Abiraterone Acetate
Title | Journal |
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Differential response to abiraterone acetate and di-n-butyl phthalate in an androgen-sensitive human fetal testis xenograft bioassay. | Toxicological sciences : an official journal of the Society of Toxicology 20140301 |
Changing paradigms in management of metastatic Castration Resistant Prostate Cancer (mCRPC). | BMC urology 20140101 |
Urologists and oncologists: adapting to a new treatment paradigm in castration-resistant prostate cancer (CRPC). | BJU international 20120801 |
Effect of abiraterone acetate plus prednisone on the QT interval in patients with metastatic castration-resistant prostate cancer. | Cancer chemotherapy and pharmacology 20120801 |
Abiraterone inhibits 3β-hydroxysteroid dehydrogenase: a rationale for increasing drug exposure in castration-resistant prostate cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120701 |
Discovery of potent and orally bioavailable 17β-hydroxysteroid dehydrogenase type 3 inhibitors. | Bioorganic & medicinal chemistry 20120515 |
Novel molecular targets for the therapy of castration-resistant prostate cancer. | European urology 20120501 |
Beyond castration-defining future directions in the hormonal treatment of prostate cancer. | Hormones & cancer 20120401 |
Abiraterone acetate: redefining hormone treatment for advanced prostate cancer. | Drug discovery today 20120301 |
Advances in the management of high-risk localised and metastatic prostate cancer. | BJU international 20120301 |
Abiraterone acetate: a guide to its use in metastatic castration-resistant prostate cancer. | Drugs & aging 20120301 |
The 5α-androstanedione pathway to dihydrotestosterone in castration-resistant prostate cancer. | Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20120201 |
Development and clinical utility of abiraterone acetate as an androgen synthesis inhibitor. | Clinical pharmacology and therapeutics 20120101 |
Abiraterone acetate, a first-in-class CYP17 inhibitor, establishes a new treatment paradigm in castration-resistant prostate cancer. | Expert review of anticancer therapy 20120101 |
Abiraterone acetate: oral androgen biosynthesis inhibitor for treatment of castration-resistant prostate cancer. | Drug design, development and therapy 20120101 |
Optimizing outcomes of advanced prostate cancer: drug sequencing and novel therapeutic approaches. | Oncology (Williston Park, N.Y.) 20120101 |
Successful Treatment of Advanced Metastatic Prostate Cancer following Chemotherapy Based on Molecular Profiling. | Case reports in oncology 20120101 |
Drugs in traffic: the road to approval. | Nature medicine 20111206 |
TMPRSS2-ERG status in circulating tumor cells as a predictive biomarker of sensitivity in castration-resistant prostate cancer patients treated with abiraterone acetate. | European urology 20111101 |
Circulating tumour cells as surrogate biomarkers in castration-resistant prostate cancer trials. | European urology 20111101 |
Clinical implications of the 5α-androstanedione pathway for castration-resistant prostate cancer. | Future oncology (London, England) 20111101 |
Abiraterone acetate: in metastatic castration-resistant prostate cancer. | Drugs 20111022 |
Flushing oral oncology drugs down the toilet. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20111020 |
Abiraterone acetate for prostate cancer: a new era of hormonal therapies. | Asian journal of andrology 20110901 |
Phase II study of abiraterone acetate in chemotherapy-naive metastatic castration-resistant prostate cancer displaying bone flare discordant with serologic response. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110715 |
[The trend toward development of novel agents based on the mechanism of prostate cancer progression]. | Nihon rinsho. Japanese journal of clinical medicine 20110601 |
CYP17 inhibitors for prostate cancer therapy. | The Journal of steroid biochemistry and molecular biology 20110501 |
Roflumilast, indacaterol maleate, and abiraterone acetate. | Journal of the American Pharmacists Association : JAPhA 20110101 |
Abiraterone acetate. | Drugs in R&D 20101101 |
CYP17 inhibition as a hormonal strategy for prostate cancer. | Nature clinical practice. Urology 20081101 |
Synthesis, biological evaluation, and molecular modeling studies of methylene imidazole substituted biaryls as inhibitors of human 17alpha-hydroxylase-17,20-lyase (CYP17)--part II: Core rigidification and influence of substituents at the methylene bridge. | Bioorganic & medicinal chemistry 20080815 |
Synthesis, biological evaluation and molecular modelling studies of methyleneimidazole substituted biaryls as inhibitors of human 17alpha-hydroxylase-17,20-lyase (CYP17). Part I: Heterocyclic modifications of the core structure. | Bioorganic & medicinal chemistry 20080215 |
Hormonal impact of the 17alpha-hydroxylase/C(17,20)-lyase inhibitor abiraterone acetate (CB7630) in patients with prostate cancer. | British journal of cancer 20040614 |
Novel steroidal inhibitors of human cytochrome P45017 alpha (17 alpha-hydroxylase-C17,20-lyase): potential agents for the treatment of prostatic cancer. | Journal of medicinal chemistry 19950623 |