Irinotecan
| Title | Journal |
|---|---|
| Plasma citrulline is a sensitive safety biomarker for small intestinal injury in rats. | Toxicology letters 20181001 |
| Impact of diet on irinotecan toxicity in mice. | Chemico-biological interactions 20180801 |
| Dual effect of silymarin on experimental non-alcoholic steatohepatitis induced by irinotecan. | Toxicology and applied pharmacology 20170715 |
| Role of Toll-like receptor 4 in drug-drug interaction between paclitaxel and irinotecan in vitro. | Toxicology in vitro : an international journal published in association with BIBRA 20170601 |
| Inhibition of NF-κB and metastasis in irinotecan (CPT-11)-resistant LoVo colon cancer cells by thymoquinone via JNK and p38. | Environmental toxicology 20170201 |
| Carvacrol reduces irinotecan-induced intestinal mucositis through inhibition of inflammation and oxidative damage via TRPA1 receptor activation. | Chemico-biological interactions 20161225 |
| OTX015 (MK-8628), a novel BET inhibitor, displays in vitro and in vivo antitumor effects alone and in combination with conventional therapies in glioblastoma models. | International journal of cancer 20161101 |
| The clinical development candidate CCT245737 is an orally active CHK1 inhibitor with preclinical activity in RAS mutant NSCLC and Eµ-MYC driven B-cell lymphoma. | Oncotarget 20160119 |
| Irinotecan (CPT-11)-induced elevation of bile acids potentiates suppression of IL-10 expression. | Toxicology and applied pharmacology 20160115 |
| CPT-11 activates NLRP3 inflammasome through JNK and NF-κB signalings. | Toxicology and applied pharmacology 20151201 |
| Arsenic sulfide combined with JQ1, chemotherapy agents, or celecoxib inhibit gastric and colon cancer cell growth. | Drug design, development and therapy 20150101 |
| ATR inhibitors VE-821 and VX-970 sensitize cancer cells to topoisomerase i inhibitors by disabling DNA replication initiation and fork elongation responses. | Cancer research 20141201 |
| P-glycoprotein, CYP3A, and plasma carboxylesterase determine brain and blood disposition of the mTOR Inhibitor everolimus (Afinitor) in mice. | Clinical cancer research : an official journal of the American Association for Cancer Research 20140615 |
| A simple transcriptomic signature able to predict drug-induced hepatic steatosis. | Archives of toxicology 20140401 |
| Synergism of cyclin-dependent kinase inhibitors with camptothecin derivatives in small cell lung cancer cell lines. | Molecules (Basel, Switzerland) 20140217 |
| Optimization of irinotecan chronotherapy with P-glycoprotein inhibition. | Toxicology and applied pharmacology 20140201 |
| Incidence of contrast-induced nephropathy in hospitalised patients with cancer. | European radiology 20140101 |
| Intestinal glucuronidation protects against chemotherapy-induced toxicity by irinotecan (CPT-11). | Proceedings of the National Academy of Sciences of the United States of America 20131119 |
| Epigenetic regulation is a crucial factor in the repression of UGT1A1 expression in the human kidney. | Drug metabolism and disposition: the biological fate of chemicals 20131001 |
| Identification of cyclohexanone derivatives that act as catalytic inhibitors of topoisomerase I: effects on tamoxifen-resistant MCF-7 cancer cells. | Investigational new drugs 20121201 |
| Bevacizumab in combination with irinotecan, 5-fluorouracil, and leucovorin (FOLFIRI) in patients with metastatic colorectal cancer who were previously treated with oxaliplatin-containing regimens: a multicenter observational cohort study (TCTG 2nd-BV study). | Medical oncology (Northwood, London, England) 20121201 |
| Combination of ATP-competitive mammalian target of rapamycin inhibitors with standard chemotherapy for colorectal cancer. | Investigational new drugs 20121201 |
| Fabrication of biodegradable micelles with sheddable poly(ethylene glycol) shells as the carrier of 7-ethyl-10-hydroxy-camptothecin. | Colloids and surfaces. B, Biointerfaces 20121201 |
| Molecular structure and vibrational spectra of Irinotecan: a density functional theoretical study. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121201 |
| A meta-analysis of bevacizumab alone and in combination with irinotecan in the treatment of patients with recurrent glioblastoma multiforme. | Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20121201 |
| A combination of liposomal sunitinib plus liposomal irinotecan and liposome co-loaded with two drugs enhanced antitumor activity in PC12-bearing mouse. | Journal of drug targeting 20121201 |
| Discovery of 3-alkoxyamino-5-(pyridin-2-ylamino)pyrazine-2-carbonitriles as selective, orally bioavailable CHK1 inhibitors. | Journal of medicinal chemistry 20121126 |
| BBA, a derivative of 23-hydroxybetulinic acid, potently reverses ABCB1-mediated drug resistance in vitro and in vivo. | Molecular pharmaceutics 20121105 |
| Systemic treatment of advanced pancreatic cancer. | Cancer treatment reviews 20121101 |
| Relapsed hepatoblastoma. | Pediatric blood & cancer 20121101 |
| Chemotherapeutic approaches for newly diagnosed hepatoblastoma: past, present, and future strategies. | Pediatric blood & cancer 20121101 |
| A randomized phase II study of irinotecan plus cisplatin versus irinotecan plus capecitabine with or without isosorbide-5-mononitrate in advanced non-small-cell lung cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20121101 |
| Comparative studies of irinotecan-loaded polyethylene glycol-modified liposomes prepared using different PEG-modification methods. | Biochimica et biophysica acta 20121101 |
| The synergistic effects of low-dose irinotecan and TRAIL on TRAIL-resistant HT-29 colon carcinoma in vitro and in vivo. | International journal of molecular medicine 20121101 |
| In vivo real-time imaging of chemotherapy response on the liver metastatic tumor microenvironment using multiphoton microscopy. | Oncology reports 20121101 |
| Phase I/II study of S-1 combined with biweekly irinotecan chemotherapy in previously treated advanced non-small cell lung cancer. | Cancer chemotherapy and pharmacology 20121101 |
| Phase I and pharmacokinetic study of IHL-305 (PEGylated liposomal irinotecan) in patients with advanced solid tumors. | Cancer chemotherapy and pharmacology 20121101 |
| Phase II study of irinotecan and cisplatin with concurrent split-course radiotherapy in limited-disease small cell lung cancer. | Cancer chemotherapy and pharmacology 20121101 |
| Lack of efficacy of bevacizumab + irinotecan in cases of pediatric recurrent ependymoma--a Pediatric Brain Tumor Consortium study. | Neuro-oncology 20121101 |
| CCT244747 is a novel potent and selective CHK1 inhibitor with oral efficacy alone and in combination with genotoxic anticancer drugs. | Clinical cancer research : an official journal of the American Association for Cancer Research 20121015 |
| Camptothecins in tumor homing via an RGD sequence mimetic. | Bioorganic & medicinal chemistry letters 20121015 |
| Primary hepatic leiomyosarcoma with liver metastasis of rectal cancer. | World journal of gastroenterology 20121014 |
| Creation of pure nanodrugs and their anticancer properties. | Angewandte Chemie (International ed. in English) 20121008 |
| Irinotecan induces senescence and apoptosis in colonic cells in vitro. | Toxicology letters 20121002 |
| Discontinuation of bevacizumab and FOLFIRI administered up to a maximum of 12 cycles as first-line therapy for metastatic colorectal cancer: a retrospective Italian study. | Investigational new drugs 20121001 |
| Pharmacodynamic evaluation of irinotecan therapy by FDG and FLT PET/CT imaging in a colorectal cancer xenograft model. | Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20121001 |
| Evaluation of combined bevacizumab plus irinotecan therapy in brain tumors using magnetic resonance imaging measures of relative cerebral blood volume. | Magnetic resonance in medicine 20121001 |
| Second-line chemotherapy for advanced gastric cancer in Korea. | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20121001 |
| UPLC and LC-MS studies on degradation behavior of irinotecan hydrochloride and development of a validated stability-indicating ultra-performance liquid chromatographic method for determination of irinotecan hydrochloride and its impurities in pharmaceutical dosage forms. | Journal of chromatographic science 20121001 |
| Gef gene therapy enhances the therapeutic efficacy of cytotoxics in colon cancer cells. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20121001 |
| Preparation and in vitro characterization of SN-38-loaded, self-forming polymeric depots as an injectable drug delivery system. | Journal of pharmaceutical sciences 20121001 |
| Characterization of a large panel of patient-derived tumor xenografts representing the clinical heterogeneity of human colorectal cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20121001 |
| Species difference of esterase expression and hydrolase activity in plasma. | Journal of pharmaceutical sciences 20121001 |
| Aspirin as adjuvant therapy for colorectal cancer--reinterpreting paradigms. | Nature reviews. Clinical oncology 20121001 |
| Phase I/II study of radiologic hepatic arterial infusion of fluorouracil plus systemic irinotecan for unresectable hepatic metastases from colorectal cancer: Japan Clinical Oncology Group Trial 0208-DI. | Journal of vascular and interventional radiology : JVIR 20121001 |
| Addition of aflibercept to fluorouracil, leucovorin, and irinotecan improves survival in a phase III randomized trial in patients with metastatic colorectal cancer previously treated with an oxaliplatin-based regimen. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20121001 |
| TAS-102 monotherapy for pretreated metastatic colorectal cancer: a double-blind, randomised, placebo-controlled phase 2 trial. | The Lancet. Oncology 20121001 |
| Liquid chromatography-tandem mass spectrometry method for simultaneous determination of seven commonly used anticancer drugs in human plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20121001 |
| Dose banding as an alternative to body surface area-based dosing of chemotherapeutic agents. | British journal of cancer 20120925 |
| New tricks for an old natural product: discovery of highly potent evodiamine derivatives as novel antitumor agents by systemic structure-activity relationship analysis and biological evaluations. | Journal of medicinal chemistry 20120913 |
| Multi-institutional experience with FOLFIRINOX in pancreatic adenocarcinoma. | JOP : Journal of the pancreas 20120910 |
| FOLFIRI regimen in metastatic pancreatic adenocarcinoma resistant to gemcitabine and platinum-salts. | World journal of gastroenterology 20120907 |
| Microsatellite instability in metastatic colorectal cancer: a review of pathology, response to chemotherapy and clinical outcome. | Medical oncology (Northwood, London, England) 20120901 |
| Combination of irinotecan and 5-fluorouracil with radiation in locally advanced rectal adenocarcinoma. | Journal of gastrointestinal cancer 20120901 |
| Treatment decisions after diagnosis of metastatic colorectal cancer. | Clinical colorectal cancer 20120901 |
| Chemotherapy for the biliary tract cancers: moving toward improved survival time. | Journal of gastrointestinal cancer 20120901 |
| Oxaliplatin in combination with infusional 5-fluorouracil as first-line chemotherapy for elderly patients with metastatic colorectal cancer: a phase II study of the Spanish Cooperative Group for the Treatment of Digestive Tumors. | Clinical colorectal cancer 20120901 |
| Anti-EGFR (cetuximab) combined with irinotecan for treatment of elderly patients with metastatic colorectal cancer (mCRC). | Journal of cancer research and clinical oncology 20120901 |
| N-glycan biosynthesis inhibitors induce in vitro anticancer activity in colorectal cancer cells. | Journal of cellular biochemistry 20120901 |
| Phase II study of combined chemotherapy with irinotecan and S-1 (IRIS) plus bevacizumab in patients with inoperable recurrent or advanced colorectal cancer. | Acta oncologica (Stockholm, Sweden) 20120901 |
| Personalized medicine: potential, barriers and contemporary issues. | Current drug metabolism 20120901 |
| Progression while receiving preoperative chemotherapy should not be an absolute contraindication to liver resection for colorectal metastases. | Annals of surgical oncology 20120901 |
| AZ64 inhibits TrkB and enhances the efficacy of chemotherapy and local radiation in neuroblastoma xenografts. | Cancer chemotherapy and pharmacology 20120901 |
| Preparation of irinotecan-loaded folate-targeted liposome for tumor targeting delivery and its antitumor activity. | AAPS PharmSciTech 20120901 |
| Theranostic nanoparticles based on PEGylated hyaluronic acid for the diagnosis, therapy and monitoring of colon cancer. | Biomaterials 20120901 |
| MET increases the sensitivity of gefitinib-resistant cells to SN-38, an active metabolite of irinotecan, by up-regulating the topoisomerase I activity. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20120901 |
| Outcome of first line systemic treatment in elderly compared to younger patients with metastatic colorectal cancer: a retrospective analysis of the CAIRO and CAIRO2 studies of the Dutch Colorectal Cancer Group (DCCG). | Acta oncologica (Stockholm, Sweden) 20120901 |
| S-1 for the treatment of gastrointestinal cancer. | Expert opinion on pharmacotherapy 20120901 |
| SMARCAL1 deficiency predisposes to non-Hodgkin lymphoma and hypersensitivity to genotoxic agents in vivo. | American journal of medical genetics. Part A 20120901 |
| Evaluation of predictive markers for patients with advanced colorectal cancer. | Acta oncologica (Stockholm, Sweden) 20120901 |
| Influcence of localization of primary tumor on effectiveness of 5-fluorouracil/leucovorin combined with irinotecan and oxaliplatin (FOLFIRINOX) in patients with metastatic pancreatic adenocarcinoma: a retrospective study. | Anticancer research 20120901 |
| Long-term results of a phase II study of S-1 plus irinotecan in metastatic colorectal cancer. | Anticancer research 20120901 |
| [Efficacy assessments for chemotherapy and timing of changing treatment in gastric cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20120901 |
| [A patient with gastric small cell carcinoma who died from meningitis carcinomatosa after CDDP+CPT-11 chemotherapy with good response]. | Gan to kagaku ryoho. Cancer & chemotherapy 20120901 |
| [A case of poorly-differentiated neuroendocrine carcinoma of the ascending colon with multiple liver metastases successfully treated with cisplatin and irinotecan]. | Gan to kagaku ryoho. Cancer & chemotherapy 20120901 |
| [A case of large cell neuroendocrine carcinoma (LCNEC) of the uterine cervix successfully treated by postoperative CPT-11+CDDP chemotherapy after non-curative surgery]. | Gan to kagaku ryoho. Cancer & chemotherapy 20120901 |
| [Use of angioneogenesis inhibitor monoclonal antibody following standard therapy in recurrent or progressive glioblastoma multiforme]. | Magyar onkologia 20120901 |
| Constitutive Expression of MAP Kinase Phosphatase-1 Confers Multi-drug Resistance in Human Glioblastoma Cells. | Cancer research and treatment : official journal of Korean Cancer Association 20120901 |
| Intrapatient cetuximab dose escalation in metastatic colorectal cancer according to the grade of early skin reactions: the randomized EVEREST study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120810 |
| Biweekly cetuximab plus irinotecan as second-line chemotherapy for patients with irinotecan-refractory and KRAS wild-type metastatic colorectal cancer according to epidermal growth factor receptor expression status. | Investigational new drugs 20120801 |
| A single-arm pilot phase II study of gefitinib and irinotecan in children with newly diagnosed high-risk neuroblastoma. | Investigational new drugs 20120801 |
| Phase II study of oral S-1 with irinotecan and bevacizumab (SIRB) as first-line therapy for patients with metastatic colorectal cancer. | Investigational new drugs 20120801 |
| Biologic therapies in the metastatic colorectal cancer treatment continuum--applying current evidence to clinical practice. | Cancer treatment reviews 20120801 |
| What is a safe future liver remnant size in patients undergoing major hepatectomy for colorectal liver metastases and treated by intensive preoperative chemotherapy? | Annals of surgical oncology 20120801 |
| Irinotecan drug-eluting beads in the treatment of chemo-naive unresectable colorectal liver metastasis with concomitant systemic fluorouracil and oxaliplatin: results of pharmacokinetics and phase I trial. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20120801 |
| Potential repurposing of known drugs as potent bacterial β-glucuronidase inhibitors. | Journal of biomolecular screening 20120801 |
| First-line sunitinib plus FOLFIRI in Japanese patients with unresectable/metastatic colorectal cancer: a phase II study. | Cancer science 20120801 |
| Phase II study of maintenance sunitinib following irinotecan and carboplatin as first-line treatment for patients with extensive-stage small-cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20120801 |
| Chemotherapy for pulmonary large cell neuroendocrine carcinoma: similar to that for small cell lung cancer or non-small cell lung cancer? | Lung cancer (Amsterdam, Netherlands) 20120801 |
| Phase II study of neoadjuvant chemotherapy with irinotecan hydrochloride and nedaplatin followed by radical hysterectomy for bulky stage Ib2 to IIb, cervical squamous cell carcinoma: Japanese Gynecologic Oncology Group study (JGOG 1065). | Oncology reports 20120801 |
| Pharmacogenomic profiling and pathway analyses identify MAPK-dependent migration as an acute response to SN38 in p53 null and p53-mutant colorectal cancer cells. | Molecular cancer therapeutics 20120801 |
| The role of natural killer cells in combinatorial anti-cancer therapy using Sindbis viral vectors and irinotecan. | Cancer gene therapy 20120801 |
| Modified FOLFOX-6 therapy for heavily pretreated advanced gastric cancer refractory to fluorouracil, irinotecan, cisplatin and taxanes: a retrospective study. | Japanese journal of clinical oncology 20120801 |
| Cetuximab in the first-line treatment of K-ras wild-type metastatic colorectal cancer: the choice and schedule of fluoropyrimidine matters. | Cancer chemotherapy and pharmacology 20120801 |
| Feasibility and efficacy of combined cisplatin and irinotecan chemotherapy for poorly differentiated neuroendocrine carcinomas. | Japanese journal of clinical oncology 20120801 |
| Current and future management strategies for relapsed or progressive hepatoblastoma. | Paediatric drugs 20120801 |
| Phase II study of cisplatin with irinotecan as induction chemotherapy followed by chemoradiotherapy for unresectable stage III non-small cell lung cancer. | Anticancer research 20120801 |
| Association between COX-2 expression and effectiveness of COX-2 inhibitors in a phase II trial in patients with metastatic colorectal adenocarcinoma. | Anticancer research 20120801 |
| Applicability of histoculture drug response assays in colorectal cancer chemotherapy. | Anticancer research 20120801 |
| Pharmacogenomic applications in oncology. | Journal of pharmacy practice 20120801 |
| DNA topoisomerase I drugs and radiotherapy for lung cancer. | Journal of thoracic disease 20120801 |
| Polymorphisms of UGT1A1*6, UGT1A1*27 & UGT1A1*28 in three major ethnic groups from Malaysia. | The Indian journal of medical research 20120801 |
| Uracil-tegafur/leucovorin and mitomycin C salvage therapy in patients with advanced colorectal cancer: a phase II study. | Journal of chemotherapy (Florence, Italy) 20120801 |
| The efficacy and toxicity of irinotecan with leucovorin and bolus and continuous infusional 5-fluorouracil (FOLFIRI) as salvage therapy for patients with advanced gastric cancer previously treated with platinum and taxane-based chemotherapy regimens. | Journal of chemotherapy (Florence, Italy) 20120801 |
| Docetaxel combined with irinotecan or 5-fluorouracil in patients with advanced oesophago-gastric cancer: a randomised phase II study. | British journal of cancer 20120724 |
| Cost-effectiveness of KRAS testing in metastatic colorectal cancer patients in the United States and Germany. | International journal of cancer 20120715 |
| Phase 2 trial of irinotecan and thalidomide in adults with recurrent anaplastic glioma. | Cancer 20120715 |
| Bevacizumab and irinotecan in children with recurrent or refractory brain tumors: toxicity and efficacy trends. | Pediatric blood & cancer 20120715 |
| Identification of predictive circulating biomarkers of bevacizumab-containing regimen efficacy in pre-treated metastatic colorectal cancer patients. | British journal of cancer 20120710 |
| In vitro and in vivo antitumor activity of cetuximab in human gastric cancer cell lines in relation to epidermal growth factor receptor (EGFR) expression and mutational phenotype. | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20120701 |
| Preclinical study of the cyclodextrin-polymer conjugate of camptothecin CRLX101 for the treatment of gastric cancer. | Nanomedicine : nanotechnology, biology, and medicine 20120701 |
| Analysis of HER-3, insulin growth factor-1, nuclear factor-kB and epidermal growth factor receptor gene copy number in the prediction of clinical outcome for K-RAS wild-type colorectal cancer patients receiving irinotecan-cetuximab. | Annals of oncology : official journal of the European Society for Medical Oncology 20120701 |
| Response prediction in metastasised colorectal cancer using intratumoural thymidylate synthase: results of a randomised multicentre trial. | European journal of cancer (Oxford, England : 1990) 20120701 |
| FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer-subgroup analysis of patients with KRAS: mutated tumours in the randomised German AIO study KRK-0306. | Annals of oncology : official journal of the European Society for Medical Oncology 20120701 |
| Enhanced intracellular accumulation of a non-nucleoside anti-cancer agent via increased uptake of its valine ester prodrug through amino acid transporters. | Xenobiotica; the fate of foreign compounds in biological systems 20120701 |
| Phase II study of irinotecan and amrubicin in patients with relapsed non-small cell lung cancer: Okayama Lung Cancer Study Group Trial 0402. | Acta oncologica (Stockholm, Sweden) 20120701 |
| Utilizing inherent fluorescence of therapeutics to analyze real-time uptake and multi-parametric effector kinetics. | Methods (San Diego, Calif.) 20120701 |
| Liver injury due to chemotherapy-induced sinusoidal obstruction syndrome is associated with sinusoidal capillarization. | Annals of surgical oncology 20120701 |
| Bevacizumab is an active agent for recurrent high-grade glioma, but do we need randomized controlled trials? | Anti-cancer drugs 20120701 |
| Cetuximab-based or bevacizumab-based first-line treatment in patients with KRAS p.G13D-mutated metastatic colorectal cancer: a pooled analysis. | Anti-cancer drugs 20120701 |
| Effects of sequential chemotherapy of FOLFIRI/FOLFOX on the endocrine axes of ACTH-cortisol and renin-angiotensin-aldosterone. | Journal of neuro-oncology 20120701 |
| Simultaneous absolute protein quantification of carboxylesterases 1 and 2 in human liver tissue fractions using liquid chromatography-tandem mass spectrometry. | Drug metabolism and disposition: the biological fate of chemicals 20120701 |
| A phase II trial with bevacizumab and irinotecan for patients with primary brain tumors and progression after standard therapy. | Acta oncologica (Stockholm, Sweden) 20120701 |
| A new UPLC-MS/MS method for the determination of irinotecan and 7-ethyl-10-hydroxycamptothecin (SN-38) in mice: application to plasma and brain pharmacokinetics. | Journal of pharmaceutical and biomedical analysis 20120701 |
| Phase II and gene expression analysis trial of neoadjuvant capecitabine plus irinotecan followed by capecitabine-based chemoradiotherapy for locally advanced rectal cancer: Hoosier Oncology Group GI03-53. | Cancer chemotherapy and pharmacology 20120701 |
| Area under the curve calculation of nedaplatin dose used in combination chemotherapy with irinotecan in a phase I study of gynecologic malignancies. | Cancer chemotherapy and pharmacology 20120701 |
| Bevacizumab plus irinotecan in recurrent malignant glioma shows high overall survival in a multicenter retrospective pooled series of the Spanish Neuro-Oncology Research Group (GEINO). | Anti-cancer drugs 20120701 |
| Fertility-sparing management for bulky cervical cancer using neoadjuvant transuterine arterial chemotherapy followed by vaginal trachelectomy. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20120701 |
| Transarterial chemoembolization with drug-eluting beads preloaded with irinotecan as a first-line approach in uveal melanoma liver metastases: tumor response and predictive value of diffusion-weighted MR imaging in five patients. | Journal of vascular and interventional radiology : JVIR 20120701 |
| Combination of gastrin-releasing peptide antagonist with cytotoxic agents produces synergistic inhibition of growth of human experimental colon cancers. | Cell cycle (Georgetown, Tex.) 20120701 |
| [A case of gastric cancer with peritoneal dissemination who achieved long survival from control of ascites for over 2 years by successive treatments with S-1 in combination with docetaxel as first-line followed by irinotecan in combination with cisplatin as second-line]. | Gan to kagaku ryoho. Cancer & chemotherapy 20120701 |
| Characterization of biological responses of colorectal cancer cells to anticancer regimens. | Journal of the Korean Surgical Society 20120701 |
| Systemic therapy of advanced pancreatic cancer: has the landscape changed? | Clinical advances in hematology & oncology : H&O 20120701 |
| Pharmacogenetic markers of toxicity for chemotherapy in colorectal cancer patients. | Pharmacogenomics 20120701 |
| Comparative and cost-effectiveness of oxaliplatin-based or irinotecan-based regimens compared with 5-fluorouracil/leucovorin alone among US elderly stage IV colon cancer patients. | Cancer 20120615 |
| Discovery of checkpoint kinase inhibitor (S)-5-(3-fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide (AZD7762) by structure-based design and optimization of thiophenecarboxamide ureas. | Journal of medicinal chemistry 20120614 |
| Therapeutic efficacy of a lipid-based prodrug of mitomycin C in pegylated liposomes: studies with human gastro-entero-pancreatic ectopic tumor models. | Journal of controlled release : official journal of the Controlled Release Society 20120610 |
| Irinotecan and DNA-PKcs inhibitors synergize in killing of colon cancer cells. | Investigational new drugs 20120601 |
| DNA interstrand cross-linking and in vivo antitumor activity of the extended pyrrolo[2,1-c][1,4]benzodiazepine dimer SG2057. | Investigational new drugs 20120601 |
| The fate of camptothecin glycoconjugate: report of a clinical hold during a phase II study of BAY 56-3722 (formerly BAY 38-3441), in patients with recurrent or metastatic colorectal cancer resistant/refractory to irinotecan. | Investigational new drugs 20120601 |
| Dasatinib in previously treated metastatic colorectal cancer: a phase II trial of the University of Chicago Phase II Consortium. | Investigational new drugs 20120601 |
| Phase 2 trial of induction and concurrent chemoradiotherapy with weekly irinotecan and cisplatin followed by surgery for esophageal cancer. | Cancer 20120601 |
| Phase III trial of cetuximab, bevacizumab, and 5-fluorouracil/leucovorin vs. FOLFOX-bevacizumab in colorectal cancer. | Clinical colorectal cancer 20120601 |
| Global and local molecular dynamics of a bacterial carboxylesterase provide insight into its catalytic mechanism. | Journal of molecular modeling 20120601 |
| The predictive value of single nucleotide polymorphisms in the VEGF system to the efficacy of first-line treatment with bevacizumab plus chemotherapy in patients with metastatic colorectal cancer: results from the Nordic ACT trial. | International journal of colorectal disease 20120601 |
| Effectiveness of liver metastasectomies in patients with metastatic colorectal cancer treated with FIr-B/FOx triplet chemotherapy plus bevacizumab. | Clinical colorectal cancer 20120601 |
| Gilbert syndrome redefined: a complex genetic haplotype influences the regulation of glucuronidation. | Hepatology (Baltimore, Md.) 20120601 |
| An ectopic ACTH-producing small cell lung carcinoma associated with enhanced corticosteroid biosynthesis in the peritumoral areas of adrenal metastasis. | Lung cancer (Amsterdam, Netherlands) 20120601 |
| Herb-drug interactions and mechanistic and clinical considerations. | Current drug metabolism 20120601 |
| Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab. | Angiogenesis 20120601 |
| Clinical, pharmacokinetic and pharmacodynamic evaluations of metronomic UFT and cyclophosphamide plus celecoxib in patients with advanced refractory gastrointestinal cancers. | Angiogenesis 20120601 |
| TH-302, a hypoxia-activated prodrug with broad in vivo preclinical combination therapy efficacy: optimization of dosing regimens and schedules. | Cancer chemotherapy and pharmacology 20120601 |
| Phase I trial of irinotecan and amrubicin with granulocyte colony-stimulating factor support in extensive-stage small-cell lung cancer. | Cancer chemotherapy and pharmacology 20120601 |
| The PI3K/Akt inhibitor LY294002 reverses BCRP-mediated drug resistance without affecting BCRP translocation. | Oncology reports 20120601 |
| Conventional chemotherapy of advanced pancreatic cancer. | Current drug targets 20120601 |
| MRI-monitored long-term therapeutic hydrogel system for brain tumors without surgical resection. | Biomaterials 20120601 |
| ALDH+ tumor-initiating cells exhibiting gain in NOTCH1 gene copy number have enhanced regrowth sensitivity to a γ-secretase inhibitor and irinotecan in colorectal cancer. | Molecular oncology 20120601 |
| The value of genetic polymorphisms to predict toxicity in metastatic colorectal patients with irinotecan-based regimens. | Cancer chemotherapy and pharmacology 20120601 |
| Selective PI3K inhibition by BKM120 and BEZ235 alone or in combination with chemotherapy in wild-type and mutated human gastrointestinal cancer cell lines. | Cancer chemotherapy and pharmacology 20120601 |
| FOLFIRI as second-line chemotherapy for advanced pancreatic cancer: a GISCAD multicenter phase II study. | Cancer chemotherapy and pharmacology 20120601 |
| Immune-modulating effects of the newest cetuximab-based chemoimmunotherapy regimen in advanced colorectal cancer patients. | Journal of immunotherapy (Hagerstown, Md. : 1997) 20120601 |
| Can immunohistochemistry of multidrug-resistant proteins replace the histoculture drug response assay in colorectal adenocarcinomas? | Hepato-gastroenterology 20120601 |
| High let-7a microRNA levels in KRAS-mutated colorectal carcinomas may rescue anti-EGFR therapy effects in patients with chemotherapy-refractory metastatic disease. | The oncologist 20120601 |
| An update on the ability of St. John's wort to affect the metabolism of other drugs. | Expert opinion on drug metabolism & toxicology 20120601 |
| Clinical and cost effectiveness of bevacizumab + FOLFIRI combination versus FOLFIRI alone as first-line treatment of metastatic colorectal cancer in South Korea. | Clinical therapeutics 20120601 |
| Impact of the UGT1A1*28 allele on response to irinotecan: a systematic review and meta-analysis. | Pharmacogenomics 20120601 |
| Bax expression is predictive of favorable clinical outcome in chemonaive advanced gastric cancer patients treated with capecitabine, oxaliplatin, and irinotecan regimen. | Translational oncology 20120601 |
| Pharmacologic modulation strategies to reduce dose requirements of anticancer therapy while preserving clinical efficacy. | Future oncology (London, England) 20120601 |
| Hepatic arterial infusion in colorectal carcinoma: is anatomical targeting still relevant in an era of molecularly targeted therapy? | Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20120601 |
| The role of capecitabine in locally advanced rectal cancer treatment: an update. | Drugs 20120528 |
| SN-38 loaded polymeric micelles to enhance cancer therapy. | Nanotechnology 20120525 |
| Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. | Journal of medicinal chemistry 20120524 |
| Gender influences the class III and V β-tubulin ability to predict poor outcome in colorectal cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120515 |
| Phase II and UGT1A1 genotype study of irinotecan dose escalation as salvage therapy for advanced gastric cancer. | British journal of cancer 20120508 |
| An EZH2 polymorphism is associated with clinical outcome in metastatic colorectal cancer patients. | Annals of oncology : official journal of the European Society for Medical Oncology 20120501 |
| Outcome of microscopic incomplete resection (R1) of colorectal liver metastases in the era of neoadjuvant chemotherapy. | Annals of surgical oncology 20120501 |
| Peri-operative chemotherapy for resectable colorectal liver metastasis: does timing of systemic therapy matter? | Journal of surgical oncology 20120501 |
| Calpain 2-dependent IκBα degradation mediates CPT-11 secondary resistance in colorectal cancer xenografts. | The Journal of pathology 20120501 |
| Whole abdominopelvic intensity-modulated radiation therapy for desmoplastic small round cell tumor after surgery. | International journal of radiation oncology, biology, physics 20120501 |
| Recent advances in the molecular understanding of glioblastoma. | Journal of neuro-oncology 20120501 |
| Conclusive identification of the oxybutynin-hydrolyzing enzyme in human liver. | Drug metabolism and disposition: the biological fate of chemicals 20120501 |
| CIP2A is a predictor of poor prognosis in colon cancer. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20120501 |
| Clinical development of new formulations of cytotoxics in solid tumors. | Current opinion in oncology 20120501 |
| A phase II study of capecitabine, irinotecan, and bevacizumab in patients with previously untreated metastatic colorectal cancer. | Cancer chemotherapy and pharmacology 20120501 |
| Therapeutic potential and molecular mechanism of a novel sulfonamide anticancer drug, indisulam (E7070) in combination with CPT-11 for cancer treatment. | Cancer chemotherapy and pharmacology 20120501 |
| FDG-PET predicts survival in recurrent high-grade gliomas treated with bevacizumab and irinotecan. | Neuro-oncology 20120501 |
| Pharmacokinetics and antitumor efficacy of XMT-1001, a novel, polymeric topoisomerase I inhibitor, in mice bearing HT-29 human colon carcinoma xenografts. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120501 |
| Adjuvant chemotherapy for stage I clear cell carcinoma of the ovary: an analysis of fully staged patients. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20120501 |
| Salvage chemotherapy for pretreated gastric cancer: a randomized phase III trial comparing chemotherapy plus best supportive care with best supportive care alone. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120501 |
| Modulation of irinotecan-induced genomic DNA damage by theanine. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120501 |
| Phase I study of vincristine, irinotecan, and ¹³¹I-metaiodobenzylguanidine for patients with relapsed or refractory neuroblastoma: a new approaches to neuroblastoma therapy trial. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120501 |
| A weekly combination of carboplatin and irinotecan for previously untreated extensive disease small-cell lung cancer, results of a minimum follow-up of 3 years: a multi-center Phase II trial JMTO LC02-02. | Japanese journal of clinical oncology 20120501 |
| Caspase-mediated pro-apoptotic interaction of panaxadiol and irinotecan in human colorectal cancer cells. | The Journal of pharmacy and pharmacology 20120501 |
| Cetuximab plus cisplatin, irinotecan, and thoracic radiotherapy as definitive treatment for locally advanced, unresectable esophageal cancer: a phase-II study of the SWOG (S0414). | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20120501 |
| Multifactorial pharmacogenetic analysis in colorectal cancer patients receiving 5-fluorouracil-based therapy together with cetuximab-irinotecan. | British journal of clinical pharmacology 20120501 |
| Detailed liver-specific imaging prior to pre-operative chemotherapy for colorectal liver metastases reduces intra-hepatic recurrence and the need for a repeat hepatectomy. | HPB : the official journal of the International Hepato Pancreato Biliary Association 20120501 |
| Response assessment in recurrent glioblastoma treated with irinotecan-bevacizumab: comparative analysis of the Macdonald, RECIST, RANO, and RECIST + F criteria. | Neuro-oncology 20120501 |
| [Monitoring and evaluation tools for irinotecan and bevacizumab in glioblastoma: from prescription to patient's information]. | Bulletin du cancer 20120501 |
| Decreased translation of p21waf1 mRNA causes attenuated p53 signaling in some p53 wild-type tumors. | Cell cycle (Georgetown, Tex.) 20120501 |
| Multidisciplinary treatment of patients with rectal cancer: Development during the past decades and plans for the future. | Upsala journal of medical sciences 20120501 |
| [A case of an advanced gastric cancer patient on hemodialysis achieving long-term progression-free survival after CPT-11+CDDP therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20120501 |
| [A case of remnant liver metastases after resection of liver metastases from rectal cancer following treatment with 5-FU, L-OHP and CPT-11, with markedly effective treatment by cetuximab plus S-1]. | Gan to kagaku ryoho. Cancer & chemotherapy 20120501 |
| [Two cases of CPT-11 and CDDP chemotherapy for advanced pancreatic cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20120501 |
| Cetuximab in metastatic colorectal cancer. | Expert review of anticancer therapy 20120501 |
| A chemical screen identifies the chemotherapeutic drug topotecan as a specific inhibitor of the B-MYB/MYCN axis in neuroblastoma. | Oncotarget 20120501 |
| Infused chemotherapy use in the elderly after patent expiration. | The American journal of managed care 20120501 |
| Uptake of oxaliplatin and bevacizumab for treatment of node-positive and metastatic colon cancer. | Journal of oncology practice 20120501 |
| Infused chemotherapy use in the elderly after patent expiration. | Journal of oncology practice 20120501 |
| Combinational therapy: new hope for pancreatic cancer? | Cancer letters 20120428 |
| Mapping of the UGT1A locus identifies an uncommon coding variant that affects mRNA expression and protects from bladder cancer. | Human molecular genetics 20120415 |
| Discovery of highly potent and selective pan-Aurora kinase inhibitors with enhanced in vivo antitumor therapeutic index. | Journal of medicinal chemistry 20120412 |
| Ovarian small cell carcinoma complicated by carcinomatous meningitis. | Rare tumors 20120412 |
| Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models. | The Journal of clinical investigation 20120402 |
| A phase II study of cell cycle inhibitor UCN-01 in patients with metastatic melanoma: a California Cancer Consortium trial. | Investigational new drugs 20120401 |
| Bevacizumab plus FOLFIRI-3 in chemotherapy-refractory patients with metastatic colorectal cancer in the era of biotherapies. | Investigational new drugs 20120401 |
| Three-gene predictor of clinical outcome for gastric cancer patients treated with chemotherapy. | The pharmacogenomics journal 20120401 |
| Phase II study of combination chemotherapy with biweekly cetuximab and irinotecan for wild-type KRAS metastatic colorectal cancer refractory to irinotecan, oxaliplatin, and fluoropyrimidines. | Investigational new drugs 20120401 |
| Irinotecan injures tight junction and causes bacterial translocation in rat. | The Journal of surgical research 20120401 |
| A Phase Ib pharmacokinetic study of the anti-angiogenic agent CKD-732 used in combination with capecitabine and oxaliplatin (XELOX) in metastatic colorectal cancer patients who progressed on irinotecan-based chemotherapy. | Investigational new drugs 20120401 |
| A change in the apparent diffusion coefficient after treatment with bevacizumab is associated with decreased survival in patients with recurrent glioblastoma multiforme. | The British journal of radiology 20120401 |
| Cetuximab ± chemotherapy enhances dendritic cell-mediated phagocytosis of colon cancer cells and ignites a highly efficient colon cancer antigen-specific cytotoxic T-cell response in vitro. | International journal of cancer 20120401 |
| Phase I study of irinotecan by 24-h intravenous infusion in combination with 5-fluorouracil in metastatic colorectal cancer. | International journal of clinical oncology 20120401 |
| Clinical value of circulating endothelial cell levels in metastatic colorectal cancer patients treated with first-line chemotherapy and bevacizumab. | Annals of oncology : official journal of the European Society for Medical Oncology 20120401 |
| The initial change in tumor size predicts response and survival in patients with metastatic colorectal cancer treated with combination chemotherapy. | Annals of oncology : official journal of the European Society for Medical Oncology 20120401 |
| In vitro antifungal activity of DNA topoisomerase inhibitors. | Medical mycology 20120401 |
| Chemotherapy between the first and second stages of a two-stage hepatectomy for colorectal liver metastases: should we routinely recommend it? | Annals of surgical oncology 20120401 |
| Salvage gamma knife stereotactic radiosurgery followed by bevacizumab for recurrent glioblastoma multiforme: a case-control study. | Journal of neuro-oncology 20120401 |
| UGT1A1 is a major locus influencing bilirubin levels in African Americans. | European journal of human genetics : EJHG 20120401 |
| Involvement of nitric oxide on the pathogenesis of irinotecan-induced intestinal mucositis: role of cytokines on inducible nitric oxide synthase activation. | Cancer chemotherapy and pharmacology 20120401 |
| Regulator of G-protein signaling 5 (RGS5) protein: a novel marker of cancer vasculature elicited and sustained by the tumor's proangiogenic microenvironment. | Cellular and molecular life sciences : CMLS 20120401 |
| How informative is a negative finding in a small pharmacogenetic study? | The pharmacogenomics journal 20120401 |
| Bacterial immunotherapy of gastrointestinal tumors. | Langenbeck's archives of surgery 20120401 |
| Human organic cation transporter 1 is expressed in lymphoma cells and increases susceptibility to irinotecan and paclitaxel. | The Journal of pharmacology and experimental therapeutics 20120401 |
| Continuous inhibition of epidermal growth factor receptor phosphorylation by erlotinib enhances antitumor activity of chemotherapy in erlotinib-resistant tumor xenografts. | Oncology reports 20120401 |
| Ovarian VEGF(165)b expression regulates follicular development, corpus luteum function and fertility. | Reproduction (Cambridge, England) 20120401 |
| Ugt1a is required for the protective effect of selenium against irinotecan-induced toxicity. | Cancer chemotherapy and pharmacology 20120401 |
| Development of a combination drug-eluting bead: towards enhanced efficacy for locoregional tumour therapies. | Anti-cancer drugs 20120401 |
| Demethylation restores SN38 sensitivity in cells with acquired resistance to SN38 derived from human cervical squamous cancer cells. | Oncology reports 20120401 |
| Intraoperative detection of disappearing colorectal liver metastases as a predictor of residual disease. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20120401 |
| Treatment of unresectable cholangiocarcinoma: conventional transarterial chemoembolization compared with drug eluting bead-transarterial chemoembolization and systemic chemotherapy. | European journal of gastroenterology & hepatology 20120401 |
| NMS-P937, an orally available, specific small-molecule polo-like kinase 1 inhibitor with antitumor activity in solid and hematologic malignancies. | Molecular cancer therapeutics 20120401 |
| Germline pharmacogenomics in oncology: decoding the patient for targeting therapy. | Molecular oncology 20120401 |
| A Japanese post-marketing surveillance of cetuximab (Erbitux®) in patients with metastatic colorectal cancer. | Japanese journal of clinical oncology 20120401 |
| A multicenter, multinational analysis of mitomycin C in refractory metastatic colorectal cancer. | European journal of cancer (Oxford, England : 1990) 20120401 |
| HER2 as therapeutic target for overcoming ATP-binding cassette transporter-mediated chemoresistance in small cell lung cancer. | Molecular cancer therapeutics 20120401 |
| First-line treatment with capecitabine combined with irinotecan in patients with advanced colorectal carcinoma: a phase II study. | Journal of clinical gastroenterology 20120401 |
| Alternative chemotherapeutic agents: nitrosoureas, cisplatin, irinotecan. | Neurosurgery clinics of North America 20120401 |
| Single-photon emission computed tomographic imaging of the early time course of therapy-induced cell death using technetium 99m tricarbonyl His-annexin A5 in a colorectal cancer xenograft model. | Molecular imaging 20120401 |
| [Successful management of liver metastasis from gastric adenosquamous carcinoma with adjuvant chemotherapy and radiofrequency ablation]. | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20120401 |
| Intra-arterial infusion of irinotecan-loaded drug-eluting beads (DEBIRI) versus intravenous therapy (FOLFIRI) for hepatic metastases from colorectal cancer: final results of a phase III study. | Anticancer research 20120401 |
| Nedaplatin and irinotecan in patients with large-cell neuroendocrine carcinoma of the lung. | Anticancer research 20120401 |
| Colorectal cancer and thoracic surgeons: close encounters of the third kind. | Expert review of anticancer therapy 20120401 |
| Wig-1, a novel regulator of N-Myc mRNA and N-Myc-driven tumor growth. | Cell death & disease 20120401 |
| Kinase inhibitors for advanced medullary thyroid carcinoma. | Clinics (Sao Paulo, Brazil) 20120401 |
| Repeated transarterial chemoembolisation using different chemotherapeutic drug combinations followed by MR-guided laser-induced thermotherapy in patients with liver metastases of colorectal carcinoma. | British journal of cancer 20120327 |
| A cell-delivered and cell-activated SN38-dextran prodrug increases survival in a murine disseminated pancreatic cancer model. | Small (Weinheim an der Bergstrasse, Germany) 20120326 |
| Quantification of irinotecan, SN38, and SN38G in human and porcine plasma by ultra high-performance liquid chromatography-tandem mass spectrometry and its application to hepatic chemoembolization. | Journal of pharmaceutical and biomedical analysis 20120325 |
| Radiation Therapy Oncology Group 0247: a randomized Phase II study of neoadjuvant capecitabine and irinotecan or capecitabine and oxaliplatin with concurrent radiotherapy for patients with locally advanced rectal cancer. | International journal of radiation oncology, biology, physics 20120315 |
| Postoperative adjuvant chemotherapy in rectal cancer operated for cure. | The Cochrane database of systematic reviews 20120314 |
| Microsatellite instability and Beta2-Microglobulin mutations as prognostic markers in colon cancer: results of the FOGT-4 trial. | British journal of cancer 20120313 |
| Locally advanced pancreatic adenocarcinoma: update and progress. | JOP : Journal of the pancreas 20120310 |
| What options are available for refractory pancreatic cancer? | JOP : Journal of the pancreas 20120310 |
| Irinotecan plus cisplatin chemotherapy followed by concurrent thoracic irradiation with low-dose weekly cisplatin for limited-disease small-cell lung cancer. | Medical oncology (Northwood, London, England) 20120301 |
| Dose escalation of intravenous irinotecan using oral cefpodoxime: a phase I study in pediatric patients with refractory solid tumors. | Pediatric blood & cancer 20120301 |
| Wipe sampling procedure coupled to LC-MS/MS analysis for the simultaneous determination of 10 cytotoxic drugs on different surfaces. | Analytical and bioanalytical chemistry 20120301 |
| Bevacizumab and daily temozolomide for recurrent glioblastoma. | Cancer 20120301 |
| Bevacizumab combined with chemotherapy in the second-line treatment of metastatic colorectal cancer: results from the phase II BEVACOLOR study. | Clinical colorectal cancer 20120301 |
| Phase II study of irinotecan and cetuximab given every 2 weeks as second-line therapy for advanced colorectal cancer. | Clinical colorectal cancer 20120301 |
| Outcome of second-line treatment after first-line chemotherapy with the GONO FOLFOXIRI regimen. | Clinical colorectal cancer 20120301 |
| Evaluation of a formula for individual dosage of nedaplatin based on renal function. | Cancer chemotherapy and pharmacology 20120301 |
| Panitumumab in combination with cytotoxic chemotherapy for the treatment of metastatic colorectal carcinoma. | Clinical colorectal cancer 20120301 |
| Phase II study of carboplatin, irinotecan, and bevacizumab for bevacizumab naïve, recurrent glioblastoma. | Journal of neuro-oncology 20120301 |
| The effect of postoperative pelvic irradiation after complete resection of metastatic rectal cancer. | Journal of surgical oncology 20120301 |
| A phase I dose-escalation and pharmacokinetic study of sunitinib in combination with pemetrexed in patients with advanced solid malignancies, with an expanded cohort in non-small cell lung cancer. | Cancer chemotherapy and pharmacology 20120301 |
| Feasibility of biweekly combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in patients with metastatic solid tumors: results of a two-step phase I trial: XELIRI and XELIRINOX. | Cancer chemotherapy and pharmacology 20120301 |
| Predictive biomarkers with potential of converting conventional chemotherapy to targeted therapy in patients with metastatic colorectal cancer. | Scandinavian journal of gastroenterology 20120301 |
| Pharmacogenomics and metastatic colorectal cancer: current knowledge and perspectives. | Scandinavian journal of gastroenterology 20120301 |
| Reliability of tumor primary cultures as a model for drug response prediction: expression profiles comparison of tissues versus primary cultures from colorectal cancer patients. | Journal of cancer research and clinical oncology 20120301 |
| Simultaneous surgery for primary colorectal cancer and metastatic lesions? | Scandinavian journal of gastroenterology 20120301 |
| Phase II study of biweekly cetuximab in combination with irinotecan as second-line treatment in patients with platinum-resistant gastro-oesophageal cancer. | European journal of cancer (Oxford, England : 1990) 20120301 |
| The economic pressures for biosimilar drug use in cancer medicine. | Targeted oncology 20120301 |
| Disruption of the murine Glp2r impairs Paneth cell function and increases susceptibility to small bowel enteritis. | Endocrinology 20120301 |
| Hypoxia-inducible factor-1α and excision repair cross-complementing 1 in patients with small cell lung cancer who received front-line platinum-based chemotherapy: a retrospective study. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20120301 |
| Delivery methods of camptothecin and its hydrosoluble analogue irinotecan for treatment of colorectal cancer. | Current drug delivery 20120301 |
| Treatment outcome of patients with anaplastic thyroid cancer: a single center experience. | Yonsei medical journal 20120301 |
| Phase II study of oral etoposide and intravenous irinotecan for patients with platinum-resistant and taxane-pretreated ovarian cancer: Japan Clinical Oncology Group Study 0503. | Japanese journal of clinical oncology 20120301 |
| Absence of transcriptomic signature of response to chemotherapy in metastatic colorectal carcinoma patients. | Pharmacogenomics 20120301 |
| Phase 2 study of modified irinotecan and bolus 5-fluorouracil/l-leucovorin in Japanese metastatic colorectal cancer patients. | Advances in therapy 20120301 |
| SN-38 overcomes chemoresistance of colorectal cancer cells induced by hypoxia, through HIF1alpha. | Anticancer research 20120301 |
| [A case of S-1-resistant resected advanced gastric cancer with para-aortic lymph node recurrence responding to bi-weekly CPT-11 and CDDP]. | Gan to kagaku ryoho. Cancer & chemotherapy 20120301 |
| Therapeutic strategy in unresectable metastatic colorectal cancer. | Therapeutic advances in medical oncology 20120301 |
| Asymptomatic pneumatosis intestinalis following chemotherapy for B lymphoblastic leukemia with recurrent genetic abnormalities in an adolescent patient. | The Korean journal of hematology 20120301 |
| Chemotherapy in Patients Older than or Equal to 75 Years with Advanced Non-small Cell Lung Cancer. | Cancer research and treatment : official journal of Korean Cancer Association 20120301 |
| A phase II randomized study of combined infusional leucovorin sodium and 5- FU versus the leucovorin calcium followed by 5-FU both in combination with irinotecan or oxaliplatin in patients with metastatic colorectal cancer. | Acta gastro-enterologica Belgica 20120301 |
| Irinophore C™, a lipid-based nanoparticulate formulation of irinotecan, is more effective than free irinotecan when used to treat an orthotopic glioblastoma model. | Journal of controlled release : official journal of the Controlled Release Society 20120227 |
| Immunohistochemical discrimination of wild-type EGFR from EGFRvIII in fixed tumour specimens using anti-EGFR mAbs ICR9 and ICR10. | British journal of cancer 20120227 |
| Effectiveness of bevacizumab with first-line combination chemotherapy for Medicare patients with stage IV colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120220 |
| Quantitative cell-free DNA, KRAS, and BRAF mutations in plasma from patients with metastatic colorectal cancer during treatment with cetuximab and irinotecan. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120215 |
| RAFT-derived polymer-drug conjugates: poly(hydroxypropyl methacrylamide) (HPMA)-7-ethyl-10-hydroxycamptothecin (SN-38) conjugates. | ChemMedChem 20120206 |
| The transport of nifurtimox, an anti-trypanosomal drug, in an in vitro model of the human blood-brain barrier: evidence for involvement of breast cancer resistance protein. | Brain research 20120203 |
| Effect of ketoconazole on the pharmacokinetics of axitinib in healthy volunteers. | Investigational new drugs 20120201 |
| Combined treatment with bevacizumab and standard chemotherapy restores abnormal immune parameters in advanced colorectal cancer patients. | Investigational new drugs 20120201 |
| Phase I study of oral irinotecan as a single-agent and given sequentially with capecitabine. | Investigational new drugs 20120201 |
| Stage-to-stage comparison of preoperative and postoperative chemoradiotherapy for T3 mid or distal rectal cancer. | International journal of radiation oncology, biology, physics 20120201 |
| Successful treatment of an intra-abdominal desmoid tumor with irinotecan, fluorouracil, and leucovorin plus bevacizumab in a patient with familial adenomatous polyposis. | International journal of colorectal disease 20120201 |
| In vitro cytotoxic effect of ethanol extract prepared from sporophyll of Undaria pinnatifida on human colorectal cancer cells. | Phytotherapy research : PTR 20120201 |
| Tumor volume reduction rate after preoperative chemoradiotherapy as a prognostic factor in locally advanced rectal cancer. | International journal of radiation oncology, biology, physics 20120201 |
| A multicenter analysis of GTX chemotherapy in patients with locally advanced and metastatic pancreatic adenocarcinoma. | Cancer chemotherapy and pharmacology 20120201 |
| Outcome and natural history of patients with stage IV colorectal cancer receiving chemotherapy without primary tumor resection. | Annals of surgical oncology 20120201 |
| Use of S-100B to evaluate therapy effects during bevacizumab induction treatment in AJCC stage III melanoma. | Annals of surgical oncology 20120201 |
| Inhibition of Cathepsin S by Fsn0503 enhances the efficacy of chemotherapy in colorectal carcinomas. | Biochimie 20120201 |
| Capecitabine and bevacizumab in heavily pre-treated patients with advanced colorectal cancer. | Acta oncologica (Stockholm, Sweden) 20120201 |
| Apoptosis sensitizers enhance cytotoxicity in hepatoblastoma cells. | Pediatric surgery international 20120201 |
| Dual functional octreotide-modified liposomal irinotecan leads to high therapeutic efficacy for medullary thyroid carcinoma xenografts. | Cancer science 20120201 |
| Are KRAS/BRAF mutations potent prognostic and/or predictive biomarkers in colorectal cancers? | Anti-cancer agents in medicinal chemistry 20120201 |
| Practice guidance on the management of acute and chronic gastrointestinal problems arising as a result of treatment for cancer. | Gut 20120201 |
| Human neural stem cell tropism to metastatic breast cancer. | Stem cells (Dayton, Ohio) 20120201 |
| Predictive and prognostic roles of BRAF mutation in stage III colon cancer: results from intergroup trial CALGB 89803. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120201 |
| FOLFIRI plus bevacizumab 5 mg/kg versus 10 mg/kg as second-line therapy in patients with metastatic colorectal cancer who have failed first-line bevacizumab plus oxaliplatin-based therapy: a randomized phase III study (EAGLE Study). | Japanese journal of clinical oncology 20120201 |
| Patterns of treatment with chemotherapy and monoclonal antibodies for metastatic colorectal cancer in Western Europe. | Current medical research and opinion 20120201 |
| Analytical performance of a PCR assay for the detection of KRAS mutations (codons 12/13 and 61) in formalin-fixed paraffin-embedded tissue samples of colorectal carcinoma. | Virchows Archiv : an international journal of pathology 20120201 |
| Antitumor activity of BRAF inhibitor vemurafenib in preclinical models of BRAF-mutant colorectal cancer. | Cancer research 20120201 |
| Sudden death related to toxicity in a patient on capecitabine and irinotecan plus bevacizumab intake: pharmacogenetic implications. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120201 |
| Genomics and pharmacogenomics of pancreatic adenocarcinoma. | The pharmacogenomics journal 20120201 |
| Preclinical development of the novel Chk1 inhibitor SCH900776 in combination with DNA-damaging agents and antimetabolites. | Molecular cancer therapeutics 20120201 |
| Low-dosage metronomic chemotherapy and angiogenesis: topoisomerase inhibitors irinotecan and mitoxantrone stimulate VEGF-A-mediated angiogenesis. | APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20120201 |
| An updated meta-analysis of randomized controlled trials comparing irinotecan/platinum with etoposide/platinum in patients with previously untreated extensive-stage small cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20120201 |
| [Retrospective analysis of 24 recurrent glioblastoma after chemoradiation and treated with nitrosoureas or irinotecan and bevacizumab]. | Bulletin du cancer 20120201 |
| Viewing metastatic colorectal cancer as a curable chronic disease. | American journal of clinical oncology 20120201 |
| [A case of cecal cancer with abdominal wall abscess]. | Gan to kagaku ryoho. Cancer & chemotherapy 20120201 |
| [A case of irinotecan or panitumumab-induced interstitial pneumonia successfully treated by steroid pulse therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20120201 |
| More than 7-year survival of a patient following repeat hepatectomy for total 20 colon cancer liver metastases. | Journal of the Korean Surgical Society 20120201 |
| A race between tumor immunoescape and genome maintenance selects for optimum levels of (epi)genetic instability. | PLoS computational biology 20120201 |
| Large cell neuroendocrine carcinoma of the thymus: a two-case report. | The Korean journal of thoracic and cardiovascular surgery 20120201 |
| Multivariate Analysis of the Survival Rate for Treatment Modalities in Incurable Stage IV Colorectal Cancer. | Journal of the Korean Society of Coloproctology 20120201 |
| Randomised phase-II trial of CAPIRI (capecitabine, irinotecan) plus bevacizumab vs FOLFIRI (folinic acid, 5-fluorouracil, irinotecan) plus bevacizumab as first-line treatment of patients with unresectable/metastatic colorectal cancer (mCRC). | British journal of cancer 20120131 |
| Treatment of colorectal peritoneal carcinomatosis with systemic chemotherapy: a pooled analysis of north central cancer treatment group phase III trials N9741 and N9841. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120120 |
| Cetuximab-based therapy in elderly comorbid patients with metastatic colorectal cancer. | British journal of cancer 20120117 |
| Comparison of the predictive ability of several second-order multivariate methods in the simultaneous determination of two therapeutic drugs in human urine. | Talanta 20120115 |
| Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons. | Nature 20120112 |
| Total synthesis of camptothecin and SN-38. | The Journal of organic chemistry 20120106 |
| TFAP2E-DKK4 and chemoresistance in colorectal cancer. | The New England journal of medicine 20120105 |
| Adenosine triphosphate-based chemotherapy response assay-guided chemotherapy in unresectable colorectal liver metastasis. | British journal of cancer 20120103 |
| Topoisomerase I inhibition in colorectal cancer: biomarkers and therapeutic targets. | British journal of cancer 20120103 |
| Phase I dose escalation trial of vandetanib with fractionated radiosurgery in patients with recurrent malignant gliomas. | International journal of radiation oncology, biology, physics 20120101 |
| Addition of bevacizumab to standard radiation therapy and daily temozolomide is associated with minimal toxicity in newly diagnosed glioblastoma multiforme. | International journal of radiation oncology, biology, physics 20120101 |
| Review of biomarkers in colorectal cancer. | Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20120101 |
| Chemotherapy-induced nausea and vomiting in daily clinical practice: a community hospital-based study. | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20120101 |
| A self-contained enzyme activating prodrug cytotherapy for preclinical melanoma. | Molecular biology reports 20120101 |
| Combining capecitabine, oxaliplatin, and gemcitabine (XELOXGEM) for colorectal carcinoma patients pretreated with irinotecan: a multicenter phase I/II trial. | Cancer chemotherapy and pharmacology 20120101 |
| Antiangiogenic therapy for patients with recurrent and newly diagnosed malignant gliomas. | Journal of oncology 20120101 |
| Treatment of recurrent diffuse intrinsic pontine glioma: the MD Anderson Cancer Center experience. | Journal of neuro-oncology 20120101 |
| Targeting the tumor microenvironment: focus on angiogenesis. | Journal of oncology 20120101 |
| Identification of a potent epigenetic biomarker for resistance to camptothecin and poor outcome to irinotecan-based chemotherapy in colon cancer. | International journal of oncology 20120101 |
| The Role of PTEN in Tumor Angiogenesis. | Journal of oncology 20120101 |
| Lipoplatin formulation review article. | Journal of drug delivery 20120101 |
| Antitumor activity of IHL-305, a novel pegylated liposome containing irinotecan, in human xenograft models. | Oncology reports 20120101 |
| Natural products from ethnodirected studies: revisiting the ethnobiology of the zombie poison. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| Overexpression of BMI-1 correlates with drug resistance in B-cell lymphoma cells through the stabilization of survivin expression. | Cancer science 20120101 |
| VEGF spliced variants: possible role of anti-angiogenesis therapy. | Journal of nucleic acids 20120101 |
| A systems biology approach identifies SART1 as a novel determinant of both 5-fluorouracil and SN38 drug resistance in colorectal cancer. | Molecular cancer therapeutics 20120101 |
| Phase I trial of vorinostat combined with bevacizumab and CPT-11 in recurrent glioblastoma. | Neuro-oncology 20120101 |
| In vivo topoisomerase I inhibition attenuates the expression of hypoxia-inducible factor 1α target genes and decreases tumor angiogenesis. | Molecular medicine (Cambridge, Mass.) 20120101 |
| Epratuzumab-SN-38: a new antibody-drug conjugate for the therapy of hematologic malignancies. | Molecular cancer therapeutics 20120101 |
| Impact of SHMT1 polymorphism on the clinical outcome of patients with metastatic colorectal cancer treated with first-line FOLFIRI+bevacizumab. | Pharmacogenetics and genomics 20120101 |
| Kampo medicine 'Dai-kenchu-to' prevents CPT-11-induced small-intestinal injury in rats. | Surgery today 20120101 |
| Basal breast cancer: a complex and deadly molecular subtype. | Current molecular medicine 20120101 |
| Epidermal growth factor receptor mutations in small cell lung cancer patients who received surgical resection in China. | Neoplasma 20120101 |
| The central vein access port and catheter in outpatient chemotherapy for colorectal cancer: a retrospective study of 101 patients. | Surgery today 20120101 |
| Synergistic Effect of Geranylgeranyltransferase Inhibitor, GGTI, and Docetaxel on the Growth of Prostate Cancer Cells. | Prostate cancer 20120101 |
| Usefulness of multidisciplinary therapy combining neoadjuvant chemotherapy with S-1 plus cisplatin and postoperative sequential chemotherapy in patients with scirrhous gastric cancer. | Hepato-gastroenterology 20120101 |
| [Treatment of metastatic colorectal cancer: an illustration of the changes in the cancer paradigms]. | Presse medicale (Paris, France : 1983) 20120101 |
| Angiogenesis in head and neck cancer: a review of the literature. | Journal of oncology 20120101 |
| Biological mechanism and clinical effect of protein-bound polysaccharide K (KRESTIN(®)): review of development and future perspectives. | Surgery today 20120101 |
| Oxaliplatin: a review of approved uses. | Expert opinion on pharmacotherapy 20120101 |
| TOP1 gene copy numbers in colorectal cancer samples and cell lines and their association to in vitro drug sensitivity. | Scandinavian journal of gastroenterology 20120101 |
| Pharmacogenetics of drug-metabolizing enzymes: the prodrug hypothesis. | Pharmacogenomics 20120101 |
| Elevated serum C-reactive protein as a prognostic marker in small cell lung cancer. | Yonsei medical journal 20120101 |
| Association of ABCC2 genotype with efficacy of first-line FOLFIRI in Japanese patients with advanced colorectal cancer. | Drug metabolism and pharmacokinetics 20120101 |
| Greco-arab and islamic herbal-derived anticancer modalities: from tradition to molecular mechanisms. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| Panitumumab in patients with KRAS wild-type colorectal cancer after progression on cetuximab. | The oncologist 20120101 |
| Adverse event profiles of 5-fluorouracil and capecitabine: data mining of the public version of the FDA Adverse Event Reporting System, AERS, and reproducibility of clinical observations. | International journal of medical sciences 20120101 |
| Progression-free Survival Decreases with Each Subsequent Therapy in Patients Presenting for Phase I Clinical Trials. | Journal of Cancer 20120101 |
| Trastuzumab has opposing effects on SN-38-induced double-strand breaks and cytotoxicity in HER2-positive gastric cancer cells depending on administration sequence. | Anticancer research 20120101 |
| Risk groups defined by Recursive Partitioning Analysis of patients with colorectal adenocarcinoma treated with colorectal resection. | BMC medical research methodology 20120101 |
| Predictive and prognostic value of circulating nucleosomes and serum biomarkers in patients with metastasized colorectal cancer undergoing Selective Internal Radiation Therapy. | BMC cancer 20120101 |
| Involvement of specific transport system on uptake of lactone form of SN-38 in human intestinal epithelial cell line Caco-2. | Biological & pharmaceutical bulletin 20120101 |
| Effects of bevacizumab on the neovascular membrane of proliferative diabetic retinopathy: reduction of endothelial cells and expressions of VEGF and HIF-1α. | Molecular vision 20120101 |
| Aflibercept in the treatment of metastatic colorectal cancer. | Clinical Medicine Insights. Oncology 20120101 |
| Safety and efficacy of everolimus in adult patients with neuroendocrine tumors. | Clinical Medicine Insights. Oncology 20120101 |
| Prediction of glioblastoma multiform response to bevacizumab treatment using multi-parametric MRI. | PloS one 20120101 |
| Isolation and characterization of a murine P388 leukemia line resistant to thiarabine. | Nucleosides, nucleotides & nucleic acids 20120101 |
| Evaluation of biocompatibility and anti-glioma efficacy of doxorubicin and irinotecan drug-eluting bead suspensions in alginate. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20120101 |
| The cost-effectiveness of different chemotherapy strategies for patients with poor prognosis advanced colorectal cancer (MRC FOCUS). | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20120101 |
| Cucurbitacin E Induces G(2)/M Phase Arrest through STAT3/p53/p21 Signaling and Provokes Apoptosis via Fas/CD95 and Mitochondria-Dependent Pathways in Human Bladder Cancer T24 Cells. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy. | Theranostics 20120101 |
| Anti-tumor effect against human cancer xenografts by a fully human monoclonal antibody to a variant 8-epitope of CD44R1 expressed on cancer stem cells. | PloS one 20120101 |
| Vascular complications and diabetes: current therapies and future challenges. | Journal of ophthalmology 20120101 |
| The effect of intravitreal anti-VEGF agents on peripheral wound healing in a rabbit model. | Clinical ophthalmology (Auckland, N.Z.) 20120101 |
| 5-Fluorouracil-loaded poly(ε-caprolactone) nanoparticles combined with phage E gene therapy as a new strategy against colon cancer. | International journal of nanomedicine 20120101 |
| Autocrine prostaglandin E2 signaling promotes tumor cell survival and proliferation in childhood neuroblastoma. | PloS one 20120101 |
| In vivo expansion of naïve CD4+ CD25(high) FOXP3+ regulatory T cells in patients with colorectal carcinoma after IL-2 administration. | PloS one 20120101 |
| Monoclonal antibodies and Fc fragments for treating solid tumors. | Biologics : targets & therapy 20120101 |
| Drug transporter regulation in tumors by DNA methylation. | Genome medicine 20120101 |
| [Examination of factors affecting adverse reactions and dosage reduction in UGT1A1 genotyped patients: a retrospective survey of irinotecan]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20120101 |
| Molecular basis of triple negative breast cancer and implications for therapy. | International journal of breast cancer 20120101 |
| Metabolic syndrome and triple-negative breast cancer: a new paradigm. | International journal of breast cancer 20120101 |
| Neoplastic cells are a rare component in human glioblastoma microvasculature. | Oncotarget 20120101 |
| Immunohistochemical profile for unknown primary adenocarcinoma. | PloS one 20120101 |
| MiRNAs and LincRNAs: Could they be considered as biomarkers in colorectal cancer? | International journal of molecular sciences 20120101 |
| Increased serum sTRAIL levels were correlated with survival in bevacizumab-treated metastatic colon cancer. | BMC cancer 20120101 |
| Molecular Characterization of a Patient's Small Cell Carcinoma of the Ovary of the Hypercalcemic Type. | Journal of Cancer 20120101 |
