research communications 20031219 |
| Bovine DNase I: gene organization, mRNA expression, and changes in the topological distribution of the protein during apoptosis in lens epithelial cells. | Biochemical and biophysical research communications 20031219 |
| Hippocampal excitability increases during the estrous cycle in the rat: a potential role for brain-derived neurotrophic factor. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20031217 |
| Surface translocation of pactolus is induced by cell activation and death, but is not required for neutrophil migration and function. | Journal of immunology (Baltimore, Md. : 1950) 20031215 |
| Possible mechanisms underlying the mitogenic action of heptachlor in rat hepatocytes. | Toxicology and applied pharmacology 20031215 |
| Modulation of histamine-induced Ca2+ release by protein kinase C. Effects on cytosolic and mitochondrial [Ca2+] peaks. | The Journal of biological chemistry 20031212 |
| Hypoxia induces myocyte-dependent COX-2 regulation in endothelial cells: role of VEGF. | American journal of physiology. Heart and circulatory physiology 20031201 |
| Parathyroid hormone-related protein ameliorates death receptor-mediated apoptosis in lung cancer cells. | American journal of physiology. Cell physiology 20031201 |
| Phorbol esters and adenosine affect the readily releasable neurotransmitter pool by different mechanisms at amphibian motor nerve endings. | The Journal of physiology 20031201 |
| Transforming growth factor-beta induces expression of vascular endothelial growth factor in human retinal pigment epithelial cells: involvement of mitogen-activated protein kinases. | Journal of cellular physiology 20031201 |
| Spatial requirements for TrkA kinase activity in the support of neuronal survival and axon growth in rat sympathetic neurons. | Neuropharmacology 20031201 |
| In vitro anti-inflammatory and pro-aggregative effects of a lipid compound, petrocortyne A, from marine sponges. | Naunyn-Schmiedeberg's archives of pharmacology 20031201 |
| Expression of galectin-3 in neuronally differentiating PC12 cells is regulated both via Ras/MAPK-dependent and -independent signalling pathways. | Journal of neurochemistry 20031201 |
| On-line monitoring of apoptosis in insulin-secreting cells. | Diabetes 20031201 |
| Calphostin C as a rapid and strong inducer of apoptosis in human coronary artery smooth muscle cells. | International immunopharmacology 20031201 |
| Cellular mechanism for mibefradil-induced vasodilation of renal microcirculation: studies in the isolated perfused hydronephrotic kidney. | Journal of cardiovascular pharmacology 20031201 |
| Isoflurane enhances the expression and activity of glutamate transporter type 3 in C6 glioma cells. | Anesthesiology 20031201 |
| Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis. | Free radical biology & medicine 20031201 |
| Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) promotes mitochondrial dysfunction and apoptosis induced by 7-hydroxystaurosporine and mitogen-activated protein kinase kinase inhibitors in human leukemia cells that ectopically express Bcl-2 and Bcl-xL. | Molecular pharmacology 20031201 |
| Functional evaluation of the apoptosome in renal cell carcinoma. | British journal of cancer 20031201 |
| Protein synthesis is required for the transition to Ca(2+)-dependent regulated secretion in progesterone-matured Xenopus oocytes. | Journal of experimental zoology. Part A, Comparative experimental biology 20031201 |
| The expression of retinoblastoma and Sp1 is increased by low concentrations of cyclin-dependent kinase inhibitors. | European journal of biochemistry 20031201 |
| Effects of ohmefentanyl stereoisomers on phosphorylation of cAMP- response element binding protein in cultured rat hippocampal neurons. | Acta pharmacologica Sinica 20031201 |
| Different sensitivity to apoptosis in cells of monocytic or lymphocytic origin chronically infected with human immunodeficiency virus type-1. | Experimental biology and medicine (Maywood, N.J.) 20031201 |
| Dendritic cell viability is decreased after phagocytosis of apoptotic tumor cells induced by staurosporine or vaccinia virus infection. | Haematologica 20031201 |
| The bisphosphonate zoledronic acid induces cytotoxicity in human myeloma cell lines with enhancing effects of dexamethasone and thalidomide. | International journal of hematology 20031201 |
| Intracellular proteins involved in Porphyromonas gingivalis-induced opsonophagocytic activities of a murine macrophage cell line (RAW264.7 cells). | Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20031201 |
| IRAS is an anti-apoptotic protein. | Annals of the New York Academy of Sciences 20031201 |
| G-CSF modulates LPS-induced apoptosis and IL-8 in human microvascular endothelial cells: involvement of calcium signaling. | Annals of the New York Academy of Sciences 20031201 |
| Staurosporine induces apoptotic volume decrease (AVD) in ECV304 cells. | Annals of the New York Academy of Sciences 20031201 |
| The overexpression of Bcl-2 antagonizes the proapoptotic function of the kappa-opioid receptor. | Annals of the New York Academy of Sciences 20031201 |
| Drugs of abuse induce apoptotic features in PC12 cells. | Annals of the New York Academy of Sciences 20031201 |
| [Invasion of Aeromonas hydrophila in cells involving signal transduction and cytoskeleton]. | Wei sheng wu xue bao = Acta microbiologica Sinica 20031201 |
| Protein kinase C (PKC) isotype profile in eosinophils from ponies with sweet itch and role in histamine-induced eosinophil activation. | Veterinary immunology and immunopathology 20031115 |
| Overexpression of the immediate early gene fra-1 inhibits proliferation, induces apoptosis, and reduces tumourigenicity of c6 glioma cells. | Experimental cell research 20031115 |
| Small interfering RNA-mediated reduction in heterogeneous nuclear ribonucleoparticule A1/A2 proteins induces apoptosis in human cancer cells but not in normal mortal cell lines. | Cancer research 20031115 |
| Caspase activation increases beta-amyloid generation independently of caspase cleavage of the beta-amyloid precursor protein (APP). | The Journal of biological chemistry 20031114 |
| Nardosinone, the first enhancer of neurite outgrowth-promoting activity of staurosporine and dibutyryl cyclic AMP in PC12D cells. | Brain research. Developmental brain research 20031112 |
| Phosphorylation of Nrf2 at Ser40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expression. | The Journal of biological chemistry 20031107 |
| p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa. | Science (New York, N.Y.) 20031107 |
| Aryl[a]pyrrolo[3,4-c]carbazoles as selective cyclin D1-CDK4 inhibitors. | Bioorganic & medicinal chemistry letters 20031103 |
| Cigarette smoke prevents apoptosis through inhibition of caspase activation and induces necrosis. | American journal of respiratory cell and molecular biology 20031101 |
| The role of neurotrophin receptors in female germ-cell survival in mouse and human. | Development (Cambridge, England) 20031101 |
| PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis. | Nature neuroscience 20031101 |
| Progesterone induces the proliferation of urothelial cells in an epidermal growth factor dependent manner. | The Journal of urology 20031101 |
| Acquisition of anoikis resistance in human osteosarcoma cells. | European journal of cancer (Oxford, England : 1990) 20031101 |
| Induction by staurosporine of hepatocyte growth factor production in human skin fibroblasts independent of protein kinase inhibition. | Biochemical pharmacology 20031101 |
| A novel interaction between protein kinase D and TNF receptor-associated factor molecules regulates B cell receptor-CD40 synergy. | Journal of immunology (Baltimore, Md. : 1950) 20031101 |
| Cathepsin D mediates cytochrome c release and caspase activation in human fibroblast apoptosis induced by staurosporine. | Cell death and differentiation 20031101 |
| Interruption of the blood-stage cycle of the malaria parasite, Plasmodium chabaudi, by protein tyrosine kinase inhibitors. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20031101 |
| Periocular injection of microspheres containing PKC412 inhibits choroidal neovascularization in a porcine model. | Investigative ophthalmology & visual science 20031101 |
| Regulatory mechanisms and physiological relevance of a voltage-gated H+ channel in murine osteoclasts: phorbol myristate acetate induces cell acidosis and the channel activation. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20031101 |
| NGF activates the phosphorylation of MAP1B by GSK3beta through the TrkA receptor and not the p75(NTR) receptor. | Journal of neurochemistry 20031101 |
| Insulin induces cobalt uptake in a subpopulation of rat cultured primary sensory neurons. | The European journal of neuroscience 20031101 |
| The neurotoxicity induced by ethanol withdrawal in mature organotypic hippocampal slices might involve cross-talk between metabotropic glutamate type 5 receptors and N-methyl-D-aspartate receptors. | Alcoholism, clinical and experimental research 20031101 |
| Protection of mitochondrial perturbation by human T-lymphotropic virus type 1 tax through induction of Bcl-xL expression. | The Journal of laboratory and clinical medicine 20031101 |
| Cell cycle modulators for the treatment of lung malignancies. | Clinical lung cancer 20031101 |
| [Modulation of PKC inhibitor on growth cycle of human keratocyte]. | [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20031101 |
| Phorbol 12-myristate 13-acetate-induced ectodomain shedding and phosphorylation of the human meprinbeta metalloprotease. | The Journal of biological chemistry 20031031 |
| A rice isoflavone reductase-like gene, OsIRL, is induced by rice blast fungal elicitor. | Molecules and cells 20031031 |
| Interleukin-6 acts as an antiapoptotic factor in human esophageal carcinoma cells through the activation of both STAT3 and mitogen-activated protein kinase pathways. | Oncogene 20031030 |
| Bax is essential for mitochondrion-mediated apoptosis but not for cell death caused by photodynamic therapy. | British journal of cancer 20031020 |
| Structural characterization of the GSK-3beta active site using selective and non-selective ATP-mimetic inhibitors. | Journal of molecular biology 20031017 |
| Structural basis for UCN-01 (7-hydroxystaurosporine) specificity and PDK1 (3-phosphoinositide-dependent protein kinase-1) inhibition. | The Biochemical journal 20031015 |
| Regulation of endoplasmic reticulum Ca2+ dynamics by proapoptotic BCL-2 family members. | Biochemical pharmacology 20031015 |
| Connexins and apoptotic transformation. | Biochemical pharmacology 20031015 |
| Induction of C-anaphase and diplochromosome through dysregulation of spindle assembly checkpoint by sodium arsenite in human fibroblasts. | Cancer research 20031015 |
| KCl cotransport is an important modulator of human cervical cancer growth and invasion. | The Journal of biological chemistry 20031010 |
| Tissue inhibitor of metalloproteinase-1 protects human breast epithelial cells against intrinsic apoptotic cell death via the focal adhesion kinase/phosphatidylinositol 3-kinase and MAPK signaling pathway. | The Journal of biological chemistry 20031010 |
| The cyclin-dependent kinase 11(p46) isoform interacts with RanBPM. | Biochemical and biophysical research communications 20031010 |
| Mussel blood cells, resistant to the cytotoxic effects of okadaic acid, do not express cell membrane p-glycoprotein activity (multixenobiotic resistance). | Aquatic toxicology (Amsterdam, Netherlands) 20031008 |
| Sensory neurons from mice lacking the Brn-3b POU family transcription factor are resistant to death-inducing stimuli both in vitro and in vivo. | Brain research. Molecular brain research 20031007 |
| Cellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE). | The Journal of biological chemistry 20031003 |
| Thromboxane A2-induced inhibition of voltage-gated K+ channels and pulmonary vasoconstriction: role of protein kinase Czeta. | Circulation research 20031003 |
| Do anionic phospholipids serve as cofactors or second messengers for the regulation of activity of cloned ATP-sensitive K+ channels? | Circulation research 20031003 |
| Differential effects of staurosporine and its analogues on chemokine release by promyelocytic leukemia cell line NB-4. | Leukemia research 20031001 |
| Involvement of signaling through protein kinase C and phosphatidylinositol 3-kinase in the excystation and metacystic development of Entamoeba invadens. | Parasitology research 20031001 |
| PKC-zeta is required for angiotensin II-induced activation of ERK and synthesis of C-FOS in MCF-7 cells. | Journal of cellular physiology 20031001 |
| Human herpesvirus type 6 indirectly enhances oligodendrocyte cell death. | Journal of neurovirology 20031001 |
| Targeted expression of BCL-2 attenuates MPP+ but not 6-OHDA induced cell death in dopaminergic neurons. | Neurobiology of disease 20031001 |
| Caspase activity is not sufficient to execute cell death. | Experimental cell research 20031001 |
| Intracellular mechanism of mitochondrial adenosine triphosphate-sensitive potassium channel activation with isoflurane. | Anesthesia and analgesia 20031001 |
| Rapid, noninflammatory and PS-dependent phagocytic clearance of necrotic cells. | Cell death and differentiation 20031001 |
| Bifunctional apoptosis inhibitor (BAR) protects neurons from diverse cell death pathways. | Cell death and differentiation 20031001 |
| Cytometric analysis of protein expression and apoptosis in human primary cells with a novel microfluidic chip-based system. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20031001 |
| Cell death triggered by a novel mutation in the alphaA-crystallin gene underlies autosomal dominant cataract linked to chromosome 21q. | European journal of human genetics : EJHG 20031001 |
| Effect of agmatine against cell death induced by NMDA and glutamate in neurons and PC12 cells. | Cellular and molecular neurobiology 20031001 |
| Functional expression of the human thiazide-sensitive NaCl cotransporter in Madin-Darby canine kidney cells. | Journal of the American Society of Nephrology : JASN 20031001 |
| Sauchinone, a lignan from Saururus chinensis, inhibits staurosporine-induced apoptosis in C6 rat glioma cells. | Biological & pharmaceutical bulletin 20031001 |
| Ginsenoside Rg3 inhibits phenylephrine-induced vascular contraction through induction of nitric oxide synthase. | British journal of pharmacology 20031001 |
| Induction of colon cancer cell death by 7-hydroxystaurosporine (UCN-01) is associated with increased p38 MAPK and decreased Bcl-xL. | Anti-cancer drugs 20031001 |
| Expression of betaglycan, an inhibin coreceptor, in normal human ovaries and ovarian sex cord-stromal tumors and its regulation in cultured human granulosa-luteal cells. | The Journal of clinical endocrinology and metabolism 20031001 |
| Effects of ethanol on the rat glutamate excitatory amino acid transporter type 3 expressed in Xenopus oocytes: role of protein kinase C and phosphatidylinositol 3-kinase. | Alcoholism, clinical and experimental research 20031001 |
| [Development of the protein therapeutics using the super anti-cell death factor FNK]. | Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20031001 |
| Functional differences between growth plate apoptotic bodies and matrix vesicles. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20031001 |
| A comparison of the properties of a Bcl-xL variant to the wild-type anti-apoptosis inhibitor in mammalian cell cultures. | Metabolic engineering 20031001 |
| Human apurinic/apyrimidinic endonuclease (Ape1) and its N-terminal truncated form (AN34) are involved in DNA fragmentation during apoptosis. | The Journal of biological chemistry 20030926 |
| Beta-synuclein displays an antiapoptotic p53-dependent phenotype and protects neurons from 6-hydroxydopamine-induced caspase 3 activation: cross-talk with alpha-synuclein and implication for Parkinson's disease. | The Journal of biological chemistry 20030926 |
| Caspase-3-mediated cleavage of Rad9 during apoptosis. | Oncogene 20030925 |
| Enhanced oligodendrocyte survival after spinal cord injury in Bax-deficient mice and mice with delayed Wallerian degeneration. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030924 |
| Acidic polysaccharide isolated from Phellinus linteus induces nitric oxide-mediated tumoricidal activity of macrophages through protein tyrosine kinase and protein kinase C. | Biochemical and biophysical research communications 20030919 |
| Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA). | The Biochemical journal 20030915 |
| Glycogen synthase kinase-3 regulates formation of long lamellipodia in human keratinocytes. | Journal of cell science 20030915 |
| Transcriptional and translational control of Mcl-1 during apoptosis. | Archives of biochemistry and biophysics 20030915 |
| Macrocyclic bisindolylmaleimides as inhibitors of protein kinase C and glycogen synthase kinase-3. | Bioorganic & medicinal chemistry letters 20030915 |
| Glia-conditioned medium induces de novo synthesis of tyrosine hydroxylase and increases dopamine cell survival by differential signaling pathways. | Journal of neuroscience research 20030915 |
| High pressure induces superoxide production in isolated arteries via protein kinase C-dependent activation of NAD(P)H oxidase. | Circulation 20030909 |
| Wilms' tumor suppressor (WT1) is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer's disease. | Brain research 20030905 |
| Heat shock protein 70 binds caspase-activated DNase and enhances its activity in TCR-stimulated T cells. | Blood 20030901 |
| Synergistic antileukemic interactions between 17-AAG and UCN-01 involve interruption of RAF/MEK- and AKT-related pathways. | Blood 20030901 |
| Motorcycle exhaust particulates enhance vasoconstriction in organ culture of rat aortas and involve reactive oxygen species. | Toxicological sciences : an official journal of the Society of Toxicology 20030901 |
| Signalling pathways involved in the sensitisation of mouse nociceptive neurones by nerve growth factor. | The Journal of physiology 20030901 |
| Extracellular signal-regulated kinases and contractile responses in ovine adult and fetal cerebral arteries. | The Journal of physiology 20030901 |
| Detailed in vitro pharmacological analysis of FK506-induced neuroprotection. | Neuropharmacology 20030901 |
| Detection and characterization of a rat parotid gland protein kinase that catalyzes phosphorylation of matured destrin at Ser-2. | Archives of oral biology 20030901 |
| Proteoglycan isolated from Phellinus linteus activates murine B lymphocytes via protein kinase C and protein tyrosine kinase. | International immunopharmacology 20030901 |
| Pyruvate inhibits zinc-mediated pancreatic islet cell death and diabetes. | Diabetologia 20030901 |
| Potassium channel gene therapy can prevent neuron death resulting from necrotic and apoptotic insults. | Journal of neurochemistry 20030901 |
| Mycobacterium tuberculosis infection causes different levels of apoptosis and necrosis in human macrophages and alveolar epithelial cells. | Cellular microbiology 20030901 |
| Lack of Apaf-1 expression confers resistance to cytochrome c-driven apoptosis in cardiomyocytes. | Cell death and differentiation 20030901 |
| Stress-induced apoptosis is impaired in cells with a lysosomal targeting defect but is not affected in cells synthesizing a catalytically inactive cathepsin D. | Cell death and differentiation 20030901 |
| Association between mitotic spindle checkpoint impairment and susceptibility to the induction of apoptosis by anti-microtubule agents in human lung cancers. | The American journal of pathology 20030901 |
| Staurosporine-induced apoptosis in human cornea epithelial cells in vitro. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20030901 |
| Glucose-induced TGF-beta1 and TGF-beta receptor-1 expression in vascular smooth muscle cells is mediated by protein kinase C-alpha. | Hypertension (Dallas, Tex. : 1979) 20030901 |
| Effect of ATP on Ca2+ uptake in the presence of high glucose in renal proximal tubule cells. | Clinical and experimental pharmacology & physiology 20030901 |
| Mitochondrial release of AIF and EndoG requires caspase activation downstream of Bax/Bak-mediated permeabilization. | The EMBO journal 20030901 |
| A tetrameric glycoprotein Ib-binding protein, agglucetin, from Formosan pit viper: structure and interaction with human platelets. | Thrombosis and haemostasis 20030901 |
| Staurosporine induces rapid homotypic intercellular adhesion of U937 cells via multiple kinase activation. | British journal of pharmacology 20030901 |
| Identification of novel gene expression targets for the Ras association domain family 1 (RASSF1A) tumor suppressor gene in non-small cell lung cancer and neuroblastoma. | Cancer research 20030901 |
| [Effect of angiotensin II on tissue factor expression in human peripheral blood monocytes and its mechanisms]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20030901 |
| Isolation of bisindole alkaloids that inhibit the cell cycle from Myxomycetes Arcyria ferruginea and Tubifera casparyi. | Bioorganic & medicinal chemistry letters 20030901 |
| Sucrose increases calcium-dependent protein kinase and phosphatase activities in potato plants. | Cellular and molecular biology (Noisy-le-Grand, France) 20030901 |
| Flagellar adhesion between mating type plus and mating type minus gametes activates a flagellar protein-tyrosine kinase during fertilization in Chlamydomonas. | The Journal of biological chemistry 20030829 |
| Inhibition of apoptosis by recombinant 30K protein originating from silkworm hemolymph. | Biochemical and biophysical research communications 20030829 |
| Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis. | The Journal of biological chemistry 20030815 |
| An overactivated ATR/CHK1 pathway is responsible for the prolonged G2 accumulation in irradiated AT cells. | The Journal of biological chemistry 20030815 |
| Insulin induces the expression of the SHARP-2/Stra13/DEC1 gene via a phosphoinositide 3-kinase pathway. | The Journal of biological chemistry 20030815 |
| GABAB receptor transduction mechanisms, and cross-talk between protein kinases A and C, in GABAergic terminals synapsing onto neurons of the rat nucleus basalis of Meynert. | The Journal of physiology 20030815 |
| Pathogen-associated molecular patterns sensitize macrophages to Fas ligand-induced apoptosis and IL-1 beta release. | Journal of immunology (Baltimore, Md. : 1950) 20030815 |
| Postmitochondrial regulation of apoptosis by bicarbonate. | Experimental cell research 20030815 |
| Apoptosome-independent pathway for apoptosis. Biochemical analysis of APAF-1 defects and biological outcomes. | The Journal of biological chemistry 20030808 |
| Possible involvement of Wiskott-Aldrich syndrome protein family in aberrant neuronal sprouting in Alzheimer's disease. | Neuroscience letters 20030807 |
| Sustained intracellular Ca2+ elevation induced by a brief BDNF application in rat visual cortex neurons. | Neuroreport 20030806 |
| Adhesion-associated and PKC-modulated changes in serine/threonine phosphorylation of p120-catenin. | Biochemistry 20030805 |
| Involvement of Rho-kinase in contraction of guinea-pig aorta induced by prostanoid EP3 receptor agonists. | British journal of pharmacology 20030802 |
| Histamine inhibits atrial myocytic ANP release via H2 receptor-cAMP-protein kinase signaling. | American journal of physiology. Regulatory, integrative and comparative physiology 20030801 |
| Expression of alternatively spliced interleukin-1 receptor accessory protein mRNAs is differentially regulated during inflammation and apoptosis. | Cellular signalling 20030801 |
| Staurosporine-inhibitable protein kinase activity associated with secretory granule membranes isolated from rat submandibular gland cells. | Archives of oral biology 20030801 |
| Pepstatin A induces extracellular acidification distinct from aspartic protease inhibition in microglial cell lines. | Glia 20030801 |
| Intracellular signaling pathways involved in mediating the effects of lead on the transcription factor Sp1. | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20030801 |
| Rottlerin, an inhibitor of protein kinase Cdelta (PKCdelta), inhibits astrocytic glutamate transport activity and reduces GLAST immunoreactivity by a mechanism that appears to be PKCdelta-independent. | Journal of neurochemistry 20030801 |
| Infection of human urethral epithelium with Neisseria gonorrhoeae elicits an upregulation of host anti-apoptotic factors and protects cells from staurosporine-induced apoptosis. | Cellular microbiology 20030801 |
| IRAS, the human homologue of Nischarin, prolongs survival of transfected PC12 cells. | Cell death and differentiation 20030801 |
| The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor. | Genes & development 20030801 |
| Lidocaine attenuates cytokine-induced cell injury in endothelial and vascular smooth muscle cells. | Anesthesia and analgesia 20030801 |
| Protein kinase C activation downregulates human organic anion transporter 1-mediated transport through carrier internalization. | Journal of the American Society of Nephrology : JASN 20030801 |
| Apoptosis-resistance of hypoxic cells: multiple factors involved and a role for IAP-2. | The American journal of pathology 20030801 |
| The kinase inhibitor PKC412 suppresses epiretinal membrane formation and retinal detachment in mice with proliferative retinopathies. | Investigative ophthalmology & visual science 20030801 |
| Phorbol ester induces CYP2E1 in astrocytes, through a protein kinase C- and tyrosine kinase-dependent mechanism. | Journal of neurochemistry 20030801 |
| Involvement of mitochondrial K+ release and cellular efflux in ischemic and apoptotic neuronal death. | Journal of neurochemistry 20030801 |
| Diverse regulation of atrial natriuretic peptide secretion by serotonin receptor subtypes. | Cardiovascular research 20030801 |
| Staurosporine is a potent activator of neuronal, glial, and 'CNS stem cell-like' neurosphere differentiation in murine embryonic stem cells. | Molecular and cellular neurosciences 20030801 |
| Simultaneous inhibition of focal adhesion kinase and SRC enhances detachment and apoptosis in colon cancer cell lines. | Molecular cancer research : MCR 20030801 |
| Expression of dengue ApoptoM sequence results in disruption of mitochondrial potential and caspase activation. | Biochimie 20030801 |
