1-((3R,5S,8R,9S,10S,13S,14S,17S)-3-Hydroxy-3,10,13-trimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethanone
| Title | Journal |
|---|---|
| Effect of ganaxolone and THIP on operant and limited-access ethanol self-administration. | Neuropharmacology 20120901 |
| Modulation of spinal GABAergic analgesia by inhibition of chloride extrusion capacity in mice. | The journal of pain : official journal of the American Pain Society 20120601 |
| Recent and future antiepileptic drugs and their impact on cognition: what can we expect? | Expert review of neurotherapeutics 20120601 |
| Pharmacological treatment of fragile X syndrome with GABAergic drugs in a knockout mouse model. | Behavioural brain research 20120401 |
| Epilepsy: Novel therapeutic targets. | Journal of pharmacology & pharmacotherapeutics 20120101 |
| Neurosteroid influences on sensitivity to ethanol. | Frontiers in endocrinology 20120101 |
| Alteration of ethanol drinking in mice via modulation of the GABA(A) receptor with ganaxolone, finasteride, and gaboxadol. | Alcoholism, clinical and experimental research 20111101 |
| Fragile x syndrome. | Current genomics 20110501 |
| Pharmacotherapy of epilepsy: newly approved and developmental agents. | CNS drugs 20110201 |
| Neurosteroids and GABA(A) Receptor Interactions: A Focus on Stress. | Frontiers in neuroscience 20110101 |
| Neuroprotective actions of neurosteroids. | Frontiers in endocrinology 20110101 |
| Role of anticonvulsant and antiepileptogenic neurosteroids in the pathophysiology and treatment of epilepsy. | Frontiers in endocrinology 20110101 |
| Neurosteroids and GABA-A Receptor Function. | Frontiers in endocrinology 20110101 |
| Neurosteroids as neuromodulators in the treatment of anxiety disorders. | Frontiers in endocrinology 20110101 |
| Pregnenolone and ganaxolone reduce operant ethanol self-administration in alcohol-preferring p rats. | Alcoholism, clinical and experimental research 20101201 |
| Progress report on new antiepileptic drugs: a summary of the Tenth Eilat Conference (EILAT X). | Epilepsy research 20101201 |
| 'Epileptic encephalopathy' of infancy and childhood: electro-clinical pictures and recent understandings. | Current neuropharmacology 20101201 |
| Emerging drugs for partial onset seizures. | Expert opinion on emerging drugs 20100901 |
| Ganaxolone suppression of behavioral and electrographic seizures in the mouse amygdala kindling model. | Epilepsy research 20100501 |
| Neurosteroids and epilepsy. | Current opinion in neurology 20100401 |
| Anticonvulsant doses of ganaxolone do not compromise motor performance in immature rats. | Neuroscience letters 20100129 |
| Anticonvulsant action of a new analogue of allopregnanolone in immature rats. | Physiological research 20100101 |
| Fragile X and autism: Intertwined at the molecular level leading to targeted treatments. | Molecular autism 20100101 |
| Neurosteroids: endogenous role in the human brain and therapeutic potentials. | Progress in brain research 20100101 |
| Hormonal aspects of epilepsy. | Neurologic clinics 20091101 |
| Neurosteroid replacement therapy for catamenial epilepsy. | Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20090401 |
| Progress report on new antiepileptic drugs: a summary of the Ninth Eilat Conference (EILAT IX). | Epilepsy research 20090101 |
| Third-generation antiepileptic drugs: mechanisms of action, pharmacokinetics and interactions. | Pharmacological reports : PR 20090101 |
| Current trends in the treatment of infantile spasms. | Neuropsychiatric disease and treatment 20090101 |
| Treatment of Lennox-Gastaut syndrome: overview and recent findings. | Neuropsychiatric disease and treatment 20081201 |
| Endogenous and synthetic neurosteroids in treatment of Niemann-Pick Type C disease. | Brain research reviews 20080301 |
| Role of brain inflammation in epileptogenesis. | Yonsei medical journal 20080227 |
| Modifications of antiepileptic drugs for improved tolerability and efficacy. | Perspectives in medicinal chemistry 20080101 |
| Clinical evaluation of ganaxolone in pediatric and adolescent patients with refractory epilepsy. | Epilepsia 20071001 |
| [A new aspect in the research on antiepileptic drugs]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20070201 |
| Progress report on new antiepileptic drugs: a summary of the Eigth Eilat Conference (EILAT VIII). | Epilepsy research 20070101 |
| Ganaxolone. | Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20070101 |
| Diverse mechanisms of antiepileptic drugs in the development pipeline. | Epilepsy research 20060601 |
| Effects of some neurosteroids injected into some brain areas of WAG/Rij rats, an animal model of generalized absence epilepsy. | Neuropharmacology 20060601 |
| Allopregnanolone and ganaxolone increase the firing activity of dorsal raphe nucleus serotonergic neurons in female rats. | The international journal of neuropsychopharmacology 20060401 |
| [Perspectives of neurosteroid derivative application in antiepileptic therapy]. | Przeglad lekarski 20050101 |
| Role of neurosteroids in catamenial epilepsy. | Epilepsy research 20041201 |
| Pharmacology of catamenial epilepsy. | Methods and findings in experimental and clinical pharmacology 20040901 |
| Allopregnanolone analogs that positively modulate GABA receptors protect against partial seizures induced by 6-Hz electrical stimulation in mice. | Epilepsia 20040701 |
| The contraceptive agent Provera enhances GABA(A) receptor-mediated inhibitory neurotransmission in the rat hippocampus: evidence for endogenous neurosteroids? | The Journal of neuroscience : the official journal of the Society for Neuroscience 20031105 |
| Catamenial epilepsy: pathophysiology, diagnosis, and management. | Neurology 20030901 |
| Protective efficacy of neuroactive steroids against cocaine kindled-seizures in mice. | European journal of pharmacology 20030808 |
| Pharmacology of endogenous neuroactive steroids. | Critical reviews in neurobiology 20030101 |
| Changes in GABA(A) receptor gene expression induced by withdrawal of, but not by long-term exposure to, ganaxolone in cultured rat cerebellar granule cells. | The Journal of pharmacology and experimental therapeutics 20021201 |
| Newer GABAergic agents for pharmacotherapy of infantile spasms. | Drugs of today (Barcelona, Spain : 1998) 20021001 |
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
| Neurosteroids and infantile spasms: the deoxycorticosterone hypothesis. | International review of neurobiology 20020101 |
| Early postnatal ethanol intubation blunts GABA(A) receptor up-regulation and modifies 3alpha-hydroxy-5alpha-pregnan-20-one sensitivity in rat MS/DB neurons. | Brain research. Developmental brain research 20010923 |
| A high-performance liquid chromatography-tandem mass spectrometric method for the determination of pharmacokinetics of ganaxolone in rat, monkey, dog and human plasma. | Journal of chromatography. B, Biomedical sciences and applications 20010210 |
| The new generation of GABA enhancers. Potential in the treatment of epilepsy. | CNS drugs 20010101 |
| Future prospects for the drug treatment of epilepsy. | CNS drugs 20010101 |
| Anticonvulsant and behavioral effects of neuroactive steroids alone and in conjunction with diazepam. | The Journal of pharmacology and experimental therapeutics 19970801 |