| Genetic polymorphisms of FcγRIIa and FcγRIIIa are not predictive of clinical outcomes after cetuximab plus irinotecan chemotherapy in patients with metastatic colorectal cancer. | Oncology 20120101 |
| Therapeutic strategies in epithelial ovarian cancer. | Journal of experimental & clinical cancer research : CR 20120101 |
| Defective cell cycle checkpoints as targets for anti-cancer therapies. | Frontiers in pharmacology 20120101 |
| Cord blood stem cells inhibit epidermal growth factor receptor translocation to mitochondria in glioblastoma. | PloS one 20120101 |
| Effects of α-adrenoceptor antagonists on ABCG2/BCRP-mediated resistance and transport. | PloS one 20120101 |
| Identification of links between small molecules and miRNAs in human cancers based on transcriptional responses. | Scientific reports 20120101 |
| Prostatic metastasis of pulmonary large cell neuroendocrine carcinoma. | Journal of Cancer 20120101 |
| ER stress negatively modulates the expression of the miR-199a/214 cluster to regulates tumor survival and progression in human hepatocellular cancer. | PloS one 20120101 |
| Anti-malarial activity of geldanamycin derivatives in mice infected with Plasmodium yoelii. | Malaria journal 20120101 |
| Signaling networks associated with AKT activation in non-small cell lung cancer (NSCLC): new insights on the role of phosphatydil-inositol-3 kinase. | PloS one 20120101 |
| DPEP1 inhibits tumor cell invasiveness, enhances chemosensitivity and predicts clinical outcome in pancreatic ductal adenocarcinoma. | PloS one 20120101 |
| A high performance liquid chromatographic assay of mefloquine in saliva after a single oral dose in healthy adult Africans. | Malaria journal 20120101 |
| Untreated celiac disease in a patient with dermatitis herpetiformis leading to a small bowel carcinoma. | Case reports in gastroenterology 20120101 |
| Occult breast cancer presenting as metastatic adenocarcinoma of unknown primary: clinical presentation, immunohistochemistry, and molecular analysis. | Case reports in oncology 20120101 |
| Irinotecan-induced dysarthria. | Case reports in oncology 20120101 |
| Chemotherapeutics and radiation stimulate MHC class I expression through elevated interferon-beta signaling in breast cancer cells. | PloS one 20120101 |
| Systemic delivery of oncolytic viruses: hopes and hurdles. | Advances in virology 20120101 |
| Toxin-based targeted therapy for malignant brain tumors. | Clinical & developmental immunology 20120101 |
| Intra-arterial delivery of bevacizumab after blood-brain barrier disruption for the treatment of recurrent glioblastoma: progression-free survival and overall survival. | World neurosurgery 20120101 |
| Pneumatosis intestinalis and portal venous gas secondary to Gefitinib therapy for lung adenocarcinoma. | BMC cancer 20120101 |
| Long-term treatment of metastatic colorectal cancer with panitumumab. | Clinical Medicine Insights. Oncology 20120101 |
| A novel LMP1 antibody synergizes with mitomycin C to inhibit nasopharyngeal carcinoma growth in vivo through inducing apoptosis and downregulating vascular endothelial growth factor. | International journal of molecular sciences 20120101 |
| Regulation of aldo-keto reductases in human diseases. | Frontiers in pharmacology 20120101 |
| Amphiregulin and Epiregulin mRNA expression in primary colorectal cancer and corresponding liver metastases. | BMC cancer 20120101 |
| Addition of bevacizumab to first-line chemotherapy in advanced colorectal cancer: a systematic review and meta-analysis, with emphasis on chemotherapy subgroups. | BMC cancer 20120101 |
| Advanced gastric neuroendocrine carcinoma with an adenocarcinoma component. | Case reports in gastroenterology 20120101 |
| Adult Intussusception Caused by Descending Colon Cancer during Chemotherapy of Stomach Cancer Recurrence. | Case reports in gastroenterology 20120101 |
| Phase II study of helical tomotherapy in the multidisciplinary treatment of oligometastatic colorectal cancer. | Radiation oncology (London, England) 20120101 |
| Synthetic lethal screen identifies NF-κB as a target for combination therapy with topotecan for patients with neuroblastoma. | BMC cancer 20120101 |
| Is there a role for the quantification of RRM1 and ERCC1 expression in pancreatic ductal adenocarcinoma? | BMC cancer 20120101 |
| Micropapillary lung cancer with breast metastasis simulating primary breast cancer due to architectural distortion on images. | Korean journal of radiology 20120101 |
| Nuclear factor-kappa B inhibition can enhance apoptosis of differentiated thyroid cancer cells induced by 131I. | PloS one 20120101 |
| Retrospective study comparing irinotecan and pegylated liposomal doxorubicin in treatment of recurrent platinum-refractory/resistant epithelial ovarian cancer. | European journal of gynaecological oncology 20120101 |
| A phase II study for metabolic in vivo response monitoring with sequential 18FDG-PET-CT during treatment with the EGFR-monoclonal-antibody cetuximab in metastatic colorectal cancer: the Heidelberg REMOTUX trial. | BMC cancer 20120101 |
| Downregulation of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) in human hepatocellular carcinoma and their prognostic significance. | BMC cancer 20120101 |
| Increased expression of drug-metabolizing enzymes in human hepatocarcinoma FLC-4 cells cultured on micro-space cell culture plates. | Drug metabolism and pharmacokinetics 20120101 |
| Fertility preservation in female cancer patients. | ISRN obstetrics and gynecology 20120101 |
| Irinotecan plus mitomycin C as second-line chemotherapy for advanced gastric cancer resistant to fluoropyrimidine and Cisplatin: a retrospective study. | Gastroenterology research and practice 20120101 |
| Cellular-based immunotherapies for patients with glioblastoma multiforme. | Clinical & developmental immunology 20120101 |
| Resection of the primary tumour versus no resection prior to systemic therapy in patients with colon cancer and synchronous unresectable metastases (UICC stage IV): SYNCHRONOUS--a randomised controlled multicentre trial (ISRCTN30964555). | BMC cancer 20120101 |
| Hepatic arterial therapy with drug-eluting beads in the management of metastatic pancreatic carcinoma to the liver: a multi-institutional registry. | Journal of oncology 20120101 |
| Hepatic arterial therapy with drug-eluting beads in the management of metastatic bronchogenic carcinoma to the liver: a multi-institutional registry. | Journal of oncology 20120101 |
| Special Agents Hunting Down Women Silent Killer: The Emerging Role of the p38α Kinase. | Journal of oncology 20120101 |
| The molecular biology of brain metastasis. | Journal of oncology 20120101 |
| An observational study of the first experience with bevacizumab for the treatment of patients with recurrent high-grade glioma in two belgian university hospitals. | Journal of oncology 20120101 |
| Isolated cardiac metastasis from colorectal cancer in a 35-year-old man. | Case reports in medicine 20120101 |
| Healthcare costs and workloss burden of patients with chemotherapy-associated peripheral neuropathy in breast, ovarian, head and neck, and nonsmall cell lung cancer. | Chemotherapy research and practice 20120101 |
| Increased activity of cell surface peptidases in HeLa cells undergoing UV-induced apoptosis is not mediated by caspase 3. | International journal of molecular sciences 20120101 |
| Phosphorylated AKT and MAPK expression in primary tumours and in corresponding metastases and clinical outcome in colorectal cancer patients receiving irinotecan-cetuximab. | Journal of translational medicine 20120101 |
| Cyclodextrin-containing polymers: versatile platforms of drug delivery materials. | Journal of drug delivery 20120101 |
| Economic comparison of capecitabine + oxaliplatin and 5-fluorouracil + oxaliplatin in the adjuvant treatment of colon cancer. | Cancer management and research 20120101 |
| Tetrathiomolybdate sensitizes ovarian cancer cells to anticancer drugs doxorubicin, fenretinide, 5-fluorouracil and mitomycin C. | BMC cancer 20120101 |
| The developing clinical problem of chemotherapy-induced hepatic injury. | ANZ journal of surgery 20120101 |
| A phase I study of infusional 5-fluorouracil, leucovorin, oxaliplatin and irinotecan in Japanese patients with advanced colorectal cancer who harbor UGT1A1*1/*1,*1/*6 or *1/*28. | Oncology 20120101 |
| [Pneumatosis cystoides intestinalis during palliative chemotherapy for colorectal cancer]. | Revue medicale de Bruxelles 20120101 |
| Combination of the deacetylase inhibitor panobinostat and the multi-kinase inhibitor sorafenib for the treatment of metastatic hepatocellular carcinoma - review of the underlying molecular mechanisms and first case report. | Journal of Cancer 20120101 |
| Genetic variations and haplotype diversity of the UGT1 gene cluster in the Chinese population. | PloS one 20120101 |
| Soft-tissue metastasis revealing a pancreatic adenocarcinoma: one case report and a review of literature. | The Pan African medical journal 20120101 |
| A multimodal approach to the management of neuroendocrine tumour liver metastases. | International journal of hepatology 20120101 |
| Valproic acid inhibits angiogenesis in vitro and glioma angiogenesis in vivo in the brain. | Neurologia medico-chirurgica 20120101 |
| Molecular imaging in therapeutic efficacy assessment of targeted therapy for nonsmall cell lung cancer. | Journal of biomedicine & biotechnology 20120101 |
| Novel therapies in glioblastoma. | Neurology research international 20120101 |
| Current trends in targeted therapies for glioblastoma multiforme. | Neurology research international 20120101 |
| Isoalantolactone induces reactive oxygen species mediated apoptosis in pancreatic carcinoma PANC-1 cells. | International journal of biological sciences 20120101 |
| Novel therapies for aggressive B-cell lymphoma. | Advances in hematology 20120101 |
| High-order SNP combinations associated with complex diseases: efficient discovery, statistical power and functional interactions. | PloS one 20120101 |
| Angiogenesis in Non-Hodgkin's Lymphoma: An Intercategory Comparison of Microvessel Density. | ISRN hematology 20120101 |
| Effect of angiogenesis inhibitor bevacizumab on survival in patients with cancer: a meta-analysis of the published literature. | PloS one 20120101 |
| Cell cycle inhibition without disruption of neurogenesis is a strategy for treatment of aberrant cell cycle diseases: an update. | TheScientificWorldJournal 20120101 |
| Long-term survival after gamma knife radiosurgery in a case of recurrent glioblastoma multiforme: a case report and review of the literature. | Case reports in medicine 20120101 |
| Desmoplastic small round cell tumor: current management and recent findings. | Sarcoma 20120101 |
| A Phase II study of clinical outcomes of 3-week cycles of irinotecan and S-1 in patients with previously untreated metastatic colorectal cancer: influence of the UGT1A1 and CYP2A6 polymorphisms on clinical activity. | Oncology 20120101 |
| An overview of the evidence and mechanisms of herb-drug interactions. | Frontiers in pharmacology 20120101 |
| The role of angiogenesis in the development of proliferative diabetic retinopathy: impact of intravitreal anti-VEGF treatment. | Experimental diabetes research 20120101 |
| The effect of anti-VEGF drugs (bevacizumab and aflibercept) on the survival of patients with metastatic colorectal cancer (mCRC). | OncoTargets and therapy 20120101 |
| Usefulness of FDG, MET and FLT-PET studies for the management of human gliomas. | Journal of biomedicine & biotechnology 20120101 |
| Activating Death Receptor DR5 as a Therapeutic Strategy for Rhabdomyosarcoma. | ISRN oncology 20120101 |
| KRAS, BRAF and PIK3CA mutations and the loss of PTEN expression in Chinese patients with colorectal cancer. | PloS one 20120101 |
| Comprehensive analysis of published phase I/II clinical trials between 1990-2010 in osteosarcoma and Ewing sarcoma confirms limited outcomes and need for translational investment. | Clinical sarcoma research 20120101 |
| Molecular pathogenesis and targeted therapeutics in Ewing sarcoma/primitive neuroectodermal tumours. | Clinical sarcoma research 20120101 |
| Mitochondria: redox metabolism and dysfunction. | Biochemistry research international 20120101 |
| Pemetrexed plus platinum as the first-line treatment option for advanced non-small cell lung cancer: a meta-analysis of randomized controlled trials. | PloS one 20120101 |
| Insufficient radiofrequency ablation promotes angiogenesis of residual hepatocellular carcinoma via HIF-1α/VEGFA. | PloS one 20120101 |
| Combination drug delivery approaches in metastatic breast cancer. | Journal of drug delivery 20120101 |
| Metastatic squamous cell carcinoma of the anus: time for a shift in the treatment paradigm? | ISRN oncology 20120101 |
| In vivo evolution of tumor-derived endothelial cells. | PloS one 20120101 |
| Madarosis: a marker of many maladies. | International journal of trichology 20120101 |
| Prognostic factors for overall survival in patients with metastatic colorectal carcinoma treated with vascular endothelial growth factor-targeting agents. | Asian Pacific journal of cancer prevention : APJCP 20120101 |
| A retrospective study of neoadjuvant FOLFIRINOX in unresectable or borderline-resectable locally advanced pancreatic adenocarcinoma. | BMC cancer 20120101 |
| Prevention of Peritoneal Metastases from Colon Cancer in High-Risk Patients: Preliminary Results of Surgery plus Prophylactic HIPEC. | Gastroenterology research and practice 20120101 |
| Poly(ethylene glycol)-Prodrug Conjugates: Concept, Design, and Applications. | Journal of drug delivery 20120101 |
| Prolonged survival in a patient with neuroendocrine tumor of the cecum and diffuse peritoneal carcinomatosis. | Case reports in gastroenterology 20120101 |
| Carcinomatous pericarditis in 3 breast cancer patients with long-term survival. | Case reports in oncology 20120101 |
| The clone wars - revenge of the metastatic rogue state: the sarcoma paradigm. | Frontiers in oncology 20120101 |
| The chemotherapeutic potential of Terminalia ferdinandiana: Phytochemistry and bioactivity. | Pharmacognosy reviews 20120101 |
| Current knowledge on pancreatic cancer. | Frontiers in oncology 20120101 |
| Locally advanced cancer of the esophagus, current treatment strategies, and future directions. | Frontiers in oncology 20120101 |
| Clear cell carcinoma of the ovary: is there a role of histology-specific treatment? | Journal of experimental & clinical cancer research : CR 20120101 |
| A comprehensive review of the pharmacodynamics, pharmacokinetics, and clinical effects of the neutral endopeptidase inhibitor racecadotril. | Frontiers in pharmacology 20120101 |
| The molecular biology of soft-tissue sarcomas and current trends in therapy. | Sarcoma 20120101 |
| Characterisation of the cell line HC-AFW1 derived from a pediatric hepatocellular carcinoma. | PloS one 20120101 |
| A Primer on the Current State-of-the-Science Neoadjuvant and Adjuvant Therapy for Patients with Locally Advanced Rectal Adenocarcinomas. | International journal of surgical oncology 20120101 |
| Predictive Molecular Tumour Testing: What Are the Obstacles between Bench and Bedside? | Chemotherapy research and practice 20120101 |
| A Pilot Study Assessing the Potential Role of non-CD133 Colorectal Cancer Stem Cells as Biomarkers. | Journal of Cancer 20120101 |
| KRASness and PIK3CAness in patients with advanced colorectal cancer: outcome after treatment with early-phase trials with targeted pathway inhibitors. | PloS one 20120101 |
| The current state of targeted agents in rectal cancer. | International journal of surgical oncology 20120101 |
| Complete Response of Isolated Para-aortic Lymph Node Recurrence from Rectosigmoid Cancer Treated by Chemoradiation Therapy with Capecitabine/Oxaliplatin plus Bevacizumab: A Case Report. | Case reports in oncology 20120101 |
| Namitecan: a hydrophilic camptothecin with a promising preclinical profile. | Current medicinal chemistry 20120101 |
| An unusual presentation of tumor lysis syndrome in a patient with advanced gastric adenocarcinoma: case report and literature review. | Case reports in medicine 20120101 |
| Stroma targeting nuclear imaging and radiopharmaceuticals. | International journal of molecular imaging 20120101 |
| Preparation and in vivo evaluation of liposomal everolimus for lung carcinoma and thyroid carcinoma. | Biological & pharmaceutical bulletin 20120101 |
| Emerging new therapeutic applications of capecitabine as a first-line chemotherapeutic agent in the management of advanced carcinomas other than colorectal carcinoma. | Cancer management and research 20120101 |
| Are platinum agents, paclitaxel and irinotecan effective for clear cell carcinoma of the ovary? DNA damage detected with γH2AX induced by anticancer agents. | Journal of ovarian research 20120101 |
| Surgical Resection for Small Cell Lung Cancer: Pneumonectomy versus Lobectomy. | ISRN surgery 20120101 |
| Phase I study of cetuximab, irinotecan, and vandetanib (ZD6474) as therapy for patients with previously treated metastastic colorectal cancer. | PloS one 20120101 |
| [Observational study on conditions for access to the analysis of KRAS mutation in patients with metastatic colorectal cancer receiving panitumumab treatment]. | Bulletin du cancer 20120101 |
| Early start of chemotherapy after resection of brain metastasis from colon cancer with synchronous multiple liver metastases. | Case reports in oncology 20120101 |
| Possibility of sandwiched liver surgery with molecular targeting drugs, cetuximab and bevacizumab on colon cancer liver metastases: a case report. | World journal of surgical oncology 20120101 |
| XELIRI-bevacizumab versus FOLFIRI-bevacizumab as first-line treatment in patients with metastatic colorectal cancer: a Hellenic Cooperative Oncology Group phase III trial with collateral biomarker analysis. | BMC cancer 20120101 |
| Glutamine: A novel approach to chemotherapy-induced toxicity. | Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology 20120101 |
| Safety verification trials of mFOLFIRI and sequential IRIS + bevacizumab as first- or second-line therapies for metastatic colorectal cancer in Japanese patients. | Oncology 20120101 |
| DNA repair and resistance to topoisomerase I inhibitors: mechanisms, biomarkers and therapeutic targets. | Current medicinal chemistry 20120101 |
| Combined treatment of human colorectal tumor cell lines with chemotherapeutic agents and ionizing irradiation can in vitro induce tumor cell death forms with immunogenic potential. | Journal of immunotoxicology 20120101 |
| Antiemetic control with palonosetron in patients with gastrointestinal cancer receiving a fluoropyrimidine-based regimen in addition to either irinotecan or oxaliplatin: a retrospective study. | Oncology 20120101 |
| Gemcitabine and irinotecan as first-line therapy for carcinoma of unknown primary: results of a multicenter phase II trial. | PloS one 20120101 |
| Irinotecan (CPT-11) chemotherapy alters intestinal microbiota in tumour bearing rats. | PloS one 20120101 |
| Administration of chemotherapy by an arteriovenous fistula in a patient with metastatic rectal cancer after life-threatening, port thrombosis-associated cava superior syndrome. An option for patients without possibility of peripheral or central venous access. | Onkologie 20120101 |
| Colon carcinoma with unusual metastasis to the esophagus manifesting as multiple nodules and Dysphagia: management with systemic chemotherapy. | Case reports in gastroenterology 20120101 |
| Normal serum CA125 half-life and normal serum nadir CA125 level in patients with ovarian cancers. | European journal of gynaecological oncology 20120101 |
| [Temodal--an alkylating cytostatic agent. Effectiveness in patients with malignant gliomas]. | Voprosy onkologii 20120101 |
| p53 Dimers associate with a head-to-tail response element to repress cyclin B transcription. | PloS one 20120101 |
| Preclinical combination therapy of thiarabine plus various clinical anticancer agents. | Nucleosides, nucleotides & nucleic acids 20120101 |
| Silencing of XB130 is associated with both the prognosis and chemosensitivity of gastric cancer. | PloS one 20120101 |
| Second-line irinotecan after cisplatin, fluoropyrimidin and docetaxel for chemotherapy of metastatic gastric cancer. | Asian Pacific journal of cancer prevention : APJCP 20120101 |
| Nedaplatin and irinotecan for patients with recurrent small cell lung cancer. | Journal of experimental therapeutics & oncology 20120101 |
| Impact of the specific mutation in KRAS codon 12 mutated tumors on treatment efficacy in patients with metastatic colorectal cancer receiving cetuximab-based first-line therapy: a pooled analysis of three trials. | Oncology 20120101 |
| Small cell carcinoma of the larynx treated by concurrent chemoradiotherapy: a case report. | Case reports in otolaryngology 20120101 |
| Hepatic arterial infusion with irinotecan, oxaliplatin, and floxuridine plus systemic chemotherapy as first-line treatment of unresectable liver metastases from colorectal cancer. | Onkologie 20120101 |
| Sex differences in the drug therapy for oncologic diseases. | Handbook of experimental pharmacology 20120101 |
| EZN-2208 (PEG-SN38) overcomes ABCG2-mediated topotecan resistance in BRCA1-deficient mouse mammary tumors. | PloS one 20120101 |
| A novel small molecule FL118 that selectively inhibits survivin, Mcl-1, XIAP and cIAP2 in a p53-independent manner, shows superior antitumor activity. | PloS one 20120101 |
| Critical appraisal of bevacizumab in the treatment of metastatic colorectal cancer. | OncoTargets and therapy 20120101 |
| Bevacizumab-induced reversible thrombocytopenia in a patient with adenocarcinoma of colon: rare adverse effect of bevacizumab. | Case reports in oncological medicine 20120101 |
| Novel drugs targeting the epidermal growth factor receptor and its downstream pathways in the treatment of colorectal cancer: a systematic review. | Chemotherapy research and practice 20120101 |
| Primary Small-Cell Carcinoma of the Palate with Cushing's Syndrome: A Case Report. | Case reports in oncological medicine 20120101 |
| Neurodevelopmental disorders. New hope for a devastating neurological disorder. | Science (New York, N.Y.) 20111223 |
| Structure-guided evolution of potent and selective CHK1 inhibitors through scaffold morphing. | Journal of medicinal chemistry 20111222 |
| Sorcin induces a drug-resistant phenotype in human colorectal cancer by modulating Ca(2+) homeostasis. | Cancer research 20111215 |
| Camptothecin (CPT) directly binds to human heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) and inhibits the hnRNP A1/topoisomerase I interaction. | Bioorganic & medicinal chemistry 20111215 |
| Augmented therapeutic efficacy of irinotecan is associated with enhanced drug accumulation. | Cancer letters 20111208 |
| Phase II study of sunitinib as second-line treatment for advanced gastric cancer. | Investigational new drugs 20111201 |
| Role of primary miRNA polymorphic variants in metastatic colon cancer patients treated with 5-fluorouracil and irinotecan. | The pharmacogenomics journal 20111201 |
| Cediranib in combination with various anticancer regimens: results of a phase I multi-cohort study. | Investigational new drugs 20111201 |
| High antimetastatic efficacy of MEN4901/T-0128, a novel camptothecin carboxymethyldextran conjugate. | The Journal of surgical research 20111201 |
| Salvage S-1 monotherapy in metastatic colorectal cancer patients who failed irinotecan-based or oxaliplatin-based chemotherapy. | Medical oncology (Northwood, London, England) 20111201 |
| Primary squamous cell carcinoma associated with ovarian endometriosis: a case report and literature review. | International journal of clinical oncology 20111201 |
| Southwest Oncology Group study S0413: a phase II trial of lapatinib (GW572016) as first-line therapy in patients with advanced or metastatic gastric cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20111201 |
| A case of heavily pretreated rectal cancer with disseminated intravascular coagulation that improved following reintroduction of FOLFOX plus bevacizumab. | International journal of clinical oncology 20111201 |
| Phase 2 study of carboplatin, irinotecan, and bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy. | Cancer 20111201 |
| Sensitivity to previous irinotecan treatment does not predict the efficacy of combination chemotherapy with cetuximab plus irinotecan for wild-type KRAS metastatic colorectal cancer. | European journal of cancer (Oxford, England : 1990) 20111201 |
| Cisplatin and irinotecan combination chemotherapy for advanced thymic carcinoma: evaluation of efficacy and toxicity. | Lung cancer (Amsterdam, Netherlands) 20111201 |
| Arterial therapies of colorectal cancer metastases to the liver. | Abdominal imaging 20111201 |
| Analysis for prognostic factors of 60-day mortality: evaluation of an irinotecan-based phase III trial performed in the first-line treatment of metastatic colorectal cancer. | Clinical colorectal cancer 20111201 |
| Phase I study of sunitinib and irinotecan for patients with recurrent malignant glioma. | Journal of neuro-oncology 20111201 |
| Pharmacokinetic and pharmacogenetic predictive markers of irinotecan activity and toxicity. | Current drug metabolism 20111201 |
| Alternative spliced variants as biomarkers of colorectal cancer. | Current drug metabolism 20111201 |
| A decade of advances in cytotoxic chemotherapy for metastatic colorectal cancer. | Clinical colorectal cancer 20111201 |
| Hepatocyte growth factor suppresses the anticancer effect of irinotecan by decreasing the level of active metabolite in HepG2 cells. | Biochemical pharmacology 20111201 |
| The effect of thalidomide on the pharmacokinetics of irinotecan and metabolites in advanced solid tumor patients. | Cancer chemotherapy and pharmacology 20111201 |
| Novel activity of acriflavine against colorectal cancer tumor cells. | Cancer science 20111201 |
| A phase I study of continuous hepatic arterial infusion of Irinotecan in patients with locally advanced hepatocellular carcinoma. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20111201 |
| Epigenetics and chemoresistance in colorectal cancer: an opportunity for treatment tailoring and novel therapeutic strategies. | Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20111201 |
| Comparison of adjuvant systemic chemotherapy with or without hepatic arterial infusional chemotherapy after hepatic resection for metastatic colorectal cancer. | Annals of surgery 20111201 |
| The oncolytic adenovirus AdΔΔ enhances selective cancer cell killing in combination with DNA-damaging drugs in pancreatic cancer models. | Gene therapy 20111201 |
| Incidence of delayed nausea and vomiting in patients with colorectal cancer receiving irinotecan-based chemotherapy. | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20111201 |
| Enhanced antitumor efficacy of low-dose Etoposide with oncolytic herpes simplex virus in human glioblastoma stem cell xenografts. | Clinical cancer research : an official journal of the American Association for Cancer Research 20111201 |
| Past and present achievements, and future direction of the Gastrointestinal Oncology Study Group (GIOSG), a Division of Japan Clinical Oncology Group (JCOG). | Japanese journal of clinical oncology 20111201 |
| The efficacy and safety of panitumumab administered concomitantly with FOLFIRI or Irinotecan in second-line therapy for metastatic colorectal cancer: the secondary analysis from STEPP (Skin Toxicity Evaluation Protocol With Panitumumab) by KRAS status. | Clinical colorectal cancer 20111201 |
| Pharmacogenetic risk for adverse reactions to irinotecan in the major ethnic populations of Singapore: regulatory evaluation by the health sciences authority. | Drug safety 20111201 |
| Extracellular signal-regulated kinases modulate DNA damage response - a contributing factor to using MEK inhibitors in cancer therapy. | Current medicinal chemistry 20111201 |
| Phase 2 study of capecitabine and irinotecan combination chemotherapy (modified XELIRI regimen) in patients with advanced gastric cancer. | American journal of clinical oncology 20111201 |
| Contrast-enhanced ultrasonography with intraarterial administration of SonoVue for guidance of transarterial chemoembolization: an initial experience. | Medical ultrasonography 20111201 |
| Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells. | Cell death & disease 20111201 |
| Cancer immunotherapy takes a multi-faceted approach to kick the immune system into gear. | The Yale journal of biology and medicine 20111201 |
| When do you need a validated assay? | Bioanalysis 20111201 |
| [A long-term survivor who received S-1-based multidisciplinary therapy for unresectable advanced pancreatic cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20111201 |
| Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
| [Comparison of the toxicities and efficacies of the combination chemotherapy regimens in advanced gastric cancer patients who achieved complete response after chemotherapy]. | The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20111201 |
| Oxaliplatin, irinotecan and cetuximab in advanced gastric cancer. A multicenter phase II trial (Gastric-2) of the Arbeitsgemeinschaft Medikamentose Tumortherapie (AGMT). | Anticancer research 20111201 |
| Impact of chemotherapy for colorectal cancer on regulatory T-cells and tumor immunity. | Anticancer research 20111201 |
| Trans-arterial chemoembolization of metastatic colorectal carcinoma to the liver adopting DC Bead®, drug-eluting bead loaded with irinotecan: results of a phase II clinical study. | Anticancer research 20111201 |
| Salvage chemotherapy for ovarian carcinoma recurring during or after consolidation chemotherapy with paclitaxel. | Anticancer research 20111201 |
| FOLFIRI chemotherapy in patients with advanced non resectable esophageal or junctional adenocarcinoma: a pilot study. | Journal of chemotherapy (Florence, Italy) 20111201 |
| Phase II Study of S-1 Plus Either Irinotecan or Docetaxel for Non-small Cell Lung Cancer Patients Treated with More Than Three Lines of Treatment. | Cancer research and treatment : official journal of Korean Cancer Association 20111201 |
| A Phase II Study of Modified FOLFOX4 for Colorectal Cancer Patients with Peritoneal Carcinomatosis. | Cancer research and treatment : official journal of Korean Cancer Association 20111201 |
| Prognostic factors of second and third line chemotherapy using 5-fu with platinum, irinotecan, and taxane for advanced gastric cancer. | Cancer research and treatment : official journal of Korean Cancer Association 20111201 |
| Selenium is a modulator of circadian clock that protects mice from the toxicity of a chemotherapeutic drug via upregulation of the core clock protein, BMAL1. | Oncotarget 20111201 |
| Differences in the patterns and outcomes of enhanced viral replication between hepatitis C virus and hepatitis B virus in patients with hepatocellular carcinoma during transarterial chemolipiodolization. | The Korean journal of hepatology 20111201 |
| Metastasis to the breast from colonic adenocarcinoma. | Journal of the Korean Surgical Society 20111201 |
| [Study of irinotecan-induced toxicity and its correlation to UGT1A1 gene promoter polymorphisms]. | Zhonghua fu chan ke za zhi 20111201 |
| Abstracts of the 6th cachexia conference, milan, Italy, december 8-10, 2011. | Journal of cachexia, sarcopenia and muscle 20111201 |
| Inflammatory macrophages induce Nrf2 transcription factor-dependent proteasome activity in colonic NCM460 cells and thereby confer anti-apoptotic protection. | The Journal of biological chemistry 20111125 |
| Methylenetetrahydrofolate reductase genetic polymorphisms and toxicity to 5-FU-based chemoradiation in rectal cancer. | British journal of cancer 20111122 |
| Cisplatin, irinotecan, and bevacizumab for untreated extensive-stage small-cell lung cancer: CALGB 30306, a phase II study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20111120 |
| Anticancer drug irinotecan inhibits homomeric 5-HT3A and heteromeric 5-HT3AB receptor responses. | Biochemical and biophysical research communications 20111118 |
| MC70 potentiates doxorubicin efficacy in colon and breast cancer in vitro treatment. | European journal of pharmacology 20111116 |
| KRAS and BRAF mutations and PTEN expression do not predict efficacy of cetuximab-based chemoradiotherapy in locally advanced rectal cancer. | International journal of radiation oncology, biology, physics 20111115 |
| Cytokeratin-19 and mammaglobin gene expression in circulating tumor cells from metastatic breast cancer patients enrolled in North Central Cancer Treatment Group trials, N0234/336/436/437. | Clinical cancer research : an official journal of the American Association for Cancer Research 20111115 |
| Small-cell lung cancer. | Lancet (London, England) 20111112 |
| An EGFR inhibitor enhances the efficacy of SN38, an active metabolite of irinotecan, in SN38-refractory gastric carcinoma cells. | British journal of cancer 20111108 |
| Preoperative chemoradiation with cetuximab, irinotecan, and capecitabine in patients with locally advanced resectable rectal cancer: a multicenter Phase II study. | International journal of radiation oncology, biology, physics 20111101 |
| Bevacizumab-related arterial hypertension as a predictive marker in metastatic colorectal cancer patients. | Cancer chemotherapy and pharmacology 20111101 |
| Amrubicin for the treatment of neuroendocrine carcinoma of the gastrointestinal tract: a retrospective analysis of five cases. | Cancer chemotherapy and pharmacology 20111101 |
| [An evaluation of fatigue in patients with glioblastoma relapse treated with the combination of irinotecan-bevacizumab]. | Revue neurologique 20111101 |
| Klotho predicts good clinical outcome in patients with limited-disease small cell lung cancer who received surgery. | Lung cancer (Amsterdam, Netherlands) 20111101 |
| Clinical efficacy of chemotherapy combined with verapamil in metastatic colorectal patients. | Cell biochemistry and biophysics 20111101 |
| Synergistic effects of irinotecan and flavonoids on Ehrlich ascites tumour-bearing mice. | Basic & clinical pharmacology & toxicology 20111101 |
| The status of EGFR-associated genes could predict the outcome and tumor response of chemo-refractory metastatic colorectal patients using cetuximab and chemotherapy. | Journal of surgical oncology 20111101 |
| Cetuximab after bevacizumab in metastatic colorectal cancer: is it the best sequence? | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20111101 |
| Influence of body mass index on outcome in advanced colorectal cancer patients receiving chemotherapy with or without targeted therapy. | European journal of cancer (Oxford, England : 1990) 20111101 |
| PDZK1 regulates breast cancer resistance protein in small intestine. | Drug metabolism and disposition: the biological fate of chemicals 20111101 |
| Prognostic value of resection of primary tumor in patients with stage IV colorectal cancer: retrospective analysis of two randomized studies and a review of the literature. | Annals of surgical oncology 20111101 |
| Phase II study of first-line FOLFIRI for progressive metastatic well-differentiated pancreatic endocrine carcinoma. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20111101 |
| The polypyrimidine/polypurine motif in the mouse mu opioid receptor gene promoter is a supercoiling-regulatory element. | Gene 20111101 |
| Therapeutic targeting of subdural medulloblastomas using human neural stem cells expressing carboxylesterase. | Cancer gene therapy 20111101 |
| Single nucleotide polymorphisms of ABCC5 and ABCG1 transporter genes correlate to irinotecan-associated gastrointestinal toxicity in colorectal cancer patients: a DMET microarray profiling study. | Cancer biology & therapy 20111101 |
| MicroRNA-451 is involved in the self-renewal, tumorigenicity, and chemoresistance of colorectal cancer stem cells. | Stem cells (Dayton, Ohio) 20111101 |
| 1,1-Diarylalkenes as anticancer agents: dual inhibitors of tubulin polymerization and phosphodiesterase 4. | Bioorganic & medicinal chemistry 20111101 |
| Structure of an aprataxin-DNA complex with insights into AOA1 neurodegenerative disease. | Nature structural & molecular biology 20111101 |
| Preclinical study of treatment response in HCT-116 cells and xenografts with (1) H-decoupled (31) P MRS. | NMR in biomedicine 20111101 |
| Looking through the vascular normalization window: timing antiangiogenic treatment and chemotherapy with (99m)Tc-annexin A5. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20111101 |
| Cetuximab plus FOLFIRINOX (ERBIRINOX) as first-line treatment for unresectable metastatic colorectal cancer: a phase II trial. | The oncologist 20111101 |
| (99)mTc-(CO)(3) His-annexin A5 micro-SPECT demonstrates increased cell death by irinotecan during the vascular normalization window caused by bevacizumab. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20111101 |
| Carcinomas of an unknown primary origin--diagnosis and treatment. | Nature reviews. Clinical oncology 20111101 |
| [Molecular determinants of response to topoisomerase I inhibitors]. | Bulletin du cancer 20111101 |
| Isolation and characterization of a murine P388 leukemia line resistant to clofarabine. | Nucleosides, nucleotides & nucleic acids 20111101 |
| Intravenous KITENIN shRNA injection suppresses hepatic metastasis and recurrence of colon cancer in an orthotopic mouse model. | Journal of Korean medical science 20111101 |
| Lipid-based nanoformulation of irinotecan: dual mechanism of action allows for combination chemo/angiogenic therapy. | Nanomedicine (London, England) 20111101 |
| [Chemotherapy-induced stomatitis and diarrhea]. | Gan to kagaku ryoho. Cancer & chemotherapy 20111101 |
| Evaluation of metabolism-mediated herb-drug interactions. | Archives of pharmacal research 20111101 |
| [A case of advanced gastric cancer with splenic vein thrombus successfully treated with S-1 plus CPT-11 neoadjuvant chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20111101 |
| [A case of gastric neuroendocrine cell carcinoma successfully treated by neoadjuvant chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20111101 |
| [A case report of pathologically complete response of rectal cancer after preoperative treatment of CPT-11, S-1, and radiation therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20111101 |
| Identification of carboxylesterases expressed in rat intestine and effects of their hydrolyzing activity in predicting first-pass metabolism of ester prodrugs. | Die Pharmazie 20111101 |
| Development and pharmacological evaluation of a PEG based nanoparticulate camptothecin analog for oral administration. | Current drug delivery 20111101 |
| Secondary gliosarcoma after the treatment of primary glioblastoma multiforme. | North American journal of medical sciences 20111101 |
| Establishment of pemetrexed-resistant non-small cell lung cancer cell lines. | Cancer letters 20111028 |
| Synthesis of uronic-noeurostegine--a potent bacterial β-glucuronidase inhibitor. | Organic & biomolecular chemistry 20111026 |
| Discriminant analysis of ¹⁸F-fluorothymidine kinetic parameters to predict survival in patients with recurrent high-grade glioma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20111015 |
| NKX3.1 contributes to S phase entry and regulates DNA damage response (DDR) in prostate cancer cell lines. | Biochemical and biophysical research communications 20111014 |
| Phase I study of irinotecan and gefitinib in patients with gefitinib treatment failure for non-small cell lung cancer. | British journal of cancer 20111011 |
| Influence of pharmacogenetic variability on the pharmacokinetics and toxicity of the aurora kinase inhibitor danusertib. | Investigational new drugs 20111001 |
| Phase II study of irinotecan/S-1 combination chemotherapy for patients with oxaliplatin-refractory colorectal cancer. | Investigational new drugs 20111001 |
| Simvastatin enhances irinotecan-induced apoptosis in human non-small cell lung cancer cells by inhibition of proteasome activity. | Investigational new drugs 20111001 |
| Gender-related survival differences associated with polymorphic variants of estrogen receptor-β (ERβ) in patients with metastatic colon cancer. | The pharmacogenomics journal 20111001 |
| A case of primary uterine cervical neuroendocrine tumor with meningeal carcinomatosis confirmed by diagnostic imaging and autopsy. | International journal of clinical oncology 20111001 |
| Transcatheter arterial chemoembolization with docetaxel-loaded microspheres controls heavily pretreated unresectable liver metastases from colorectal cancer: a case study. | International journal of clinical oncology 20111001 |
| Cetuximab enhances the activities of irinotecan on gastric cancer cell lines through downregulating the EGFR pathway upregulated by irinotecan. | Cancer chemotherapy and pharmacology 20111001 |
| A phase I study of combination therapy with S-1 and irinotecan in patients with previously untreated metastatic or recurrent colorectal cancer. | Cancer chemotherapy and pharmacology 20111001 |
| Comparison of liposomal cisplatin versus cisplatin in non-squamous cell non-small-cell lung cancer. | Cancer chemotherapy and pharmacology 20111001 |
| Salvage chemotherapy of biweekly irinotecan plus S-1 (biweekly IRIS) in previously treated patients with advanced gastric cancer. | Cancer chemotherapy and pharmacology 20111001 |
| Retrospective analysis of the international standard-dose FOLFIRI (plus bevacizumab) regimen in Japanese patients with unresectable advanced or recurrent colorectal carcinoma. | International journal of clinical oncology 20111001 |
| Is resection of colorectal liver metastases after a second-line chemotherapy regimen justified? | Cancer 20111001 |
| Irinotecan-induced alterations in intestinal cell kinetics and extracellular matrix component expression in the Dark Agouti rat. | International journal of experimental pathology 20111001 |
| Genotype-directed, dose-finding study of irinotecan in cancer patients with UGT1A1*28 and/or UGT1A1*6 polymorphisms. | Cancer science 20111001 |
| Clinical effects of irinotecan hydrochloride in combination with cisplatin as neoadjuvant chemotherapy in locally advanced cervical cancer. | Gynecologic oncology 20111001 |
| Survival advantage for irinotecan versus best supportive care as second-line chemotherapy in gastric cancer--a randomised phase III study of the Arbeitsgemeinschaft Internistische Onkologie (AIO). | European journal of cancer (Oxford, England : 1990) 20111001 |
| Tumor-specific targeting of pancreatic cancer with Shiga toxin B-subunit. | Molecular cancer therapeutics 20111001 |
| [Preoperative radiochemotherapy for rectal cancer: forecasting the next steps through ongoing and forthcoming studies]. | Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20111001 |
| Conversion chemotherapy using cetuximab plus FOLFIRI followed by bevacizumab plus mFOLFOX6 in patients with unresectable liver metastases from colorectal cancer. | Japanese journal of clinical oncology 20111001 |
| Transient elevation of international normalized ratio during cisplatin-based chemotherapy in patients who are taking warfarin. | The Annals of pharmacotherapy 20111001 |
| [Chemotherapy and rectal cancer]. | Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20111001 |
| Intraperitoneally administered irinotecan with 5-fluorouracil impair wound healing of colonic anastomoses in a rat model: an experimental study. | Techniques in coloproctology 20111001 |
| FOLFIRINOX: a small step or a great leap forward? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20111001 |
| Sequential versus combination chemotherapy for the treatment of advanced colorectal cancer (FFCD 2000-05): an open-label, randomised, phase 3 trial. | The Lancet. Oncology 20111001 |
| Cetuximab pharmacokinetics influences progression-free survival of metastatic colorectal cancer patients. | Clinical cancer research : an official journal of the American Association for Cancer Research 20111001 |
| Efficacy and safety of bevacizumab plus chemotherapy in Chinese patients with metastatic colorectal cancer: a randomized phase III ARTIST trial. | Chinese journal of cancer 20111001 |
| ERas enhances resistance to CPT-11 in gastric cancer. | Anticancer research 20111001 |
| The role of chemotherapy in metastatic gastric cancer. | Anticancer research 20111001 |
| Metabolic activation of irinotecan during intra-arterial chemotherapy of metastatic colorectal cancer. | Anticancer research 20111001 |
| A safety and toxicity assessment of the administration of multiple intracerebral injections of irinotecan or doxorubicin drug-eluting beads. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20111001 |
| Durable remission of inoperable liver metastasis from rectal cancer after hepatic arterial infusion of oxaliplatin and 5-fluorouracil in combination with intravenous cetuximab. | Current oncology (Toronto, Ont.) 20111001 |
| Localized skin necrosis of steroid-induced striae distensae: an unusual complication of bevacizumab and irinotecan therapy. | Archives of dermatology 20111001 |
| Colorectal cancer with multiple metastases: is palliative surgery needed? | Journal of the Korean Society of Coloproctology 20111001 |
| Accurate determination of the anticancer prodrug simmitecan and its active metabolite chimmitecan in various plasma samples based on immediate deactivation of blood carboxylesterases. | Journal of chromatography. A 20110923 |
| Cancer-stroma targeting therapy by cytotoxic immunoconjugate bound to the collagen 4 network in the tumor tissue. | Bioconjugate chemistry 20110921 |
| Total synthesis of 7-ethyl-10-hydroxycamptothecin (SN38) and its application to the development of C18-functionalized camptothecin derivatives. | Chemistry (Weinheim an der Bergstrasse, Germany) 20110905 |
| Clinical, laboratory and molecular factors predicting chemotherapy efficacy and toxicity in colorectal cancer. | Critical reviews in oncology/hematology 20110901 |
| Effect of radiation on the penetration of irinotecan in rat cerebrospinal fluid. | Cancer chemotherapy and pharmacology 20110901 |
| Development and characterization of a novel lipid nanocapsule formulation of Sn38 for oral administration. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20110901 |
| Sagopilone (ZK-EPO, ZK 219477) for recurrent glioblastoma. A phase II multicenter trial by the European Organisation for Research and Treatment of Cancer (EORTC) Brain Tumor Group. | Annals of oncology : official journal of the European Society for Medical Oncology 20110901 |
| Characteristics and prognosis of patients with colorectal cancer-associated brain metastases in the era of modern systemic chemotherapy. | Journal of neuro-oncology 20110901 |
| Closed abdomen hyperthermic intraperitoneal chemotherapy with irinotecan and mitomycin C: a phase I study. | Annals of surgical oncology 20110901 |
| Potent and sustained inhibition of HIF-1α and downstream genes by a polyethyleneglycol-SN38 conjugate, EZN-2208, results in anti-angiogenic effects. | Angiogenesis 20110901 |
| Unresectable peritoneal carcinomatosis from colorectal cancer: a single center experience. | Journal of surgical oncology 20110901 |
| Impact of therapy on quality of life, neurocognitive function and their correlates in glioblastoma multiforme: a review. | Journal of neuro-oncology 20110901 |
| Activity of aspirin analogues and vanillin in a human colorectal cancer cell line. | Oncology reports 20110901 |
| AAPS workshop report: strategies to address therapeutic protein-drug interactions during clinical development. | The AAPS journal 20110901 |
| Impact of induction chemotherapy on estimated risk of radiation pneumonitis in small cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110901 |
| Oxidative stress mediates through apoptosis the anticancer effect of phospho-nonsteroidal anti-inflammatory drugs: implications for the role of oxidative stress in the action of anticancer agents. | The Journal of pharmacology and experimental therapeutics 20110901 |
| Association between deficient mismatch repair system and efficacy to irinotecan-containing chemotherapy in metastatic colon cancer. | Cancer science 20110901 |
| Human immunoglobulin G levels of viruses and associated glioma risk. | Cancer causes & control : CCC 20110901 |
| Glucagon-like peptide-1 receptor activation inhibits growth and augments apoptosis in murine CT26 colon cancer cells. | Endocrinology 20110901 |
| Snapback primer genotyping of the Gilbert syndrome UGT1A1 (TA)(n) promoter polymorphism by high-resolution melting. | Clinical chemistry 20110901 |
| Comparative effectiveness of different chemotherapeutic regimens on survival of people aged 66 and older with stage III colon cancer: a 'real world' analysis using Surveillance, Epidemiology, and End Results-Medicare data. | Journal of the American Geriatrics Society 20110901 |
| Post-marketing surveillance (PMS) of all patients treated with irinotecan in Japan: clinical experience and ADR profile of 13,935 patients. | Japanese journal of clinical oncology 20110901 |
| An open-label, single-arm, phase 2 trial of panitumumab plus FOLFIRI as second-line therapy in patients with metastatic colorectal cancer. | Clinical colorectal cancer 20110901 |
| Durable complete responses in metastatic colorectal cancer treated with chemotherapy alone. | Clinical colorectal cancer 20110901 |
| Body surface area-based dosing of 5-fluoruracil results in extensive interindividual variability in 5-fluorouracil exposure in colorectal cancer patients on FOLFOX regimens. | Clinical colorectal cancer 20110901 |
| Simplified prognostic model in patients with oxaliplatin-based or irinotecan-based first-line chemotherapy for metastatic colorectal cancer: a GERCOR study. | The oncologist 20110901 |
| Five hundred patients with Merkel cell carcinoma evaluated at a single institution. | Annals of surgery 20110901 |
| Panipenem does not alter the pharmacokinetics of the active metabolite of irinotecan SN-38 and inactive metabolite SN-38 glucuronide (SN-38G) in rats. | Anticancer research 20110901 |
| Topoisomerase I expression in tumors as a biological marker for CPT-11 chemosensitivity in patients with colorectal cancer. | Surgery today 20110901 |
| [Efforts toward qualitative and quantitative improvements of cancer clinical trials at regional designated cancer care hospitals-through full support for cancer clinical trials by oncology pharmacy specialist and data manager]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110901 |
| [CPT-11 chemotherapy for a hemodialysis patient with small-cell lung cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110901 |
| [Irinotecan as second-line chemotherapy for 5-FU-resistant gastric cancer with disseminated intravascular coagulation: a case report]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110901 |
| A combined experimental and mathematical approach for molecular-based optimization of irinotecan circadian delivery. | PLoS computational biology 20110901 |
| Diarrhea. | Disease-a-month : DM 20110901 |
| Irinotecan as the key chemotherapeutic agent in second-line treatment of metastatic gastric cancer after failure of first-line S-1 or S-1/CDDP therapy. | Gan to kagaku ryoho. Cancer & chemotherapy 20110901 |
| Modified FOLFIRI as Second-Line Chemotherapy after Failure of Modified FOLFOX-4 in Advanced Gastric Cancer. | Cancer research and treatment : official journal of Korean Cancer Association 20110901 |
| Heat shock protein as molecular targets for breast cancer therapeutics. | Journal of breast cancer 20110901 |
| [A relapse of small-cell lung cancer ten years after concomitant chemoradiotherapy followed by high-dose chemotherapy with autologous peripheral blood stem cell transfusion]. | Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20110901 |
| FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. | The New England journal of medicine 20110825 |
| ABCC multidrug transporters in childhood neuroblastoma: clinical and biological effects independent of cytotoxic drug efflux. | Journal of the National Cancer Institute 20110817 |
| Anti-tumor activity of liposome encapsulated fluoroorotic acid as a single agent and in combination with liposome irinotecan. | Journal of controlled release : official journal of the Controlled Release Society 20110810 |
| Fatal infusion reaction to cetuximab: the need for predictive risk factors and safer patient selection. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110810 |
| Human epidermal growth factor eyedrops for cetuximab-related filamentary keratitis. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110810 |
| Docetaxel and capecitabine for advanced gastric cancer: investigating dose-dependent efficacy in two patient cohorts. | British journal of cancer 20110809 |
| [Pathological changes of rectal cancer after irinotecan, 5-fluorouracil or combined short-term radiotherapy]. | Zhonghua yi xue za zhi 20110809 |
| Modulation of pancreatic cancer chemoresistance by inhibition of TAK1. | Journal of the National Cancer Institute 20110803 |
| A systematic review of FOLFOXIRI chemotherapy for the first-line treatment of metastatic colorectal cancer: improved efficacy at the cost of increased toxicity. | Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20110801 |
| Phase II study of combination chemotherapy with irinotecan and cetuximab for pretreated metastatic colorectal cancer harboring wild-type KRAS. | Investigational new drugs 20110801 |
| UGT1A1*1/*28 and *1/*6 genotypes have no effects on the efficacy and toxicity of FOLFIRI in Japanese patients with advanced colorectal cancer. | Cancer chemotherapy and pharmacology 20110801 |
| The histone deacetylase inhibitor PXD101 increases the efficacy of irinotecan in in vitro and in vivo colon cancer models. | Cancer chemotherapy and pharmacology 20110801 |
| Cytotoxicity and genotoxicity of capecitabine in head and neck cancer and normal cells. | Molecular biology reports 20110801 |
| Successful surgical treatment and chemotherapy for ovarian cancer in a patient with idiopathic thrombocytopenic purpura. | International journal of clinical oncology 20110801 |
| A German multicenter, randomized phase III trial comparing irinotecan-carboplatin with etoposide-carboplatin as first-line therapy for extensive-disease small-cell lung cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20110801 |
| Biweekly cetuximab and irinotecan as second-line therapy in patients with gastro-esophageal cancer previously treated with platinum. | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20110801 |
| Retrospective analysis of cetuximab monotherapy for patients with irinotecan-intolerant metastatic colorectal cancer. | International journal of clinical oncology 20110801 |
| A FGFR2 inhibitor, Ki23057, enhances the chemosensitivity of drug-resistant gastric cancer cells. | Cancer letters 20110801 |
| A phase II study of biweekly mitomycin C and irinotecan combination therapy in patients with fluoropyrimidine-resistant advanced gastric cancer: a report from the Gastrointestinal Oncology Group of the Japan Clinical Oncology Group (JCOG0109-DI Trial). | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20110801 |
| Second-line chemotherapy in patients with primary unknown cancer. | Journal of cancer research and clinical oncology 20110801 |
| Ethnic differences in the metabolism, toxicology and efficacy of three anticancer drugs. | Expert opinion on drug metabolism & toxicology 20110801 |
| Growth response of human colorectal tumour cell lines to treatment with afatinib (BIBW2992), an irreversible erbB family blocker, and its association with expression of HER family members. | International journal of oncology 20110801 |
| Clinical practice guidelines for the prevention and treatment of EGFR inhibitor-associated dermatologic toxicities. | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20110801 |
| Overcoming hypoxia-induced apoptotic resistance through combinatorial inhibition of GSK-3β and CDK1. | Cancer research 20110801 |
| Pulmonary artery chemoembolization in a sheep model: Evaluation of performance and safety of irinotecan eluting beads (DEB-IRI). | Journal of biomedical materials research. Part B, Applied biomaterials 20110801 |
| Single-agent irinotecan or FOLFIRI as second-line chemotherapy for advanced colorectal cancer; results of a randomised phase II study (DaVINCI) and meta-analysis [corrected]. | European journal of cancer (Oxford, England : 1990) 20110801 |
| Quinacrine sensitizes hepatocellular carcinoma cells to TRAIL and chemotherapeutic agents. | Cancer biology & therapy 20110801 |
| Results of two bi-institutional prospective studies using intraperitoneal oxaliplatin with or without irinotecan during HIPEC after cytoreductive surgery for colorectal carcinomatosis. | Annals of surgery 20110801 |
| Predictors of the efficacy of FOLFIRI plus bevacizumab as second-line treatment in metastatic colorectal cancer patients. | Surgery today 20110801 |
| A phase II trial of bevacizumab plus everolimus for patients with refractory metastatic colorectal cancer. | The oncologist 20110801 |
| Using bevacizumab in the fight against malignant glioma: first results in Asian patients. | Hong Kong medical journal = Xianggang yi xue za zhi 20110801 |
| [Colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110801 |
| [Analysis of the correlation with KRAS gene mutation status and the benefit of cetuximab plus irinotecan as third- line chemotherapy for the Treatment of unresectable metastatic colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110801 |
| [A case of advanced gastric cancer with multiple liver metastasis responding to S-1 and irinotecan combination therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110801 |
| [A case of sigmoid colon cancer with temporary dysarthria associated with irinotecan]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110801 |
| The organotelluride catalyst LAB027 prevents colon cancer growth in the mice. | Cell death & disease 20110801 |
| [Multimodal therapy for colon cancer: state of the art]. | Zentralblatt fur Chirurgie 20110801 |
| [Efficacy of trsatuzumab (Herceptin) combined with FOLFIRI regimen in the treatment of HER2-positive advanced gastric cancer]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20110801 |
| Germline genetic testing to predict drug response and toxicity in oncology--reality or fiction? | Annals of the Academy of Medicine, Singapore 20110801 |
| Up-regulation of cyclooxygenase-2-derived prostaglandin E(2) in colon cancer cells resistant to 5-fluorouracil. | Journal of the Korean Surgical Society 20110801 |
| Alcohol-, diol-, and carbohydrate-substituted indenoisoquinolines as topoisomerase I inhibitors: investigating the relationships involving stereochemistry, hydrogen bonding, and biological activity. | Journal of medicinal chemistry 20110728 |
| Clinical implications of UGT1A1*28 genotype testing in colorectal cancer patients. | Cancer 20110715 |
| Preclinical to clinical development of the novel camptothecin nanopharmaceutical CRLX101. | Journal of controlled release : official journal of the Controlled Release Society 20110715 |
| EGFR gene copy number assessment from areas with highest EGFR expression predicts response to anti-EGFR therapy in colorectal cancer. | British journal of cancer 20110712 |
| Correlation of capecitabine-induced skin toxicity with treatment efficacy in patients with metastatic colorectal cancer: results from the German AIO KRK-0104 trial. | British journal of cancer 20110712 |
| Impact of young age on treatment efficacy and safety in advanced colorectal cancer: a pooled analysis of patients from nine first-line phase III chemotherapy trials. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110710 |
| Chemotherapy: Metastatic pancreatic cancer--is FOLFIRINOX the new standard? | Nature reviews. Clinical oncology 20110705 |
| Enhancing adherence to capecitabine chemotherapy by means of multidisciplinary pharmaceutical care. | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20110701 |
| Can localised (19)F magnetic resonance spectroscopy pharmacokinetics of 5FU in colorectal metastases predict clinical response? | Cancer chemotherapy and pharmacology 20110701 |
| Pharmacokinetic results of a phase I trial of sorafenib in combination with dacarbazine in patients with advanced solid tumors. | Cancer chemotherapy and pharmacology 20110701 |
| Α multicenter phase II study of pegylated liposomal doxorubicin in combination with irinotecan as second-line treatment of patients with refractory small-cell lung cancer. | Cancer chemotherapy and pharmacology 20110701 |
| Treatment of children with recurrent high grade gliomas with a bevacizumab containing regimen. | Journal of neuro-oncology 20110701 |
| Metabolic drug interactions between antidepressants and anticancer drugs: focus on selective serotonin reuptake inhibitors and hypericum extract. | Current drug metabolism 20110701 |
| Differentiated human colorectal cancer cells protect tumor-initiating cells from irinotecan. | Gastroenterology 20110701 |
| New concept of cytotoxic immunoconjugate therapy targeting cancer-induced fibrin clots. | Cancer science 20110701 |
| Randomized phase II trial of first-line treatment with tailored irinotecan and S-1 therapy versus S-1 monotherapy for advanced or recurrent gastric carcinoma (JFMC31-0301). | Anti-cancer drugs 20110701 |
| Phase I trial of capecitabine plus everolimus (RAD001) in patients with previously treated metastatic gastric cancer. | Cancer chemotherapy and pharmacology 20110701 |
| Adjuvant treatment of colon cancer: what is next? | Current opinion in oncology 20110701 |
| Cetuximab in the treatment of patients with colorectal cancer. | Expert opinion on biological therapy 20110701 |
| Clarification of clinical features of interstitial lung disease induced by irinotecan based on postmarketing surveillance data and spontaneous reports. | Anti-cancer drugs 20110701 |
| Novel acrylonitrile derivatives, YHO-13177 and YHO-13351, reverse BCRP/ABCG2-mediated drug resistance in vitro and in vivo. | Molecular cancer therapeutics 20110701 |
| Oxaliplatin, irinotecan, and gemcitabine: a novel combination in the therapy of progressed, relapsed, or refractory tumors in children. | Journal of pediatric hematology/oncology 20110701 |
| Development of thermosensitive poly(n-isopropylacrylamide-co-((2-dimethylamino) ethyl methacrylate))-based nanoparticles for controlled drug release. | Nanotechnology 20110701 |
| Comparative proteomic analysis of irinotecan-sensitive colorectal carcinoma cell line and its chemoresistant counterpart. | Anti-cancer drugs 20110701 |
| Personalized medicine: new genomics, old lessons. | Human genetics 20110701 |
| [Assessment of quality of life by questionnaires between S-1/CPT-11 and mFOLFOX6 in patients with advanced colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110701 |
| [Protective effects of d-chlorpheniramine maleate pre-treatment against acute side effects of Irinotecan(CPT- 11)]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110701 |
| [A case of interstitial pneumonia induced by CPT-11 for local recurrence of rectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110701 |
| A genotype-directed phase I-IV dose-finding study of irinotecan in combination with fluorouracil/leucovorin as first-line treatment in advanced colorectal cancer. | British journal of cancer 20110628 |
| Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial. | Lancet (London, England) 20110618 |
| The addition of bevacizumab to standard radiation therapy and temozolomide followed by bevacizumab, temozolomide, and irinotecan for newly diagnosed glioblastoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110615 |
| Vascular phenotypes in primary non-small cell lung carcinomas and matched brain metastases. | British journal of cancer 20110607 |
| A Q-TWiST analysis comparing panitumumab plus best supportive care (BSC) with BSC alone in patients with wild-type KRAS metastatic colorectal cancer. | British journal of cancer 20110607 |
| Recurrence and survival after pathologic complete response to preoperative therapy followed by surgery for gastric or gastrooesophageal adenocarcinoma. | British journal of cancer 20110607 |
| Phase I study of PD 0332991, a cyclin-dependent kinase inhibitor, administered in 3-week cycles (Schedule 2/1). | British journal of cancer 20110607 |
| Intermittent versus continuous oxaliplatin and fluoropyrimidine combination chemotherapy for first-line treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial. | The Lancet. Oncology 20110604 |
| Cetuximab plus irinotecan after irinotecan failure in elderly metastatic colorectal cancer patients: clinical outcome according to KRAS and BRAF mutational status. | Critical reviews in oncology/hematology 20110601 |
| A Phase 1 study of UCN-01 in combination with irinotecan in patients with resistant solid tumor malignancies. | Cancer chemotherapy and pharmacology 20110601 |
| Correlation of MRI sequences to assess progressive glioblastoma multiforme treated with bevacizumab. | Journal of neuro-oncology 20110601 |
| Capecitabine-based chemotherapy for metastatic colorectal cancer. | Journal of cancer research and clinical oncology 20110601 |
| Cetuximab with irinotecan, folinic acid and 5-fluorouracil as first-line treatment in advanced gastroesophageal cancer: a prospective multi-center biomarker-oriented phase II study. | Annals of oncology : official journal of the European Society for Medical Oncology 20110601 |
| Evaluation of chemotherapy-associated liver injury in patients with colorectal cancer liver metastases using indocyanine green clearance testing. | Annals of surgical oncology 20110601 |
| Advances in MRI assessment of gliomas and response to anti-VEGF therapy. | Current neurology and neuroscience reports 20110601 |
| Common variant in 6q26-q27 is associated with distal colon cancer in an Asian population. | Gut 20110601 |
| Patterns of progression in malignant glioma following anti-VEGF therapy: perceptions and evidence. | Current neurology and neuroscience reports 20110601 |
| Neuroendocrine tumors of the stomach: chemotherapy with cisplatin plus irinotecan is effective for gastric poorly-differentiated neuroendocrine carcinoma. | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20110601 |
| Survival and prognosticators of gastric cancer that recurs after adjuvant chemotherapy with S-1. | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20110601 |
| Association of fluoropyrimidines, platinum agents, taxanes, and irinotecan in any line of chemotherapy with survival in patients with advanced gastric cancer. | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20110601 |
| Phase II study of S-1, an oral fluoropyrimidine, in patients with advanced or recurrent cervical cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20110601 |
| Enhancement of CPT-11 antitumor activity by adenovirus-mediated expression of β-glucuronidase in tumors. | Cancer gene therapy 20110601 |
| Adjuvant systemic chemotherapy for Stage II and III colon cancer after complete resection: an updated practice guideline. | Clinical oncology (Royal College of Radiologists (Great Britain)) 20110601 |
| Standard perioperative management in gastrointestinal surgery. | Langenbeck's archives of surgery 20110601 |
| Clinical applicability of sequence variations in genes related to drug metabolism. | Current drug metabolism 20110601 |
| Phase II trial of the combination of carboplatin and irinotecan in elderly patients with small-cell lung cancer. | European journal of cancer (Oxford, England : 1990) 20110601 |
| Antiproliferative and proapoptotic activity of CLM3, a novel multiple tyrosine kinase inhibitor, alone and in combination with SN-38 on endothelial and cancer cells. | Biochemical pharmacology 20110601 |
| Combination radioimmunotherapy and chemoimmunotherapy involving different or the same targets improves therapy of human pancreatic carcinoma xenograft models. | Molecular cancer therapeutics 20110601 |
| BEYOND KRAS: Other markers and potential treatment strategies for KRAS mutant and wild-type patients. | Current treatment options in oncology 20110601 |
| CD44-targeting for antitumor drug delivery: a new SN-38-hyaluronan bioconjugate for locoregional treatment of peritoneal carcinomatosis. | Current cancer drug targets 20110601 |
| Early therapy evaluation of combined cetuximab and irinotecan in orthotopic pancreatic tumor xenografts by dynamic contrast-enhanced magnetic resonance imaging. | Molecular imaging 20110601 |
| Bevacizumab enhances the therapeutic efficacy of Irinotecan against human head and neck squamous cell carcinoma xenografts. | Oral oncology 20110601 |
| Intensive chemotherapy of metastatic colorectal cancer: weighing between safety and clinical efficacy: Evaluation of Masi G, Loupakis F, Salvatore L, et al. Bevacizumab with FOLFOXIRI (irinotecan, oxaliplatin, fluorouracil, and folinate) as first-line treatment for metastatic colorectal cancer: a phase 2 trial. Lancet Oncol 2010;11:845-52. | Expert opinion on biological therapy 20110601 |
| Novel sulfobutyl ether cyclodextrin gradient leads to highly active liposomal irinotecan formulation. | The Journal of pharmacy and pharmacology 20110601 |
| Other options in the treatment of advanced breast cancer. | Seminars in oncology 20110601 |
| O-(2-18F-fluoroethyl)-L-tyrosine PET predicts failure of antiangiogenic treatment in patients with recurrent high-grade glioma. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110601 |
| Early clinical development of ARQ 197, a selective, non-ATP-competitive inhibitor targeting MET tyrosine kinase for the treatment of advanced cancers. | The oncologist 20110601 |
| Tumor status at 12 weeks predicts survival in advanced colorectal cancer: findings from NCCTG N9741. | The oncologist 20110601 |
| [Multiple Sister Mary Joseph's nodules in a patient with gastric cancer]. | Deutsche medizinische Wochenschrift (1946) 20110601 |
| [Clinical efficacy and safety of CPT-11+CDDP therapy as third-line chemotherapy for advanced and recurrent gastric cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110601 |
| [Primary adenocarcinoma of small intestine with peritoneal dissemination treated with S-1 and CPT-11 combination chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110601 |
| Use of bevacizumab in metastatic colorectal cancer: report from the Mexican opinion and analysis forum on colorectal cancer treatment with bevacizumab (September 2009). | Drugs in R&D 20110601 |
| Estimating preclinical efficacy targets utilizing cetuximab efficacy in KRAS mutant and wild-type colorectal cancer models. | Anticancer research 20110601 |
| Bevacizumab in combination with irinotecan, 5-fluorouracil and leucovorin given as first-line treatment of metastatic colorectal cancer. | Anti-cancer drugs 20110601 |
| A case of malignant pericardial mesothelioma with constrictive pericarditis physiology misdiagnosed as pericardial metastatic cancer. | Korean circulation journal 20110601 |
| A retrospective study of first-line combination chemotherapy in advanced colorectal cancer: a Korean single-center experience. | Cancer research and treatment : official journal of Korean Cancer Association 20110601 |
| Predictive value of in vitro adenosine triphosphate-based chemotherapy response assay in advanced gastric cancer patients who received oral 5-Fluorouracil after curative resection. | Cancer research and treatment : official journal of Korean Cancer Association 20110601 |