| Acute pancreatitis results in referred mechanical hypersensitivity and neuropeptide up-regulation that can be suppressed by the protein kinase inhibitor k252a. | The journal of pain : official journal of the American Pain Society 20030801 |
| Nucleolus in apoptosis-induced mouse preimplantation embryos. | Zygote (Cambridge, England) 20030801 |
| Teratogen-induced activation of caspase-6 and caspase-7 in early postimplantation mouse embryos. | Cell biology and toxicology 20030801 |
| Modulation of the Na(+)-H(+) antiport activity by adrenaline on erythrocytes from normal and obese individuals. | Molecular and cellular endocrinology 20030731 |
| Oligomerization-induced modulation of TPR-MET tyrosine kinase activity. | The Journal of biological chemistry 20030725 |
| Agonist-independent desensitization and internalization of the human platelet-activating factor receptor by coumermycin-gyrase B-induced dimerization. | The Journal of biological chemistry 20030725 |
| VDAC2 inhibits BAK activation and mitochondrial apoptosis. | Science (New York, N.Y.) 20030725 |
| Dopamine D1 receptor-dependent inhibition of NaCl transport in the rat thick ascending limb: mechanism of action. | European journal of pharmacology 20030725 |
| Lysophosphatidic acid induces alpha1B-adrenergic receptor phosphorylation through G beta gamma, phosphoinositide 3-kinase, protein kinase C and epidermal growth factor receptor transactivation. | Biochimica et biophysica acta 20030721 |
| Temperature-modulated diversity of TRPV4 channel gating: activation by physical stresses and phorbol ester derivatives through protein kinase C-dependent and -independent pathways. | The Journal of biological chemistry 20030718 |
| Proteolytic regulation of Forkhead transcription factor FOXO3a by caspase-3-like proteases. | Oncogene 20030717 |
| Sensitivity toward tyrosine kinase inhibitors varies between different activating mutations of the FLT3 receptor. | Blood 20030715 |
| Rapid detection of apoptosis through real-time reverse transcriptase polymerase chain reaction measurement of the small cytoplasmic RNA Y1. | Analytical biochemistry 20030715 |
| Role of protein kinase C in BSA-AGE-mediated inducible nitric oxide synthase expression in RAW 264.7 macrophages. | Biochemical pharmacology 20030715 |
| Distribution of myocilin, a glaucoma gene product, in human corneal fibroblasts. | Molecular vision 20030703 |
| The trophic role of oligodendrocytes in the basal forebrain. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030702 |
| Inhibition of staurosporine-induced apoptosis of endothelial cells by activated protein C requires protease-activated receptor-1 and endothelial cell protein C receptor. | The Biochemical journal 20030701 |
| Inhibition of protein kinase CbetaII increases glucose uptake in 3T3-L1 adipocytes through elevated expression of glucose transporter 1 at the plasma membrane. | Molecular endocrinology (Baltimore, Md.) 20030701 |
| Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK. | Nature cell biology 20030701 |
| Nuclear translocation and retention of growth hormone. | Endocrinology 20030701 |
| Stimulation of catecholamine synthesis by orexin-A in bovine adrenal medullary cells through orexin receptor 1. | Biochemical pharmacology 20030701 |
| Mutation (D472Y) in the type 3 repeat domain of cartilage oligomeric matrix protein affects its early vesicle trafficking in endoplasmic reticulum and induces apoptosis. | The American journal of pathology 20030701 |
| Survival-signaling pathway as a promising target for cancer chemotherapy. | Cancer chemotherapy and pharmacology 20030701 |
| Novel direct and indirect cyclin-dependent kinase modulators for the prevention and treatment of human neoplasms. | Cancer chemotherapy and pharmacology 20030701 |
| Staurosporine induces apoptosis in NG108-15 cells. | Acta pharmacologica Sinica 20030701 |
| Interleukin-10 activation of the interleukin-10E1 pathway and tissue inhibitor of metalloproteinase-1 expression is enhanced by proteasome inhibitors in primary prostate tumor lines. | Molecular cancer research : MCR 20030701 |
| [Effect of staurosporine on cell cycle of human gastric cancer cells]. | Ai zheng = Aizheng = Chinese journal of cancer 20030701 |
| Inhibition of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase enhances chemotherapeutic effects on H460 human non-small cell lung cancer cells through activation of apoptosis. | Molecular cancer therapeutics 20030701 |
| Norepinephrine-induced inositol 1,4,5-trisphosphate formation in atrial myocytes is regulated by extracellular calcium, protein kinase C, and calmodulin. | Japanese heart journal 20030701 |
| Increase in anthraquinone content in Rubia cordifolia cells transformed by rol genes does not involve activation of the NADPH oxidase signaling pathway. | Biochemistry. Biokhimiia 20030701 |
| Effects of Ca(2+) channel blockers and protein kinase/phosphatase inhibitors on growth and anthraquinone production in Rubia cordifolia callus cultures transformed by the rolB and rolC genes. | Planta 20030701 |
| Triggering of apoptosis is not sufficient to induce human immunodeficiency virus gene expression. | IUBMB life 20030701 |
| Protein phosphorylation during the process of interaction of Toxoplasma gondii with host cells. | Journal of submicroscopic cytology and pathology 20030701 |
| Phosphatidic acid induces actin polymerization by activating protein kinases in soybean cells. | Molecules and cells 20030630 |
| Loss of HSulf-1 up-regulates heparin-binding growth factor signaling in cancer. | The Journal of biological chemistry 20030620 |
| Galectin-3 expression in macrophages is signaled by Ras/MAP kinase pathway and up-regulated by modified lipoproteins. | Biochimica et biophysica acta 20030617 |
| A homogeneous, nonradioactive high-throughput fluorogenic protein kinase assay. | Analytical biochemistry 20030615 |
| Mediation of neuronal apoptosis by Kv2.1-encoded potassium channels. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030615 |
| Role of Ca2+ feedback on single cell inositol 1,4,5-trisphosphate oscillations mediated by G-protein-coupled receptors. | The Journal of biological chemistry 20030606 |
| Identification of chelerythrine as an inhibitor of BclXL function. | The Journal of biological chemistry 20030606 |
| Measuring the mitotic index in chemically-treated human lymphocyte cultures by flow cytometry. | Mutation research 20030606 |
| Effects of propofol on the activity of rat glutamate transporter type 3 expressed in Xenopus oocytes: the role of protein kinase C. | Neuroscience letters 20030605 |
| Acyclic N-(azacycloalkyl)bisindolylmaleimides: isozyme selective inhibitors of PKCbeta. | Bioorganic & medicinal chemistry letters 20030602 |
| Recombinant mistletoe lectin induces p53-independent apoptosis in tumour cells and cooperates with ionising radiation. | British journal of cancer 20030602 |
| Role of cyclooxygenase-1 and -2, phospholipase C, and protein kinase C in prostaglandin-mediated gastroprotection. | The Journal of pharmacology and experimental therapeutics 20030601 |
| Altered 5-HT-induced calcium response in the presence of staurosporine in blood platelets from bipolar disorder patients. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030601 |
| Decreases in ANP secretion by lysophosphatidylcholine through protein kinase C. | Hypertension (Dallas, Tex. : 1979) 20030601 |
| Apoptosis repressor with caspase domain inhibits cardiomyocyte apoptosis by reducing K+ currents. | American journal of physiology. Cell physiology 20030601 |
| Angiotensin II-induced ionic currents and signalling pathways in submandibular ganglion neurons. | Archives of oral biology 20030601 |
| Variations in cell signaling pathways for different vasoconstrictor agonists in renal circulation of the rat. | Kidney international 20030601 |
| A novel homocysteine-responsive gene, smap8, modulates mitogenesis in rat vascular smooth muscle cells. | European journal of biochemistry 20030601 |
| Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease. | Human molecular genetics 20030601 |
| Immunofluorescent detection of activation of initiator caspases-8 and -9 during pharmacologically induced apoptosis of cultured HeLa and endothelial cells. | Histochemistry and cell biology 20030601 |
| Neurites undergoing Wallerian degeneration show an apoptotic-like process with Annexin V positive staining and loss of mitochondrial membrane potential. | Neuroscience research 20030601 |
| Methioninase gene therapy with selenomethionine induces apoptosis in bcl-2-overproducing lung cancer cells. | Cancer gene therapy 20030601 |
| Vascular endothelial growth factor increases heme oxygenase-1 protein expression in the chick embryo chorioallantoic membrane. | British journal of pharmacology 20030601 |
| Matrix metalloproteinase 2 and matrix metalloproteinase 9 expression in human oral squamous cell carcinoma and the effect of protein kinase C inhibitors: preliminary observations. | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20030601 |
| Activating MAP KAP kinase 2. | Structure (London, England : 1993) 20030601 |
| Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme. | Structure (London, England : 1993) 20030601 |
| Hsp70 prevents nitric oxide-induced apoptosis in articular chondrocytes. | Arthritis and rheumatism 20030601 |
| Possible involvement of energy metabolism in the change of cytoplasm organization induced by a protein phosphatase inhibitor, calyculin A, in root hair cells of Limnobium stoloniferum. | Protoplasma 20030601 |
| Adenoviral melanoma differentiation-associated gene 7 induces apoptosis in lung cancer cells through mitochondrial permeability transition-independent cytochrome c release. | The Journal of thoracic and cardiovascular surgery 20030601 |
| The role of estrogen-dependent progesterone receptor in protein kinase C-mediated LH secretion and GnRH self-priming in rat anterior pituitary glands. | Journal of endocrinological investigation 20030601 |
| Pharmacological studies supporting the therapeutic use of Ginkgo biloba extract for Alzheimer's disease. | Pharmacopsychiatry 20030601 |
| Effects of simulated microgravity on nitric oxide level in cardiac myocytes and its mechanism. | Science in China. Series C, Life sciences 20030601 |
| Regulatory mechanism of Cordyceps sinensis mycelium on mouse Leydig cell steroidogenesis. | FEBS letters 20030522 |
| Apoptotic insults impair Na+, K+-ATPase activity as a mechanism of neuronal death mediated by concurrent ATP deficiency and oxidant stress. | Journal of cell science 20030515 |
| Multiprotein bridging factor 1 cooperates with c-Jun and is necessary for cardiac hypertrophy in vitro. | Experimental cell research 20030515 |
| Evidence for protein tyrosine phosphatase, tyrosine kinase, and G-protein regulation of the parallel fiber metabotropic slow EPSC of rat cerebellar Purkinje neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030515 |
| Effects of ginsenoside on G protein-coupled inwardly rectifying K+ channel activity expressed in Xenopus oocytes. | European journal of pharmacology 20030509 |
| Interleukin-8-mediated heterologous receptor internalization provides resistance to HIV-1 infectivity. Role of signal strength and receptor desensitization. | The Journal of biological chemistry 20030502 |
| Rabies virus nucleoprotein is phosphorylated by cellular casein kinase II. | Biochemical and biophysical research communications 20030502 |
| Cytochrome c translocation does not lead to caspase activation in maitotoxin-treated SH-SY5Y neuroblastoma cells. | Neurochemistry international 20030501 |
| Induction of cyclooxygenase-2 by lipopolysaccharide in canine tracheal smooth muscle cells: involvement of p42/p44 and p38 mitogen-activated protein kinases and nuclear factor-kappaB pathways. | Cellular signalling 20030501 |
| Activation of P2Y2 receptor induces c-FOS protein through a pathway involving mitogen-activated protein kinases and phosphoinositide 3-kinases in HeLa cells. | Journal of cellular physiology 20030501 |
| Secretoneurin promotes pertussis toxin-sensitive neurite outgrowth in cerebellar granule cells. | Journal of neurochemistry 20030501 |
| A fluorescence polarization assay for native protein substrates of kinases. | Analytical biochemistry 20030501 |
| Early necrotic DNA degradation: presence of blunt-ended DNA breaks, 3' and 5' overhangs in apoptosis, but only 5' overhangs in early necrosis. | The American journal of pathology 20030501 |
| Tyrosine phosphorylation of I-kappa B kinase alpha/beta by protein kinase C-dependent c-Src activation is involved in TNF-alpha-induced cyclooxygenase-2 expression. | Journal of immunology (Baltimore, Md. : 1950) 20030501 |
| Regulation of cell survival in the developing thalamus: an in vitro analysis. | Experimental neurology 20030501 |
| Combination therapy with irinotecan and protein kinase C inhibitors in malignant glioma. | Cancer 20030501 |
| An MMP-2/MMP-9 inhibitor, 5a, enhances apoptosis induced by ligands of the TNF receptor superfamily in cancer cells. | Cell death and differentiation 20030501 |
| Regulation of K-Cl cotransport by Syk and Src protein tyrosine kinases in deoxygenated sickle cells. | Pflugers Archiv : European journal of physiology 20030501 |
| Modulation of gap junction mediated intercellular communication in TM3 Leydig cells. | The Journal of endocrinology 20030501 |
| Stathmin expression and megakaryocyte differentiation: a potential role in polyploidy. | Experimental hematology 20030501 |
| PKC412 overcomes resistance to imatinib in a murine model of FIP1L1-PDGFRα-induced myeloproliferative disease. | Cancer cell 20030501 |
| Sex steroid hormones do not influence the oxidative burst activity of polymorphonuclear leukocytes from ovariectomized cows in vitro. | Steroids 20030501 |
| Pentoxifylline induced signalling events during capacitation of hamster spermatozoa: significance of protein tyrosine phosphorylation. | Cellular and molecular biology (Noisy-le-Grand, France) 20030501 |
| Down-regulation of cell surface CXCR6 expression during T cell activation is predominantly mediated by calcineurin. | Cellular immunology 20030501 |
| Bfl-1S, a novel alternative splice variant of Bfl-1, localizes in the nucleus via its C-terminus and prevents cell death. | Oncogene 20030424 |
| Cross-talk between calpain and caspase proteolytic systems during neuronal apoptosis. | The Journal of biological chemistry 20030418 |
| Pharmacological characteristics of bombesin receptor mediating hypothermia in the central nervous system of rats. | Brain research 20030418 |
| Endothelin-1 stimulates glial cell line-derived neurotrophic factor expression in cultured rat astrocytes. | Biochemical and biophysical research communications 20030418 |
| The vascular response to the K+ channel inhibitor 4-aminopyridine in hypertensive rats. | European journal of pharmacology 20030418 |
| Modulation of cell death by alpha-synuclein is stimulus-dependent in mammalian cells. | Neuroscience letters 20030417 |
| Mechanics of cell spreading: role of myosin II. | Journal of cell science 20030415 |
| Survivin acts as an antiapoptotic factor during the development of mouse preimplantation embryos. | Developmental biology 20030415 |
| Receptor activator of nuclear factor kappaB ligand plays a nonredundant role in doxorubicin-induced apoptosis. | Cancer research 20030415 |
| Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030415 |
| Mitochondrial membrane permeabilization and superoxide production during apoptosis. A single-cell analysis. | The Journal of biological chemistry 20030411 |
| Huperzine A attenuates the neurotoxic effect of staurosporine in primary rat cortical neurons. | Neuroscience letters 20030410 |
| The C-terminal fragment of presenilin 2 triggers p53-mediated staurosporine-induced apoptosis, a function independent of the presenilinase-derived N-terminal counterpart. | The Journal of biological chemistry 20030404 |
| Transforming growth factor-beta1 potentiates renal tubular epithelial cell death by a mechanism independent of Smad signaling. | The Journal of biological chemistry 20030404 |
| Signalling pathways involved in the short-term potentiation of dopamine release by BDNF. | Brain research 20030404 |
| Disulfonic stilbenes prevent beta-amyloid (25-35) neuronal toxicity in rat cortical cultures. | Neuroscience letters 20030403 |
| Renal tubular epithelial cell apoptosis is associated with caspase cleavage of the NHE1 Na+/H+ exchanger. | American journal of physiology. Renal physiology 20030401 |
| TERT suppresses apoptotis at a premitochondrial step by a mechanism requiring reverse transcriptase activity and 14-3-3 protein-binding ability. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030401 |
| Protein kinase C and phosphoinositol-3-kinase mediate differentiation or proliferation of slice-derived rat microglia. | Pharmacology 20030401 |
| Alpha 1-adrenoceptor-activated cation currents in neurones acutely isolated from rat cardiac parasympathetic ganglia. | The Journal of physiology 20030401 |
| Calyculin A-induced actin phosphorylation and depolymerization in renal epithelial cells. | Cell motility and the cytoskeleton 20030401 |
| The adenosine inhibition of glutamate exocytosis in synaptosomes is removed by the collapse of the vesicle-cytosol deltapH plus the opening of farnesol-sensitive Ca(2+) channels. | Cell calcium 20030401 |
| Length-dependent regulation of basal myosin phosphorylation and force in detrusor smooth muscle. | American journal of physiology. Regulatory, integrative and comparative physiology 20030401 |
| Ceramide in rafts (detergent-insoluble fraction) mediates cell death in neurotumor cell lines. | Journal of neuroscience research 20030401 |
| Cytoprotective membrane-permeable peptides designed from the Bax-binding domain of Ku70. | Nature cell biology 20030401 |
| Altered expression and uptake activity of spinal glutamate transporters after nerve injury contribute to the pathogenesis of neuropathic pain in rats. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030401 |
| Staurosporine-induced apoptosis is independent of p16 and p21 and achieved via arrest at G2/M and at G1 in U251MG human glioma cell line. | Cancer chemotherapy and pharmacology 20030401 |
| Cell cycle-dependent potentiation of cisplatin by UCN-01 in non-small-cell lung carcinoma. | Cancer chemotherapy and pharmacology 20030401 |
| Effect of protein kinase C activation and inhibition on rat hepatic stellate cell activation. | Digestive diseases and sciences 20030401 |
| Mineralocorticoid receptor expression and increased survival following neuronal injury. | The European journal of neuroscience 20030401 |
| Effect of lipopolysaccharide on D-fructose transport across rabbit jejunum. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030401 |
| Phorbol ester stimulates expression of the human tryptophanyl-tRNA synthetase gene. | Biochemistry. Biokhimiia 20030401 |
| A fluorescence microplate assay using yopro-1 to measure apoptosis: application to HL60 cells subjected to oxidative stress. | Cell biology and toxicology 20030401 |
| A homogeneous fluorescence polarization assay adaptable for a range of protein serine/threonine and tyrosine kinases. | Journal of biomolecular screening 20030401 |
| Effects of docosapentaenoic acid on neuronal apoptosis. | Lipids 20030401 |
| Tubulyzine, a novel tri-substituted triazine, prevents the early cell death of transplanted myogenic cells and improves transplantation success. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20030401 |
| Epoxycyclohexenone inhibits Fas-mediated apoptosis by blocking activation of pro-caspase-8 in the death-inducing signaling complex. | The Journal of biological chemistry 20030328 |
| Neuroprotective effects of alpha-tocopherol on oxidative stress in rat striatal cultures. | European journal of pharmacology 20030328 |
| C-terminal 15 kDa fragment of cytoskeletal actin is posttranslationally N-myristoylated upon caspase-mediated cleavage and targeted to mitochondria. | FEBS letters 20030327 |
| Tumoricidal activity of lauryl gallate towards chemically induced skin tumours in mice. | British journal of cancer 20030324 |
| Cellular prion protein sensitizes neurons to apoptotic stimuli through Mdm2-regulated and p53-dependent caspase 3-like activation. | The Journal of biological chemistry 20030321 |
| Late Simian virus 40 transcription factor is a target of the phosphoinositide 3-kinase/Akt pathway in anti-apoptotic Alzheimer's amyloid precursor protein signalling. | The Biochemical journal 20030315 |
| Prothrombin binds to the surface of apoptotic, but not viable, cells and serves as a target of lupus anticoagulant autoantibodies. | Journal of immunology (Baltimore, Md. : 1950) 20030315 |
| Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor. | Science (New York, N.Y.) 20030314 |
| c-Src-dependent tyrosine phosphorylation of IKKbeta is involved in tumor necrosis factor-alpha-induced intercellular adhesion molecule-1 expression. | The Journal of biological chemistry 20030314 |
| Do cancer cells die because of Nogo-B? | Oncogene 20030306 |
| Vitamin E (alpha-tocopherol) attenuates cyclo-oxygenase 2 transcription and synthesis in immortalized murine BV-2 microglia. | The Biochemical journal 20030301 |
| Human osteoblast-like cell proliferation induced by calcitonin-related peptides involves PKC activity. | American journal of physiology. Endocrinology and metabolism 20030301 |
| Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death. | Human molecular genetics 20030301 |
| Mechanisms of staurosporine induced apoptosis in a human corneal endothelial cell line. | The British journal of ophthalmology 20030301 |
| The survival effect of prolactin on PC3 prostate cancer cells. | European urology 20030301 |
| Interaction of caspase-3 with the cyclic GMP binding cyclic GMP specific phosphodiesterase (PDE5a1). | European journal of biochemistry 20030301 |
| Acidosis has opposite effects on neuronal survival during hypoxia and reoxygenation. | Journal of neurochemistry 20030301 |
| An age-related increase in resistance to DNA damage-induced apoptotic cell death is associated with development of DNA repair mechanisms. | Journal of neurochemistry 20030301 |
| Apoptotic susceptibility of cancer cells selected for camptothecin resistance: gene expression profiling, functional analysis, and molecular interaction mapping. | Cancer research 20030301 |
| Protein kinase antagonists inhibit invasion of mammalian cells by Fonsecaea pedrosoi. | Journal of medical microbiology 20030301 |
| Novel diketopiperazine enhances motor and cognitive recovery after traumatic brain injury in rats and shows neuroprotection in vitro and in vivo. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20030301 |
| Shedding of growth-suppressive gangliosides from glomerular mesangial cells undergoing apoptosis. | Kidney international 20030301 |
| Targeting aurora2 kinase in oncogenesis: a structural bioinformatics approach to target validation and rational drug design. | Molecular cancer therapeutics 20030301 |
| Chlorophyll antenna size adjustments by irradiance in Dunaliella salina involve coordinate regulation of chlorophyll a oxygenase (CAO) and Lhcb gene expression. | Plant molecular biology 20030301 |
| Regulation of sympathetic neuron and neuroblastoma cell death by XIAP and its association with proteasomes in neural cells. | Molecular and cellular neurosciences 20030301 |
| Agrin regulates rapsyn interaction with surface acetylcholine receptors, and this underlies cytoskeletal anchoring and clustering. | The Journal of biological chemistry 20030227 |
| Gelsolin suppresses tumorigenicity through inhibiting PKC activation in a human lung cancer cell line, PC10. | British journal of cancer 20030224 |
| Bcl-2 on the endoplasmic reticulum regulates Bax activity by binding to BH3-only proteins. | The Journal of biological chemistry 20030221 |
| Tensile stress-dependent collagen XII and fibronectin production by fibroblasts requires separate pathways. | Biochimica et biophysica acta 20030217 |
| Staurosporine-induced death of MCF-7 human breast cancer cells: a distinction between caspase-3-dependent steps of apoptosis and the critical lethal lesions. | Experimental cell research 20030215 |
| Albumin stimulates interleukin-8 expression in proximal tubular epithelial cells in vitro and in vivo. | The Journal of clinical investigation 20030215 |
| Effect of PKC412, a selective inhibitor of protein kinase C, on lung metastasis in mice injected with B16 melanoma cells. | Life sciences 20030207 |
| Involvement of protein kinase C in glutamate release from cultured microglia. | Brain research 20030207 |
| Insulin or bFGF and C2 ceramide increase newborn rat retinal ganglion cell survival rate. | Biochemical and biophysical research communications 20030207 |
| Human replication protein Cdc6 prevents mitosis through a checkpoint mechanism that implicates Chk1. | The EMBO journal 20030203 |
| Caspase activation pathways induced by staurosporine and low potassium: role of caspase-2. | Journal of neuroscience research 20030201 |
| Selective suppression of cathepsin L by antisense cDNA impairs human brain tumor cell invasion in vitro and promotes apoptosis. | Cancer gene therapy 20030201 |
| Inhibition of nucleoside transport by protein kinase inhibitors. | The Journal of pharmacology and experimental therapeutics 20030201 |
| Differentiation and apoptosis in human immortalized sebocytes. | The Journal of investigative dermatology 20030201 |
| Arachidonic acid and anandamide have opposite modulatory actions at the glycine transporter, GLYT1a. | Journal of neurochemistry 20030201 |
| A parallel signal-transduction pathway for eotaxin- and interleukin-5-induced eosinophil shape change. | Immunology 20030201 |
| Essential role for integrin linked kinase in Akt-mediated integrin survival signaling in hippocampal neurons. | Journal of neurochemistry 20030201 |
| Decreased caspase-3 activity in human lens epithelium from posterior subcapsular cataracts. | Experimental eye research 20030201 |
| Role of protein kinases on acid-induced duodenal bicarbonate secretion in rats. | Pharmacology 20030201 |
| The effect of chelerythrine on depolarization-induced force responses in skinned fast skeletal muscle fibres of the rat. | British journal of pharmacology 20030201 |
| Involvement of actin polymerization in vesicle recruitment at the calyx of Held synapse. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030201 |