| Are Mutations of the EGFR Gene Promising Predictive Markers for Anti-EGFR mAbs in Colorectal Carcinomas? | Journal of the Korean Society of Coloproctology 20110601 |
| Epidermal growth factor receptor mutations in colorectal cancer patients. | Journal of the Korean Society of Coloproctology 20110601 |
| Adjuvant Chemotherapy Using the FOLFOX Regimen in Colon Cancer. | Journal of the Korean Society of Coloproctology 20110601 |
| A phase I study of the chinese herbal medicine PHY906 as a modulator of irinotecan-based chemotherapy in patients with advanced colorectal cancer. | Clinical colorectal cancer 20110601 |
| Emerging therapies in pancreas cancer. | Journal of gastrointestinal oncology 20110601 |
| Epidermal growth factor receptor (EGFR) gene promoter methylation and cetuximab treatment in colorectal cancer patients. | British journal of cancer 20110524 |
| Chemotherapy options in elderly and frail patients with metastatic colorectal cancer (MRC FOCUS2): an open-label, randomised factorial trial. | Lancet (London, England) 20110521 |
| Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: updated analysis of overall survival according to tumor KRAS and BRAF mutation status. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110520 |
| Use of irinotecan for treatment of small cell carcinoma of the prostate. | The Prostate 20110515 |
| Antitumor efficacy of PKI-587, a highly potent dual PI3K/mTOR kinase inhibitor. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110515 |
| Humanized anti-Trop-2 IgG-SN-38 conjugate for effective treatment of diverse epithelial cancers: preclinical studies in human cancer xenograft models and monkeys. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110515 |
| A phase 2 study of irinotecan, cisplatin, and simvastatin for untreated extensive-disease small cell lung cancer. | Cancer 20110515 |
| FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. | The New England journal of medicine 20110512 |
| Involvement of Flt-1 (VEGF receptor-1) in cancer and preeclampsia. | Proceedings of the Japan Academy. Series B, Physical and biological sciences 20110511 |
| Ascorbate exerts anti-proliferative effects through cell cycle inhibition and sensitizes tumor cells towards cytostatic drugs. | Cancer chemotherapy and pharmacology 20110501 |
| A new schedule of fotemustine in temozolomide-pretreated patients with relapsing glioblastoma. | Journal of neuro-oncology 20110501 |
| Phase II study of dose-intense chemotherapy with sequential topoisomerase-targeting regimens with irinotecan/oxaliplatin followed by etoposide/carboplatin in chemotherapy naive patients with extensive small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20110501 |
| Intermittent versus continuous chemotherapy in advanced colorectal cancer: a randomised 'GISCAD' trial. | Annals of oncology : official journal of the European Society for Medical Oncology 20110501 |
| Bevacizumab-induced nasal septal perforation: incidence of symptomatic, confirmed event(s) in colorectal cancer patients. | Acta oncologica (Stockholm, Sweden) 20110501 |
| Early magnesium modifications as a surrogate marker of efficacy of cetuximab-based anticancer treatment in KRAS wild-type advanced colorectal cancer patients. | Annals of oncology : official journal of the European Society for Medical Oncology 20110501 |
| Antiangiogenic tyrosine kinase inhibition related gastrointestinal perforations: a case report and literature review. | Angiogenesis 20110501 |
| Two or three year disease-free survival (DFS) as a primary end-point in stage III adjuvant colon cancer trials with fluoropyrimidines with or without oxaliplatin or irinotecan: data from 12,676 patients from MOSAIC, X-ACT, PETACC-3, C-06, C-07 and C89803. | European journal of cancer (Oxford, England : 1990) 20110501 |
| Docetaxel and irinotecan as second-line therapy for advanced oesophagogastric cancer. | European journal of cancer (Oxford, England : 1990) 20110501 |
| Do pharmacokinetic polymorphisms explain treatment failure in high-risk patients with neuroblastoma? | European journal of clinical pharmacology 20110501 |
| Lapatinib plus trastuzumab for a patient with heavily pre-treated gastric cancer that progressed after trastuzumab. | Japanese journal of clinical oncology 20110501 |
| Anti-stromal therapy with imatinib inhibits growth and metastasis of gastric carcinoma in an orthotopic nude mouse model. | International journal of cancer 20110501 |
| Genz-644282, a novel non-camptothecin topoisomerase I inhibitor for cancer treatment. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110501 |
| An algorithm for chemotherapy treatment of recurrent glioma patients after temozolomide failure in the general oncology setting. | Cancer chemotherapy and pharmacology 20110501 |
| Antiangiogenic agents in combination with chemotherapy in patients with advanced non-small cell lung cancer. | Cancer investigation 20110501 |
| Bevacizumab in combination with cetuximab and irinotecan after failure of cetuximab and irinotecan in patients with metastatic colorectal cancer. | Acta oncologica (Stockholm, Sweden) 20110501 |
| A modified shortened administration schedule for neoadjuvant chemotherapy with irinotecan and cisplatin in locally advanced cervical cancer. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20110501 |
| [A resected case of advanced gastric cancer with multiple liver metastasis successfully treated by preoperative and postoperative S-1/CPT-11 combination chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110501 |
| [Successful optimal debulking surgery following chemotherapy combined with irinotecan hydrochloride and cisplatin for advanced clear cell carcinoma of the ovary]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110501 |
| Bevacizumab in first-line therapy of metastatic colorectal cancer: a retrospective comparison of FOLFIRI and XELIRI. | Anticancer research 20110501 |
| A phase II study of carboplatin and irinotecan in extensive stage small-cell lung cancer. | Clinical lung cancer 20110501 |
| Sex and dosing-time dependencies in irinotecan-induced circadian disruption. | Chronobiology international 20110501 |
| Genetic variation in genes involved in folate and drug metabolism in a south Indian population. | Indian journal of human genetics 20110501 |
| Characteristics and outcomes of patients with advanced gastric cancer who declined to participate in a randomized clinical chemotherapy trial. | Journal of oncology practice 20110501 |
| DNA damage persistence as determinant of tumor sensitivity to the combination of Topo I inhibitors and telomere-targeting agents. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110415 |
| Chemotherapy plus percutaneous radiofrequency ablation in patients with inoperable colorectal liver metastases. | World journal of gastrointestinal oncology 20110415 |
| Structural simplification of bioactive natural products with multicomponent synthesis. 3. Fused uracil-containing heterocycles as novel topoisomerase-targeting agents. | Journal of medicinal chemistry 20110414 |
| Cetuximab plus irinotecan in pretreated metastatic colorectal cancer patients: the ELSIE study. | World journal of gastroenterology 20110414 |
| Pharmacodynamic and pharmacogenetic angiogenesis-related markers of first-line FOLFOXIRI plus bevacizumab schedule in metastatic colorectal cancer. | British journal of cancer 20110412 |
| Chronic exposure of colorectal cancer cells to bevacizumab promotes compensatory pathways that mediate tumour cell migration. | British journal of cancer 20110412 |
| Early evaluation of tumoral response to antiangiogenic therapy by arterial spin labeling perfusion magnetic resonance imaging and susceptibility weighted imaging in a patient with recurrent glioblastoma receiving bevacizumab. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110410 |
| Few positives for triple-negative breast cancer. | Journal of the National Cancer Institute 20110406 |
| Octreotide-targeted liposomes loaded with CPT-11 enhanced cytotoxicity for the treatment of medullary thyroid carcinoma. | Molecular pharmaceutics 20110404 |
| A model of primary culture of colorectal cancer and liver metastasis to predict chemosensitivity. | The Journal of surgical research 20110401 |
| Cellular pharmacology of multi- and duplex drugs consisting of ethynylcytidine and 5-fluoro-2'-deoxyuridine. | Investigational new drugs 20110401 |
| Phase II study of S-1, a novel oral fluoropyrimidine, and biweekly administration of docetaxel for previously treated advanced non-small-cell lung cancer. | Cancer chemotherapy and pharmacology 20110401 |
| BACPTDP: a water-soluble camptothecin pro-drug with enhanced activity in hypoxic/acidic tumors. | Cancer chemotherapy and pharmacology 20110401 |
| Graft-vs-tumor effect in patients with advanced nasopharyngeal cancer treated with nonmyeloablative allogeneic PBSC transplantation. | Bone marrow transplantation 20110401 |
| Dietary glycine protects from chemotherapy-induced hepatotoxicity. | Amino acids 20110401 |
| Two doses of NGR-hTNF in combination with capecitabine plus oxaliplatin in colorectal cancer patients failing standard therapies. | Annals of oncology : official journal of the European Society for Medical Oncology 20110401 |
| Phase II study of a triplet regimen of S-1 combined with irinotecan and oxaliplatin in patients with metastatic gastric cancer: clinical and pharmacogenetic results. | Annals of oncology : official journal of the European Society for Medical Oncology 20110401 |
| Serum matrilysin correlates with poor survival independently of KRAS and BRAF status in refractory advanced colorectal cancer patients treated with irinotecan plus cetuximab. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20110401 |
| ADC histograms predict response to anti-angiogenic therapy in patients with recurrent high-grade glioma. | Neuroradiology 20110401 |
| Human biodistribution and radiation dosimetry of novel PET probes targeting the deoxyribonucleoside salvage pathway. | European journal of nuclear medicine and molecular imaging 20110401 |
| Irinotecan and radiosensitization in rectal cancer. | Anti-cancer drugs 20110401 |
| The role of the transition metal copper and the ionophore A23187 in the development of Irinophore C™. | Pharmaceutical research 20110401 |
| Infratentorial brain metastases of pediatric non-epithelial malignant tumors: three case reports. | Brain tumor pathology 20110401 |
| Effect of omeprazole on the pharmacokinetics and toxicities of irinotecan in cancer patients: a prospective cross-over drug-drug interaction study. | European journal of cancer (Oxford, England : 1990) 20110401 |
| Normalization of T cell receptor repertoire diversity in patients with advanced colorectal cancer who responded to chemotherapy. | Cancer science 20110401 |
| Long-term survival in a patient with small-cell lung cancer undergoing hemodialysis who received multiple courses of chemotherapy. | Japanese journal of clinical oncology 20110401 |
| R1 resection for aggressive or advanced colorectal liver metastases is justified in combination with effective prehepatectomy chemotherapy. | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20110401 |
| The dietary flavonoid apigenin enhances the activities of the anti-metastatic protein CD26 on human colon carcinoma cells. | Clinical & experimental metastasis 20110401 |
| Prospective phase II study of FOLFIRI for mCRC in Japan, including the analysis of UGT1A1 28/6 polymorphisms. | Japanese journal of clinical oncology 20110401 |
| Retrospective cohort study on the safety and efficacy of bevacizumab with chemotherapy for metastatic colorectal cancer patients: the HGCSG0801 study. | Japanese journal of clinical oncology 20110401 |
| Barking up the wrong genome--we are not alone. | Journal of clinical pharmacy and therapeutics 20110401 |
| Irinotecan and bevacizumab in recurrent glioblastoma multiforme. | Expert opinion on pharmacotherapy 20110401 |
| Second-line chemotherapy with fluorouracil, leucovorin, and irinotecan (FOLFIRI regimen) in patients with advanced small bowel adenocarcinoma after failure of first-line platinum-based chemotherapy: a multicenter AGEO study. | Cancer 20110401 |
| Cytotoxic T lymphocytes efficiently recognize human colon cancer stem-like cells. | The American journal of pathology 20110401 |
| Primary neuroendocrine carcinoma of the hypopharynx: a case report. | Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20110401 |
| [A case of recurrent gastric cancer with lymph node metastasis successfully treated by CPT-11/CDDP therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110401 |
| [A case report of primary duodenal adenocarcinoma responding to chemotherapy with S-1 and irinotecan]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110401 |
| [Two cases of advanced colorectal cancer which demonstrated the reversibility of oxaliplatin-mediated increase in splenic volume]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110401 |
| Second-line therapy for small-cell lung cancer. | Expert review of anticancer therapy 20110401 |
| Acneiform eruption following molecular targeted chemotherapy. | Internal medicine journal 20110401 |
| APEX microarray panel for genotyping polymorphisms in cancer chemotherapy and estimation frequencies in a Slovak population. | Pharmacogenomics 20110401 |
| [Comparison between the effects of irinotecan or oxaliplatin combined with capecitabine in the treatment of advanced gastric cancer]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20110401 |
| The use of convection-enhanced delivery with liposomal toxins in neurooncology. | Toxins 20110401 |
| [Chemotherapy for advanced colorectal cancer]. | Nihon rinsho. Japanese journal of clinical medicine 20110401 |
| [Importance and practice of UGT1A1 polymorphisms]. | Nihon rinsho. Japanese journal of clinical medicine 20110401 |
| [Development of oral drugs in the standard therapy for metastatic colorectal cancer patients]. | Nihon rinsho. Japanese journal of clinical medicine 20110401 |
| [Treatment with CPT-11 based on the UGT1A1 genetic polymorphism]. | Nihon rinsho. Japanese journal of clinical medicine 20110401 |
| Phylogenetic discordance of human and canine carcinoembryonic antigen (CEA, CEACAM) families, but striking identity of the CEA receptors will impact comparative oncology studies. | PLoS currents 20110331 |
| G3.5 PAMAM dendrimers enhance transepithelial transport of SN38 while minimizing gastrointestinal toxicity. | Journal of controlled release : official journal of the Controlled Release Society 20110330 |
| Advanced small cell carcinoma of the uterine cervix treated by neoadjuvant chemotherapy with irinotecan and cisplatin followed by radical surgery. | Rare tumors 20110330 |
| CYP2A6 and ERCC1 polymorphisms correlate with efficacy of S-1 plus cisplatin in metastatic gastric cancer patients. | British journal of cancer 20110329 |
| FOLFOX6 and bevacizumab in non-optimally resectable liver metastases from colorectal cancer. | British journal of cancer 20110329 |
| Clinical reports of pulmonary metastasectomy for colorectal cancer: a citation network analysis. | British journal of cancer 20110329 |
| A chemically modified antibody mediates complete eradication of tumours by selective disruption of tumour blood vessels. | British journal of cancer 20110329 |
| Lipopolysaccharide down-regulates carbolesterases 1 and 2 and reduces hydrolysis activity in vitro and in vivo via p38MAPK-NF-κB pathway. | Toxicology letters 20110325 |
| 14-Aminocamptothecins: their synthesis, preclinical activity, and potential use for cancer treatment. | Journal of medicinal chemistry 20110324 |
| Preclinical and clinical studies of NK012, an SN-38-incorporating polymeric micelles, which is designed based on EPR effect. | Advanced drug delivery reviews 20110318 |
| Preoperative chemoradiation with irinotecan and capecitabine in patients with locally advanced resectable rectal cancer: long-term results of a Phase II study. | International journal of radiation oncology, biology, physics 20110315 |
| Characterization, blood profile and biodistribution properties of surface modified PLGA nanoparticles of SN-38. | International journal of pharmaceutics 20110315 |
| KRAS mutation analysis: a comparison between primary tumours and matched liver metastases in 305 colorectal cancer patients. | British journal of cancer 20110315 |
| Preoperative chemoradiotherapy using concurrent capecitabine and irinotecan in magnetic resonance imaging-defined locally advanced rectal cancer: impact on long-term clinical outcomes. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110310 |
| Cetuximab plus capecitabine and irinotecan compared with cetuximab plus capecitabine and oxaliplatin as first-line treatment for patients with metastatic colorectal cancer: AIO KRK-0104--a randomized trial of the German AIO CRC study group. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110310 |
| Three-drug combination regimen in pancreatic cancer treatment: are we there yet? | JOP : Journal of the pancreas 20110309 |
| Treatment for refractory pancreatic cancer. Highlights from the '2011 ASCO Gastrointestinal Cancers Symposium'. San Francisco, CA, USA. January 20-22, 2011. | JOP : Journal of the pancreas 20110309 |
| Cytokeratin expression patterns in multiple infundibulocystic basal cell carcinoma. | Journal of cutaneous pathology 20110301 |
| Development and validation of a prediction model for the risk of developing febrile neutropenia in the first cycle of chemotherapy among elderly patients with breast, lung, colorectal, and prostate cancer. | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20110301 |
| Irinotecan plus carboplatin in patients with extensive-disease small-cell lung cancer. | Medical oncology (Northwood, London, England) 20110301 |
| Effective conversion of irinotecan to SN-38 after intratumoral drug delivery to an intracranial murine glioma model in vivo. Laboratory investigation. | Journal of neurosurgery 20110301 |
| Phase I/II study of irinotecan, UFT and leucovorin with hepatic arterial infusion using 5-FU in colorectal cancer patients with unresectable liver metastases. | Cancer chemotherapy and pharmacology 20110301 |
| Two phase I studies of concurrent radiation therapy with continuous-infusion 5-fluorouracil plus epirubicin, and either cisplatin or irinotecan for locally advanced upper gastrointestinal adenocarcinomas. | Cancer chemotherapy and pharmacology 20110301 |
| Oxaliplatin in combination with liver-specific expression of interleukin 12 reduces the immunosuppressive microenvironment of tumours and eradicates metastatic colorectal cancer in mice. | Gut 20110301 |
| Regenerative nodular hyperplasia of the liver related to chemotherapy: impact on outcome of liver surgery for colorectal metastases. | Annals of surgical oncology 20110301 |
| A Phase II trial of neoadjuvant preoperative chemoradiotherapy with S-1 plus irinotecan and radiation in patients with locally advanced rectal cancer: clinical feasibility and response rate. | International journal of radiation oncology, biology, physics 20110301 |
| High-dose carboplatin-irinotecan-temozolomide: treatment option for neuroblastoma resistant to topotecan. | Pediatric blood & cancer 20110301 |
| Bevacizumab and irinotecan in the treatment of children with recurrent/refractory medulloblastoma. | Pediatric blood & cancer 20110301 |
| Toxicity, response rates and survival outcomes of induction cisplatin and irinotecan followed by concurrent cisplatin, irinotecan and radiotherapy for locally advanced esophageal cancer. | Japanese journal of clinical oncology 20110301 |
| A phase I study of S-1 and irinotecan combination therapy in previously treated advanced non-small cell lung cancer patients. | Cancer chemotherapy and pharmacology 20110301 |
| Anatomical versus nonanatomical resection of colorectal liver metastases: is there a difference in surgical and oncological outcome? | World journal of surgery 20110301 |
| Effect of kaempferol on lipid peroxidation and antioxidant status in 1,2-dimethyl hydrazine induced colorectal carcinoma in rats. | European journal of pharmacology 20110301 |
| Randomized phase II trial of adjuvant hepatic arterial infusion and systemic chemotherapy with or without bevacizumab in patients with resected hepatic metastases from colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110301 |
| Anti-DLL4 inhibits growth and reduces tumor-initiating cell frequency in colorectal tumors with oncogenic KRAS mutations. | Cancer research 20110301 |
| Thymidylate synthase genotype-directed neoadjuvant chemoradiation for patients with rectal adenocarcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110301 |
| Improvements in population-based survival of patients presenting with metastatic rectal cancer in the south of the Netherlands, 1992-2008. | Clinical & experimental metastasis 20110301 |
| The acridone derivative MBLI-87 sensitizes breast cancer resistance protein-expressing xenografts to irinotecan. | European journal of cancer (Oxford, England : 1990) 20110301 |
| Specifically targeting angiopoietin-2 inhibits angiogenesis, Tie2-expressing monocyte infiltration, and tumor growth. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110301 |
| Feasibility of EUS-guided injection of irinotecan-loaded microspheres into the swine pancreas. | Gastrointestinal endoscopy 20110301 |
| Impact of bevacizumab on functional recovery and histology of the liver after resection of colorectal metastases. | The British journal of surgery 20110301 |
| The role of radiation in the perioperative treatment of esophagogastric cancer. | Current treatment options in oncology 20110301 |
| Arguments against toxic effects of chemotherapy on liver injury and regeneration in an experimental model of partial hepatectomy. | Liver international : official journal of the International Association for the Study of the Liver 20110301 |
| BRAF mutation is a powerful prognostic factor in advanced and recurrent colorectal cancer. | British journal of cancer 20110301 |
| Targeted therapies for metastatic esophagogastric cancer. | Current treatment options in oncology 20110301 |
| Aurora B kinase inhibitor AZD1152: determinants of action and ability to enhance chemotherapeutics effectiveness in pancreatic and colon cancer. | British journal of cancer 20110301 |
| Prevalence of clinically relevant UGT1A alleles and haplotypes in African populations. | Annals of human genetics 20110301 |
| Capecitabine monotherapy as salvage treatment after failure of chemotherapy containing oxaliplatin and irinotecan in patients with metastatic colorectal cancer. | Asia-Pacific journal of clinical oncology 20110301 |
| Randomized phase III study comparing the efficacy and safety of irinotecan plus S-1 with S-1 alone as first-line treatment for advanced gastric cancer (study GC0301/TOP-002). | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20110301 |
| Spectrofluorimetric determination of SN-38, a promising new anti-tumor agent, in the presence and absence of organized media. | Applied spectroscopy 20110301 |
| Irinotecan is inactive as a first-line treatment, but plays an important part in gastric cancer treatment. | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20110301 |
| The role of reactive oxygen species and autophagy in safingol-induced cell death. | Cell death & disease 20110301 |
| Irinotecan synergistically enhances the antiproliferative and proapoptotic effects of axitinib in vitro and improves its anticancer activity in vivo. | Neoplasia (New York, N.Y.) 20110301 |
| Recent advances in anti-angiogenic therapy of cancer. | Oncotarget 20110301 |
| [A case of spindle cell carcinoma of the breast, in which irinotecan was effective against respiratory failure due to pulmonary metastases]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110301 |
| [Palliative anti-cancer chemotherapy is safely executable in a hemodialytic patient with unresectable advanced gastric cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110301 |
| [A case of drug-induced interstitial pneumonia caused by S-1 and CPT-11 combination therapy for advanced colon cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110301 |
| Efficacy and safety of hepatic arterial infusion of fluorouracil with leucovorin as salvage treatment for refractory liver metastases from colorectal cancer. | The Korean journal of internal medicine 20110301 |
| Vascular co-option in lung cancer metastatic to the eye after treatment with bevacizumab. | Journal of ophthalmic inflammation and infection 20110301 |
| The mind-body-microbial continuum. | Dialogues in clinical neuroscience 20110301 |
| Does erlotinib restore chemosensitivity to chemotherapy in pancreatic cancer? A case series. | Anticancer research 20110301 |
| Safe use of FOLFOX in two patients with metastatic colorectal carcinoma and severe hepatic dysfunction. | Clinical colorectal cancer 20110301 |
| Efficacy and tolerability of biweekly bevacizumab, irinotecan, folinic acid and fluorouracil intravenous bolus (BIFF Regimen) in patients with metastatic colorectal cancer: the southern Italy cooperative oncology group experience. | Clinical colorectal cancer 20110301 |
| Role of multidrug resistance protein 2 (MRP2) in chemoresistance and clinical outcome in oesophageal squamous cell carcinoma. | British journal of cancer 20110215 |
| ALKBH3, a human AlkB homologue, contributes to cell survival in human non-small-cell lung cancer. | British journal of cancer 20110215 |
| Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease. | British journal of cancer 20110215 |
| Small molecule kinase inhibitor screen identifies polo-like kinase 1 as a target for neuroblastoma tumor-initiating cells. | Cancer research 20110215 |
| Hypertension and overall survival in metastatic colorectal cancer patients treated with bevacizumab-containing chemotherapy. | British journal of cancer 20110215 |
| Phase II study of S-1 combined with oxaliplatin as therapy for patients with metastatic biliary tract cancer: influence of the CYP2A6 polymorphism on pharmacokinetics and clinical activity. | British journal of cancer 20110215 |
| Protein kinase CK2 is a central regulator of topoisomerase I hyperphosphorylation and camptothecin sensitivity in cancer cell lines. | Biochemistry 20110208 |
| Microarrays for the scalable production of metabolically relevant tumour spheroids: a tool for modulating chemosensitivity traits. | Lab on a chip 20110207 |
| Pharmacogenetics of telatinib, a VEGFR-2 and VEGFR-3 tyrosine kinase inhibitor, used in patients with solid tumors. | Investigational new drugs 20110201 |
| Prediction of irinotecan and 5-fluorouracil toxicity and response in patients with advanced colorectal cancer. | The pharmacogenomics journal 20110201 |
| Cetuximab and circadian chronomodulated chemotherapy as salvage treatment for metastatic colorectal cancer (mCRC): safety, efficacy and improved secondary surgical resectability. | Cancer chemotherapy and pharmacology 20110201 |
| Acute thrombocytopenia: an unusual complication occurring after drug-eluting microspheres transcatheter hepatic chemoembolization. | Cardiovascular and interventional radiology 20110201 |
| Precision hepatic arterial irinotecan therapy in the treatment of unresectable intrahepatic cholangiocellular carcinoma: optimal tolerance and prolonged overall survival. | Annals of surgical oncology 20110201 |
| The importance of evaluation of DNA amplificability in KRAS mutation testing with dideoxy sequencing using formalin-fixed and paraffin-embedded colorectal cancer tissues. | Japanese journal of clinical oncology 20110201 |
| Phase I/II study of FOLFIRI in Japanese patients with advanced colorectal cancer. | Japanese journal of clinical oncology 20110201 |
| Delayed elimination of SN-38 in cancer patients with severe renal failure. | Drug metabolism and disposition: the biological fate of chemicals 20110201 |
| Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model. | Drug metabolism and disposition: the biological fate of chemicals 20110201 |
| Optimizing the efficacy of first-line chemotherapy plus bevacizumab in metastatic colorectal cancer: analysis of multiple methods. | BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20110201 |
| Are we turning to more than a first line treatment of metastatic colorectal cancer with high dose irinotecan?: A monocentric institution safety analysis of 46 patients. | Clinics and research in hepatology and gastroenterology 20110201 |
| Isolation and characterization of gemcitabine-resistant human non-small cell lung cancer A549 cells. | International journal of oncology 20110201 |
| Targeting the p38 MAPK pathway inhibits irinotecan resistance in colon adenocarcinoma. | Cancer research 20110201 |
| A prospective study of chemotherapy-induced febrile neutropenia in the South West London Cancer Network. Interpretation of study results in light of NCAG/NCEPOD findings. | British journal of cancer 20110201 |
| Predictive value of VEGF gene polymorphisms for metastatic colorectal cancer patients receiving first-line treatment including fluorouracil, irinotecan, and bevacizumab. | International journal of colorectal disease 20110201 |
| Health-related quality of life and colorectal cancer-specific symptoms in patients with chemotherapy-refractory metastatic disease treated with panitumumab. | International journal of colorectal disease 20110201 |
| Clinical significance of tumor suppressor PTEN in colorectal carcinoma. | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20110201 |
| Metronomic irinotecan chemotherapy combined with ultrasound irradiation for a human uterine sarcoma xenograft. | Cancer science 20110201 |
| Tumour gene expression predicts response to cetuximab in patients with KRAS wild-type metastatic colorectal cancer. | British journal of cancer 20110201 |
| DC Bead embolic drug-eluting bead: clinical application in the locoregional treatment of tumours. | Expert opinion on drug delivery 20110201 |
| Changing management and survival in patients with stage IV colorectal cancer. | Diseases of the colon and rectum 20110201 |
| Bleeding events in bevacizumab-treated cancer patients who received full-dose anticoagulation and remained on study. | British journal of cancer 20110201 |
| Complement and correction for meta-analysis of patients with extensive-stage small cell lung cancer managed with irinotecan/cisplatin versus etoposide/cisplatin as first-line chemotherapy. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110201 |
| A Blm-Recql5 partnership in replication stress response. | Journal of molecular cell biology 20110201 |
| Patterns of progression in patients with recurrent glioblastoma treated with bevacizumab. | Neurology 20110201 |
| [Pharmacogenomic research for avoiding adverse reactions by anti-cancer drugs]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110201 |
| A robust approach to enhance tumor-selective accumulation of nanoparticles. | Oncotarget 20110201 |
| Clinical impact of tumor regression grade after preoperative chemoradiation for locally advanced rectal cancer: subset analyses in lymph node negative patients. | Journal of the Korean Society of Coloproctology 20110201 |
| Adjuvant chemotherapy for localised colon cancer. Fluorouracil + folinic acid for node-positive, non-metastatic disease. | Prescrire international 20110201 |
| Anticancer and anti-inflammatory activities of shallot (Allium ascalonicum) extract. | Archives of medical science : AMS 20110201 |
| Systematic review on infusion reactions associated with chemotherapies and monoclonal antibodies for metastatic colorectal cancer. | Current clinical pharmacology 20110201 |
| Phase I trial of docetaxel, cisplatin and concurrent radical radiotherapy in locally advanced oesophageal cancer. | British journal of cancer 20110118 |
| Single agent and combination studies of pralatrexate and molecular correlates of sensitivity. | British journal of cancer 20110118 |
| 3-Arylisoquinolines as novel topoisomerase I inhibitors. | Bioorganic & medicinal chemistry 20110115 |
| Phase II study of irinotecan and temozolomide in children with relapsed or refractory neuroblastoma: a Children's Oncology Group study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110110 |
| Translational proteomics: what can you do for true patients? | Journal of proteome research 20110107 |
| Randomized trial of two induction chemotherapy regimens in metastatic colorectal cancer: an updated analysis. | Journal of the National Cancer Institute 20110105 |
| Toxicity associated with capecitabine plus oxaliplatin in colorectal cancer before and after an institutional policy of capecitabine dose reduction. | British journal of cancer 20110104 |
| Efficacy of goshajinkigan for peripheral neurotoxicity of oxaliplatin in patients with advanced or recurrent colorectal cancer. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
| Phase II trial of induction irinotecan-cisplatin followed by concurrent irinotecan-cisplatin and radiotherapy for unresectable, locally advanced gastric and oesophageal-gastric junction adenocarcinoma. | Cancer chemotherapy and pharmacology 20110101 |
| Sequential chemotherapy with dose-dense docetaxel, cisplatin, folinic acid and 5-fluorouracil (TCF-dd) followed by combination of oxaliplatin, folinic acid, 5-fluorouracil and irinotecan (COFFI) in metastatic gastric cancer: results of a phase II trial. | Cancer chemotherapy and pharmacology 20110101 |
| Phase I study of intraperitoneal irinotecan in patients with gastric adenocarcinoma with peritoneal seeding. | Cancer chemotherapy and pharmacology 20110101 |
| Phase II study of FOLFIRI regimen in patients with advanced colorectal cancer refractory to fluoropyrimidine and oxaliplatin. | Cancer chemotherapy and pharmacology 20110101 |
| Hyaluronan-Irinotecan improves progression-free survival in 5-fluorouracil refractory patients with metastatic colorectal cancer: a randomized phase II trial. | Cancer chemotherapy and pharmacology 20110101 |
| Streptomycin alleviates irinotecan-induced delayed-onset diarrhea in rats by a mechanism other than inhibition of β-glucuronidase activity in intestinal lumen. | Cancer chemotherapy and pharmacology 20110101 |
| Evolution of laparoscopic left lateral sectionectomy without the Pringle maneuver: through resection of benign and malignant tumors to living liver donation. | Surgical endoscopy 20110101 |
| Multiple primary cranio-spinal tumours in a 13-year-old female with neurofibromatosis type 2 management strategy. | Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20110101 |
| Effects of methimazole on the elimination of irinotecan. | Cancer chemotherapy and pharmacology 20110101 |
| In vitro drug responses in primary and metastatic colorectal cancers. | Scandinavian journal of gastroenterology 20110101 |
| Hepatic intra-arterial injection of drug-eluting bead, irinotecan (DEBIRI) in unresectable colorectal liver metastases refractory to systemic chemotherapy: results of multi-institutional study. | Annals of surgical oncology 20110101 |
| A phase II study of cisplatin and irinotecan as induction chemotherapy followed by concomitant thoracic radiotherapy with weekly low-dose irinotecan in unresectable, stage III, non-small cell lung cancer: JCOG 9706. | Japanese journal of clinical oncology 20110101 |
| The small-molecule tyrosine kinase inhibitor nilotinib is a potent noncompetitive inhibitor of the SN-38 glucuronidation by human UGT1A1. | Cancer chemotherapy and pharmacology 20110101 |
| Pharmacogenetic tests in cancer chemotherapy: what physicians should know for clinical application. | The Journal of pathology 20110101 |
| Organ-specific carboxylesterase profiling identifies the small intestine and kidney as major contributors of activation of the anticancer prodrug CPT-11. | Biochemical pharmacology 20110101 |
| UDP-glucuronosyltransferase 1A6 overexpression in breast cancer cells resistant to methotrexate. | Biochemical pharmacology 20110101 |
| 18Fluoro-deoxy-glucose positron emission tomography in assessing tumor response to preoperative chemoradiation therapy for locally advanced rectal cancer. | Journal of surgical oncology 20110101 |
| High-dose cyclophosphamide-irinotecan-vincristine for primary refractory neuroblastoma. | European journal of cancer (Oxford, England : 1990) 20110101 |
| Phase III trial of irinotecan plus infusional 5-fluorouracil/folinic acid versus irinotecan plus oxaliplatin as first-line treatment of advanced colorectal cancer. | European journal of cancer (Oxford, England : 1990) 20110101 |
| Targeting the mechanisms of resistance to chemotherapy and radiotherapy with the cancer stem cell hypothesis. | Journal of oncology 20110101 |
| FOLFIRINOX: a new standard treatment for advanced pancreatic cancer? | The Lancet. Oncology 20110101 |
| Targeted Therapy of Ewing's Sarcoma. | Sarcoma 20110101 |
| Anti-VEGF therapy in breast and lung mouse models of cancers. | Journal of biomedicine & biotechnology 20110101 |
| Response as a predictor of survival in patients with recurrent glioblastoma treated with bevacizumab. | Neuro-oncology 20110101 |
| Treatment patterns and metastasectomy among mCRC patients receiving chemotherapy and biologics. | Current medical research and opinion 20110101 |
| Monoclonal antibodies in neuro-oncology: Getting past the blood-brain barrier. | mAbs 20110101 |
| Randomized phase II trial of irinotecan with paclitaxel or gemcitabine for non-small cell lung cancer: association of UGT1A1*6 and UGT1A1*27 with severe neutropenia. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110101 |
| Comparison of nedaplatin and irinotecan for patients with squamous and nonsquamous cell carcinoma of the lung: meta-analysis of four trials. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110101 |
| Current therapeutic approaches in metastatic and recurrent ewing sarcoma. | Sarcoma 20110101 |
| A preliminary report of a Phase II study of folinic acid, 5-fluorouracil, irinotecan (FOLFIRI) plus sunitinib with toxicity, efficacy, pharmacokinetics, biomarker, imaging data in patients with colorectal cancer with liver metastases as 1st line treatment. | International journal of clinical pharmacology and therapeutics 20110101 |
| [Oncosurgical strategies for metastatic liver cancer]. | Cirugia espanola 20110101 |
| Targeted therapies in cancer - challenges and chances offered by newly developed techniques for protein analysis in clinical tissues. | Journal of Cancer 20110101 |
| Targeting angiogenesis in childhood sarcomas. | Sarcoma 20110101 |
| The role of HER-3 expression in the prediction of clinical outcome for advanced colorectal cancer patients receiving irinotecan and cetuximab. | The oncologist 20110101 |
| Antiangiogenic agents in the treatment of recurrent or newly diagnosed glioblastoma: analysis of single-agent and combined modality approaches. | Radiation oncology (London, England) 20110101 |
| Smac mimetic-derived augmentation of chemotherapeutic response in experimental pancreatic cancer. | BMC cancer 20110101 |
| Exploiting the complexity of the genome and transcriptome using pharmacogenomics towards personalized medicine. | Genome biology 20110101 |
| Receptor tyrosine kinases as therapeutic targets in rhabdomyosarcoma. | Sarcoma 20110101 |
| Pharmacogenetic tailoring of irinotecan-based first-line chemotherapy in metastatic colorectal cancer: results of a pilot study. | Anticancer research 20110101 |
| A randomized phase III trial of adjuvant chemotherapy with irinotecan, leucovorin and fluorouracil versus leucovorin and fluorouracil for stage II and III colon cancer: a Hellenic Cooperative Oncology Group study. | BMC medicine 20110101 |
| Selection of housekeeping genes for gene expression studies in a rat model of irinotecan-induced mucositis. | Chemotherapy 20110101 |
| Contributions made by CDC25 phosphatases to proliferation of intestinal epithelial stem and progenitor cells. | PloS one 20110101 |
| Impact of KRAS, BRAF, PIK3CA mutations, PTEN, AREG, EREG expression and skin rash in ≥ 2 line cetuximab-based therapy of colorectal cancer patients. | PloS one 20110101 |
| Inhibition of angiogenesis and suppression of colorectal cancer metastatic to the liver using the Sleeping Beauty Transposon System. | Molecular cancer 20110101 |
| DNA polymerase β as a novel target for chemotherapeutic intervention of colorectal cancer. | PloS one 20110101 |
| Bioinformatic analyses identifies novel protein-coding pharmacogenomic markers associated with paclitaxel sensitivity in NCI60 cancer cell lines. | BMC medical genomics 20110101 |
| A comparison of mortality and costs associated with FOLFOX versus FOLFIRI in stage IV colorectal cancer. | Journal of medical economics 20110101 |
| Phase II clinical study of the combination chemotherapy regimen of irinotecan plus oral etoposide for the treatment of recurrent ovarian cancer (Tohoku Gynecologic Cancer Unit 101 Group Study). | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20110101 |
| Involvement of promoter methylation in the regulation of Pregnane X receptor in colon cancer cells. | BMC cancer 20110101 |
| The use of endophytes to obtain bioactive compounds and their application in biotransformation process. | Biotechnology research international 20110101 |
| Brain microischemic phenomena in a woman receiving bevacizumab treatment: a case report. | Journal of medical case reports 20110101 |
| A role of 18F-fluorodeoxyglucose positron emission/computed tomography in a strategy for abdominal wall metastasis of colorectal mucinous adenocarcinoma developed after laparoscopic surgery. | World journal of surgical oncology 20110101 |
| [Analysis of gene expression patterns in an irinotecan-resistance colon cancer cell by cDNA microarray]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20110101 |
| [A case of drug-induced lung injury associated with chemotherapy (FOLFOX6, FOLFIRI, Bevacizumab) for an advanced colon cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110101 |
| Intravenous ascorbic acid to prevent and treat cancer-associated sepsis? | Journal of translational medicine 20110101 |
| Bevacizumab in the treatment of ovarian cancer. | Biologics : targets & therapy 20110101 |
| Integrated mutation, copy number and expression profiling in resectable non-small cell lung cancer. | BMC cancer 20110101 |
| Oxaliplatin long-circulating liposomes improved therapeutic index of colorectal carcinoma. | BMC biotechnology 20110101 |
| MicroRNA Expression in Selected Carcinomas of the Gastrointestinal Tract. | Pathology research international 20110101 |
| EGFR Signaling in Colorectal Carcinoma. | Pathology research international 20110101 |
| Clinical and pathological implications of concurrent autoimmune thyroid disorders and papillary thyroid cancer. | Journal of thyroid research 20110101 |
| From antiangiogenesis to hypoxia: current research and future directions. | Cancer management and research 20110101 |
| Common secondary causes of resistant hypertension and rational for treatment. | International journal of hypertension 20110101 |
| Impact of KRAS Mutations on Management of Colorectal Carcinoma. | Pathology research international 20110101 |
| EGFR related mutational status and association to clinical outcome of third-line cetuximab-irinotecan in metastatic colorectal cancer. | BMC cancer 20110101 |
| A meta-analysis of gemcitabine containing chemotherapy for locally advanced and metastatic pancreatic adenocarcinoma. | Journal of hematology & oncology 20110101 |
| Irinotecan-cetuximab-bevacizumab as a salvage treatment in heavily pretreated metastatic colorectal cancer patients: a retrospective observational study. | Chemotherapy 20110101 |
| Risk factors for oxaliplatin-induced hypersensitivity reactions in Japanese patients with advanced colorectal cancer. | International journal of medical sciences 20110101 |
| HDAC inhibition decreases the expression of EGFR in colorectal cancer cells. | PloS one 20110101 |
| A fully integrated and automated detection system for single nucleotide polymorphisms of UGT1A1 and CYP2C19. | Oncology research 20110101 |
| An effective personalized approach to a rare tumor: prolonged survival in metastatic pancreatic acinar cell carcinoma based on genetic analysis and cell line development. | Journal of Cancer 20110101 |
| A retrospective review of the frequency and nature of acute hypersensitivity reactions at a medium-sized infusion center: comparison to reported values and inconsistencies found in literature. | Journal of Cancer 20110101 |
| Vascular normalization in orthotopic glioblastoma following intravenous treatment with lipid-based nanoparticulate formulations of irinotecan (Irinophore C™), doxorubicin (Caelyx®) or vincristine. | BMC cancer 20110101 |
| Does age matter? - A MRI study on peritumoral edema in newly diagnosed primary glioblastoma. | BMC cancer 20110101 |
| Inhibition of nuclear factor kappa-B signaling reduces growth in medulloblastoma in vivo. | BMC cancer 20110101 |
| Targeted morphoproteomic profiling of Ewing's sarcoma treated with insulin-like growth factor 1 receptor (IGF1R) inhibitors: response/resistance signatures. | PloS one 20110101 |
| Promising cytotoxic activity profile of fermented wheat germ extract (Avemar®) in human cancer cell lines. | Journal of experimental & clinical cancer research : CR 20110101 |
| Quantitative in vivo assessment of radiation injury of the liver using Gd-EOB-DTPA enhanced MRI: tolerance dose of small liver volumes. | Radiation oncology (London, England) 20110101 |
| Review of the management of relapsed small-cell lung cancer with amrubicin hydrochloride. | Clinical Medicine Insights. Oncology 20110101 |
| Achievement of three year remission with bevacizumab and irinotecan in recurrent glioblastoma multiforme: a case report. | Clinical Medicine Insights. Oncology 20110101 |
| Novel targeted therapeutics: inhibitors of MDM2, ALK and PARP. | Journal of hematology & oncology 20110101 |
| Role of bile salt in regulating Mcl-1 phosphorylation and chemoresistance in hepatocellular carcinoma cells. | Molecular cancer 20110101 |
| A comparison of four fibrosis indexes in chronic HCV: development of new fibrosis-cirrhosis index (FCI). | BMC gastroenterology 20110101 |
| Camptothecin-based regimens for treatment of ewing sarcoma: past studies and future directions. | Sarcoma 20110101 |
| Radiofrequency ablation resulting in left lobe hypertrophy and improved resectability. | Case reports in gastroenterology 20110101 |
| Multimodal assessment of painful peripheral neuropathy induced by chronic oxaliplatin-based chemotherapy in mice. | Molecular pain 20110101 |
| Palliative first-line therapy with weekly high-dose 5-fluorouracil and sodium folinic acid as a 24-hour infusion (AIO regimen) combined with weekly irinotecan in patients with metastatic adenocarcinoma of the stomach or esophagogastric junction followed by secondary metastatic resection after downsizing. | Medical science monitor : international medical journal of experimental and clinical research 20110101 |
| Hepatic arterial infusion chemotherapy for liver metastases from gastric cancer: an analysis in Western patients. | Tumori 20110101 |
| Urinary elimination of coproporphyrins is dependent on ABCC2 polymorphisms and represents a potential biomarker of MRP2 activity in humans. | Journal of biomedicine & biotechnology 20110101 |
| Phase II trial of irinotecan plus nedaplatin (INP) in treating patients with extensive stage small cell lung cancer. | Asian Pacific journal of cancer prevention : APJCP 20110101 |
| PET Imaging of Integrin αVβ3 Expression. | Theranostics 20110101 |
| Analysis of the anti-tumor effect of cetuximab using protein kinetics and mouse xenograft models. | BMC research notes 20110101 |
| Critical appraisal of trastuzumab in treatment of advanced stomach cancer. | Cancer management and research 20110101 |
| Safety and pharmacokinetics of motesanib in combination with panitumumab and gemcitabine-Cisplatin in patients with advanced cancer. | Journal of oncology 20110101 |
| High-dose chemotherapy with autologous hematopoietic stem-cell rescue for pediatric brain tumor patients: a single institution experience from UCLA. | Journal of transplantation 20110101 |
| Interaction of a traditional Chinese Medicine (PHY906) and CPT-11 on the inflammatory process in the tumor microenvironment. | BMC medical genomics 20110101 |
| Interferon-α/β and anti-fibroblast growth factor receptor 1 monoclonal antibody suppress hepatic cancer cells in vitro and in vivo. | PloS one 20110101 |
| Identification and replication of loci involved in camptothecin-induced cytotoxicity using CEPH pedigrees. | PloS one 20110101 |
| Esophageal small-cell carcinoma with syndrome of inappropriate secretion of antidiuretic hormone. | Internal medicine (Tokyo, Japan) 20110101 |
| Genetic variation in DNA-repair pathways and response to radiochemotherapy in esophageal adenocarcinoma: a retrospective cohort study of the Eastern Cooperative Oncology Group. | BMC cancer 20110101 |
| Thymidine Phosphorylase/β-tubulin III expressions predict the response in Chinese advanced gastric cancer patients receiving first-line capecitabine plus paclitaxel. | BMC cancer 20110101 |
| Small invasive colon cancer with systemic metastasis: a case report. | BMC gastroenterology 20110101 |
| Clinical outcomes of chemoradiotherapy for locally recurrent rectal cancer. | Radiation oncology (London, England) 20110101 |
| Panitumumab (vectibix). | AJNR. American journal of neuroradiology 20110101 |
| Prospective phase II trial of gemcitabine in combination with irinotecan as first-line chemotherapy in patients with advanced biliary tract cancer. | Chemotherapy 20110101 |
| Systemic therapy for elderly patients with gastrointestinal cancer. | Clinical Medicine Insights. Oncology 20110101 |
| Bevacizumab for the treatment of recurrent glioblastoma. | Clinical Medicine Insights. Oncology 20110101 |
| Topoisomerase I inhibitor SN-38 effectively attenuates growth of human non-small cell lung cancer cell lines in vitro and in vivo. | Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20110101 |
| Complementary and alternative medicine use in oncology: a questionnaire survey of patients and health care professionals. | BMC cancer 20110101 |
| Platinum agent-induced hypersensitivity reactions: data mining of the public version of the FDA adverse event reporting system, AERS. | International journal of medical sciences 20110101 |
| Concurrence of UGT1A polymorphism and end-stage renal disease leads to severe toxicities of irinotecan in a patient with metastatic colon cancer. | Tumori 20110101 |
| Systemic chemotherapy for treatment of advanced small bowel adenocarcinoma with prognostic factor analysis: retrospective study. | BMC cancer 20110101 |
| Variations in Mre11/Rad50/Nbs1 status and DNA damage-induced S-phase arrest in the cell lines of the NCI60 panel. | BMC cancer 20110101 |
| New Topoisomerase I mutations are associated with resistance to camptothecin. | Molecular cancer 20110101 |
| Minichromosome Maintenance Protein 7 is a potential therapeutic target in human cancer and a novel prognostic marker of non-small cell lung cancer. | Molecular cancer 20110101 |
| Expression of OATP family members in hormone-related cancers: potential markers of progression. | PloS one 20110101 |
| Current developments in the therapy of protozoan infections. | The open medicinal chemistry journal 20110101 |
| Pharmacokinetics of intravitreal bevacizumab (Avastin®) in rabbits. | Clinical ophthalmology (Auckland, N.Z.) 20110101 |
| Calbindin 2 (CALB2) regulates 5-fluorouracil sensitivity in colorectal cancer by modulating the intrinsic apoptotic pathway. | PloS one 20110101 |
| Capecitabine in the management of colorectal cancer. | Cancer management and research 20110101 |
| Efficacy of irinotecan in combination with 5-fluorouracil (FOLFIRI) for metastatic gastric or gastroesophageal junction adenocarcinomas (MGA) treatment. | Clinics and research in hepatology and gastroenterology 20110101 |
| Tumor angiogenesis and vascular patterning: a mathematical model. | PloS one 20110101 |
| Microsatellite instability in pediatric high grade glioma is associated with genomic profile and differential target gene inactivation. | PloS one 20110101 |
| p21(WAF1/CIP1) upregulation through the stress granule-associated protein CUGBP1 confers resistance to bortezomib-mediated apoptosis. | PloS one 20110101 |
| A High Throughput Assay for Discovery of Bacterial β-Glucuronidase Inhibitors. | Current chemical genomics 20110101 |
| Transport processes of radiopharmaceuticals and -modulators. | Radiation oncology (London, England) 20110101 |
| Molecular profile and copy number analysis of sporadic colorectal cancer in Taiwan. | Journal of biomedical science 20110101 |
| Phase II study of combined treatment with irinotecan and S-1 (IRIS) in patients with inoperable or recurrent advanced colorectal cancer (HGCSG0302). | Oncology 20110101 |
| HCV genotype-specific correlation with serum markers: higher predictability for genotype 4a. | Virology journal 20110101 |
| Strain- and sex-dependent circadian changes in abcc2 transporter expression: implications for irinotecan chronotolerance in mouse ileum. | PloS one 20110101 |
| Mitomycin-C in combination with fluoropyrimidines in the treatment of metastatic colorectal cancer after oxaliplatin and irinotecan failure. | Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20110101 |
| Regarding 'Treatment of colorectal cancer with and without bevacizumab: a phase III study'. | Oncology 20110101 |
| Comment on 'Treatment of colorectal cancer with and without bevacizumab: a phase III study'. | Oncology 20110101 |
| Early start of chemotherapy after resection of primary colon cancer with synchronous multiple liver metastases: a case report. | Case reports in oncology 20110101 |
| KRAS mutation detection in paired frozen and Formalin-Fixed Paraffin-Embedded (FFPE) colorectal cancer tissues. | International journal of molecular sciences 20110101 |
| 'Genetic profiling' and ovarian cancer therapy (review). | Molecular medicine reports 20110101 |
| An update on TroVax for the treatment of progressive castration-resistant prostate cancer. | OncoTargets and therapy 20110101 |
| Safety and efficacy of vinorelbine in the treatment of non-small cell lung cancer. | Clinical Medicine Insights. Oncology 20110101 |
| Clinicopathological and prognostic significance of HER-2/neu and VEGF expression in colon carcinomas. | BMC cancer 20110101 |
| Promising molecular targeted therapies in breast cancer. | Indian journal of pharmacology 20110101 |
| Primary mucinous adenocarcinoma of the vermiform appendix with high grade microsatellite instability. | Journal of Cancer 20110101 |
| Expression and prognostic value of circulating angiogenic cytokines in pancreatic cancer. | BMC cancer 20110101 |
| Irinotecan induces steroid and xenobiotic receptor (SXR) signaling to detoxification pathway in colon cancer cells. | Molecular cancer 20110101 |
| Recombinant immunotoxin anti-c-Met/PE38KDEL inhibits proliferation and promotes apoptosis of gastric cancer cells. | Journal of experimental & clinical cancer research : CR 20110101 |
| In Situ intestinal perfusion of irinotecan: application to P-gp mediated drug interaction and introduction of an improved HPLC assay. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20110101 |
| Phase II study of weekly irinotecan plus cisplatin in patients with previously untreated extensive-stage extrapulmonary small cell carcinoma. | Onkologie 20110101 |
| Targeted treatment of recurrent platinum-resistant ovarian cancer: current and emerging therapies. | Cancer management and research 20110101 |
| A Case of High-Grade Neuroendocrine Carcinoma That Improved with Bevacizumab plus Modified FOLFOX6 as the Fourth-Line Chemotherapy. | Case reports in oncology 20110101 |
| Meta-analysis of multiple microarray datasets reveals a common gene signature of metastasis in solid tumors. | BMC medical genomics 20110101 |
| Small cell ovarian cancer in adolescents: report of two cases and review of the literature. | Case reports in medicine 20110101 |
| First-order multivariate calibration applied to the simultaneous fluorometric determination of the anticancer agents CPT-11 and SN-38 in serum and urine samples. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20110101 |
| Secondary signet-ring cell adenocarcinoma of urinary bladder from a gastric primary. | Urology annals 20110101 |
| Effects of bolus injection of 5-fluorouracil on steady-state plasma concentrations of 5-fluorouracil in Japanese patients with advanced colorectal cancer. | International journal of medical sciences 20110101 |
| Common side effects and interactions of colorectal cancer therapeutic agents. | The Journal of practical nursing 20110101 |
| How to Treat a Signal? Current Basis for RET-Genotype-Oriented Choice of Kinase Inhibitors for the Treatment of Medullary Thyroid Cancer. | Journal of thyroid research 20110101 |
| First-line therapy for metastatic colorectal carcinoma: modified FOLFOX4 or FOLFIRI-bevacizumab. | Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20110101 |
| Tracheoesophageal fistula closed by chemoradiotherapy in lung cancer. | Case reports in oncology 20110101 |
| Glioblastoma-derived leptin induces tube formation and growth of endothelial cells: comparison with VEGF effects. | BMC cancer 20110101 |
| Neoadjuvant treatment of colorectal liver metastases is associated with altered contrast enhancement on computed tomography. | Cancer imaging : the official publication of the International Cancer Imaging Society 20110101 |
| The Role of EGFR Inhibitors in the Treatment of Metastatic Anal Canal Carcinoma: A Case Series. | Journal of oncology 20110101 |
| Anaplastic thyroid cancer: a review of epidemiology, pathogenesis, and treatment. | Journal of oncology 20110101 |
| Teratoma with malignant transformation: a case report with pathological, cytogenetic, and immunohistochemistry analysis. | Sarcoma 20110101 |
| The Gap between Tobacco Treatment Guidelines, Health Service Organization, and Clinical Practice in Comprehensive Cancer Centres. | Journal of oncology 20110101 |
| Association of laboratory parameters with viral factors in patients with hepatitis C. | Virology journal 20110101 |
| 5-fluorouracil/leucovorin combined with irinotecan and oxaliplatin (FOLFIRINOX) as second-line chemotherapy in patients with metastatic pancreatic adenocarcinoma. | Oncology 20110101 |
| E7080, a multi-targeted tyrosine kinase inhibitor suppresses tumor cell migration and invasion. | BMC cancer 20110101 |
| Clinical therapeutics in pregnancy. | Journal of biomedicine & biotechnology 20110101 |
| Second-line chemotherapy with irinotecan, 5-fluorouracil and leucovorin (FOLFIRI) in relapsed or metastatic gastric cancer: lessons from clinical practice. | Tumori 20110101 |
| Synergistic activity of ixabepilone plus other anticancer agents: preclinical and clinical evidence. | Therapeutic advances in medical oncology 20110101 |
| Reassessing the need for primary tumor surgery in unresectable metastatic colorectal cancer: overview and perspective. | Therapeutic advances in medical oncology 20110101 |
| Irinotecan as a second-line monotherapy for small cell lung cancer. | Asian Pacific journal of cancer prevention : APJCP 20110101 |
| Safety and pharmacokinetics of motesanib in combination with gemcitabine and erlotinib for the treatment of solid tumors: a phase 1b study. | BMC cancer 20110101 |
| Adjuvant chemoradiotherapy for locoregionally advanced and high-risk salivary gland malignancies. | Head & neck oncology 20110101 |
| Latest developments and emerging treatment options in the management of stomach cancer. | Cancer management and research 20110101 |
| Electroporation increases antitumoral efficacy of the bcl-2 antisense G3139 and chemotherapy in a human melanoma xenograft. | Journal of translational medicine 20110101 |
| Phase I study of telatinib (BAY 57-9352): analysis of safety, pharmacokinetics, tumor efficacy, and biomarkers in patients with colorectal cancer. | Vascular cell 20110101 |
| [Hypertension as a predictive factor of effect of bevacizumab in treatment of colorectal cancer]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110101 |
| [Chemotherapy in patients with non-resectable colorectal cancer metastases to the liver: systemic or regional?]. | Voprosy onkologii 20110101 |
| Intramedullary spinal cord metastasis from colonic carcinoma presenting as Brown-Séquard syndrome: a case report. | Journal of medical case reports 20110101 |
| Survival of patients with colon and rectal cancer in central and northern Denmark, 1998-2009. | Clinical epidemiology 20110101 |
| SPARC, FOXP3, CD8 and CD45 correlation with disease recurrence and long-term disease-free survival in colorectal cancer. | PloS one 20110101 |
| Drug therapy for hereditary cancers. | Hereditary cancer in clinical practice 20110101 |
| Asiatic acid inhibits pro-angiogenic effects of VEGF and human gliomas in endothelial cell culture models. | PloS one 20110101 |
| Rhodococcus equi venous catheter infection: a case report and review of the literature. | Journal of medical case reports 20110101 |
| Current and emerging pharmacotherapies for the treatment of relapsed small cell lung cancer. | Clinical Medicine Insights. Oncology 20110101 |
| Early dissemination of bevacizumab for advanced colorectal cancer: a prospective cohort study. | BMC cancer 20110101 |
| Expression of Transketolase like gene 1 (TKTL1) predicts disease-free survival in patients with locally advanced rectal cancer receiving neoadjuvant chemoradiotherapy. | BMC cancer 20110101 |
| Regulation of apoptotic effects by erythrocarpine E, a cytotoxic limonoid from Chisocheton erythrocarpus in HSC-4 human oral cancer cells. | PloS one 20110101 |
| A randomized, phase III trial of capecitabine plus bevacizumab (Cape-Bev) versus capecitabine plus irinotecan plus bevacizumab (CAPIRI-Bev) in first-line treatment of metastatic colorectal cancer: the AIO KRK 0110 trial/ML22011 trial. | BMC cancer 20110101 |
| Management options in triple-negative breast cancer. | Breast cancer : basic and clinical research 20110101 |
| Clinical management of gastric cancer: results of a multicentre survey. | BMC cancer 20110101 |
| Bacteria, food, and cancer. | F1000 biology reports 20110101 |
| Neoadjuvant capecitabine, radiotherapy, and bevacizumab (CRAB) in locally advanced rectal cancer: results of an open-label phase II study. | Radiation oncology (London, England) 20110101 |
| Effect of 5-fluorouracil treatment on SN-38 absorption from intestine in rats. | Biological & pharmaceutical bulletin 20110101 |
| Anticancer activities of six selected natural compounds of some Cameroonian medicinal plants. | PloS one 20110101 |
| The chemotherapeutic drug 5-fluorouracil promotes PKR-mediated apoptosis in a p53-independent manner in colon and breast cancer cells. | PloS one 20110101 |
| Phase II study of weekly paclitaxel and capecitabine in patients with metastatic or recurrent esophageal squamous cell carcinoma. | BMC cancer 20110101 |
| Preferential expression of potential markers for cancer stem cells in large cell neuroendocrine carcinoma of the lung. An FFPE proteomic study. | Journal of clinical bioinformatics 20110101 |
| Fermented wheat germ extract--nutritional supplement or anticancer drug? | Nutrition journal 20110101 |
| Translational medicine and reliability of single-nucleotide polymorphism studies: can we believe in SNP reports or not? | International journal of medical sciences 20110101 |
| Assessment of anti-cytogenotoxic effects of quercetin in animals treated with topotecan. | Oxidative medicine and cellular longevity 20110101 |
| Increased betulinic acid induced cytotoxicity and radiosensitivity in glioma cells under hypoxic conditions. | Radiation oncology (London, England) 20110101 |
| Drug metabolizing enzyme activities versus genetic variances for drug of clinical pharmacogenomic relevance. | Clinical proteomics 20110101 |
| Phospho-ERK and AKT status, but not KRAS mutation status, are associated with outcomes in rectal cancer treated with chemoradiotherapy. | Radiation oncology (London, England) 20110101 |
| Evaluation of two models for human topoisomerase I interaction with dsDNA and camptothecin derivatives. | PloS one 20110101 |
| Clinical herbal interactions with conventional drugs: from molecules to maladies. | Current medicinal chemistry 20110101 |
| Remarkable inhibitory effects of hybrid liposomes on growth of human colon cancer cells through induction of cell cycle arrest along with apoptosis. | International journal of nanomedicine 20110101 |
| Use of capecitabine in management of early colon cancer. | Cancer management and research 20110101 |
| Pre-clinical efficacy and safety of experimental vaccines based on non-replicating vaccinia vectors against yellow fever. | PloS one 20110101 |
| Gene expression signature analysis identifies vorinostat as a candidate therapy for gastric cancer. | PloS one 20110101 |
| A systems approach for tumor pharmacokinetics. | PloS one 20110101 |
| Gastroduodenal, intestinal and colonic permeability during anticancer therapy. | Hepato-gastroenterology 20110101 |
| The efficacy of chemotherapy in patients with high-grade metastatic colon cancer. | Hepato-gastroenterology 20110101 |
| Absorption and tolerability of fentanyl buccal soluble film (FBSF) in patients with cancer in the presence of oral mucositis. | Journal of pain research 20110101 |
| Granulocyte colony-stimulating factors for febrile neutropenia prophylaxis following chemotherapy: systematic review and meta-analysis. | BMC cancer 20110101 |
| Clinical pharmacogenomic testing of KRAS, BRAF and EGFR mutations by high resolution melting analysis and ultra-deep pyrosequencing. | BMC cancer 20110101 |
| Systematic in-vitro evaluation of the NCI/NIH Developmental Therapeutics Program Approved Oncology Drug Set for the identification of a candidate drug repertoire for MLL-rearranged leukemia. | OncoTargets and therapy 20110101 |
| Is there any advantage to combined trastuzumab and chemotherapy in perioperative setting her 2neu positive localized gastric adenocarcinoma? | World journal of surgical oncology 20110101 |
| Non-small cell lung carcinoma in an adolescent manifested by acute paraplegia due to spinal metastases: a case report. | Journal of medical case reports 20110101 |
| Exploring DNA topoisomerase I ligand space in search of novel anticancer agents. | PloS one 20110101 |
| Phase II study of irinotecan plus S-1 combination for previously untreated advanced non-small cell lung cancer: Hokkaido Lung Cancer Clinical Study Group Trial (HOT) 0601. | Oncology 20110101 |
| Adenovirus-mediated siRNA targeting Bcl-xL inhibits proliferation, reduces invasion and enhances radiosensitivity of human colorectal cancer cells. | World journal of surgical oncology 20110101 |
| Targeting ανβ3 and ανβ5 inhibits photon-induced hypermigration of malignant glioma cells. | Radiation oncology (London, England) 20110101 |
| Biological evaluation of 5-fluorouracil nanoparticles for cancer chemotherapy and its dependence on the carrier, PLGA. | International journal of nanomedicine 20110101 |
| Identification of a conserved anti-apoptotic protein that modulates the mitochondrial apoptosis pathway. | PloS one 20110101 |
| Transketolase-like 1 expression is modulated during colorectal cancer progression and metastasis formation. | PloS one 20110101 |
| Liposomal doxorubicin improves radiotherapy response in hypoxic prostate cancer xenografts. | Radiation oncology (London, England) 20110101 |
| Successful treatment of a patient with HER2-positive metastatic gastric cancer with third-line combination therapy with irinotecan, 5-fluorouracil, leucovorin and trastuzumab (FOLFIRI-T). | Onkologie 20110101 |
| Unusual metachronous isolated inguinal lymph node metastasis from adenocarcinoma of the sigmoid colon. | World journal of surgical oncology 20110101 |
| TFE3 Translocation-Associated Renal Cell Carcinoma Presenting as Avascular Necrosis of the Femur in a 19-Year-Old Patient: Case Report and Review of the Literature. | Case reports in medicine 20110101 |
| Looking to the future: biomarkers in the management of pancreatic adenocarcinoma. | International journal of molecular sciences 20110101 |
| High-density real-time PCR-based in vivo toxicogenomic screen to predict organ-specific toxicity. | International journal of molecular sciences 20110101 |
| The continuation of bevacizumab following disease progression in patients with metastatic colorectal cancer offers a survival benefit. | Hepato-gastroenterology 20110101 |
| Long survival of primary diffuse leptomeningeal gliomatosis following radiotherapy and temozolomide: case report and literature review. | European journal of medical research 20110101 |
| A case of marked response to preoperative chemoradiotherapy for rectal cancer with para-aortic lymph node metastasis. | International surgery 20110101 |
| Mucosal atrophy in collagenous colitis: a case report. | BMC gastroenterology 20110101 |
| The human epidermal growth factor receptor (EGFR) gene in European patients with advanced colorectal cancer harbors infrequent mutations in its tyrosine kinase domain. | BMC medical genetics 20110101 |
| Clinical significance in the number of involved lymph nodes in patients that underwent surgery for pathological stage III-N2 non-small cell lung cancer. | Journal of cardiothoracic surgery 20110101 |
| Compound Kushen Injection suppresses human breast cancer stem-like cells by down-regulating the canonical Wnt/β-catenin pathway. | Journal of experimental & clinical cancer research : CR 20110101 |
| SCOPE1: a randomised phase II/III multicentre clinical trial of definitive chemoradiation, with or without cetuximab, in carcinoma of the oesophagus. | BMC cancer 20110101 |
| BRAF mutations in advanced cancers: clinical characteristics and outcomes. | PloS one 20110101 |
| [Genetic polymorphisms of SLCO1B1 for drug pharmacokinetics and its clinical implications]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110101 |
| Parallel screening of FDA-approved antineoplastic drugs for identifying sensitizers of TRAIL-induced apoptosis in cancer cells. | BMC cancer 20110101 |
| Genetic variation of the IL-28B promoter affecting gene expression. | PloS one 20110101 |
| Strong nuclear EGFR expression in colorectal carcinomas is associated with cyclin-D1 but not with gene EGFR amplification. | Diagnostic pathology 20110101 |
| Second-line chemotherapy for carboplatin/paclitaxel-refractory ovarian cancer: are multi-agent chemotherapies of little value truly? | European journal of gynaecological oncology 20110101 |
| Rare case of intracranial Salmonella enteritidis abscess following glioblastoma resection: Case report and review of the literature. | Surgical neurology international 20110101 |
| A peptide of SPARC interferes with the interaction between caspase8 and Bcl2 to resensitize chemoresistant tumors and enhance their regression in vivo. | PloS one 20110101 |
| Immunogenicity of panitumumab in combination chemotherapy clinical trials. | BMC clinical pharmacology 20110101 |
| Biomarkers in tumor angiogenesis and anti-angiogenic therapy. | International journal of molecular sciences 20110101 |
| Selenium and lung cancer: a systematic review and meta analysis. | PloS one 20110101 |
| Laparoscopic low anterior resection for hematogenous rectal metastasis from gastric adenocarcinoma: a case report. | World journal of surgical oncology 20110101 |
| A rare bladder cancer--small cell carcinoma: review and update. | Orphanet journal of rare diseases 20110101 |
| Small interfering RNA targeting mcl-1 enhances proteasome inhibitor-induced apoptosis in various solid malignant tumors. | BMC cancer 20110101 |
| Nanoparticle mediated targeting of VEGFR and cancer stem cells for cancer therapy. | Vascular cell 20110101 |
| Inhibitors of Glioma Growth that Reveal the Tumour to the Immune System. | Clinical Medicine Insights. Oncology 20110101 |
| Long-term survival and improved quality of life after chemoradiotherapy to treat esophageal small cell carcinoma: a report of two cases. | Hepato-gastroenterology 20110101 |
| Small bowel adenocarcinoma presenting with refractory iron deficiency anemia - case report and review of literature. | Case reports in oncology 20110101 |
| EGFR-targeted hybrid plasmonic magnetic nanoparticles synergistically induce autophagy and apoptosis in non-small cell lung cancer cells. | PloS one 20110101 |
| Ten-year survival after liver resection for colorectal metastases: systematic review and meta-analysis. | ISRN oncology 20110101 |
| Innovative Therapies against Human Glioblastoma Multiforme. | ISRN oncology 20110101 |
| Prognostic significance of a systemic inflammatory response in patients receiving first-line palliative chemotherapy for recurred or metastatic gastric cancer. | BMC cancer 20110101 |
| T cells and adoptive immunotherapy: recent developments and future prospects in gastrointestinal oncology. | Clinical & developmental immunology 20110101 |
| Biodistribution and pharmacokinetics of 188Re-liposomes and their comparative therapeutic efficacy with 5-fluorouracil in C26 colonic peritoneal carcinomatosis mice. | International journal of nanomedicine 20110101 |
| Isolated splenic metastasis from rectal carcinoma: a rare occurrence. | Case reports in oncology 20110101 |
| An aggressive signet ring cell carcinoma of the prostate in a Japanese man. | Case reports in oncology 20110101 |
| Role of survival post-progression in phase III trials of systemic chemotherapy in advanced non-small-cell lung cancer: a systematic review. | PloS one 20110101 |
| Treatment of colorectal liver metastases. | World journal of surgical oncology 20110101 |
| Diffusion MR Imaging of the Brain in Patients with Cancer. | International journal of molecular imaging 20110101 |
| Peroxisome Proliferator-Activated Receptor-γ Ligands Alter Breast Cancer Cell Motility through Modulation of the Plasminogen Activator System. | Journal of oncology 20110101 |
| Interaction of human multidrug and toxin extrusion 1 (MATE1) transporter with antineoplastic agents. | Drug metabolism and drug interactions 20110101 |
| Stopping rules employing response rates, time to progression, and early progressive disease for phase II oncology trials. | BMC medical research methodology 20110101 |
| Biomarker analysis of cetuximab plus oxaliplatin/leucovorin/5-fluorouracil in first-line metastatic gastric and oesophago-gastric junction cancer: results from a phase II trial of the Arbeitsgemeinschaft Internistische Onkologie (AIO). | BMC cancer 20110101 |
| Characterization of Abcc4 gene amplification in stepwise-selected mouse J774 macrophages resistant to the topoisomerase II inhibitor ciprofloxacin. | PloS one 20110101 |
| Comparative Structures and Evolution of Vertebrate Carboxyl Ester Lipase (CEL) Genes and Proteins with a Major Role in Reverse Cholesterol Transport. | Cholesterol 20110101 |
| Tegafur/gimeracil/oteracil (S-1) approved for the treatment of advanced gastric cancer in adults when given in combination with cisplatin: a review comparing it with other fluoropyrimidine-based therapies. | OncoTargets and therapy 20110101 |
| Assessment of a novel VEGF targeted agent using patient-derived tumor tissue xenograft models of colon carcinoma with lymphatic and hepatic metastases. | PloS one 20110101 |
| Oxaliplatin but not irinotecan impairs posthepatectomy liver regeneration in a murine model. | International journal of hepatology 20110101 |
| The utility of Aspirin in Dukes C and High Risk Dukes B Colorectal cancer--the ASCOLT study: study protocol for a randomized controlled trial. | Trials 20110101 |
| Cancer chemopreventive ability of conjugated linolenic acids. | International journal of molecular sciences 20110101 |
| IT-141, a Polymer Micelle Encapsulating SN-38, Induces Tumor Regression in Multiple Colorectal Cancer Models. | Journal of drug delivery 20110101 |
| Radiotherapy and 'new' drugs-new side effects? | Radiation oncology (London, England) 20110101 |
| The immune response to tumors as a tool toward immunotherapy. | Clinical & developmental immunology 20110101 |
| Changes in human fecal microbiota due to chemotherapy analyzed by TaqMan-PCR, 454 sequencing and PCR-DGGE fingerprinting. | PloS one 20110101 |
| A phase II study of irinotecan in combination with cisplatin as second-line chemotherapy in patients with metastatic or locally advanced gastric cancer. | Chang Gung medical journal 20110101 |
| Oxaliplatin-induced neuropathy in colorectal cancer. | Journal of oncology 20110101 |
| S100A10 protein expression is associated with oxaliplatin sensitivity in human colorectal cancer cells. | Proteome science 20110101 |
| Multi-tyrosine kinase inhibitors in preclinical studies for pediatric CNS AT/RT: Evidence for synergy with Topoisomerase-I inhibition. | Cancer cell international 20110101 |
| Outcomes of resection for colorectal cancer hepatic metastases stratified by evolving eras of treatment. | World journal of surgical oncology 20110101 |
| KRAS mutations testing in colorectal carcinoma patients in Italy: from guidelines to external quality assessment. | PloS one 20110101 |
| Napsin a and thyroid transcription factor-1-positive cerebellar tumor with epidermal growth factor receptor mutation. | Case reports in oncology 20110101 |
| Small cell carcinoma of the tonsil treated with irinotecan and Cisplatin: a case report and literature review. | Case reports in oncology 20110101 |
| Monoclonal antibodies in gynecological cancer: a critical point of view. | Clinical & developmental immunology 20110101 |
| Oxaliplatin-incorporated micelles eliminate both cancer stem-like and bulk cell populations in colorectal cancer. | International journal of nanomedicine 20110101 |
| Novel immunotherapeutic strategies of gastric cancer treatment. | Journal of biomedicine & biotechnology 20110101 |
| SN-38:β-cyclodextrin inclusion complex for in situ solidifying injectable polymer implants. | Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20110101 |
| [The role of chemotherapy and targeted antiVEGF- and antiEGFR-therapy in metastatic colorectal cancer: a case report of long-term and intensive response]. | Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 20110101 |
| The state of research into children with cancer across Europe: new policies for a new decade. | Ecancermedicalscience 20110101 |
| A phase II study of oxaliplatin with 5-FU/folinic acid and concomitant radiotherapy as a preoperative treatment in patients with locally advanced rectal cancer. | Biomedical imaging and intervention journal 20110101 |
| The prospective role of plant products in radiotherapy of cancer: a current overview. | Frontiers in pharmacology 20110101 |
| A regimen of taxol, Ifosfamide, and platinum for recurrent advanced squamous cell cancer of the anal canal. | Chemotherapy research and practice 20110101 |
| Neoadjuvant treatment in rectal cancer: actual status. | Chemotherapy research and practice 20110101 |
| New agents targeting angiogenesis in glioblastoma. | Chemotherapy research and practice 20110101 |
| Colorectal liver metastases. | International journal of surgical oncology 20110101 |
| Yttrium-90 radioembolization for colorectal cancer liver metastases: a single institution experience. | International journal of surgical oncology 20110101 |
| Clinical outcome of laparoscopic intersphincteric resection combined with transanal rectal dissection for t3 low rectal cancer in patients with a narrow pelvis. | International journal of surgical oncology 20110101 |
| Optimizing Liposomal Cisplatin Efficacy through Membrane Composition Manipulations. | Chemotherapy research and practice 20110101 |
| Bevacizumab improves quality of life in patients with recurrent glioblastoma. | Chemotherapy research and practice 20110101 |
| Neurotoxicity caused by the treatment with platinum analogues. | Chemotherapy research and practice 20110101 |
| Multidrug resistance in breast cancer: from in vitro models to clinical studies. | International journal of breast cancer 20110101 |
| Suffocating cancer: hypoxia-associated epimutations as targets for cancer therapy. | Clinical epigenetics 20110101 |
| HADHA is a potential predictor of response to platinum-based chemotherapy for lung cancer. | Asian Pacific journal of cancer prevention : APJCP 20110101 |
| Radiation Dose Escalation in Stage III Non-Small-Cell Lung Cancer. | Frontiers in oncology 20110101 |
| The Grand Challenges in GI Tract Cancers. | Frontiers in oncology 20110101 |
| Phase I study of celecoxib with concurrent irinotecan, Cisplatin, and radiation therapy for patients with unresectable locally advanced non-small cell lung cancer. | Frontiers in oncology 20110101 |
| The insulin receptor: a new target for cancer therapy. | Frontiers in endocrinology 20110101 |
| Therapeutic targeting of cancer stem cells. | Frontiers in oncology 20110101 |
| Protease addiction and synthetic lethality in cancer. | Frontiers in oncology 20110101 |
| Combined modality approaches in the management of adult glioblastoma. | Frontiers in oncology 20110101 |
| Adjuvant chemotherapy for early stage non-small cell lung cancer. | Frontiers in oncology 20110101 |
| Investigational approaches for mesothelioma. | Frontiers in oncology 20110101 |
| Patient counseling about herbal-drug interactions. | African journal of traditional, complementary, and alternative medicines : AJTCAM 20110101 |
| Familial adenomatous polyposis with synchronous invasive colonic carcinomas and metastatic jejunal adenocarcinoma in a Nigerian male. | Rare tumors 20101231 |
| Common arm comparative outcomes analysis of phase 3 trials of cisplatin + irinotecan versus cisplatin + etoposide in extensive stage small cell lung cancer: final patient-level results from Japan Clinical Oncology Group 9511 and Southwest Oncology Group 0124. | Cancer 20101215 |
| Irinotecan-involved regimens for advanced gastric cancer: a pooled-analysis of clinical trials. | World journal of gastroenterology 20101214 |
| Guesstimates are not good enough for determining what is happening in routine care. | British journal of cancer 20101207 |
| An online gene expression assay for determining adjuvant therapy eligibility in patients with stage 2 or 3 colon cancer. | British journal of cancer 20101207 |
| Molecular determinants of anti-EGFR sensitivity and resistance in metastatic colorectal cancer. | British journal of cancer 20101207 |
| ERCC1 Expression Analysis to Guide Therapy in Non-Small Cell Lung Cancer. | PLoS currents 20101206 |
| MDR1 polymorphism role in patients treated with cetuximab and irinotecan in irinotecan refractory colorectal cancer. | Medical oncology (Northwood, London, England) 20101201 |
| Multimodality management for 145 cases of Merkel cell carcinoma. | Medical oncology (Northwood, London, England) 20101201 |
| Protective effects of propolis and related polyphenolic/flavonoid compounds against toxicity induced by irinotecan. | Medical oncology (Northwood, London, England) 20101201 |
| A phase II study of irinotecan, continuous 5-fluorouracil, and leucovorin (FOLFIRI) combination chemotherapy for patients with recurrent or metastatic gastric cancer previously treated with a fluoropyrimidine-based regimen. | American journal of clinical oncology 20101201 |
| Synergistic antitumor activity of the SN-38-incorporating polymeric micelles NK012 with S-1 in a mouse model of non-small cell lung cancer. | International journal of cancer 20101201 |
| Inter-observer agreement between dermatologists and oncologists in assessing dermatological toxicities in patients with metastatic colorectal cancer treated by cetuximab-based chemotherapies: a pilot comparative study. | European journal of cancer (Oxford, England : 1990) 20101201 |
| P-glycoprotein, but not multidrug resistance protein 4, plays a role in the systemic clearance of irinotecan and SN-38 in mice. | Drug metabolism letters 20101201 |
| Polymeric micelles in anticancer therapy: targeting, imaging and triggered release. | Pharmaceutical research 20101201 |
| Population pharmacokinetics of CPT-11 (irinotecan) in gastric cancer patients with peritoneal seeding after its intraperitoneal administration. | European journal of clinical pharmacology 20101201 |
| CYP3A4*16 and CYP3A4*18 alleles found in East Asians exhibit differential catalytic activities for seven CYP3A4 substrate drugs. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
| Mesenchymal mode of migration participates in pulmonary metastasis of mouse osteosarcoma LM8. | Clinical & experimental metastasis 20101201 |
| Cerebrospinal fluid leak during treatment with bevacizumab and irinotecan after carmustine-impregnated wafers placement in patients with grade 2 oligodendroglioma and glioblastoma multiforme: report of two cases and review of literature. | Cancer investigation 20101201 |
| Simultaneous quantification of ten cytotoxic drugs by a validated LC-ESI-MS/MS method. | Analytical and bioanalytical chemistry 20101201 |
| [Influence of pre-surgical chemotherapy on liver parenchyma and post-surgical outcome of patients subjected to hepatectomy due to colorectal carcinoma metastases]. | Cirugia espanola 20101201 |
| Camptothecins compared with etoposide in combination with platinum analog in extensive stage small cell lung cancer: systematic review with meta-analysis. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20101201 |
| Discovery and selectivity-profiling of 4-benzylamino 1-aza-9-oxafluorene derivatives as lead structures for IGF-1R inhibitors. | Bioorganic & medicinal chemistry letters 20101201 |
| E phage gene transfection enhances sensitivity of lung and colon cancer cells to chemotherapeutic agents. | International journal of oncology 20101201 |
| Effects of the HDAC inhibitor CG2 in combination with irinotecan, 5-fluorouracil, or oxaliplatin on HCT116 colon cancer cells and xenografts. | Oncology reports 20101201 |
| An explorative study on the clinical utility of baseline and serial serum tumour marker measurements in advanced upper gastrointestinal cancer. | Oncology reports 20101201 |
| Phase I/II study of a 3-week cycle of irinotecan and S-1 in patients with advanced colorectal cancer. | Cancer science 20101201 |
| Mitomycin-C, 5-fluorouracil, and leucovorin as a salvage therapy in patients with metastatic colorectal adenocarcinoma. | Asia-Pacific journal of clinical oncology 20101201 |
| Use of nanoscale delivery systems to maintain synergistic drug ratios in vivo. | Expert opinion on drug delivery 20101201 |
| A phase 2 multicenter study of irinotecan and cisplatinum as neoadjuvant treatment in patients with locally advanced cervical cancer. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20101201 |
| Genome-wide mRNA and microRNA profiling of the NCI 60 cell-line screen and comparison of FdUMP[10] with fluorouracil, floxuridine, and topoisomerase 1 poisons. | Molecular cancer therapeutics 20101201 |
| [Hepatic lesions induced by systemic chemotherapy for digestive cancer]. | Annales de pathologie 20101201 |
| Bevacizumab and glioblastomas, a single-centre experience: how disease history and characteristics may affect clinical outcome. | Anticancer research 20101201 |
| Cetuximab Plus irinotecan in pretreated metastatic colorectal cancer progressing on irinotecan: the LABEL study. | Clinical colorectal cancer 20101201 |
| Hepatic arterial infusion of 5-fluorouracil for patients with liver metastases from colorectal cancer refractory to standard systemic chemotherapy: a multicenter, retrospective analysis. | Clinical colorectal cancer 20101201 |
| Oxaliplatin-induced chronic peripheral neurotoxicity: a prospective analysis in patients with colorectal cancer. | Cancer research and treatment : official journal of Korean Cancer Association 20101201 |
| Proteomic analysis of cell lines to identify the irinotecan resistance proteins. | Journal of biosciences 20101201 |
| In vitro adenosine triphosphate based chemotherapy response assay in gastric cancer. | Journal of gastric cancer 20101201 |
| Cetuximab-induced hypomagnesaemia aggravates peripheral sensory neurotoxicity caused by oxaliplatin. | Journal of gastrointestinal oncology 20101201 |
| BRAF p.Val600Glu (V600E) Testing for Assessment of Treatment Options in Metastatic Colorectal Cancer. | PLoS currents 20101126 |
| Cancer pharmacogenomics and pharmacoepidemiology: setting a research agenda to accelerate translation. | Journal of the National Cancer Institute 20101117 |
| Dendritic cell vaccine in addition to FOLFIRI regimen improve antitumor effects through the inhibition of immunosuppressive cells in murine colorectal cancer model. | Vaccine 20101116 |
| The insulin-like growth factor I receptor/insulin receptor tyrosine kinase inhibitor PQIP exhibits enhanced antitumor effects in combination with chemotherapy against colorectal cancer models. | Clinical cancer research : an official journal of the American Association for Cancer Research 20101115 |
| Laser induced fluorescence and photochemical derivatization for trace determination of camptothecin. | Talanta 20101115 |
| Selection of evodiamine as a novel topoisomerase I inhibitor by structure-based virtual screening and hit optimization of evodiamine derivatives as antitumor agents. | Journal of medicinal chemistry 20101111 |
| Dose-finding study and pharmacogenomic analysis of fixed-rate infusion of gemcitabine, irinotecan and bevacizumab in pretreated metastatic colorectal cancer patients. | British journal of cancer 20101109 |
| A retrospective observational study on the safety and efficacy of first-line treatment with bevacizumab combined with FOLFIRI in metastatic colorectal cancer. | British journal of cancer 20101109 |
| Cetuximab plus chronomodulated irinotecan, 5-fluorouracil, leucovorin and oxaliplatin as neoadjuvant chemotherapy in colorectal liver metastases: POCHER trial. | British journal of cancer 20101109 |
| KRAS mutation detection and prognostic potential in sporadic colorectal cancer using high-resolution melting analysis. | British journal of cancer 20101109 |
| Anthracycline rechallenge using pegylated liposomal doxorubicin in patients with metastatic breast cancer: a pooled analysis using individual data from four prospective trials. | British journal of cancer 20101109 |
| Bevacizumab in combination with biweekly capecitabine and irinotecan, as first-line treatment for patients with metastatic colorectal cancer. | British journal of cancer 20101109 |
| Cancer. Targeting bacteria to improve cancer therapy. | Science (New York, N.Y.) 20101105 |
| Alleviating cancer drug toxicity by inhibiting a bacterial enzyme. | Science (New York, N.Y.) 20101105 |
| The impact of new treatment options for advanced colorectal cancer on routine care: results of a retrospective analysis of 206 consecutive patients treated in a community-based oncology group practice in Germany. | European journal of cancer care 20101101 |
| Sequential surgical resection of hepatic and pulmonary metastases from colorectal cancer. | Langenbeck's archives of surgery 20101101 |
| Chemoradiotherapy for locoregionally advanced squamous cell carcinoma of the base of tongue. | Head & neck 20101101 |
| Molecular predictive and prognostic markers in colon cancer. | Cancer treatment reviews 20101101 |
| Liposomal cisplatin combined with paclitaxel versus cisplatin and paclitaxel in non-small-cell lung cancer: a randomized phase III multicenter trial. | Annals of oncology : official journal of the European Society for Medical Oncology 20101101 |
| Medium-term results of neoadjuvant systemic chemotherapy using irinotecan, 5-fluorouracil, and leucovorin in patients with locally advanced rectal cancer. | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20101101 |
| Neoadjuvant chemotherapy followed by radical hysterectomy plus postoperative chemotherapy but no radiotherapy for Stage IB2-IIB cervical cancer--irinotecan and platinum chemotherapy. | Gynecologic oncology 20101101 |
| Targeting poly(ADP-ribose) polymerase activity for cancer therapy. | Cellular and molecular life sciences : CMLS 20101101 |
| Hyaluronan inhibits postchemotherapy tumor regrowth in a colon carcinoma xenograft model. | Molecular cancer therapeutics 20101101 |
| Biweekly docetaxel, cisplatin, and 5-fluorouracil (DCF) chemotherapy for advanced esophageal squamous cell carcinoma: a phase I dose-escalation study. | Cancer chemotherapy and pharmacology 20101101 |
| Randomized phase III study of panitumumab with fluorouracil, leucovorin, and irinotecan (FOLFIRI) compared with FOLFIRI alone as second-line treatment in patients with metastatic colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101101 |
| Expression of phosphorylated Akt in patients with small cell carcinoma of the lung indicates good prognosis. | Pathology international 20101101 |
| Combination 5-fluorouracil, folinic acid and cisplatin (LV5FU2-CDDP) followed by gemcitabine or the reverse sequence in metastatic pancreatic cancer: final results of a randomised strategic phase III trial (FFCD 0301). | Gut 20101101 |
| A phase I clinical trial of FOLFIRI in combination with the pan-cyclin-dependent kinase (CDK) inhibitor flavopiridol. | Cancer chemotherapy and pharmacology 20101101 |
| Vorinostat synergises with capecitabine through upregulation of thymidine phosphorylase. | British journal of cancer 20101101 |
| [Effects of irinotecan and 5-FU combination therapy in gastric cancer--is combination therapy synergic?]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| [Risk associated with severe hematological toxicity in patients with advanced or recurrent colonic cancer receiving combination chemotherapy of S-1 and irinotecan hydrochloride]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| [A case of complete resection of a squamous cell lung cancer invading diaphragm after neoadjuvant chemotherapy of nedaplatin and irinotecan]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| [Two cases of colorectal cancer presenting with periodic, transient elevation of serum iron after chemotherapy including irinotecan]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| [Weekly irinotecan plus capecitabine as a second-line chemotherapy for advanced gastric cancer: an analysis of 21 cases]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20101101 |
| XELIRI or FOLFIRI as salvage therapy in advanced pancreatic cancer. | Anticancer research 20101101 |
| Colorectal cancer screening for average-risk North Americans: an economic evaluation. | PLoS medicine 20101101 |
| Therapeutic implications of resistance to molecular therapies in metastatic colorectal cancer. | Cancer treatment reviews 20101101 |
| Maintenance therapy in colon cancer. | Cancer treatment reviews 20101101 |
| Update on capecitabine alone and in combination regimens in colorectal cancer patients. | Cancer treatment reviews 20101101 |
| Consensus recommendations for the use of anti-egfr therapies in metastatic colorectal cancer. | Current oncology (Toronto, Ont.) 20101101 |
| Irinotecan or oxaliplatin combined with 5-fluorouracil and leucovorin as first-line therapy for advanced colorectal cancer: a meta-analysis. | Chinese medical journal 20101101 |
| [Our experience of the treatment with cetuximab for unresectable advanced colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| [A case of small cell carcinoma of esophagus treated by chemotherapy with CDDP plus CPT-11 and radiotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| [A case of pneumocystis pneumonia during chemotherapy for gastric cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| [A clinical case of lymph node recurrence after resection of gastric cancer successfully treated by combination chemotherapy with irinotecan and cisplatin]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| [A successful case with CPT-11 + CDDP chemotherapy for recurrent gastric cancer of the remnant stomach]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| [A long-term survival case of bilateral ovarian metastasis of progressive gastric cancer treated by chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| [Two cases of gastric endocrine cell carcinoma]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| [A case of gastric endocrine cell carcinoma with liver metastases treated with S-1/CDDP]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| [The efficacy of cetuximab for metastatic colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| [A case of multiple lung and liver metastases from colon cancer treated with clinical benefit by hepatic arterial infusion chemotherapy plus cetuximab mono-therapy after standard chemotherapy failure]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| [Adrenalectomy for solitary adrenal metastasis from colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| [A long-term survival case of rectal cancer with Virchow's lymph node metastasis by multimodality therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| [A case of recurrent sigmoid colon cancer with adrenal and para-aortic lymph node metastasis successfully treated by operation and chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| [Hepatic resection after systemic chemotherapy for liver metastasis of colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| [A case of unresectable multiple hepatic metastases from colorectal cancer successfully treated with IRIS (S-1, CPT-11) therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| [A long-term disease-free survival case of advanced rectal cancer with massive metastasis to the lateral pelvic and para-aortic lymph nodes]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| [An experience of curative resection of local recurrent rectal cancer with high-level sacrectomy after preoperative chemo-radiation therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| [A case of synchronous double cancer of stomach and lung responding to neoadjuvant chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101101 |
| Topoisomerase I inhibitors in the treatment of primary CNS malignancies: an update on recent trends. | Anti-cancer agents in medicinal chemistry 20101101 |
| Antiangiogenic agents in advanced gastrointestinal malignancies: past, present and a novel future. | Oncotarget 20101101 |
| Systemic Therapy for Metastatic Colorectal Cancer: Patterns of Chemotherapy and Biologic Therapy Use in US Medical Oncology Practice. | Journal of oncology practice 20101101 |
| A Phase Ib dose-escalation study to evaluate safety and tolerability of the addition of the aminopeptidase inhibitor tosedostat (CHR-2797) to paclitaxel in patients with advanced solid tumours. | British journal of cancer 20101026 |
| Estimating prognosis and palliation based on tumour marker CA 19-9 and quality of life indicators in patients with advanced pancreatic cancer receiving chemotherapy. | British journal of cancer 20101026 |
| A pilot study on the immunogenicity of dendritic cell vaccination during adjuvant oxaliplatin/capecitabine chemotherapy in colon cancer patients. | British journal of cancer 20101026 |
| Activity of irinotecan and temozolomide in the presence of O6-methylguanine-DNA methyltransferase inhibition in neuroblastoma pre-clinical models. | British journal of cancer 20101026 |
| Phase II study of nedaplatin and irinotecan with concurrent thoracic radiotherapy in patients with locally advanced non-small-cell lung cancer. | British journal of cancer 20101026 |
| Carboxyl-terminated PAMAM-SN38 conjugates: synthesis, characterization, and in vitro evaluation. | Bioconjugate chemistry 20101020 |
| Randomized phase II window trial of two schedules of irinotecan with vincristine in patients with first relapse or progression of rhabdomyosarcoma: a report from the Children's Oncology Group. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101020 |
| [Management of metastatic colorectal cancer]. | La Revue du praticien 20101020 |
| Insulin-like growth factor 1 expression correlates with clinical outcome in K-RAS wild type colorectal cancer patients treated with cetuximab and irinotecan. | International journal of cancer 20101015 |
| Phase I study of NK012, a novel SN-38-incorporating micellar nanoparticle, in adult patients with solid tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20101015 |
| Cetuximab in small bowel adenocarcinoma: a new friend? | British journal of cancer 20101012 |
| Genotoxic effects of irinotecan combined with the novel platinum(II) complexes in human cancer cells. | Chemico-biological interactions 20101006 |
| A phase I trial of lomeguatrib and irinotecan in metastatic colorectal cancer. | Cancer chemotherapy and pharmacology 20101001 |
| Efficacy of CR3294, a new benzamidine derivative, in the prevention of 5-fluorouracil-induced gastrointestinal mucositis and diarrhea in mice. | Cancer chemotherapy and pharmacology 20101001 |
| Se-methylselenocysteine sensitizes hypoxic tumor cells to irinotecan by targeting hypoxia-inducible factor 1alpha. | Cancer chemotherapy and pharmacology 20101001 |
| The maximum tolerated dose and biologic effects of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) in combination with irinotecan for patients with refractory solid tumors. | Cancer chemotherapy and pharmacology 20101001 |
| Belotecan for relapsing small-cell lung cancer patients initially treated with an irinotecan-containing chemotherapy: a phase II trial. | Lung cancer (Amsterdam, Netherlands) 20101001 |
| Irinotecan plus bolus/infusional 5-Fluorouracil and leucovorin in patients with pretreated advanced pancreatic carcinoma: a multicenter experience of the Gruppo Oncologico Italia Meridionale. | American journal of clinical oncology 20101001 |
| Genetic modulation of the Let-7 microRNA binding to KRAS 3'-untranslated region and survival of metastatic colorectal cancer patients treated with salvage cetuximab-irinotecan. | The pharmacogenomics journal 20101001 |
| Clinical features of interstitial lung disease induced by standard chemotherapy (FOLFOX or FOLFIRI) for colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20101001 |
| Quality of life of patients receiving platinum-based chemotherapy plus cetuximab first line for recurrent and/or metastatic squamous cell carcinoma of the head and neck. | Annals of oncology : official journal of the European Society for Medical Oncology 20101001 |
| Itraconazole for invasive fungal infection with pediatric malignancies. | Pediatrics international : official journal of the Japan Pediatric Society 20101001 |
| Neoadjuvant chemotherapy in patients with stage IV colorectal cancer: a comparison of histological response in liver metastases, primary tumors, and regional lymph nodes. | Annals of surgical oncology 20101001 |
| Recovery of liver function after the cessation of preoperative chemotherapy for colorectal liver metastasis. | Annals of surgical oncology 20101001 |
| Phase I/II study of capecitabine plus oxaliplatin (XELOX) plus bevacizumab as first-line therapy in Japanese patients with metastatic colorectal cancer. | Japanese journal of clinical oncology 20101001 |
| Therapeutic significance of a D-dimer cut-off level of >3 µg/ml in colorectal cancer patients treated with standard chemotherapy plus bevacizumab. | Japanese journal of clinical oncology 20101001 |
| A phase I study of gemcitabine plus irinotecan for advanced NSCLC: Japan Clinical Oncology Group Trial (JCOG9904). | Japanese journal of clinical oncology 20101001 |
| The antitumor activity of NK012, an SN-38-incorporating micelle, in combination with bevacizumab against lung cancer xenografts. | Cancer 20101001 |
| Adjuvant oxaliplatin- or irinotecan-containing chemotherapy improves overall survival following resection of metachronous colorectal liver metastases. | International journal of colorectal disease 20101001 |
| Therapy of small cell lung cancer with emphasis on oral topotecan. | Lung cancer (Amsterdam, Netherlands) 20101001 |
| A phase II study of combination therapy with irinotecan and S-1 (IRIS) in patients with advanced colorectal cancer. | Cancer chemotherapy and pharmacology 20101001 |
| Successful treatment of advanced pancreatoblastoma by a pylorus-preserving pancreatoduodenectomy after radiation and high-dose chemotherapy. | Pediatric surgery international 20101001 |
| Toxicity of irinotecan-eluting beads in the treatment of hepatic malignancies: results of a multi-institutional registry. | Cardiovascular and interventional radiology 20101001 |
| Matrix metalloproteinases are possible mediators for the development of alimentary tract mucositis in the dark agouti rat. | Experimental biology and medicine (Maywood, N.J.) 20101001 |
| Fast liquid chromatography-tandem mass spectrometry method for routine assessment of irinotecan metabolic phenotype. | Therapeutic drug monitoring 20101001 |
| Effects of herbal products on the metabolism and transport of anticancer agents. | Expert opinion on drug metabolism & toxicology 20101001 |
| Tumor regression and curability of preclinical neuroblastoma models by PEGylated SN38 (EZN-2208), a novel topoisomerase I inhibitor. | Clinical cancer research : an official journal of the American Association for Cancer Research 20101001 |
| Beta-casein nanoparticles as an oral delivery system for chemotherapeutic drugs: impact of drug structure and properties on co-assembly. | Pharmaceutical research 20101001 |
| First-line treatment of malignant glioma with carmustine implants followed by concomitant radiochemotherapy: a multicenter experience. | Neurosurgical review 20101001 |
| [Evaluation of ADC mapping as an early predictor for tumor response to chemotherapy in recurrent glioma treated with bevacizumab/irinotecan: proof of principle]. | RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 20101001 |
| Detailed distribution of NK012, an SN-38-incorporating micelle, in the liver and its potent antitumor effects in mice bearing liver metastases. | Clinical cancer research : an official journal of the American Association for Cancer Research 20101001 |
| Irinotecan overcomes the resistance to 5-fluorouracil in human colon cancer xenografts by down-regulation of intratumoral thymidylate synthase. | Oncology reports 20101001 |
| [mRNA quantification. The next challenge in routine diagnostics]. | Der Pathologe 20101001 |
| Genetic instability influences drug response in cancer cells. | Current drug targets 20101001 |
| Ewing's sarcoma. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20101001 |
| Capecitabine in combination with oxaliplatin or irinotecan in elderly patients with advanced colorectal cancer: results of a randomised phase II study. | Annals of oncology : official journal of the European Society for Medical Oncology 20101001 |
| Differences in efficacy and safety between capecitabine and infusional 5-fluorouracil when combined with irinotecan for the treatment of metastatic colorectal cancer. | Clinical colorectal cancer 20101001 |
| Effects of mannose-binding lectin polymorphisms on irinotecan-induced febrile neutropenia. | The oncologist 20101001 |
| [Current status and perspectives of biologics in the treatment of metastatic colorectal cancer]. | Nihon rinsho. Japanese journal of clinical medicine 20101001 |
| Hyperbilirubinemia syndromes (Gilbert-Meulengracht, Crigler-Najjar, Dubin-Johnson, and Rotor syndrome). | Best practice & research. Clinical gastroenterology 20101001 |
| Induction chemoradiation therapy with cisplatin plus irinotecan followed by surgical resection for superior sulcus tumor. | Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia 20101001 |
| Synergistic effects of topoisomerase I inhibitor, SN38, on Fas-mediated apoptosis. | Anticancer research 20101001 |
| Molecular predictors of combination targeted therapies (cetuximab, bevacizumab) in irinotecan-refractory colorectal cancer (BOND-2 study). | Anticancer research 20101001 |
| Irinotecan/fluorouracil/leucovorin or the same regimen followed by oxaliplatin/fluorouracil/leucovorin in metastatic colorectal cancer. | Anticancer research 20101001 |
| A retrospective analysis of non-platinum-based first- and second-line chemotherapy in patients with advanced non-small cell lung cancer. | Anticancer research 20101001 |
| Detection of failure of bevacizumab treatment for malignant glioma based on urinary matrix metalloproteinase activity. | Brain tumor pathology 20101001 |
| [A rare case of large cell neuroendocrine carcinoma of the thymus]. | Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20101001 |
| [Efficacy of cetuximab combined with chemotherapy for patients with advanced colorectal cancer and unclear K-ras status]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20101001 |
| [Evaluation of bevacizumab combined with irinotecan-based regimen as the first-line treatment for patients with metastatic colorectal cancer]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20101001 |
| Chemotherapy of metastatic colorectal cancer. | Prescrire international 20101001 |
| Molecular identification and targeting of colorectal cancer stem cells. | Oncotarget 20101001 |
| Synergistic induction of cell death in liver tumor cells by TRAIL and chemotherapeutic drugs via the BH3-only proteins Bim and Bid. | Cell death & disease 20101001 |
| A phase I, dose-finding study of sunitinib in combination with irinotecan in patients with advanced solid tumours. | British journal of cancer 20100928 |
| Prognostic significance of AMP-activated protein kinase expression and modifying effect of MAPK3/1 in colorectal cancer. | British journal of cancer 20100928 |
| Germline genetic variation, cancer outcome, and pharmacogenetics. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100910 |
| Identification of chemicals and their metabolites from PHY906, a Chinese medicine formulation, in the plasma of a patient treated with irinotecan and PHY906 using liquid chromatography/tandem mass spectrometry (LC/MS/MS). | Journal of chromatography. A 20100910 |
| Thymidine synthase, thymidine phosphorylase, and excision repair cross-complementation group 1 expression as predictive markers of capecitabine plus cisplatin chemotherapy as first-line treatment for patients with advanced oesophageal squamous cell carcinoma. | British journal of cancer 20100907 |
| Liquid chromatography-tandem mass spectrometric assay for the quantitation in human plasma of the novel indenoisoquinoline topoisomerase I inhibitors, NSC 743400 and NSC 725776. | Journal of pharmaceutical and biomedical analysis 20100905 |
| KRAS mutational analysis for colorectal cancer. Application: pharmacogenomic. | PLoS currents 20100902 |
| Efficacy and safety of bevacizumab plus capecitabine and irinotecan regimen for metastatic colorectal cancer. | Medical oncology (Northwood, London, England) 20100901 |
| Role of low dose capecitabine combined to irinotecan in advanced and metastatic gastric cancer. | Medical oncology (Northwood, London, England) 20100901 |
| Therapeutic targeting of melanoma cells using neural stem cells expressing carboxylesterase, a CPT-11 activating enzyme. | Current stem cell research & therapy 20100901 |
| Evidence of heterogeneity within colorectal liver metastases for allelic losses, mRNA level expression and in vitro response to chemotherapeutic agents. | International journal of cancer 20100901 |
| Analysis of anti-proliferative and chemosensitizing effects of sunitinib on human esophagogastric cancer cells: Synergistic interaction with vandetanib via inhibition of multi-receptor tyrosine kinase pathways. | International journal of cancer 20100901 |
| Metronomic treatment of malignant glioma xenografts with irinotecan (CPT-11) inhibits angiogenesis and tumor growth. | Journal of neuro-oncology 20100901 |
| Antitumor activity and pharmacokinetics of oral gimatecan on pediatric cancer xenografts. | Cancer chemotherapy and pharmacology 20100901 |
| Vorinostat enhances the cytotoxic effects of the topoisomerase I inhibitor SN38 in glioblastoma cell lines. | Journal of neuro-oncology 20100901 |
| Overall survival with cisplatin-gemcitabine and bevacizumab or placebo as first-line therapy for nonsquamous non-small-cell lung cancer: results from a randomised phase III trial (AVAiL). | Annals of oncology : official journal of the European Society for Medical Oncology 20100901 |
| Rebound tumour progression after the cessation of bevacizumab therapy in patients with recurrent high-grade glioma. | Journal of neuro-oncology 20100901 |
| Chemotherapy of advanced small-bowel adenocarcinoma: a multicenter AGEO study. | Annals of oncology : official journal of the European Society for Medical Oncology 20100901 |
| A multicenter international randomized phase III study comparing cisplatin in combination with irinotecan or etoposide in previously untreated small-cell lung cancer patients with extensive disease. | Annals of oncology : official journal of the European Society for Medical Oncology 20100901 |
| Bevacizumab in recurrent high-grade pediatric gliomas. | Neuro-oncology 20100901 |
| Phase I/II study of oncolytic herpes simplex virus NV1020 in patients with extensively pretreated refractory colorectal cancer metastatic to the liver. | Human gene therapy 20100901 |
| Canine spontaneous glioma: a translational model system for convection-enhanced delivery. | Neuro-oncology 20100901 |
| Camptothecin attenuates cytochrome P450 3A4 induction by blocking the activation of human pregnane X receptor. | The Journal of pharmacology and experimental therapeutics 20100901 |
| Phase 2 trial of preoperative irinotecan plus cisplatin and conformal radiotherapy, followed by surgery for esophageal cancer. | Cancer 20100901 |
| Immunoglobulin G fragment C receptor polymorphisms and KRAS mutations: are they useful biomarkers of clinical outcome in advanced colorectal cancer treated with anti-EGFR-based therapy? | Cancer science 20100901 |
| Comparison of DC Bead-irinotecan and DC Bead-topotecan drug eluting beads for use in locoregional drug delivery to treat pancreatic cancer. | Journal of materials science. Materials in medicine 20100901 |
| Emerging clinical principles on the use of bevacizumab for the treatment of malignant gliomas. | Cancer 20100901 |
| Systematic review of benefits and risks of second-line irinotecan monotherapy for advanced colorectal cancer. | Anti-cancer drugs 20100901 |
| Phase I trial of weekly irinotecan and paclitaxel combined with carboplatin in patients with advanced cancer: a Hellenic Cooperative Oncology Group Study. | Anti-cancer drugs 20100901 |
| A randomized phase II study of a combination of docetaxel and S-1 versus docetaxel monotherapy in patients with non-small cell lung cancer previously treated with platinum-based chemotherapy: results of Okayama Lung Cancer Study Group (OLCSG) Trial 0503. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20100901 |
| SG2285, a novel C2-aryl-substituted pyrrolobenzodiazepine dimer prodrug that cross-links DNA and exerts highly potent antitumor activity. | Cancer research 20100901 |
| Tumor thickness at the tumor-normal interface: a novel pathologic indicator of chemotherapy response in hepatic colorectal metastases. | The American journal of surgical pathology 20100901 |
| Bevacizumab with FOLFOXIRI (irinotecan, oxaliplatin, fluorouracil, and folinate) as first-line treatment for metastatic colorectal cancer: a phase 2 trial. | The Lancet. Oncology 20100901 |
| Irinotecan plus S-1 (IRIS) versus fluorouracil and folinic acid plus irinotecan (FOLFIRI) as second-line chemotherapy for metastatic colorectal cancer: a randomised phase 2/3 non-inferiority study (FIRIS study). | The Lancet. Oncology 20100901 |
| Impaired irinotecan biotransformation in hepatic microsomal fractions from patients with chronic liver disease. | British journal of clinical pharmacology 20100901 |
| [Metastatic gastric cancer: does second-line chemotherapy make sense?]. | Deutsche medizinische Wochenschrift (1946) 20100901 |
| Gastric Cancer Working Group report. | Japanese journal of clinical oncology 20100901 |
| Lung cancer working group report. | Japanese journal of clinical oncology 20100901 |
| Antiepileptic drug interactions - principles and clinical implications. | Current neuropharmacology 20100901 |
| 7'-Methyl-5'-oxo-2',3'-dihydro-spiro-[1,3-dioxolane-2,1'(5'H)-indolizine]-6'-carbonitrile. | Acta crystallographica. Section E, Structure reports online 20100901 |
| Using bevacizumab with different chemotherapeutic regimens in metastatic colorectal cancer: balancing utility with low toxicity. | Therapeutic advances in medical oncology 20100901 |
| Are herbal medicines ripe for the cancer clinic? | Science translational medicine 20100818 |
| The four-herb Chinese medicine PHY906 reduces chemotherapy-induced gastrointestinal toxicity. | Science translational medicine 20100818 |
| Capecitabine for locally advanced and metastatic colorectal cancer: A review. | World journal of gastrointestinal oncology 20100815 |
| Functional characterization of human and cynomolgus monkey UDP-glucuronosyltransferase 1A1 enzymes. | Life sciences 20100814 |
| Poorly differentiated endocrine carcinoma of the pancreas responded to gemcitabine: Case report. | World journal of gastroenterology 20100814 |
| Phase III study comparing second- and third-generation regimens with concurrent thoracic radiotherapy in patients with unresectable stage III non-small-cell lung cancer: West Japan Thoracic Oncology Group WJTOG0105. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100810 |
| UGT1A and TYMS genetic variants predict toxicity and response of colorectal cancer patients treated with first-line irinotecan and fluorouracil combination therapy. | British journal of cancer 20100810 |
| Cisplatin/Irinotecan versus carboplatin/paclitaxel as definitive chemoradiotherapy for locoregionally advanced esophageal cancer. | American journal of clinical oncology 20100801 |
| A phase I study of flavopiridol in combination with gemcitabine and irinotecan in patients with metastatic cancer. | American journal of clinical oncology 20100801 |
| Synergistic interactions between aminoflavone, paclitaxel and camptothecin in human breast cancer cells. | Cancer chemotherapy and pharmacology 20100801 |
| Cellular and molecular mechanisms for the synergistic cytotoxicity elicited by oxaliplatin and pemetrexed in colon cancer cell lines. | Cancer chemotherapy and pharmacology 20100801 |
| Phase II NCCTG trial of RT + irinotecan and adjuvant BCNU plus irinotecan for newly diagnosed GBM. | Journal of neuro-oncology 20100801 |
| Management of isolated nonresectable liver metastases in colorectal cancer patients: a case-control study of isolated hepatic perfusion with melphalan versus systemic chemotherapy. | Annals of oncology : official journal of the European Society for Medical Oncology 20100801 |
| Multimodal treatment options for bilobar colorectal liver metastases. | Langenbeck's archives of surgery 20100801 |
| A case report of metastatic neuroendocrine carcinoma of the right adrenal gland successfully treated with chemotherapy and surgery. | International journal of clinical oncology 20100801 |
| PTCH1, a receptor of Hedgehog signaling pathway, is correlated with metastatic potential of colorectal cancer. | Upsala journal of medical sciences 20100801 |
| Phase II study of sequential cisplatin plus 5-fluorouracil/leucovorin (5-FU/LV) followed by irinotecan plus 5-FU/LV followed by docetaxel plus 5-FU/LV in patients with metastatic gastric or gastro-oesophageal junction adenocarcinoma. | Cancer chemotherapy and pharmacology 20100801 |
| Choroidal metastases from esophageal adenocarcinoma responding to chemotherapy with cisplatin and irinotecan. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100801 |
| Pharmacogenetics of irinotecan disposition and toxicity: a review. | Current clinical pharmacology 20100801 |
| Altered phospholipid transfer protein gene expression and serum lipid profile by topotecan. | Biochemical pharmacology 20100801 |
| Different DNA immobilization strategies for the interaction of anticancer drug irinotecan with DNA based on electrochemical DNA biosensors. | Combinatorial chemistry & high throughput screening 20100801 |
| BCRP/ABCG2 confers anticancer drug resistance without covalent dimerization. | Cancer science 20100801 |
| Risk factors for developing a new venous thromboembolism in ambulatory patients with non-hematologic malignancies and impact on survival for gastroesophageal malignancies. | Journal of thrombosis and haemostasis : JTH 20100801 |
| Dose-dependent association between UGT1A1*28 genotype and irinotecan-induced neutropenia: low doses also increase risk. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100801 |
| The role of targeted agents in preoperative chemoradiation for rectal cancer. | Cancer 20100801 |
| Addition of sunitinib to cetuximab and irinotecan in patients with heavily pre-treated advanced colorectal cancer. | Acta oncologica (Stockholm, Sweden) 20100801 |
| Biochemical and molecular analysis of carboxylesterase-mediated hydrolysis of cocaine and heroin. | British journal of pharmacology 20100801 |
| Association of carboxylesterase 1A genotypes with irinotecan pharmacokinetics in Japanese cancer patients. | British journal of clinical pharmacology 20100801 |
| Consequences of chemotherapy on resection of colorectal liver metastases. | Journal of visceral surgery 20100801 |
| Effect of poly (ethylene oxide)-poly (propylene oxide)-poly (ethylene oxide) micelles on pharmacokinetics and intestinal toxicity of irinotecan hydrochloride: potential involvement of breast cancer resistance protein (ABCG2). | The Journal of pharmacy and pharmacology 20100801 |
| Prospective evaluation of angiogenic, hypoxic and EGFR-related biomarkers in recurrent glioblastoma multiforme treated with cetuximab, bevacizumab and irinotecan. | APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20100801 |
| Taste alterations in cancer patients receiving chemotherapy: a neglected side effect? | The oncologist 20100801 |
| Efficacy of high-dose chemotherapy and autologous stem cell transplantation in patients with relapsed medulloblastoma: a report on the Korean Society for Pediatric Neuro-Oncology (KSPNO)-S-053 study. | Journal of Korean medical science 20100801 |
| When more is worse in clinical research and clinical practice. | American journal of clinical oncology 20100801 |
| Progress in metastatic colorectal cancer: growing role of cetuximab to optimize clinical outcome. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20100801 |
| [Performance of a portable continuous infusion pump (SUREFUSER A) in continuous infusion of 5-FU]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100801 |
| [A case of gastric adenosquamous carcinoma successfully treated with second-line chemotherapy (CPT-11 and CDDP)]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100801 |
| [A case of irinotecan-induced interstitial pneumonia during treatment of recurrent colon cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100801 |
| [Effect of anti-EGFR monoclonal antibody on chemosensitivity of human colon cancer cells and the mechanism]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20100801 |
| Randomized phase II study of sequential docetaxel and irinotecan with 5-fluorouracil/folinic acid (leucovorin) in patients with advanced gastric cancer: the GATAC trial. | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20100801 |
| Second-line chemotherapy with irinotecan plus cisplatin after the failure of S-1 monotherapy for advanced gastric cancer. | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20100801 |
| Survivin may be a Key Target for Oxaliplatin. | Journal of the Korean Society of Coloproctology 20100801 |
| Oncologic outcome after cessation or dose reduction of capecitabine in patients with colon cancer. | Journal of the Korean Society of Coloproctology 20100801 |
| 5-Fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency. | British journal of cancer 20100727 |
| Multi-centre phase II clinical trial of yttrium-90 resin microspheres alone in unresectable, chemotherapy refractory colorectal liver metastases. | British journal of cancer 20100727 |
| BMS-690514, a VEGFR and EGFR tyrosine kinase inhibitor, shows anti-tumoural activity on non-small-cell lung cancer xenografts and induces sequence-dependent synergistic effect with radiation. | British journal of cancer 20100727 |
| Understanding chemotherapy treatment pathways of advanced colorectal cancer patients to inform an economic evaluation in the United Kingdom. | British journal of cancer 20100727 |
| Phase II study of the anti-cytotoxic T-lymphocyte-associated antigen 4 monoclonal antibody, tremelimumab, in patients with refractory metastatic colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100720 |
| Whole cell-ELISA to measure the gammaH2AX response of six aneugens and eight DNA-damaging chemicals. | Mutation research 20100719 |
| Vascular endothelial growth factors and vascular permeability. | Cardiovascular research 20100715 |
| Oncological outcome of unresectable lung metastases without extrapulmonary metastases in colorectal cancer. | World journal of gastroenterology 20100714 |
| Clinicopathological features and outcome in advanced colorectal cancer patients with synchronous vs metachronous metastases. | British journal of cancer 20100713 |
| Cetuximab plus FOLFOX6 or FOLFIRI in metastatic colorectal cancer: CECOG trial. | World journal of gastroenterology 20100707 |
| Preclinical pharmacokinetic/pharmacodynamic models to predict synergistic effects of co-administered anti-cancer agents. | Cancer chemotherapy and pharmacology 20100701 |
| Cetuximab administered once every second week to patients with metastatic colorectal cancer: a two-part pharmacokinetic/pharmacodynamic phase I dose-escalation study. | Annals of oncology : official journal of the European Society for Medical Oncology 20100701 |
| Irinotecan and colorectal cancer: the role of p53, VEGF-C and alpha-B-crystallin expression. | International journal of colorectal disease 20100701 |
| Progression-free survival in first-line chemotherapy is a prognostic factor in second-line chemotherapy in patients with advanced gastric cancer. | Journal of cancer research and clinical oncology 20100701 |
| Raltitrexed and oxaliplatin hepatic arterial infusion for advanced colorectal cancer: a retrospective study. | Anti-cancer drugs 20100701 |
| Phase II study of combination chemotherapy with biweekly cetuximab and irinotecan for pre-treated metastatic colorectal cancer harboring wild-type KRAS. | Japanese journal of clinical oncology 20100701 |
| Dose-dependent association between UGT1A1*28 polymorphism and irinotecan-induced diarrhoea: a meta-analysis. | European journal of cancer (Oxford, England : 1990) 20100701 |
| Triplet combination of carboplatin, irinotecan, and etoposide in the first-line treatment of extensive small-cell lung cancer: a single-institution phase II study. | Anti-cancer drugs 20100701 |
| Cytotoxicity and topo I targeting activity of substituted 10--nitrogenous heterocyclic aromatic group derivatives of SN-38. | European journal of medicinal chemistry 20100701 |
| Extended phase I evaluation of vincristine, irinotecan, temozolomide, and antibiotic in children with refractory solid tumors. | Pediatric blood & cancer 20100701 |
| Shared regulation of UGT1A7 by hepatocyte nuclear factor (HNF) 1alpha and HNF4alpha. | Drug metabolism and disposition: the biological fate of chemicals 20100701 |
| Evolving pharmacotherapeutic strategies for small bowel adenocarcinoma. | Expert opinion on pharmacotherapy 20100701 |
| Phase II study of sequential triplet chemotherapy, irinotecan and cisplatin followed by amrubicin, in patients with extensive-stage small cell lung cancer: West Japan Thoracic Oncology Group Study 0301. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20100701 |
| Phase 1/2 clinical study of irinotecan and oral S-1 (IRIS) in patients with advanced gastric cancer. | Advances in therapy 20100701 |
| Intestinal complications after palliative treatment for asymptomatic patients with unresectable stage IV colorectal cancer. | Journal of surgical oncology 20100701 |
| The UGT1A1*28 polymorphism correlates with erlotinib's effect on SN-38 glucuronidation. | European journal of cancer (Oxford, England : 1990) 20100701 |
| Clinical and economic evaluation of first-line therapy with FOLFIRI or modified FOLFOX6 for metastatic colorectal cancer. | Japanese journal of clinical oncology 20100701 |
| Irinotecan pharmacogenomics. | Pharmacogenomics 20100701 |
| Comparative study of chemoembolization loadable beads: in vitro drug release and physical properties of DC bead and hepasphere loaded with doxorubicin and irinotecan. | Journal of vascular and interventional radiology : JVIR 20100701 |
| Phase II trial of imatinib maintenance therapy after irinotecan and cisplatin in patients with c-Kit-positive, extensive-stage small-cell lung cancer. | Clinical lung cancer 20100701 |
| [Recent developments of pharmacogenomics in the treatment of colorectal cancers]. | Annales pharmaceutiques francaises 20100701 |
| Development of bronchiolitis obliterans organizing pneumonia with platinum-based chemotherapy for metastatic rectal cancer. | Clinical colorectal cancer 20100701 |
| Racial/ethnic and age disparities in chemotherapy selection for colorectal cancer. | The American journal of managed care 20100701 |
| [Modified FOLFIRI (l-LV, 5-fluorouracil and irinotecan) therapy for Japanese patients with metastatic colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100701 |
| [A resected case of effective treatment with S-1+CPT-11 combination chemotherapy for advanced gastric cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100701 |
| Adverse events associated with anti-EGFR therapies for the treatment of metastatic colorectal cancer. | Current oncology (Toronto, Ont.) 20100701 |
| Efficacy of the monoclonal antibody EGFR inhibitors for the treatment of metastatic colorectal cancer. | Current oncology (Toronto, Ont.) 20100701 |
| KRAS mutation testing in the treatment of metastatic colorectal cancer with anti-EGFR therapies. | Current oncology (Toronto, Ont.) 20100701 |
| Hepatic arterial infusion with oxaliplatin, irinotecan and doxifluridine for unresectable liver metastases of colorectal cancer. | Anticancer research 20100701 |
| [Large cell neuroendocrine carcinoma of the mediastinum]. | Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20100701 |
| Recurrent high-grade glioma. | Current treatment options in neurology 20100701 |
| Neutropenic enterocolitis: A continuing medical and surgical challenge. | North American journal of medical sciences 20100701 |
| Endometrial stromal sarcoma with selective polyvinyl alcohol embolization of a pulmonary metastasis after recurrent hemoptysis and expansive growth. | Rare tumors 20100630 |
| A phase II trial of dose-dense chemotherapy, followed by surgical resection and/or thoracic radiotherapy, in locally advanced thymoma: report of a Japan Clinical Oncology Group trial (JCOG 9606). | British journal of cancer 20100629 |
| Lack of efficacy of bevacizumab plus irinotecan in children with recurrent malignant glioma and diffuse brainstem glioma: a Pediatric Brain Tumor Consortium study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100620 |
| Mismatch repair system decreases cell survival by stabilizing the tetraploid G1 arrest in response to SN-38. | International journal of cancer 20100615 |
| BRAF mutations, microsatellite instability status and cyclin D1 expression predict metastatic colorectal patients' outcome. | British journal of cancer 20100608 |
| Decreased exposure to sunitinib due to concomitant administration of ifosfamide: results of a phase I and pharmacokinetic study on the combination of sunitinib and ifosfamide in patients with advanced solid malignancies. | British journal of cancer 20100608 |
| Regarding: 'Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array'. | British journal of cancer 20100608 |
| Pilot study of irinotecan/oxalipltin (IROX) combination chemotherapy for patients with gemcitabine- and 5-fluorouracil- refractory pancreatic cancer. | Investigational new drugs 20100601 |
| Comparison of chemotherapy for unresectable pulmonary high-grade non-small cell neuroendocrine carcinoma and small-cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20100601 |
| Improving disease control in advanced colorectal cancer: Panitumumab and cetuximab. | Critical reviews in oncology/hematology 20100601 |
| A phase II study of irinotecan with biweekly, low dose leucovorin and bolus and continuous infusion 5-fluorouracil (modified FOLFIRI) as first line therapy for patients with recurrent or metastatic gastric cancer. | American journal of clinical oncology 20100601 |
| Etoposide plus cisplatin followed by concurrent chemo-radiotherapy and irinotecan plus cisplatin for patients with limited-stage small cell lung cancer: A multicenter phase II study. | Lung cancer (Amsterdam, Netherlands) 20100601 |
| A phase I study of capecitabine, irinotecan, celecoxib, and radiation as neoadjuvant therapy of patients with locally advanced rectal cancer. | American journal of clinical oncology 20100601 |
| Preparation and in vitro evaluation of actively targetable nanoparticles for SN-38 delivery against HT-29 cell lines. | Nanomedicine : nanotechnology, biology, and medicine 20100601 |
| The value of XPD and XRCC1 genotype polymorphisms to predict clinical outcome in metastatic colorectal carcinoma patients with irinotecan-based regimens. | Journal of cancer research and clinical oncology 20100601 |
| RECIST revised: implications for the radiologist. A review article on the modified RECIST guideline. | European radiology 20100601 |
| Oxidative stress therapy for solid tumors - a proposal. | Medical hypotheses 20100601 |
| Phase I study of daily irinotecan as a radiation sensitizer for locally advanced pancreatic cancer. | International journal of radiation oncology, biology, physics 20100601 |
| Phase II study of preoperative chemoradiotherapy (CRT) with irinotecan plus S-1 in locally advanced rectal cancer. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20100601 |
| Comparison of combination chemotherapy with irinotecan and cisplatin regimen administered every 2 or 4 weeks in pretreated patients with unresectable or recurrent gastric cancer: retrospective analysis. | International journal of clinical oncology 20100601 |
| Health-related quality of life in patients with advanced colorectal cancer: results from a phase II study of S-1 combined with irinotecan (CPT-11). | International journal of clinical oncology 20100601 |
| Dosing considerations for capecitabine-irinotecan regimens in the treatment of metastatic and/or locally advanced colorectal cancer. | American journal of clinical oncology 20100601 |
| Cytotoxic drugs up-regulate epidermal growth factor receptor (EGFR) expression in colon cancer cells and enhance their susceptibility to EGFR-targeted antibody-dependent cell-mediated-cytotoxicity (ADCC). | European journal of cancer (Oxford, England : 1990) 20100601 |
| Chemotherapy-induced liver injury in metastatic colorectal cancer: semiquantitative histologic analysis of 334 resected liver specimens shows that vascular injury but not steatohepatitis is associated with preoperative chemotherapy. | The American journal of surgical pathology 20100601 |
| Triplet schedule of weekly 5-fluorouracil and alternating irinotecan or oxaliplatin in advanced colorectal cancer: a dose-finding and phase II study. | Oncology reports 20100601 |
| Is there a role for mitomycin C in metastatic colorectal cancer? | Expert opinion on investigational drugs 20100601 |
| Pharmacokinetics of intraperitoneal irinotecan in a pig model. | Journal of surgical oncology 20100601 |
| Conatumumab, a fully human mAb against death receptor 5 for the treatment of cancer. | Current opinion in investigational drugs (London, England : 2000) 20100601 |
| A meta-analysis of randomized controlled trials comparing irinotecan/platinum with etoposide/platinum in patients with previously untreated extensive-stage small cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20100601 |
| Recently identified and potential targets for colon cancer treatment. | Future oncology (London, England) 20100601 |
| [Transition of chemotherapy for metastatic colorectal cancer and recent advances]. | Nihon rinsho. Japanese journal of clinical medicine 20100601 |
| Downregulation of cystine transporter xc by irinotecan in human head and neck cancer FaDu xenografts. | Chemotherapy 20100601 |
| [Third-line CPT-11 chemotherapy for gastric cancer cases of non-curative gastrectomy or recurrence]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100601 |
| [Utility of CPT-11 as salvage chemotherapy for progressive or recurrent breast cancer patients with multiple drug resistance]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100601 |
| [Current medicinal treatment of metastasized colorectal carcinoma]. | Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 20100601 |
| Targeted therapies in renal cell cancer: recent developments in imaging. | Targeted oncology 20100601 |
| Inhibition of Wnt signaling pathway decreases chemotherapy-resistant side-population colon cancer cells. | Anticancer research 20100601 |
| Pharmacokinetics of irinotecan in combination with biweekly cetuximab in patients with advanced colorectal cancer. | Anticancer research 20100601 |
| Overcoming multidrug resistance in human cancer cells by natural compounds. | Toxins 20100601 |
| Pharmacogenetic assessment of toxicity and outcome in patients with metastatic colorectal cancer treated with LV5FU2, FOLFOX, and FOLFIRI: FFCD 2000-05. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100520 |
| Weekly alternating therapy with irinotecan plus cisplatin and etoposide plus cisplatin in the treatment of patients with extensive small cell lung carcinoma. | Cancer 20100515 |
| Macrocyclic pyridyl polyoxazoles: selective RNA and DNA G-quadruplex ligands as antitumor agents. | Journal of medicinal chemistry 20100513 |
| Capecitabine and bevacizumab as first-line treatment in elderly patients with metastatic colorectal cancer. | British journal of cancer 20100511 |
| Thermodynamic studies and loading of 7-ethyl-10-hydroxycamptothecin into mesoporous silica particles MCM-41 in strongly acidic solutions. | The journal of physical chemistry. B 20100506 |
| Initial assessment, surveillance, and management of blood pressure in patients receiving vascular endothelial growth factor signaling pathway inhibitors. | Journal of the National Cancer Institute 20100505 |
| Additive effects of drug transporter genetic polymorphisms on irinotecan pharmacokinetics/pharmacodynamics in Japanese cancer patients. | Cancer chemotherapy and pharmacology 20100501 |
| The role of salvage reirradiation for malignant gliomas that progress on bevacizumab. | Journal of neuro-oncology 20100501 |
| The impact of carcinoembryonic antigen flare in patients with advanced colorectal cancer receiving first-line chemotherapy. | Annals of oncology : official journal of the European Society for Medical Oncology 20100501 |
| Effect of bevacizumab in older patients with metastatic colorectal cancer: pooled analysis of four randomized studies. | Journal of cancer research and clinical oncology 20100501 |
| Treatment of atypical central neurocytoma in a child with high dose chemotherapy and autologous stem cell rescue. | Journal of neuro-oncology 20100501 |
| Irinotecan as maintenance therapy in high-risk hepatoblastoma. | Pediatric blood & cancer 20100501 |
| Oral irinotecan for treatment of pediatric solid tumors: ready for prime time? | Pediatric blood & cancer 20100501 |
| Carcinoembryonic antigen surge in metastatic colorectal cancer patients responding to irinotecan combination chemotherapy. | Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20100501 |
| A humanized UGT1 mouse model expressing the UGT1A1*28 allele for assessing drug clearance by UGT1A1-dependent glucuronidation. | Drug metabolism and disposition: the biological fate of chemicals 20100501 |
| Secreted protein acidic and rich in cysteine-induced cellular senescence in colorectal cancers in response to irinotecan is mediated by P53. | Carcinogenesis 20100501 |
| [Hepatotoxicity of metastatic colorectal cancer chemotherapy: systematic review]. | Bulletin du cancer 20100501 |
| Operating characteristics of two independent sample design in phase I trials in paediatric oncology. | European journal of cancer (Oxford, England : 1990) 20100501 |
| Phase I study of irinotecan and cisplatin in combination with pelvic radiotherapy in the treatment of locally advanced cervical cancer: A GINECO trial. | Gynecologic oncology 20100501 |
| Phase II randomized study of two regimens of sequentially administered mitomycin C and irinotecan in patients with unresectable esophageal and gastroesophageal adenocarcinoma. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20100501 |
| Phosphate ester derivatives of homocamptothecin: synthesis, solution stabilities and antitumor activities. | Bioorganic & medicinal chemistry 20100501 |
| Cetuximab, bevacizumab, and irinotecan for patients with primary glioblastoma and progression after radiation therapy and temozolomide: a phase II trial. | Neuro-oncology 20100501 |
| Pharmacokinetic and pharmacodynamic investigation of irinotecan hydrochloride in pediatric patients with recurrent or progressive solid tumors. | International journal of clinical pharmacology and therapeutics 20100501 |
| [Cetuximab for patients with metastatic colorectal cancer-from the result of recent clinical trials]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100501 |
| [A case of stage IV gastric cancer with multiple liver metastases surviving for more than 4 years by treatment with chemotherapies without surgery]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100501 |
| [A case of gastric large cell neuroendocrine carcinoma (LCNEC) for whom chemotherapy of CDDP+CPT-11 proved very effective]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100501 |
| Cetuximab for the first-line treatment of metastatic colorectal cancer. | Health technology assessment (Winchester, England) 20100501 |
| [Hematological toxicity of some combined chemotherapy schemes involving aranoza]. | Eksperimental'naia i klinicheskaia farmakologiia 20100501 |
| Safety and efficacy of weekly 5-fluorouracil/folinic acid/oxaliplatin/irinotecan in the first-line treatment of gastrointestinal cancer. | Therapeutic advances in medical oncology 20100501 |
| Irinotecan in the adjuvant treatment of colon cancer: is the story finished or does personalized therapy open new opportunities? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100420 |
| Moxifloxacin increases anti-tumor and anti-angiogenic activity of irinotecan in human xenograft tumors. | Biochemical pharmacology 20100415 |
| Aprataxin tumor levels predict response of colorectal cancer patients to irinotecan-based treatment. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100415 |
| Tumor site-specific silencing of NF-kappaB p65 by targeted hollow gold nanosphere-mediated photothermal transfection. | Cancer research 20100415 |