| Apoptotic PC12 cells exposing phosphatidylserine promote the production of anti-inflammatory and neuroprotective molecules by microglial cells. | Journal of neuropathology and experimental neurology 20030201 |
| Neisserial PorB is translocated to the mitochondria of HeLa cells infected with Neisseria meningitidis and protects cells from apoptosis. | Cellular microbiology 20030201 |
| Searching for mechanisms of N-methyl-D-aspartate-induced glutathione efflux in organotypic hippocampal cultures. | Neurochemical research 20030201 |
| Inhibition of FLT3 in MLL. Validation of a therapeutic target identified by gene expression based classification. | Cancer cell 20030201 |
| Modulation of the contractile and biosynthetic activity of chondrocytes seeded in collagen-glycosaminoglycan matrices. | Tissue engineering 20030201 |
| Teratogen-induced activation of the mitochondrial apoptotic pathway in the yolk sac of day 9 mouse embryos. | Birth defects research. Part A, Clinical and molecular teratology 20030201 |
| Antiapoptotic effect of heat adaptation in cultured cells. | Bulletin of experimental biology and medicine 20030201 |
| Direct and cross-protective effects of heat adaptation in cultured cells. | Bulletin of experimental biology and medicine 20030201 |
| Protein phosphatase 2A (PP2A) regulates interleukin-4-mediated STAT6 signaling. | The Journal of biological chemistry 20030131 |
| H-Ras-specific activation of NF-kappaB protects NIH 3T3 cells against stimulus-dependent apoptosis. | Oncogene 20030130 |
| Mechanisms of regulation of phospholipase D1 by protein kinase Calpha. | The Journal of biological chemistry 20030124 |
| Downregulation of uPA inhibits migration and PI3k/Akt signaling in glioblastoma cells. | Oncogene 20030123 |
| A functional role for nicotine in Bcl2 phosphorylation and suppression of apoptosis. | The Journal of biological chemistry 20030117 |
| Ciliary neurotrophic factor overexpression in neural progenitor cells (ST14A) increases proliferation, metabolic activity, and resistance to stress during differentiation. | Journal of neuroscience research 20030115 |
| Transcriptionally mediated gene targeting of gas1 to glioma cells elicits growth arrest and apoptosis. | Journal of neuroscience research 20030115 |
| Methylglyoxal-bovine serum albumin stimulates tumor necrosis factor alpha secretion in RAW 264.7 cells through activation of mitogen-activating protein kinase, nuclear factor kappaB and intracellular reactive oxygen species formation. | Archives of biochemistry and biophysics 20030115 |
| Angiotensin II AT1 receptor stimulates Na+ -K+ATPase activity through a pathway involving PKC-zeta in rat thyroid cells. | The Journal of physiology 20030115 |
| Connexin mediates gap junction-independent resistance to cellular injury. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030115 |
| Staurosporine-induced apoptosis and hydrogen peroxide-induced necrosis in two human breast cell lines. | British journal of cancer 20030113 |
| Mitochondrial outer membrane permeability change and hypersensitivity to digitonin early in staurosporine-induced apoptosis. | The Journal of biological chemistry 20030110 |
| Protection of insulin receptor substrate-3 from staurosporine-induced apoptosis. | Biochemical and biophysical research communications 20030110 |
| Analysis of protein tyrosine kinase inhibitors in recombinant yeast lacking the ERG6 gene. | Chembiochem : a European journal of chemical biology 20030103 |
| Progesterone induces acrosome reaction in stallion spermatozoa via a protein tyrosine kinase dependent pathway. | Molecular reproduction and development 20030101 |
| Protein kinase C activity, translocation, and selective isoform subcellular redistribution in the rat cerebral cortex after in vitro ischemia. | Journal of neuroscience research 20030101 |
| Natriuretic peptides suppress protein kinase C activity to reduce evoked dopamine efflux from pheochromocytoma (PC12) cells. | Endocrinology 20030101 |
| Bryostatin 1 and UCN-01 potentiate 1-beta-D-arabinofuranosylcytosine-induced apoptosis in human myeloid leukemia cells through disparate mechanisms. | Molecular pharmacology 20030101 |
| Temporal regulation of agonist efficacy at 5-hydroxytryptamine (5-HT)1A and 5-HT 1B receptors. | The Journal of pharmacology and experimental therapeutics 20030101 |
| Novel small molecule inhibitors of caspase-3 block cellular and biochemical features of apoptosis. | The Journal of pharmacology and experimental therapeutics 20030101 |
| Adenosine triphosphate activates mitogen-activated protein kinase in pre-neoplastic and neoplastic ovarian surface epithelial cells. | Biology of reproduction 20030101 |
| Early steps in the oxidative burst induced by cadmium in cultured tobacco cells (BY-2 line). | Journal of experimental botany 20030101 |
| Effect of protein kinase C activation on Na+-H+ exchange in erythrocytes of frog Rana temporaria. | Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20030101 |
| Transient transfection protects PC6-3 cells from apoptosis induced by nerve growth factor deprivation. | Neuroscience 20030101 |
| [Abrogation of radiation-induced G2 arrest and radiosensitization by 7-hydroxystaurosporine (UCN-01) in human nasopharyngeal carcinoma cell line]. | Ai zheng = Aizheng = Chinese journal of cancer 20030101 |
| Physiological apoptotic agents have different effects upon human amnion epithelial and mesenchymal cells. | Placenta 20030101 |
| Protection of mature oligodendrocytes by inhibitors of caspases and calpains. | Neurochemical research 20030101 |
| The role of protein kinase C in modulation of aqueous humor outflow facility. | Experimental eye research 20030101 |
| Beta-adrenergic stimulation of Na(+)-K(+)-2Cl(-) cotransport activity in the rabbit lens. | Experimental eye research 20030101 |
| Bradykinin B2 receptor-mediated proliferation via activation of the Ras/Raf/MEK/MAPK pathway in rat vascular smooth muscle cells. | Journal of biomedical science 20030101 |
| Overexpression of wild-type presenilin 2 or its familial Alzheimer's disease-associated mutant does not induce or increase susceptibility to apoptosis in different cell lines. | Neuroscience 20030101 |
| Characterization of the biosynthetic gene cluster of rebeccamycin from Lechevalieria aerocolonigenes ATCC 39243. | Bioscience, biotechnology, and biochemistry 20030101 |
| Fluorescence anisotropy in pharmacologic screening. | Methods in enzymology 20030101 |
| N-Ac-DEVD-N'-(Polyfluorobenzoyl)-R110: novel cell-permeable fluorogenic caspase substrates for the detection of caspase activity and apoptosis. | Bioconjugate chemistry 20030101 |
| Potentiation of DNA-damage-induced cytotoxicity by G2 checkpoint abrogators. | Current medicinal chemistry. Anti-cancer agents 20030101 |
| Cyclin-dependent kinase modulators studied at the NCI: pre-clinical and clinical studies. | Current medicinal chemistry. Anti-cancer agents 20030101 |
| Involvement of high-density lipoprotein in stimulatory effect of hormones supporting function of the bovine corpus luteum. | Acta veterinaria Hungarica 20030101 |
| Cross-talk among noradrenaline, adenosine and protein kinase C in the mechanisms of ischemic preconditioning in rabbits. | Journal of cardiovascular pharmacology 20030101 |
| [Effects of lysophosphatidylcholine on expression of monocyte chemoattractant protein-1 in glomerular endothelial cells]. | Nihon Jinzo Gakkai shi 20030101 |
| Prolactin signalling in porcine theca cells: the involvement of protein kinases and phosphatases. | Reproduction, fertility, and development 20030101 |
| Integrins regulate neuronal neurotrophin gene expression through effects on voltage-sensitive calcium channels. | Neuroscience 20030101 |
| Effect of tyrosine kinase inhibitors on tyrosine phosphorylation and motility parameters in human sperm. | Archives of andrology 20030101 |
| Human papillomaviruses type 16+ and 18+ cervical carcinoma cells are sensitive to staurosporine-mediated apoptosis. | Biology of the cell 20030101 |
| Phorbol myristate acetate and Bryostatin 1 rescue IFN-gamma inducibility of MHC class II molecules in LS1034 colorectal carcinoma cell line. | Cancer cell international 20030101 |
| Differential responses of human umbilical and coronary artery endothelial cells to apoptosis. | Endothelium : journal of endothelial cell research 20030101 |
| Bench-to-bedside review: severe lactic acidosis in HIV patients treated with nucleoside analogue reverse transcriptase inhibitors. | Critical care (London, England) 20030101 |
| Effect of PKC412, an inhibitor of protein kinase C, on spontaneous metastatic model mice. | Anticancer research 20030101 |
| Studies on neuronal apoptosis in primary forebrain cultures: neuroprotective/anti-apoptotic action of NR2B NMDA antagonists. | Neurotoxicity research 20030101 |
| Characterization of adapt33, a stress-inducible riboregulator. | Gene expression 20030101 |
| Photodynamic inactivation of isolated crayfish neuron requires protein kinase C, PI 3-kinase and Ca2+. | Journal of photochemistry and photobiology. B, Biology 20030101 |
| Involvement of phosphatidic acid in both degranulation and oxidative activity in fMet-Leu-Phe stimulated polymorphonuclear leukocytes. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20030101 |
| Cisplatin-induced ubiquitination of RNA polymerase II large subunit and suppression of induction by 7-hydroxystaurosporine (UCN-01). | Oncology reports 20030101 |
| Epidermal growth factor regulates Ca2+ uptake in primary cultured renal proximal tubule cells: involvement of cAMP, PKC and cPLA2. | Kidney & blood pressure research 20030101 |
| Pituitary adenylate cyclase-activating polypeptide (PACAP)-evoked increase in cyclic AMP production in chick cerebral cortex: lack of a role of the protein kinase C pathway. | Polish journal of pharmacology 20030101 |
| Combined antitumor activity of 7-hydroxystaurosporine (UCN-01) and tamoxifen against human breast carcinoma in vitro and in vivo. | Breast cancer (Tokyo, Japan) 20030101 |
| Nuclear annexin II negatively regulates growth of LNCaP cells and substitution of ser 11 and 25 to glu prevents nucleo-cytoplasmic shuttling of annexin II. | BMC biochemistry 20030101 |
| Replicon size and the dynamics of DNA replication during staurosporine- and vanadate-stimulated endo-S phases in primary roots of Pisum sativum. | Folia histochemica et cytobiologica 20030101 |
| Staurosporine stimulates insulin gene expression via CRE dependent manner. | Nucleic acids research. Supplement (2001) 20030101 |
| Participation of chloroplasts in plant apoptosis. | Bioscience reports 20030101 |
| Mitogen-activated protein kinases in normal and (pre)neoplastic ovarian surface epithelium. | Reproductive biology and endocrinology : RB&E 20030101 |
| Herpes simplex virus UL14 protein blocks apoptosis. | Microbiology and immunology 20030101 |
| A new method for in vitro detection of microbially produced mitochondrial toxins. | Toxicology in vitro : an international journal published in association with BIBRA 20030101 |
| Transforming growth factor-beta 1 induces vascular endothelial growth factor expression in murine proximal tubular epithelial cells. | Nephron. Experimental nephrology 20030101 |
| Effect of epidermal growth factor on phosphate uptake in renal proximal tubule cells: involvement of PKC, MAPK, and cPLA2. | Kidney & blood pressure research 20030101 |
| Role and regulation of p53 in depolarization-induced neuronal death. | Neuroscience 20030101 |
| From antibody insult to fibrosis in neonatal lupus - the heart of the matter. | Arthritis research & therapy 20030101 |
| A potential role for cx43-hemichannels in staurosporin-induced apoptosis. | Cell communication & adhesion 20030101 |
| [Effect of inhibiting protein kinase C on calcium sensitivity of contractile apparatus of vascular smooth muscle during vasospasms of different origins]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20030101 |
| Bioactive natural products from marine invertebrates and associated fungi. | Progress in molecular and subcellular biology 20030101 |
| Corpus luteum regression in the rat--in vivo and in vitro studies of apoptotic mechanisms. | Journal of medicine 20030101 |
| Neuroprotective effects of copper/zinc-dependent superoxide dismutase against a wide variety of death-inducing stimuli and proapoptotic effect of familial amyotrophic lateral sclerosis mutations. | Brain research. Molecular brain research 20021230 |
| NADPH oxidase-dependent oxidation and externalization of phosphatidylserine during apoptosis in Me2SO-differentiated HL-60 cells. Role in phagocytic clearance. | The Journal of biological chemistry 20021220 |
| Gangliosides activate Trk receptors by inducing the release of neurotrophins. | The Journal of biological chemistry 20021220 |
| Regulation of intracellular pH mediates Bax activation in HeLa cells treated with staurosporine or tumor necrosis factor-alpha. | The Journal of biological chemistry 20021220 |
| Role for chloride but not potassium channels in apoptosis in primary rat cortical cultures. | Neuroscience letters 20021213 |
| Nuclear phosphatases and the proteasome in suppression of STAT1 activity in hepatocytes. | Biochemical and biophysical research communications 20021213 |
| Signaling pathways involved in Ca2+- and Pb2+-induced vesicular catecholamine release from rat PC12 cells. | Brain research 20021206 |
| Citicoline increases glutathione redox ratio and reduces caspase-3 activation and cell death in staurosporine-treated SH-SY5Y human neuroblastoma cells. | Brain research 20021206 |
| A nuclear protein tyrosine phosphatase activates p53 and induces caspase-1-dependent apoptosis. | FEBS letters 20021204 |
| alpha1B-Adrenergic receptor phosphorylation and desensitization induced by transforming growth factor-beta. | The Biochemical journal 20021201 |
| Coordinate upregulation of guanylin and uroguanylin expression by hypertonicity in HT29-18-N2 cells. | American journal of physiology. Cell physiology 20021201 |
| Inhibitory interactions between 5-HT3 and P2X channels in submucosal neurons. | American journal of physiology. Gastrointestinal and liver physiology 20021201 |
| Inhibitory effects of cAMP and protein kinase C on meiotic maturation and MAP kinase phosphorylation in porcine oocytes. | Molecular reproduction and development 20021201 |
| Nuclear localisation of cytosolic phospholipase A2-alpha in the EA.hy.926 human endothelial cell line is proliferation dependent and modulated by phosphorylation. | Journal of cell science 20021201 |
| Inhibition of apoptosis in pulmonary endothelial cells by altered pH, mitochondrial function, and ATP supply. | American journal of physiology. Lung cellular and molecular physiology 20021201 |
| Establishment of a triploid V79 cell line from tetraploid cells obtained through polyploidization using K-252a. | Cell proliferation 20021201 |
| Levamisole receptor phosphorylation: effects of kinase antagonists on membrane potential responses in Ascaris suum suggest that CaM kinase and tyrosine kinase regulate sensitivity to levamisole. | The Journal of experimental biology 20021201 |
| Analogs of WIN 62,577 define a second allosteric site on muscarinic receptors. | Molecular pharmacology 20021201 |
| Overexpression of PrPc triggers caspase 3 activation: potentiation by proteasome inhibitors and blockade by anti-PrP antibodies. | Journal of neurochemistry 20021201 |
| Role of specific protein kinase C isozymes in mediating epidermal growth factor, thyrotropin-releasing hormone, and phorbol ester regulation of the rat prolactin promoter in GH4/GH4C1 pituitary cells. | Molecular endocrinology (Baltimore, Md.) 20021201 |
| Bilobalide and neuroprotection. | Pharmacological research 20021201 |
| The novel antimicrotubule agent cryptophycin 52 (LY355703) induces apoptosis via multiple pathways in human prostate cancer cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20021201 |
| Cell death in adult neural stem cells. | Cell death and differentiation 20021201 |
| Fluorescence imaging of mobility shifts: an expression cloning method for identification of cell signaling targets. | Laboratory investigation; a journal of technical methods and pathology 20021201 |
| Mechanical overload-induced apoptosis: a study in cultured neonatal ventricular myocytes and fibroblasts. | Molecular and cellular biochemistry 20021201 |
| IgG-mediated signal transduction in canine mastocytoma-derived cells. | International archives of allergy and immunology 20021201 |
| Stimulation of 14-3-3 protein and its isoform on histamine secretion from permeabilized rat peritoneal mast cells. | Biological & pharmaceutical bulletin 20021201 |
| Partial cleavage of A-type lamins concurs with their total disintegration from the nuclear lamina during apoptosis. | European journal of cell biology 20021201 |
| Rapid uncoupling of serotonin-1A receptors in rat hippocampus by 17beta-estradiol in vitro requires protein kinases A and C. | Neuroendocrinology 20021201 |
| Cloning of the staurosporine biosynthetic gene cluster from Streptomyces sp. TP-A0274 and its heterologous expression in Streptomyces lividans. | The Journal of antibiotics 20021201 |
| A high-throughput, nonisotopic, competitive binding assay for kinases using nonselective inhibitor probes (ED-NSIP). | Journal of biomolecular screening 20021201 |
| Structural basis for Chk1 inhibition by UCN-01. | The Journal of biological chemistry 20021129 |
| Tamoxifen-induced growth arrest and apoptosis in pituitary tumor cells in vitro via a protein kinase C-independent pathway. | Cancer letters 20021128 |
| A microarray-based, integrated approach to identify novel regulators of cancer drug response and apoptosis. | Oncogene 20021128 |
| Signaling pathways for TNF production induced by human aminoacyl-tRNA synthetase-associating factor, p43. | Cytokine 20021124 |
| Oligomycin, inhibitor of the F0 part of H+-ATP-synthase, suppresses the TNF-induced apoptosis. | Oncogene 20021121 |
| Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20021115 |
| Src activation regulates anoikis in human colon tumor cell lines. | Oncogene 20021107 |
| Apoptosis-specific protein (ASP 45 kDa) is distinct from human Apg5, the homologue of the yeast autophagic gene apg5. | FEBS letters 20021106 |
| Interleukin-1beta-induced cyclooxygenase-2 expression is mediated through activation of p42/44 and p38 MAPKS, and NF-kappaB pathways in canine tracheal smooth muscle cells. | Cellular signalling 20021101 |
| Excitatory amino acid-elicited tonic convulsions in mice and N-methyl-D-aspartate receptor activation: role of Ca(2+) influx and involvement of intracellular Ca(2+)-dependent biochemical processes. | Pharmacology 20021101 |
| Regulation of alternative oxidase gene expression in soybean. | Plant molecular biology 20021101 |
| Combined treatment with the checkpoint abrogator UCN-01 and MEK1/2 inhibitors potently induces apoptosis in drug-sensitive and -resistant myeloma cells through an IL-6-independent mechanism. | Blood 20021101 |
| Phorbol ester stimulates a protein kinase C-mediated agatoxin-TK-sensitive calcium permeability pathway in human red blood cells. | Blood 20021101 |
| The R1 subunit of herpes simplex virus ribonucleotide reductase protects cells against apoptosis at, or upstream of, caspase-8 activation. | The Journal of general virology 20021101 |
| Caspase-independent phosphatidylserine exposure during apoptosis of primary T lymphocytes. | Journal of immunology (Baltimore, Md. : 1950) 20021101 |
| Inhibition of prostaglandin E(2) production by taiwanin C isolated from the root of Acanthopanax chiisanensis and the mechanism of action. | Biochemical pharmacology 20021101 |
| Novel membrane traffic steps regulate the exocytosis of the Menkes disease ATPase. | Human molecular genetics 20021101 |
| The effects of lidocaine on the activity of glutamate transporter EAAT3: the role of protein kinase C and phosphatidylinositol 3-kinase. | Anesthesia and analgesia 20021101 |
| Staurosporine mobilizes Ca(2+) from secretory granules by inhibiting protein kinase C in rat submandibular acinar cells. | Journal of dental research 20021101 |
| Induction of marked apoptosis in mammalian cancer cell lines by antisense DNA treatment to abolish expression of DENN (differentially expressed in normal and neoplastic cells). | Molecular carcinogenesis 20021101 |
| Bisindolylmaleimide I and V inhibit necrosis induced by oxidative stress in a variety of cells including neurons. | Neuroscience research 20021101 |
| Cell shape change precedes staurosporine-induced stabilization and accumulation of p27kip1. | Experimental cell research 20021101 |
| Antitumor activity of UCN-01 in carcinomas of the head and neck is associated with altered expression of cyclin D3 and p27(KIP1). | Clinical cancer research : an official journal of the American Association for Cancer Research 20021101 |
| Staurosporine-induced cleavage of alpha-smooth muscle actin during myofibroblast apoptosis. | The Journal of investigative dermatology 20021101 |
| Neuroprotective effect of apolipoprotein E against ischemia. | Annals of the New York Academy of Sciences 20021101 |
| [Caspase-3-mediated alpha-smooth muscle actin cleavage during staurosporine-induced myofibroblast apoptosis]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20021101 |
| Participation of various kinases in staurosporine induced apoptosis of RAW 264.7 cells. | The Journal of pharmacy and pharmacology 20021101 |
| Protein kinase C regulation of rat jejunal transport system: mechanisms involved in lactate movement. | Experimental physiology 20021101 |
| Modulation of steroid hydroxylase activity in stably transfected V79MZh11B1 and V79MZh11B2 cells by PKC and PKD inhibitors. | Endocrine research 20021101 |
| A FRET-based assay platform for ultra-high density drug screening of protein kinases and phosphatases. | Assay and drug development technologies 20021101 |
| The different responses of rat glutamate transporter type 2 and its mutant (tyrosine 403 to histidine) activity to volatile anesthetics and activation of protein kinase C. | Brain research 20021025 |
| Interaction between alpha2-autoreceptors and receptors mediating the effects of angiotensin II and bradykinin in the heart of newborn rats. | European journal of pharmacology 20021025 |
| Synthesis and kinase inhibitory activity of 3'-(S)-epi-K-252a. | Bioorganic & medicinal chemistry letters 20021021 |
| UCN-01 inhibits p53 up-regulation and abrogates gamma-radiation-induced G(2)-M checkpoint independently of p53 by targeting both of the checkpoint kinases, Chk2 and Chk1. | Cancer research 20021015 |
| Distinct BAG-1 isoforms have different anti-apoptotic functions in BAG-1-transfected C33A human cervical carcinoma cell line. | Oncogene 20021010 |
| Apoptotic mechanisms in T47D and MCF-7 human breast cancer cells. | British journal of cancer 20021007 |
| Protein kinase C inhibitors decrease endothelin ET(B) receptor mRNA expression and contraction during organ culture of rat mesenteric artery. | European journal of pharmacology 20021004 |
| Staurosporine induces endothelial cell apoptosis via focal adhesion kinase dephosphorylation and focal adhesion disassembly independent of focal adhesion kinase proteolysis. | The Biochemical journal 20021001 |
| Biphasic translocation of Bax to mitochondria. | The Biochemical journal 20021001 |
| D-erythro-N,N-dimethylsphingosine inhibits bFGF-induced proliferation of cerebral, aortic and coronary smooth muscle cells. | Atherosclerosis 20021001 |
| The in vitro effects of Pb acetate on NO production by C6 glial cells. | Toxicology in vitro : an international journal published in association with BIBRA 20021001 |
| NCX-4016, a nitric oxide-releasing aspirin, protects endothelial cells against apoptosis by modulating mitochondrial function. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021001 |
| Localization of IP in rabbit kidney and functional role of the PGI(2)/IP system in cortical collecting duct. | American journal of physiology. Renal physiology 20021001 |
| Hyperosmotic urea activates basolateral NHE in proximal tubule from P-gp null and wild-type mice. | American journal of physiology. Renal physiology 20021001 |
| Cytochrome c activates K+ channels before inducing apoptosis. | American journal of physiology. Cell physiology 20021001 |
| Antitumorigenic and antiinsulinogenic effects of calcitriol on insulinoma cells and solid beta-cell tumors. | Endocrinology 20021001 |
| IL-1 beta potentiates heat-activated currents in rat sensory neurons: involvement of IL-1RI, tyrosine kinase, and protein kinase C. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021001 |
| A simplified protocol for apoptosis assay by DNA content analysis. | BioTechniques 20021001 |
| Cholinergic activation of glucose transport in bovine chromaffin cells involves calmodulin and protein kinase Czeta signaling. | Annals of the New York Academy of Sciences 20021001 |
| Vascular endothelial growth factor gene expression regulated by protein kinase C pathway in endothelial cells during hypoxia. | Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering 20021001 |
| Lysophosphatidylcholine alters enterocyte monolayer permeability via a protein kinase C/Ca2+ mechanism. | Pediatric surgery international 20021001 |
| Differential sensitivity of endothelial cells of various species to apoptosis induced by gene transfer of Fas ligand: role of FLIP levels. | Molecular medicine (Cambridge, Mass.) 20021001 |
| A novel indolocarbazole, ICP-1, abrogates DNA damage-induced cell cycle arrest and enhances cytotoxicity: similarities and differences to the cell cycle checkpoint abrogator UCN-01. | Molecular cancer therapeutics 20021001 |
| Cyclin-dependent kinases as new targets for the prevention and treatment of cancer. | Hematology/oncology clinics of North America 20021001 |
| A versatile high-throughput screen for inhibitors of lipid kinase activity: development of an immobilized phospholipid plate assay for phosphoinositide 3-kinase gamma. | Journal of biomolecular screening 20021001 |
| Trafficking of ganglioside GD3 to mitochondria by tumor necrosis factor-alpha. | The Journal of biological chemistry 20020927 |
| Analysis of the life cycle of stat6. Continuous cycling of STAT6 is required for IL-4 signaling. | The Journal of biological chemistry 20020927 |
| Selective NR2B NMDA receptor antagonists are protective against staurosporine-induced apoptosis. | European journal of pharmacology 20020927 |