| Expansion of CD133(+) colon cancer cultures retaining stem cell properties to enable cancer stem cell target discovery. | British journal of cancer 20100413 |
| Oncogenic KRAS sensitises colorectal tumour cells to chemotherapy by p53-dependent induction of Noxa. | British journal of cancer 20100413 |
| Epidemiology and pathophysiology of cancer-associated thrombosis. | British journal of cancer 20100413 |
| Phase II trials in patients with carcinoma of unknown primary: a pooled data analysis. | Investigational new drugs 20100401 |
| Management of metastatic breast cancer: monotherapy options for patients resistant to anthracyclines and taxanes. | American journal of clinical oncology 20100401 |
| Co-administration of irinotecan decreases the plasma concentration of an active metabolite of amrubicin, amrubicinol in rats. | Cancer chemotherapy and pharmacology 20100401 |
| Capecitabine in combination with oxaliplatin or irinotecan in elderly patients with advanced colorectal cancer: results of a randomized phase II study. | Annals of oncology : official journal of the European Society for Medical Oncology 20100401 |
| Phase II study of S-1 plus leucovorin in patients with metastatic colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20100401 |
| Association of SUMO1 and UBC9 genotypes with tumor response in non-small-cell lung cancer treated with irinotecan-based chemotherapy. | The pharmacogenomics journal 20100401 |
| Phase II of oral gimatecan in patients with recurrent epithelial ovarian, fallopian tube or peritoneal cancer, previously treated with platinum and taxanes. | Annals of oncology : official journal of the European Society for Medical Oncology 20100401 |
| KRAS mutation in colon cancer: a marker of resistance to EGFR-I therapy. | Annals of surgical oncology 20100401 |
| Fabrication of cationic nanomicelle from chitosan-graft-polycaprolactone as the carrier of 7-ethyl-10-hydroxy-camptothecin. | Colloids and surfaces. B, Biointerfaces 20100401 |
| Phase I trial of two schedules of vincristine, oral irinotecan, and temozolomide (VOIT) for children with relapsed or refractory solid tumors: a Children's Oncology Group phase I consortium study. | Pediatric blood & cancer 20100401 |
| Tumor marker evolution: comparison with imaging for assessment of response to chemotherapy in patients with colorectal liver metastases. | Annals of surgical oncology 20100401 |
| Genome-wide identification of chemosensitive single nucleotide polymorphism markers in colorectal cancers. | Cancer science 20100401 |
| Adjuvant therapy for colon cancer: learning from the past to inform the future. | Annals of surgical oncology 20100401 |
| An anticancer drug delivery system based on surfactant-templated mesoporous silica nanoparticles. | Biomaterials 20100401 |
| Trimodality therapy without a platinum compound for localized carcinoma of the esophagus and gastroesophageal junction. | Cancer 20100401 |
| Reduced incidence of infusion-related reactions in metastatic colorectal cancer during treatment with cetuximab plus irinotecan with combined corticosteroid and antihistamine premedication. | Cancer 20100401 |
| Doxorubicin and irinotecan drug-eluting beads for treatment of glioma: a pilot study in a rat model. | Journal of materials science. Materials in medicine 20100401 |
| Indispensability of UGT1A1*6 genotyping in Japanese cancer patients treated with irinotecan. | International journal of clinical oncology 20100401 |
| Cetuximab and chemoradiation for rectal cancer--is the water getting muddy? | Acta oncologica (Stockholm, Sweden) 20100401 |
| TRAIL gene-armed oncolytic poxvirus and oxaliplatin can work synergistically against colorectal cancer. | Gene therapy 20100401 |
| Interactions between cytotoxic chemotherapy and antiretroviral treatment in human immunodeficiency virus-infected patients with lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20100401 |
| Phase II trial of gemcitabine, irinotecan, and celecoxib in patients with advanced pancreatic cancer. | Journal of clinical gastroenterology 20100401 |
| Phase I evaluation of telatinib, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in combination with irinotecan and capecitabine in patients with advanced solid tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100401 |
| Recent advances in chemotherapy for advanced gastric cancer in Japan. | Surgery today 20100401 |
| Prognostic and predictive biomarkers in resected colon cancer: current status and future perspectives for integrating genomics into biomarker discovery. | The oncologist 20100401 |
| Chemotherapy: How useful is adjuvant irinotecan in stage IV CRC? | Nature reviews. Clinical oncology 20100401 |
| Efficacy and toxicity of chemoradiotherapy with carboplatin and irinotecan followed by consolidation docetaxel for unresectable stage III non-small cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20100401 |
| Palliative chemotherapy for pancreatic malignancies. | The Surgical clinics of North America 20100401 |
| Potent preclinical impact of metronomic low-dose oral topotecan combined with the antiangiogenic drug pazopanib for the treatment of ovarian cancer. | Molecular cancer therapeutics 20100401 |
| A randomized, placebo-controlled phase ii study evaluating the reduction of neutropenia and febrile neutropenia in patients with colorectal cancer receiving pegfilgrastim with every-2-week chemotherapy. | Clinical colorectal cancer 20100401 |
| [Prognostic factors and survival of metastatic colorectal cancer in the Sousse University Hospital (Tunisia): comparative study of two treatment period of 200 patients]. | Bulletin du cancer 20100401 |
| Role of capecitabine and irinotecan combination therapy in advanced or metastatic gastric cancer. | Expert review of anticancer therapy 20100401 |
| Recent advances in combined modality therapy. | The oncologist 20100401 |
| [Results of neoadjuvant chemotherapy using tri-weekly CDDP/CPT-11 for locally advanced cervical cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100401 |
| [Survey on the compliance of patients with continuous infusion of 5-fluorouracil via portable infusion pumps]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100401 |
| [A case of fluoropyrimidine-resistant recurrent colon cancer successfully treated with weekly administration of irinotecan]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100401 |
| Current issues in the targeted therapy of advanced colorectal cancer. | Discovery medicine 20100401 |
| [Short-term therapeutic effect and safety of endostar combined with XELIRI regimen in the treatment of advanced colorectal cancer]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20100401 |
| Chemotherapy for locally advanced and metastatic gastric cancer: state of the art and future perspectives. | European review for medical and pharmacological sciences 20100401 |
| Pharmacogenetic application in personalized cancer treatment. | Acta medica Indonesiana 20100401 |
| Glutathione modulators reverse the pro-tumour effect of growth factors enhancing WiDr cell response to chemotherapeutic agents. | Anticancer research 20100401 |
| Combination of RET siRNA and irinotecan inhibited the growth of medullary thyroid carcinoma TT cells and xenografts via apoptosis. | Cancer science 20100401 |
| Influence of the prodrugs 5-fluorocytosine and CPT-11 on ovarian cancer cells using genetically engineered stem cells: tumor-tropic potential and inhibition of ovarian cancer cell growth. | Cancer science 20100401 |
| Hepatocyte growth factor (HGF), heat shock proteins (HSPs) and multidrug resistance protein (MRP) expression in co-culture of colon tumor spheroids with normal cells after incubation with interleukin-1beta (IL-1beta) and/or camptothecin (CPT-11). | Indian journal of experimental biology 20100401 |
| Membrane transport proteins in human melanoma: associations with tumour aggressiveness and metastasis. | British journal of cancer 20100330 |
| Mitogen-activated protein kinase phosphatase-1 (MKP-1) impairs the response to anti-epidermal growth factor receptor (EGFR) antibody cetuximab in metastatic colorectal cancer patients. | British journal of cancer 20100330 |
| Chemotherapy for advanced gastric cancer. | The Cochrane database of systematic reviews 20100317 |
| Efficacy and tolerability of bevacizumab plus capecitabine as first-line therapy in patients with advanced hepatocellular carcinoma. | British journal of cancer 20100316 |
| KRAS status analysis and anti-EGFR therapies: is comprehensiveness a biologist's fancy or a clinical necessity? | British journal of cancer 20100316 |
| Oxaliplatin, irinotecan and capecitabine as first-line therapy in metastatic colorectal cancer (mCRC): a dose-finding study and pharmacogenomic analysis. | British journal of cancer 20100316 |
| Simple liquid chromatography method for the quantification of irinotecan and SN38 in sheep plasma: application to in vivo pharmacokinetics after pulmonary artery chemoembolization using drug eluting beads. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100315 |
| Mechanisms of resistance to anti-EGFR monoclonal antibody treatment in metastatic colorectal cancer. | World journal of gastroenterology 20100314 |
| Loss of PTEN expression predicts resistance to EGFR-targeted monoclonal antibodies in patients with metastatic colorectal cancer. | British journal of cancer 20100302 |
| An explorative randomised phase II study of sequential chemotherapy in advanced upper gastrointestinal cancer. | Medical oncology (Northwood, London, England) 20100301 |
| Clinical significance of ABCB1 genotyping in oncology. | Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20100301 |
| Stability of irinotecan-loaded drug eluting beads (DC Bead) used for transarterial chemoembolization. | Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20100301 |
| N0332 phase 2 trial of weekly irinotecan hydrochloride and docetaxel in refractory metastatic breast cancer: a North Central Cancer Treatment Group (NCCTG) Trial. | Annals of oncology : official journal of the European Society for Medical Oncology 20100301 |
| Genotoxicity of irinotecan and its modulation by vitamins A, C and E in human lymphocytes from healthy individuals and cancer patients. | Toxicology in vitro : an international journal published in association with BIBRA 20100301 |
| Phase I study of irinotecan and doxifluridine for metastatic colorectal cancer focusing on the UGT1A1*28 polymorphism. | Cancer science 20100301 |
| Phase 2 study of irinotecan and paclitaxel in patients with recurrent or refractory small cell lung cancer. | Cancer 20100301 |
| Pharmacogenomic and pharmacoproteomic studies of cetuximab in metastatic colorectal cancer: biomarker analysis of a phase I dose-escalation study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100301 |
| Older versus younger patients with metastatic adenocarcinoma of the esophagus, gastroesophageal junction, and stomach: a pooled analysis of eight consecutive North Central Cancer Treatment Group (NCCTG) trials. | International journal of oncology 20100301 |
| Tumor invasion after treatment of glioblastoma with bevacizumab: radiographic and pathologic correlation in humans and mice. | Neuro-oncology 20100301 |
| Lestaurtinib enhances the antitumor efficacy of chemotherapy in murine xenograft models of neuroblastoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100301 |
| In vivo bioassay to detect irinotecan-stabilized DNA/topoisomerase I complexes in rats. | Biotechnology journal 20100301 |
| An overview of the recent progress in irinotecan pharmacogenetics. | Pharmacogenomics 20100301 |
| [A case of small cell lung cancer (extensive disease) with liver metastasis acquiring stable disease by hepatic arterial infusion chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100301 |
| [A case of effective chemotherapy using S-1 and CPT-11 following chemoradiotherapy with UFT and Leucovorin for unresectable advanced sigmoid colon cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100301 |
| [A case of sigmoid colon cancer with lymphangitis carcinomatosa successfully treated with chemotherapies including molecular targeting drugs]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100301 |
| Tumor growth rate determines the timing of optimal chronomodulated treatment schedules. | PLoS computational biology 20100301 |
| Assessment of cyto/genotoxicity of irinotecan in v79 cells using the comet, micronucleus, and chromosome aberration assay. | Arhiv za higijenu rada i toksikologiju 20100301 |
| Establishment and characterization of multidrug-resistant gastric cancer cell lines. | Anticancer research 20100301 |
| Kinetics and regional specificity of irinotecan-induced gene expression in the gastrointestinal tract. | Toxicology 20100227 |
| Diffusion magnetic resonance imaging detects pathologically confirmed, nonenhancing tumor progression in a patient with recurrent glioblastoma receiving bevacizumab. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100220 |
| Treatment options for small cell lung cancer - do we have more choice? | British journal of cancer 20100216 |
| Activating K-Ras mutations outwith 'hotspot' codons in sporadic colorectal tumours - implications for personalised cancer medicine. | British journal of cancer 20100216 |
| Efficacy of ST1968 (namitecan) on a topotecan-resistant squamous cell carcinoma. | Biochemical pharmacology 20100215 |
| Relations between strain and gender dependencies of irinotecan toxicity and UGT1A1, CES2 and TOP1 expressions in mice. | Toxicology letters 20100215 |
| Reversal of established lupus nephritis and prolonged survival of New Zealand black x New Zealand white mice treated with the topoisomerase I inhibitor irinotecan. | Journal of immunology (Baltimore, Md. : 1950) 20100215 |
| Genotype-driven phase I study of irinotecan administered in combination with fluorouracil/leucovorin in patients with metastatic colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100210 |
| Interleukin-21 can efficiently restore impaired antibody-dependent cell-mediated cytotoxicity in patients with oesophageal squamous cell carcinoma. | British journal of cancer 20100202 |
| Phase II trial of mapatumumab, a fully human agonistic monoclonal antibody that targets and activates the tumour necrosis factor apoptosis-inducing ligand receptor-1 (TRAIL-R1), in patients with refractory colorectal cancer. | British journal of cancer 20100202 |
| Randomised, non-comparative phase II study of weekly docetaxel with cisplatin and 5-fluorouracil or with capecitabine in oesophagogastric cancer: the AGITG ATTAX trial. | British journal of cancer 20100202 |
| Cetuximab plus oxaliplatin/leucovorin/5-fluorouracil in first-line metastatic gastric cancer: a phase II study of the Arbeitsgemeinschaft Internistische Onkologie (AIO). | British journal of cancer 20100202 |
| Esophageal ulcer in a patient who received bevacizumab. | Investigational new drugs 20100201 |
| Effects of bevacizumab on plasma concentration of irinotecan and its metabolites in advanced colorectal cancer patients receiving FOLFIRI with bevacizumab as second-line chemotherapy. | Cancer chemotherapy and pharmacology 20100201 |
| Effect of rifampin on the pharmacokinetics of Axitinib (AG-013736) in Japanese and Caucasian healthy volunteers. | Cancer chemotherapy and pharmacology 20100201 |
| Primary gliosarcoma: key clinical and pathologic distinctions from glioblastoma with implications as a unique oncologic entity. | Journal of neuro-oncology 20100201 |
| Predictive factors for the efficacy of cetuximab plus chemotherapy as salvage therapy in metastatic gastric cancer patients. | Cancer chemotherapy and pharmacology 20100201 |
| A prospective monitoring of fatal serious adverse events (SAEs) in a Dutch Colorectal Cancer Group (DCCG) phase III trial (CAIRO) in patients with advanced colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20100201 |
| Dynamic monitoring the TCR CDR3 spectratypes in patients with metastatic CRC treated with a combination of bevacizumab, irinotecan, fluorouracil, and leucovorin. | Cancer immunology, immunotherapy : CII 20100201 |
| Extended-schedule dose-dense temozolomide in refractory gliomas. | Journal of neuro-oncology 20100201 |
| Feasibility and efficacy of capecitabine and FOLFIRI in patients aged 65 years and older with advanced colorectal cancer: a retrospective analysis. | Journal of cancer research and clinical oncology 20100201 |
| A phase II study of a combined biweekly irinotecan and monthly cisplatin treatment for metastatic or recurrent gastric cancer. | American journal of clinical oncology 20100201 |
| Phase II study of paclitaxel and irinotecan with intercalated gefitinib in patients with advanced non-small-cell lung cancer. | American journal of clinical oncology 20100201 |
| Docetaxel-ST1481 sequence exerts a potent cytotoxic activity on hormone-resistant prostate cancer cells by reducing drug resistance-related gene expression. | The Prostate 20100201 |
| Personalized medicine: factors influencing reimbursement. | Health policy (Amsterdam, Netherlands) 20100201 |
| Functional characterization of multidrug resistance-associated protein 3 (mrp3/abcc3) in the basolateral efflux of glucuronide conjugates in the mouse small intestine. | The Journal of pharmacology and experimental therapeutics 20100201 |
| Late recurrence and second primary malignancy among 139 patients with germ cell tumors: long-term outcome of the disease in a single-center experience. | Japanese journal of clinical oncology 20100201 |
| The effect of ethanol on oral cocaine pharmacokinetics reveals an unrecognized class of ethanol-mediated drug interactions. | Drug metabolism and disposition: the biological fate of chemicals 20100201 |
| Rapid UGT1A1 (TA)(n) genotyping by high resolution melting curve analysis for Gilbert's syndrome diagnosis. | Clinica chimica acta; international journal of clinical chemistry 20100201 |
| K-Ras and MSI: potential markers of both patient prognosis and treatment efficacy. | Annals of surgical oncology 20100201 |
| Irinotecan and mismatch repair deficiency. | Annals of oncology : official journal of the European Society for Medical Oncology 20100201 |
| Antitumour activity of NK012, SN-38-incorporating polymeric micelles, in hypovascular orthotopic pancreatic tumour. | European journal of cancer (Oxford, England : 1990) 20100201 |
| Tranilast strongly sensitizes pancreatic cancer cells to gemcitabine via decreasing protein expression of ribonucleotide reductase 1. | International journal of oncology 20100201 |
| Gilbert-Meulengracht's syndrome and pharmacogenetics: is jaundice just the tip of the iceberg? | Drug metabolism reviews 20100201 |
| [Prerequisites to the administration and prevention of adverse effects of chemotherapy in colorectal cancer]. | Bulletin du cancer 20100201 |
| Coexpression of biological key modulators in primary colorectal carcinomas and related metastatic sites: implications for treatment with cetuximab. | Bulletin du cancer 20100201 |
| First-line systemic chemotherapy in the treatment of advanced non-small cell lung cancer: a systematic review. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20100201 |
| [Chemotherapy-induced myelosuppression and treatment efficacy in limited-stage disease small cell lung cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100201 |
| [A case of early poorly-differentiated neuroendocrine carcinoma of stomach]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100201 |
| [Clinical study of irinotecan plus cisplatin for advanced non-small cell lung cancer]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20100201 |
| Randomized phase II trial of paclitaxel plus carboplatin therapy versus irinotecan plus cisplatin therapy as first-line chemotherapy for clear cell adenocarcinoma of the ovary: a JGOG study. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20100201 |
| Cost-effectiveness of oxaliplatin in the adjuvant treatment of colon cancer in Canada. | Current oncology (Toronto, Ont.) 20100201 |
| [A case of dermatomyositis becoming symptomatic after recurrence of small cell lung cancer]. | Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20100201 |
| [Clinical features of patients with brain metastasis from testicular germ cell tumor]. | Hinyokika kiyo. Acta urologica Japonica 20100201 |
| The role of anti-epidermal growth factor receptor monoclonal antibody monotherapy in the treatment of metastatic colorectal cancer. | Cancer treatment reviews 20100201 |
| Irinotecan hydrochloride (CPT-11) in dialysis patients with gastrointestinal cancer. | Acta medica Okayama 20100201 |
| Triplet chemotherapy with cisplatin, docetaxel, and irinotecan for patients with recurrent or refractory non-small cell lung cancer. | Acta medica Okayama 20100201 |
| Recent strategy for the management of advanced testicular cancer. | International journal of urology : official journal of the Japanese Urological Association 20100201 |
| Surgical downstaging and neo-adjuvant therapy in metastatic colorectal carcinoma with irinotecan drug-eluting beads: a multi-institutional study. | HPB : the official journal of the International Hepato Pancreato Biliary Association 20100201 |
| Perioperative chemotherapy with bevacizumab and liver resection for colorectal cancer liver metastasis. | HPB : the official journal of the International Hepato Pancreato Biliary Association 20100201 |
| Novel amelanotic and melanotic cell lines NM78-AM and NM78-MM derived from a human oral malignant melanoma. | Human cell 20100201 |
| Differential contribution to neuroendocrine tumorigenesis of parallel egfr signaling in cancer cells and pericytes. | Genes & cancer 20100201 |
| Pharmacogenetics of irinotecan: An ethnicity-based prediction of irinotecan adverse events. | World journal of gastrointestinal surgery 20100127 |
| Phase II trial of infusional fluorouracil, irinotecan, and bevacizumab for metastatic colorectal cancer: efficacy and circulating angiogenic biomarkers associated with therapeutic resistance. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100120 |
| C20orf20 (MRG-binding protein) as a potential therapeutic target for colorectal cancer. | British journal of cancer 20100119 |
| Defining patient outcomes in stage IV colorectal cancer: a prospective study with baseline stratification according to disease resectability status. | British journal of cancer 20100119 |
| Individualizing dosing of irinotecan. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100115 |
| A CYP3A4 phenotype-based dosing algorithm for individualized treatment of irinotecan. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100115 |
| Antitumor effect of NK012, a 7-ethyl-10-hydroxycamptothecin-incorporating polymeric micelle, on U87MG orthotopic glioblastoma in mice compared with irinotecan hydrochloride in combination with bevacizumab. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100115 |
| Bevacizumab and irinotecan for recurrent oligodendroglial tumors. | Neurology 20100112 |
| Costs of managing adverse events in the treatment of first-line metastatic renal cell carcinoma: bevacizumab in combination with interferon-alpha2a compared with sunitinib. | British journal of cancer 20100105 |
| Sorafenib in patients with advanced biliary tract carcinoma: a phase II trial. | British journal of cancer 20100105 |
| PTEN status in advanced colorectal cancer treated with cetuximab. | British journal of cancer 20100105 |
| Prognostic effect of activated EGFR expression in human colon carcinomas: comparison with EGFR status. | British journal of cancer 20100105 |
| Biomarkers of angiogenesis and their role in the development of VEGF inhibitors. | British journal of cancer 20100105 |
| A water soluble prodrug of a novel camptothecin analog is efficacious against breast cancer resistance protein-expressing tumor xenografts. | Cancer chemotherapy and pharmacology 20100101 |
| Tyrosine kinase inhibitors and multidrug resistance proteins: interactions and biological consequences. | Cancer chemotherapy and pharmacology 20100101 |
| Capped-dose mitomycin C: a pooled safety analysis from three prospective clinical trials. | Cancer chemotherapy and pharmacology 20100101 |
| Polar lipid remodeling and increased sulfatide expression are associated with the glioma therapeutic candidates, wild type p53 elevation and the topoisomerase-1 inhibitor, irinotecan. | Glycoconjugate journal 20100101 |
| A randomized multicenter phase II study comparing capecitabine with irinotecan or cisplatin in metastatic adenocarcinoma of the stomach or esophagogastric junction. | Annals of oncology : official journal of the European Society for Medical Oncology 20100101 |
| Combination intraperitoneal chemotherapy is superior to mitomycin C or oxaliplatin for colorectal carcinomatosis in vivo. | Annals of surgical oncology 20100101 |
| Long-term outcome of chemotherapy for advanced testicular and extragonadal germ cell tumors: a single-center 27-year experience. | Japanese journal of clinical oncology 20100101 |
| A phase II study of irinotecan and capecitabine for patients with unresectable liver-only metastases from colorectal cancer. | Japanese journal of clinical oncology 20100101 |
| Attenuation of cytogenetic effects by erythropoietin in human lymphocytes in vitro and P388 ascites tumor cells in vivo treated with irinotecan (CPT-11). | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101 |
| Pharmacogenetics of phase I and phase II drug metabolism. | Current pharmaceutical design 20100101 |
| Role of pemetrexed and platinums combination in patients with non-small cell lung cancer. | Current drug targets 20100101 |
| Irinotecan and its active metabolite, SN-38: review of bioanalytical methods and recent update from clinical pharmacology perspectives. | Biomedical chromatography : BMC 20100101 |
| Endophytic fungal strains of Fusarium solani, from Apodytes dimidiata E. Mey. ex Arn (Icacinaceae) produce camptothecin, 10-hydroxycamptothecin and 9-methoxycamptothecin. | Phytochemistry 20100101 |
| No effect of irinotecan in patients with resistant desmoplastic small round cell tumor. | Pediatric blood & cancer 20100101 |
| An animal model for chemotherapy-associated steatohepatitis and its prevention by the oral administration of fatty acid bile acid conjugate. | Cancer 20100101 |
| Controversies in the treatment of advanced stages of small cell lung cancer. | Frontiers of radiation therapy and oncology 20100101 |
| CpG island methylation of BNIP3 predicts resistance against S-1/CPT-11 combined therapy in colorectal cancer patients. | Oncology reports 20100101 |
| Bevacizumab plus irinotecan-based therapy in metastatic colorectal cancer patients previously treated with oxaliplatin-based regimens. | Cancer investigation 20100101 |
| Palliative treatment of unresectable metastatic colorectal cancer. | Expert opinion on pharmacotherapy 20100101 |
| Colorectal cancer in Mexico: should a middle income country invest in screening or in treatment? | The European journal of health economics : HEPAC : health economics in prevention and care 20100101 |
| Methods for evaluating effects of an irinotecan + 5-fluorouracil/leucovorin (IFL) regimen in an orthotopic metastatic colorectal cancer model utilizing in vivo bioluminescence imaging. | Methods in molecular biology (Clifton, N.J.) 20100101 |
| Targeting the epidermal growth factor receptor in epithelial ovarian cancer: current knowledge and future challenges. | Journal of oncology 20100101 |
| Analytical strategies for characterizing chemotherapy diffusion with patient-level population-based data. | Applied health economics and health policy 20100101 |
| Treatment of extensive-stage small cell lung carcinoma: current status and future prospects. | The European respiratory journal 20100101 |
| Evaluation of biodistribution and safety of adenovirus vector containing MDR1 in mice. | Journal of experimental & clinical cancer research : CR 20100101 |
| The role of monoclonal antibody in combination with first-line chemotherapy in Asian patients with advanced non-small cell lung cancer. | Yonsei medical journal 20100101 |
| The preclinical pharmacology and therapeutic activity of the novel CHK1 inhibitor SAR-020106. | Molecular cancer therapeutics 20100101 |
| Treatment for recurrent ovarian cancer-at first relapse. | Journal of oncology 20100101 |
| The evolving role of monoclonal antibodies in colorectal cancer: early presumptions and impact on clinical trial development. | The oncologist 20100101 |
| Combination of bilateral metal stenting and trans-stent photodynamic therapy for palliative treatment of hilar cholangiocarcinoma. | Zeitschrift fur Gastroenterologie 20100101 |
| [Retrospective analysis of generalized chemotherapy for unresectable advanced gastric cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100101 |
| [A case of advanced gastric cancer with a complete response to S-1 plus CPT-11 chemotherapy for eight years]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100101 |
| [Successful treatment with S-1 + CPT-11 for hepatic metastasis from gastric cancer--a case report]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100101 |
| [S-1 + CPT-11 combination therapy with continuing 30-month CR in a recurrent gastric cancer with para-aortic lymph node metastasis in adjuvant chemotherapy with S-1--a case report]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100101 |
| [A case of S-1-resistant gastric cancer with multiple bone metastases and disseminated intravascular coagulation--effective treatment by combined chemotherapy with CDDP and CPT-11]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100101 |
| [Pulmonary embolism during palliative chemotherapy including cetuximab for metastatic colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100101 |
| [A case of advanced rectal cancer with liver and lung metastasis showing a complete response by neo-adjuvant FOLFOX4 chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100101 |
| [Liver metastasis from sigmoid colon cancer showed a complete response to S-1 after recurrence with FOLFOX6 treatment]. | Gan to kagaku ryoho. Cancer & chemotherapy 20100101 |
| Complete response to FOLFOX4 therapy in a patient with advanced urothelial cancer: a case report. | Journal of hematology & oncology 20100101 |
| Regulation of UGT1A1 and HNF1 transcription factor gene expression by DNA methylation in colon cancer cells. | BMC molecular biology 20100101 |
| Cancer cell sensitivity to bortezomib is associated with survivin expression and p53 status but not cancer cell types. | Journal of experimental & clinical cancer research : CR 20100101 |
| [Oxaliplatin and leucovorin plus fluorouracil versus irinotecan and leucovorin plus fluorouracil combination chemotherapy as a first-line treatment in patients with metastatic or recurred gastric adenocarcinoma]. | The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20100101 |
| Evolution of capecitabine dosing in colorectal cancer. | Clinical colorectal cancer 20100101 |
| [Neuroendocrine differentiation in adenocarcinoma of the prostate during hormonal treatment : a case report]. | Hinyokika kiyo. Acta urologica Japonica 20100101 |
| Usefulness of staging laparoscopy for advanced gastric cancer. | Surgery today 20100101 |
| Bevacizumab: in previously treated glioblastoma. | Drugs 20100101 |
| Colorectal cancer: response to sunitinib in a heavily pretreated colorectal cancer patient. | Anti-cancer drugs 20100101 |
| Analysis of compound synergy in high-throughput cellular screens by population-based lifetime modeling. | PloS one 20100101 |
| BCNU for recurrent glioblastoma multiforme: efficacy, toxicity and prognostic factors. | BMC cancer 20100101 |
| An evolved ribosome-inactivating protein targets and kills human melanoma cells in vitro and in vivo. | Molecular cancer 20100101 |
| Targeted therapy in ovarian cancer. | Journal of oncology 20100101 |
| TAp73 is one of the genes responsible for the lack of response to chemotherapy depending on B-Raf mutational status. | Journal of translational medicine 20100101 |
| From basic research to clinical development of MEK1/2 inhibitors for cancer therapy. | Journal of hematology & oncology 20100101 |
| Cloning and comparative analyses of the zebrafish Ugt repertoire reveal its evolutionary diversity. | PloS one 20100101 |
| Preliminary experience of cetuximab in the treatment of advanced-stage biliary tract cancer. | Onkologie 20100101 |
| Paclitaxel/carboplatin/etoposide versus gemcitabine/irinotecan in the first-line treatment of patients with carcinoma of unknown primary site: a randomized, phase III Sarah Cannon Oncology Research Consortium Trial. | Cancer journal (Sudbury, Mass.) 20100101 |
| Neo-adjuvant chemo-radiation of rectal cancer with volumetric modulated arc therapy: summary of technical and dosimetric features and early clinical experience. | Radiation oncology (London, England) 20100101 |
| [Does bevacizumab have a protective effect on hepatotoxicity induced by chemotherapy?]. | Journal de chirurgie 20100101 |
| [Chemotherapy's hepatotoxicity: what is the impact on surgery?]. | Journal de chirurgie 20100101 |
| Bladder metastases of appendiceal mucinous adenocarcinoma: a case presentation. | BMC cancer 20100101 |
| Increased shedding of HU177 correlates with worse prognosis in primary melanoma. | Journal of translational medicine 20100101 |
| BRCA1 as a Therapeutic Target in Sporadic Epithelial Ovarian Cancer. | Journal of oncology 20100101 |
| Mutations in epidermal growth factor receptor and K-ras in Chinese patients with colorectal cancer. | BMC medical genetics 20100101 |
| Gene expression profile of colon cancer cell lines treated with SN-38. | Chemotherapy 20100101 |
| Association between gefitinib and hemorrhagic cystitis and severely contracted bladder: a case report. | BMC urology 20100101 |
| Pregnane X Receptor (PXR) expression in colorectal cancer cells restricts irinotecan chemosensitivity through enhanced SN-38 glucuronidation. | Molecular cancer 20100101 |
| Pharmacogenetics in oncology: a promising field. | Current pharmaceutical design 20100101 |
| What else in gemcitabine-pretreated advanced pancreatic cancer? An update of second line therapies. | Reviews on recent clinical trials 20100101 |
| Ongoing challenges in drug interaction safety: from exposure to pharmacogenomics. | Drug metabolism and pharmacokinetics 20100101 |
| [Prognostic analysis of patients with liver metastases from colorectal cancer treated with different modes of therapy]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20100101 |
| Molecular mechanisms of resistance to tumour anti-angiogenic strategies. | Journal of oncology 20100101 |
| Temozolomide-induced myelodysplasia. | Advances in hematology 20100101 |
| Modified-irinotecan/fluorouracil/levoleucovorin therapy as ambulatory treatment for metastatic colorectal cancer: results of phase I and II studies. | Clinical drug investigation 20100101 |
| Pro-inflammatory cytokines play a key role in the development of radiotherapy-induced gastrointestinal mucositis. | Radiation oncology (London, England) 20100101 |
| Treatment-related toxicity and supportive care in metastatic colorectal cancer. | The journal of supportive oncology 20100101 |
| Pharmacogenomics and personalized medicine: lost in translation? | Genome medicine 20100101 |
| RBC and WBC fatty acid composition following consumption of an omega 3 supplement: lessons for future clinical trials. | Lipids in health and disease 20100101 |
| Recent advances in gastrointestinal oncology--updates and insights from the 2009 annual meeting of the American society of clinical oncology. | Journal of hematology & oncology 20100101 |
| Safety margin in irradiation of colorectal liver metastases: assessment of the control dose of micrometastases. | Radiation oncology (London, England) 20100101 |
| Herbal interactions with anticancer drugs: mechanistic and clinical considerations. | Current medicinal chemistry 20100101 |
| Hypersensitivity reaction and acute immune-mediated thrombocytopenia from oxaliplatin: two case reports and a review of the literature. | Journal of hematology & oncology 20100101 |
| Cancer-associated thrombosis. | The open cardiovascular medicine journal 20100101 |
| Cancer-drug associations: a complex system. | PloS one 20100101 |
| Angiogenesis and lymphangiogenesis of gastric cancer. | Journal of oncology 20100101 |
| The UGT1A1*28 genotype and the toxicity of low-dose irinotecan in patients with advanced lung cancer. | Oncology research 20100101 |
| Progress on antiangiogenic therapy for patients with malignant glioma. | Journal of oncology 20100101 |
| Molecular mechanisms of acquired resistance to tyrosine kinase targeted therapy. | Molecular cancer 20100101 |
| Lack of evidence for KRAS oncogenic mutations in triple-negative breast cancer. | BMC cancer 20100101 |
| Phase II Study of Biweekly Pemetrexed Plus Irinotecan as Second-Line Therapy for Metastatic Colorectal Cancer. | Journal of oncology 20100101 |
| Molecular targeted therapies in head and neck cancer--an update of recent developments-. | Head & neck oncology 20100101 |
| Targeting Hsp90 with small molecule inhibitors induces the over-expression of the anti-apoptotic molecule, survivin, in human A549, HONE-1 and HT-29 cancer cells. | Molecular cancer 20100101 |
| HSP90 inhibitor, celastrol, arrests human monocytic leukemia cell U937 at G0/G1 in thiol-containing agents reversible way. | Molecular cancer 20100101 |
| Epidermal growth factor receptor gene copy number in 101 advanced colorectal cancer patients treated with chemotherapy plus cetuximab. | Journal of translational medicine 20100101 |
| Cell-specific expression of tryptophan decarboxylase and 10-hydroxygeraniol oxidoreductase, key genes involved in camptothecin biosynthesis in Camptotheca acuminata Decne (Nyssaceae). | BMC plant biology 20100101 |
| Screening mammography use and chemotherapy among female stage II colon cancer patients: a retrospective cohort study. | BMC health services research 20100101 |
| Cetuximab given every 2 weeks plus irinotecan is an active and safe option for previously treated patients with metastatic colorectal cancer. | Chemotherapy 20100101 |
| Antiangiogenic therapy and mechanisms of tumor resistance in malignant glioma. | Journal of oncology 20100101 |
| Molecular therapeutic targets for glioma angiogenesis. | Journal of oncology 20100101 |
| Quantitative methodology using CT for predicting survival in patients with metastatic colorectal carcinoma: a pilot study. | Clinical imaging 20100101 |
| [Specific treatment situations in metastatic colorectal cancer]. | Onkologie 20100101 |
| Tumor angiogenesis: insights and innovations. | Journal of oncology 20100101 |
| Architectural heterogeneity in tumors caused by differentiation alters intratumoral drug distribution and affects therapeutic synergy of antiangiogenic organoselenium compound. | Journal of oncology 20100101 |
| Peptide-mediated liposomal drug delivery system targeting tumor blood vessels in anticancer therapy. | Journal of oncology 20100101 |
| Emergence of rationally designed therapeutic strategies for breast cancer targeting DNA repair mechanisms. | Breast cancer research : BCR 20100101 |
| Lack of relationship between TIMP-1 tumour cell immunoreactivity, treatment efficacy and prognosis in patients with advanced epithelial ovarian cancer. | BMC cancer 20100101 |
| Epidermal growth factor receptor and K-RAS status in two cohorts of squamous cell carcinomas. | BMC cancer 20100101 |
| Is monthly retreatment with intravitreal bevacizumab (Avastin) necessary in neovascular age-related macular degeneration? | Clinical ophthalmology (Auckland, N.Z.) 20100101 |
| Combination therapy with docetaxel and S-1 as a first-line treatment in patients with advanced or recurrent gastric cancer: a retrospective analysis. | World journal of surgical oncology 20100101 |
| Prospective randomized trial evaluating mandatory second look surgery with HIPEC and CRS vs. standard of care in patients at high risk of developing colorectal peritoneal metastases. | Trials 20100101 |
| Magnitude of benefit of the addition of bevacizumab to first-line chemotherapy for metastatic colorectal cancer: meta-analysis of randomized clinical trials. | Journal of experimental & clinical cancer research : CR 20100101 |
| Radiobiological restrictions and tolerance doses of repeated single-fraction hdr-irradiation of intersecting small liver volumes for recurrent hepatic metastases. | Radiation oncology (London, England) 20100101 |
| Vascular endothelial growth factor-related pathways in hemato-lymphoid malignancies. | Journal of oncology 20100101 |
| The clinical application of UGT1A1 pharmacogenetic testing: gene-environment interactions. | Human genomics 20100101 |
| Metastatic colorectal cancer: from improved survival to potential cure. | Oncology 20100101 |
| Strategic options on behalf of patients with metastatic colorectal cancer: mass tumor murder versus serial tumor killing. | Onkologie 20100101 |
| Oxaliplatin, irinotecan and capecitabine (OCX) for first-line treatment of advanced/metastatic colorectal cancer: a phase I trial (SAKK 41/03). | Onkologie 20100101 |
| Meta-analysis of chemotherapy with irinotecan or oxaliplatin-involved regimen for untreated metastatic advanced colorectal cancer. | Oncology research 20100101 |
| Effects of bevacizumab plus irinotecan on response and survival in patients with recurrent malignant glioma: a systematic review and survival-gain analysis. | BMC cancer 20100101 |
| The distribution of the therapeutic monoclonal antibodies cetuximab and trastuzumab within solid tumors. | BMC cancer 20100101 |
| Primary appendiceal mucinous adenocarcinoma alongside with situs inversus totalis: a unique clinical case. | World journal of surgical oncology 20100101 |
| SNAI2/Slug promotes growth and invasion in human gliomas. | BMC cancer 20100101 |
| Expression of growth factor receptors and targeting of EGFR in cholangiocarcinoma cell lines. | BMC cancer 20100101 |
| Clinical trials with anti-angiogenic agents in hematological malignancies. | Journal of angiogenesis research 20100101 |
| Helical tomotherapy with concurrent capecitabine for the treatment of inoperable pancreatic cancer. | Radiation oncology (London, England) 20100101 |
| Putative contribution of CD56 positive cells in cetuximab treatment efficacy in first-line metastatic colorectal cancer patients. | BMC cancer 20100101 |
| Efficacy of combination treatment and influence of schedule with irinotecan and amrubicin in human lung carcinoma cells in vivo and in vitro. | Biological & pharmaceutical bulletin 20100101 |
| The role of radiotherapy in multimodal treatment of pancreatic carcinoma. | Radiation oncology (London, England) 20100101 |
| New treatment options in the management of glioblastoma multiforme: a focus on bevacizumab. | OncoTargets and therapy 20100101 |
| Anti-angiogenesis therapies: their potential in cancer management. | OncoTargets and therapy 20100101 |
| Clinical relevance of KRAS in human cancers. | Journal of biomedicine & biotechnology 20100101 |
| New targeted molecular therapies for dedifferentiated thyroid cancer. | Journal of oncology 20100101 |
| Molecular and clinical aspects of targeting the VEGF pathway in tumors. | Journal of oncology 20100101 |
| Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells. | BMC cancer 20100101 |
| Is Platinum Present in Blood and Urine from Treatment Givers during Hyperthermic Intraperitoneal Chemotherapy? | Journal of oncology 20100101 |
| Successful treatment of recurrent small bowel adenocarcinoma by cytoreductive surgery and chemotherapy: a case report and review of the literature. | Journal of medical case reports 20100101 |
| Mitomycin C and UFT/leucovorin as salvage treatment in patients with advanced colorectal cancer. | Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20100101 |
| Irinotecan and cisplatin vs. cyclophosphamide, doxorubicin, and vincristine as second-line treatment after platinum and etoposide in small-cell lung cancer. | Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20100101 |
| GU81, a VEGFR2 antagonist peptoid, enhances the anti-tumor activity of doxorubicin in the murine MMTV-PyMT transgenic model of breast cancer. | BMC cancer 20100101 |
| Angiogenesis inhibitors in the treatment of prostate cancer. | Journal of hematology & oncology 20100101 |
| 5-FU-hydrogel inhibits colorectal peritoneal carcinomatosis and tumor growth in mice. | BMC cancer 20100101 |
| Regulation of the Aurora-A gene following topoisomerase I inhibition: implication of the Myc transcription factor. | Molecular cancer 20100101 |
| Mutations in the WTX-gene are found in some high-grade microsatellite instable (MSI-H) colorectal cancers. | BMC cancer 20100101 |
| Sorafenib after combination therapy with gemcitabine plus doxorubicine in patients with sarcomatoid renal cell carcinoma: a prospective evaluation. | European journal of medical research 20100101 |
| Leveraging learning from a phase III colorectal cancer clinical trial: outcomes, methodology, meta-analysis and pharmacogenetics. | Transactions of the American Clinical and Climatological Association 20100101 |
| r84, a novel therapeutic antibody against mouse and human VEGF with potent anti-tumor activity and limited toxicity induction. | PloS one 20100101 |
| Cellular apoptosis susceptibility (CSE1L/CAS) protein in cancer metastasis and chemotherapeutic drug-induced apoptosis. | Journal of experimental & clinical cancer research : CR 20100101 |
| Trends in cancer immunotherapy. | Clinical Medicine Insights. Oncology 20100101 |
| LY294002 may overcome 5-FU resistance via down-regulation of activated p-AKT in Epstein-Barr virus-positive gastric cancer cells. | BMC cancer 20100101 |
| The challenge of metastatic colorectal cancer. | Clinical Medicine Insights. Oncology 20100101 |
| Preclinical pharmacology of BA-TPQ, a novel synthetic iminoquinone anticancer agent. | Marine drugs 20100101 |
| Biological characteristics and treatment outcomes of metastatic or recurrent neuroendocrine tumors: tumor grade and metastatic site are important for treatment strategy. | BMC cancer 20100101 |
| Detecting acute neurotoxicity during platinum chemotherapy by neurophysiological assessment of motor nerve hyperexcitability. | BMC cancer 20100101 |
| A multicenter phase II trial with irinotecan plus oxaliplatin as first-line treatment for inoperable/metastatic cancer of the biliary tract. | Oncology 20100101 |
| Treatment of colorectal cancer with and without bevacizumab: a phase III study. | Oncology 20100101 |
| Anti-tumor effects of CIK combined with oxaliplatin in human oxaliplatin-resistant gastric cancer cells in vivo and in vitro. | Journal of experimental & clinical cancer research : CR 20100101 |
| Tumor growth and angiogenesis is impaired in CIB1 knockout mice. | Journal of angiogenesis research 20100101 |
| The role of adjuvant pelvic radiotherapy in rectal cancer with synchronous liver metastasis: a retrospective study. | Radiation oncology (London, England) 20100101 |
| The Met oncogene and basal-like breast cancer: another culprit to watch out for? | Breast cancer research : BCR 20100101 |
| Antibody targeting of cathepsin S inhibits angiogenesis and synergistically enhances anti-VEGF. | PloS one 20100101 |
| HSV Recombinant Vectors for Gene Therapy. | The open virology journal 20100101 |
| Fluorescence in situ hybridization in combination with the comet assay and micronucleus test in genetic toxicology. | Molecular cytogenetics 20100101 |
| [Pharmacogenomics and chemotherapy]. | Recenti progressi in medicina 20100101 |
| Effects of genetic polymorphisms in the ABCB1 gene on clinical outcomes in patients with gastric cancer treated by second-line chemotherapy. | Asian Pacific journal of cancer prevention : APJCP 20100101 |
| Co-expression of nuclear and cytoplasmic HMGB1 is inversely associated with infiltration of CD45RO+ T cells and prognosis in patients with stage IIIB colon cancer. | BMC cancer 20100101 |
| Current and emerging therapies for the treatment of pancreatic cancer. | OncoTargets and therapy 20100101 |
| Temozolomide in malignant glioma. | OncoTargets and therapy 20100101 |
| Pharmacogenetics and pharmacogenomics: practical applications in routine medical practice. | Genome medicine 20100101 |
| Molecular and other novel advances in treatment of metastatic epithelial and medullary thyroid cancers. | Journal of oncology 20100101 |
| Intravenous administration of anti-vascular endothelial growth factor humanized monoclonal antibody bevacizumab improves articular cartilage repair. | Arthritis research & therapy 20100101 |
| Clinicopathological analysis of recurrence patterns and prognostic factors for survival after hepatectomy for colorectal liver metastasis. | BMC surgery 20100101 |
| Hypersensitivity reactions associated with platinum antineoplastic agents: a systematic review. | Metal-based drugs 20100101 |
| Safety and pharmacokinetics of novel selective vascular endothelial growth factor receptor-2 inhibitor YN968D1 in patients with advanced malignancies. | BMC cancer 20100101 |
| Chemotherapy in Ewing's sarcoma. | Indian journal of orthopaedics 20100101 |
| Population-based patterns of care in the first-line treatment of patients with advanced esophagogastric adenocarcinoma in Germany. | Onkologie 20100101 |
| Overview of cellular immunotherapy for patients with glioblastoma. | Clinical & developmental immunology 20100101 |
| 'Poker' association of weekly alternating 5-fluorouracil, irinotecan, bevacizumab and oxaliplatin (FIr-B/FOx) in first line treatment of metastatic colorectal cancer: a phase II study. | BMC cancer 20100101 |
| Preferential antitumor effect of the Src inhibitor dasatinib associated with a decreased proportion of aldehyde dehydrogenase 1-positive cells in breast cancer cells of the basal B subtype. | BMC cancer 20100101 |
| Complete response in gallbladder cancer to erlotinib plus gemcitabine does not require mutation of the epidermal growth factor receptor gene: a case report. | BMC cancer 20100101 |
| Molecular characterization and response to cetuximab in a patient with refractory squamous cell anal carcinoma. | Tumori 20100101 |
| Highly efficient elimination of colorectal tumor-initiating cells by an EpCAM/CD3-bispecific antibody engaging human T cells. | PloS one 20100101 |
| Context-dependent cell cycle checkpoint abrogation by a novel kinase inhibitor. | PloS one 20100101 |
| Whole-liver radiotherapy for end-stage colorectal cancer patients with massive liver metastases and advanced hepatic dysfunction. | Radiation oncology (London, England) 20100101 |
| Retrospective analyses of cisplatin-based doublet combination chemotherapy in patients with advanced gastric cancer. | BMC cancer 20100101 |
| Treatment options for patients with triple-negative breast cancer. | Journal of hematology & oncology 20100101 |
| Genetic variations in human glutathione transferase enzymes: significance for pharmacology and toxicology. | Human genomics and proteomics : HGP 20100101 |
| A novel antiangiogenic peptide derived from hepatocyte growth factor inhibits neovascularization in vitro and in vivo. | Molecular vision 20100101 |
| Long-term complete response of unresectable liver metastases from colorectal cancer. | Hepato-gastroenterology 20100101 |
| Panitumumab: the evidence for its use in the treatment of metastatic colorectal cancer. | Core evidence 20100101 |
| Fosaprepitant and aprepitant: an update of the evidence for their place in the prevention of chemotherapy-induced nausea and vomiting. | Core evidence 20100101 |
| Present and future evolution of advanced breast cancer therapy. | Breast cancer research : BCR 20100101 |
| Chemotherapy resistance in metastatic breast cancer: the evolving role of ixabepilone. | Breast cancer research : BCR 20100101 |
| Antiangiogenic activity of 2-deoxy-D-glucose. | PloS one 20100101 |
| Topoisomerase II alpha expression and the benefit of adjuvant chemotherapy for postoperative patients with non-small cell lung cancer. | BMC cancer 20100101 |
| Flavopiridol pharmacogenetics: clinical and functional evidence for the role of SLCO1B1/OATP1B1 in flavopiridol disposition. | PloS one 20100101 |
| Effects of valproic acid on the cell cycle and apoptosis through acetylation of histone and tubulin in a scirrhous gastric cancer cell line. | Journal of experimental & clinical cancer research : CR 20100101 |
| Targeting EGFR/HER2 pathways enhances the antiproliferative effect of gemcitabine in biliary tract and gallbladder carcinomas. | BMC cancer 20100101 |
| Bevacizumab plus irinotecan-based regimens in the treatment of metastatic colorectal cancer. | Oncology 20100101 |
| A randomized phase III study of the docetaxel/carboplatin combination versus docetaxel single-agent as second line treatment for patients with advanced/metastatic non-small cell lung cancer. | BMC cancer 20100101 |
| Thymic large cell neuroendocrine carcinoma: report of a resected case - a case report. | Journal of cardiothoracic surgery 20100101 |
| Effect of erythropoietin, 5-fluorouracil and SN-38 on the growth of DLD-1 cells. | Pharmacological reports : PR 20100101 |
| Treatment of locally advanced carcinomas of head and neck with intensity-modulated radiation therapy (IMRT) in combination with cetuximab and chemotherapy: the REACH protocol. | BMC cancer 20100101 |
| DNA polymerase η protein expression predicts treatment response and survival of metastatic gastric adenocarcinoma patients treated with oxaliplatin-based chemotherapy. | Journal of translational medicine 20100101 |
| The emerging role of nimotuzumab in the treatment of non-small cell lung cancer. | Biologics : targets & therapy 20100101 |
| KRAS analysis in colorectal carcinoma: analytical aspects of Pyrosequencing and allele-specific PCR in clinical practice. | BMC cancer 20100101 |
| Efficacy and safety of irinotecan-based chemotherapy for advanced colorectal cancer outside clinical trials: an observational study. | Onkologie 20100101 |
| Combination treatment with MEK and AKT inhibitors is more effective than each drug alone in human non-small cell lung cancer in vitro and in vivo. | PloS one 20100101 |
| Suppressive effects of vascular endothelial growth factor-B on tumor growth in a mouse model of pancreatic neuroendocrine tumorigenesis. | PloS one 20100101 |
| Targeting the oncogenic protein beta-catenin to enhance chemotherapy outcome against solid human cancers. | Molecular cancer 20100101 |
| Efficacy and safety of endostar combined with chemotherapy in patients with advanced solid tumors. | Asian Pacific journal of cancer prevention : APJCP 20100101 |
| Improving CT prediction of treatment response in patients with metastatic colorectal carcinoma using statistical learning theory. | BMC genomics 20100101 |
| The inefficacy of antiangiogenic therapies. | Journal of angiogenesis research 20100101 |
| Advances in the field of nanooncology. | BMC medicine 20100101 |
| Initial partial response and stable disease according to RECIST indicate similar survival for chemotherapeutical patients with advanced non-small cell lung cancer. | BMC cancer 20100101 |
| VEGFR2 heterogeneity and response to anti-angiogenic low dose metronomic cyclophosphamide treatment. | BMC cancer 20100101 |
| DNA aptamers as molecular probes for colorectal cancer study. | PloS one 20100101 |
| The colorectal cancer disease-specific transcriptome may facilitate the discovery of more biologically and clinically relevant information. | BMC cancer 20100101 |
| Angiogenesis - still a worthwhile target for breast cancer therapy? | Breast cancer research : BCR 20100101 |
| Evaluation of best supportive care and systemic chemotherapy as treatment stratified according to the retrospective peritoneal surface disease severity score (PSDSS) for peritoneal carcinomatosis of colorectal origin. | BMC cancer 20100101 |
| Role of bevacizumab therapy in the management of glioblastoma. | Cancer management and research 20100101 |
| Management of metastatic renal cell carcinoma in patients with poor prognosis. | Cancer management and research 20100101 |
| Cetuximab in the treatment of head and neck cancer: preliminary results outside clinical trials. | Cancer management and research 20100101 |
| Key Role of Human ABC Transporter ABCG2 in Photodynamic Therapy and Photodynamic Diagnosis. | Advances in pharmacological sciences 20100101 |
| Somatic mutation profiles of MSI and MSS colorectal cancer identified by whole exome next generation sequencing and bioinformatics analysis. | PloS one 20100101 |
| CoFactor: Folate Requirement for Optimization of 5-Fluouracil Activity in Anticancer Chemotherapy. | Journal of oncology 20100101 |
| 1, 9-Pyrazoloanthrones downregulate HIF-1α and sensitize cancer cells to cetuximab-mediated anti-EGFR therapy. | PloS one 20100101 |
| A patient with metastatic colon cancer to the liver presenting with cardiac arrest status post receiving combination irinotecan-panitumumab: a case report. | Journal of experimental therapeutics & oncology 20100101 |
| Capecitabine chemotherapy for metastatic colorectal cancer. Chemical structure, combinations and efficacy. | Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20100101 |
| UK Guidelines for the Management of Bone Sarcomas. | Sarcoma 20100101 |
| Cetuximab plus FOLFOX for Patients with Metastatic Colorectal Cancer with Poor Performance Status and/or Severe Tumor-Related Complications. | Case reports in oncology 20100101 |
| Irinotecan as a maintenance therapy for hepatoblastoma: a comment. | Journal of cancer research and therapeutics 20100101 |
| Improvement of oral intake following chemotherapy in gastric cancer patients with an inability to eat. | Oncology 20100101 |
| Immunotherapy of brain cancers: the past, the present, and future directions. | Clinical & developmental immunology 20100101 |
| Complete resection of unresectable liver metastases from colorectal cancer without deterioration of liver function after cetuximab and irinotecan: two case reports. | Hepato-gastroenterology 20100101 |
| Establishment and characterization of irinotecan-resistant human non-small cell lung cancer A549 cells. | Molecular medicine reports 20100101 |
| Cost-effectiveness of UGT1A1*28 genotyping in preventing severe neutropenia following FOLFIRI therapy in colorectal cancer. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20100101 |
| Cetuximab concomitant with second-line radiation therapy in patients with locally advanced recurrent squamous cell head and neck cancer. | Case reports in oncology 20100101 |
| Cutaneous metastasis at a surgical drain site after gastric cancer resection. | Case reports in oncology 20100101 |
| Complete response of a metastatic gastroesophageal adenocarcinoma on irinotecan-based chemotherapy in a dialysis patient. | International journal of nephrology and renovascular disease 20100101 |
| Ayurveda and cancer. | Pharmacognosy research 20100101 |
| Chemotherapy-induced diarrhea: pathophysiology, frequency and guideline-based management. | Therapeutic advances in medical oncology 20100101 |
| The hungry stomach: physiology, disease, and drug development opportunities. | Frontiers in pharmacology 20100101 |
| Nanomedicine formulations for combination therapies. | Nano reviews 20100101 |
| Might salicylate exert benefits against childhood cancer? | Ecancermedicalscience 20100101 |
| The role of funding and policies on innovation in cancer drug development. | Ecancermedicalscience 20100101 |
| Cloning and expression of human vascular endothelial growth factor gene and inhibition of its expression by antisense in prokaryotic system. | Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20100101 |
| KRAS Testing for Anti-EGFR Therapy in Advanced Colorectal Cancer: An Evidence-Based and Economic Analysis. | Ontario health technology assessment series 20100101 |
| En bloc resection for right colon cancer directly invading duodenum or pancreatic head. | Yonsei medical journal 20091231 |
| Colonic cancer in adolescents. A report of three cases. | Rare tumors 20091228 |
| The dual EGFR/HER-2 tyrosine kinase inhibitor lapatinib sensitizes colon and gastric cancer cells to the irinotecan active metabolite SN-38. | International journal of cancer 20091215 |
| Alveolar rhabdomyosarcoma of the extremity and nodal metastasis: Is the in-transit lymphatic system at risk? | Pediatric blood & cancer 20091215 |
| Multicentre phase II studies evaluating imatinib plus hydroxyurea in patients with progressive glioblastoma. | British journal of cancer 20091215 |
| Metronomic chemotherapy with daily, oral etoposide plus bevacizumab for recurrent malignant glioma: a phase II study. | British journal of cancer 20091215 |
| Phase I/II study of sequential therapy with irinotecan and S-1 for metastatic colorectal cancer. | British journal of cancer 20091215 |
| Improving outcome of chemotherapy of metastatic breast cancer by docosahexaenoic acid: a phase II trial. | British journal of cancer 20091215 |
| KRAS and BRAF mutations in advanced colorectal cancer are associated with poor prognosis but do not preclude benefit from oxaliplatin or irinotecan: results from the MRC FOCUS trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091210 |
| Phase II study of nimustine hydrochloride (ACNU) plus paclitaxel for refractory small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20091201 |
| Successful desensitization with cetuximab after an infusion reaction to panitumumab in patients with metastatic colorectal cancer. | Cancer chemotherapy and pharmacology 20091201 |
| Pharmacokinetic analysis of irinotecan plus bevacizumab in patients with advanced solid tumors. | Cancer chemotherapy and pharmacology 20091201 |
| Phase II trial of temozolomide (TMZ) plus irinotecan (CPT-11) in adults with newly diagnosed glioblastoma multiforme before radiotherapy. | Journal of neuro-oncology 20091201 |
| Phase II trial of preoperative irinotecan-cisplatin followed by concurrent irinotecan-cisplatin and radiotherapy for resectable locally advanced gastric and esophagogastric junction adenocarcinoma. | International journal of radiation oncology, biology, physics 20091201 |
| A randomized phase III study comparing adjuvant 5-fluorouracil/folinic acid with FOLFIRI in patients following complete resection of liver metastases from colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20091201 |
| Prolonged neutropenia after irinotecan-based chemotherapy in a child with polymorphisms of UGT1A1 and SLCO1B1. | Archives of disease in childhood 20091201 |
| Fourth complete remission with immunosuppression withdrawal and irinotecan after both autologous and allogeneic transplants for diffuse large B cell lymphoma. | Leukemia & lymphoma 20091201 |
| Irinotecan and temozolomide for Ewing sarcoma: the Memorial Sloan-Kettering experience. | Pediatric blood & cancer 20091201 |
| Irinotecan side effects relieved by the use of HI-6 oxime: in vivo experimental approach. | Basic & clinical pharmacology & toxicology 20091201 |
| In vivo antitumor efficacy of interleukin-21 in combination with chemotherapeutics. | Cytokine 20091201 |
| Integration of neoadjuvant and adjuvant chemotherapy in patients with resectable liver metastases from colorectal cancer. | Cancer treatment reviews 20091201 |
| Synergistic antiproliferative effect of mTOR inhibitors in combination with 5-fluorouracil in scirrhous gastric cancer. | Cancer science 20091201 |
| A phase II study of cisplatin and irinotecan as induction chemotherapy followed by accelerated hyperfractionated thoracic radiotherapy with daily low-dose carboplatin in unresectable stage III non-small cell lung cancer: JCOG 9510. | Japanese journal of clinical oncology 20091201 |
| Irinotecan plus capecitabine as a second-line treatment after failure of 5-fluorouracil and platinum in patients with advanced gastric cancer. | Japanese journal of clinical oncology 20091201 |
| Treatment of metastatic colorectal cancer in the elderly. | Current treatment options in oncology 20091201 |
| Herb-drug interactions with St John's wort (Hypericum perforatum): an update on clinical observations. | The AAPS journal 20091201 |
| Comeback for the camptothecins? | Leukemia & lymphoma 20091201 |
| Phase II trial of irinotecan, carboplatin, and bevacizumab in the treatment of patients with extensive-stage small-cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20091201 |
| The role of protein kinase C in the synergistic interaction of safingol and irinotecan in colon cancer cells. | International journal of oncology 20091201 |
| Implications of KRAS mutation status for the treatment of metastatic colorectal cancer. | Targeted oncology 20091201 |
| Clinical and economic value of screening for Kras mutations as predictors of response to epidermal growth factor receptor inhibitors. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20091201 |
| KRAS mutation in stage III colon cancer and clinical outcome following intergroup trial CALGB 89803. | Clinical cancer research : an official journal of the American Association for Cancer Research 20091201 |
| Brostallicin (PNU-166196), a new minor groove DNA binder: preclinical and clinical activity. | Expert opinion on investigational drugs 20091201 |
| [Efficacy of cetuximab combined with chemotherapy on advanced colorectal cancer: a report of 53 cases]. | Ai zheng = Aizheng = Chinese journal of cancer 20091201 |
| [Usefulness of clinical study of irinotecan and cisplatin for recurrent ovarian cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091201 |
| [A Case of gastric endocrine cell carcinoma successfully treated by FU plus irinotecan(CPT-11)adjuvant therapy against recurrent metastases]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091201 |
| [A case of interstitial pneumonitis induced by FOLFIRI+bevacizumab combination therapy for liver and lung metastasis of colon cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091201 |
| Generalizability of toxicity data from oncology clinical trials to clinical practice: toxicity of irinotecan-based regimens in patients with metastatic colorectal cancer. | Current oncology (Toronto, Ont.) 20091201 |
| [Chemotherapy for colorectal cancer]. | The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20091201 |
| [Use of anti-EGFR antibodies (cetuximab and panitumumab) in the treatment of metastatic colorectal cancer in KRAS wild type patients]. | Bulletin du cancer 20091201 |
| [Impact of mutational status of KRAS in the care of patients with colorectal cancer metastasis]. | Bulletin du cancer 20091201 |
| Phase I dose escalation study of gemcitabine plus irinotecan in advanced solid tumors. | Anticancer research 20091201 |
| Treatment of childhood sarcoma with irinotecan: bilirubin level as a predictor of gastrointestinal toxicity. | Journal of chemotherapy (Florence, Italy) 20091201 |
| Expression of HSP27, HSP72 and MRP proteins in in vitro co-culture of colon tumour cell spheroids with normal cells after incubation with rhTGF- beta1 and/or CPT-11. | Journal of biosciences 20091201 |
| Outcomes of irinotecan-based chemotherapy regimens in elderly Medicare patients with metastatic colorectal cancer. | The American journal of geriatric pharmacotherapy 20091201 |
| [Allicin enhances cytotoxicity of CPT-11 to colon cancer LoVo cell in vitro]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091201 |
| Drug exposure: still an excellent biomarker. | Biomarkers in medicine 20091201 |
| Current gene expression studies in esophageal carcinoma. | Current genomics 20091201 |
| 4-Pregnen-21-ol-3,20-dione-21-(4-bromobenzenesulfonate) (NSC 88915) and related novel steroid derivatives as tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors. | Journal of medicinal chemistry 20091126 |
| Randomized phase II study of gemcitabine administered at a fixed dose rate or in combination with cisplatin, docetaxel, or irinotecan in patients with metastatic pancreatic cancer: CALGB 89904. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091120 |
| Association of molecular markers with toxicity outcomes in a randomized trial of chemotherapy for advanced colorectal cancer: the FOCUS trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091120 |
| A randomised phase II study of modified FOLFIRI.3 vs modified FOLFOX as second-line therapy in patients with gemcitabine-refractory advanced pancreatic cancer. | British journal of cancer 20091117 |
| Expression of delta-like ligand 4 (Dll4) and markers of hypoxia in colon cancer. | British journal of cancer 20091117 |
| Humanised IgG1 antibody variants targeting membrane-bound carcinoembryonic antigen by antibody-dependent cellular cytotoxicity and phagocytosis. | British journal of cancer 20091117 |
| Bevacizumab for recurrent ependymoma. | Neurology 20091117 |
| Antiangiogenesis in recurrent glioblastoma: proof of principle. | Neurology international 20091116 |
| Current data and strategy in glioblastoma multiforme. | Journal of medicine and life 20091115 |
| XMT-1001, a novel polymeric camptothecin pro-drug in clinical development for patients with advanced cancer. | Advanced drug delivery reviews 20091112 |
| A phase-II trial of dose-dense chemotherapy in patients with disseminated thymoma: report of a Japan Clinical Oncology Group trial (JCOG 9605). | British journal of cancer 20091103 |
| Experimental study of combination therapy with S-1 against pancreatic cancer. | Cancer chemotherapy and pharmacology 20091101 |
| Safety and efficacy of first-line bevacizumab with FOLFOX, XELOX, FOLFIRI and fluoropyrimidines in metastatic colorectal cancer: the BEAT study. | Annals of oncology : official journal of the European Society for Medical Oncology 20091101 |
| Future directions in neoadjuvant therapy of rectal cancer: maximizing pathological complete response rates. | Cancer treatment reviews 20091101 |
| Treatment for colorectal liver metastases: a review. | Langenbeck's archives of surgery 20091101 |
| Prolonged low-dose administration of the cyclooxygenase-2 inhibitor celecoxib enhances the antitumor activity of irinotecan against neuroblastoma xenografts. | Cancer science 20091101 |
| Dofequidar fumarate sensitizes cancer stem-like side population cells to chemotherapeutic drugs by inhibiting ABCG2/BCRP-mediated drug export. | Cancer science 20091101 |
| 3-Methylindole is mutagenic and a possible pulmonary carcinogen. | Toxicological sciences : an official journal of the Society of Toxicology 20091101 |
| UGT1A1 genotyping: a predictor of irinotecan-associated side effects and drug efficacy? | Anti-cancer drugs 20091101 |
| Synthesis and antiproliferative evaluation of 6-arylindeno[1,2-c]quinoline derivatives. | Bioorganic & medicinal chemistry 20091101 |
| Combination of vandetanib, radiotherapy, and irinotecan in the LoVo human colorectal cancer xenograft model. | International journal of radiation oncology, biology, physics 20091101 |
| Fluorouracil versus combination of irinotecan plus cisplatin versus S-1 in metastatic gastric cancer: a randomised phase 3 study. | The Lancet. Oncology 20091101 |
| [Neoadjuvant therapy of adenocarcinomas of the upper gastrointestinal tract. Status of radiotherapy]. | Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 20091101 |
| Phase II trial of thalidomide, irinotecan and gemcitabine in chemonaive patients with advanced non-small cell lung cancer. | Cancer investigation 20091101 |
| Treatment of gastric cancer in Asia: the missing link. | The Lancet. Oncology 20091101 |
| Hepatic toxicities associated with the use of preoperative systemic therapy in patients with metastatic colorectal adenocarcinoma to the liver. | The oncologist 20091101 |
| [Intestinal absorption and secretion mechanism of carboxylate drugs]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20091101 |
| [Histological complete response in a case of advanced gastric endocrine carcinoma treated by irinotecan plus cisplatin]. | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20091101 |
| Cytotoxic effects of cardiac glycosides in colon cancer cells, alone and in combination with standard chemotherapeutic drugs. | Journal of natural products 20091101 |
| FDA drug approval summary: bevacizumab (Avastin) as treatment of recurrent glioblastoma multiforme. | The oncologist 20091101 |
| The importance of tumor volume in the prognosis of patients with glioblastoma: comparison of computerized volumetry and geometric models. | Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20091101 |
| Hypoxia-induced downregulation of autophagy mediator Beclin 1 reduces the susceptibility of malignant intestinal epithelial cells to hypoxia-dependent apoptosis. | Autophagy 20091101 |
| [Combination chemotherapy of S-1 and CPT-11 for advanced recurrent gastric cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091101 |
| [Chemotherapy-induced myelosuppression and treatment efficacy in extensive-stage small cell lung cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091101 |
| [A case of advanced gastric cancer that a medical therapy effect was provided grade 3 by a histopathological diagnosis after long-term chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091101 |
| [A successful two-stage treatment with CDDP and CPT-11 for pancreatic neuroendocrine carcinoma with liver metastasis]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091101 |
| [Huge ascending colon carcinoma, treated successfully with S-1 plus CPT-11, followed by significant tumor reduction and curative resection--a case report]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091101 |
| [A case of advanced rectal cancer that responded to S-1 with an extended complete response]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091101 |
| [Predictive factors for histopathological liver injury in the patients who received preoperative systemic chemotherapy for colorectal liver metastases]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091101 |
| [A case of rectal cancer with lung metastases responding to cetuximab]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091101 |
| [A case of liver metastasis treated by cetuximab monotherapy with partial response]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091101 |
| [A case report of metastatic liver tumor from rectosigmoid colon cancer demonstrating a pathological complete response with FOLFOX and FOLFIRI treatment]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091101 |
| [Intermittent hepatic arterial infusion with systemic chemotherapy for metastatic colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091101 |
| [A case report of multiple liver metastases from colorectal cancer effectively treated with systemic chemotherapy and hepatic arterial infusion]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091101 |
| [A curative resection with the combination of portal vein branch embolization and systemic chemotherapy in a patient with synchronous multiple and bilobar colorectal liver metastases]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091101 |
| [A case of advanced right colonic cancer successfully treated by surgery and post operative chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091101 |
| [Treatment for intrapelvic recurrence of rectal cancer--resection versus chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091101 |
| [A long term survivor of advanced gastric cancer treated with multi-drug combination chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091101 |
| [A case of long-term survival of unresectable-advanced gastric cancer due to chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091101 |
| [A case of bilateral pulmonary metastasis from gastric cancer performed radical thoracoscopic lobectomy after neoadjuvant chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091101 |
| Overview of systemic therapy for colorectal cancer. | Clinics in colon and rectal surgery 20091101 |
| Heterogeneity of adenosine triphosphate-based chemotherapy response assay in colorectal cancer--secondary publication. | Yonsei medical journal 20091031 |
| UGT1A1 gene polymorphism: impact on toxicity and efficacy of irinotecan-based regimens in metastatic colorectal cancer. | World journal of gastroenterology 20091028 |
| Amphiregulin and epiregulin mRNA expression in primary tumors predicts outcome in metastatic colorectal cancer treated with cetuximab. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091020 |
| Phase I and pharmacokinetic study of cetuximab and irinotecan in children with refractory solid tumors: a study of the pediatric oncology experimental therapeutic investigators' consortium. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091020 |
| Phase II study of cetuximab in combination with cisplatin and docetaxel in patients with untreated advanced gastric or gastro-oesophageal junction adenocarcinoma (DOCETUX study). | British journal of cancer 20091020 |
| Bevacizumab in association with de Gramont 5-fluorouracil/folinic acid in patients with oxaliplatin-, irinotecan-, and cetuximab-refractory colorectal cancer: a single-center phase 2 trial. | Cancer 20091015 |
| Patterns of relapse and prognosis after bevacizumab failure in recurrent glioblastoma. | Neurology 20091013 |
| Proteasome-dependent processing of topoisomerase I-DNA adducts into DNA double strand breaks at arrested replication forks. | The Journal of biological chemistry 20091009 |
| Biomarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer. | Journal of the National Cancer Institute 20091007 |
| Capecitabine in combination with irinotecan (XELIRI), administered as a 2-weekly schedule, as first-line chemotherapy for patients with metastatic colorectal cancer: a phase II study of the Spanish GOTI group. | British journal of cancer 20091006 |
| Surgery with curative-intent in patients treated with first-line chemotherapy plus bevacizumab for metastatic colorectal cancer First BEAT and the randomised phase-III NO16966 trial. | British journal of cancer 20091006 |
| The management of colorectal liver metastases: Expanding the role of hepatic resection in the age of multimodal therapy. | Critical reviews in oncology/hematology 20091001 |
| Oxaliplatin, irinotecan, and fluorouracil/folinic acid in advanced gastric cancer: a multicenter phase II trial of the Southern Italy Cooperative Oncology Group. | Cancer chemotherapy and pharmacology 20091001 |
| Irinotecan and oxaliplatin combination as the first-line treatment for patients with advanced non-small cell lung cancer. | Cancer chemotherapy and pharmacology 20091001 |
| Perturbation of DNA repair pathways by proteasome inhibitors corresponds to enhanced chemosensitivity of cells to DNA damage-inducing agents. | Cancer chemotherapy and pharmacology 20091001 |
| Role of a second chemotherapy in recurrent malignant glioma patients who progress on bevacizumab. | Neuro-oncology 20091001 |
| Antitumor activity of the HER2 dimerization inhibitor pertuzumab on human colon cancer cells in vitro and in vivo. | Journal of cancer research and clinical oncology 20091001 |
| Paclitaxel combined with siRNA targeting HPV16 oncogenes improves cytotoxicity for cervical carcinoma. | Cancer gene therapy 20091001 |
| Cytoprotective activity of amifostine on cultured human lymphocytes exposed to irinotecan. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20091001 |
| Docetaxel and irinotecan in recurrent or metastatic head and neck cancer: a phase 2 trial of the Eastern Cooperative Oncology Group. | Cancer 20091001 |
| Quantitation of Irinotecan and its two major metabolites using a liquid chromatography-electrospray ionization tandem mass spectrometric. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091001 |
| Metronomic 5-fluorouracil, oxaliplatin and irinotecan in colorectal cancer. | European journal of pharmacology 20091001 |
| Single nucleotide polymorphism in ABCG2 is associated with irinotecan-induced severe myelosuppression. | Journal of human genetics 20091001 |
| Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091001 |
| Long-term outcome of unresectable metastatic colorectal cancer: does 'adjuvant' chemotherapy play a role after resection? | Annals of surgery 20091001 |
| [Hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC): evaluation, prevention and policies to avoid occupational exposure for operating room personnel]. | Bulletin du cancer 20091001 |
| Irinotecan-induced mucositis manifesting as diarrhoea corresponds with an amended intestinal flora and mucin profile. | International journal of experimental pathology 20091001 |
| Chemotherapy: Optimizing irinotecan regimens for colorectal cancer. | Nature reviews. Clinical oncology 20091001 |
| Chemotherapy: Irinotecan or etoposide as front-line therapy for SCLC? | Nature reviews. Clinical oncology 20091001 |
| CEACAM5-targeted therapy of human colonic and pancreatic cancer xenografts with potent labetuzumab-SN-38 immunoconjugates. | Clinical cancer research : an official journal of the American Association for Cancer Research 20091001 |
| Adenocarcinoma of the small bowel: a surgical dilemma. | Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20091001 |
| [Progress in chemotherapy for advanced gastric cancer]. | Ai zheng = Aizheng = Chinese journal of cancer 20091001 |
| Improved patient and regimen selection in locally advanced rectal cancer: who, how, and what next? | Clinical colorectal cancer 20091001 |
| [Treatment strategy for neuroendocrine carcinoma of the lung]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091001 |
| [A case of recurrent rectal cancer with multiple lung metastases successfully treated with S-1 and CPT-11 combination chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091001 |
| [A case of gastric cancer with peritoneal dissemination who achieved long survival by successive treatments with S-1 in combination with CDDP, paclitaxel and irinotecan]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091001 |
| [A case of recurrent gastric cancer during adjuvant chemotherapy with S-1, treated by S-1 combination chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091001 |
| [A case of liver metastasis of rectal cancer, refractory to previous chemotherapy(5-FU/LV, irinotecan, oxaliplatin) responding to bevacizumab combined with FOLFIRI chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20091001 |
| Combined chemotherapy with carboplatin plus irinotecan showed favorable efficacy in a patient with relapsed small cell carcinoma of the prostate complicated with meningeal carcinomatosis. | International journal of clinical oncology 20091001 |
| Advanced hepatocellular carcinoma treated effectively with irinotecan via hepatic arterial infusion followed by proton beam therapy. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20091001 |
| [Adjuvant chemotherapy after radical liver resection in the treatment of metastases from colorectal carcinoma]. | Minerva chirurgica 20091001 |
| Small cell carcinoma of the breast. | Journal of the National Medical Association 20091001 |
| The overexpression of ERCC-1 is involved in the resistance of lung cancer cells to cetuximab combined with DDP. | Cancer biology & therapy 20091001 |
| [Combination with SN-38 on human colon cancer LoVo cells]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20091001 |
| Tyrosine kinase inhibitor enhances the bioavailability of oral irinotecan in pediatric patients with refractory solid tumors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090920 |
| Molecular markers of response and toxicity to FOLFOX chemotherapy in metastatic colorectal cancer. | British journal of cancer 20090915 |
| Preoperative downstaging chemoradiation with concurrent irinotecan and capecitabine in MRI-defined locally advanced rectal cancer: a phase I trial (NWCOG-2). | British journal of cancer 20090915 |
| Induction of thrombospondin-1 partially mediates the anti-angiogenic activity of dexrazoxane. | British journal of cancer 20090915 |
| Sirolimus, bevacizumab, 5-Fluorouracil and irinotecan for advanced colorectal cancer: a pilot study. | World journal of gastroenterology 20090914 |
| International guidelines for management of metastatic breast cancer: combination vs sequential single-agent chemotherapy. | Journal of the National Cancer Institute 20090902 |
| Fotemustine as second-line treatment for recurrent or progressive glioblastoma after concomitant and/or adjuvant temozolomide: a phase II trial of Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO). | Cancer chemotherapy and pharmacology 20090901 |
| Simvastatin plus irinotecan, 5-fluorouracil, and leucovorin (FOLFIRI) as first-line chemotherapy in metastatic colorectal patients: a multicenter phase II study. | Cancer chemotherapy and pharmacology 20090901 |
| In vitro chemosensitivity based on depth of invasion in advanced colorectal cancer using ATP-based chemotherapy response assay (ATP-CRA). | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20090901 |
| Age- and sex-related expression and activity of carboxylesterase 1 and 2 in mouse and human liver. | Drug metabolism and disposition: the biological fate of chemicals 20090901 |
| Radiofrequency ablation of colorectal liver metastases downstaged by chemotherapy. | Acta radiologica (Stockholm, Sweden : 1987) 20090901 |
| Synchronous colorectal liver metastases: is it time to reconsider traditional paradigms of management? | Annals of surgical oncology 20090901 |
| Cost effectiveness of pharmacogenetic testing for uridine diphosphate glucuronosyltransferase 1A1 before irinotecan administration for metastatic colorectal cancer. | Cancer 20090901 |
| A feasibility study of UFT/LV and irinotecan (TEGAFIRI) in advanced or metastatic colorectal cancer: Osaka Gastrointestinal Cancer Chemotherapy Study Group (OGSG) PROG 0304. | Japanese journal of clinical oncology 20090901 |
| Chemotherapy-associated hepatotoxicity: do we need to be concerned? | Annals of surgical oncology 20090901 |
| The role of transporters in the pharmacokinetics of orally administered drugs. | Pharmaceutical research 20090901 |
| Quality of life of palliative chemotherapy naive patients with advanced adenocarcinoma of the stomach or esophagogastric junction treated with irinotecan combined with 5-fluorouracil and folinic acid: results of a randomised phase III trial. | Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 20090901 |
| Efficacy of 5-FU/LV plus CPT-11 as first-line adjuvant chemotherapy for stage IIIa colorectal cancer. | Oncology reports 20090901 |
| Current perspective: bevacizumab in colorectal cancer--a time for reappraisal? | European journal of cancer (Oxford, England : 1990) 20090901 |
| Pharmacogenetics of solid tumors: directed therapy in breast, lung, and colorectal cancer: a paper from the 2008 william beaumont hospital symposium on molecular pathology. | The Journal of molecular diagnostics : JMD 20090901 |
| Phase II study of neoadjuvant chemotherapy and extended surgery for locally advanced gastric cancer. | The British journal of surgery 20090901 |
| Radioembolization of liver metastases in patients with colorectal cancer: a nonsurgical treatment with combined modality potential. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090901 |
| Treatment of fluorouracil-refractory patients with liver metastases from colorectal cancer by using yttrium-90 resin microspheres plus concomitant systemic irinotecan chemotherapy. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090901 |
| Is there a palliative benefit of gemcitabine plus fluoropyrimidines in patients with refractory colorectal cancer? A review of the literature previously presented: poster at the 2008 Gastrointestinal Cancer Symposium (Abstract No. 512). | Expert opinion on investigational drugs 20090901 |
| Tissue biomarker development in a multicentre trial context: a feasibility study on the PETACC3 stage II and III colon cancer adjuvant treatment trial. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090901 |
| Colorectal cancer: Irinotecan therapy-following a trail of breadcrumbs? | Nature reviews. Gastroenterology & hepatology 20090901 |
| Is there a role for second-line chemotherapy in advanced gastric cancer? | The Lancet. Oncology 20090901 |
| [Efficacy of FORFIRI regimen on oxaliplatin-based chemotherapy-failed advanced colorectal cancer]. | Ai zheng = Aizheng = Chinese journal of cancer 20090901 |
| [Correlation of chemosensitivity tested using histoculture drug response assay to expression of multidrug resistance genes and proteins in colorectal cancer tissues]. | Ai zheng = Aizheng = Chinese journal of cancer 20090901 |
| [Clinical significance of a transient increase in carcinoembryonic antigen and carbohydrate antigen 19-9 in patients with metastatic colorectal cancer receiving chemotherapy]. | Ai zheng = Aizheng = Chinese journal of cancer 20090901 |
| Serum vitamin B12 and folate status among patients with chemotherapy treatment for advanced colorectal cancer. | Upsala journal of medical sciences 20090901 |
| Association between Genetic Polymorphism of Multidrug Resistance 1 Gene and Sasang Constitutions. | Evidence-based complementary and alternative medicine : eCAM 20090901 |
| [Clinical effects of Hange-shashin-to on combination therapy of S-1/irinotecan against the for patients with metastatic gastric and colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090901 |
| [Assessment of total bilirubin or SN-38/SN-38G ratio as a predictor of severe irinotecan toxicity]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090901 |
| [A case of superficial small cell carcinoma of the esophagus]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090901 |
| Chemotherapy, which drugs and when. | European journal of cancer (Oxford, England : 1990) 20090901 |
| [The development of the first line treatment of metastatic colorectal cancer (mCRC)]. | Magyar onkologia 20090901 |
| Concentration of vascular endothelial growth factor after intracameral bevacizumab injection in eyes with neovascular glaucoma. | Korean journal of ophthalmology : KJO 20090901 |
| The BC Cancer Agency Compassionate Access Program: outcome analysis of patients with esophagogastric cancer. | Current oncology (Toronto, Ont.) 20090901 |
| Efficacy of third-line therapy using bevacizumab in a patient with metastatic colorectal cancer. | Current oncology (Toronto, Ont.) 20090901 |
| Histone deacetylase inhibitors valproate and trichostatin A are toxic to neuroblastoma cells and modulate cytochrome P450 1A1, 1B1 and 3A4 expression in these cells. | Interdisciplinary toxicology 20090901 |
| Medical treatment of advanced colorectal cancer in 2009. | Therapeutic advances in medical oncology 20090901 |
| Secondary hepatic resection as a therapeutic goal in advanced colorectal cancer. | World journal of gastroenterology 20090821 |
| Gene Polymorphisms and Chemotherapy in Non-small Cell Lung Cancer. | Zhongguo fei ai za zhi = Chinese journal of lung cancer 20090820 |
| KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer. | British journal of cancer 20090818 |
| Gemcitabine alone or in combination with cisplatin in patients with advanced or metastatic cholangiocarcinomas or other biliary tract tumours: a multicentre randomised phase II study - The UK ABC-01 Study. | British journal of cancer 20090818 |
| Triterpenes augment the inhibitory effects of anticancer drugs on growth of human esophageal carcinoma cells in vitro and suppress experimental metastasis in vivo. | International journal of cancer 20090815 |
| Irinotecan therapy and molecular targets in colorectal cancer: a systemic review. | World journal of gastroenterology 20090807 |
| DLL4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency. | Cell stem cell 20090807 |
| Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer. | British journal of cancer 20090804 |
| Phase I trial of weekly cisplatin, irinotecan and paclitaxel in patients with advanced gastrointestinal cancer. | Investigational new drugs 20090801 |
| A multicenter randomized phase II study of the irinotecan/gemcitabine doublet versus irinotecan monotherapy in previously treated patients with extensive stage small-cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20090801 |
| A phase II trial evaluating capecitabine and irinotecan as second line treatment in patients with oesophago-gastric cancer who have progressed on, or within 3 months of platinum-based chemotherapy. | Cancer chemotherapy and pharmacology 20090801 |
| Cetuximab in combination with capecitabine, irinotecan, and radiotherapy for patients with locally advanced rectal cancer: results of a Phase II MARGIT trial. | International journal of radiation oncology, biology, physics 20090801 |
| Gastric cancer. | Critical reviews in oncology/hematology 20090801 |
| Single and combined supplementation of glutamine and n-3 polyunsaturated fatty acids on host tolerance and tumour response to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothecin (CPT-11)/5-fluorouracil chemotherapy in rats bearing Ward colon tumour. | The British journal of nutrition 20090801 |
| Global variation in CYP2C8-CYP2C9 functional haplotypes. | The pharmacogenomics journal 20090801 |
| Prolonged survival in a patient with BRCA2 associated metastatic pancreatic cancer after exposure to camptothecin: a case report and review of literature. | Anti-cancer drugs 20090801 |
| Radiological tumor size decrease at week 6 is a potent predictor of outcome in chemorefractory metastatic colorectal cancer treated with cetuximab (BOND trial). | Annals of oncology : official journal of the European Society for Medical Oncology 20090801 |
| Concomitant exposure of ovarian cancer cells to docetaxel, CPT-11 or SN-38 and adenovirus-mediated p53 gene therapy. | Anti-cancer drugs 20090801 |
| The case for selective use of pre-operative chemotherapy for hepatic colorectal metastases: more is not always better. | Annals of surgical oncology 20090801 |
| Differential effects of EGFR ligands on endocytic sorting of the receptor. | Traffic (Copenhagen, Denmark) 20090801 |
| Cigarettes smoking habit may reduce benefit from cetuximab-based treatment in advanced colorectal cancer patients. | Expert opinion on biological therapy 20090801 |
| 7-Cycloalkylcamptothecin derivatives: Preparation and biological evaluation. | Bioorganic & medicinal chemistry letters 20090801 |
| Differentiation-related gene-1 decreases Bim stability by proteasome-mediated degradation. | Cancer research 20090801 |
| Irinotecan use during pregnancy. | Obstetrics and gynecology 20090801 |
| Adjuvant chemotherapy for stages II, III and IV of colon cancer. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20090801 |
| Chemoresponsiveness associated with canonical molecular changes in colorectal adenocarcinomas. | Anticancer research 20090801 |
| A novel K-ras mutation in colorectal cancer. A case report and literature review. | Anticancer research 20090801 |
| Drug ratio-dependent antitumor activity of irinotecan and cisplatin combinations in vitro and in vivo. | Molecular cancer therapeutics 20090801 |
| [Chemotherapy and hepatectomy for liver metastasis from colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090801 |
| [Combination of irinotecan and Mitomycin C as second-line chemotherapy for patients with unresectable advanced or recurrent gastric cancer in clinical practice]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090801 |
| [Report of a case successfully treated with chemo-radiation against local recurrence after gastric cancer surgery]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090801 |
| [A case of advanced colon cancer treated with preoperative chemotherapy (IRIS) leading to clinical complete response]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090801 |
| [Effectiveness of S-1 plus CPT-11 therapy for an elderly patient with recurrent colon cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090801 |
| Developmental tumourigenesis: NCAM as a putative marker for the malignant renal stem/progenitor cell population. | Journal of cellular and molecular medicine 20090801 |
| Desmoplastic small round cell tumor: impact of F-FDG PET induced treatment strategy in a patient with long-term outcome. | Rare tumors 20090722 |
| Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array. | British journal of cancer 20090721 |
| Do we need biopsies of metastases for colorectal cancer patients? | British journal of cancer 20090721 |
| Conversion to resectability using hepatic artery infusion plus systemic chemotherapy for the treatment of unresectable liver metastases from colorectal carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090720 |
| [Predictive biomarkers in colorectal cancer]. | Revue medicale suisse 20090715 |
| Outcome of primary tumor in patients with synchronous stage IV colorectal cancer receiving combination chemotherapy without surgery as initial treatment. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090710 |
| Cost-effectiveness analysis of XELOX for metastatic colorectal cancer based on the NO16966 and NO16967 trials. | British journal of cancer 20090707 |
| High Ki67, Bax, and thymidylate synthase expression well correlates with response to chemoradiation therapy in locally advanced rectal cancers: proposal of a logistic model for prediction. | British journal of cancer 20090707 |
| Any progress in the management of advanced pancreatic cancer? Highlights from the 45th ASCO annual meeting. Orlando, FL, USA. May 29-June 2, 2009. | JOP : Journal of the pancreas 20090706 |
| The role of salvage treatment in advanced colorectal cancer. | Critical reviews in oncology/hematology 20090701 |
| Simplified FOLFIRI in pre-treated patients with metastatic gastric cancer. | Cancer chemotherapy and pharmacology 20090701 |
| Topoisomerase I and IIalpha protein expression in primary colorectal cancer and recurrences following 5-fluorouracil-based adjuvant chemotherapy. | Cancer chemotherapy and pharmacology 20090701 |
| Application of prolonged microdialysis sampling in carboplatin-treated cancer patients. | Cancer chemotherapy and pharmacology 20090701 |
| Toxicity of daily low dose cisplatin in radiochemotherapy for locally advanced head and neck cancer. | Journal of cancer research and clinical oncology 20090701 |
| Bevacizumab and irinotecan treatment for progressive diffuse brainstem glioma: case report. | Journal of neuro-oncology 20090701 |
| Can cetuximab affect paraneoplastic myopathy? | Journal of neuro-oncology 20090701 |
| Objective response of multiply recurrent low-grade gliomas to bevacizumab and irinotecan. | Pediatric blood & cancer 20090701 |
| Safety and feasibility of switching from phenytoin to levetiracetam monotherapy for glioma-related seizure control following craniotomy: a randomized phase II pilot study. | Journal of neuro-oncology 20090701 |
| Neutropaenia as a prognostic factor in metastatic colorectal cancer patients undergoing chemotherapy with first-line FOLFOX. | European journal of cancer (Oxford, England : 1990) 20090701 |
| Prognostic significance of circulating tumor cells in patients with metastatic colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20090701 |
| A phase I/II trial of fixed-dose docetaxel plus irinotecan and escalating doses of estramustine phosphate for second-line or greater treatment of selected advanced solid tumors. | Anti-cancer drugs 20090701 |
| Regulation of tissue-specific carboxylesterase expression by pregnane x receptor and constitutive androstane receptor. | Drug metabolism and disposition: the biological fate of chemicals 20090701 |
| Intracellular dynamics of topoisomerase I inhibitor, CPT-11, by slit-scanning confocal Raman microscopy. | Histochemistry and cell biology 20090701 |
| Dual chemotherapy and photodynamic therapy in an HT-29 human colon cancer xenograft model using SN-38-loaded chlorin-core star block copolymer micelles. | Biomaterials 20090701 |
| Phase 1 trial of temozolomide plus irinotecan plus O6-benzylguanine in adults with recurrent malignant glioma. | Cancer 20090701 |
| Phase II trial of docetaxel-irinotecan combination in advanced esophageal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20090701 |
| Topoisomerase I expression correlates to response to neoadjuvant irinotecan-based chemoradiation in rectal cancer. | Anti-cancer drugs 20090701 |
| Oxaliplatin or irinotecan as adjuvant therapy for colon cancer: the results are in. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090701 |
| Randomized phase III trial comparing biweekly infusional fluorouracil/leucovorin alone or with irinotecan in the adjuvant treatment of stage III colon cancer: PETACC-3. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090701 |
| Predictive and prognostic markers for the outcome of chemotherapy in advanced colorectal cancer, a retrospective analysis of the phase III randomised CAIRO study. | European journal of cancer (Oxford, England : 1990) 20090701 |
| A review on the use of molecular markers of cytotoxic therapy for colorectal cancer, what have we learned? | European journal of cancer (Oxford, England : 1990) 20090701 |
| Antitumor activity of NK012 combined with cisplatin against small cell lung cancer and intestinal mucosal changes in tumor-bearing mouse after treatment. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090701 |
| Establishment and biological analysis of the EC109/CDDP multidrug-resistant esophageal squamous cell carcinoma cell line. | Oncology reports 20090701 |
| Comprehensive analysis of excision repair complementation group 1, glutathione S-transferase, thymidylate synthase and uridine diphosphate glucuronosyl transferase 1A1 polymorphisms predictive for treatment outcome in patients with advanced gastric cancer treated with FOLFOX or FOLFIRI. | Oncology reports 20090701 |
| Treatment of spinal cord tumors. | Current treatment options in neurology 20090701 |
| Epigenetic mechanisms of irinotecan sensitivity in colorectal cancer cell lines. | Molecular cancer therapeutics 20090701 |
| Genetic prognostic and predictive markers in colorectal cancer. | Nature reviews. Cancer 20090701 |
| Preclinical results of camptothecin-polymer conjugate (IT-101) in multiple human lymphoma xenograft models. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090701 |
| Acquired Fanconi syndrome after treatment with capecitabine, irinotecan, and bevacizumab. | The Annals of pharmacotherapy 20090701 |
| [Clinical research of bevacizumab in combination with irinotecan, fluorouracil and leucovorin for advanced metastatic colorectal cancer]. | Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20090701 |
| Pharmacodynamic genes do not influence risk of neutropenia in cancer patients treated with moderately high-dose irinotecan. | Pharmacogenomics 20090701 |
| Individual differences in rate-limiting reactions during metabolism of irinotecan hydrochloride. | Gan to kagaku ryoho. Cancer & chemotherapy 20090701 |
| [Two cases of advanced colorectal cancer with UGT1A1*28 homozygosity treated by FOLFIRI]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090701 |
| [A case of hyperammonemia with encephalopathy related to FOLFIRI chemotherapy for advanced colon cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090701 |
| Inhibition of colon cancer growth by methylselenocysteine-induced angiogenic chemomodulation is influenced by histologic characteristics of the tumor. | Clinical colorectal cancer 20090701 |
| S-1: a new oral fluoropyrimidine in the treatment of patients with advanced non-small-cell lung cancer. | Clinical lung cancer 20090701 |
| Impact of irinotecan and oxaliplatin on overall survival in patients with metastatic colorectal cancer: a population-based study. | Journal of oncology practice 20090701 |
| New approaches for cancer treatment: antitumor drugs based on gene-targeted nucleic acids. | Acta naturae 20090701 |
| TRAP1, a novel mitochondrial chaperone responsible for multi-drug resistance and protection from apoptotis in human colorectal carcinoma cells. | Cancer letters 20090628 |
| Improved, selective, human intestinal carboxylesterase inhibitors designed to modulate 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (Irinotecan; CPT-11) toxicity. | Journal of medicinal chemistry 20090625 |
| Tie2-mediated multidrug resistance in malignant gliomas is associated with upregulation of ABC transporters. | Oncogene 20090618 |
| Bevacizumab combined with gemcitabine and capecitabine for advanced pancreatic cancer: a phase II study. | British journal of cancer 20090616 |
| Comparing safety and efficacy of first-line irinotecan/fluoropyrimidine combinations in elderly versus nonelderly patients with metastatic colorectal cancer: findings from the bolus, infusional, or capecitabine with camptostar-celecoxib study. | Cancer 20090615 |
| Phase III noninferiority trial comparing irinotecan with oxaliplatin, fluorouracil, and leucovorin in patients with advanced colorectal carcinoma previously treated with fluorouracil: N9841. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090610 |
| Molecular changes to HeLa cells on continuous exposure to SN-38, an active metabolite of irinotecan hydrochloride. | Cancer letters 20090608 |
| Antiangiogenic therapy with bevacizumab in recurrent malignant gliomas: analysis of the response and core pathway aberrations. | Chinese medical journal 20090605 |
| FDG uptake is a surrogate marker for defining the optimal biological dose of the mTOR inhibitor everolimus in vivo. | British journal of cancer 20090602 |
| A multicenter phase II study of the combination of oxaliplatin, irinotecan and capecitabine in the first-line treatment of metastatic colorectal cancer. | British journal of cancer 20090602 |
| Treatment in advanced colorectal cancer: what, when and how? | British journal of cancer 20090602 |
| A phase II study of S-1 plus irinotecan and oxaliplatin in heavily-treated patients with metastatic colorectal cancer. | Investigational new drugs 20090601 |
| Phase I trial of neoadjuvant chemoradiotherapy (CRT) with capecitabine and weekly irinotecan followed by laparoscopic total mesorectal excision (LTME) in rectal cancer patients. | Investigational new drugs 20090601 |
| Dose finding study of erlotinib combined to capecitabine and irinotecan in pretreated advanced colorectal cancer patients. | Cancer chemotherapy and pharmacology 20090601 |
| Irinotecan-induced mucositis is associated with changes in intestinal mucins. | Cancer chemotherapy and pharmacology 20090601 |
| DNA copy number profiles of primary tumors as predictors of response to chemotherapy in advanced colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20090601 |
| Efficacy of FOLFIRI-3 (irinotecan D1,D3 combined with LV5-FU) or other irinotecan-based regimens in oxaliplatin-pretreated metastatic colorectal cancer in the GERCOR OPTIMOX1 study. | Annals of oncology : official journal of the European Society for Medical Oncology 20090601 |
| Early prediction of response to first-line chemotherapy by sequential [18F]-2-fluoro-2-deoxy-D-glucose positron emission tomography in patients with advanced colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20090601 |
| Doxorubicin and mitoxantrone drug eluting beads for the treatment of experimental peritoneal carcinomatosis in colorectal cancer. | International journal of cancer 20090601 |
| Potent antitumor effect of SN-38-incorporating polymeric micelle, NK012, against malignant glioma. | International journal of cancer 20090601 |
| Irinotecan as palliative chemotherapy for metastatic colorectal cancer: evolving tactics following initial treatment. | International journal of colorectal disease 20090601 |
| Disposition of flavonoids via enteric recycling: UDP-glucuronosyltransferase (UGT) 1As deficiency in Gunn rats is compensated by increases in UGT2Bs activities. | The Journal of pharmacology and experimental therapeutics 20090601 |
| Topoisomerase I involvement in schedule-dependent interaction between 5-fluoro-uracil and irinotecan in the treatment of colorectal cancer. | Cancer chemotherapy and pharmacology 20090601 |
| A landmark point analysis with cytotoxic agents for advanced NSCLC. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20090601 |
| Current place of high-dose irinotecan chemotherapy in patients with metastatic colorectal cancer. | Journal of cancer research and clinical oncology 20090601 |
| Irinogenetics: how many stars are there in the sky? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090601 |
| Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090601 |
| PTEN expression and KRAS mutations on primary tumors and metastases in the prediction of benefit from cetuximab plus irinotecan for patients with metastatic colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090601 |
| Effects of oral administration of S-1 on the pharmacokinetics of SN-38, irinotecan active metabolite, in patients with advanced colorectal cancer. | Therapeutic drug monitoring 20090601 |
| A novel sulindac derivative that does not inhibit cyclooxygenases but potently inhibits colon tumor cell growth and induces apoptosis with antitumor activity. | Cancer prevention research (Philadelphia, Pa.) 20090601 |
| Histological patterns in drug-induced liver disease. | Journal of clinical pathology 20090601 |
| [Pharmacogenomics]. | Nihon rinsho. Japanese journal of clinical medicine 20090601 |
| Gene therapy targeting nuclear factor-kappaB: towards clinical application in inflammatory diseases and cancer. | Current gene therapy 20090601 |
| Molecular mechanisms of sequence-dependent antitumor effects of SN-38 and 5-fluorouracil combination therapy against colon cancer cells. | Anticancer research 20090601 |
| [A case of marked response to CPT-11+CDDP neoadjuvant chemotherapy for advanced gastric cancer with paraaortic lymph node metastasis enabling curative resection and over 10-year survival]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090601 |
| [Two cases of KRAS wild-type unresectable or recurrent colorectal cancer effectively treated by cetuximab after progression of prior chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090601 |
| Preparation of pegylated nano-liposomal formulation containing SN-38: In vitro characterization and in vivo biodistribution in mice. | Acta pharmaceutica (Zagreb, Croatia) 20090601 |
| [Chemotherapy of elderly patients with colorectal cancer]. | Magyar onkologia 20090601 |
| Epidermal growth factor receptor expression discrepancies in metastatic colorectal cancer patients treated with cetuximab plus irinotecan-based chemotherapy refractory to irinotecan and oxaliplatin. | Diseases of the colon and rectum 20090601 |
| Upregulation of glycolytic enzymes in proteins secreted from human colon cancer cells with 5-fluorouracil resistance. | Electrophoresis 20090601 |
| Integration of irinotecan and cisplatin with early concurrent conventional radiotherapy for limited-disease SCLC (LD-SCLC). | International journal of clinical oncology 20090601 |
| Evolving approaches to metastatic breast cancer previously treated with anthracyclines and taxanes. | Clinical breast cancer 20090601 |
| [Efficacy and safety of combination of irinotecan and capecitabine in patients with metastatic colorectal cancer after failure of chemotherapy with oxaliplatin]. | Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20090601 |
| [Chemotherapy and biological treatment in the complex management of large intestinal and rectal carcinomas. When, why, how?]. | Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti 20090601 |
| Molecular markers of tumor progression in melanoma. | Current genomics 20090601 |
| [Efficacy of cetuximab in therapy of metastatic colorectal cancer: a system evaluation]. | Zhonghua yi xue za zhi 20090526 |
| Novel irinotecan-loaded liposome using phytic acid with high therapeutic efficacy for colon tumors. | Journal of controlled release : official journal of the Controlled Release Society 20090521 |
| Phase III trial of irinotecan/cisplatin compared with etoposide/cisplatin in extensive-stage small-cell lung cancer: clinical and pharmacogenomic results from SWOG S0124. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090520 |
| UGT1A and irinotecan toxicity: keeping it in the family. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090520 |
| Predictive role of the UGT1A1, UGT1A7, and UGT1A9 genetic variants and their haplotypes on the outcome of metastatic colorectal cancer patients treated with fluorouracil, leucovorin, and irinotecan. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090520 |
| Prophylactic ciprofloxacin treatment prevented high mortality, and modified systemic and intestinal immune function in tumour-bearing rats receiving dose-intensive CPT-11 chemotherapy. | British journal of cancer 20090519 |
| Synthesis and biological activities of a pH-dependently activated water-soluble prodrug of a novel hexacyclic camptothecin analog. | Bioorganic & medicinal chemistry letters 20090515 |
| Phase I study of bortezomib and cetuximab in patients with solid tumours expressing epidermal growth factor receptor. | British journal of cancer 20090505 |
| Bevacizumab and irinotecan for recurrent oligodendroglial tumors. | Neurology 20090505 |
| Phase I and pharmacokinetic study of mitomycin C and celecoxib as potential modulators of tumor resistance to irinotecan in patients with solid malignancies. | Cancer chemotherapy and pharmacology 20090501 |
| Irinotecan monotherapy as second-line treatment in advanced pancreatic cancer. | Cancer chemotherapy and pharmacology 20090501 |
| Formulation and comparative characterization of chitosan, gelatin, and chitosan-gelatin-coated liposomes of CPT-11-HCl. | Drug development and industrial pharmacy 20090501 |
| Life-threatening toxicities in a patient with UGT1A1*6/*28 and SLCO1B1*15/*15 genotypes after irinotecan-based chemotherapy. | Cancer chemotherapy and pharmacology 20090501 |
| The importance of KRAS mutations and EGF61A>G polymorphism to the effect of cetuximab and irinotecan in metastatic colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20090501 |
| Phase I study of weekly cisplatin, bolus fluorouracil and escalating doses of irinotecan in advanced solid tumors. | Cancer investigation 20090501 |
| Recent progress in pathogenesis and management of colorectal cancer. Eighteenth International Symposium of the Hiroshima Cancer Seminar, November 2008. | Cancer science 20090501 |
| Different inhibitory effects in rat and human carboxylesterases. | Drug metabolism and disposition: the biological fate of chemicals 20090501 |
| Is there a survival benefit to neoadjuvant versus adjuvant chemotherapy, combined with surgery for resectable colorectal liver metastases? | World journal of surgery 20090501 |
| A phase 2 clinical trial of panitumumab monotherapy in Japanese patients with metastatic colorectal cancer. | Japanese journal of clinical oncology 20090501 |
| Activity of S-1 in advanced or recurrent gastric cancer patients after failure of prior chemotherapy, including irinotecan + cisplatin or fluorouracil (except S-1). | Japanese journal of clinical oncology 20090501 |
| PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090501 |
| Medical Oncology: IROX as second-line therapy for metastatic colorectal cancer. | Nature reviews. Clinical oncology 20090501 |
| Retrospective analysis of S-1 monotherapy in patients with metastatic colorectal cancer after failure to fluoropyrimidine and irinotecan or to fluoropyrimidine, irinotecan and oxaliplatin. | Japanese journal of clinical oncology 20090501 |
| Chemotherapy with targeted agents for the treatment of metastatic colorectal cancer. | The oncologist 20090501 |
| High therapeutic effectiveness of postoperative irinotecan chemotherapy in a typical case of radiographically and pathologically diagnosed pleuropulmonary blastoma. | Journal of pediatric hematology/oncology 20090501 |
| Novel camptothecin derivatives as topoisomerase I inhibitors. | Expert opinion on therapeutic patents 20090501 |
| UGT1A1*28 genotype predicts gastrointestinal toxicity in patients treated with intermediate-dose irinotecan. | Pharmacogenomics 20090501 |
| [The progress of second-line chemotherapy and molecular targeting agents in gastric cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090501 |
| [Chemotherapy for breast cancer refractory to anthracycline, taxane or trastuzumab]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090501 |
| [Evaluation of irinotecan hydrochloride (CPT-11) and trastuzumab combination therapy as salvage treatment in patients with HER2 overexpressing metastatic breast cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090501 |
| [A case of recurrent endocrine cell carcinoma of the common bile duct successfully treated by hepatic artery infusion with CPT-11 and CDDP]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090501 |
| [CDDP+CPT-11 therapy is useful for stage IVb esophageal small cell carcinoma]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090501 |
| Novel developments in angiogenesis cancer therapy. | Current oncology (Toronto, Ont.) 20090501 |
| Clinical use of pharmacogenomic tests in 2009. | The Clinical biochemist. Reviews 20090501 |
| TP53 mutations predict disease control in metastatic colorectal cancer treated with cetuximab-based chemotherapy. | British journal of cancer 20090421 |
| Increased topoisomerase IIalpha expression in colorectal cancer is associated with advanced disease and chemotherapeutic resistance via inhibition of apoptosis. | Cancer letters 20090418 |
| Phase 1 study of oxaliplatin and irinotecan in pediatric patients with refractory solid tumors: a children's oncology group study. | Cancer 20090415 |
| Second-line chemotherapy in advanced and metastatic CRC. | The Cochrane database of systematic reviews 20090415 |
| Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, fluorouracil, and leucovorin in stage III colon cancer: Cancer and Leukemia Group B Protocol 89803. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090410 |
| Characteristics and outcomes of patients with advanced non-small-cell lung cancer who declined to participate in randomised clinical chemotherapy trials. | British journal of cancer 20090407 |
| Differing deregulation of EGFR and downstream proteins in primary colorectal cancer and related metastatic sites may be clinically relevant. | British journal of cancer 20090407 |
| Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. | The New England journal of medicine 20090402 |
| 'Natural history' of complete cytoreductive surgery with hyperthermic intraperitoneal chemotherapy. | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20090401 |
| A multi-center phase II study of oxaliplatin, irinotecan, and capecitabine in advanced gastric/gastroesophageal junction carcinoma. | Cancer chemotherapy and pharmacology 20090401 |
| Phase I study of capecitabine in combination with cisplatin and irinotecan in patients with advanced solid malignancies. | Investigational new drugs 20090401 |
| A dose finding and pharmacokinetic study of capecitabine in combination with oxaliplatin and irinotecan in metastatic colorectal cancer. | Cancer chemotherapy and pharmacology 20090401 |
| Yttrium-90 microsphere radioembolization for the treatment of liver malignancies: a structured meta-analysis. | European radiology 20090401 |
| Lack of stability of topotecan in heart tissue homogenates: is it an analytical dilemma or a real phenomenon? | Biomedical chromatography : BMC 20090401 |
| Phase II trial of two different irinotecan schedules with pharmacokinetic analysis in patients with recurrent glioma: North Central Cancer Treatment Group results. | Journal of neuro-oncology 20090401 |
| Two-stage hepatectomy (R0) with portal vein ligation--towards curing patients with extended bilobular colorectal liver metastases. | International journal of colorectal disease 20090401 |
| Shifting to first-line regimen after previous failure of irinotecan and oxaliplatin containing chemotherapies in unresectable metastatic colorectal cancer: a retrospective study of case analysis. | International journal of colorectal disease 20090401 |
| Organic anion-transporting polypeptide 1B1 mediates transport of Gimatecan and BNP1350 and can be inhibited by several classic ATP-binding cassette (ABC) B1 and/or ABCG2 inhibitors. | Drug metabolism and disposition: the biological fate of chemicals 20090401 |
| Phase II trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) as first-line treatment for advanced gastric cancer. | Anti-cancer drugs 20090401 |
| Gemcitabine, irinotecan and celecoxib in patients with biliary cancer. | Anti-cancer drugs 20090401 |
| A phase III randomised trial of LV5FU2 + irinotecan versus LV5FU2 alone in adjuvant high-risk colon cancer (FNCLCC Accord02/FFCD9802). | Annals of oncology : official journal of the European Society for Medical Oncology 20090401 |
| Need for a new treatment strategy: leptomeningeal carcinomatosis from gastric cancer. | Anti-cancer drugs 20090401 |
| Synthesis of new camptothecin analogs with improved antitumor activities. | Bioorganic & medicinal chemistry letters 20090401 |
| Inhibition of P-glycoprotein-mediated docetaxel efflux sensitizes ovarian cancer cells to concomitant docetaxel and SN-38 exposure. | Anti-cancer drugs 20090401 |
| Irinotecan-induced ovarian follicular apoptosis is attenuated by deleting the kinase domain of death-associated protein kinase. | International journal of oncology 20090401 |
| Phase I study of combination chemotherapy with irinotecan hydrochloride and nedaplatin for cervical squamous cell carcinoma: Japanese gynecologic oncology group study. | Oncology reports 20090401 |
| NDRG1 is down-regulated in the early apoptotic event induced by camptothecin analogs: the potential role in proteolytic activation of PKC delta and apoptosis. | Proteomics 20090401 |
| Toxic effects and their management: daily clinical challenges in the treatment of colorectal cancer. | Nature reviews. Clinical oncology 20090401 |
| 10 years of NICE: still growing and still controversial. | The Lancet. Oncology 20090401 |
| [Colorectal cancers: prognostic and predictive factors of response to treatment]. | Bulletin du cancer 20090401 |
| The Aurora kinase inhibitor SNS-314 shows broad therapeutic potential with chemotherapeutics and synergy with microtubule-targeted agents in a colon carcinoma model. | Molecular cancer therapeutics 20090401 |
| Local enzymatic hydrolysis of an endogenously generated metabolite can enhance CPT-11 anticancer efficacy. | Molecular cancer therapeutics 20090401 |
| [Risk associated with severe hematological toxicity in patients with advanced or recurrent gastric cancer receiving primary combination chemotherapy of cisplatin and S-1 or cisplatin and irinotecan hydrochloride]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090401 |
| UGT1A1*6 polymorphism is most predictive of severe neutropenia induced by irinotecan in Japanese cancer patients. | International journal of clinical oncology 20090401 |
| Surgical cytoreduction and intraperitoneal chemotherapy for peritoneal carcinomatosis arising from the appendix. | Canadian journal of surgery. Journal canadien de chirurgie 20090401 |
| What's new in ... colorectal cancer. Meaningful progress in therapy options. | JAAPA : official journal of the American Academy of Physician Assistants 20090401 |
| [Correlation of chemosensitivity measured by histoculture drug response assay to expression of multidrug resistance genes and proteins in gastric cancer]. | Ai zheng = Aizheng = Chinese journal of cancer 20090401 |
| Cetuximab-associated pulmonary toxicity. | Clinical colorectal cancer 20090401 |
| Catalytic bioscavengers against toxic esters, an alternative approach for prophylaxis and treatments of poisonings. | Acta naturae 20090401 |
| Mucinous histology predicts for poor response rate and overall survival of patients with colorectal cancer and treated with first-line oxaliplatin- and/or irinotecan-based chemotherapy. | British journal of cancer 20090324 |
| Irinotecan toxicity: genes or intestinal microflora? | British journal of cancer 20090324 |
| Phase II trial of irinotecan and carboplatin for extensive or relapsed small-cell lung cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090320 |
| The topoisomerase I poison CPT-11 enhances the effect of the aurora B kinase inhibitor AZD1152 both in vitro and in vivo. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090315 |
| Phase I trial of oral irinotecan and temozolomide for children with relapsed high-risk neuroblastoma: a new approach to neuroblastoma therapy consortium study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090310 |
| Relation between outcomes and localisation of p-mTOR expression in gastric cancer. | British journal of cancer 20090310 |
| Biomarker analysis in stage III-IV (M0) gastric cancer patients who received curative surgery followed by adjuvant 5-fluorouracil and cisplatin chemotherapy: epidermal growth factor receptor (EGFR) associated with favourable survival. | British journal of cancer 20090310 |
| Effect of P-glycoprotein inhibitor, verapamil, on oral bioavailability and pharmacokinetics of irinotecan in rats. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090302 |
| Impact, mechanisms, and novel chemotherapy strategies for overcoming resistance to anthracyclines and taxanes in metastatic breast cancer. | Breast cancer research and treatment 20090301 |
| Neurosurgical management and postoperative whole-brain radiotherapy for colorectal cancer patients with symptomatic brain metastases. | Journal of cancer research and clinical oncology 20090301 |
| A phase I study of combination therapy with S-1 and irinotecan (CPT-11) in patients with advanced colorectal cancer. | Journal of cancer research and clinical oncology 20090301 |
| Metronomic scheduling of imatinib abrogates clonogenicity of neuroblastoma cells and enhances their susceptibility to selected chemotherapeutic drugs in vitro and in vivo. | International journal of cancer 20090301 |
| Weekly high-dose 5-fluorouracil as a 24-h infusion and sodium folinic acid (AIO regimen) plus irinotecan in patients with locally advanced nonresectable and metastatic adenocarcinoma or squamous cell carcinoma of the oesophagus: a phase II trial. | Anti-cancer drugs 20090301 |
| Weekly docetaxel, cisplatin, and irinotecan (TPC): results of a multicenter phase II trial in patients with metastatic esophagogastric cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20090301 |
| Molecular cytogenetic evaluation of the mechanism of micronuclei formation induced by camptothecin, topotecan, and irinotecan. | Environmental and molecular mutagenesis 20090301 |
| Should irinotecan or etoposide be used in combination with carboplatin for small cell lung cancer? | Nature clinical practice. Oncology 20090301 |
| Impact of Fc{gamma}RIIa-Fc{gamma}RIIIa polymorphisms and KRAS mutations on the clinical outcome of patients with metastatic colorectal cancer treated with cetuximab plus irinotecan. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090301 |
| Long-term outcome of initially unresectable metastatic colorectal cancer patients treated with 5-fluorouracil/leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) followed by radical surgery of metastases. | Annals of surgery 20090301 |
| Successful treatment of small-cell lung cancer with irinotecan in a hemodialysis patient with end-stage renal disease. | The Korean journal of internal medicine 20090301 |
| Using pharmacologic data to plan clinical treatments for patients with peritoneal surface malignancy. | Current drug discovery technologies 20090301 |
| FDA review of a panitumumab (Vectibix) clinical trial for first-line treatment of metastatic colorectal cancer. | The oncologist 20090301 |
| Manifestation of alveolar rhabdomyosarcoma as primary cutaneous lesions in a neonate with Beckwith-Wiedemann syndrome. | Journal of pediatric surgery 20090301 |
| [Association of radiotherapy and chemotherapy-targeted therapies in glioblastomas]. | Bulletin du cancer 20090301 |
| Ethnic differences in drug metabolism and toxicity from chemotherapy. | Expert opinion on drug metabolism & toxicology 20090301 |
| Development of cell-cycle inhibitors for cancer therapy. | Current oncology (Toronto, Ont.) 20090301 |
| Hypertrophy of the non-embolized liver after chemotherapy. | HPB : the official journal of the International Hepato Pancreato Biliary Association 20090301 |
| Activation of p73 and induction of Noxa by DNA damage requires NF-kappa B. | Aging 20090301 |
| Marked activity of irinotecan and rapamycin combination toward colon cancer cells in vivo and in vitro is mediated through cooperative modulation of the mammalian target of rapamycin/hypoxia-inducible factor-1alpha axis. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090215 |
| Expression of human organic cation transporter 3 in kidney carcinoma cell lines increases chemosensitivity to melphalan, irinotecan, and vincristine. | Cancer research 20090215 |
| Complete cytoreductive surgery plus intraperitoneal chemohyperthermia with oxaliplatin for peritoneal carcinomatosis of colorectal origin. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090210 |
| A randomized phase IIIB trial of chemotherapy, bevacizumab, and panitumumab compared with chemotherapy and bevacizumab alone for metastatic colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090210 |
| Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090210 |
| The risk of febrile neutropenia in patients with non-small-cell lung cancer treated with docetaxel: a systematic review and meta-analysis. | British journal of cancer 20090210 |
| Inhibition of Akt signaling by SN-38 induces apoptosis in cervical cancer. | Cancer letters 20090208 |
| Phase I clinical and pharmacokinetic study of oxaliplatin, irinotecan and capecitabine. | Cancer chemotherapy and pharmacology 20090201 |
| Combination chemotherapy of biweekly irinotecan (CPT-11) plus tegafur/uracil (UFT) and leucovorin (LV) for patients with metastatic colorectal cancer: phase I/II study in Japanese patients. | Cancer chemotherapy and pharmacology 20090201 |
| Enterohepatic recirculation model of irinotecan (CPT-11) and metabolite pharmacokinetics in patients with glioma. | Cancer chemotherapy and pharmacology 20090201 |
| Phase I/II pharmacokinetic and pharmacogenomic study of UGT1A1 polymorphism in elderly patients with advanced non-small cell lung cancer treated with irinotecan. | Clinical pharmacology and therapeutics 20090201 |
| Randomized study of weekly irinotecan plus high-dose 5-fluorouracil (FUIRI) versus biweekly irinotecan plus 5-fluorouracil/leucovorin (FOLFIRI) as first-line chemotherapy for patients with metastatic colorectal cancer: a Spanish Cooperative Group for the Treatment of Digestive Tumors Study. | Annals of oncology : official journal of the European Society for Medical Oncology 20090201 |
| Experience with irinotecan for the treatment of malignant glioma. | Neuro-oncology 20090201 |
| Evaluation of novel histone deacetylase inhibitors as therapeutic agents for colorectal adenocarcinomas compared to established regimens with the histoculture drug response assay. | International journal of colorectal disease 20090201 |
| Arterial hypertension correlates with clinical outcome in colorectal cancer patients treated with first-line bevacizumab. | Annals of oncology : official journal of the European Society for Medical Oncology 20090201 |
| Two different first-line 5-fluorouracil regimens with or without oxaliplatin in patients with metastatic colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20090201 |
| Efficacy, safety and patterns of response and recurrence in patients with recurrent high-grade gliomas treated with bevacizumab plus irinotecan. | Journal of neuro-oncology 20090201 |
| Major SNP (Q141K) variant of human ABC transporter ABCG2 undergoes lysosomal and proteasomal degradations. | Pharmaceutical research 20090201 |
| Close association of UGT1A9 IVS1+399C>T with UGT1A1*28, *6, or *60 haplotype and its apparent influence on 7-ethyl-10-hydroxycamptothecin (SN-38) glucuronidation in Japanese. | Drug metabolism and disposition: the biological fate of chemicals 20090201 |
| Synchronous hepatic metastases from colon cancer: changing treatment strategies and results of surgical intervention. | Annals of surgical oncology 20090201 |
| Response to chemotherapy predicts survival following resection of hepatic colo-rectal metastases in patients treated with neoadjuvant therapy. | Journal of surgical oncology 20090201 |
| Evolution of nonsurgical therapy for colorectal cancer. | Nature clinical practice. Gastroenterology & hepatology 20090201 |
| Dasatinib-induced autophagy is enhanced in combination with temozolomide in glioma. | Molecular cancer therapeutics 20090201 |
| Irinotecan in cancer patients with end-stage renal failure. | The Annals of pharmacotherapy 20090201 |
| Phase I and pharmacokinetic study of tegafur-uracil/leucovorin combined with 5-fluorouracil/leucovorin and irinotecan in patients with advanced colorectal cancer. | American journal of clinical oncology 20090201 |
| Quercetin and its derivatives: synthesis, pharmacological uses with special emphasis on anti-tumor properties and prodrug with enhanced bio-availability. | Anti-cancer agents in medicinal chemistry 20090201 |
| EFEMP1 expression promotes in vivo tumor growth in human pancreatic adenocarcinoma. | Molecular cancer research : MCR 20090201 |
| [A case of lung adenocarcinoma of pancoast type successfully treated with concurrent chemoradiotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090201 |
| [A case of recurrence after curative total gastrectomy for gastric cancer successfully treated by combination chemotherapy with CPT-11 and CDDP]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090201 |
| Phase I study of daily S-1 combined with weekly irinotecan in patients with advanced non-small cell lung cancer. | International journal of clinical oncology 20090201 |
| Role of glucocorticoid receptor in the regulation of cellular sensitivity to irinotecan hydrochloride. | Journal of pharmacological sciences 20090201 |
| The CAIRO and FOCUS studies: which lesson is to be learned? | The oncologist 20090201 |
| Definitive chemoradiotherapy with capecitabine and cisplatin in patients with esophageal cancer: a pilot study. | Journal of Korean medical science 20090201 |
| The European contribution to 'Sugarbaker's protocol' for the treatment of colorectal peritoneal carcinomatosis. | Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 20090201 |
| Capecitabine and irinotecan with and without bevacizumab for advanced colorectal cancer patients. | World journal of gastroenterology 20090128 |
| Phase II study and biomarker analysis of cetuximab combined with modified FOLFOX6 in advanced gastric cancer. | British journal of cancer 20090127 |
| Toxicity associated with combination oxaliplatin plus fluoropyrimidine with or without cetuximab in the MRC COIN trial experience. | British journal of cancer 20090127 |
| Deficient mismatch repair system in patients with sporadic advanced colorectal cancer. | British journal of cancer 20090127 |
| gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity. | Cancer research 20090115 |
| Safety, pharmacokinetics, and efficacy of CPX-1 liposome injection in patients with advanced solid tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090115 |
| A case report of endocrine cell carcinoma in the sigmoid colon with inferior mesenteric vein tumor embolism. | World journal of gastroenterology 20090114 |
| Antiangiogenic drugs in ovarian cancer. | British journal of cancer 20090113 |
| Paclitaxel and carboplatin vs gemcitabine and vinorelbine in patients with adeno- or undifferentiated carcinoma of unknown primary: a randomised prospective phase II trial. | British journal of cancer 20090113 |
| Irinotecan plus carboplatin for patients with carcinoma of unknown primary site. | British journal of cancer 20090113 |
| Addition of bevacizumab to fluorouracil-based first-line treatment of metastatic colorectal cancer: pooled analysis of cohorts of older patients from two randomized clinical trials. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090110 |
| Integrated pharmacogenetic prediction of irinotecan pharmacokinetics and toxicity in patients with advanced non-small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20090101 |
| Is the pathobiology of chemotherapy-induced alimentary tract mucositis influenced by the type of mucotoxic drug administered? | Cancer chemotherapy and pharmacology 20090101 |
| A phase II study of pegylated-camptothecin (pegamotecan) in the treatment of locally advanced and metastatic gastric and gastro-oesophageal junction adenocarcinoma. | Cancer chemotherapy and pharmacology 20090101 |
| Bevacizumab plus FOLFIRI or FOLFOX as third-line or later treatment in patients with metastatic colorectal cancer after failure of 5-fluorouracil, irinotecan, and oxaliplatin: a retrospective analysis. | Medical oncology (Northwood, London, England) 20090101 |
| Primary small cell carcinoma of the breast. | Breast cancer (Tokyo, Japan) 20090101 |
| Multiagent chemotherapy for isolated colorectal liver metastases: a single-centered retrospective study. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20090101 |
| How can we ameliorate irinotecan-associated diarrhea in children with poor compliance for oral cephalosporin? | Pediatric blood & cancer 20090101 |
| Comparative analysis of temozolomide (TMZ) versus 1,3-bis (2-chloroethyl)-1 nitrosourea (BCNU) in newly diagnosed glioblastoma multiforme (GBM) patients. | Journal of neuro-oncology 20090101 |
| 90-kDa heat shock protein inhibition abrogates the topoisomerase I poison-induced G2/M checkpoint in p53-null tumor cells by depleting Chk1 and Wee1. | Molecular pharmacology 20090101 |
| Antiangiogenic therapy using bevacizumab in recurrent high-grade glioma: impact on local control and patient survival. | Journal of neurosurgery 20090101 |
| Review article: benefits and risks of chemotherapy in elderly patients with metastatic colorectal cancer. | Alimentary pharmacology & therapeutics 20090101 |
| Preoperative chemotherapy does not increase morbidity or mortality of hepatic resection for colorectal cancer metastases. | Annals of surgical oncology 20090101 |
| In vitro activity of bortezomib in cultures of patient tumour cells--potential utility in haematological malignancies. | Medical oncology (Northwood, London, England) 20090101 |
| Bevacizumab plus irinotecan in the treatment patients with progressive recurrent malignant brain tumours. | Acta oncologica (Stockholm, Sweden) 20090101 |
| Diflomotecan, a promising homocamptothecin for cancer therapy. | Expert opinion on investigational drugs 20090101 |
| A pilot human evaluation of a formulation of irinotecan and hyaluronic acid in 5-fluorouracil-refractory metastatic colorectal cancer patients. | Chemotherapy 20090101 |
| The effect of Saccharomyces boulardii on reducing irinotecan-induced intestinal mucositis and diarrhea. | Medical oncology (Northwood, London, England) 20090101 |
| Phase II study of UFT with leucovorin plus hepatic arterial infusion with irinotecan, 5-fluorouracil and leucovorin for non-resectable liver metastases of colorectal cancer. | Chemotherapy 20090101 |
| Phase 1 and pharmacokinetic study of concurrent carboplatin and irinotecan in subjects aged 1 to 21 years with refractory solid tumors. | Cancer 20090101 |
| Repeated transarterial chemoembolization in the treatment of liver metastases of colorectal cancer: prospective study. | Radiology 20090101 |
| Patterns of chemotherapy-induced hepatic injury and their implications for patients undergoing liver resection for colorectal liver metastases. | Journal of hepato-biliary-pancreatic surgery 20090101 |
| Lessons learned from independent central review. | European journal of cancer (Oxford, England : 1990) 20090101 |
| Intermittent therapy in the palliative treatment of metastatic colorectal cancer. | Expert review of anticancer therapy 20090101 |
| Is overexpression of HER-2 a predictor of prognosis in colorectal cancer? | BMC cancer 20090101 |
| Recommendations from the EGAPP Working Group: can UGT1A1 genotyping reduce morbidity and mortality in patients with metastatic colorectal cancer treated with irinotecan? | Genetics in medicine : official journal of the American College of Medical Genetics 20090101 |
| Can UGT1A1 genotyping reduce morbidity and mortality in patients with metastatic colorectal cancer treated with irinotecan? An evidence-based review. | Genetics in medicine : official journal of the American College of Medical Genetics 20090101 |
| Chemotherapy for small-bowel Adenocarcinoma at a single institution. | Surgery today 20090101 |
| The clinical benefit of bevacizumab in metastatic colorectal cancer is independent of K-ras mutation status: analysis of a phase III study of bevacizumab with chemotherapy in previously untreated metastatic colorectal cancer. | The oncologist 20090101 |
| Anti-epidermal growth factor receptor monotherapy in the treatment of metastatic colorectal cancer: where are we today? | The oncologist 20090101 |
| Pharmacogenetics and pharmacogenomics of anticancer agents. | CA: a cancer journal for clinicians 20090101 |
| The role of capecitabine in the management of tumors of the digestive system. | Reviews on recent clinical trials 20090101 |
| Treatment of colorectal liver metastases: a review. | Reviews on recent clinical trials 20090101 |
| [Lung cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090101 |
| [Advanced gastric cancer showing complete response to neoadjuvant chemotherapy with CPT-11 and S-1-a case report]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090101 |
| [A case of simultaneous double cancers with multiple liver metastases responding to S-1+CPT-11]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090101 |
| The intraportal injection model: a practical animal model for hepatic metastases and tumor cell dissemination in human colon cancer. | BMC cancer 20090101 |
| Clinical benefit of new targeted agents in phase I trials in patients with advanced colorectal cancer. | Oncology 20090101 |
| Advanced gastric cancer patient with peritonitis carcinomatosa successfully treated with a combination therapy of paclitaxel and TS-1, but relapsed with multiple bone metastasis and died from rapidly progressive meningitis carcinomatosa--advanced gastric cancer with metachronous peritonitis carcinomatosa and meningitis carcinomatosa. | Internal medicine (Tokyo, Japan) 20090101 |
| Scrotal metastases from colorectal carcinoma: a case report. | Cases journal 20090101 |
| Does celecoxib have a role in the treatment of patients with colorectal cancer? | Clinical colorectal cancer 20090101 |
| Role of pharmacogenetics as predictive biomarkers of response and/or toxicity in the treatment of colorectal cancer. | Clinical colorectal cancer 20090101 |
| The potential role and application of PARP inhibitors in cancer treatment. | British medical bulletin 20090101 |
| Centrosome-associated regulators of the G(2)/M checkpoint as targets for cancer therapy. | Molecular cancer 20090101 |
| Management of skin rash during EGFR-targeted monoclonal antibody treatment for gastrointestinal malignancies: Canadian recommendations. | Current oncology (Toronto, Ont.) 20090101 |