| Evaluation of 2-deoxy-D-glucose as a chemotherapeutic agent: mechanism of cell death. | British journal of cancer 20020923 |
| Phorbol ester-regulated oligomerization of diacylglycerol kinase delta linked to its phosphorylation and translocation. | The Journal of biological chemistry 20020920 |
| Role of ubiquilin associated with protein-disulfide isomerase in the endoplasmic reticulum in stress-induced apoptotic cell death. | The Journal of biological chemistry 20020920 |
| Phospholipase C-gamma modulates epithelial tight junction permeability through hyperphosphorylation of tight junction proteins. | The Journal of biological chemistry 20020920 |
| Lipophilic fraction of Panax ginseng induces neuronal differentiation of PC12 cells and promotes neuronal survival of rat cortical neurons by protein kinase C dependent manner. | Brain research 20020920 |
| Human cardiac inwardly-rectifying K+ channel Kir(2.1b) is inhibited by direct protein kinase C-dependent regulation in human isolated cardiomyocytes and in an expression system. | Circulation 20020917 |
| Exogenous smac induces competence and permits caspase activation in sympathetic neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020915 |
| Caspase activation of mammalian sterile 20-like kinase 3 (Mst3). Nuclear translocation and induction of apoptosis. | The Journal of biological chemistry 20020913 |
| Different protein kinase families are activated by osmotic stresses in Arabidopsis thaliana cell suspensions. Involvement of the MAP kinases AtMPK3 and AtMPK6. | FEBS letters 20020911 |
| Effect of Bacillus anthracis lethal toxin on human peripheral blood mononuclear cells. | FEBS letters 20020911 |
| Staurosporine-induced G(1) arrest in cancer cells depends on an intact pRB but is independent of p16 status. | Cancer letters 20020908 |
| Dynamitin controls Beta 2 integrin avidity by modulating cytoskeletal constraint on integrin molecules. | The Journal of biological chemistry 20020906 |
| Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility. | Circulation research 20020906 |
| Anticancer-drug-induced apoptotic cell death in leukemia cells is associated with proteolysis of beta-catenin. | Leukemia research 20020901 |
| Involvement of HB-EGF and EGF receptor transactivation in TGF-beta-mediated fibronectin expression in mesangial cells. | Kidney international 20020901 |
| Characterization and purification of truncated human Rho-kinase II expressed in Sf-21 cells. | Archives of biochemistry and biophysics 20020901 |
| L-Carnitine: a potential treatment for blocking apoptosis and preventing skeletal muscle myopathy in heart failure. | American journal of physiology. Cell physiology 20020901 |
| Inhibition of cyclin-dependent kinase 2 by the Chk1-Cdc25A pathway during the S-phase checkpoint activated by fludarabine: dysregulation by 7-hydroxystaurosporine. | Molecular pharmacology 20020901 |
| Protein kinase mediated upregulation of endothelin A, endothelin B and 5-hydroxytryptamine 1B/1D receptors during organ culture in rat basilar artery. | British journal of pharmacology 20020901 |
| Regulation of granulosa cell-derived insulin-like growth factor binding proteins (IGFBPs): role for protein kinase-C in the pre- and posttranslational modulation of IGFBP-4 and IGFBP-5. | Biology of reproduction 20020901 |
| Xenogeneic human NK cytotoxicity against porcine endothelial cells is perforin/granzyme B dependent and not inhibited by Bcl-2 overexpression. | Xenotransplantation 20020901 |
| Involvement of both extracellular signal-regulated kinase and c-jun N-terminal kinase pathways in the 12-O-tetradecanoylphorbol-13-acetate-induced upregulation of p21(Cip1) in colon cancer cells. | Molecular carcinogenesis 20020901 |
| TrkA as a life and death receptor: receptor dose as a mediator of function. | Cancer research 20020901 |
| Gene transfer of glial cell-derived neurotrophic factor and cardiotrophin-1 protects PC12 cells from injury: involvement of the phosphatidylinositol 3-kinase and mitogen-activated protein kinase kinase pathways. | Journal of neuroscience research 20020901 |
| Protein phosphorylation regulates actomyosin-driven vesicle movement in cell extracts isolated from the green algae, Chara corallina. | Cell motility and the cytoskeleton 20020901 |
| krox-20/egr-2 is up-regulated following non-specific and homophilic adhesion in rat macrophages. | Immunology 20020901 |
| Activation of phosphatidylinositol 3-kinase is important for erythropoietin-induced erythropoiesis from CD34(+) hematopoietic progenitor cells. | Experimental hematology 20020901 |
| Characterization of early, chitin-induced gene expression in Arabidopsis. | Molecular plant-microbe interactions : MPMI 20020901 |
| Cytochrome c release precedes mitochondrial membrane potential loss in cerebellar granule neuron apoptosis: lack of mitochondrial swelling. | Journal of neurochemistry 20020901 |
| The antidepressant tianeptine persistently modulates glutamate receptor currents of the hippocampal CA3 commissural associational synapse in chronically stressed rats. | The European journal of neuroscience 20020901 |
| Anti-apoptotic properties of Ginkgo biloba extract EGb 761 in differentiated PC12 cells. | Cellular and molecular biology (Noisy-le-Grand, France) 20020901 |
| Apoptotic response to photodynamic therapy versus the Bcl-2 antagonist HA14-1. | Photochemistry and photobiology 20020901 |
| Threonine 308 within a putative casein kinase 2 site of the cytoplasmic tail of leukotriene B(4) receptor (BLT1) is crucial for ligand-induced, G-protein-coupled receptor-specific kinase 6-mediated desensitization. | The Journal of biological chemistry 20020830 |
| Picrosides I and II, selective enhancers of the mitogen-activated protein kinase-dependent signaling pathway in the action of neuritogenic substances on PC12D cells. | Life sciences 20020830 |
| Mitochondrial targeted cyclophilin D protects cells from cell death by peptidyl prolyl isomerization. | The Journal of biological chemistry 20020823 |
| A pro-apoptotic effect of the CDK inhibitor p57(Kip2) on staurosporine-induced apoptosis in HeLa cells. | Biochemical and biophysical research communications 20020823 |
| Origins and consequences of mitochondrial decline in nucleated erythrocytes. | Biochimica et biophysica acta 20020819 |
| Platelet formation is the consequence of caspase activation within megakaryocytes. | Blood 20020815 |
| Intestinal ischemia preconditions myocardium: role of protein kinase C and mitochondrial K(ATP) channel. | Cardiovascular research 20020815 |
| Identification of orally active, potent, and selective 4-piperazinylquinazolines as antagonists of the platelet-derived growth factor receptor tyrosine kinase family. | Journal of medicinal chemistry 20020815 |
| Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress. | Journal of neuroscience research 20020815 |
| Characterization of PDK2 activity against protein kinase B gamma. | Biochemistry 20020813 |
| Interplay between calcium, diacylglycerol, and phosphorylation in the spatial and temporal regulation of PKCalpha-GFP. | The Journal of biological chemistry 20020809 |
| Alteration of cellular phosphorylation state affects vitamin D receptor-mediated CYP3A4 mRNA induction in Caco-2 cells. | Biochemical and biophysical research communications 20020809 |
| 7-hydroxystaurosporine (UCN-01) and ionizing radiation combine to inhibit the growth of Bcl-2-overexpressing U937 leukemia cells through a non-apoptotic mechanism. | International journal of oncology 20020801 |
| T cell proliferation induced by autologous non-T cells is a response to apoptotic cells processed by dendritic cells. | Journal of immunology (Baltimore, Md. : 1950) 20020801 |
| Polo-like kinase-1 is a pivotal regulator of microtubule assembly during mouse oocyte meiotic maturation, fertilization, and early embryonic mitosis. | Biology of reproduction 20020801 |
| Ceramide-induced apoptosis of D283 medulloblastoma cells requires mitochondrial respiratory chain activity but occurs independently of caspases and is not sensitive to Bcl-xL overexpression. | Journal of neurochemistry 20020801 |
| Protective effects of docosahexaenoic acid in staurosporine-induced apoptosis: involvement of phosphatidylinositol-3 kinase pathway. | Journal of neurochemistry 20020801 |
| The Poly(ADP-ribose) polymerase-1-regulated endonuclease DNAS1L3 is required for etoposide-induced internucleosomal DNA fragmentation and increases etoposide cytotoxicity in transfected osteosarcoma cells. | Cancer research 20020801 |
| Hematologic malignancies: new developments and future treatments. | Seminars in oncology 20020801 |
| Expression of 150-kd oxygen-regulated protein in the hippocampus suppresses delayed neuronal cell death. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020801 |
| Bcl2-negative MCF7 cells overexpress p53: implications for the cell cycle and sensitivity to cytotoxic drugs. | Cancer chemotherapy and pharmacology 20020801 |
| Activation of angiotensin II type I receptor promotes protein kinase C translocation and cell proliferation in human cultured breast epithelial cells. | The Journal of endocrinology 20020801 |
| Dual role of protein kinase C on mitogen-activated protein kinase activation and human keratinocyte proliferation. | Experimental dermatology 20020801 |
| Functional analysis of water channels in barley roots. | Plant & cell physiology 20020801 |
| Amine fluoride gel affects the viability and the generation of superoxide anions in human polymorphonuclear leukocytes: an in vitro study. | European journal of oral sciences 20020801 |
| Pseudolaric acid analogs as a new class of peroxisome proliferator-activated receptor agonists. | Planta medica 20020801 |
| Mechanism of superoxide anion production by hepatic sinusoidal endothelial cells and Kupffer cells during short-term ethanol perfusion in the rat. | Liver 20020801 |
| Dieldrin induces human neutrophil superoxide production via protein kinases C and tyrosine kinases. | Human & experimental toxicology 20020801 |
| A novel method for monitoring response to chemotherapy based on the detection of circulating cancer cells: a case report. | Journal of chemotherapy (Florence, Italy) 20020801 |
| Phosphatidylserine peroxidation/externalization during staurosporine-induced apoptosis in HL-60 cells. | FEBS letters 20020731 |
| Examination of the kinetic mechanism of mitogen-activated protein kinase activated protein kinase-2. | Biochimica et biophysica acta 20020729 |
| Abrogation of the radiation-induced G2 checkpoint by the staurosporine derivative UCN-01 is associated with radiosensitisation in a subset of colorectal tumour cell lines. | British journal of cancer 20020729 |
| Silkworm hemolymph as a potent inhibitor of apoptosis in Sf9 cells. | Biochemical and biophysical research communications 20020726 |
| K252a inhibits the oncogenic properties of Met, the HGF receptor. | Oncogene 20020725 |
| Abrogation of the S phase DNA damage checkpoint results in S phase progression or premature mitosis depending on the concentration of 7-hydroxystaurosporine and the kinetics of Cdc25C activation. | The Journal of biological chemistry 20020719 |
| Translocation of the classic protein kinase C isoforms in porcine oocytes: implications of protein kinase C involvement in the regulation of nuclear activity and cortical granule exocytosis. | Experimental cell research 20020715 |
| Targeting the cell cycle for cancer therapy. | British journal of cancer 20020715 |
| Induction of cyclooxygenase-2 by staurosporine through the activation of nuclear factor for IL-6 (NF-IL6) and activator protein 2 (AP2) in an osteoblast-like cell line. | Biochemical pharmacology 20020715 |
| Modulation by PKA of the hyperpolarization-activated current (Ih) in cultured rat olfactory receptor neurons. | The Journal of membrane biology 20020715 |
| Disparity between ionic mediators of volume regulation and apoptosis in N1E 115 mouse neuroblastoma cells. | Brain research 20020712 |
| Staurosporine enhances the expression of tissue inhibitor of metalloproteinase-1 in human prostate cancer cells. | Biochemical and biophysical research communications 20020712 |
| Single-cell fluorescence resonance energy transfer analysis demonstrates that caspase activation during apoptosis is a rapid process. Role of caspase-3. | The Journal of biological chemistry 20020705 |
| Protein kinase C-dependent inhibition of the lysosomal degradation of endocytosed proteins in rat hepatocytes. | Cellular signalling 20020701 |
| Constitutive caspase-like machinery executes programmed cell death in plant cells. | Cell death and differentiation 20020701 |
| Defective Bax activation in Hodgkin B-cell lines confers resistance to staurosporine-induced apoptosis. | Cell death and differentiation 20020701 |
| The unique property of the CC chemokine regakine-1 to synergize with other plasma-derived inflammatory mediators in neutrophil chemotaxis does not reside in its NH2-terminal structure. | Molecular pharmacology 20020701 |
| Control of cortical interneuron migration by neurotrophins and PI3-kinase signaling. | Development (Cambridge, England) 20020701 |
| 7-Hydroxystaurosporine (UCN-01) preferentially sensitizes cells with a disrupted TP53 to gamma radiation in lung cancer cell lines. | Radiation research 20020701 |
| Hepatoprotection with tauroursodeoxycholate and beta muricholate against taurolithocholate induced cholestasis: involvement of signal transduction pathways. | Gut 20020701 |
| Activation of protein kinase C induces mitogen-activated protein kinase dephosphorylation and pronucleus formation in rat oocytes. | Biology of reproduction 20020701 |
| Capacitation induces cyclic adenosine 3',5'-monophosphate-dependent, but apoptosis-unrelated, exposure of aminophospholipids at the apical head plasma membrane of boar sperm cells. | Biology of reproduction 20020701 |
| Sevoflurane increases glucose transport in skeletal muscle cells. | Anesthesia and analgesia 20020701 |
| Activation of protein kinase C sensitizes human VR1 to capsaicin and to moderate decreases in pH at physiological temperatures in Xenopus oocytes. | Pain 20020701 |
| Gamma-aminobutyric acid transporter (BGT-1) expressed in human astrocytoma U373 MG cells: pharmacological and molecular characterization and phorbol ester-induced inhibition. | Journal of neuroscience research 20020701 |
| Treatment of peripheral blood with staurosporine increases detection of circulating carcinoembryonic antigen positive tumor cells. | International journal of cancer 20020701 |
| Hyperosmotic stimuli inhibit VCAM-1 expression in cultured endothelial cells via effects on interferon regulatory factor-1 expression and activity. | European journal of immunology 20020701 |
| Expression and differential processing of caspases 6 and 7 in relation to specific epileptiform EEG patterns following limbic seizures. | Neurobiology of disease 20020701 |
| Isoflurane pretreatment inhibits cytokine-induced cell death in cultured rat smooth muscle cells and human endothelial cells. | Anesthesiology 20020701 |
| Activation of Raf-1/MEK-1/2/p42/44(MAPK) cascade alone is sufficient to uncouple LDL receptor expression from cell growth. | Molecular and cellular biochemistry 20020701 |
| Effect of protein kinase C on multidrug resistance of multidrug-resistant colorectal cancer LoVo/Adr cells. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20020701 |
| Modulation of neurotransmitter release induced by brain-derived neurotrophic factor in rat brain striatal slices in vitro. | Brain research 20020621 |
| Attachment of the PSGL-1 cytoplasmic domain to the actin cytoskeleton is essential for leukocyte rolling on P-selectin. | Blood 20020615 |
| Rho-dependent and -independent activation mechanisms of ezrin/radixin/moesin proteins: an essential role for polyphosphoinositides in vivo. | Journal of cell science 20020615 |
| 7-Ketocholesterol and staurosporine induce opposite changes in intracellular pH, associated with distinct types of cell death in ECV304 cells. | Archives of biochemistry and biophysics 20020615 |
| Critical requirement of BAX for manifestation of apoptosis induced by multiple stimuli in human epithelial cancer cells. | Cancer research 20020615 |
| Phosphorylation-dependent differences in the activation properties of distal and proximal dendritic Na+ channels in rat CA1 hippocampal neurons. | The Journal of physiology 20020615 |
| Cell death and mechanoprotection by filamin a in connective tissues after challenge by applied tensile forces. | The Journal of biological chemistry 20020614 |
| Apolipoprotein E4 potentiates amyloid beta peptide-induced lysosomal leakage and apoptosis in neuronal cells. | The Journal of biological chemistry 20020614 |
| Maspin sensitizes breast carcinoma cells to induced apoptosis. | Oncogene 20020613 |
| Transforming growth factor-beta1 regulation of growth zone chondrocytes is mediated by multiple interacting pathways. | Biochimica et biophysica acta 20020612 |
| Release of snRNP and RNA from transcription sites in adenovirus-infected cells. | Experimental cell research 20020610 |
| A novel, extraneuronal role for cyclin-dependent protein kinase 5 (CDK5): modulation of cAMP-induced apoptosis in rat leukemia cells. | The Journal of biological chemistry 20020607 |
| Studies on the role of calcium in the 5-HT-stimulated release of glutamate from C6 glioma cells. | European journal of pharmacology 20020607 |
| Estrogen-induced proliferation of urothelial cells is modulated by nerve growth factor. | American journal of physiology. Renal physiology 20020601 |
| 7-Hydroxystaurosporine-induced apoptosis in 9L glioma cells provides an effective antigen source for dendritic cells and yields a potent vaccine strategy in an intracranial glioma model. | Neurosurgery 20020601 |
| Signal transduction controlling the blue- and red-light mediated gene expression of S-adenosylmethionine decarboxylase in Pharbitis nil. | Journal of experimental botany 20020601 |
| An early increase in the disialoganglioside GD3 contributes to the development of neuronal apoptosis in culture. | Cell death and differentiation 20020601 |
| Induction of apoptosis by nitric oxide in macrophages is independent of apoptotic volume decrease. | Cell death and differentiation 20020601 |
| Teratogen-induced activation of caspase-9 and the mitochondrial apoptotic pathway in early postimplantation mouse embryos. | Toxicology and applied pharmacology 20020601 |
| Reduction of trophic support enhances apoptosis in PC12 cells expressing Alzheimer's APP mutation and sensitizes cells to staurosporine-induced cell death. | Journal of molecular neuroscience : MN 20020601 |
| Transglutaminase overexpression sensitizes neuronal cell lines to apoptosis by increasing mitochondrial membrane potential and cellular oxidative stress. | Journal of neurochemistry 20020601 |
| Divergence of angiogenic and vascular permeability signaling by VEGF: inhibition of protein kinase C suppresses VEGF-induced angiogenesis, but promotes VEGF-induced, NO-dependent vascular permeability. | Arteriosclerosis, thrombosis, and vascular biology 20020601 |
| PKC and Raf-1 inhibition-related apoptotic signalling in N2a cells. | Journal of neurochemistry 20020601 |
| Yeast RSC function is required for organization of the cellular cytoskeleton via an alternative PKC1 pathway. | Genetics 20020601 |
| Participation of the arachidonic acid cascade pathway in macrophage binding/uptake of oxidized low density lipoprotein. | Biological & pharmaceutical bulletin 20020601 |
| Factor VIIa induced release of von Willebrand factor from human umbilical vein endothelial cells by a tyrosine kinase dependent pathway. | Thrombosis and haemostasis 20020601 |
| A protein kinase C inhibitor induces phenotypic reversion of ras-transformed pancreatic cancer cells and cooperatively blocks tumor cell proliferation with an anti- ras peptide. | Cancer chemotherapy and pharmacology 20020601 |
| Regulation of matrix metalloproteinase production by cytokines, pharmacological agents and periodontal pathogens in human periodontal ligament fibroblast cultures. | Journal of periodontal research 20020601 |
| Inhibition of mutant FLT3 receptors in leukemia cells by the small molecule tyrosine kinase inhibitor PKC412. | Cancer cell 20020601 |
| Involvement of chloroplasts in the programmed death of plant cells. | Biochemistry. Biokhimiia 20020601 |
| Detection of NGF-receptors TrkA and p75NTR in human tumor cell lines and effect of NGF on the growth characteristic of the UT-7/EPO cell line. | Journal of experimental & clinical cancer research : CR 20020601 |
| Effects of volatile anesthetics on glutamate transporter, excitatory amino acid transporter type 3: the role of protein kinase C. | Anesthesiology 20020601 |
| Caspase inhibition protects nerve terminals from in vitro degradation. | Neurochemical research 20020601 |
| [Potentiation of radiosensitivity by staurosporine associated with abrogation of G2 phase arrest]. | Yao xue xue bao = Acta pharmaceutica Sinica 20020601 |
| Lateral dimerization of the E-cadherin extracellular domain is necessary but not sufficient for adhesive activity. | The Journal of biological chemistry 20020531 |
| The catalytic subunits of IkappaB kinase, IKK-1 and IKK-2, contain non-equivalent active sites when expressed as homodimers. | Biochemical and biophysical research communications 20020524 |
| Ca(2+)-dependent and -independent Cl(-) secretion stimulated by the nitric oxide donor, GEA 3162, in rat colonic epithelium. | European journal of pharmacology 20020524 |
| Increased K+ efflux and apoptosis induced by the potassium channel modulatory protein KChAP/PIAS3beta in prostate cancer cells. | The Journal of biological chemistry 20020517 |
| Evaluation of the role of phosphatidylserine translocase activity in ABCA1-mediated lipid efflux. | The Journal of biological chemistry 20020517 |
| Transforming growth factor-beta 1 increases bad phosphorylation and protects neurons against damage. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020515 |
| Expression, proteolysis and activation of caspases 6 and 7 during rat C6 glioma cell apoptosis. | Neuroscience letters 20020510 |
| MPP+ increases alpha-synuclein expression and ERK/MAP-kinase phosphorylation in human neuroblastoma SH-SY5Y cells. | Brain research 20020510 |
| Resistance of mitochondrial DNA-deficient cells to TRAIL: role of Bax in TRAIL-induced apoptosis. | Oncogene 20020509 |
| Protection of myocytes from hypoxia-reoxygenation injury by nitric oxide is mediated by modulation of transforming growth factor-beta1. | Circulation 20020507 |
| Caspase-mediated parkin cleavage in apoptotic cell death. | The Journal of biological chemistry 20020503 |
| Galectin-3 translocates to the perinuclear membranes and inhibits cytochrome c release from the mitochondria. A role for synexin in galectin-3 translocation. | The Journal of biological chemistry 20020503 |
| Release of cytochrome c into the extracellular space contributes to neuronal apoptosis induced by staurosporine. | Brain research 20020503 |
| The effect of an HIV-1 viral protease inhibitor on staurosporine-induced apoptosis in immortalized mesangial cells. | Sao Paulo medical journal = Revista paulista de medicina 20020502 |
| Human breast cancer MCF-7 cell line contains inherently drug-resistant subclones with distinct genotypic and phenotypic features. | International journal of oncology 20020501 |
| Characterization of the increase in bone 66 kDa protein component with healing rat fractures: stimulatory effect of zinc. | International journal of molecular medicine 20020501 |
| Protein kinase-dependent and Ca(2+)-independent cAMP inhibition of ANP release in beating rabbit atria. | American journal of physiology. Regulatory, integrative and comparative physiology 20020501 |
| Mechanism of staurosporine-induced apoptosis in murine hepatocytes. | American journal of physiology. Gastrointestinal and liver physiology 20020501 |
| 2001 Warkany lecture: to die or not to die, the role of apoptosis in normal and abnormal mammalian development. | Teratology 20020501 |
| Fas, ceramide and serum withdrawal induce apoptosis via a common pathway in a type II Jurkat cell line. | Cell death and differentiation 20020501 |
| Tissue transglutaminase differentially modulates apoptosis in a stimuli-dependent manner. | Journal of neurochemistry 20020501 |
| Phosphatidylinositol 3-kinase regulates PMA-induced differentiation and superoxide production in HL-60 cells. | Immunopharmacology and immunotoxicology 20020501 |
| Protein kinase C regulation of rat jejunal transport systems: mechanisms involved in bicarbonate absorption. | Experimental physiology 20020501 |
| Generation of reactive oxygen species in blood platelets. | Platelets 20020501 |
| Effect of chronic treatment with the protein kinase C inhibitor staurosporine on the acquisition and expression of contextual fear conditioning. | European journal of pharmacology 20020426 |
| Antiapoptotic activity of the free caspase recruitment domain of procaspase-9: a novel endogenous rescue pathway in cell death. | The Journal of biological chemistry 20020419 |
| Transendothelial migration of leukocytes and signalling mechanisms in response to the neuropeptide secretoneurin. | Regulatory peptides 20020415 |
| Protective effect of apolipoprotein E against ischemic neuronal injury is mediated through antioxidant action. | Journal of neuroscience research 20020415 |
| Hyaluronidases and CD44 undergo differential modulation during chondrogenesis. | Biochemical and biophysical research communications 20020412 |
| Pathways of induction of peroxiredoxin I expression in osteoblasts: roles of p38 mitogen-activated protein kinase and protein kinase C. | The Journal of biological chemistry 20020405 |
| Apoptotic release of histones from nucleosomes. | The Journal of biological chemistry 20020405 |
| Calyculin A-induced endothelial cell shape changes are independent of [Ca(2+)](i) elevation and may involve actin polymerization. | Biochimica et biophysica acta 20020403 |
| Phosphorylation of the salivary Na(+)-K(+)-2Cl(-) cotransporter. | American journal of physiology. Cell physiology 20020401 |
| Hyperosmotic mannitol activates basolateral NHE in proximal tubule from P-glycoprotein null mice. | American journal of physiology. Renal physiology 20020401 |
| Adducin in platelets: activation-induced phosphorylation by PKC and proteolysis by calpain. | Blood 20020401 |
| The mutual regulation of arginine-vasopressin and PTHrP secretion in dissociated supraoptic neurons. | Endocrinology 20020401 |