| Updates in Gastrointestinal Oncology - insights from the 2008 44th annual meeting of the American Society of Clinical Oncology. | Journal of hematology & oncology 20090101 |
| Curative resection of a primarily unresectable acinar cell carcinoma of the pancreas after chemotherapy. | World journal of surgical oncology 20090101 |
| Acute and long-term gastrointestinal consequences of chemotherapy. | Best practice & research. Clinical gastroenterology 20090101 |
| The role of MMP7 and its cross-talk with the FAS/FASL system during the acquisition of chemoresistance to oxaliplatin. | PloS one 20090101 |
| Immunotherapy for liver tumors: present status and future prospects. | Journal of biomedical science 20090101 |
| Stereotactic radiosurgery for glioblastoma: retrospective analysis. | Radiation oncology (London, England) 20090101 |
| The role of UFT in metastatic colorectal cancer. | Oncology 20090101 |
| Clinical significance of UDP-glucuronosyltransferase 1A1*6 for toxicities of combination chemotherapy with irinotecan and cisplatin in gynecologic cancers: a prospective multi-institutional study. | Oncology 20090101 |
| Phase I/II study of twenty-four-hour infusion of irinotecan in combination with oral UFT plus leucovorin for metastatic colorectal cancer. | Oncology 20090101 |
| Novel regimens of capecitabine alone and combined with irinotecan and bevacizumab in colorectal cancer xenografts. | Anticancer research 20090101 |
| Treatment of recurrent malignant gliomas with fotemustine monotherapy: impact of dose and correlation with MGMT promoter methylation. | BMC cancer 20090101 |
| Genomic and oncoproteomic advances in detection and treatment of colorectal cancer. | World journal of surgical oncology 20090101 |
| Microsatellite instability: a predictive marker in metastatic colorectal cancer? | Targeted oncology 20090101 |
| Efficacy and safety of capecitabine and oxaliplatin combination as second-line treatment in advanced colorectal cancer. | American journal of therapeutics 20090101 |
| PDGF-C induces maturation of blood vessels in a model of glioblastoma and attenuates the response to anti-VEGF treatment. | PloS one 20090101 |
| A retrospective analysis of second-line chemotherapy in patients with advanced gastric cancer. | BMC cancer 20090101 |
| Update in antiepidermal growth factor receptor therapy in the management of metastatic colorectal cancer. | Journal of oncology 20090101 |
| Feasibility study of biweekly capecitabine, oxaliplatin, and irinotecan in patients with untreated advanced gastric cancer. | Tumori 20090101 |
| Cetuximab in combination with irinotecan/5-fluorouracil/folinic acid (FOLFIRI) in the initial treatment of metastatic colorectal cancer: a multicentre two-part phase I/II study. | BMC cancer 20090101 |
| Intra-arterial hepatic chemoembolization (TACE) of liver metastases from ocular melanoma with slow-release irinotecan-eluting beads. Early results of a phase II clinical study. | In vivo (Athens, Greece) 20090101 |
| Revisiting perioperative chemotherapy: the critical importance of targeting residual cancer prior to wound healing. | BMC cancer 20090101 |
| Capecitabine plus Irinotecan (XELIRI regimen) compared to 5-FU/LV plus Irinotecan (FOLFIRI regimen) as neoadjuvant treatment for patients with unresectable liver-only metastases of metastatic colorectal cancer: a randomised prospective phase II trial. | BMC cancer 20090101 |
| Individualized therapies in colorectal cancer: KRAS as a marker for response to EGFR-targeted therapy. | Journal of hematology & oncology 20090101 |
| Vandetanib (Zactima, ZD6474) antagonizes ABCC1- and ABCG2-mediated multidrug resistance by inhibition of their transport function. | PloS one 20090101 |
| A population-based clinical trial of irinotecan and Carboplatin. | Journal of oncology 20090101 |
| Possible treatment strategies for triple-negative breast cancer on the basis of molecular characteristics. | Breast cancer (Tokyo, Japan) 20090101 |
| Pharmacogenetics in chemotherapy of colorectal cancer. | Best practice & research. Clinical gastroenterology 20090101 |
| The role side effects play in the choice of antiepileptic therapy in brain tumor-related epilepsy: a comparative study on traditional antiepileptic drugs versus oxcarbazepine. | Journal of experimental & clinical cancer research : CR 20090101 |
| Clinical Efficacy and Toxicity of Anti-EGFR Therapy in Common Cancers. | Journal of oncology 20090101 |
| Early assessment of therapeutic response using FDG PET in small cell lung cancer. | Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20090101 |
| Role of oxaliplatin in the treatment of colorectal cancer. | Therapeutics and clinical risk management 20090101 |
| A gene expression predictor of response to EGFR-targeted therapy stratifies progression-free survival to cetuximab in KRAS wild-type metastatic colorectal cancer. | BMC cancer 20090101 |
| Treatment of gastric cancer cells with 5-fluorouracil/leucovorin and irinotecan induces distinct alterations in the mRNA expression of the apoptosis-related genes, including the novel gene BCL2L12. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20090101 |
| A phase II experience with neoadjuvant irinotecan (CPT-11), 5-fluorouracil (5-FU) and leucovorin (LV) for colorectal liver metastases. | BMC cancer 20090101 |
| A novel information retrieval model for high-throughput molecular medicine modalities. | Cancer informatics 20090101 |
| [Study into the use of cetuximab in metastatic colorectal cancer in a third level hospital]. | Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20090101 |
| Radiotherapy quality assurance review in a multi-center randomized trial of limited-disease small cell lung cancer: the Japan Clinical Oncology Group (JCOG) trial 0202. | Radiation oncology (London, England) 20090101 |
| Outcome of recurrent and metastatic small cell carcinoma of the bladder. | BMC urology 20090101 |
| Primary treatment of diabetic macular edema. | Clinical interventions in aging 20090101 |
| Albumin-bound formulation of paclitaxel (Abraxane ABI-007) in the treatment of breast cancer. | International journal of nanomedicine 20090101 |
| Systemic disease-induced salivary biomarker profiles in mouse models of melanoma and non-small cell lung cancer. | PloS one 20090101 |
| Synthetic lethal RNAi screening identifies sensitizing targets for gemcitabine therapy in pancreatic cancer. | Journal of translational medicine 20090101 |
| Antibodies to prion protein inhibit human colon cancer cell growth. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20090101 |
| [Bevacizumab in combination with capecitabine and irinotecan (XELIRI) in treatment of metastatic colorectal cancer]. | Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 20090101 |
| Oncolytic adenovirus mediated Survivin knockdown by RNA interference suppresses human colorectal carcinoma growth in vitro and in vivo. | Journal of experimental & clinical cancer research : CR 20090101 |
| [Cetuximab and irinotecan for the treatment of metastatic colorectal cancer--pilot results from Masaryk Memorial Cancer Institute]. | Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 20090101 |
| Anthracycline extravasation injuries: management with dexrazoxane. | Therapeutics and clinical risk management 20090101 |
| A novel method, digital genome scanning detects KRAS gene amplification in gastric cancers: involvement of overexpressed wild-type KRAS in downstream signaling and cancer cell growth. | BMC cancer 20090101 |
| [Palliative treatment for colorectal cancer]. | Onkologie 20090101 |
| [Neoadjuvant and surgical treatment for rectal cancer]. | Onkologie 20090101 |
| Anti-tumor activity of patient-derived NK cells after cell-based immunotherapy--a case report. | Journal of translational medicine 20090101 |
| Proneoplastic effects of PGE2 mediated by EP4 receptor in colorectal cancer. | BMC cancer 20090101 |
| Comparison of colorectal and gastric cancer: survival and prognostic factors. | Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20090101 |
| Response of the primary tumor in symptomatic and asymptomatic stage IV colorectal cancer to combined interventional endoscopy and palliative chemotherapy. | BMC cancer 20090101 |
| Effects of Japanese herbal medicine, Kampo, on human UGT1A1 activity. | Drug metabolism and pharmacokinetics 20090101 |
| Dynamics of different-sized solid-state nanocrystals as tracers for a drug-delivery system in the interstitium of a human tumor xenograft. | Breast cancer research : BCR 20090101 |
| Clinical Significance of Skin Toxicity due to EGFR-Targeted Therapies. | Journal of oncology 20090101 |
| Histopathological effects of cisplatin, doxorubicin and 5-flurouracil (5-FU) on the liver of male albino rats. | International journal of biological sciences 20090101 |
| Synthesis and in vivo antitumor efficacy of PEGylated poly(l-lysine) dendrimer-camptothecin conjugates. | Molecular pharmaceutics 20090101 |
| Carbonic anhydrase 9 is a predictive marker of survival benefit from lower dose of bevacizumab in patients with previously treated metastatic colorectal cancer. | BMC cancer 20090101 |
| Neoadjuvant chemotherapy followed by hepatectomy for primarily resectable colorectal cancer liver metastases. | Hepato-gastroenterology 20090101 |
| Phase IV study of bevacizumab in combination with infusional fluorouracil, leucovorin and irinotecan (FOLFIRI) in first-line metastatic colorectal cancer. | Oncology 20090101 |
| Evolving treatment of advanced colon cancer. | Annual review of medicine 20090101 |
| Allometric scaling of a metabolically complex camptothecin analog: differences in scaling of irinotecan and its active metabolite, SN-38. | Arzneimittel-Forschung 20090101 |
| Anti-EGFR-Targeted Therapy for Esophageal and Gastric Cancers: An Evolving Concept. | Journal of oncology 20090101 |
| Improving Response Rates to EGFR-Targeted Therapies for Head and Neck Squamous Cell Carcinoma: Candidate Predictive Biomarkers and Combination Treatment with Src Inhibitors. | Journal of oncology 20090101 |
| [Monoclonal antibodies therapies for colorectal cancer: cétuximab, panitumumab and bevacizumab]. | Revue medicale de Liege 20090101 |
| ABT-869, a promising multi-targeted tyrosine kinase inhibitor: from bench to bedside. | Journal of hematology & oncology 20090101 |
| Functional expression of a DNA-topoisomerase IB from Cryptosporidium parvum. | Journal of biomedicine & biotechnology 20090101 |
| Evaluation of the possible benefits of post-radiotherapy surgery after concomitant chemoradiotherapy with a new radio-sensitizing regimen (irinotecan / CPT-11, interferon A2b and amifostine) for advanced-stage cervical carcinoma. Preliminary results of a pilot phase-II study. | Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20090101 |
| Epidermal growth factor receptor inhibition modulates the microenvironment by vascular normalization to improve chemotherapy and radiotherapy efficacy. | PloS one 20090101 |
| Multicenter safety study of mFOLFOX6 for unresectable advanced/recurrent colorectal cancer in elderly patients. | Journal of experimental & clinical cancer research : CR 20090101 |
| Skin rash associated with intravitreal bevacizumab in a patient with macular choroidal neovascularization. | Clinical ophthalmology (Auckland, N.Z.) 20090101 |
| [Pre-clinical study of combined aranosa, cisplatin and irinotecan in the treatment of experimental lung cancer]. | Voprosy onkologii 20090101 |
| Cardiovascular response to beta-adrenergic blockade or activation in 23 inbred mouse strains. | PloS one 20090101 |
| Hepatoid adenocarcinoma of the stomach - a different histology for not so different gastric adenocarcinoma: a case report. | International seminars in surgical oncology : ISSO 20090101 |
| Presence of activating KRAS mutations correlates significantly with expression of tumour suppressor genes DCN and TPM1 in colorectal cancer. | BMC cancer 20090101 |
| Tumor biology and cancer therapy - an evolving relationship. | Cell communication and signaling : CCS 20090101 |
| Xenograft models of head and neck cancers. | Head & neck oncology 20090101 |
| Association of cetuximab with adverse pulmonary events in cancer patients: a comprehensive review. | Journal of experimental & clinical cancer research : CR 20090101 |
| Advances in the pharmacological treatment of gastro-oesophageal cancer. | Drugs & aging 20090101 |
| Network-assisted protein identification and data interpretation in shotgun proteomics. | Molecular systems biology 20090101 |
| Plexin D1 is ubiquitously expressed on tumor vessels and tumor cells in solid malignancies. | BMC cancer 20090101 |
| Current available therapies and future directions in the treatment of malignant gliomas. | Biologics : targets & therapy 20090101 |
| EGFR targeted therapy in non-small cell lung cancer: potential role of cetuximab. | Biologics : targets & therapy 20090101 |
| UGT1A1, UGT1A6 and UGT1A7 genetic analysis: repercussion for irinotecan pharmacogenetics in the São Miguel Island Population (Azores, Portugal). | Molecular diagnosis & therapy 20090101 |
| Epidermal Growth Factor Receptor (EGFR) gene copy number (GCN) correlates with clinical activity of irinotecan-cetuximab in K-RAS wild-type colorectal cancer: a fluorescence in situ (FISH) and chromogenic in situ hybridization (CISH) analysis. | BMC cancer 20090101 |
| [Targeted biotherapy: a revolution in the management of patients with colorectal cancer?]. | Gastroenterologie clinique et biologique 20090101 |
| Effective monotherapy with amrubicin for a refractory extrapulmonary small-cell carcinoma of the liver. | Case reports in medicine 20090101 |
| Interactions between herbal medicines and prescribed drugs: an updated systematic review. | Drugs 20090101 |
| The drug-resistance to gefitinib in PTEN low expression cancer cells is reversed by irradiation in vitro. | Journal of experimental & clinical cancer research : CR 20090101 |
| Pharmacogenomics in chemotherapy for GI tract cancer. | Journal of gastroenterology 20090101 |
| Phase II study of S-1 combined with irinotecan (CPT-11) in patients with advanced colorectal cancer. | Oncology 20090101 |
| Networking of differentially expressed genes in human cancer cells resistant to methotrexate. | Genome medicine 20090101 |
| Meta-analysis of glioblastoma multiforme versus anaplastic astrocytoma identifies robust gene markers. | Molecular cancer 20090101 |
| The role of KRAS mutations in predicting the efficacy of cetuximab-plus-irinotecan therapy in irinotecan-refractory Korean metastatic colorectal cancer patients. | Oncology 20090101 |
| Recent advances in systemic therapy. When HER2 is not the target: advances in the treatment of HER2-negative metastatic breast cancer. | Breast cancer research : BCR 20090101 |
| Treatment of pancreatic cancer with epidermal growth factor receptor-targeted therapy. | Biologics : targets & therapy 20090101 |
| Current use and potential role of bevacizumab in the treatment of gastrointestinal cancers. | Biologics : targets & therapy 20090101 |
| Clinical research of Olanzapine for prevention of chemotherapy-induced nausea and vomiting. | Journal of experimental & clinical cancer research : CR 20090101 |
| Topoisomerase I but not thymidylate synthase is associated with improved outcome in patients with resected colorectal cancer treated with irinotecan containing adjuvant chemotherapy. | BMC cancer 20090101 |
| Single-step therapy -- feasibility and safety of simultaneous transarterial chemoembolization and radiofrequency ablation for hepatic malignancies. | In vivo (Athens, Greece) 20090101 |
| Bevacizumab plus FOLFIRI or FOLFOX in chemotherapy-refractory patients with metastatic colorectal cancer: a retrospective study. | BMC cancer 20090101 |
| Update and review of the multidisciplinary management of stage IV colorectal cancer with liver metastases. | World journal of surgical oncology 20090101 |
| Prognostic and therapeutic potential of nuclear receptors in head and neck squamous cell carcinomas. | Journal of oncology 20090101 |
| Drugs associated with more suicidal ideations are also associated with more suicide attempts. | PloS one 20090101 |
| Identification of a novel topoisomerase inhibitor effective in cells overexpressing drug efflux transporters. | PloS one 20090101 |
| [Targeted drugs for the treatment of disseminated colonic cancer]. | Vestnik Rossiiskoi akademii meditsinskikh nauk 20090101 |
| Multi-determinants analysis of molecular alterations for predicting clinical benefit to EGFR-targeted monoclonal antibodies in colorectal cancer. | PloS one 20090101 |
| An efficient targeted drug delivery through apotransferrin loaded nanoparticles. | PloS one 20090101 |
| Gemcitabine plus irinotecan as first-line weekly therapy in locally advanced and/or metastatic pancreatic cancer. | Oncology research 20090101 |
| Retroperitoneal abscess complicated with necrotizing fasciitis of the thigh in a patient with sigmoid colon cancer. | World journal of surgical oncology 20090101 |
| Alleviating effect of active hexose correlated compound (AHCC) for anticancer drug-induced side effects in non-tumor-bearing mice. | Journal of experimental therapeutics & oncology 20090101 |
| A pilot study of irinotecan combined with 5-fluorouracil and leucovorin for the treatment of Chinese patients with locally advanced and metastatic gastric cancer. | Tumori 20090101 |
| Targeting EGFR with photodynamic therapy in combination with Erbitux enhances in vivo bladder tumor response. | Molecular cancer 20090101 |
| Current understanding of the role of PPARγ in gastrointestinal cancers. | PPAR research 20090101 |
| Transarterial chemoembolisation (TACE) using irinotecan-loaded beads for the treatment of unresectable metastases to the liver in patients with colorectal cancer: an interim report. | World journal of surgical oncology 20090101 |
| Transarterial Chemoembolization of Metastatic Colorectal Carcinoma with Drug-Eluting Beads, Irinotecan (DEBIRI): Multi-Institutional Registry. | Journal of oncology 20090101 |
| Cytokine levels correlate with immune cell infiltration after anti-VEGF therapy in preclinical mouse models of breast cancer. | PloS one 20090101 |
| Docetaxel: its role in current and future treatments for advanced gastric cancer. | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20090101 |
| Vascular endothelial growth factor in children with neuroblastoma: a retrospective analysis. | Journal of experimental & clinical cancer research : CR 20090101 |
| Primary clear cell carcinoma of the peritoneum: report of two cases and a review of the literature. | European journal of gynaecological oncology 20090101 |
| Camptothecin and khat (Catha edulis Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines. | Molecular cancer 20090101 |
| Twenty-seven years of phase III trials for patients with extensive disease small-cell lung cancer: disappointing results. | PloS one 20090101 |
| Long-term disease-free survivor of metastatic large-cell neuroendocrine carcinoma of the lung treated with amrubicin and irinotecan. | Drug design, development and therapy 20090101 |
| Profiling critical cancer gene mutations in clinical tumor samples. | PloS one 20090101 |
| Acute coronary syndrome associated with continuous 5-Fluorouracil infusion in a patient with metastatic colorectal cancer-a case report with a discussion on this clinical dilemma. | Journal of gastrointestinal cancer 20090101 |
| Colon cancer and the elderly: from screening to treatment in management of GI disease in the elderly. | Best practice & research. Clinical gastroenterology 20090101 |
| Induction of apoptosis in HeLa cells by chloroform fraction of seed extracts of Nigella sativa. | Cancer cell international 20090101 |
| DCE-MRI assessment of the effect of vandetanib on tumor vasculature in patients with advanced colorectal cancer and liver metastases: a randomized phase I study. | Journal of angiogenesis research 20090101 |
| Chemo-diversion strategy for unresectable colorectal carcinoma: report of two cases. | Hepato-gastroenterology 20090101 |
| Enhancing effectiveness of the MDR-sensitive compound T138067 using advanced treatment with negative modulators of the drug-resistant protein survivin. | American journal of translational research 20090101 |
| Fesoterodine for the treatment of urinary incontinence and overactive bladder. | Therapeutics and clinical risk management 20090101 |
| A phase I study of pegylated liposomal doxorubicin and irinotecan in patients with solid tumors. | Chemotherapy 20090101 |
| Nodular regenerative hyperplasia secondary to neoadjuvant chemotherapy for colorectal liver metastases. | Case reports in medicine 20090101 |
| The effect on the small bowel of 5-FU and oxaliplatin in combination with radiation using a microcolony survival assay. | Radiation oncology (London, England) 20090101 |
| Expression of HIF-1alpha and VEGF in colorectal cancer: association with clinical outcomes and prognostic implications. | BMC cancer 20090101 |
| APRIL is a novel clinical chemo-resistance biomarker in colorectal adenocarcinoma identified by gene expression profiling. | BMC cancer 20090101 |
| Concerns about anti-angiogenic treatment in patients with glioblastoma multiforme. | BMC cancer 20090101 |
| Vascular Endothelial Growth Factor plus Epidermal Growth Factor Receptor Dual Targeted Therapy in Metastatic Colorectal Cancer: Synergy or Antagonism? | Journal of oncology 20090101 |
| Regulation of HIV-1 transcription in cells of the monocyte-macrophage lineage. | Retrovirology 20090101 |
| The GYMSSA trial: a prospective randomized trial comparing gastrectomy, metastasectomy plus systemic therapy versus systemic therapy alone. | Trials 20090101 |
| Histidine-rich glycoprotein can prevent development of mouse experimental glioblastoma. | PloS one 20090101 |
| Weekly paclitaxel for heavily treated advanced or recurrent gastric cancer refractory to fluorouracil, irinotecan, and cisplatin. | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20090101 |
| Diffuse cardiac lymphatic involvement by metastatic neuroendocrine carcinoma mimicking hypertrophic cardiomyopathy: a case report. | Cases journal 20090101 |
| Treatment of metastatic urachal adenocarcinoma in a young woman: a case report. | Cases journal 20090101 |
| The increasing role of pharmacogenetics in the treatment of gastrointestinal cancers. | Gastrointestinal cancer research : GCR 20090101 |
| Pharmacogenomic insights into treatment and management of statin-induced myopathy. | Genome medicine 20090101 |
| Dosage escalation study of S-1 and irinotecan in metronomic chemotherapy against advanced colorectal cancer. | The Kurume medical journal 20090101 |
| Adjuvant therapy in colon cancer. | Oncology 20090101 |
| The long and winding road to useful predictive factors for anti-EGFR therapy in metastatic colorectal carcinoma: the KRAS/BRAF pathway. | Oncology 20090101 |
| Long-term outcomes following hepatic resection and radiofrequency ablation of colorectal liver metastases. | HPB surgery : a world journal of hepatic, pancreatic and biliary surgery 20090101 |
| Irinotecan associated with cetuximab given every 2 weeks versus cetuximab weekly in metastatic colorectal cancer. | Journal of cancer research and therapeutics 20090101 |
| Preparation and characterization of poly lactide-co-glycolide nanoparticles of SN-38. | PDA journal of pharmaceutical science and technology 20090101 |
| InPACdb--Indian plant anticancer compounds database. | Bioinformation 20090101 |
| Irinotecan plus S-1 for liver metastases of gastric cancer. | Hepato-gastroenterology 20090101 |
| Concordance of KRAS/BRAF Mutation Status in Metastatic Colorectal Cancer before and after Anti-EGFR Therapy. | Journal of oncology 20090101 |
| Retrospectively comparative evaluation of the first- and second-line chemotherapy with campto and oxaliplatin combined with oral tegafur/uracil (UFT)/leucovorin (LV) in patients with metastatic colorectal cancer. | International surgery 20090101 |
| Screening of potential molecular targets for colorectal cancer therapy. | International journal of general medicine 20090101 |
| Chenopodium album prevents progression of cell growth and enhances cell toxicity in human breast cancer cell lines. | Oxidative medicine and cellular longevity 20090101 |
| Chemoradiotherapy in pancreatic carcinoma. | Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology 20090101 |
| Targeted therapies in the management of colorectal carcinoma: role of bevacizumab. | OncoTargets and therapy 20090101 |
| Current status of treatment of metastatic colorectal cancer with special reference to cetuximab and elderly patients. | OncoTargets and therapy 20090101 |
| Targeting cancers in the gastrointestinal tract: role of capecitabine. | OncoTargets and therapy 20090101 |
| First-line targeted therapies in the treatment of metastatic colorectal cancer - role of cetuximab. | OncoTargets and therapy 20090101 |
| Role of trabectedin in the treatment of soft tissue sarcoma. | OncoTargets and therapy 20090101 |
| Targeted therapy in the treatment of malignant gliomas. | OncoTargets and therapy 20090101 |
| Targeting colorectal cancer with anti-epidermal growth factor receptor antibodies: focus on panitumumab. | OncoTargets and therapy 20090101 |
| The ubiquitin-proteasome system as a molecular target in solid tumors: an update on bortezomib. | OncoTargets and therapy 20090101 |
| Palliative Benefits of the Multimodality Approach in the Re-treatment of Recurrent Malignant Glioma: Two Case Reports. | Indian journal of palliative care 20090101 |
| Temozolomide: The evidence for its therapeutic efficacy in malignant astrocytomas. | Core evidence 20090101 |
| New therapies for recurrent glioblastomas. | F1000 medicine reports 20090101 |
| Recent advances in managing triple-negative breast cancers. | F1000 medicine reports 20090101 |
| Evolving role of cetuximab in the treatment of colorectal cancer. | Cancer management and research 20090101 |
| Prevention of acute chemotherapy-induced nausea and vomiting: the role of palonosetron. | Cancer management and research 20090101 |
| Critical appraisal of temozolomide formulations in the treatment of primary brain tumors: patient considerations. | Cancer management and research 20090101 |
| Recent advances in the use of opioids for cancer pain. | Journal of pain research 20090101 |
| Direct effects of CPT-11 and SN38 on ovarian granulosa cells. | Molecular medicine reports 20090101 |
| Developments in treating metastatic colorectal cancer: Recent international reports from ASCO 2007 and 2008. | Clinical and experimental gastroenterology 20090101 |
| Recent advances in the management of carcinoma of the rectum. | Clinical and experimental gastroenterology 20090101 |
| Oxaliplatin: pre-clinical perspectives on the mechanisms of action, response and resistance. | Ecancermedicalscience 20090101 |
| Pharmacogenetics: implementing personalized medicine. | Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases 20090101 |
| Intra-arterial hepatic chemotherapy for unresectable colorectal liver metastases: a review of medical devices complications in 3172 patients. | Medical devices (Auckland, N.Z.) 20090101 |
| Radiofrequency ablation for hepatic metastasis from gastric adenocarcinoma. | Yonsei medical journal 20081231 |
| Semi-synthesis and biological activity of gamma-lactones analogs of camptothecin. | Bioorganic & medicinal chemistry letters 20081215 |
| Induction of Noxa sensitizes human colorectal cancer cells expressing Mcl-1 to the small-molecule Bcl-2/Bcl-xL inhibitor, ABT-737. | Clinical cancer research : an official journal of the American Association for Cancer Research 20081215 |
| Five-year data and prognostic factor analysis of oxaliplatin and irinotecan combinations for advanced colorectal cancer: N9741. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081210 |
| Emerging ethnic differences in lung cancer therapy. | British journal of cancer 20081202 |
| Antiproliferative activity of PEP005, a novel ingenol angelate that modulates PKC functions, alone and in combination with cytotoxic agents in human colon cancer cells. | British journal of cancer 20081202 |
| A heavily pretreated patient with recurrent clear cell adenocarcinoma of the ovary in whom carcinomatous peritonitis was controlled successfully by salvage therapy with gemcitabine. | Archives of gynecology and obstetrics 20081201 |
| A phase II study of irinotecan and docetaxel combination chemotherapy for patients with previously treated metastatic or recurrent advanced gastric cancer. | Cancer chemotherapy and pharmacology 20081201 |
| Recombinant human insulin-like growth factor-binding protein 3 inhibits tumor growth and targets the Akt pathway in lung and colon cancer models. | Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20081201 |
| Irinotecan in the treatment of elderly patients with advanced colorectal cancer. | Critical reviews in oncology/hematology 20081201 |
| Faecal microflora and beta-glucuronidase expression are altered in an irinotecan-induced diarrhea model in rats. | Cancer biology & therapy 20081201 |
| Genetic testing for UGT1A1*28 and *6 in Japanese patients who receive irinotecan chemotherapy. | Annals of oncology : official journal of the European Society for Medical Oncology 20081201 |
| A case report of glomerulopathy-associated podocytic infolding in a patient with tumor lysis syndrome. | Clinical and experimental nephrology 20081201 |
| Irinotecan plus cisplatin therapy and S-1 plus cisplatin therapy for advanced or recurrent gastric cancer in a single institution. | Japanese journal of clinical oncology 20081201 |
| Polymeric micellar delivery systems in oncology. | Japanese journal of clinical oncology 20081201 |
| What is the place of bevacizumab and irinotecan in the treatment of glioblastoma and other malignant gliomas? | Current opinion in neurology 20081201 |
| Exploring multi-targeting strategies for the treatment of gliomas. | Current opinion in investigational drugs (London, England : 2000) 20081201 |
| Emerging drugs for colorectal cancer. | Expert opinion on emerging drugs 20081201 |
| Pharmacogenomics of tamoxifen and irinotecan therapies. | Clinics in laboratory medicine 20081201 |
| Emerging antiangiogenic treatments for gliomas - efficacy and safety issues. | Current opinion in neurology 20081201 |
| Understanding the predictive role of K-ras for epidermal growth factor receptor-targeted therapies in colorectal cancer. | Clinical colorectal cancer 20081201 |
| Updated options for liver-limited metastatic colorectal cancer. | Clinical colorectal cancer 20081201 |
| In vitro-chemosensitivity test using the collagen gel droplet embedded culture drug test (CD-DST) for malignant pleural mesothelioma: possibility of clinical application. | Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia 20081201 |
| Bone marrow microenvironment and tumor progression. | Cancer microenvironment : official journal of the International Cancer Microenvironment Society 20081201 |
| A dialogue between the hypoxia-inducible factor and the tumor microenvironment. | Cancer microenvironment : official journal of the International Cancer Microenvironment Society 20081201 |
| Targeting colorectal cancer with anti-epidermal growth factor receptor antibodies: focus on panitumumab. | Therapeutics and clinical risk management 20081201 |
| Colorectal cancer patients with liver metastases and severe hyperbilirubinemia: A consecutive series that explores the benefits and risks of chemotherapy. | Therapeutics and clinical risk management 20081201 |
| Takotsubo cardiomyopathy in two men receiving bevacizumab for metastatic cancer. | Therapeutics and clinical risk management 20081201 |
| Alternative splicing and tumor progression. | Current genomics 20081201 |
| Novel microtubule-targeting agents - the epothilones. | Biologics : targets & therapy 20081201 |
| First-line therapeutic strategies in metastatic colorectal cancer. | Oncology (Williston Park, N.Y.) 20081130 |
| Cetuximab plus irinotecan in heavily pretreated metastatic colorectal cancer progressing on irinotecan: MABEL Study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081120 |
| Pathologic response to preoperative chemotherapy: a new outcome end point after resection of hepatic colorectal metastases. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081120 |
| Phase 2 study of gemcitabine and irinotecan in metastatic breast cancer with correlatives to determine topoisomerase I localization as a predictor of response. | Cancer 20081115 |
| Efficient one-cycle affinity selection of binding proteins or peptides specific for a small-molecule using a T7 phage display pool. | Bioorganic & medicinal chemistry 20081115 |
| A liquid chromatography/electrospray ionization mass spectrometry (LC-MS/MS) assay for the determination of irinotecan (CPT-11) and its two major metabolites in human liver microsomal incubations and human plasma samples. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081115 |
| Irinophore C, a novel nanoformulation of irinotecan, alters tumor vascular function and enhances the distribution of 5-fluorouracil and doxorubicin. | Clinical cancer research : an official journal of the American Association for Cancer Research 20081115 |
| G-quadruplex ligand RHPS4 potentiates the antitumor activity of camptothecins in preclinical models of solid tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20081115 |
| Antitumor effect of SN-38-releasing polymeric micelles, NK012, on spontaneous peritoneal metastases from orthotopic gastric cancer in mice compared with irinotecan. | Cancer research 20081115 |
| Antibody conjugates of 7-ethyl-10-hydroxycamptothecin (SN-38) for targeted cancer chemotherapy. | Journal of medicinal chemistry 20081113 |
| Gene expression profiling of liver metastases from colorectal cancer as potential basis for treatment choice. | British journal of cancer 20081104 |
| Targeting ErbB2 and ErbB3 with a bispecific single-chain Fv enhances targeting selectivity and induces a therapeutic effect in vitro. | British journal of cancer 20081104 |
| Microsatellite instability due to hMLH1 deficiency is associated with increased cytotoxicity to irinotecan in human colorectal cancer cell lines. | British journal of cancer 20081104 |
| Safety and pharmacokinetics of motesanib in combination with gemcitabine for the treatment of patients with solid tumours. | British journal of cancer 20081104 |
| Second-line chemotherapy for patients with advanced gastric cancer: who may benefit? | British journal of cancer 20081104 |
| Safety and outcome of definitive chemoradiotherapy in elderly patients with oesophageal cancer. | British journal of cancer 20081104 |
| Salvage treatment with topotecan in patients with irinotecan-refractory small cell lung cancer. | Cancer chemotherapy and pharmacology 20081101 |
| Use of the folinic acid/5-fluorouracil/irinotecan (FOLFIRI 1) regimen in elderly patients as a first-line treatment for metastatic colorectal cancer: a Phase II study. | Cancer chemotherapy and pharmacology 20081101 |
| Pharmacokinetics of irinotecan and its metabolites in pediatric cancer patients: a report from the children's oncology group. | Cancer chemotherapy and pharmacology 20081101 |
| First synthesis of novel spin-labeled derivatives of camptothecin as potential antineoplastic agents. | European journal of medicinal chemistry 20081101 |
| Cisplatin plus weekly CPT-11/docetaxel in advanced esophagogastric cancer: a phase I study with pharmacogenetic assessment of XPD, XRCC3 and UGT1A1 polymorphisms. | Cancer chemotherapy and pharmacology 20081101 |
| Clinical and pharmacogenetic factors associated with irinotecan toxicity. | Cancer treatment reviews 20081101 |
| A phase II study of thalidomide and irinotecan for treatment of glioblastoma multiforme. | Journal of neuro-oncology 20081101 |
| A phase II randomized multicenter trial of gefitinib plus FOLFIRI and FOLFIRI alone in patients with metastatic colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20081101 |
| Overexpression of carboxylesterase-2 results in enhanced efficacy of topoisomerase I inhibitor, irinotecan (CPT-11), for multiple myeloma. | Cancer science 20081101 |
| A personalized approach to cancer treatment: how biomarkers can help. | Clinical chemistry 20081101 |
| A phase II study of irinotecan in children with relapsed or refractory neuroblastoma: a European cooperation of the Société Française d'Oncologie Pédiatrique (SFOP) and the United Kingdom Children Cancer Study Group (UKCCSG). | European journal of cancer (Oxford, England : 1990) 20081101 |
| Chemotherapy for gastric cancer that recurs after adjuvant chemotherapy with S-1. | Japanese journal of clinical oncology 20081101 |
| Rapid allelic discrimination by TaqMan PCR for the detection of the Gilbert's syndrome marker UGT1A1*28. | The Journal of molecular diagnostics : JMD 20081101 |
| Multicenter Phase II study of cetuximab plus irinotecan in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin and fluoropyrimidines. | Japanese journal of clinical oncology 20081101 |
| Antiangiogenic therapy in malignant gliomas. | Current opinion in oncology 20081101 |
| Novel bone cancer drugs: investigational agents and control paradigms for primary bone sarcomas (Ewing's sarcoma and osteosarcoma). | Expert opinion on investigational drugs 20081101 |
| Interspecies scaling of a camptothecin analogue: human predictions for intravenous topotecan using animal data. | Xenobiotica; the fate of foreign compounds in biological systems 20081101 |
| Oncoprotein Bcl-2 and microsatellite instability are associated with disease-free survival and treatment response in colorectal cancer. | Oncology reports 20081101 |
| Effects of breast cancer resistance protein inhibitors and pharmaceutical excipients on decreasing gastrointestinal toxicity of camptothecin analogs. | Acta pharmacologica Sinica 20081101 |
| Bevacizumab plus irinotecan in recurrent WHO grade 3 malignant gliomas. | Clinical cancer research : an official journal of the American Association for Cancer Research 20081101 |
| Association of ATP-binding cassette, sub-family C, number 2 (ABCC2) genotype with pharmacokinetics of irinotecan in Japanese patients with metastatic colorectal cancer treated with irinotecan plus infusional 5-fluorouracil/leucovorin (FOLFIRI). | Biological & pharmaceutical bulletin 20081101 |
| Low-dose protracted irinotecan as a palliative chemotherapy for advanced neuroblastoma. | Journal of pediatric hematology/oncology 20081101 |
| Variation in the cost of medications for the treatment of colorectal cancer. | The American journal of managed care 20081101 |
| [A case of recurrent gastroesophageal junction adenocarcinoma successfully treated with radiation plus chemotherapy (5-FU+CDDP, S-1, Paclitaxel, CPT-11) for long-term survival with good QOL]. | Gan to kagaku ryoho. Cancer & chemotherapy 20081101 |
| [Marked response to combination chemotherapy using S-1, CPT-11 for lymph node metastasis of gastric cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20081101 |
| [A case of metastatic lung and liver tumors from rectal cancer treated with oral UFT and CPT-11 by hepatic arterial infusion followed by FOLFOX and FOLFIRI]. | Gan to kagaku ryoho. Cancer & chemotherapy 20081101 |
| Race does not explain genetic heterogeneity in pharmacogenomic pathways. | Pharmacogenomics 20081101 |
| Role of combined-modality therapy in the management of locally advanced rectal cancer. | Clinical colorectal cancer 20081101 |
| Results of a phase II trial of cetuximab plus capecitabine/irinotecan as first-line therapy for patients with advanced and/or metastatic colorectal cancer. | Clinical colorectal cancer 20081101 |
| [New perspectives in predicting response to chemotherapy in colorectal cancer]. | Gastroenterologia y hepatologia 20081101 |
| [Third-line treatment of intermittent hepatic arterial infusion for unresectable liver metastases from colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20081101 |
| [A case of unresectable advanced gastric cancer successfully treated with continuous S-1 + CPT-11 chemotherapy accompanied by dose reduction against grade 4 hematological adverse event]. | Gan to kagaku ryoho. Cancer & chemotherapy 20081101 |
| [A case of long-term disease free survival after three surgical resections for local recurrence and lung metastases from rectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20081101 |
| [A case of advanced sigmoid colon cancer performed resection of liver metastases after long-term control by S-1 and CPT-11 combination chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20081101 |
| [A case of ovarian cancer in which a remarkable effect was seen with intrathoracic administration of CDDP and CPT-11]. | Gan to kagaku ryoho. Cancer & chemotherapy 20081101 |
| [Phase I study of combination therapy with peptide vaccine and anti-cancer drug for colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20081101 |
| [The validity of full administration of 5-fluorouracil, irinotecan, and oxaliplatin to unresectable or recurrent colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20081101 |
| Severe acneiform eruption induced by cetuximab (Erbitux). | Yonsei medical journal 20081031 |
| Bcl-2 expression significantly correlates with thymidylate synthase expression in colorectal cancer patients. | World journal of gastroenterology 20081028 |
| GSTP1 Ile105Val polymorphism correlates with progression-free survival in MCRC patients treated with or without irinotecan: a study of the Dutch Colorectal Cancer Group. | British journal of cancer 20081021 |
| Pharmacokinetic and pharmacogenetic determinants of the activity and toxicity of irinotecan in metastatic colorectal cancer patients. | British journal of cancer 20081021 |
| Cost-effectiveness of adjuvant chemotherapy with uracil-tegafur for curatively resected stage III rectal cancer. | British journal of cancer 20081021 |
| C-Fos expression is a molecular predictor of progression and survival in epithelial ovarian carcinoma. | British journal of cancer 20081021 |
| Clinical determinants of response to irinotecan-based therapy derived from cell line models. | Clinical cancer research : an official journal of the American Association for Cancer Research 20081015 |
| A phase 1 dose-escalation study of irinotecan in combination with 17-allylamino-17-demethoxygeldanamycin in patients with solid tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20081015 |
| Urgent need for a new staging system in advanced colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081010 |
| Management and survival trends in advanced colorectal cancer. | Clinical oncology (Royal College of Radiologists (Great Britain)) 20081001 |
| Capecitabine plus oxaliplatin (XELOX) versus 5-fluorouracil/folinic acid plus oxaliplatin (FOLFOX-4) as second-line therapy in metastatic colorectal cancer: a randomized phase III noninferiority study. | Annals of oncology : official journal of the European Society for Medical Oncology 20081001 |
| Randomized phase 2 study of subcutaneous amifostine versus epoetin-alpha given 3 times weekly during concurrent chemotherapy and hyperfractionated radiotherapy for limited-disease small cell lung cancer. | Cancer 20081001 |
| Novel human antibody therapeutics: the age of the Umabs. | Biotechnology journal 20081001 |
| Induction of P-glycoprotein expression and function in human intestinal epithelial cells (T84). | Biochemical pharmacology 20081001 |
| Irinotecan and uridine diphosphate glucuronosyltransferase 1A1 pharmacogenetics: to test or not to test, that is the question. | Cancer 20081001 |
| Bevacizumab: a treatment option for recurrent glioblastoma multiforme. | The Annals of pharmacotherapy 20081001 |
| Comparison of proportional and differential odds models for mixed-effects analysis of categorical data. | Journal of pharmacokinetics and pharmacodynamics 20081001 |
| Metabolism of irinotecan and its active metabolite SN-38 by intestinal microflora in rats. | Oncology reports 20081001 |
| New lessons from 'old' chemotherapy in colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081001 |
| Oxaliplatin plus irinotecan compared with irinotecan alone as second-line treatment after single-agent fluoropyrimidine therapy for metastatic colorectal carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081001 |
| Chemotherapy for colorectal cancer liver metastases. | The oncologist 20081001 |
| A phase I trial of irinotecan alternating with epirubicin in patients with advanced malignancies. | American journal of clinical oncology 20081001 |
| Impact of baseline sum of longest diameter in target lesions by RECIST on survival of patients with metastatic colorectal cancer. | Japanese journal of clinical oncology 20081001 |
| Bone marrow and tumor cell colony-forming units and human tumor xenograft efficacy of noncamptothecin and camptothecin topoisomerase I inhibitors. | Molecular cancer therapeutics 20081001 |
| An update on biochemotherapy of advanced gastric and gastroesophageal adenocarcinoma. | Journal of the National Comprehensive Cancer Network : JNCCN 20081001 |
| [Phase I study of CPT-11 and continuous 5-FU / l-leucovorin combination therapy(modified AIO regimen)in patients with metastatic colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20081001 |
| [A fatal case of small cell type undifferentiated carcinoma of the esophagus with sudden diarrhea and bloody discharge by CPT-11]. | Gan to kagaku ryoho. Cancer & chemotherapy 20081001 |
| [A case of successful control for primary duodenal cancer with combined CPT-11, CDDP and DOC chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20081001 |
| Complete remission of unresectable colon cancer after preoperative chemotherapy selected by adenosine triphosphate-based chemotherapy response assay. | Journal of Korean medical science 20081001 |
| [Stage IV NSCLC. Place of chemotherapy]. | Revue des maladies respiratoires 20081001 |
| In vivo chemotherapeutic profile of human gallbladder small cell carcinoma. | Biomedical research (Tokyo, Japan) 20081001 |
| [Is it possible to individualize prescription of medical treatment in colorectal cancer? The clinician point of view]. | Bulletin du cancer 20081001 |
| [The biological point of view on pharmacogenetics of anticancer agents in colorectal cancer]. | Bulletin du cancer 20081001 |
| The confused cancer patient: a case of 5-fluorouracil-induced encephalopathy. | Current oncology (Toronto, Ont.) 20081001 |
| Bimonthly chemotherapy with oxaliplatin, irinotecan, infusional 5-fluorouracil/folinic acid in patients with metastatic colorectal cancer pretreated with irinotecan- or oxaliplatin-based chemotherapy. | Journal of chemotherapy (Florence, Italy) 20081001 |
| Docetaxel in the treatment of squamous cell carcinoma of the head and neck. | Therapeutics and clinical risk management 20081001 |
| Multi-targeted approach in the treatment of thyroid cancer. | Therapeutics and clinical risk management 20081001 |
| Review of docetaxel in the treatment of gastric cancer. | Therapeutics and clinical risk management 20081001 |
| Phase II study of short-time oxaliplatin, capecitabine and epirubicin (EXE) as first-line therapy in patients with non-resectable gastric cancer. | British journal of cancer 20080916 |
| Development and validation of reversed phase liquid chromatographic method utilizing ultraviolet detection for quantification of irinotecan (CPT-11) and its active metabolite, SN-38, in rat plasma and bile samples: application to pharmacokinetic studies. | Talanta 20080915 |
| 11-Substituted 2,3-dimethoxy-8,9-methylenedioxybenzo[i]phenanthridine derivatives as novel topoisomerase I-targeting agents. | Bioorganic & medicinal chemistry 20080915 |
| Irinotecan plus carboplatin versus oral etoposide plus carboplatin in extensive small-cell lung cancer: a randomized phase III trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080910 |
| Will histone deacetylase inhibitors require combination with other agents to fulfil their therapeutic potential? | British journal of cancer 20080902 |
| Liver-only metastatic colorectal cancer patients and thymidylate synthase polymorphisms for predicting response to 5-fluorouracil-based chemotherapy. | British journal of cancer 20080902 |
| A phase II study of UFT with leucovorin administered as a twice daily schedule in the treatment of patients with metastatic colorectal cancer. | British journal of cancer 20080902 |
| Cetuximab efficacy and safety in a retrospective cohort of elderly patients with heavily pretreated metastatic colorectal cancer. | Critical reviews in oncology/hematology 20080901 |
| Pharmacogenetic pathway analysis of irinotecan. | Clinical pharmacology and therapeutics 20080901 |
| CPT-11 for recurrent temozolomide-refractory 1p19q co-deleted anaplastic oligodendroglioma. | Journal of neuro-oncology 20080901 |
| Overcoming S-phase checkpoint-mediated resistance: sequence-dependent synergy of gemcitabine and 7-ethyl-10-hydroxycamptothecin (SN-38) in human carcinoma cell lines. | Molecular pharmacology 20080901 |
| Significant antitumor activity of cationic multilamellar liposomes containing human interferon-beta gene in combination with 5-fluorouracil against human renal cell carcinoma. | International journal of oncology 20080901 |
| Efficacy of the combined use of bevacizumab and irinotecan as a postoperative adjuvant chemotherapy in colon carcinoma. | Oncology reports 20080901 |
| Synergism of CPT-11 and Apo2L/TRAIL against two differentially sensitive human colon tumor xenografts. | Oncology 20080901 |
| Modifications of human carboxylesterase for improved prodrug activation. | Expert opinion on drug metabolism & toxicology 20080901 |
| Randomized phase II study of maintenance irinotecan therapy versus observation following induction chemotherapy with irinotecan and cisplatin in extensive disease small cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20080901 |
| Anti-EGFR monoclonal antibodies in metastatic colorectal cancer: time for an individualized approach? | Expert review of anticancer therapy 20080901 |
| Thymidine selectively enhances growth suppressive effects of camptothecin/irinotecan in MSI+ cells and tumors containing a mutation of MRE11. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080901 |
| Irinotecan combined with 5-fluorouracil and leucovorin as second-line chemotherapy for metastatic or relapsed gastric cancer. | Japanese journal of clinical oncology 20080901 |
| Health-related quality of life impact of bevacizumab when combined with irinotecan, 5-fluorouracil, and leucovorin or 5-fluorouracil and leucovorin for metastatic colorectal cancer. | The oncologist 20080901 |
| Therapeutic application of noncytotoxic molecular targeted therapy in gliomas: growth factor receptors and angiogenesis inhibitors. | The oncologist 20080901 |
| Novel opportunities for thymidylate metabolism as a therapeutic target. | Molecular cancer therapeutics 20080901 |
| Update on novel strategies to optimize cetuximab therapy in patients with metastatic colorectal cancer. | Clinical colorectal cancer 20080901 |
| Sequential versus combination therapy in the treatment of patients with advanced colorectal cancer. | Clinical colorectal cancer 20080901 |
| An autopsy case of acute pulmonary toxicity related to irinotecan. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20080901 |
| [Chemotherapy for metastatic colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080901 |
| [Efficacy of low-dose CDDP and CPT-11 for patients with intestinal type of gastric adenocarcinoma]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080901 |
| [A case of advanced gastric cancer with pulmonary carcinomatous lymphangitis and paraaortic lymph node metastases responding to combination chemotherapy of S-1 and irinotecan(CPT-11)]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080901 |
| [Three cases with liver metastasis from gastric or colon cancer successfully treated with S-1 combined with CPT- 11]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080901 |
| [Chemotherapy for human gastric cancer: a review]. | Revue medicale de Liege 20080901 |
| Colon-targeted delivery of live bacterial cell biotherapeutics including microencapsulated live bacterial cells. | Biologics : targets & therapy 20080901 |
| Targeted therapies in the management of renal cell carcinoma: role of bevacizumab. | Biologics : targets & therapy 20080901 |
| The comparison of cytotoxicity of the anticancer drugs doxorubicin and ellipticine to human neuroblastoma cells. | Interdisciplinary toxicology 20080901 |
| PEGylated nanographene oxide for delivery of water-insoluble cancer drugs. | Journal of the American Chemical Society 20080820 |
| Alternating irinotecan with oxaliplatin combined with UFT plus leucovorin (SCOUT) in metastatic colorectal cancer. | British journal of cancer 20080819 |
| Association of p53 codon 72 polymorphism and MDM2 SNP309 with clinical outcome of advanced nonsmall cell lung cancer. | Cancer 20080815 |
| Pre-clinical evidence for altered absorption and biliary excretion of irinotecan (CPT-11) in combination with quercetin: possible contribution of P-glycoprotein. | Life sciences 20080815 |
| Syntheses and biological evaluation of topoisomerase I-targeting agents related to 11-[2-(N,N-dimethylamino)ethyl]-2,3-dimethoxy-8,9-methylenedioxy-11H-isoquino[4,3-c]cinnolin-12-one (ARC-31). | Bioorganic & medicinal chemistry 20080815 |
| Enhanced antitumor therapy by inhibition of p21waf1 in human malignant mesothelioma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080815 |
| Phase II study of combination therapy with S-1 and irinotecan for advanced non-small cell lung cancer: west Japan thoracic oncology group 3505. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080815 |
| Food-drug interaction of (-)-epigallocatechin-3-gallate on the pharmacokinetics of irinotecan and the metabolite SN-38. | Chemico-biological interactions 20080811 |
| Clinical interest of KRAS mutation detection in blood for anti-EGFR therapies in metastatic colorectal cancer. | British journal of cancer 20080805 |
| Biweekly cetuximab and irinotecan in advanced colorectal cancer patients progressing after at least one previous line of chemotherapy: results of a phase II single institution trial. | British journal of cancer 20080805 |
| Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFIRI chemotherapy. | The pharmacogenomics journal 20080801 |
| Phase II study of nedaplatin and irinotecan followed by gefitinib for elderly patients with unresectable non-small cell lung cancer. | Cancer chemotherapy and pharmacology 20080801 |
| A Phase I and pharmacokinetic study of selenomethionine in combination with a fixed dose of irinotecan in solid tumors. | Cancer chemotherapy and pharmacology 20080801 |
| Impact of CYP3A4 haplotypes on irinotecan pharmacokinetics in Japanese cancer patients. | Cancer chemotherapy and pharmacology 20080801 |
| Combination chemotherapy with irinotecan and cisplatin in elderly patients (>or= 65 years) with extensive-disease small-cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20080801 |
| Renal function as a predictor of irinotecan-induced neutropenia. | Clinical pharmacology and therapeutics 20080801 |
| Gastrointestinal ulceration as a possible side effect of bevacizumab which may herald perforation. | Investigational new drugs 20080801 |
| Phase II study of sequentially administered low-dose mitomycin-C (MMC) and irinotecan (CPT-11) in women with metastatic breast cancer (MBC). | Annals of oncology : official journal of the European Society for Medical Oncology 20080801 |
| Irinotecan and bevacizumab in progressive primary brain tumors, an evaluation of efficacy and safety. | Journal of neuro-oncology 20080801 |
| Transcriptional repression of O6-methylguanine DNA methyltransferase gene rendering cells hypersensitive to N,N'-bis(2-chloroethyl)-N-nitrosurea in camptothecin-resistant cells. | Molecular pharmacology 20080801 |
| Predictive factors for chemotherapy-related toxic effects in patients with colorectal cancer. | Nature clinical practice. Oncology 20080801 |
| Randomized phase III study comparing irinotecan combined with 5-fluorouracil and folinic acid to cisplatin combined with 5-fluorouracil in chemotherapy naive patients with advanced adenocarcinoma of the stomach or esophagogastric junction. | Annals of oncology : official journal of the European Society for Medical Oncology 20080801 |
| Scheduled administration of low dose irinotecan before gemcitabine in the second line therapy of non-small cell lung cancer: a phase II study. | Anti-cancer drugs 20080801 |
| Colorectal tumor cells treated with 5-FU, oxaliplatin, irinotecan, and cetuximab exhibit changes in 18F-FDG incorporation corresponding to hexokinase activity and glucose transport. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080801 |
| A randomised phase III trial of adjuvant radio-chemotherapy comparing Irinotecan, 5FU and Leucovorin to 5FU and Leucovorin in patients with rectal cancer: a Hellenic Cooperative Oncology Group Study. | European journal of cancer (Oxford, England : 1990) 20080801 |
| Hypoxia-specific drug tirapazamine does not abrogate hypoxic tumor cells in combination therapy with irinotecan and methylselenocysteine in well-differentiated human head and neck squamous cell carcinoma a253 xenografts. | Neoplasia (New York, N.Y.) 20080801 |
| Bevacizumab and irinotecan therapy in glioblastoma multiforme: a series of 13 cases. | Journal of neurosurgery 20080801 |
| Combination chemotherapy and ALVAC-CEA/B7.1 vaccine in patients with metastatic colorectal cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080801 |
| Pharmacogenetics in colorectal cancer: a systematic review. | Pharmacogenomics 20080801 |
| Celecoxib upregulates multidrug resistance proteins in colon cancer: lack of synergy with standard chemotherapy. | Current cancer drug targets 20080801 |
| Disparities in the use of chemotherapy and monoclonal antibody therapy for elderly advanced colorectal cancer patients in the community oncology setting. | The oncologist 20080801 |
| Oxaliplatin-based chemotherapy in the management of colorectal cancer. | Expert review of anticancer therapy 20080801 |
| [Docetaxel (TXT) and irinotecan (CPT-11) as a second-line chemotherapy for platinum-pretreated squamous cell carcinoma of the head and neck]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080801 |
| Phase II study of paclitaxel, cisplatin, and 5-fluorouracil combination chemotherapy in patients with advanced gastric cancer. | Journal of Korean medical science 20080801 |
| Cetuximab treatment in a patient with metastatic colorectal cancer and psoriasis. | Current oncology (Toronto, Ont.) 20080801 |
| Effect of D256N and Y483D on propofol glucuronidation by human uridine 5'-diphosphate glucuronosyltransferase (UGT1A9). | Basic & clinical pharmacology & toxicology 20080801 |
| Role of pharmacogenomics in drug discovery and development. | Indian journal of pharmacology 20080801 |
| A ubiquitin-proteasome pathway for the repair of topoisomerase I-DNA covalent complexes. | The Journal of biological chemistry 20080725 |
| Inequity in colorectal cancer treatment and outcomes: a population-based study. | British journal of cancer 20080722 |
| UGT1A1*28 genotype and irinotecan dosage in patients with metastatic colorectal cancer: a Dutch Colorectal Cancer Group study. | British journal of cancer 20080722 |
| Randomized phase 2 study of irinotecan plus cisplatin versus gemcitabine plus vinorelbine as first-line chemotherapy with second-line crossover in patients with advanced nonsmall cell lung cancer. | Cancer 20080715 |
| EGFR-targeting drugs in combination with cytotoxic agents: from bench to bedside, a contrasted reality. | British journal of cancer 20080708 |
| Primary resistance to cetuximab therapy in EGFR FISH-positive colorectal cancer patients. | British journal of cancer 20080708 |
| Combined effects of bevacizumab with erlotinib and irradiation: a preclinical study on a head and neck cancer orthotopic model. | British journal of cancer 20080708 |
| [Pharmacogenetics in oncology]. | Medicina clinica 20080705 |
| Multicenter phase-II trial of irinotecan plus oxaliplatin [IROX regimen] in patients with poor-prognosis cancer of unknown primary: a hellenic cooperative oncology group study. | Cancer chemotherapy and pharmacology 20080701 |
| Tritherapy with fluorouracil/leucovorin, irinotecan and oxaliplatin (FOLFIRINOX): a phase II study in colorectal cancer patients with non-resectable liver metastases. | Cancer chemotherapy and pharmacology 20080701 |
| Irinotecan plus cisplatin and dexamethasone (ICD) combination chemotherapy for patients with diffuse large B-cell lymphoma previously treated with Rituximab plus CHOP. | Cancer chemotherapy and pharmacology 20080701 |
| Vaccination of colorectal cancer patients with TroVax given alongside chemotherapy (5-fluorouracil, leukovorin and irinotecan) is safe and induces potent immune responses. | Cancer immunology, immunotherapy : CII 20080701 |
| Effect of preoperative chemotherapy on liver resection for colorectal liver metastases. | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20080701 |
| Irinotecan and cisplatin with concurrent thoracic radiotherapy in a once-every-three-weeks schedule in patients with limited-disease small-cell lung cancer: a phase I study. | Lung cancer (Amsterdam, Netherlands) 20080701 |
| Activated charcoal to prevent irinotecan-induced diarrhea in children. | Pediatric blood & cancer 20080701 |
| Intra and inter-molecular interactions dictate the aggregation state of irinotecan co-encapsulated with floxuridine inside liposomes. | Pharmaceutical research 20080701 |
| A phase II multicentre study of irinotecan (CPT 11) in combination with cisplatin (CDDP) in metastatic or locally advanced penile carcinoma (EORTC PROTOCOL 30992). | Annals of oncology : official journal of the European Society for Medical Oncology 20080701 |
| Potential oral delivery of 7-ethyl-10-hydroxy-camptothecin (SN-38) using poly(amidoamine) dendrimers. | Pharmaceutical research 20080701 |
| Isolated hepatic perfusion with 200 mg melphalan for advanced noncolorectal liver metastases. | Annals of surgical oncology 20080701 |
| Phase II trial of irinotecan plus cisplatin in patients with recurrent or metastatic squamous carcinoma of the head and neck. | Cancer 20080701 |
| Family 1 uridine-5'-diphosphate glucuronosyltransferases (UGT1A): from Gilbert's syndrome to genetic organization and variability. | Archives of toxicology 20080701 |
| Oxaliplatin activity in selected and unselected human ovarian and colorectal cancer cell lines. | Biochemical pharmacology 20080701 |
| In vitro and in vivo anti-tumoral activities of imidazo[1,2-a]quinoxaline, imidazo[1,5-a]quinoxaline, and pyrazolo[1,5-a]quinoxaline derivatives. | Bioorganic & medicinal chemistry 20080701 |
| Serum levels of NFkappaB and pro-inflammatory cytokines following administration of mucotoxic drugs. | Cancer biology & therapy 20080701 |
| Metastatic rectal cancer responding to third-line therapy employing bevacizumab after failure of oxaliplatin and irinotecan: case report. | Japanese journal of clinical oncology 20080701 |
| Glioblastoma multiforme. | Current treatment options in neurology 20080701 |
| Early magnesium reduction in advanced colorectal cancer patients treated with cetuximab plus irinotecan as predictive factor of efficacy and outcome. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080701 |
| Bevacizumab plus irinotecan-, fluorouracil-, and leucovorin-based chemotherapy with concomitant HAART in an HIV-positive patient with metastatic colorectal cancer. | Onkologie 20080701 |
| A case of relapsing secondary bladder adenocarcinoma after right colonic cancer. | Nature clinical practice. Urology 20080701 |
| Is there an optimal chemotherapy regimen for the treatment of advanced gastric cancer that will provide a platform for the introduction of new biological agents? | The oncologist 20080701 |
| [Role of UGT1A1*28 and UGT1A1*6 for irinotecan-induced adverse drug reaction]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080701 |
| [Long survival of advanced gastric cancer patient after total gastrectomy and postoperative treatment with S-1 despite S-1+CDDP+CPT-11 causing perforation]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080701 |
| [A case of Stage IV gastric cancer with liver and peritoneal metastases responding completely to tailored S-1/CPT- 11 combination therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080701 |
| [A case of brain metastasis from advanced ovarian clear-cell carcinoma during maintenance chemotherapy with irinotecan+cisplatin]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080701 |
| Chemosensitizing effects of sphingosine kinase-1 inhibition in prostate cancer cell and animal models. | Molecular cancer therapeutics 20080701 |
| Preclinical profile of antitumor activity of a novel hydrophilic camptothecin, ST1968. | Molecular cancer therapeutics 20080701 |
| Regional chemotherapy for liver-limited metastatic colorectal cancer. | Clinical colorectal cancer 20080701 |
| A phase II study of cetuximab/irinotecan in patients with heavily pretreated metastatic colorectal cancer: predictive value of early specific toxicities. | Clinical colorectal cancer 20080701 |
| [Case report of malignant sertoli cell tumor]. | Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20080701 |
| Preferences of patients with advanced colorectal cancer for treatment with oral or intravenous chemotherapy. | The patient 20080701 |
| Bcl-x(L) and Myeloid cell leukaemia-1 contribute to apoptosis resistance of colorectal cancer cells. | World journal of gastroenterology 20080628 |
| Thymidylate synthase, thymidine phosphorylase and orotate phosphoribosyl transferase levels as predictive factors of chemotherapy in oral squamous cell carcinoma. | Acta histochemica et cytochemica 20080627 |
| Tumour-stroma interactions in colorectal cancer: converging on beta-catenin activation and cancer stemness. | British journal of cancer 20080617 |
| Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). | Journal of medicinal chemistry 20080612 |
| Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors. | Journal of medicinal chemistry 20080612 |
| Influence of UGT1A9 intronic I399C>T polymorphism on SN-38 glucuronidation in Asian cancer patients. | The pharmacogenomics journal 20080601 |
| Characterisation of mucosal changes in the alimentary tract following administration of irinotecan: implications for the pathobiology of mucositis. | Cancer chemotherapy and pharmacology 20080601 |
| Phase I study of vinorelbine and irinotecan in previously untreated patients with advanced non-small cell lung cancer. | Cancer chemotherapy and pharmacology 20080601 |
| Hepatic complications following preoperative chemotherapy with oxaliplatin or irinotecan for hepatic colorectal metastases. | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20080601 |
| Effects of drug efflux proteins and topoisomerase I mutations on the camptothecin analogue gimatecan. | Investigational new drugs 20080601 |
| BCRP/ABCG2 in the placenta: expression, function and regulation. | Pharmaceutical research 20080601 |
| Palliative chemotherapy in elderly patients with common metastatic malignancies: A Hellenic Cooperative Oncology Group registry analysis of management, outcome and clinical benefit predictors. | Critical reviews in oncology/hematology 20080601 |
| Biweekly cetuximab and irinotecan as third-line therapy in patients with advanced colorectal cancer after failure to irinotecan, oxaliplatin and 5-fluorouracil. | Annals of oncology : official journal of the European Society for Medical Oncology 20080601 |
| Chronomodulated capecitabine in combination with short-time oxaliplatin: a Nordic phase II study of second-line therapy in patients with metastatic colorectal cancer after failure to irinotecan and 5-flourouracil. | Annals of oncology : official journal of the European Society for Medical Oncology 20080601 |
| Advances in neoadjuvant therapy for colorectal cancer with liver metastases. | Cancer treatment reviews 20080601 |
| Altered expression of cell proliferation-related and interferon-stimulated genes in colon cancer cells resistant to SN38. | Cancer biology & therapy 20080601 |
| Vascular endothelial growth factor expression is closely related to irinotecan-mediated inhibition of tumor growth and angiogenesis in neuroblastoma xenografts. | Cancer science 20080601 |
| Capecitabine, irinotecan, oxaliplatin (CAPIRINOX) and concomitant irradiation in advanced rectal cancer: the Lyon R-02-01 phase I trial. | Clinical oncology (Royal College of Radiologists (Great Britain)) 20080601 |
| Determination of anticarcinogenic and rescue therapy drugs in urine by photoinduced spectrofluorimetry using multivariate calibration: comparison of several second-order methods. | Analytical and bioanalytical chemistry 20080601 |
| Enhanced distribution of NK012, a polymeric micelle-encapsulated SN-38, and sustained release of SN-38 within tumors can beat a hypovascular tumor. | Cancer science 20080601 |
| Phase I trial of neoadjuvant concurrent chemoradiotherapy with S-1 and weekly irinotecan in locally advanced rectal cancer. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20080601 |
| Intracellular accumulation and DNA damage persistence as determinants of human squamous cell carcinoma hypersensitivity to the novel camptothecin ST1968. | European journal of cancer (Oxford, England : 1990) 20080601 |
| Assessing the optimal duration of chemotherapy in patients with colorectal liver metastases. | Journal of surgical oncology 20080601 |
| CYP450 pharmacogenetics for personalizing cancer therapy. | Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20080601 |
| Anticancer effect of SN-38 on colon cancer cell lines with different metastatic potential. | Oncology reports 20080601 |
| Genomic analyses identify gene candidates for acquired irinotecan resistance in melanoma cells. | International journal of oncology 20080601 |
| Current and emerging therapies for metastatic colorectal cancer: applying research findings to clinical practice. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080601 |
| Epidermal growth factor receptor monoclonal antibodies for the treatment of metastatic colorectal cancer. | Pharmacotherapy 20080601 |
| Pharmacogenetic testing for uridine diphosphate glucuronosyltransferase 1A1 polymorphisms: are we there yet? | Pharmacotherapy 20080601 |
| Cutaneous adverse drug reactions during chemotherapy: consider non-antineoplastic drugs. | Contact dermatitis 20080601 |
| Predictive biomarkers of chemotherapy efficacy in colorectal cancer: results from the UK MRC FOCUS trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080601 |
| Pharmacogenetics of Gilbert's syndrome. | Pharmacogenomics 20080601 |
| Irinotecan plus cisplatin for therapy of small-cell carcinoma of the esophagus: report of 12 cases from single institution experience. | Japanese journal of clinical oncology 20080601 |
| An attempt to evaluate the effect of vitamin K3 using as an enhancer of anticancer agents. | Biological & pharmaceutical bulletin 20080601 |
| Phase I dose escalation study with irinotecan, capecitabine, epirubicin, and granulocyte colony-stimulating factor support for patients with solid malignancies. | American journal of clinical oncology 20080601 |
| Population-based phase I trial of irinotecan and epirubicin. | American journal of clinical oncology 20080601 |
| Chemotherapy for metastatic disease: review from JCOG trials. | International journal of clinical oncology 20080601 |
| ISG15 as a novel tumor biomarker for drug sensitivity. | Molecular cancer therapeutics 20080601 |