| Cyclophilin-A is involved in excitotoxin-induced caspase activation in rat neuronal B50 cells. | The Biochemical journal 20020401 |
| Prompt inhibition of fMLP-induced Ca2+ mobilization by parenteral lipid emulsions in human neutrophils. | Journal of lipid research 20020401 |
| Protein kinase Mzeta is necessary and sufficient for LTP maintenance. | Nature neuroscience 20020401 |
| Activation of mitochondrial ATP-dependent potassium channels protects neurons against ischemia-induced death by a mechanism involving suppression of Bax translocation and cytochrome c release. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020401 |
| Desensitization of group I metabotropic glutamate receptors in rat sympathetic neurons. | Journal of neurophysiology 20020401 |
| Type I interferon gene transfer sensitizes melanoma cells to apoptosis via a target activity on mitochondrial function. | The American journal of pathology 20020401 |
| Mechanically stimulated TCH3 gene expression in Arabidopsis involves protein phosphorylation and EIN6 downstream of calcium. | Plant physiology 20020401 |
| Complestatin antagonizes the AMPA/kainate-induced neurotoxicity in cultured chick telencephalic neurons. | Neurochemical research 20020401 |
| Inhibition of spontaneous acetylcholine secretion by 2-chloroadenosine as revealed by a protein kinase inhibitor at the mouse neuromuscular junction. | British journal of pharmacology 20020401 |
| Stimulation of protein kinase B and p70 S6 kinase by the histamine H1 receptor in DDT1MF-2 smooth muscle cells. | British journal of pharmacology 20020401 |
| T and B leukemic cell lines exhibit different requirements for cell death: correlation between caspase activation, DFF40/DFF45 expression, DNA fragmentation and apoptosis in T cell lines but not in Burkitt's lymphoma. | Leukemia 20020401 |
| PTEN augments staurosporine-induced apoptosis in PTEN-null Ishikawa cells by downregulating PI3K/Akt signaling pathway. | Cell death and differentiation 20020401 |
| Antitumor activity of benzamide riboside in vitro and in vivo. | Current medicinal chemistry 20020401 |
| Chlamydia pneumoniae inhibits apoptosis in human epithelial and monocyte cell lines. | Scandinavian journal of immunology 20020401 |
| Pharmacological modulation of carcinoembryonic antigen in human cancer cells: studies with staurosporine. | International immunopharmacology 20020401 |
| 7,8-Dihydroneopterin induces apoptosis of Jurkat T-lymphocytes via a Bcl-2-sensitive pathway. | European journal of cell biology 20020401 |
| Protein kinases--the major drug targets of the twenty-first century? | Nature reviews. Drug discovery 20020401 |
| Seventy-two hour continuous infusion flavopiridol in relapsed and refractory mantle cell lymphoma. | Leukemia & lymphoma 20020401 |
| [Effects of TNF-alpha or mmLDL on PAI-1 expression in human umbilical vein endothelial cells]. | Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20020401 |
| Induction of cytochrome c-mediated apoptosis by amyloid beta 25-35 requires functional mitochondria. | Brain research 20020329 |
| Mutant huntingtin aggregates do not sensitize cells to apoptotic stressors. | FEBS letters 20020327 |
| The non-ankyrin C terminus of Ikappa Balpha physically interacts with p53 in vivo and dissociates in response to apoptotic stress, hypoxia, DNA damage, and transforming growth factor-beta 1-mediated growth suppression. | The Journal of biological chemistry 20020322 |
| The human ovarian surface epithelium is an androgen responsive tissue. | British journal of cancer 20020318 |
| Analysis of the cytochrome c-dependent apoptosis apparatus in cells from human pancreatic carcinoma. | British journal of cancer 20020318 |
| Bcl-X(L) and calyculin A prevent translocation of Bax to mitochondria during apoptosis. | Biochemical and biophysical research communications 20020315 |
| Inactivation of I(A) channels of frog skeletal muscle is modulated by ATP. | Biochemical and biophysical research communications 20020315 |
| Caspase-9 and Apaf-1 are expressed and functionally active in human neuroblastoma tumor cell lines with 1p36 LOH and amplified MYCN. | Oncogene 20020314 |
| Decreased apoptotic response of inclusion-cell disease fibroblasts: a consequence of lysosomal enzyme missorting? | Experimental cell research 20020310 |
| A cellular mechanism that reversibly inactivates pancaspase inhibitor zAsp-CH(2)-DCB: a potential pitfall causing discrepancy between in vitro and in vivo caspase assays. | Biochemical and biophysical research communications 20020308 |
| Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine). | Oncogene 20020307 |
| Effect of calmodulin antagonists on phospholipase D activity in SH-SY5Y cells. | Neurochemistry international 20020301 |
| Interferon-gamma-induced epithelial ICAM-1 expression and monocyte adhesion. Involvement of protein kinase C-dependent c-Src tyrosine kinase activation pathway. | The Journal of biological chemistry 20020301 |
| Caspase-dependent cleavage of carbamoyl phosphate synthetase II during apoptosis. | Molecular pharmacology 20020301 |
| Value of two mortality assessment techniques for organ cultured corneal endothelium: trypan blue versus TUNEL technique. | The British journal of ophthalmology 20020301 |
| Ketamine suppresses norepinephrine-induced inositol 1,4,5-trisphosphate formation via pathways involving protein kinase C. | Anesthesia and analgesia 20020301 |
| The Wnt antagonist Dickkopf-1 is regulated by Bmp signaling and c-Jun and modulates programmed cell death. | The EMBO journal 20020301 |
| Fusion genetic analysis of jasmonate-signalling mutants in Arabidopsis. | The Plant journal : for cell and molecular biology 20020301 |
| Cell cycle-dependent regulation of telomerase activity by auxin, abscisic acid and protein phosphorylation in tobacco BY-2 suspension culture cells. | The Plant journal : for cell and molecular biology 20020301 |
| Retinoic acid increases proliferation rate of GL-15 glioma cells, involving activation of STAT-3 transcription factor. | Journal of neuroscience research 20020301 |
| Radiation-induced phosphorylation of Chk1 at S345 is associated with p53-dependent cell cycle arrest pathways. | Neoplasia (New York, N.Y.) 20020301 |
| Gas1 is induced during and participates in excitotoxic neuronal death. | Molecular and cellular neurosciences 20020301 |
| PKC-alpha shows variable patterns of translocation in response to different stimulatory agents. | Acta physiologica Scandinavica 20020301 |
| Further new staurosporine derivatives from the ascidian Eudistoma toealensis and its predatory flatworm Pseudoceros sp. | Journal of natural products 20020301 |
| Two-color, fluorescence-based microplate assay for apoptosis detection. | BioTechniques 20020301 |
| Procoagulant activity of T lymphoblastoid cells due to exposure of negatively charged phospholipid. | Thrombosis and haemostasis 20020301 |
| Activation of the promoters of Arabidopsis genes for the branched-chain alpha-keto acid dehydrogenase complex in transgenic tobacco BY-2 cells under sugar starvation. | Plant & cell physiology 20020301 |
| New indolocarbazoles as antitumour active compounds: evaluation of the target by experimental and theoretical studies. | Die Pharmazie 20020301 |
| Activation of caspase-3 alone is insufficient for apoptotic morphological changes in human neuroblastoma cells. | Journal of neurochemistry 20020301 |
| Biochemical and molecular effects of UCN-01 in combination with 5-fluorodeoxyuridine in A431 human epidermoid cancer cells. | Anti-cancer drugs 20020301 |
| Light signalling mediated by phytochrome plays an important role in cold-induced gene expression through the C-repeat/dehydration responsive element (C/DRE) in Arabidopsis thaliana. | The Plant journal : for cell and molecular biology 20020301 |
| The role of dopamine and serotonin in regulating bone mass and strength: studies on dopamine and serotonin transporter null mice. | Journal of musculoskeletal & neuronal interactions 20020301 |
| Inhibition of the calcium release-activated calcium (CRAC) current in Jurkat T cells by the HIV-1 envelope protein gp160. | The Journal of biological chemistry 20020222 |
| Effects of inhibitors of the lipo-oxygenase family of enzymes on the store-operated calcium current I(CRAC) in rat basophilic leukaemia cells. | The Journal of physiology 20020215 |
| Inhibition of tumour cell growth by hyperforin, a novel anticancer drug from St. John's wort that acts by induction of apoptosis. | Oncogene 20020214 |
| Modulation of intrinsic P-glycoprotein expression in multicellular prostate tumor spheroids by cell cycle inhibitors. | Biochimica et biophysica acta 20020213 |
| Inhibition of protein phosphatase-1 is linked to phosphorylation of p53 and apoptosis. | Apoptosis : an international journal on programmed cell death 20020201 |
| Annexin V expression in apoptotic peripheral blood lymphocytes: an electron microscopic evaluation. | Apoptosis : an international journal on programmed cell death 20020201 |
| The human homologue of the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis. | The Biochemical journal 20020201 |
| Stimulatory effects of bilirubin on amylase release from isolated rat pancreatic acini. | American journal of physiology. Gastrointestinal and liver physiology 20020201 |
| Depressant effect of ambroxol on stimulated functional responses and cell death in rat alveolar macrophages exposed to silica in vitro. | The Journal of pharmacology and experimental therapeutics 20020201 |
| Down-regulation of Mcl-1 by inhibition of the PI3-K/Akt pathway is required for cell shrinkage-dependent cell death. | Biochemical and biophysical research communications 20020201 |
| Gonadotrophins inhibit the expression of insulin-like growth factor binding protein-related protein-2 mRNA in cultured human granulosa-luteal cells. | Molecular human reproduction 20020201 |
| An MCL1-overexpressing Burkitt lymphoma subline exhibits enhanced survival on exposure to serum deprivation, topoisomerase inhibitors, or staurosporine but remains sensitive to 1-beta-D-arabinofuranosylcytosine. | Cancer research 20020201 |
| Nucleotide-evoked relaxation of rat vas deferens: possible mechanisms. | European journal of pharmacology 20020201 |
| Mechanism of prostaglandin E2-stimulated heat shock protein 27 induction in osteoblast-like MC3T3-E1 cells. | The Journal of endocrinology 20020201 |
| Actions of the selective protein kinase C inhibitor PKC412 on B-chronic lymphocytic leukemia cells in vitro. | Haematologica 20020201 |
| Antileukemia activity of perillyl alcohol (POH): uncoupling apoptosis from G0/G1 arrest suggests that the primary effect of POH on Bcr/Abl-transformed cells is to induce growth arrest. | Leukemia 20020201 |
| Signal transduction of beta2m-induced expression of VCAM-1 and COX-2 in synovial fibroblasts. | Kidney international 20020201 |
| C5a delays apoptosis of human neutrophils by a phosphatidylinositol 3-kinase-signaling pathway. | Kidney international 20020201 |
| Rapid activation of poly(ADP-ribose) polymerase contributes to Sindbis virus and staurosporine-induced apoptotic cell death. | Virology 20020201 |
| Modulation of apoptosis by mitochondrial uncouplers: apoptosis-delaying features despite intrinsic cytotoxicity. | Biochemical pharmacology 20020201 |
| Involvement of protein kinase C and Na+/K+-ATPase in the contractile response induced by myricetin in rat isolated aorta. | Planta medica 20020201 |
| Involvement of caspases and calpains in cerebrocortical neuronal cell death is stimulus-dependent. | British journal of pharmacology 20020201 |
| Carcinogen-induced S-phase arrest is Chk1 mediated and caffeine sensitive. | Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 20020201 |
| Inhibition of heat-induced phosphorylation of stathmin by the bioflavonoid quercetin. | Electrophoresis 20020201 |
| 4,4'-diisothiocyano-2 ,2'-stilbenedisulfonate protects cultured cerebellar granule neurons from death. | Life sciences 20020201 |
| Rescue of trophoblast apoptosis by parathyroid hormone-related protein. | BJOG : an international journal of obstetrics and gynaecology 20020201 |
| A novel conditional Akt 'survival switch' reversibly protects cells from apoptosis. | Gene therapy 20020201 |
| The expression of COX-2 in VEGF-treated endothelial cells is mediated through protein tyrosine kinase. | Mediators of inflammation 20020201 |
| Respiration and mitochondrial membrane potential are not required for apoptosis and anti-apoptotic action of Bcl-2 in HeLa cells. | Biochemistry. Biokhimiia 20020201 |
| A synaptic potentiation by a protein factor distinct from those induced by neurotrophins. | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20020201 |
| Neuronal apoptosis is accompanied by amyloid beta-protein accumulation in the endoplasmic reticulum. | Journal of Alzheimer's disease : JAD 20020201 |
| [Correlation of protein kinase C activity and its subcellular distrubution with multidrug resistance in KVB200 cells]. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20020201 |
| UCN-01 (7-hydroxystaurosporine) inhibits DNA repair and increases cytotoxicity in normal lymphocytes and chronic lymphocytic leukemia lymphocytes. | Molecular cancer therapeutics 20020201 |
| [Protective effects of tacrine and donepezil against staurosporine-induced apoptotic death]. | Yao xue xue bao = Acta pharmaceutica Sinica 20020201 |
| Sendai virus C protein impairs both phosphorylation and dephosphorylation processes of Stat1. | FEBS letters 20020130 |
| Effects of signaling molecules, protein phosphatase inhibitors and blast pathogen (Magnaporthe grisea) on the mRNA level of a rice (Oryza sativa L.) phospholipid hydroperoxide glutathione peroxidase (OsPHGPX) gene in seedling leaves. | Gene 20020123 |
| Aldisine alkaloids from the Philippine sponge Stylissa massa are potent inhibitors of mitogen-activated protein kinase kinase-1 (MEK-1). | Journal of medicinal chemistry 20020117 |
| Inhibition of voltage-gated Ca(2+) current by PACAP in rat adrenal chromaffin cells. | Regulatory peptides 20020115 |
| Resistance of leukemic cells to 2-chlorodeoxyadenosine is due to a lack of calcium-dependent cytochrome c release. | Blood 20020115 |
| Treatment of COS-7 cells with proteasome inhibitors or gamma-interferon reduces the increase in caspase 3 activity associated with staurosporine-induced apoptosis. | Archives of biochemistry and biophysics 20020115 |
| Depletion of intracellular calcium stores is toxic to SH-SY5Y neuronal cells. | Brain research 20020111 |
| Effect of protein kinase C on endoplasmic reticulum cholesterol. | Biochemical and biophysical research communications 20020111 |
| PTEN sensitizes prostate cancer cells to death receptor-mediated and drug-induced apoptosis through a FADD-dependent pathway. | Oncogene 20020110 |
| Mitochondrial dysfunction is an essential step for killing of non-small cell lung carcinomas resistant to conventional treatment. | Oncogene 20020103 |
| Protein kinase C inhibitors. | Current oncology reports 20020101 |
| P-gp-induced modulation of regulatory volume increase occurs via PKC in mouse proximal tubule. | American journal of physiology. Renal physiology 20020101 |
| Cell type-specific and tyrosine phosphorylation-independent nuclear presence of STAT1 and STAT3. | Experimental cell research 20020101 |
| NGF rescues human B lymphocytes from anti-IgM induced apoptosis by activation of PKCzeta. | European journal of immunology 20020101 |
| The prevention of the staurosporine-induced apoptosis by Bcl-X(L), but not by Bcl-2 or caspase inhibitors, allows the extensive differentiation of human neuroblastoma cells. | Journal of neurochemistry 20020101 |
| On the evolution of programmed cell death: apoptosis of the unicellular eukaryote Leishmania major involves cysteine proteinase activation and mitochondrion permeabilization. | Cell death and differentiation 20020101 |
| Pre-processed caspase-9 contained in mitochondria participates in apoptosis. | Cell death and differentiation 20020101 |
| Characterization of the cysteine-rich secretory protein 3 gene as an early-transcribed gene with a putative role in the pathophysiology of Sjögren's syndrome. | Arthritis and rheumatism 20020101 |
| Expression of CTLA-4 by human monocytes. | Scandinavian journal of immunology 20020101 |
| Targeting protein kinase C: new therapeutic opportunities against high-grade malignant gliomas? | The oncologist 20020101 |
| Lysophosphatidic acid augments fibroblast-mediated contraction of released collagen gels. | The Journal of laboratory and clinical medicine 20020101 |
| Effects of finasteride on apoptosis and regulation of the human hair cycle. | Journal of cutaneous medicine and surgery 20020101 |
| Chemiluminescent detection of induced reactive oxygen metabolite production of human polymorphonuclear leucocytes by anthophyllite asbestos. | Environmental research 20020101 |
| Cytotoxic cyplasin of the sea hare, Aaplysia punctata, cDNA cloning, and expression of bioactive recombinants in insect cells. | Neoplasia (New York, N.Y.) 20020101 |
| Lens epithelial cell apoptosis and intracellular Ca2+ increase in the presence of xanthurenic acid. | BMC ophthalmology 20020101 |
| Transforming growth factor-beta1 blocks the enhancement of tumor necrosis factor cytotoxicity by hyaluronidase Hyal-2 in L929 fibroblasts. | BMC cell biology 20020101 |
| Kinetics of apoptotic markers in exogeneously induced apoptosis of EL4 cells. | Journal of cellular and molecular medicine 20020101 |
| Apoptosis-inducing factor (AIF): a novel caspase-independent death effector released from mitochondria. | Biochimie 20020101 |
| Mitochondrial disappearance from cells: a clue to the role of autophagy in programmed cell death and disease? | Biochimie 20020101 |
| Cellular mechanism underlying LPS-induced inhibition of in vitro L-leucine transport across rabbit jejunum. | Journal of endotoxin research 20020101 |
| 5-HT2A receptor activation leads to increased BDNF mRNA expression in C6 glioma cells. | Neuromolecular medicine 20020101 |
| Discordance between the effect of modulators of calcium on staurosporine-induced apoptosis and staurosporine-induced actin degradation. | Cell biology international 20020101 |
| Fragmentation of Golgi complex and Golgi autoantigens during apoptosis and necrosis. | Arthritis research 20020101 |
| A novel treatment approach for low grade lymphoproliferative disorders using PKC412 (CGP41251), an inhibitor of protein kinase C. | The hematology journal : the official journal of the European Haematology Association 20020101 |
| Influence of G2 arrest on the cytotoxicity of DNA topoisomerase inhibitors toward human carcinoma cells with different p53 status. | Acta biochimica Polonica 20020101 |
| Cooperativity between extracellular adenosine 5'-triphosphate and activation of N-methyl-D-aspartate receptors in long-term potentiation induction in hippocampal CA1 neurons. | Neuroscience 20020101 |
| The cell cycle as a target for cancer therapy: basic and clinical findings with the small molecule inhibitors flavopiridol and UCN-01. | The oncologist 20020101 |
| Increased apoptosis in metastatic human colonic adenocarcinomas. | Cancer biology & therapy 20020101 |
| The K252a derivatives, inhibitors for the PAK/MLK kinase family selectively block the growth of RAS transformants. | Cancer journal (Sudbury, Mass.) 20020101 |
| Structural studies with inhibitors of the cell cycle regulatory kinase cyclin-dependent protein kinase 2. | Pharmacology & therapeutics 20020101 |
| Inhibition of protein kinase B/Akt. implications for cancer therapy. | Pharmacology & therapeutics 20020101 |
| UCN-01 (7-hydroxystaurosporine) inhibits the growth of human breast cancer xenografts through disruption of signal transduction. | Breast cancer (Tokyo, Japan) 20020101 |
| Mutant Rab24 GTPase is targeted to nuclear inclusions. | BMC cell biology 20020101 |
| Interleukin-4 induces apoptosis in cultured human follicular keratinocytes, but not in dermal papilla cells. | European journal of dermatology : EJD 20020101 |
| Co-activation of the phosphatidylinositol-3-kinase/Akt signaling pathway by N-methyl-D-aspartate and TrkB receptors in cerebellar granule cell neurons. | Amino acids 20020101 |
| Lactosylceramide-induced apoptosis in primary amnion cells and amnion-derived WISH cells. | Journal of the Society for Gynecologic Investigation 20020101 |
| Role of endogenous regucalcin in nuclear regulation of regenerating rat liver: suppression of the enhanced ribonucleic acid synthesis activity. | Journal of cellular biochemistry 20020101 |
| Nicotinic receptors mediate increased GABA release in brain through a tetrodotoxin-insensitive mechanism during prolonged exposure to nicotine. | Neuroscience 20020101 |
| Selective protection by phosphatidic acid against staurosporine-induced neuronal apoptosis. | Journal of cellular and molecular medicine 20020101 |
| Combining phorbol ester (PMA) with UCN-01: fueling fire with water. | Cell cycle (Georgetown, Tex.) 20020101 |
| UCN-01 (7-hydroxystauorsporine) blocks PMA-induced maturation and reciprocally promotes apoptosis in human myelomonocytic leukemia cells (U937). | Cell cycle (Georgetown, Tex.) 20020101 |
| Inhibitors of MEK1/2 interact with UCN-01 to induce apoptosis and reduce colony formation in mammary and prostate carcinoma cells. | Cancer biology & therapy 20020101 |
| CHK and MEK inhibitors team up to trigger cancer cell suicide. | Cancer biology & therapy 20020101 |
| Effects of polyphenolic anthrone derivatives, resistomycin and hypercin, on apoptosis in human megakaryoblastic leukemia CMK-7 cell line. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101 |
| [Influence of protein kinase C on motility and acrosome reaction of sperm]. | Zhonghua nan ke xue = National journal of andrology 20020101 |
| Mitochondrial defects in cancer. | Molecular cancer 20020101 |
| Independent antitumor spectrum of UCN-01 (7-hydroxystaurosporine) against gastric and colorectal cancers as detected by MTT assay. | Anticancer research 20020101 |
| [Effects of praeruptorin C on cell hypertrophy, intracellular [Ca2+]i, nitric oxide and signal transduction in isolated hypertrophied rat smooth muscle cells induced by angiotensin II]. | Yao xue xue bao = Acta pharmaceutica Sinica 20020101 |
| Stimulus-dependent activation of NF-kappaB specifies apoptosis or neuroprotection in cerebellar granule cells. | Neuromolecular medicine 20020101 |
| Coadministration of UCN-01 with MEK1/2 inhibitors potently induces apoptosis in BCR/ABL+ leukemia cells sensitive and resistant to ST1571. | Cancer biology & therapy 20020101 |
| Beyond directed therapeutics--are two drugs always better than one? | Cancer biology & therapy 20020101 |
| Mapping of the interaction sites between apoptosis linked gene ALG-2 and HEED. | Molecules and cells 20011231 |
| Anti-proliferative effects of new staurosporine derivatives isolated from a marine ascidian and its predatory flatworm. | Cancer letters 20011228 |
| Agonist-dependent dissociation of oligomeric complexes of G protein-coupled cholecystokinin receptors demonstrated in living cells using bioluminescence resonance energy transfer. | The Journal of biological chemistry 20011221 |
| Electrophoretic characterization of ribosomal subunits and proteins in apoptosis: specific downregulation of S11 in staurosporine-treated human breast carcinoma cells. | Biochemistry 20011218 |
| The exocytotic signaling pathway induced by nerve growth factor in the presence of lyso-phosphatidylserine in rat peritoneal mast cells involves a type D phospholipase. | Regulatory peptides 20011215 |
| A study of mechanisms underlying amitriptyline-induced acute lung function impairment. | Toxicology and applied pharmacology 20011215 |
| Staurosporine treatment and serum starvation promote the cleavage of emerin in cultured mouse myoblasts: involvement of a caspase-dependent mechanism. | FEBS letters 20011214 |
| Nuclear translocation of PDCD5 (TFAR19): an early signal for apoptosis? | FEBS letters 20011207 |
| Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2. | The EMBO journal 20011203 |
| Mechanisms of modulation of neuronal nicotinic receptors by substance P and OAG. | American journal of physiology. Cell physiology 20011201 |
| Lymnaea epidermal growth factor promotes axonal regeneration in CNS organ culture. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20011201 |
| Development and validation of a competitive AKT serine/threonine kinase fluorescence polarization assay using a product-specific anti-phospho-serine antibody. | Analytical biochemistry 20011201 |
| Regulation of vascular proteoglycan synthesis by angiotensin II type 1 and type 2 receptors. | Journal of the American Society of Nephrology : JASN 20011201 |
| Human cervical cancer cells use Ca2+ signalling, protein tyrosine phosphorylation and MAP kinase in regulatory volume decrease. | The Journal of physiology 20011201 |
| Accelerating the induction of Fas-mediated T cell apoptosis: a strategy for transplant tolerance? | Clinical and experimental immunology 20011201 |
| Cellular overexpression of heme oxygenase-1 up-regulates p21 and confers resistance to apoptosis. | Kidney international 20011201 |
| Apoptosis in sea urchin oocytes, eggs, and early embryos. | Molecular reproduction and development 20011201 |
| Effects of calcium, calmodulin, protein kinase C and protein tyrosine kinases on volume-activated taurine efflux in human erythroleukemia cells. | Journal of cellular physiology 20011201 |
| Pro-apoptotic effect of presenilin 2 (PS2) overexpression is associated with down-regulation of Bcl-2 in cultured neurons. | Journal of neurochemistry 20011201 |
| Modulation of microglial superoxide production by alpha-tocopherol in vitro: attenuation of p67(phox) translocation by a protein phosphatase-dependent pathway. | Journal of neurochemistry 20011201 |
| Programmed cell death in mature erythrocytes: a model for investigating death effector pathways operating in the absence of mitochondria. | Cell death and differentiation 20011201 |
| Caspase-dependent deubiquitination of monoubiquitinated nucleosomal histone H2A induced by diverse apoptogenic stimuli. | Cell death and differentiation 20011201 |
| L-NAME-induced dispersion of melanosomes in melanophores activates PKC, MEK and ERK1. | Pigment cell research 20011201 |
| A common molecular machinery for exocytosis and the 'kiss-and-run' mechanism in chromaffin cells is controlled by phosphorylation. | Journal of cell science 20011201 |
| Redox-regulation of the expression of the peroxide-detoxifying chloroplast 2-cys peroxiredoxin in the liverwort Riccia fluitans. | Planta 20011201 |
| Alpha-tocopherol modulates tyrosine phosphorylation in human neutrophils by inhibition of protein kinase C activity and activation of tyrosine phosphatases. | Free radical research 20011201 |
| Inhibitory effect of menaquinone-7 (vitamin K2) on osteoclast-like cell formation and osteoclastic bone resorption in rat bone tissues in vitro. | Molecular and cellular biochemistry 20011201 |
| Divers pathways mediate delta-opioid receptor down regulation within the same cell. | Brain research. Molecular brain research 20011130 |
| Regulation of epithelial sodium channel activity through a region of the carboxyl terminus of the alpha -subunit. Evidence for intracellular kinase-mediated reactions. | The Journal of biological chemistry 20011123 |
| Human bcl-2 gene attenuates the ability of rabbit lens epithelial cells against H2O2-induced apoptosis through down-regulation of the alpha B-crystallin gene. | The Journal of biological chemistry 20011116 |
| The phosphatidylinositide 3'-kinase/Akt survival pathway is a target for the anticancer and radiosensitizing agent PKC412, an inhibitor of protein kinase C. | Cancer research 20011115 |
| Protein kinase inhibitors and the dynamics of tight junction opening and closing in A6 cell monolayers. | The Journal of membrane biology 20011115 |
| Ceramide modulates nicotinic receptor-dependent Ca(2+) signaling in rat chromaffin cells. | Journal of neuroscience research 20011115 |
| Cyclic AMP differentiation of the oligodendroglial cell line N20.1 switches staurosporine-induced cell death from necrosis to apoptosis. | Journal of neuroscience research 20011115 |
| Stabilization of cortical actin induces internalization of transient receptor potential 3 (Trp3)-associated caveolar Ca2+ signaling complex and loss of Ca2+ influx without disruption of Trp3-inositol trisphosphate receptor association. | The Journal of biological chemistry 20011109 |
| Inhibition of voltage-gated K(+) currents by endothelin-1 in human pulmonary arterial myocytes. | American journal of physiology. Lung cellular and molecular physiology 20011101 |
| Endothelin-1 decreases glutamate uptake in primary cultured rat astrocytes. | American journal of physiology. Cell physiology 20011101 |
| cDNA microarray analysis of multidrug resistance: doxorubicin selection produces multiple defects in apoptosis signaling pathways. | The Journal of pharmacology and experimental therapeutics 20011101 |
| Differences in rapid desensitization of 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptor-mediated phospholipase C activation. | The Journal of pharmacology and experimental therapeutics 20011101 |
| Trafficking-dependent and -independent pathways of neurotransmitter transporter regulation differentially involving p38 mitogen-activated protein kinase revealed in studies of insulin modulation of norepinephrine transport in SK-N-SH cells. | The Journal of pharmacology and experimental therapeutics 20011101 |
| Multiple kinetics of mitochondrial cytochrome c release in drug-induced apoptosis. | Molecular pharmacology 20011101 |
| Resistance to Fas-mediated apoptosis in EBV-infected B cell lymphomas is due to defects in the proximal Fas signaling pathway. | Journal of immunology (Baltimore, Md. : 1950) 20011101 |
| Attenuated agonist evoked vasoconstrictor responses in the perfused mesenteric vascular bed of streptozotocin diabetic rats. | Experimental biology and medicine (Maywood, N.J.) 20011101 |
| In rat hepatocytes, the hypertonic activation of Na(+) conductance and Na(+)-K(+)-2Cl(-) symport--but not Na(+)-H(+) antiport--is mediated by protein kinase C. | The Journal of physiology 20011101 |
| The tuberous sclerosis 2 gene product can localize to nuclei in a phosphorylation-dependent manner. | Molecular cell biology research communications : MCBRC 20011101 |
| Neurotransmitter action in osteoblasts: expression of a functional system for serotonin receptor activation and reuptake. | Bone 20011101 |
| Secondary necrosis is a source of proteolytically modified forms of specific intracellular autoantigens: implications for systemic autoimmunity. | Arthritis and rheumatism 20011101 |
| Cyclic strain increases protease-activated receptor-1 expression in vascular smooth muscle cells. | Hypertension (Dallas, Tex. : 1979) 20011101 |
| The in-vitro characterization of induced apoptosis in placental cytotrophoblasts and syncytiotrophoblasts. | Placenta 20011101 |
| Rapid dynamics of the microtubule binding of ensconsin in vivo. | Journal of cell science 20011101 |
| Unexpected effects of FERM domain mutations on catalytic activity of Jak3: structural implication for Janus kinases. | Molecular cell 20011101 |
| Transforming growth factor-beta1 enhances expression of brain-derived neurotrophic factor and its receptor, TrkB, in neurons cultured from rat cerebral cortex. | Journal of neuroscience research 20011101 |
| Cytotoxicity induced by manipulation of signal transduction pathways is associated with down-regulation of Bcl-2 but not Mcl-1 in MCF-7 human breast cancer. | Breast cancer research and treatment 20011101 |
| Matrilysin [MMP-7] expression selects for cells with reduced sensitivity to apoptosis. | Neoplasia (New York, N.Y.) 20011101 |
| The POU domain transcription factor Brn-3a protects cortical neurons from apoptosis. | Neuroreport 20011029 |
| The effect of leptin on Na(+)-H(+) antiport (NHE 1) activity of obese and normal subjects erythrocytes. | Molecular and cellular endocrinology 20011025 |
| Synthesis and biological evaluation of novel bisindolylmaleimides that inhibit vascular endothelial cell proliferation. | Bioorganic & medicinal chemistry letters 20011022 |
| Negative regulation of IL-1beta production at the level of transcription in macrophages stimulated with LPS. | Cytokine 20011021 |
| Caspase-mediated cleavage of the Ca2+/calmodulin-dependent protein kinase-like kinase facilitates neuronal apoptosis. | The Journal of biological chemistry 20011019 |
| Unreliability of the cytochrome c-enhanced green fluorescent fusion protein as a marker of cytochrome c release in cells that overexpress Bcl-2. | The Journal of biological chemistry 20011019 |
| Neurotrophin p75 receptor is involved in neuronal damage by prion peptide-(106-126). | The Journal of biological chemistry 20011019 |
| PTEN induces chemosensitivity in PTEN-mutated prostate cancer cells by suppression of Bcl-2 expression. | The Journal of biological chemistry 20011019 |
| Antagonizing effect of protein kinase C activation on the mu-opioid agonist-induced inhibition of high voltage-activated calcium current in rat periaqueductal gray neuron. | Brain research 20011019 |
| Contribution of apoptosis to responses in the comet assay. | Mutation research 20011018 |
| Human Scythe contains a functional nuclear localization sequence and remains in the nucleus during staurosporine-induced apoptosis. | Biochemical and biophysical research communications 20011012 |
| Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3 beta. | The Journal of biological chemistry 20011005 |
| The role of ceramide in receptor- and stress-induced apoptosis studied in acidic ceramidase-deficient Farber disease cells. | Oncogene 20011004 |
| K-Cl cotransport modulation by intracellular Mg in erythrocytes from mice bred for low and high Mg levels. | American journal of physiology. Cell physiology 20011001 |
| Role of protein kinase C in myogenic calcium-contraction coupling of rat cannulated mesenteric small arteries. | Clinical and experimental pharmacology & physiology 20011001 |
| Phosphorylation-dependent modulation of cardiac calcium current by intracellular free magnesium. | American journal of physiology. Heart and circulatory physiology 20011001 |
| Important role of energy-dependent mitochondrial pathways in cultured rat cardiac myocyte apoptosis. | American journal of physiology. Heart and circulatory physiology 20011001 |
| Augmented K(+) currents and mitochondrial membrane depolarization in pulmonary artery myocyte apoptosis. | American journal of physiology. Lung cellular and molecular physiology 20011001 |
| Pulmonary artery vasoconstriction but not [Ca2+]i signal stimulated by thromboxane A2 is partially resistant to NO. | Pediatric research 20011001 |
| Detection of the presenilin 1 COOH-terminal fragment in the extracellular compartment: a release enhanced by apoptosis. | Experimental cell research 20011001 |
| Measurement of apoptosis in long-term cultures of human ovarian tissue. | Reproduction (Cambridge, England) 20011001 |
| Okadaic acid-sensitive activation of Maxi Cl(-) channels by triphenylethylene antioestrogens in C1300 mouse neuroblastoma cells. | The Journal of physiology 20011001 |
| A flow cytometry assay simultaneously detects independent apoptotic parameters. | Cytometry 20011001 |
| Attenuation of Zn2+ neurotoxicity by aspirin: role of N-type Ca2+ channel and the carboxyl acid group. | Neurobiology of disease 20011001 |
| In vitro prevention of the emergence of multidrug resistance in a pediatric rhabdomyosarcoma cell line. | Clinical cancer research : an official journal of the American Association for Cancer Research 20011001 |
| The mechanism of mitochondrial membrane potential retention following release of cytochrome c in apoptotic GT1-7 neural cells. | Cell death and differentiation 20011001 |
| Chelerythrine rapidly induces apoptosis through generation of reactive oxygen species in cardiac myocytes. | Journal of molecular and cellular cardiology 20011001 |
| Electrical stimulation of cerebellar fastigial nucleus protects rat brain, in vitro, from staurosporine-induced apoptosis. | Journal of neurochemistry 20011001 |
| Effect of Leishmania donovani lipophosphoglycan on ornithine decarboxylase activity in macrophages. | The Journal of parasitology 20011001 |
| Acidosis inhibits gallbladder contraction mediated by protein kinase C activation. | Japanese journal of pharmacology 20011001 |
| Brain-derived neurotrophic factor induces long-lasting potentiation of synaptic transmission in visual cortex in vivo in young rats, but not in the adult. | The European journal of neuroscience 20011001 |
| Sequential degradation of proteins from the nuclear envelope during apoptosis. | Journal of cell science 20011001 |
| Secretion of gelatinases and activation of gelatinase A (MMP-2) by human rheumatoid synovial fibroblasts. | Biological chemistry 20011001 |
| K-Cl co-transport: immunocytochemical and functional evidence for more than one KCC isoform in high K and low K sheep erythrocytes. | Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20011001 |
| Evidence that increased tyrosine phosphorylation causes disassembly of adherens junctions but does not perturb paracellular permeability in Caco-2 cells. | Tissue & cell 20011001 |
| Hormone-mediated dephosphorylation of specific histone H1 isoforms. | The Journal of biological chemistry 20010928 |
| In vitro studies show that Hsp70 can be released by glia and that exogenous Hsp70 can enhance neuronal stress tolerance. | Brain research 20010928 |
| Phosphorylation of native and heme-modified CYP3A4 by protein kinase C: a mass spectrometric characterization of the phosphorylated peptides. | Biochemistry 20010925 |
| c-myc box II mutations in Burkitt's lymphoma-derived alleles reduce cell-transformation activity and lower response to broad apoptotic stimuli. | Oncogene 20010920 |
| A diacylglycerol-activated Ca2+ channel in PC12 cells (an adrenal chromaffin cell line) correlates with expression of the TRP-6 (transient receptor potential) protein. | The Biochemical journal 20010915 |
| Inhibition of extracellular Ca(2+) entry by YC-1, an activator of soluble guanylyl cyclase, through a cyclic GMP-independent pathway in rat neutrophils. | Biochemical pharmacology 20010915 |
| The P2Y(12) receptor induces platelet aggregation through weak activation of the alpha(IIb)beta(3) integrin--a phosphoinositide 3-kinase-dependent mechanism. | FEBS letters 20010914 |
| Caspase-dependent cleavage of ErbB-2 by geldanamycin and staurosporin. | The Journal of biological chemistry 20010907 |
| A role for mitochondrial Bak in apoptotic response to anticancer drugs. | The Journal of biological chemistry 20010907 |
| Estrogen effects in the myocardium: inhibition of NF-kappaB DNA binding by estrogen receptor-alpha and -beta. | Biochemical and biophysical research communications 20010907 |
| Activation of the MKK4-JNK pathway during erythroid differentiation of K562 cells is inhibited by the heat shock factor 2-beta isoform. | FEBS letters 20010907 |
| Development of a simplified, sensitive high-performance liquid chromatographic method using fluorescence detection to determine the concentration of UCN-01 in human plasma. | Journal of chromatography. B, Biomedical sciences and applications 20010905 |
| Role of Ca2+-sensitive protein kinase C in phenylephrine enhancement of Ca2+ sensitivity in rat tail artery. | Journal of cardiovascular pharmacology 20010901 |
| Phosphate-induced chondrocyte apoptosis is linked to nitric oxide generation. | American journal of physiology. Cell physiology 20010901 |
| Differential sensitivity of mesencephalic neurons to inhibition of phosphatase 2A. | The Journal of pharmacology and experimental therapeutics 20010901 |
| Protein kinase C, rather than protein kinase A is involved in follicle-stimulating hormone-mediated meiotic resumption of mouse cumulus cell-enclosed oocytes in hypoxanthine-supplemented medium. | Molecular and cellular endocrinology 20010901 |
| Contraction coupled endothelial nitric oxide release: a new paradigm for local vascular control? | The Journal of surgical research 20010901 |
| Attenuation of staurosporine-induced apoptosis, oxidative stress, and mitochondrial dysfunction by synthetic superoxide dismutase and catalase mimetics, in cultured cortical neurons. | Experimental neurology 20010901 |
| Rapid extracellular release of cytochrome c is specific for apoptosis and marks cell death in vivo. | Blood 20010901 |
| Bax translocation to mitochondria subsequent to a rapid loss of mitochondrial membrane potential. | Cell death and differentiation 20010901 |
| Thymocytes selected for resistance to hydrogen peroxide show altered antioxidant enzyme profiles and resistance to dexamethasone-induced apoptosis. | Cell death and differentiation 20010901 |
| Permeability of human HT-29/B6 colonic epithelium as a function of apoptosis. | The Journal of physiology 20010901 |
| Role of calcineurin in insulin-like growth factor-1-induced hypertrophy of cultured adult rat ventricular myocytes. | Japanese circulation journal 20010901 |
| Detection of caspase activation in situ by fluorochrome-labeled caspase inhibitors. | BioTechniques 20010901 |
| Identification of hTAF(II)80 delta links apoptotic signaling pathways to transcription factor TFIID function. | Molecular cell 20010901 |
| [The mechanism of enhanced platelet intracellular calcium mobilization stimulated by serotonin--in the pathophysiology of mood disorders]. | [Hokkaido igaku zasshi] The Hokkaido journal of medical science 20010901 |
| Simulation of ischemic reperfusion in endothelial cell culture increases apoptosis. | The journal of extra-corporeal technology 20010901 |
| Stimulatory effect of zinc on deoxyribonucleic acid synthesis in bone growth of newborn rats: enhancement with zinc and insulin-like growth factor-I. | Calcified tissue international 20010901 |
| Blocking Chk1 expression induces apoptosis and abrogates the G2 checkpoint mechanism. | Neoplasia (New York, N.Y.) 20010901 |
| Propranolol increases phosphatidic acid level via activation of phospholipase D. | Acta pharmacologica Sinica 20010901 |
| Visualizing postendocytic traffic of synaptic vesicles at hippocampal synapses. | Neuron 20010830 |
| BDNF induces glutamate release in cerebrocortical nerve terminals and in cortical astrocytes. | Neuroreport 20010828 |
| TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer. | The Journal of biological chemistry 20010824 |
| Differences in functional consequences and signal transduction induced by IL-3, IL-5, and nerve growth factor in human basophils. | Journal of immunology (Baltimore, Md. : 1950) 20010815 |
| The adapter protein apoptotic protease-activating factor-1 (Apaf-1) is proteolytically processed during apoptosis. | The Journal of biological chemistry 20010810 |
| Akt is activated in response to an apoptotic signal. | The Journal of biological chemistry 20010810 |
| A concise synthesis of rac-staurosporine glycon. | The Journal of organic chemistry 20010810 |
| The protonophore CCCP induces mitochondrial permeability transition without cytochrome c release in human osteosarcoma cells. | FEBS letters 20010810 |
| K252a, an indrocarbazole derivative, causes the membrane of myoblasts to enter a fusion-capable state. | Biochemical and biophysical research communications 20010803 |
| Cigarette smoke extract induces endothelin-1 via protein kinase C in pulmonary artery endothelial cells. | American journal of physiology. Lung cellular and molecular physiology 20010801 |
| A role for MAP kinase in regulating ectodomain shedding of APLP2 in corneal epithelial cells. | American journal of physiology. Cell physiology 20010801 |
| Vitamin C transport in human lens epithelial cells: evidence for the presence of SVCT2. | Experimental eye research 20010801 |
| Measurement of proteases using chemiluminescence-resonance-energy-transfer chimaeras between green fluorescent protein and aequorin. | The Biochemical journal 20010801 |
| Ascorbic acid enhances arsenic trioxide-induced cytotoxicity in multiple myeloma cells. | Blood 20010801 |
| Lipoprotein-X stimulates monocyte chemoattractant protein-1 expression in mesangial cells via nuclear factor-kappa B. | Kidney international 20010801 |
| Abrogation of the Chk1-mediated G(2) checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells. | Cancer research 20010801 |
| Mechanism of prostaglandin D(2)-stimulated heat shock protein 27 induction in osteoblasts. | Cellular signalling 20010801 |
| Tumor necrosis factor alpha-induced activation of downstream NF-kappaB site of the promoter mediates epithelial ICAM-1 expression and monocyte adhesion. Involvement of PKCalpha, tyrosine kinase, and IKK2, but not MAPKs, pathway. | Cellular signalling 20010801 |
| Uncoupling of ATP-induced inositol phosphate formation and Ca(2+) mobilization by phorbol ester in canine cultured tracheal epithelial cells. | Cellular signalling 20010801 |
| Protein kinase C signalling pathway is involved in the regulation of vascular endothelial growth factor expression in human bladder transitional carcinoma cells. | Cellular signalling 20010801 |
| HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity. | Journal of neurochemistry 20010801 |
| Inorganic lead stimulates DNA synthesis in human astrocytoma cells: role of protein kinase Calpha. | Journal of neurochemistry 20010801 |
| Subcellular redistribution of BAX during apoptosis induced by anticancer drugs. | Anti-cancer drugs 20010801 |
| 5-HT1A receptor-mediated activation of G-protein-gated inwardly rectifying K+ current in rat periaqueductal gray neurons. | Neuropharmacology 20010801 |
| Cleavage of bid may amplify caspase-8-induced neuronal death following focally evoked limbic seizures. | Neurobiology of disease 20010801 |
| Anticancer drug-mediated induction of multidrug resistance-associated genes and protein kinase C isozymes in the T-lymphoblastoid cell line CCRF-CEM and in blasts from patients with acute lymphoblastic leukemias. | Japanese journal of cancer research : Gann 20010801 |
| Preconditioning-induced neuroprotection is mediated by reactive oxygen species and activation of the transcription factor nuclear factor-kappaB. | Journal of neurochemistry 20010801 |
| Susceptibility of thyroid cancer cells to 7-hydroxystaurosporine-induced apoptosis correlates with Bcl-2 protein level. | Thyroid : official journal of the American Thyroid Association 20010801 |
| Transient expression of the Bcl-2 family member, A1-a, results in nuclear localization and resistance to staurosporine-induced apoptosis. | Cell death and differentiation 20010801 |
| Staurosporine inhibits phosphorylation of translational regulators linked to mTOR. | Cell death and differentiation 20010801 |
| Establishment of a tetraploid Meth-A cell line through polyploidization by demecolcine but not by staurosporine, K-252A and paclitaxel. | Cell proliferation 20010801 |
| Induction of tyrosine phosphorylated proteins in THP-1 cells by Salmonella typhimurium, Pasteurella haemolytica and Haemophilus influenzae porins. | FEMS immunology and medical microbiology 20010801 |
| Protein kinase and phosphatase activities are involved in fructan synthesis initiation mediated by sugars. | Planta 20010801 |
| Genistein, a soybean isoflavone, inhibits inward rectifier K(+) channels in rat osteoclasts. | The Japanese journal of physiology 20010801 |
| Retinoic acid causes MEK-dependent RAF phosphorylation through RARalpha plus RXR activation in HL-60 cells. | Differentiation; research in biological diversity 20010801 |
| Pro-apoptotic interactions between XK469 and the peripheral benzodiazepine receptor. | Cancer letters 20010726 |
| 12-O-tetradecanoylphorbol-13-acetate induces Epstein-Barr virus reactivation via NF-kappaB and AP-1 as regulated by protein kinase C and mitogen-activated protein kinase. | Virology 20010720 |
| The generation of superoxide anion in blood platelets in response to different forms of Proteus mirabilis lipopolysaccharide: effects of staurosporin, wortmannin, and indomethacin. | Thrombosis research 20010715 |
| Protein kinase C activates store-operated Ca(2+) channels in human glomerular mesangial cells. | The Journal of biological chemistry 20010713 |
| Insulin-stimulated protein kinase B phosphorylation on Ser-473 is independent of its activity and occurs through a staurosporine-insensitive kinase. | The Journal of biological chemistry 20010713 |
| Involvement of p-15(INK4b) and p-16(INK4a) gene expression in saikosaponin a and TPA-induced growth inhibition of HepG2 cells. | Biochemical and biophysical research communications 20010713 |
| PKCdelta-dependent deubiquitination and stabilization of Gadd45 in A431 cells overexposed to EGF. | Biochemical and biophysical research communications 20010713 |
| Differential responses of human neuroblastoma and glioblastoma to apoptosis. | Brain research. Molecular brain research 20010713 |
| Signal transduction in eclosion hormone-induced secretion of ecdysis-triggering hormone. | The Journal of biological chemistry 20010706 |
| Enzyme-linked immunosorbent assay (ELISA) for the specific detection of apoptotic cells and its application to rapid drug screening. | Journal of immunological methods 20010701 |
| Bcl-2 decreases voltage-gated K+ channel activity and enhances survival in vascular smooth muscle cells. | American journal of physiology. Cell physiology 20010701 |
| Bradykinin augments fibroblast-mediated contraction of released collagen gels. | American journal of physiology. Lung cellular and molecular physiology 20010701 |
| Role of zinc in pulmonary endothelial cell response to oxidative stress. | American journal of physiology. Lung cellular and molecular physiology 20010701 |
| UCN-01 dose-dependent inhibition of normal hyperproliferative cells in mice. | International journal of oncology 20010701 |
| The mechanisms of serum-treated zymosan (STZ)-induced oxidative metabolism by human eosinophils and the effects of IL-5 priming. | Allergy 20010701 |
| Mechanisms of endothelin-1-induced potentiation of noradrenaline response in rat mesenteric artery. | Clinical and experimental pharmacology & physiology 20010701 |
| Glyoxal and methylglyoxal trigger distinct signals for map family kinases and caspase activation in human endothelial cells. | Free radical biology & medicine 20010701 |
| H+-ATPase-mediated cytoplasmic pH-responses associated with elevation of cytoplasmic calcium in cultured rabbit nonpigmented ciliary epithelium. | The Journal of membrane biology 20010701 |
| Dissipation of potassium and proton gradients inhibits mitochondrial hyperpolarization and cytochrome c release during neural apoptosis. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20010701 |
| Pharmacological inhibitors of the mitogen-activated protein kinase (MAPK) kinase/MAPK cascade interact synergistically with UCN-01 to induce mitochondrial dysfunction and apoptosis in human leukemia cells. | Cancer research 20010701 |
| Expression and role of Bcl-xL in human hepatocellular carcinomas. | Hepatology (Baltimore, Md.) 20010701 |
| Role of DNA-dependent protein kinase in neuronal survival. | Journal of neurochemistry 20010701 |
| Rapid stimulatory effects of brain-derived neurotrophic factor and neurotrophin-3 on somatostatin release and intracellular calcium rise in primary hypothalamic cell cultures. | Neuroendocrinology 20010701 |
| Characterization of Itk tyrosine kinase: contribution of noncatalytic domains to enzymatic activity. | Protein expression and purification 20010701 |
| Bcl-2 expression by retrograde transport of adenoviral vectors with Cre-loxP recombination system in motor neurons of mutant SOD1 transgenic mice. | Gene therapy 20010701 |
| Antigonadotropic action of adenosine triphosphate in human granulosa-luteal cells: involvement of protein kinase Calpha. | The Journal of clinical endocrinology and metabolism 20010701 |
| Group II mGlu receptor agonists fail to protect against various neurotoxic insults induced in murine cortical, striatal and cerebellar granular pure neuronal cultures. | Neuropharmacology 20010701 |
| Protein binding alters the activity of suramin, carboxyamidotriazole, and UCN-01 in an ex vivo rat aortic ring angiogenesis assay. | Clinical cancer research : an official journal of the American Association for Cancer Research 20010701 |
| Stimulation of interleukin-6 promoter by parathyroid hormone, tumor necrosis factor alpha, and interleukin-1beta in UMR-106 osteoblastic cells is inhibited by protein kinase C antagonists. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010701 |
| Signal transduction pathways in directed migration of human monocytes induced by human growth hormone in vitro. | International immunopharmacology 20010701 |
| Attenuation of neurotoxicity in cortical cultures and hippocampal slices from E2F1 knockout mice. | Journal of neurochemistry 20010701 |
| The trigger to cell death determines the efficiency with which dying cells are cleared by neighbours. | Cell death and differentiation 20010701 |
| Establishment of okadaic acid resistant cell clones using a cDNA expression library. | Cell death and differentiation 20010701 |
| Expression of protein kinase C isoforms in euxanthone-induced differentiation of neuroblastoma cells. | Planta medica 20010701 |
| Activation of muscarinic receptors induces protein synthesis-dependent long-lasting depression in the perirhinal cortex. | The European journal of neuroscience 20010701 |
| Apoptosis: biphasic dose responses. | Critical reviews in toxicology 20010701 |
| A protective role of PKCepsilon against TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in glioma cells. | Biochemical and biophysical research communications 20010629 |
| The p75 neurotrophin receptor activates Akt (protein kinase B) through a phosphatidylinositol 3-kinase-dependent pathway. | The Journal of biological chemistry 20010622 |
| Thiophosphorylation-induced Ca(2+) sensitization of guinea-pig ileum contractility is not mediated by Rho-associated kinase. | The Journal of physiology 20010615 |
| Peroxynitrite activates mitogen-activated protein kinase (MAPK) via a MEK-independent pathway: a role for protein kinase C. | FEBS letters 20010615 |
| Identification of human endomucin-1 and -2 as membrane-bound O-sialoglycoproteins with anti-adhesive activity. | FEBS letters 20010615 |
| Peroxisomes exist in growth cones and move anterogradely and retrogradely in neurites of PC12D cells. | Experimental cell research 20010610 |
| Staurosporine induces apoptosis through both caspase-dependent and caspase-independent mechanisms. | Oncogene 20010607 |
| Studies about the mechanism of internalization by mammary epithelial cells of Escherichia coli isolated from persistent bovine mastitis. | Veterinary microbiology 20010606 |
| K(+) transport in red blood cells from human umbilical cord. | Biochimica et biophysica acta 20010606 |
| MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activation. | The Journal of biological chemistry 20010601 |
| Calsenilin is a substrate for caspase-3 that preferentially interacts with the familial Alzheimer's disease-associated C-terminal fragment of presenilin 2. | The Journal of biological chemistry 20010601 |
| Calcium-sensing receptor activation induces intracellular calcium oscillations. | American journal of physiology. Cell physiology 20010601 |
| Inhibition of carbachol stimulated acid secretion by interleukin 1beta in rabbit parietal cells requires protein kinase C. | Gut 20010601 |
| Prevention of staurosporine-induced cell death in embryonic chick cardiomyocyte is more dependent on caspase-2 than caspase-3 inhibition and is independent of sphingomyelinase activation and ceramide generation. | Archives of biochemistry and biophysics 20010601 |
| CD44 ligation on peripheral blood polymorphonuclear cells induces interleukin-6 production. | Blood 20010601 |
| mGluR1-mediated potentiation of NMDA receptors involves a rise in intracellular calcium and activation of protein kinase C. | Neuropharmacology 20010601 |
| UCN-01 induces cytotoxicity toward human CLL cells through a p53-independent mechanism. | Experimental hematology 20010601 |
| Induction of plant gp91 phox homolog by fungal cell wall, arachidonic acid, and salicylic acid in potato. | Molecular plant-microbe interactions : MPMI 20010601 |
| Group I mGluRs coupled to G proteins are regulated by tyrosine kinase in dopamine neurons of the rat midbrain. | Journal of neurophysiology 20010601 |
| Caspase-independent cell death and mitochondrial disruptions observed in the Apaf1-deficient cells. | Journal of biochemistry 20010601 |
| Nongenomic antiapoptotic signal transduction by estrogen in cultured cortical neurons. | Journal of neuroscience research 20010601 |
| CGP 41251, a new potential anticancer drug, improves contractility of rat isolated cardiac muscle subjected to hypoxia. | Journal of cardiovascular pharmacology 20010601 |
| Role of protein kinase C and phosphatases in the pulmonary vasculature of neonatal piglets. | Critical care medicine 20010601 |
| Cleavage of Bax is mediated by caspase-dependent or -independent calpain activation in dopaminergic neuronal cells: protective role of Bcl-2. | Journal of neurochemistry 20010601 |
| Activation of store-operated Ca2+ entry in RBL cells without the contribution of protein kinases. | Naunyn-Schmiedeberg's archives of pharmacology 20010601 |
| ATP but not adenosine inhibits nonquantal acetylcholine release at the mouse neuromuscular junction. | The European journal of neuroscience 20010601 |
| Impaired sensitivity to beta 2 integrin-blocking in ICAM-1-mediated neutrophil migration in ulcerative colitis. | Scandinavian journal of gastroenterology 20010601 |
| Synergistic effects of highly unsaturated fatty acid-containing phosphatidyl-ethanolamine on differentiation of human leukemia HL-60 cells by dibutyryl cyclic adenosine monophosphate. | Japanese journal of cancer research : Gann 20010601 |
| Ca2+-dependent and Ca2+-independent excretion modes of salicylic acid in tobacco cell suspension culture. | Journal of experimental botany 20010601 |
| Characterization of alpha 5-integrin-dependent mast cell adhesion following Fc epsilon RI aggregation. | International archives of allergy and immunology 20010601 |
| Growth inhibition and apoptosis induced by P2Y2 receptors in human colorectal carcinoma cells: involvement of intracellular calcium and cyclic adenosine monophosphate. | International journal of colorectal disease 20010601 |
| The biosynthesis of shikimate metabolites. | Natural product reports 20010601 |
| Protein kinase C and phosphatidylinositol 3-kinase independently contribute to P-glycoprotein-mediated drug secretion in the mouse proximal tubule. | Pflugers Archiv : European journal of physiology 20010601 |
| Effects of phosphatidylinositol kinase inhibitors on the activation of the store-operated calcium current ICRAC in RBL-1 cells. | Pflugers Archiv : European journal of physiology 20010601 |
| Necrosis and apoptosis in lymphoma cell lines exposed to eicosapentaenoic acid and antioxidants. | Lipids 20010601 |
| Differential processing of cytosolic and mitochondrial caspases. | Mitochondrion 20010601 |
| Efficient syntheses of novel C2'-alkylated (+/-)-K252a analogues. | Organic letters 20010531 |
| Possible mechanisms regulating ATP- and thimerosal-induced Ca(2+) oscillations in the HSY salivary duct cell line. | Biochimica et biophysica acta 20010528 |
| Follicle-stimulating hormone promotes the growth of human epithelial ovarian cancer cells through the protein kinase C-mediated system. | Cancer letters 20010526 |
| Effects of protein kinase C inhibitors on insulin secretory responses from rodent pancreatic islets. | Molecular and cellular endocrinology 20010525 |
| The hepatitis B virus-X protein activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade. | The Journal of biological chemistry 20010518 |
| Heterodimerization of the epidermal-growth-factor (EGF) receptor and ErbB2 and the affinity of EGF binding are regulated by different mechanisms. | The Biochemical journal 20010515 |
| Retinoic acid reduces apoptosis and oxidative stress by preservation of SOD protein level. | Free radical biology & medicine 20010515 |
| LUCA-15 suppresses CD95-mediated apoptosis in Jurkat T cells. | Oncogene 20010510 |
| Both phosphorylation and caspase-mediated cleavage contribute to regulation of the Ste20-like protein kinase Mst1 during CD95/Fas-induced apoptosis. | The Journal of biological chemistry 20010504 |
| Hyaluronidase activation of c-Jun N-terminal kinase is necessary for protection of L929 fibrosarcoma cells from staurosporine-mediated cell death. | Biochemical and biophysical research communications 20010504 |
| Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2'). | FEBS letters 20010504 |
| Mac-1-dependent tyrosine phosphorylation during neutrophil adhesion. | American journal of physiology. Cell physiology 20010501 |
| Effect of protein kinase C inhibition on hypoxic pulmonary vasoconstriction. | American journal of physiology. Lung cellular and molecular physiology 20010501 |
| NF-kappaB activation and susceptibility to apoptosis after polyamine depletion in intestinal epithelial cells. | American journal of physiology. Gastrointestinal and liver physiology 20010501 |
| A novel pharmacological action of ET-1 to prevent the cytotoxicity of doxorubicin in cardiomyocytes. | American journal of physiology. Regulatory, integrative and comparative physiology 20010501 |
| PI3K inhibitors reverse the suppressive actions of insulin on CYP2E1 expression by activating stress-response pathways in primary rat hepatocytes. | Molecular pharmacology 20010501 |
| Potential role of nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase in apoptosis and oxidative stress. | Journal of cell science 20010501 |
| Expression of P-170 glycoprotein sensitizes lymphoblastoid CEM cells to mitochondria-mediated apoptosis. | The Biochemical journal 20010501 |
| Shedding of growth hormone-binding protein is inhibited by hydroxamic acid-based protease inhibitors: proposed mechanism of activation of growth hormone-binding protein secretase. | The Journal of endocrinology 20010501 |
| High glucose inhibits renal proximal tubule cell proliferation and involves PKC, oxidative stress, and TGF-beta 1. | Kidney international 20010501 |
| Protein kinase C-mediated functional regulation of dopamine transporter is not achieved by direct phosphorylation of the dopamine transporter protein. | Journal of neurochemistry 20010501 |
| Protein kinase C regulation of dopamine transporter initiated by nicotinic receptor activation in slices of rat prefrontal cortex. | Journal of neurochemistry 20010501 |
| RB activation and repression of C-MYC transcription precede apoptosis of human prostate epithelial cells. | Urology 20010501 |
| Differential expression of 1-aminocyclopropane-1-carboxylate synthase genes during orchid flower senescence induced by the protein phosphatase inhibitor okadaic acid. | Plant physiology 20010501 |
| Role of mitogen-activated protein kinases in the differential regulation of interleukin-2 by cannabinol. | Journal of leukocyte biology 20010501 |
| Involvement of MAP kinases in the control of cPLA(2) and arachidonic acid release in endothelial cells. | Atherosclerosis 20010501 |
| Tumor necrosis factor-alpha is induced through phorbol ester--and glycated human albumin-dependent pathway in THP-1 cells. | Cellular signalling 20010501 |
| Analysis of the signal pathways involved in the regulation of fatty acid synthase gene expression by insulin and somatotropin. | Journal of animal science 20010501 |
| UCN-01 (7-hydoxystaurosporine) inhibits in vivo growth of human cancer cells through selective perturbation of G1 phase checkpoint machinery. | Japanese journal of cancer research : Gann 20010501 |
| Caspase 7 downregulation as an immunohistochemical marker of colonic carcinoma. | Human pathology 20010501 |
| A kainate receptor increases the efficacy of GABAergic synapses. | Neuron 20010501 |
| Caspase cleavage of vimentin disrupts intermediate filaments and promotes apoptosis. | Cell death and differentiation 20010501 |
| Caspases mediate nucleoporin cleavage, but not early redistribution of nuclear transport factors and modulation of nuclear permeability in apoptosis. | Cell death and differentiation 20010501 |
| Changes in starch content in oat (Avena sativa) shoot pulvini during the gravitropic response. | Journal of experimental botany 20010501 |
| Activation of tomato PR and wound-related genes by a mutagenized tomato MAP kinase kinase through divergent pathways. | Plant molecular biology 20010501 |
| Immunobiology of CD28 expression on human neutrophils. I. CD28 regulates neutrophil migration by modulating CXCR-1 expression. | European journal of immunology 20010501 |
| Activation of human neutrophils by chlordane: induction of superoxide production and phagocytosis but not chemotaxis or apoptosis. | Human & experimental toxicology 20010501 |
| Phosphorylation down-regulates the RNA binding function of the coat protein of potato virus A. | The Journal of biological chemistry 20010427 |
| Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. | Science (New York, N.Y.) 20010427 |
| Deterioration of the protein kinase C-K(ATP) channel pathway in regulation of coronary flow in hypercholesterolaemic rabbits. | European journal of pharmacology 20010427 |
| Multiple allosteric sites on muscarinic receptors. | Life sciences 20010427 |
| Two splicing variants of a new inhibitor of apoptosis gene with different biological properties and tissue distribution pattern. | FEBS letters 20010420 |
| 5-Hydroxytryptamine attenuates free radical injury in primary mouse cortical cultures. | Neuroreport 20010417 |
| Targeted inhibition of calcineurin signaling blocks calcium-dependent reactivation of Kaposi sarcoma-associated herpesvirus. | Blood 20010415 |
| Monochloramine inhibits etoposide-induced apoptosis with an increase in DNA aberration. | Free radical biology & medicine 20010415 |
| Phase I trial of 72-hour continuous infusion UCN-01 in patients with refractory neoplasms. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010415 |
| Differential mechanisms of neuroprotection by 17 beta-estradiol in apoptotic versus necrotic neurodegeneration. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20010415 |
| RGS2 blocks slow muscarinic inhibition of N-type Ca(2+) channels reconstituted in a human cell line. | The Journal of physiology 20010415 |
| An experimental test of the role of postsynaptic calcium levels in determining synaptic strength using perirhinal cortex of rat. | The Journal of physiology 20010415 |
| Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells. | The Journal of biological chemistry 20010413 |
| Phosphorylation of the N-ethylmaleimide-sensitive factor is associated with depolarization-dependent neurotransmitter release from synaptosomes. | The Journal of biological chemistry 20010413 |
| Endoplasmic reticulum localized Bcl-2 prevents apoptosis when redistribution of cytochrome c is a late event. | Oncogene 20010412 |
| An apoplastic Ca2+ sensor regulates internal Ca2+ release in aequorin-transformed tobacco cells. | The Journal of biological chemistry 20010406 |
| Gene expression profile of antithrombotic protein c defines new mechanisms modulating inflammation and apoptosis. | The Journal of biological chemistry 20010406 |
| Regulation of the G2/M transition by p53. | Oncogene 20010405 |
| Localization of human Cdc25C is regulated both by nuclear export and 14-3-3 protein binding. | Oncogene 20010405 |
| Caveolin-1 expression sensitizes fibroblastic and epithelial cells to apoptotic stimulation. | American journal of physiology. Cell physiology 20010401 |
| Regulation of SERCA Ca2+ pump expression by cytoplasmic Ca2+ in vascular smooth muscle cells. | American journal of physiology. Cell physiology 20010401 |
| Expression of myogenic constrictor tone in the aorta of hypertensive rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20010401 |
| Adenosine triphosphate activates mitogen-activated protein kinase in human granulosa-luteal cells. | Endocrinology 20010401 |
| Resistance to growth inhibitory and apoptotic effects of phorbol ester and UCN-01 in aggressive cancer cell lines. | International journal of oncology 20010401 |
| Biological activity of soluble CD100. I. The extracellular region of CD100 is released from the surface of T lymphocytes by regulated proteolysis. | Journal of immunology (Baltimore, Md. : 1950) 20010401 |
| Effect of polyamine depletion on caspase activation: a study with spermine synthase-deficient cells. | The Biochemical journal 20010401 |
| A 5-HT(7) receptor-mediated depolarization in the anterodorsal thalamus. II. Involvement of the hyperpolarization-activated current I(h). | The Journal of pharmacology and experimental therapeutics 20010401 |
| Lactoferrin: a tamoxifen-responsive protein in normal and malignant human endometrial cells in culture. | Experimental and molecular pathology 20010401 |
| Mitogenic effect of oxidized low-density lipoprotein on vascular smooth muscle cells mediated by activation of Ras/Raf/MEK/MAPK pathway. | British journal of pharmacology 20010401 |
| Down-regulation of Na-K-Cl cotransport by protein kinase C is mediated by protein phosphatase 1 in pigmented ciliary epithelial cells. | Experimental eye research 20010401 |
| Protein kinase C regulates transcription of the human guanylate cyclase C gene. | European journal of biochemistry 20010401 |
| Gonadotrophins inhibit and activin induces expression of inhibin/activin beta(B) subunit mRNA in cultured human granulosa-luteal cells. | Molecular human reproduction 20010401 |
| Abscisic acid-induced actin reorganization in guard cells of dayflower is mediated by cytosolic calcium levels and by protein kinase and protein phosphatase activities. | Plant physiology 20010401 |
| Benzene-extracted components are important for the major activity of diesel exhaust particles: effect on interleukin-8 gene expression in human bronchial epithelial cells. | American journal of respiratory cell and molecular biology 20010401 |
| MCP-1 receptor binding affinity is up-regulated by pre-stimulation with MCP-1 in an actin polymerization-dependent manner. | Journal of leukocyte biology 20010401 |
| Lysophosphatidylcholine decreases delayed rectifier K+ current in rabbit coronary smooth muscle cells. | The Journal of veterinary medical science 20010401 |
| Vitamin D compounds exert anti-apoptotic effects in human osteosarcoma cells in vitro. | The Journal of steroid biochemistry and molecular biology 20010401 |
| IL-5 priming of the PMA-induced oxidative metabolism of human eosinophils from allergic and normal subjects during a pollen season. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20010401 |
| [CDK inhibitors for therapy of cancer]. | Nihon rinsho. Japanese journal of clinical medicine 20010401 |
| Protein kinase inhibition exerts cardioprotective effects in myocardial ischemia/reperfusion via inhibition of superoxide release. | Methods and findings in experimental and clinical pharmacology 20010401 |
| Caspase-9 processing by caspase-3 via a feedback amplification loop in vivo. | Cell death and differentiation 20010401 |
| Calcium/calmodulin-dependent protein kinase inhibition potentiates thapsigargin-mediated cell death in SH-SY5Y human neuroblastoma cells. | Neuroscience letters 20010330 |
| IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or Ikappa B kinase but is blocked by Vaccinia virus E3L protein. | The Journal of biological chemistry 20010323 |
| Natural ceramide reverses Fas resistance of acid sphingomyelinase(-/-) hepatocytes. | The Journal of biological chemistry 20010316 |
| TRAF1 is a substrate of caspases activated during tumor necrosis factor receptor-alpha-induced apoptosis. | The Journal of biological chemistry 20010316 |
| Induction of the mitochondrial permeability transition mediates the killing of HeLa cells by staurosporine. | Cancer research 20010315 |
| Staurosporine and conventional anticancer drugs induce overlapping, yet distinct pathways of apoptosis and caspase activation. | Oncogene 20010308 |
| The 'in vivo' and 'ex vivo' roles of cylcooxygenase-2, nuclear factor-kappaB and protein kinases pathways in the up-regulation of B1 receptor-mediated contraction of the rabbit aorta. | Regulatory peptides 20010302 |
| TGF-beta1 inhibits caspase-3 activation and neuronal apoptosis in rat hippocampal cultures. | Neurochemistry international 20010301 |
| G-protein-coupled receptor kinase 3- and protein kinase C-mediated desensitization of the PACAP receptor type 1 in human Y-79 retinoblastoma cells. | Neuropharmacology 20010301 |
| cAMP-independent phosphorylation activation of CFTR by G proteins in native human sweat duct. | American journal of physiology. Cell physiology 20010301 |
| Protein phosphatase inhibitors facilitate DHPG-induced LTD in the CA1 region of the hippocampus. | British journal of pharmacology 20010301 |
| Phase I and pharmacokinetic study of PKC412, an inhibitor of protein kinase C. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010301 |
| Resistance to induced apoptosis in the human neuroblastoma cell line SK-N-SH in relation to neuronal differentiation. Role of Bcl-2 protein family. | European journal of biochemistry 20010301 |
| Modulation of the neuronal dopamine transporter activity by the metabotropic glutamate receptor mGluR5 in rat striatal synaptosomes through phosphorylation mediated processes. | Journal of neurochemistry 20010301 |
| Venom from the platypus, Ornithorhynchus anatinus, induces a calcium-dependent current in cultured dorsal root ganglion cells. | Journal of neurophysiology 20010301 |
| Effects of short- and long-term exposure to c-AMP and c-GMP on the noradrenaline transporter. | Neuropharmacology 20010301 |
| Nutritional lipid emulsions modulate cellular signaling and activation of human neutrophils. | Journal of lipid research 20010301 |
| A Jurkat T cell variant resistant to death receptor-induced apoptosis. Correlation with heat shock protein (Hsp) 27 and 70 levels. | European cytokine network 20010301 |
| UCN-01 suppresses E2F-1 mediated by ubiquitin-proteasome-dependent degradation. | Clinical cancer research : an official journal of the American Association for Cancer Research 20010301 |
| Staurosporine-induced apoptosis of HPV positive and negative human cervical cancer cells from different points in the cell cycle. | Cell death and differentiation 20010301 |
| Involvement of intracellular Ca2+ in the regulation of bovine leukemia virus expression. | Biological chemistry 20010301 |
| Effects of staurosporine, U-73122, wortmannin, 4-hydroxynonenal and sodium azide upon the release of secreted beta-amyloid precursor protein from human platelets in response to thrombin stimulation. | Molecular and cellular biochemistry 20010301 |
| Presence of DNA fragmentation and lack of neuroprotective effect in DFF45 knockout mice subjected to traumatic brain injury. | Molecular medicine (Cambridge, Mass.) 20010301 |
| Protein kinase C effectors bind to multidrug ABC transporters and inhibit their activity. | Biochemistry 20010227 |
| Vascular endothelial growth factor KDR receptor signaling potentiates tumor necrosis factor-induced tissue factor expression in endothelial cells. | The Journal of biological chemistry 20010216 |
| Selective targeting of a redox-active ubiquinone to mitochondria within cells: antioxidant and antiapoptotic properties. | The Journal of biological chemistry 20010216 |
| Use of protein kinase C inhibitors results in rapid [Mg(2+)](i) mobilization in primary cultured rat aortic smooth muscle cells: are certain kinase C isoforms natural homeostatic regulators of cystolic free Mg(2+). | European journal of pharmacology 20010216 |
| Arginine vasopressin inhibits apoptosis of rat glomerular mesangial cells via V1a receptors. | Life sciences 20010216 |
| Natural protection from apoptosis by surfactant protein A in type II pneumocytes. | Experimental cell research 20010215 |
| Pertussis toxin-sensitive G-protein and protein kinase C activity are involved in normal synapse elimination in the neonatal rat muscle. | Journal of neuroscience research 20010215 |
| DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells. | Cancer research 20010215 |
| Overexpression of BCL-X(L) underlies the molecular basis for resistance to staurosporine-induced apoptosis in PC-3 cells. | Cancer research 20010215 |
| Tyrosine kinase-mediated serine phosphorylation of adenylyl cyclase. | Biochemistry 20010213 |
| Expression of macrophage asialoglycoprotein-binding protein is induced through MAPK classical pathway. | Biochemical and biophysical research communications 20010209 |
| Truncated trkB.T1 is dominant negative inhibitor of trkB.TK+-mediated cell survival. | Biochemical and biophysical research communications 20010209 |
| Destabilization of neutrophil NADPH oxidase by ATP and other trinucleotides and its prevention by Mg(2+). | Biochimica et biophysica acta 20010209 |
| Hyaluronidase induction of a WW domain-containing oxidoreductase that enhances tumor necrosis factor cytotoxicity. | The Journal of biological chemistry 20010202 |
| Phosphatidic acid and diacylglycerol directly activate NADPH oxidase by interacting with enzyme components. | The Journal of biological chemistry 20010202 |
| Apoptosis-resistant mitochondria in T cells selected for resistance to Fas signaling. | The Journal of biological chemistry 20010202 |
| Neuroprotective effects of NV-31, a bilobalide-derived compound: evidence for an antioxidative mechanism. | Brain research 20010202 |
| Prosaposin treatment induces PC12 entry in the S phase of the cell cycle and prevents apoptosis: activation of ERKs and sphingosine kinase. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010201 |
| Effects of staurosporine on exocytosis and endocytosis at frog motor nerve terminals. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20010201 |
| Regulation of PDGFR-alpha in rat pulmonary myofibroblasts by staurosporine. | American journal of physiology. Lung cellular and molecular physiology 20010201 |
| Regulation of phosphate uptake in primary cultured rabbit renal proximal tubule cells by glucocorticoids: evidence for nongenomic as well as genomic mechanisms. | Endocrinology 20010201 |
| Effect of serine protease inhibitors on posttraumatic brain injury and neuronal apoptosis. | Experimental neurology 20010201 |
| Protein kinase C signaling controls skeletal muscle fiber types. | Experimental cell research 20010201 |
| Key targets for the execution of radiation-induced tumor cell apoptosis: the role of p53 and caspases. | International journal of radiation oncology, biology, physics 20010201 |
| Enzyme-linked immunosorbent assay for the determination of p21-activated kinase activity. | Journal of biochemistry 20010201 |
| Interferon-gamma protects astrocytes from apoptosis and increases the formation of p21ras-GTP complex through ras oncogene family overexpression. | Glia 20010201 |
| Effect of the overexpression of wild-type or mutant alpha-synuclein on cell susceptibility to insult. | Journal of neurochemistry 20010201 |
| Na+/K+ATPase activity inhibition and isoform-specific translocation of protein kinase C following angiotensin II administration in isolated eel enterocytes. | The Journal of endocrinology 20010201 |
| Involvement of erythropoietin-induced cytosolic free calcium mobilization in activation of mitogen-activated protein kinase and DNA synthesis in vascular smooth muscle cells. | Journal of hypertension 20010201 |
| Ischemia-induced ventricular fibrillation in isolated perfused rat heart: role of alpha1A-adrenoceptor mediated activation of protein kinase C. | Basic research in cardiology 20010201 |
| S-Phase arrest by nucleoside analogues and abrogation of survival without cell cycle progression by 7-hydroxystaurosporine. | Cancer research 20010201 |
| Signal transduction pathways through TRK-A and TRK-B receptors in human neuroblastoma cells. | Japanese journal of cancer research : Gann 20010201 |
| Characterization of adenylyl cyclases in cultured human granulosa cells. | Reproduction (Cambridge, England) 20010201 |
| Antitumor activity of benzamide riboside and its combination with cisplatin and staurosporine. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20010201 |
| Inhibition of K+ currents by homocysteine in rat ventricular myocytes. | Journal of cardiovascular electrophysiology 20010201 |
| Interactions between 2-fluoroadenine 9-beta-D-arabinofuranoside and the kinase inhibitor UCN-01 in human leukemia and lymphoma cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20010201 |
| Characteristics of the free cytosolic calcium timelag following IgE-mediated stimulation of human basophils: significance for the nonreleasing basophil phenotype. | Journal of leukocyte biology 20010201 |
| Nitrooxy alkyl apovincaminate activates K+ currents in rat neocortical neurons. | Japanese journal of pharmacology 20010201 |
| Differential activation of signal transduction pathways mediating phagocytosis, oxidative burst, and degranulation by chicken heterophils in response to stimulation with opsonized Salmonella enteritidis. | Inflammation 20010201 |
| New dermatological agents for the treatment of psoriasis. | Journal of medicinal chemistry 20010201 |
| Platelet storage lesion and apoptosis: are they related? | Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20010201 |
| Involvement of mitochondria in apoptosis. | Cardiology clinics 20010201 |
| UCN-01 Kyowa Hakko Kogyo Co. | Current opinion in investigational drugs (London, England : 2000) 20010201 |
| [Effects of hypoxia on proliferation of pulmonary arterial smooth muscle cells]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20010201 |
| Caspase-3-mediated processing of poly(ADP-ribose) glycohydrolase during apoptosis. | The Journal of biological chemistry 20010126 |
| Mechanism of hyperploid cell formation induced by microtubule inhibiting drug in glioma cell lines. | Oncogene 20010125 |
| Characterization of a rice (Oryza sativa L.) Bowman-Birk proteinase inhibitor: tightly light regulated induction in response to cut, jasmonic acid, ethylene and protein phosphatase 2A inhibitors. | Gene 20010124 |
| Aspirin promotes TFF2 gene activation in human gastric cancer cell lines. | FEBS letters 20010119 |
| Inhibitory role of regucalcin in the regulation of Ca2+ dependent protein kinases activity in rat brain neurons. | Journal of the neurological sciences 20010115 |
| Differential p53-dependent mechanism of radiosensitization in vitro and in vivo by the protein kinase C-specific inhibitor PKC412. | Cancer research 20010115 |
| Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure. | Cell 20010112 |
| Gab1 phosphorylation: a novel mechanism for negative regulation of HGF receptor signaling. | Oncogene 20010111 |
| The CEACAM1-L Ser503 residue is crucial for inhibition of colon cancer cell tumorigenicity. | Oncogene 20010111 |
| Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors? | The Journal of biological chemistry 20010105 |
| Cell autonomous apoptosis defects in acid sphingomyelinase knockout fibroblasts. | The Journal of biological chemistry 20010105 |
| Activation of dopamine D(1)-like receptor causes phosphorylation of alpha(1)-subunit of Na(+),K(+)-ATPase in rat renal proximal tubules. | European journal of pharmacology 20010105 |
| Electrical activity regulates AChR gene expression via JNK, PKCzeta and Sp1 in skeletal chick muscle. | FEBS letters 20010105 |
| Expression of intercellular adhesion molecule-1 induced by high glucose concentrations in human aortic endothelial cells. | Life sciences 20010105 |
| Differential regulation of microglial NO production by protein kinase C inhibitors. | Neurochemistry international 20010101 |
| Differential effects of bcl-2 on cell death triggered under ATP-depleting conditions. | Experimental cell research 20010101 |
| Effects of extracellular calcium and potassium on the sodium pump of rat adrenal glomerulosa cells. | American journal of physiology. Cell physiology 20010101 |
| Apoptosis enhancement by the HIV-1 Nef protein. | Journal of immunology (Baltimore, Md. : 1950) 20010101 |
| Pyrrolo-1,5-benzoxazepines induce apoptosis in chronic myelogenous leukemia (CML) cells by bypassing the apoptotic suppressor bcr-abl. | The Journal of pharmacology and experimental therapeutics 20010101 |
| Role of mitogen-activated protein kinases in activation of human neutrophils by antineutrophil cytoplasmic antibodies. | Journal of the American Society of Nephrology : JASN 20010101 |
| Lysophosphatidylcholine induces apoptosis in AR42J cells. | Pancreas 20010101 |
| Prostaglandin receptors and role of G protein-activated pathways on corpora lutea of pseudopregnant rabbit in vitro. | The Journal of endocrinology 20010101 |
| Activation of human neutrophils by technical toxaphene. | Clinical immunology (Orlando, Fla.) 20010101 |
| Growth hormone- and prolactin-induced proliferation of insulinoma cells, INS-1, depends on activation of STAT5 (signal transducer and activator of transcription 5). | Molecular endocrinology (Baltimore, Md.) 20010101 |
| Cellular distribution of constitutively active mutant parathyroid hormone (PTH)/PTH-related protein receptors and regulation of cyclic adenosine 3',5'-monophosphate signaling by beta-arrestin2. | Molecular endocrinology (Baltimore, Md.) 20010101 |
| Neurotrophin-3 mediates the autocrine survival of the catecholaminergic CAD CNS neuronal cell line. | Journal of neurochemistry 20010101 |
| The role of Bax in glutamate-induced nerve cell death. | Journal of neurochemistry 20010101 |
| Modulatory effect of protein kinase C activator on contractility of rat vas deferens. | Pharmacology 20010101 |
| DNA-dependent protein kinase catalytic subunit is cleaved during UV-induced apoptosis. | Journal of dermatological science 20010101 |
| Regulation of Bcl2 phosphorylation and potential significance for leukemic cell chemoresistance. | Journal of the National Cancer Institute. Monographs 20010101 |
| Calcitonin potentiates oxygen-glucose deprivation-induced neuronal death. | Experimental neurology 20010101 |
| High glucose stimulates Ca2+ uptake via cAMP and PLC/PKC pathways in primary cultured renal proximal tubule cells. | Kidney & blood pressure research 20010101 |
| Hemicholinium-3 mustard reveals two populations of cycling choline cotransporters in Limulus. | Neuroscience 20010101 |
| Modulation of noradrenaline-induced microvascular constriction by protein kinase inhibitors. | Naunyn-Schmiedeberg's archives of pharmacology 20010101 |
| Effects of Mannheimia haemolytica leukotoxin on apoptosis and oncosis of bovine neutrophils. | American journal of veterinary research 20010101 |
| Homocysteine stimulates the expression of monocyte chemoattractant protein-1 in endothelial cells leading to enhanced monocyte chemotaxis. | Molecular and cellular biochemistry 20010101 |
| Up-regulation of Bcl-xL in response to subtoxic beta-amyloid: role in neuronal resistance against apoptotic and oxidative injury. | Neuroscience 20010101 |
| Development of cyclin-dependent kinase modulators as novel therapeutic approaches for hematological malignancies. | Leukemia 20010101 |
| Effects of PKC inhibitors on suppression of thermotolerance development in tsAF8 cells. | International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 20010101 |
| Pharmacokinetics, distribution, metabolism and excretion of. | Cancer chemotherapy and pharmacology 20010101 |
| Non-steroidal anti-inflammatory drugs protect against chondrocyte apoptotic death. | Clinical and experimental rheumatology 20010101 |
| Abrogation of G2 checkpoint specifically sensitize p53 defective cells to cancer chemotherapeutic agents. | Anticancer research 20010101 |
| Early elicitor-induced events in chickpea cells: functional links between oxidative burst, sequential occurrence of extracellular alkalinisation and acidification, K+/H+ exchange and defence-related gene activation. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20010101 |
| Potential multidrug resistance gene POHL: an ecologically relevant indicator in marine sponges. | Environmental toxicology and chemistry 20010101 |
| Inhibition of calcium-independent luminal uptake of L-dopa by calmodulin antagonists in immortalized rat capillary cerebral endothelial cells. | Cell biology international 20010101 |
| The protein kinase activity modulation sites: mechanisms for cellular regulation - targets for therapeutic intervention. | Advances in enzyme regulation 20010101 |
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| Complex regulation of CDK2 and G1 arrest during neuronal differentiation of human prostatic cancer TSU-Prl cells by staurosporine. | Anticancer research 20010101 |
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| K-Cl cotransport: immunohistochemical and ion flux studies in human embryonic kidney (HEK293) cells transfected with full-length and C-terminal-domain-truncated KCC1 cDNAs. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20010101 |
| Bradykinin induces protein kinase C-dependent activation of phospholipase D in A-431 cells. | IUBMB life 20010101 |
| Biochemical, electron microscopic and immunohistological observations of cationic detergent-extracted cells: detection and improved preservation of microextensions and ultramicroextensions. | BMC cell biology 20010101 |
| High glucose levels alter angiotensin II-induced Ca(2+) uptake via PKC and cAMP pathways in renal proximal tubular cells. | Kidney & blood pressure research 20010101 |
| Suppressive role of endogenous regucalcin in the enhancement of protein kinase activity with proliferation of cloned rat hepatoma cells (H4-II-E). | Journal of cellular biochemistry. Supplement 20010101 |
| Activation of protein kinase C increases acetylcholine release from frog motor nerves by a direct action on L-type Ca(2+) channels and apparently not by depolarisation of the terminal. | Neuroscience 20010101 |
| Regulatory role of endogenous regucalcin in the enhancement of nuclear deoxyribonuleic acid synthesis with proliferation of cloned rat hepatoma cells (H4-II-E). | Journal of cellular biochemistry 20010101 |
| Protein kinase inhibitors can suppress stress-induced dissociation of Hsp27. | Cell stress & chaperones 20010101 |
| Ligand modulation of glial activation: cell permeable, small molecule inhibitors of serine-threonine protein kinases can block induction of interleukin 1 beta and nitric oxide synthase II. | Neurochemistry international 20010101 |
| Role of palmitoyl-protein thioesterase in cell death: implications for infantile neuronal ceroid lipofuscinosis. | European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20010101 |
| Involvement of PKC and NF-kappaB in nitric oxide induced apoptosis in human coronary artery smooth muscle cells. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20010101 |
| The effect of insulin on Na+-H+ antiport activity of obese and normal subjects erythrocytes. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20010101 |
| Structure and control of a cell-cell adhesion complex associated with spermiation in rat seminiferous epithelium. | Journal of andrology 20010101 |
| Comparison of the electromechanical responsiveness of alpha-1-adrenoceptor stimulation in ventricles of normal and cardiomyopathic hamsters. | Journal of biomedical science 20010101 |
| Effects of the PKA inhibitor H-89 on excitation-contraction coupling in skinned and intact skeletal muscle fibres. | Journal of muscle research and cell motility 20010101 |
| [Effect of protein kinase C and NO-synthase inhibitors on the radiation-induced cytogenetic adaptive response in cultured Chinese hamster cells]. | Radiatsionnaia biologiia, radioecologiia 20010101 |
| Cholesterol-induced upregulation of angiotensin II and its effects on monocyte-endothelial interaction and superoxide production. | Vascular medicine (London, England) 20010101 |
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| Novel adapter protein AP162 connects a sialyl-Le(x)-positive mucin with an apoptotic signal transduction pathway. | Glycoconjugate journal 20010101 |
| Filamin (280-kDa actin-binding protein) is a caspase substrate and is also cleaved directly by the cytotoxic T lymphocyte protease granzyme B during apoptosis. | The Journal of biological chemistry 20001215 |
| Low catecholamine concentrations protect adult rat ventricular myocytes against apoptosis through cAMP-dependent extracellular signal-regulated kinase activation. | Molecular pharmacology 20001201 |
| The super anti-apoptotic factor Bcl-xFNK constructed by disturbing intramolecular polar interactions in rat Bcl-xL. | The Journal of biological chemistry 20001124 |
| Degradation of the type I inositol 1,4,5-trisphosphate receptor by caspase-3 in SH-SY5Y neuroblastoma cells undergoing apoptosis. | Journal of neurochemistry 20001101 |
| Arsenite induces apoptosis of murine T lymphocytes through membrane raft-linked signaling for activation of c-Jun amino-terminal kinase. | Journal of immunology (Baltimore, Md. : 1950) 20001015 |
| Effector caspases are dispensable for the early nuclear morphological changes during chemical-induced apoptosis. | Journal of cell science 20000901 |
| NAIP interacts with hippocalcin and protects neurons against calcium-induced cell death through caspase-3-dependent and -independent pathways. | The EMBO journal 20000717 |
| Protein kinase inhibitors flavopiridol and 7-hydroxy-staurosporine down-regulate antiapoptosis proteins in B-cell chronic lymphocytic leukemia. | Blood 20000715 |
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| Activation of TxA2/PGH2 receptors and protein kinase C contribute to coronary dysfunction in superoxide treated rat hearts. | Journal of molecular and cellular cardiology 20000601 |
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| Microtubule/MAP-affinity regulating kinase (MARK) is activated by phenylarsine oxide in situ and phosphorylates tau within its microtubule-binding domain. | Journal of neurochemistry 20000401 |
| Deficiency of the stress kinase p38alpha results in embryonic lethality: characterization of the kinase dependence of stress responses of enzyme-deficient embryonic stem cells. | The Journal of experimental medicine 20000306 |
| Induction and regulation of xenobiotic-metabolizing cytochrome P450s in the human A549 lung adenocarcinoma cell line. | American journal of respiratory cell and molecular biology 20000301 |
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| Protein phosphatase-protein kinase interplay modulates alpha 1b-adrenoceptor phosphorylation: effects of okadaic acid. | British journal of pharmacology 20000201 |
| Mechanism of doxorubicin-induced inhibition of sarcoplasmic reticulum Ca(2+)-ATPase gene transcription. | Circulation research 20000101 |
| Actinomycin D and staurosporine, potent apoptosis inducers in vitro, are potentially effective chemotherapeutic agents against glioblastoma multiforme. | Cancer chemotherapy and pharmacology 20000101 |
| Autocrine regulation of TPA-induced apoptosis in monoblastic cell-line U-937: role for TNF-alpha, MnSOD and IL-6. | Anticancer research 20000101 |
| Comparison of the efficacy of 7-hydroxystaurosporine (UCN-01) and other staurosporine analogs to abrogate cisplatin-induced cell cycle arrest in human breast cancer cell lines. | Biochemical pharmacology 19991201 |
| Modulation of tau phosphorylation within its microtubule-binding domain by cellular thiols. | Journal of neurochemistry 19991101 |
| Characterization of MPP(+)-induced cell death in a dopaminergic neuronal cell line: role of macromolecule synthesis, cytosolic calcium, caspase, and Bcl-2-related proteins. | Experimental neurology 19990901 |
| Sequential cleavage of poly(ADP-ribose)polymerase and appearance of a small Bax-immunoreactive protein are blocked by Bcl-X(L) and caspase inhibitors during staurosporine-induced dopaminergic neuronal apoptosis. | Journal of neurochemistry 19990601 |
| Enalapril and moexipril protect from free radical-induced neuronal damage in vitro and reduce ischemic brain injury in mice and rats. | European journal of pharmacology 19990528 |
| Interferon-gamma, bacterial lipopolysaccharide, and tumor necrosis factor-alpha induce CD11a mRNA and protein via Na+/H+ exchange and protein kinase C-dependent mechanisms in tissue macrophages. | Biochemical and biophysical research communications 19990413 |
| Signaling pathway activated during apoptosis of the prostate cancer cell line LNCaP: overexpression of caspase-7 as a new gene therapy strategy for prostate cancer. | Cancer research 19990115 |
| High-throughput assay for G2 checkpoint inhibitors and identification of the structurally novel compound isogranulatimide. | Cancer research 19981215 |
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| Activation of JNK pathway and induction of apoptosis by manganese in PC12 cells. | Journal of neurochemistry 19981001 |
| Caspase-independent cell death induced by anti-CD2 or staurosporine in activated human peripheral T lymphocytes. | Journal of immunology (Baltimore, Md. : 1950) 19981001 |
| Strong expression of CD134 (OX40), a member of the TNF receptor family, in a T helper 2-type cytokine environment. | Journal of leukocyte biology 19981001 |
| Altered inotropic response of endothelin-1 in cardiomyocytes from rats with isoproterenol-induced cardiomyopathy. | Cardiovascular research 19980901 |
| Calcium/calmodulin-dependent protein kinase IV is cleaved by caspase-3 and calpain in SH-SY5Y human neuroblastoma cells undergoing apoptosis. | The Journal of biological chemistry 19980807 |
| Reduction in the radiation-induced late S phase and G2 blocks in HL-60 cell populations by amiloride, an efficient inhibitor of the Na+/H+ transporter. | Cancer research 19980201 |
| Induction of c-fos proto-oncogene in mesangial cells by cadmium. | The Journal of biological chemistry 19980102 |
| Submicromolar paclitaxel induces apoptosis in human gastric cancer cells at early G1 phase. | Anticancer research 19980101 |
| Inhibition of telomerase activity by PKC inhibitors in human nasopharyngeal cancer cells in culture. | Biochemical and biophysical research communications 19971229 |
| Activation of PKCalpha downstream from caspases during apoptosis induced by 7-hydroxystaurosporine or the topoisomerase inhibitors, camptothecin and etoposide, in human myeloid leukemia HL60 cells. | The Journal of biological chemistry 19971212 |
| Signal transduction-mediated activation of the aryl hydrocarbon receptor in rat hepatoma H4IIE cells. | The Journal of biological chemistry 19971212 |
| Involvement of caspases in sympathetic neuron apoptosis. | Journal of cell science 19970901 |
| Role of calpain- and interleukin-1 beta converting enzyme-like proteases in the beta-amyloid-induced death of rat hippocampal neurons in culture. | Journal of neurochemistry 19970401 |
| Caspase inhibition selectively reduces the apoptotic component of oxygen-glucose deprivation-induced cortical neuronal cell death. | Molecular and cellular neurosciences 19970101 |
| CD95 (APO-1/Fas) induces activation of SAP kinases downstream of ICE-like proteases. | Oncogene 19961121 |
| Inhibition of HIV-1 Tat-mediated transactivation by quinacrine and chloroquine. | Biochemical and biophysical research communications 19960904 |
| (S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-d ione (LY333531) and related analogues: isozyme selective inhibitors of protein kinase C beta. | Journal of medicinal chemistry 19960705 |
| Role of Ced-3/ICE-family proteases in staurosporine-induced programmed cell death. | The Journal of cell biology 19960601 |
| A comparison of the effects of signal transduction inhibitors on oxidative burst and degranulation in IL-I beta stimulated bovine neutrophils. | Inflammation 19951201 |
| The effects of various kinase and phosphatase inhibitors on the transmission of the prolactin and extracellular matrix signals to rabbit alpha S1-casein and transferrin genes. | The international journal of biochemistry & cell biology 19950701 |
| Regulation of the Ah gene battery via Ah receptor-dependent and independent processes in cultured adult rat hepatocytes. | Drug metabolism and disposition: the biological fate of chemicals 19950601 |
| Evidence for a role of endothelin 1 and protein kinase C in nitroglycerin tolerance. | Proceedings of the National Academy of Sciences of the United States of America 19950523 |
| Identification of a second region upstream of the mouse heme oxygenase-1 gene that functions as a basal level and inducer-dependent transcription enhancer. | The Journal of biological chemistry 19950519 |
| Differential inhibition of cytosolic and membrane-derived protein kinase C activity by staurosporine and other kinase inhibitors. | FEBS letters 19950403 |
| Aluminum-induced DNA synthesis in osteoblasts: mediation by a G-protein coupled cation sensing mechanism. | Journal of cellular biochemistry 19940901 |
| Differential inhibition of protein kinase C isozymes by UCN-01, a staurosporine analogue. | Molecular pharmacology 19940601 |
| Acetaldehyde induces c-fos and c-jun proto-oncogenes in fat-storing cell cultures through protein kinase C activation. | Alcohol and alcoholism (Oxford, Oxfordshire) 19940501 |
| The phorbol ester phorbol myristate acetate inhibits human immunodeficiency virus type 1 envelope-mediated fusion by modulating an accessory component(s) in CD4-expressing cells. | Journal of virology 19940301 |
| Modulation of 1-[beta-D-arabinofuranosyl] cytosine-induced apoptosis in human myeloid leukemia cells by staurosporine and other pharmacological inhibitors of protein kinase C. | Oncology research 19940101 |
| Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C. | The Biochemical journal 19930901 |
| Differentiation of human monoblastic leukemia U937 cells induced by inhibitors of myosin light chain kinase and prevention of differentiation by granulocyte-macrophage colony-stimulating factor. | Biochimica et biophysica acta 19930416 |
| Effect of various protein kinase inhibitors on the induction of milk protein gene expression by prolactin. | Molecular and cellular endocrinology 19930301 |
| Anti-inflammatory properties of the protein kinase C inhibitor, 3-[1-[3-(dimethylamino)propyl]-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H- pyrrole-2,5-dione monohydrochloride (GF109203X) in the PMA-mouse ear edema model. | Agents and actions 19930101 |
| Bradykinin-induced activation of nociceptors: receptor and mechanistic studies on the neonatal rat spinal cord-tail preparation in vitro. | British journal of pharmacology 19921201 |
| Dioxin-dependent activation of murine Cyp1a-1 gene transcription requires protein kinase C-dependent phosphorylation. | Molecular and cellular biology 19920401 |
| Nerve growth factor-stimulated calcium uptake into PC12 cells: uniqueness of the channel and evidence for phosphorylation. | Journal of neuroscience research 19920401 |
| Heparin selectively inhibits the transcription of tissue-type plasminogen activator in primate arterial smooth muscle cells during mitogenesis. | The Journal of biological chemistry 19920215 |
| Specific inhibition of cytoplasmic protein tyrosine kinases by herbimycin A in vitro. | Biochemical pharmacology 19911009 |
| The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. | The Journal of biological chemistry 19910825 |
| Effects of staurosporine on the pressor responses to alpha-adrenoceptor agonists in pithed rats: a comparison with nifedipine. | Pharmacology 19910101 |
| Augmentation of cytotoxic effect of tumor necrosis factor on human immunodeficiency virus-infected cells by staurosporine, a potent protein kinase C inhibitor. | Cancer research 19900901 |
| The phorbol ester TPA strongly inhibits HIV-1-induced syncytia formation but enhances virus production: possible involvement of protein kinase C pathway. | Virology 19900501 |
| A novel mechanism of action of corticotropin releasing factor in rat Leydig cells. | The Journal of biological chemistry 19900205 |
| Phorbol ester-mediated induction of HIV-1 from a chronically infected promonocyte clone: blockade by protein kinase inhibitors and relationship to tat-directed trans-activation. | Biochemical and biophysical research communications 19900115 |
| Comparison of effects of protein kinase C inhibitors on phorbol ester-induced CD4 down-regulation and augmentation of human immunodeficiency virus replication in human T cell lines. | Biochemical and biophysical research communications 19891016 |
| A further comparison of insulin- and phorbol ester-stimulated glucose transport in adipocytes. | Molecular and cellular endocrinology 19890801 |
| Membrane-bound protein kinase C modulates receptor affinity and chemotactic responsiveness of Lewis lung carcinoma sublines to an elastin-derived peptide. | The Journal of biological chemistry 19890625 |
| Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases. | Trends in pharmacological sciences 19890601 |
| The action of the protein kinase C inhibitor, staurosporine, on human platelets. Evidence against a regulatory role for protein kinase C in the formation of inositol trisphosphate by thrombin. | The Biochemical journal 19880115 |
| UCN-01, a selective inhibitor of protein kinase C from Streptomyces. | The Journal of antibiotics 19871201 |
| Staurosporine, a potent inhibitor of phospholipid/Ca++dependent protein kinase. | Biochemical and biophysical research communications 19860313 |
| A new alkaloid AM-2282 OF Streptomyces origin. Taxonomy, fermentation, isolation and preliminary characterization. | The Journal of antibiotics 19770401 |