| [Progression in palliative chemotherapy for advanced colorectal cancer]. | Ai zheng = Aizheng = Chinese journal of cancer 20080601 |
| The cost burden of trastuzumab and bevacizumab therapy for solid tumours in Canada. | Current oncology (Toronto, Ont.) 20080601 |
| The role of cetuximab in pre-treated refractory patients with metastatic colorectal cancer: outcome study in clinical practice. | Journal of chemotherapy (Florence, Italy) 20080601 |
| Neoadjuvant chemoradiation for rectal cancer: is more better? | Oncology (Williston Park, N.Y.) 20080601 |
| [Prevention of irinotecan hydrochloride-induced diarrhea by oral administration of Lactobacillus casei strain Shirota in rats]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080601 |
| [CR obtained by CPT-11 and CDDP combination-therapy in a small-cell lung-cancer patient through effective pharmaceutical care]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080601 |
| [A case of interstitial pneumonia induced by S-1/irinotecan combination therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080601 |
| [A case of sigmoid colon cancer with metastases of para-aortic lymph nodes treated with curative resection after irinotecan plus 5-fluorouracil and l-leucovorin combination chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080601 |
| [A case of small cell carcinoma of the ureter]. | Hinyokika kiyo. Acta urologica Japonica 20080601 |
| Atorvastatin and cardiovascular risk in the elderly--patient considerations. | Clinical interventions in aging 20080601 |
| Systemic treatments for mesothelioma: standard and novel. | Current treatment options in oncology 20080601 |
| Differential in vitro inhibitory effects of anticancer drugs on tumor-associated carbonic anhydrase isozymes CA IX and CA XII. | Methods and findings in experimental and clinical pharmacology 20080601 |
| Current and emerging therapies for the treatment of age-related macular degeneration. | Clinical ophthalmology (Auckland, N.Z.) 20080601 |
| Targeting colorectal cancer with human anti-EGFR monoclonocal antibodies: focus on panitumumab. | Biologics : targets & therapy 20080601 |
| Chemotherapy and its effect on liver hypertrophy: implications for portal vein embolization and resection. | Seminars in interventional radiology 20080601 |
| [Pharmacogenetics and tumor sensitivity of antineoplastic agents. Application to colorectal cancer]. | La Revue du praticien 20080531 |
| Poly (amino acid) micelle nanocarriers in preclinical and clinical studies. | Advanced drug delivery reviews 20080522 |
| [Systemic treatment of metastatic colorectal cancer]. | Revue medicale suisse 20080521 |
| Antiangiogenic and anticolorectal cancer effects of metronomic irinotecan chemotherapy alone and in combination with semaxinib. | British journal of cancer 20080520 |
| A phase II trial of lomeguatrib and temozolomide in metastatic colorectal cancer. | British journal of cancer 20080520 |
| Treatment with bevacizumab and irinotecan for recurrent high-grade glial tumors. | Cancer 20080515 |
| EPIC: phase III trial of cetuximab plus irinotecan after fluoropyrimidine and oxaliplatin failure in patients with metastatic colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080510 |
| Bortezomib with or without irinotecan in relapsed or refractory colorectal cancer: results from a randomized phase II study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080510 |
| Low expression of gamma-glutamyl hydrolase mRNA in primary colorectal cancer with the CpG island methylator phenotype. | British journal of cancer 20080506 |
| Heterogeneous activity of cytotoxic drugs in patient samples of peritoneal carcinomatosis. | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20080501 |
| Zinc depletion efficiently inhibits pancreatic cancer cell growth by increasing the ratio of antiproliferative/proliferative genes. | Journal of cellular biochemistry 20080501 |
| Irinotecan combined with infusional 5-fluorouracil/folinic acid or capecitabine plus celecoxib or placebo in the first-line treatment of patients with metastatic colorectal cancer. EORTC study 40015. | Annals of oncology : official journal of the European Society for Medical Oncology 20080501 |
| Synergistic antitumor activity of the novel SN-38-incorporating polymeric micelles, NK012, combined with 5-fluorouracil in a mouse model of colorectal cancer, as compared with that of irinotecan plus 5-fluorouracil. | International journal of cancer 20080501 |
| A randomized phase III multicenter trial comparing irinotecan in combination with the Nordic bolus 5-FU and folinic acid schedule or the bolus/infused de Gramont schedule (Lv5FU2) in patients with metastatic colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20080501 |
| Bevacizumab combined with irinotecan for recurrent glioblastoma multiforme--improvement over available therapy? | Nature clinical practice. Neurology 20080501 |
| Isolated hypoxic hepatic perfusion with retrograde outflow in patients with irresectable liver metastases; a new simplified technique in isolated hepatic perfusion. | Annals of surgical oncology 20080501 |
| UGT1A1*28 polymorphism predicts irinotecan-induced severe toxicities without affecting treatment outcome and survival in patients with metastatic colorectal carcinoma. | Cancer 20080501 |
| Salvage chemotherapy with CPT-11 for recurrent temozolomide-refractory anaplastic astrocytoma. | Cancer 20080501 |
| Metastatic colorectal cancer: irinotecan plus infusional, bolus or oral fluoropyrimidines as first-line treatment. | Nature clinical practice. Oncology 20080501 |
| Treatment of advanced or recurrent colorectal cancer with irinotecan in Japan and elsewhere. | Expert opinion on pharmacotherapy 20080501 |
| A novel molecular mechanism for anticancer drug-induced ovarian failure: Irinotecan HCl, an anticancer topoisomerase I inhibitor, induces specific FasL expression in granulosa cells of large ovarian follicles to enhance follicular apoptosis. | International journal of oncology 20080501 |
| Irinotecan HCl, an anticancer topoisomerase I inhibitor, frequently induces ovarian failure in premenopausal and perimenopausal women. | Oncology reports 20080501 |
| Targeted therapy of cancer: new roles for pathologists in colorectal cancer. | Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20080501 |
| Canine model of convection-enhanced delivery of liposomes containing CPT-11 monitored with real-time magnetic resonance imaging: laboratory investigation. | Journal of neurosurgery 20080501 |
| [Chemotherapy associated hepatotoxicity in the treatment of advanced colorectal cancer (CRC)]. | Zeitschrift fur Gastroenterologie 20080501 |
| The use of irinotecan, oxaliplatin and raltitrexed for the treatment of advanced colorectal cancer: systematic review and economic evaluation. | Health technology assessment (Winchester, England) 20080501 |
| Cost-effectiveness of UGT1A1 genotyping in second-line, high-dose, once every 3 weeks irinotecan monotherapy treatment of colorectal cancer. | Pharmacogenomics 20080501 |
| Topoisomerase I inhibitors for the treatment of brain tumors. | Expert review of anticancer therapy 20080501 |
| Key role of topoisomerase I inhibitors in the treatment of recurrent and refractory epithelial ovarian carcinoma. | Expert review of anticancer therapy 20080501 |
| Systemic treatment of colorectal cancer. | Gastroenterology 20080501 |
| Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells is a primary target for therapy with tyrosine kinase inhibitors. | Neoplasia (New York, N.Y.) 20080501 |
| [A case of advanced gastric cancer with peritoneal metastasis successfully treated over 19 months with postoperative chemotherapy after non-curative surgery]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080501 |
| [Recurrent gallbladder carcinoma treated with combination chemotherapy with gemcitabine, CPT-11 and S-1--a successful case with metastatic tumors replaced by marked calcification]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080501 |
| A novel tumor-promoting function residing in the 5' non-coding region of vascular endothelial growth factor mRNA. | PLoS medicine 20080501 |
| Gefitinib in combination with oxaliplatin and 5-fluorouracil in irinotecan-refractory patients with colorectal cancer: a phase I study of the Arbeits gemeinschaft Internistische Onkologie (AIO). | Onkologie 20080501 |
| Preoperative therapy in esophageal cancer. | Clinical advances in hematology & oncology : H&O 20080501 |
| Molecular biomarker development for anti-EGFR therapy: moving beyond EGFR expression. | Clinical colorectal cancer 20080501 |
| Colon cancer: update on adjuvant therapy. | Clinical colorectal cancer 20080501 |
| VEGF 165 b, an antiangiogenic VEGF-A isoform, binds and inhibits bevacizumab treatment in experimental colorectal carcinoma: balance of pro- and antiangiogenic VEGF-A isoforms has implications for therapy. | British journal of cancer 20080422 |
| The role of S-1 in the treatment of gastric cancer. | British journal of cancer 20080422 |
| ERCC1 mRNA levels and survival of advanced gastric cancer patients treated with a modified FOLFOX regimen. | British journal of cancer 20080422 |
| Phase I/II study of S-1 combined with weekly docetaxel in patients with metastatic gastric carcinoma. | British journal of cancer 20080422 |
| A pharmacokinetic and pharmacodynamic study on metronomic irinotecan in metastatic colorectal cancer patients. | British journal of cancer 20080422 |
| Gene expression profiling may improve diagnosis in patients with carcinoma of unknown primary. | British journal of cancer 20080422 |
| Targeting metastatic colorectal cancer in 2008: a long way from 5-FU. | Oncology (Williston Park, N.Y.) 20080415 |
| Capecitabine and irinotecan as first-line treatment of advanced colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080410 |
| The endogenous anti-angiogenic VEGF isoform, VEGF165b inhibits human tumour growth in mice. | British journal of cancer 20080408 |
| Phase II study of capecitabine and oxaliplatin given prior to and concurrently with preoperative pelvic radiotherapy in patients with locally advanced rectal cancer. | British journal of cancer 20080408 |
| Irinotecan+5-fluorouracil with concomitant pre-operative radiotherapy in locally advanced non-resectable rectal cancer: a phase I/II study. | British journal of cancer 20080408 |
| Preservation of the active lactone form of irinotecan using drug eluting beads for the treatment of colorectal cancer metastases. | Journal of controlled release : official journal of the Controlled Release Society 20080407 |
| Involvement of UDP-glucuronosyltransferase activity in irinotecan-induced delayed-onset diarrhea in rats. | Cancer chemotherapy and pharmacology 20080401 |
| Role of cytokines (TNF-alpha, IL-1beta and KC) in the pathogenesis of CPT-11-induced intestinal mucositis in mice: effect of pentoxifylline and thalidomide. | Cancer chemotherapy and pharmacology 20080401 |
| Lopinavir-ritonavir dramatically affects the pharmacokinetics of irinotecan in HIV patients with Kaposi's sarcoma. | Clinical pharmacology and therapeutics 20080401 |
| Randomized phase II study of irinotecan, leucovorin and 5-fluorouracil (ILF) versus cisplatin plus ILF (PILF) combination chemotherapy for advanced gastric cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20080401 |
| Chemosensitivity determinants of irinotecan hydrochloride in hepatocellular carcinoma cell lines. | Basic & clinical pharmacology & toxicology 20080401 |
| Costs associated with intravenous chemotherapy administration in patients with small cell lung cancer: a retrospective claims database analysis. | Current medical research and opinion 20080401 |
| Bevacizumab in combination with irinotecan for patients with recurrent glioblastoma multiforme. | Nature clinical practice. Oncology 20080401 |
| Phase II trial of irinotecan and thalidomide in adults with recurrent glioblastoma multiforme. | Neuro-oncology 20080401 |
| Sequential treatment with SN-38 followed by 5-fluorouracil shows synergistic cytotoxic activity in small cell lung cancer cells. | Oncology reports 20080401 |
| Novel prodrugs of SN38 using multiarm poly(ethylene glycol) linkers. | Bioconjugate chemistry 20080401 |
| [Irinotecan pharmacogenetics in Japanese cancer patients: roles of UGT1A1*6 and *28]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080401 |
| Is irinotecan plus docetaxel useful as second-line therapy in advanced non-small cell lung cancer? | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20080401 |
| The cyclin-dependent kinase inhibitor flavopiridol potentiates the effects of topoisomerase I poisons by suppressing Rad51 expression in a p53-dependent manner. | Cancer research 20080401 |
| DTS-108, a novel peptidic prodrug of SN38: in vivo efficacy and toxicokinetic studies. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080401 |
| Treatment of human colon cancer xenografts with TRA-8 anti-death receptor 5 antibody alone or in combination with CPT-11. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080401 |
| Salvage chemotherapy with biweekly irinotecan, plus 5-fluorouracil and leucovorin in patients with advanced gastric cancer previously treated with fluoropyrimidine, platinum, and taxane. | American journal of clinical oncology 20080401 |
| Anti proliferative activity of ELACY (CP-4055) in combination with cloretazine (VNP40101M), idarubicin, gemcitabine, irinotecan and topotecan in human leukemia and lymphoma cells. | Leukemia & lymphoma 20080401 |
| [Combined irinotecan (CPT-11) and nedaplatin (254-S) therapy for advanced and/or recurrent cervical cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080401 |
| [Multiple hepatic metastases and ovarian metastases of colon cancer responding to combined therapy with S-1 and CPT-11--a case report]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080401 |
| Enhancement of antitumor properties of TRAIL by targeted delivery to the tumor neovasculature. | Molecular cancer therapeutics 20080401 |
| [Antibody treatment in colorectal cancer--what the surgeon needs to know]. | Zentralblatt fur Chirurgie 20080401 |
| Chemotherapy in elderly patients with colorectal cancer. | The oncologist 20080401 |
| Safety of irinotecan and infusional fluorouracil/leucovorin (FOLFIRI) in Japan: a retrospective review of 48 patients with metastatic colorectal cancer. | International journal of clinical oncology 20080401 |
| Small cell carcinoma of the ovary: clinical and biological study. | International journal of clinical oncology 20080401 |
| UGT1A1*28 and other UGT1A polymorphisms as determinants of irinotecan toxicity. | Journal of chemotherapy (Florence, Italy) 20080401 |
| [Three cases of small cell carcinoma of the urinary bladder: a case report]. | Hinyokika kiyo. Acta urologica Japonica 20080401 |
| Management of venous thromboembolism in patients with cancer: role of dalteparin. | Vascular health and risk management 20080401 |
| Prevention of chemotherapy-induced nausea and vomiting: focus on fosaprepitant. | Therapeutics and clinical risk management 20080401 |
| Phase I/II study of oxaliplatin with oral S-1 as first-line therapy for patients with metastatic colorectal cancer. | British journal of cancer 20080325 |
| Met expression is an independent prognostic risk factor in patients with oesophageal adenocarcinoma. | British journal of cancer 20080325 |
| Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial. | Lancet (London, England) 20080322 |
| Alternate statistical tools and limitations in genetic marker association studies in single-arm drug cancer trials. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080320 |
| Pharmacogenetic profiling for cetuximab plus irinotecan therapy in patients with refractory advanced colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080320 |
| Irinotecan/fluorouracil combination in first-line therapy of older and younger patients with metastatic colorectal cancer: combined analysis of 2,691 patients in randomized controlled trials. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080320 |
| Importance of UDP-glucuronosyltransferase 1A1*6 for irinotecan toxicities in Japanese cancer patients. | Cancer letters 20080318 |
| Next generation topoisomerase I inhibitors: Rationale and biomarker strategies. | Biochemical pharmacology 20080315 |
| Novel SN-38-incorporated polymeric micelle, NK012, strongly suppresses renal cancer progression. | Cancer research 20080315 |
| Enzastaurin, a protein kinase C beta inhibitor, suppresses signaling through the ribosomal S6 kinase and bad pathways and induces apoptosis in human gastric cancer cells. | Cancer research 20080315 |
| Irinotecan pharmacogenetics: influence of pharmacodynamic genes. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080315 |
| Novel delivery of SN38 markedly inhibits tumor growth in xenografts, including a camptothecin-11-refractory model. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080315 |
| Population pharmacokinetic data analysis of three phase I studies of matuzumab, a humanised anti-EGFR monoclonal antibody in clinical cancer development. | British journal of cancer 20080311 |
| Inhibition of mTOR pathway by everolimus cooperates with EGFR inhibitors in human tumours sensitive and resistant to anti-EGFR drugs. | British journal of cancer 20080311 |
| Is there a standard of care for the management of advanced pancreatic cancer?. Highlights from the Gastrointestinal Cancers Symposium. Orlando, FL, USA. January 25-27, 2008. | JOP : Journal of the pancreas 20080308 |
| Long term survival on S-1 monotherapy in a patient with recurrent stage IV pancreatic cancer. | JOP : Journal of the pancreas 20080308 |
| Osteosarcoma metastatic to the kidney and iatrogenic hemorrhage. | Pediatric blood & cancer 20080301 |
| Iodine-131-metaiodobenzylguanidine therapy with reduced-intensity allogeneic stem cell transplantation in recurrent neuroblastoma. | Pediatric blood & cancer 20080301 |
| Phase I and pharmacokinetic study of UCN-01 in combination with irinotecan in patients with solid tumors. | Cancer chemotherapy and pharmacology 20080301 |
| Phase II trial of gemcitabine and irinotecan in previously treated patients with small-cell lung cancer. | Cancer chemotherapy and pharmacology 20080301 |
| Functional study of the 830C>G polymorphism of the human carboxylesterase 2 gene. | Cancer chemotherapy and pharmacology 20080301 |
| Response of a thymic mucoepidermoid carcinoma to combination chemotherapy with cisplatin and irinotecan: a case report. | Lung cancer (Amsterdam, Netherlands) 20080301 |
| A novel liposomal irinotecan formulation with significant anti-tumour activity: use of the divalent cation ionophore A23187 and copper-containing liposomes to improve drug retention. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080301 |
| ERCC1 protein expression predicts the response of cisplatin-based neoadjuvant chemotherapy in non-small-cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20080301 |
| KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximab. | Annals of oncology : official journal of the European Society for Medical Oncology 20080301 |
| Tumor response to neoadjuvant chemoradiation in rectal cancer: predictor for surgical morbidity? | International journal of colorectal disease 20080301 |
| Efficacy of combination chemotherapy with irinotecan (CPT-11) plus capecitabine in patients with metastatic or advanced colorectal carcinoma--a dual-centre phase II study: the MAC-6. | Clinical oncology (Royal College of Radiologists (Great Britain)) 20080301 |
| An improved human carboxylesterase for enzyme/prodrug therapy with CPT-11. | Cancer gene therapy 20080301 |
| Carboxylesterase 2 is downregulated in colorectal cancer following progression of the disease. | Cancer investigation 20080301 |
| Safety of repeated administrations of ixabepilone given as a 3-hour infusion every other week in combination with irinotecan in patients with advanced malignancies. | European journal of cancer (Oxford, England : 1990) 20080301 |
| Where to position monoclonal antibodies in first-line treatment of advanced colorectal cancer. | European journal of cancer (Oxford, England : 1990) 20080301 |
| Small cell lung cancer. | Mayo Clinic proceedings 20080301 |
| U.S. Food and Drug Administration approval: panitumumab for epidermal growth factor receptor-expressing metastatic colorectal carcinoma with progression following fluoropyrimidine-, oxaliplatin-, and irinotecan-containing chemotherapy regimens. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080301 |
| Induction chemotherapy with carboplatin, irinotecan, and paclitaxel followed by high dose three-dimension conformal thoracic radiotherapy (74 Gy) with concurrent carboplatin, paclitaxel, and gefitinib in unresectable stage IIIA and stage IIIB non-small cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20080301 |
| Complete response of CNS-involved olfactory neuroendocrine tumor using multimodal therapy. | Onkologie 20080301 |
| [A case of multidrug-resistant squamous cell lung carcinoma responding to S-1 plus CPT-11 combination chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080301 |
| [A patient with small cell lung cancer who developed a drug eruption due to concomitant therapy with carboplatin and etoposide]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080301 |
| [A long survival case of advanced colon cancer with lung metastasis and cancerous pleuritis responding to CPT-11 and S-1 combination therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080301 |
| Gilbert's Syndrome and irinotecan toxicity: combination with UDP-glucuronosyltransferase 1A7 variants increases risk. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080301 |
| S-1 monotherapy as a neoadjuvant treatment for locally advanced gastric cancer. | The Korean journal of internal medicine 20080301 |
| Cetuximab plus oxaliplatin-based chemotherapy in the treatment of colorectal cancer. | Expert review of anticancer therapy 20080301 |
| Novel systemic therapies for small cell lung cancer. | Journal of the National Comprehensive Cancer Network : JNCCN 20080301 |
| New therapeutic directions for advanced pancreatic cancer: targeting the epidermal growth factor and vascular endothelial growth factor pathways. | The oncologist 20080301 |
| Sequential vs combination colorectal cancer therapy sparks debate. | British journal of hospital medicine (London, England : 2005) 20080301 |
| Cetuximab plus XELIRI or XELOX for first-line therapy of metastatic colorectal cancer. | Clinical colorectal cancer 20080301 |
| Pathologic complete response to neoadjuvant FOLFOX in combination with bevacizumab in unresectable metastatic colorectal carcinoma. | Clinical colorectal cancer 20080301 |
| Southwest Oncology Group phase II study of irinotecan in patients with advanced transitional cell carcinoma of the urothelium that progressed after platinum-based chemotherapy. | Clinical genitourinary cancer 20080301 |
| [Current therapeutic options for liver metastasis]. | Revista medica de Chile 20080301 |
| [Irinotecan plus fuorouracil/leucovorin (FOLFIRI) as a second line chemotherapy for refractory or metastatic colorectal cancer]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20080301 |
| Anti-cancer effects of xanthones from pericarps of mangosteen. | International journal of molecular sciences 20080301 |
| Treatment of age-related macular degeneration: focus on ranibizumab. | Clinical ophthalmology (Auckland, N.Z.) 20080301 |
| Intestinal perforation in colorectal cancers treated with bevacizumab (Avastin). | Cancer research and treatment : official journal of Korean Cancer Association 20080301 |
| Bevacizumab in the therapy for refractory metastatic colorectal cancer. | Biologics : targets & therapy 20080301 |
| Erlotinib in the treatment of advanced pancreatic cancer. | Biologics : targets & therapy 20080301 |
| Impacts of excision repair cross-complementing gene 1 (ERCC1), dihydropyrimidine dehydrogenase, and epidermal growth factor receptor on the outcomes of patients with advanced gastric cancer. | British journal of cancer 20080226 |
| Randomised phase II trial of irinotecan plus cisplatin vs irinotecan, cisplatin plus etoposide repeated every 3 weeks in patients with extensive-disease small-cell lung cancer. | British journal of cancer 20080226 |
| A phase II study to determine the ability of gefitinib to reverse fluoropyrimidine resistance in metastatic colorectal cancer (the INFORM study). | British journal of cancer 20080226 |
| Enhancement of the antitumor activity of ionising radiation by nimotuzumab, a humanised monoclonal antibody to the epidermal growth factor receptor, in non-small cell lung cancer cell lines of differing epidermal growth factor receptor status. | British journal of cancer 20080226 |
| Bevacizumab plus irinotecan in recurrent glioblastoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080220 |
| Rapid screening of antineoplastic candidates for the human organic anion transporter OATP1B3 substrates using fluorescent probes. | Cancer letters 20080218 |
| Nonplatinum-based chemotherapy with irinotecan plus docetaxel for advanced or metastatic olfactory neuroblastoma: a retrospective analysis of 12 cases. | Cancer 20080215 |
| Irinophore C: a liposome formulation of irinotecan with substantially improved therapeutic efficacy against a panel of human xenograft tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080215 |
| Spectrofluorimetric determination of irinotecan in the presence of oxidant agents and metal ions. | Talanta 20080215 |
| Multicenter phase II study of docetaxel plus oxaliplatin combination chemotherapy in patients with advanced gastric cancer: Daegu Gyeongbuk Oncology Group. | British journal of cancer 20080212 |
| G2 checkpoint abrogation and checkpoint kinase-1 targeting in the treatment of cancer. | British journal of cancer 20080212 |
| Re: UGT1A1*28 genotype and irinotecan-induced neutropenia: dose matters. | Journal of the National Cancer Institute 20080206 |
| Phase-II study of dose attenuated schedule of irinotecan, capecitabine, and celecoxib in advanced colorectal cancer. | Cancer chemotherapy and pharmacology 20080201 |
| A phase II study of irinotecan in combination with doxifluridine, an intermediate form of capecitabine, in patients with metastatic colorectal cancer. | Cancer chemotherapy and pharmacology 20080201 |
| Reducing irinotecan-associated diarrhea in children. | Pediatric blood & cancer 20080201 |
| Combination of topotecan and etoposide as a salvage treatment for patients with recurrent small cell lung cancer following irinotecan and platinum first-line chemotherapy. | Cancer chemotherapy and pharmacology 20080201 |
| Reduced expression of DNA topoisomerase I in SF295 human glioblastoma cells selected for resistance to homocamptothecin and diflomotecan. | Molecular pharmacology 20080201 |
| A phase Ib dose-escalation study of erlotinib, capecitabine and oxaliplatin in metastatic colorectal cancer patients. | Annals of oncology : official journal of the European Society for Medical Oncology 20080201 |
| Tumor targeting carboxylesterase fused with anti-CEA scFv improve the anticancer effect with a less toxic dose of irinotecan. | Cancer gene therapy 20080201 |
| Excess toxicity associated with docetaxel and irinotecan in patients with metastatic, gemcitabine-refractory pancreatic cancer: results of a phase II study. | Cancer investigation 20080201 |
| New homocamptothecins: synthesis, antitumor activity, and molecular modeling. | Bioorganic & medicinal chemistry 20080201 |
| Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment. | European journal of clinical pharmacology 20080201 |
| Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: updated results from the BICC-C study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080201 |
| The EGFR-STAT3 oncogenic pathway up-regulates the Eme1 endonuclease to reduce DNA damage after topoisomerase I inhibition. | Cancer research 20080201 |
| Capecitabine plus oxaliplatin for the treatment of colorectal cancer. | Expert review of anticancer therapy 20080201 |
| Defective p53 signaling in p53 wild-type tumors attenuates p21waf1 induction and cyclin B repression rendering them sensitive to Chk1 inhibitors that abrogate DNA damage-induced S and G2 arrest. | Molecular cancer therapeutics 20080201 |
| [CPT-11 (Irinotecan)]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080201 |
| [Clinical experience of second-line chemotherapy with S-1/CPT-11 for highly advanced gastric cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080201 |
| [Two cases with recurrent non-small cell lung cancer successfully treated with cisplatin and S-1]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080201 |
| [A case of long-term survival of postoperative brain metastasis of small cell lung cancer effectively treated with chemotherapy, whole brain radiotherapy and stereotactic radiosurgery]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080201 |
| Gene directed enzyme prodrug therapy for ovarian cancer: could GDEPT become a promising treatment against ovarian cancer? | Anti-cancer agents in medicinal chemistry 20080201 |
| Administration of cetuximab every 2 weeks in the treatment of metastatic colorectal cancer: an effective, more convenient alternative to weekly administration? | The oncologist 20080201 |
| The impact of chemotherapy on overall survival and quality of life of patients with metastatic colorectal cancer: a review of phase III trials. | Journal of chemotherapy (Florence, Italy) 20080201 |
| A retrospective study of bifractionated CPT-11 with LF5FU infusion (FOLFIRI-3) in colorectal cancer patients pretreated with oxaliplatin and CPT-11 containing chemotherapies. | American journal of clinical oncology 20080201 |
| A review of topotecan in combination chemotherapy for advanced cervical cancer. | Therapeutics and clinical risk management 20080201 |
| Systemic and targeted therapy for advanced colon cancer. | Expert review of gastroenterology & hepatology 20080201 |
| New insights into the role of age and carcinoembryonic antigen in the prognosis of colorectal cancer. | British journal of cancer 20080129 |
| Clinicopathological and prognostic significance of EGFR, VEGF, and HER2 expression in cholangiocarcinoma. | British journal of cancer 20080129 |
| Safety, tolerability and pharmacokinetics of intravenous ghrelin for cancer-related anorexia/cachexia: a randomised, placebo-controlled, double-blind, double-crossover study. | British journal of cancer 20080129 |
| Pharmacological targeting of NF-kappaB potentiates the effect of the topoisomerase inhibitor CPT-11 on colon cancer cells. | British journal of cancer 20080129 |
| A phase II study of paclitaxel and capecitabine as a first-line combination chemotherapy for advanced gastric cancer. | British journal of cancer 20080129 |
| [Molecular targeted therapy in colorectal cancer]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20080117 |
| [Palliative chemotherapy and radiotherapy for metastatic colorectal cancer]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20080117 |
| Application of distance matrices to define associations between acute toxicities in colorectal cancer patients receiving chemotherapy. | Cancer 20080115 |
| Colorectal liver metastases contract centripetally with a response to chemotherapy: a histomorphologic study. | Cancer 20080115 |
| A combination of gefitinib and FOLFOX-4 as first-line treatment in advanced colorectal cancer patients. A GISCAD multicentre phase II study including a biological analysis of EGFR overexpression, amplification and NF-kB activation. | British journal of cancer 20080115 |
| Cetuximab potentiates oxaliplatin cytotoxic effect through a defect in NER and DNA replication initiation. | British journal of cancer 20080115 |
| Response-independent survival benefit in metastatic colorectal cancer: a comparative analysis of N9741 and AVF2107. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080110 |
| Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080110 |
| Comparison of results of a pilot study of alternating vincristine/doxorubicin/cyclophosphamide and etoposide/ifosfamide with IRS-IV in intermediate risk rhabdomyosarcoma: a report from the Children's Oncology Group. | Pediatric blood & cancer 20080101 |
| The combination of capecitabine and irinotecan in treating 5-Fluorouracil- and Oxaliplatin-pretreated metastatic colorectal cancer. | Cancer chemotherapy and pharmacology 20080101 |
| A phase I study of capecitabine and a modulatory dose of irinotecan in metastatic breast cancer. | Cancer chemotherapy and pharmacology 20080101 |
| A phase II trial of modified weekly irinotecan and cisplatin for chemotherapy-naïve patients with metastatic or recurrent squamous cell carcinoma of the esophagus. | Cancer chemotherapy and pharmacology 20080101 |
| Pneumatosis intestinalis and portal venous gas without bowel ischemia in a patient treated with irinotecan and cisplatin. | Digestive diseases and sciences 20080101 |
| Influence of the organic anion-transporting polypeptide 1B1 (OATP1B1) polymorphisms on irinotecan-pharmacokinetics and clinical outcome of patients with advanced non-small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20080101 |
| A phase II study of biweekly irinotecan and cisplatin for patients with extensive stage disease small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20080101 |
| Third-line therapy for metastatic colorectal cancer. | Cancer chemotherapy and pharmacology 20080101 |
| Hepatic arterial infusion of oxaliplatin and intravenous LV5FU2 in unresectable liver metastases from colorectal cancer after systemic chemotherapy failure. | Annals of surgical oncology 20080101 |
| Improved long-term outcome of surgery for advanced colorectal liver metastases: reasons and implications for management on the basis of a severity score. | Annals of surgical oncology 20080101 |
| Irinotecan-induced central nervous system toxicity. Report on two cases and review of the literature. | Acta oncologica (Stockholm, Sweden) 20080101 |
| Thymidylate synthase and microsatellite instability in colorectal cancer: implications for disease free survival, treatment response and survival with metastases. | Acta oncologica (Stockholm, Sweden) 20080101 |
| Colorectal cancer metastasis resectability after treatment with the combination of oxaliplatin, irinotecan and 5-fluorouracil. Final results of a phase II study. | Acta oncologica (Stockholm, Sweden) 20080101 |
| The potential role of pemetrexed in gastrointestinal cancer. | Chemotherapy 20080101 |
| Low response rate of second-line chemotherapy for recurrent or refractory clear cell carcinoma of the ovary: a retrospective Japan Clear Cell Carcinoma Study. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20080101 |
| Carbon beam therapy in recurrent ovarian cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20080101 |
| Outpatient chemotherapy plus radiotherapy in sarcomas: improving cancer control with radiosensitizing agents. | Cancer control : journal of the Moffitt Cancer Center 20080101 |
| Treatment of metastatic urachal carcinoma in an elderly woman. | Nature clinical practice. Oncology 20080101 |
| Fatal tumor lysis syndrome after irinotecan/5-FU/folinic acid/bevacizumab-containing therapy in a patient heavily pretreated for metastatic colon cancer. | Acta oncologica (Stockholm, Sweden) 20080101 |
| Addition of bevacizumab to irinotecan- and oxaliplatin-based preoperative chemotherapy regimens does not increase morbidity after resection of colorectal liver metastases. | Journal of the American College of Surgeons 20080101 |
| Phase I study of induction chemotherapy and concomitant chemoradiotherapy with irinotecan, carboplatin, and paclitaxel for stage III non-small cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20080101 |
| Phase I pharmacokinetic/pharmacodynamic study of EKB-569, an irreversible inhibitor of the epidermal growth factor receptor tyrosine kinase, in combination with irinotecan, 5-fluorouracil, and leucovorin (FOLFIRI) in first-line treatment of patients with metastatic colorectal cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080101 |
| Should tumor VEGF expression influence decisions on combining low-dose chemotherapy with antiangiogenic therapy? Preclinical modeling in ovarian cancer. | Journal of translational medicine 20080101 |
| [The effect of the histoculture drug response assay (HDRA) based perioperative chemotherapy for non-small cell lung cancer]. | Kyobu geka. The Japanese journal of thoracic surgery 20080101 |
| Cerebrospinal fluid matrix metalloproteinase-9 increases during treatment of recurrent malignant gliomas. | Cerebrospinal fluid research 20080101 |
| [A pilot study of irinotecan hydrochloride(CPT-11)and cisplatin(CDDP)combination chemotherapy for previously treated non-small cell lung cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080101 |
| [Irinotecan plus gemcitabine(IRINOGEM)in the treatment of biliary malignancies]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080101 |
| Preoperative irinotecan/5-FU/leucovorin plus concurrent radiotherapy in rectal cancer. | Gan to kagaku ryoho. Cancer & chemotherapy 20080101 |
| [An elderly case of recurrent colon cancer responding to weekly S-1 chemotherapy leading to partial response]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080101 |
| Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma. | PLoS medicine 20080101 |
| Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells. | Molecular cancer 20080101 |
| DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines. | Molecular cancer 20080101 |
| Severe skin reaction secondary to concomitant radiotherapy plus cetuximab. | Radiation oncology (London, England) 20080101 |
| [Predictive factors of response to anti-EGFR treatments in colorectal cancer]. | Bulletin du cancer 20080101 |
| Chemotherapy-and cancer-related nausea and vomiting. | Current oncology (Toronto, Ont.) 20080101 |
| Synergy between cetuximab and chemotherapy in tumors of the gastrointestinal tract. | The oncologist 20080101 |
| Chemoembolisation of rat colorectal liver metastases with drug eluting beads loaded with irinotecan or doxorubicin. | Clinical & experimental metastasis 20080101 |
| ERCC2 2251A>C genetic polymorphism was highly correlated with early relapse in high-risk stage II and stage III colorectal cancer patients: a preliminary study. | BMC cancer 20080101 |
| Guidelines for chemotherapy of biliary tract and ampullary carcinomas. | Journal of hepato-biliary-pancreatic surgery 20080101 |
| Triplet combination of fluoropyrimidines, oxaliplatin, and irinotecan in the first-line treatment of metastatic colorectal cancer. | Clinical colorectal cancer 20080101 |
| Second-line management of metastatic colorectal cancer. | Clinical colorectal cancer 20080101 |
| Phase II trial of T138067, a novel microtubule inhibitor, in patients with metastatic, refractory colorectal carcinoma. | Clinical colorectal cancer 20080101 |
| Efficacy and skin toxicity management with cetuximab in metastatic colorectal cancer: outcomes from an oncologic/dermatologic cooperation. | Clinical colorectal cancer 20080101 |
| Second-line chemotherapy use in metastatic colon cancer varies by disease responsiveness. | Clinical colorectal cancer 20080101 |
| Chemotherapy for brain metastases in small-cell lung cancer. | Clinical lung cancer 20080101 |
| Opossum carboxylesterases: sequences, phylogeny and evidence for CES gene duplication events predating the marsupial-eutherian common ancestor. | BMC evolutionary biology 20080101 |
| Phase I/II study of 24-hour infusion of irinotecan combined with oral UFT for metastatic colorectal cancer. | Chemotherapy 20080101 |
| Bevacizumab: a review of its use in metastatic colorectal cancer. | Drugs 20080101 |
| Targeting the EGFR, VEGFR, and PDGFR on colon cancer cells and stromal cells is required for therapy. | Clinical & experimental metastasis 20080101 |
| Pharmacogenomics of drug-metabolizing enzymes and drug transporters in chemotherapy. | Methods in molecular biology (Clifton, N.J.) 20080101 |
| ABCG2: structure, function and role in drug response. | Expert opinion on drug metabolism & toxicology 20080101 |
| Chronic myeloid leukemia following the treatment of rectal adenocarcinoma. | Medical oncology (Northwood, London, England) 20080101 |
| Meta-analysis of randomized trials: evaluation of benefit from gemcitabine-based combination chemotherapy applied in advanced pancreatic cancer. | BMC cancer 20080101 |
| Small cell carcinoma of the extrahepatic bile duct diagnosed with EUS-FNA and effectively treated with chemoradiation. | Internal medicine (Tokyo, Japan) 20080101 |
| Drug waste minimisation and cost-containment in Medical Oncology: two-year results of a feasibility study. | BMC health services research 20080101 |
| Changes of immunological parameters reflect quality of life-related toxicity during chemotherapy in patients with advanced colorectal cancer. | Anticancer research 20080101 |
| Successful treatment with S-1 plus CPT-11 for lymph node metastasis from colon cancer: report of a case. | Anticancer research 20080101 |
| A test of highly optimized tolerance reveals fragile cell-cycle mechanisms are molecular targets in clinical cancer trials. | PloS one 20080101 |
| WITHDRAWN: Irinotecan plus weekly 5-fluorouracil and leucovorin as salvage treatment for patients with metastatic colorectal cancer: a phase II trial. Dig Dis 2007;25:100-5. | Digestive diseases (Basel, Switzerland) 20080101 |
| Importance of response to neoadjuvant chemotherapy in potentially curable colorectal cancer liver metastases. | BMC cancer 20080101 |
| Principal component analysis for the comparison of metabolic profiles from human rectal cancer biopsies and colorectal xenografts using high-resolution magic angle spinning 1H magnetic resonance spectroscopy. | Molecular cancer 20080101 |
| Metastatic rectal adenocarcinoma within haemorrhoids: a case report. | Journal of medical case reports 20080101 |
| Identification of novel vascular markers through gene expression profiling of tumor-derived endothelium. | BMC genomics 20080101 |
| Epidemiology and management options for colorectal cancer in children. | Paediatric drugs 20080101 |
| Hydroxycamptothecin-loaded nanoparticles enhance target drug delivery and anticancer effect. | BMC biotechnology 20080101 |
| Capecitabine, alone and in combination, in the management of patients with colorectal cancer: a review of the evidence. | Drugs 20080101 |
| Design, synthesis and development of novel camptothecin drugs. | Current pharmaceutical design 20080101 |
| Current status of clinical trials for small cell lung cancer. | Reviews on recent clinical trials 20080101 |
| Chemotherapy with gemcitabine in advanced biliary tract carcinoma. | Reviews on recent clinical trials 20080101 |
| Management of the hepatic lymph nodes during resection of liver metastases from colorectal cancer: a systematic review. | HPB surgery : a world journal of hepatic, pancreatic and biliary surgery 20080101 |
| PPAR Ligands for Cancer Chemoprevention. | PPAR research 20080101 |
| Present treatment and future expectations in advanced pancreatic cancer. | Anticancer research 20080101 |
| Modified FOLFOX-6 chemotherapy in advanced gastric cancer: Results of phase II study and comprehensive analysis of polymorphisms as a predictive and prognostic marker. | BMC cancer 20080101 |
| Cellular response to irinotecan in colon cancer cell lines showing differential response to 5-fluorouracil. | Anticancer research 20080101 |
| Saturated fatty acids modulate cell response to DNA damage: implication for their role in tumorigenesis. | PloS one 20080101 |
| PPARgamma in Neuroblastoma. | PPAR research 20080101 |
| Dose escalation study of amrubicin in combination with fixed-dose irinotecan in patients with extensive small-cell lung cancer. | Oncology 20080101 |
| High-dose irinotecan plus LV5FU2 or simplified LV5FU (HD-FOLFIRI) for patients with untreated metastatic colorectal cancer: a new way to allow resection of liver metastases? | Oncology 20080101 |
| Drug interaction prediction using ontology-driven hypothetical assertion framework for pathway generation followed by numerical simulation. | BMC bioinformatics 20080101 |
| A polymorphism of EGFR extracellular domain is associated with progression free-survival in metastatic colorectal cancer patients receiving cetuximab-based treatment. | BMC cancer 20080101 |
| Modified CAPOX (capecitabine plus oxaliplatin) regimen every two weeks as second-line treatment in patients with advanced colorectal cancer previously treated with irinotecan-based frontline therapy: a multicenter phase II study. | Oncology 20080101 |
| Genotyping panel for assessing response to cancer chemotherapy. | BMC medical genomics 20080101 |
| Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy. | PloS one 20080101 |
| [Bevacizumab/irinotecan. An active treatment for recurrent high grade gliomas: preliminary results of an ANOCEF Multicenter Study]. | Revue neurologique 20080101 |
| Outpatient and home chemotherapy with novel local control strategies in desmoplastic small round cell tumor. | Sarcoma 20080101 |
| Combined effects of 5-fluorouracil, folinic acid and oxaliplatin on the expression of carcinoembryonic antigen in human colon cancer cells: pharmacological basis to develop an active antitumor immunochemotherapy. | Journal of experimental & clinical cancer research : CR 20080101 |
| PPARgamma and MEK Interactions in Cancer. | PPAR research 20080101 |
| Gemcitabine based combination chemotherapy in advanced pancreatic cancer-indirect comparison. | BMC cancer 20080101 |
| Oct-4 expression maintained cancer stem-like properties in lung cancer-derived CD133-positive cells. | PloS one 20080101 |
| A phase I trial of CPT-11 and S-1 combination chemotherapy in patients with metastatic colorectal cancer. | Hepato-gastroenterology 20080101 |
| Early distant relapse after optimal local control in locally advanced rectal cancer. | International seminars in surgical oncology : ISSO 20080101 |
| Palliative treatment for elderly patients with colon cancer in ten Italian medical oncology units. | Anticancer research 20080101 |
| Complete response obtained and maintained by combination of S-1 and CPT-11 in hepatic metastases of colon cancer: a case report. | Anticancer research 20080101 |
| Irinotecan plus capecitabine as first-line chemotherapy in advanced colorectal cancer. | Anticancer research 20080101 |
| Diminishing impact of preoperative carcinoembryonic antigen (CEA) in prognosis of Dukes' C colorectal cancer. | Anticancer research 20080101 |
| Portal vein gas in emergency surgery. | World journal of emergency surgery : WJES 20080101 |
| Adrenalectomy for solitary adrenal metastasis from colorectal cancer: A case report. | Cases journal 20080101 |
| Efficacy of laser capture microdissection plus RT-PCR technique in analyzing gene expression levels in human gastric cancer and colon cancer. | BMC cancer 20080101 |
| A classification model to predict synergism/antagonism of cytotoxic mixtures using protein-drug docking scores. | BMC pharmacology 20080101 |
| Primary small-cell neuroendocrine carcinoma of the breast: report of a case. | Surgery today 20080101 |
| Proteomic approaches in understanding action mechanisms of metal-based anticancer drugs. | Metal-based drugs 20080101 |
| Clinical drugs that interact with St. John's wort and implication in drug development. | Current pharmaceutical design 20080101 |
| Epigenetic mechanisms involved in differential MDR1 mRNA expression between gastric and colon cancer cell lines and rationales for clinical chemotherapy. | BMC gastroenterology 20080101 |
| Gene expression time-series analysis of camptothecin effects in U87-MG and DBTRG-05 glioblastoma cell lines. | Molecular cancer 20080101 |
| Potential value of PTEN in predicting cetuximab response in colorectal cancer: an exploratory study. | BMC cancer 20080101 |
| The inverse starving test is not a suitable provocation test for Gilbert's syndrome. | BMC research notes 20080101 |
| Weekly irinotecan plus protracted venous fluorouracil infusion (WI-FI) in advanced colorectal cancer: a phase II study. | Anticancer research 20080101 |
| Cetuximab with hepatic arterial infusion of chemotherapy for the treatment of colorectal cancer liver metastases. | Anticancer research 20080101 |
| Pilot study of combination chemotherapy using irinotecan plus S-1 for metastatic pancreatic cancer. | Oncology 20080101 |
| Cytomegalovirus colitis after systemic chemotherapy in a patient with recurrent colon cancer: a case report. | Journal of medical case reports 20080101 |
| Bortezomib as a therapeutic candidate for neuroblastoma. | Journal of experimental therapeutics & oncology 20080101 |
| Late recurrence of large peri-stomal metastasis following abdomino-perineal resection of rectal cancer. | World journal of surgical oncology 20080101 |
| Spotlight on bevacizumab in metastatic colorectal cancer. | BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20080101 |
| In GFP with high risk HPV-18E6 fusion protein expressed 293T and MCF-7 cells, the endogenous wild-type p53 could be transiently phosphorylated at multiple sites. | Journal of experimental & clinical cancer research : CR 20080101 |
| Germline polymorphisms as modulators of cancer phenotypes. | BMC medicine 20080101 |
| Molecular imaging suggests efficacy of bevacizumab beyond the second line in advanced colorectal cancer patients. | Chemotherapy 20080101 |
| EGFR expression in gallbladder carcinoma in North America. | International journal of medical sciences 20080101 |
| Intestinal permeability and toxicity of second-line therapeutic agents in ovarian cancer. | Tumori 20080101 |
| Novel therapies in breast cancer: what is new from ASCO 2008. | Journal of hematology & oncology 20080101 |
| First- and second-line treatment of advanced metastatic non-small-cell lung cancer: a global view. | BMC proceedings 20080101 |
| SCLC extensive disease--treatment guidance by extent or/and biology of response? | Radiation oncology (London, England) 20080101 |
| Gefitinib increases serum concentrations of oral irinotecan and SN-38 without increasing the biliary concentration of SN-38 in rats. | Chemotherapy 20080101 |
| Bevacizumab and irinotecan in the treatment of recurrent malignant gliomas. | Cancer journal (Sudbury, Mass.) 20080101 |
| Patient with advanced intrahepatic cholangiocarcinoma with long-term survival successfully treated with a combination of surgery and chemotherapy. | Journal of hepato-biliary-pancreatic surgery 20080101 |
| Bevacizumab improves the overall and progression-free survival of patients with metastatic colorectal cancer treated with 5-fluorouracil-based regimens irrespective of baseline risk. | Oncology 20080101 |
| A randomised, double-masked phase III/IV study of the efficacy and safety of Avastin(R) (Bevacizumab) intravitreal injections compared to standard therapy in subjects with choroidal neovascularisation secondary to age-related macular degeneration: clinical trial design. | Trials 20080101 |
| First-in-class, first-in-human phase I results of targeted agents: highlights of the 2008 American society of clinical oncology meeting. | Journal of hematology & oncology 20080101 |
| Randomized phase II study with two gemcitabine- and docetaxel-based combinations as first-line chemotherapy for metastatic non-small cell lung cancer. | Journal of translational medicine 20080101 |
| Role of drug transporters and drug accumulation in the temporal acquisition of drug resistance. | BMC cancer 20080101 |
| [Molecular diagnosis in oncology]. | Molekuliarnaia biologiia 20080101 |
| Variability and function of family 1 uridine-5'-diphosphate glucuronosyltransferases (UGT1A). | Critical reviews in clinical laboratory sciences 20080101 |
| Analysis of costs associated with administration of intravenous single-drug therapies in metastatic breast cancer in a U.S. population. | Journal of managed care pharmacy : JMCP 20080101 |
| Modified irinotecan plus bolus 5-fluorouracil/L-leucovorin for metastatic colorectal cancer at a single institution in Japan. | Journal of gastroenterology 20080101 |
| Experience with adjuvant chemotherapy for pseudomyxoma peritonei secondary to mucinous adenocarcinoma of the appendix with oxaliplatin/fluorouracil/leucovorin (FOLFOX4). | World journal of surgical oncology 20080101 |
| Biweekly oxaliplatin and irinotecan chemotherapy in advanced gastric cancer. A first-line multicenter phase II trial of the Arbeitsgemeinschaft Medikamentöse Tumortherapie (AGMT). | Anticancer research 20080101 |
| Phase I study of irinotecan combined with mitomycin-C and 5-fluorouracil for gynecological malignancies: the JGOG study. | Anticancer research 20080101 |
| Gemcitabine and protracted 5-fluorouracil infusion as third-line chemotherapy in refractory colorectal cancer patients. | Anticancer research 20080101 |
| Bevacizumab added to the irinotecan and capecitabine combination for advanced colorectal cancer: a well-tolerated, active and convenient regimen. | Anticancer research 20080101 |
| [Adjuvant therapy of colon carcinoma]. | Onkologie 20080101 |
| The Adnectin CT-322 is a novel VEGF receptor 2 inhibitor that decreases tumor burden in an orthotopic mouse model of pancreatic cancer. | BMC cancer 20080101 |
| Alteration of Drug Sensitivity in Human Colon Cancer Cells after Exposure to Heat: Implications for Liver Metastasis Therapy using RFA and Chemotherapy. | International journal of clinical and experimental medicine 20080101 |
| The role of thrombospondin 1 on intestinal inflammation and carcinogenesis. | Biomarker insights 20080101 |
| Sequential or combination chemotherapy for a patient with mCRC? | Cancer treatment reviews 20080101 |
| A dilemma in geriatric oncology: malignant bowel obstruction in an 81-year-old man. | Cancer treatment reviews 20080101 |
| Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients. | PloS one 20080101 |
| Thymidylate synthase, dihydropyrimidine dehydrogenase, ERCC1, and thymidine phosphorylase gene expression in primary and metastatic gastrointestinal adenocarcinoma tissue in patients treated on a phase I trial of oxaliplatin and capecitabine. | BMC cancer 20080101 |
| The management of cancer in the elderly: targeted therapies in oncology. | Immunity & ageing : I & A 20080101 |
| Clinical Use of PPARgamma Ligands in Cancer. | PPAR research 20080101 |
| Combination chemotherapy with cisplatin and irinotecan in patients with adenocarcinoma of the small intestine. | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20080101 |
| The Role of PPARgamma Receptors and Leukotriene B(4) Receptors in Mediating the Effects of LY293111 in Pancreatic Cancer. | PPAR research 20080101 |
| Treatment with cetuximab, bevacizumab and irinotecan in heavily pretreated patients with metastasized colorectal cancer. | Anticancer research 20080101 |
| Chemotherapy prior to hepatic resection for colorectal liver metastases: helpful until harmful? | Digestive surgery 20080101 |
| The addition of bevacizumab to fluoropyrimidine, irinotecan and oxaliplatin-based therapy improves survival for patients with metastatic colorectal cancer (CRC): combined analysis of efficacy. | Acta chirurgica Iugoslavica 20080101 |
| Current approaches to gastric cancer in Korea. | Gastrointestinal cancer research : GCR 20080101 |
| Rationale for combining biotherapy in the treatment of advanced colon cancer. | Gastrointestinal cancer research : GCR 20080101 |
| New pathways for alimentary mucositis. | Journal of oncology 20080101 |
| Reinduction of bevacizumab in combination with pegylated liposomal Doxorubicin in a patient with recurrent glioblastoma multiforme who progressed on bevacizumab/irinotecan. | Journal of oncology 20080101 |
| TACE of liver metastases from colorectal cancer adopting irinotecan-eluting beads: beneficial effect of palliative intra-arterial lidocaine and post-procedure supportive therapy on the control of side effects. | Hepato-gastroenterology 20080101 |
| Combination Therapy of PPARgamma Ligands and Inhibitors of Arachidonic Acid in Lung Cancer. | PPAR research 20080101 |
| Advanced gastric cancer: an update and future directions. | Gastrointestinal cancer research : GCR 20080101 |
| Successful and well-tolerated second line therapy with cetuximab, irinotecan, and raltitrexed in progressive liver disease due to metastatic colon cancer. | Journal of gastrointestinal cancer 20080101 |
| Medical resource use and cost of different first-line treatments for metastatic colorectal cancer in Brazil. | Journal of medical economics 20080101 |
| Multicentric small cell neuroendocrine neoplasm of the renal pelvis and ureter with concomitant focal high-grade urothelial carcinoma of the ureter: A case report. | Indian journal of urology : IJU : journal of the Urological Society of India 20080101 |
| Docetaxel and irinotecan as first-line chemotherapy in patients with advanced non-small-cell lung cancer: a pilot study. | Le Journal medical libanais. The Lebanese medical journal 20080101 |
| Solid-phase extraction and reverse-phase HPLC: application to study the urinary excretion pattern of benzophenone-3 and its metabolite 2,4-dihydroxybenzophenone in human urine. | Analytical chemistry insights 20080101 |
| Next-generation anthracycline for the management of small cell lung cancer: focus on amrubicin. | Drug design, development and therapy 20080101 |
| Targeted treatment of advanced and metastaticbreast cancer with lapatinib. | OncoTargets and therapy 20080101 |
| The efficacy and safety of irinotecan cisplatin and mitomycin chemotherapy in sunitinib pre-treated metastatic clear cell renal cancer. | OncoTargets and therapy 20080101 |
| Topotecan in the treatment of relapsed small cell lung cancer. | OncoTargets and therapy 20080101 |
| Comparison of vinorelbine-Cisplatin with gemcitabine-Cisplatin in patients with advanced non-small cell lung cancer. | Clinical medicine. Circulatory, respiratory and pulmonary medicine 20080101 |
| A review on plant-derived natural products and their analogs with anti-tumor activity. | Indian journal of pharmacology 20080101 |
| Direct evidence that heterogeneity necessitates and limits the use of multidrug chemotherapy in colon cancer. | Molecular medicine reports 20080101 |
| Organic anion transporting polypeptide 1B3 (OATP1B3) is overexpressed in colorectal tumors and is a predictor of clinical outcome. | Clinical and experimental gastroenterology 20080101 |
| Oxaliplatin for metastatic colon cancer in a patient with renal failure. | Clinical medicine. Oncology 20080101 |
| Leptomeningeal metastases in a patient with an extragonadal germ cell tumor. | Clinical medicine. Oncology 20080101 |
| Phase II Study of S-1 Monotherapy as a First-line, Combination Therapy of S-1 plus Cisplatin as a Second-line, and Weekly Paclitaxel Monotherapy as a Third-line Therapy in Patients with Advanced Gastric Carcinoma: Phase II Study of S-1, S-1 plus Cisplatin, and Weekly Paclitaxel in Patients with Advanced Gastric Carcinoma. | Clinical medicine. Oncology 20080101 |
| A Single Institution's Experience with Bevacizumab in Combination with Cytotoxic Chemotherapy in Progressive Malignant Glioma. | Clinical medicine. Oncology 20080101 |
| Docetaxel as salvage therapy in highly pretreated and drug resistant gastrointestinal carcinomas. | Clinical medicine. Oncology 20080101 |
| Chemotherapeutic treatment of priapism in metastatic rectal cancer. | Case reports in gastroenterology 20080101 |
| Institutional guidelines and ongoing studies in management of liver tumours: the experience of the European Institute of Oncology. | Ecancermedicalscience 20080101 |
| 2007 EORTC-NCI-ASCO annual meeting: molecular markers in cancer. | Ecancermedicalscience 20080101 |
| A randomised trial evaluating bevacizumab as adjuvant therapy following resection of AJCC stage IIB, IIC and III cutaneous melanoma: an update. | Ecancermedicalscience 20080101 |
| Irinotecan drug eluting beads used as a treatment of advanced intra hepatic cholangiocarcinoma. | Journal of radiology case reports 20080101 |
| The therapeutic potential of a series of orally bioavailable anti-angiogenic microtubule disruptors as therapy for hormone-independent prostate and breast cancers. | British journal of cancer 20071217 |
| A phase 1 study of fixed dose rate gemcitabine and irinotecan in patients with advanced pancreatic and biliary cancer. | Cancer 20071215 |
| Tumors established with cell lines selected for oxaliplatin resistance respond to oxaliplatin if combined with cetuximab. | Clinical cancer research : an official journal of the American Association for Cancer Research 20071215 |
| Bevacizumab plus infusional 5-fluorouracil, leucovorin and irinotecan for advanced colorectal cancer that progressed after oxaliplatin and irinotecan chemotherapy: a pilot study. | World journal of gastroenterology 20071214 |
| Capecitabine in combination with docetaxel and mitomycin C in patients with pre-treated tumours: results of an extended phase-I trial. | British journal of cancer 20071203 |
| Association of progression-free survival with patient-reported outcomes and survival: results from a randomised phase 3 trial of panitumumab. | British journal of cancer 20071203 |
| Phase II trial of irinotecan, cisplatin and mitomycin for relapsed small cell lung cancer. | International journal of cancer 20071201 |
| Combination chemotherapy with cisplatin, etoposide and irinotecan in patients with extensive small-cell lung cancer: A phase II study of the Hellenic Co-operative Oncology Group. | Lung cancer (Amsterdam, Netherlands) 20071201 |
| Tumour vascularization: sprouting angiogenesis and beyond. | Cancer metastasis reviews 20071201 |
| A randomized phase II trial evaluating safety and efficacy of an experimental chemotherapy regimen (irinotecan + oxaliplatin, IRINOX) and two standard arms (LV5 FU2 + irinotecan or LV5 FU2 + oxaliplatin) in first-line metastatic colorectal cancer: a study of the Digestive Group of the Fédération Nationale des Centres de Lutte Contre le Cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20071201 |
| A phase I and pharmacokinetic study of lapatinib in combination with infusional 5-fluorouracil, leucovorin and irinotecan. | Annals of oncology : official journal of the European Society for Medical Oncology 20071201 |
| Phase I trial of neoadjuvant preoperative chemotherapy with S-1 and irinotecan plus radiation in patients with locally advanced rectal cancer. | International journal of radiation oncology, biology, physics 20071201 |
| Characterization of the UDP glucuronosyltransferase activity of human liver microsomes genotyped for the UGT1A1*28 polymorphism. | Drug metabolism and disposition: the biological fate of chemicals 20071201 |
| Hepatic arterial infusion plus systemic irinotecan in patients with unresectable hepatic metastases from colorectal cancer previously treated with systemic oxaliplatin: a retrospective analysis. | Annals of oncology : official journal of the European Society for Medical Oncology 20071201 |
| Bringing unresectable liver disease to resection with curative intent. | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20071201 |
| A limited sampling strategy to estimate the pharmacokinetic parameters of irinotecan and its active metabolite, SN-38, in patients with metastatic digestive cancer receiving the FOLFIRI regimen. | Oncology reports 20071201 |
| Editorial: what is new in the treatment of gliomas? | Current opinion in neurology 20071201 |
| [Systemic treatment of peritoneal metastases]. | Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 20071201 |
| Treatment of advanced colorectal cancer in the elderly. | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20071201 |
| Possible delayed onset of osteonecrosis of the jaw in association with zoledronic acid. | Journal of clinical pharmacy and therapeutics 20071201 |
| Intensified irinotecan-based neoadjuvant chemoradiotherapy in rectal cancer: four consecutive designed studies to minimize acute toxicity and to optimize efficacy measured by pathologic complete response. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20071201 |
| AACR-NCI-EORTC--19th symposium. Molecular Targets and Cancer Therapeutics--Part 1. | IDrugs : the investigational drugs journal 20071201 |
| Chemotherapy induced diarrhea. | Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20071201 |
| Predictive molecular markers for colorectal cancer patients with resected liver metastasis and adjuvant chemotherapy. | Gastroenterology 20071201 |
| Phase I study of temozolomide and irinotecan for recurrent malignant gliomas in patients receiving enzyme-inducing antiepileptic drugs: a north american brain tumor consortium study. | Clinical cancer research : an official journal of the American Association for Cancer Research 20071201 |
| Nutritional modulation of antitumor efficacy and diarrhea toxicity related to irinotecan chemotherapy in rats bearing the ward colon tumor. | Clinical cancer research : an official journal of the American Association for Cancer Research 20071201 |
| Cetuximab in combination with 5-fluorouracil, leucovorin and irinotecan as a neoadjuvant chemotherapy in patients with initially unresectable colorectal liver metastases. | Onkologie 20071201 |
| [In these days molecule target drug in advanced non-small cell lung cancer]. | Kyobu geka. The Japanese journal of thoracic surgery 20071201 |
| Cryptogenic organizing pneumonitis during oxaliplatin chemotherapy for colorectal cancer: case report. | Chest 20071201 |
| Bi-weekly irinotecan hydrochloride and cisplatin as a second-line chemotherapy for patients with advanced gastric cancer. | Gan to kagaku ryoho. Cancer & chemotherapy 20071201 |
| [Clinical study of irinotecan plus infusional fluorouracil/l-leucovorin (FOLFIRI) in patients with fluoropyrimidine-resistant metastatic colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20071201 |
| [Two cases of stage IV gastric cancer who underwent total gastrectomy and achieved long-term survival by sequential chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20071201 |
| [A case report--combination chemotherapy with oral UFT and CPT-11, 5-FU, l-LV by hepatic arterial infusion for multiple hepatic metastasis from sigmoid colon cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20071201 |
| [A case undergoing repeated anaphylactic shock after systemic administration of vinorelbine]. | Gan to kagaku ryoho. Cancer & chemotherapy 20071201 |
| Broad funding for oxaliplatin in Ontario (finally!). | Current oncology (Toronto, Ont.) 20071201 |
| Inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation on tumor-associated endothelial cells leads to treatment of orthotopic human colon cancer in nude mice. | Neoplasia (New York, N.Y.) 20071201 |
| Clinicopathologic features and histochemical analyses of proliferative activity and angiogenesis in small cell carcinoma of the esophagus. | Journal of gastroenterology 20071201 |
| Novel E-ring camptothecin keto analogues (S38809 and S39625) are stable, potent, and selective topoisomerase I inhibitors without being substrates of drug efflux transporters. | Molecular cancer therapeutics 20071201 |
| [A case of relapsed small-cell lung cancer successfully treated by administration of amrubicin]. | Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20071201 |
| Current concepts in targeted therapies for the pathophysiology of diabetic microvascular complications. | Vascular health and risk management 20071201 |
| Phase II study of irinotecan plus leucovorin and bolus 5-fluorouracil as first- or second-line chemotherapy in patients with advanced gastric or esophageal-gastric junction adenocarcinoma. | Journal of chemotherapy (Florence, Italy) 20071201 |
| Retrospective comparison of two different schedules of irinotecan, 5-fluorouracil and folinic acid in previously untreated patients with advanced colorectal carcinoma: a single institution experience. | Journal of chemotherapy (Florence, Italy) 20071201 |
| Experimental evidence for the efficacy of combined therapy of CPT-11 and hyperthermia for squamous cell carcinoma of the esophagus. | Hepato-gastroenterology 20071201 |
| Update on clinical data combining capecitabine with targeted agents in newly diagnosed colorectal cancer. | Clinical colorectal cancer 20071201 |
| Update on clinical data with regimens inhibiting angiogenesis and epidermal growth factor receptor for patients with newly diagnosed metastatic colorectal cancer. | Clinical colorectal cancer 20071201 |
| Exploring alternative individualized treatment strategies in colorectal cancer. | Clinical colorectal cancer 20071201 |
| A retrospective on the inhibition of epidermal growth factor receptor as a therapeutic strategy for patients with relapsed metastatic colorectal cancer: impact on treatment of today's patients. | Clinical colorectal cancer 20071201 |
| Metronomic chemotherapy using weekly low-dosage CPT-11 and UFT as postoperative adjuvant therapy in colorectal cancer at high risk to recurrence. | Journal of experimental & clinical cancer research : CR 20071201 |
| Mechanisms of toxicity of 3-alkylpyridinium polymers from marine sponge Reniera sarai. | Marine drugs 20071201 |
| [Polymorphisms of UGT1A gene and irinotecan toxicity in Chinese colorectal cancer patients]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20071201 |
| Palonosetron as an anti-emetic and anti-nausea agent in oncology. | Therapeutics and clinical risk management 20071201 |
| Drug-eluting particles for interventional pharmacology. | Techniques in vascular and interventional radiology 20071201 |
| Review of erlotinib in the treatment of advanced non-small cell lung cancer. | Biologics : targets & therapy 20071201 |
| Update on the treatment of cutaneous T-cell lymphoma (CTCL): Focus on vorinostat. | Biologics : targets & therapy 20071201 |
| New approaches in angiogenic targeting for colorectal cancer. | World journal of gastroenterology 20071128 |
| Combining chemotherapy and targeted therapies in metastatic colorectal cancer. | World journal of gastroenterology 20071128 |
| Epidermal growth factor receptor inhibitors in colorectal cancer treatment: what's new? | World journal of gastroenterology 20071128 |
| Progression-free survival is a surrogate for survival in advanced colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071120 |
| Preoperative radiotherapy combined with 5 days per week capecitabine chemotherapy in locally advanced rectal cancer. | British journal of cancer 20071119 |
| Cetuximab for the treatment of colorectal cancer. | The New England journal of medicine 20071115 |
| New approaches to assessing and treating early-stage colon and rectal cancers: cooperative group strategies for assessing optimal approaches in early-stage disease. | Clinical cancer research : an official journal of the American Association for Cancer Research 20071115 |
| Spinocerebellar ataxia with axonal neuropathy: consequence of a Tdp1 recessive neomorphic mutation? | The EMBO journal 20071114 |
| [Long- term remission survival with a case of rectal carcinoid tumor with metastasis in the soft tissue effectively treated with the combination therapy of irinotecan/5-fluorouracil/levofolinate followed by resection]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20071110 |
| Long-term survival in a patient with acinar cell carcinoma of pancreas. A case report and review of literature. | JOP : Journal of the pancreas 20071109 |
| In silico and in vitro pharmacogenetic analysis in mice. | Proceedings of the National Academy of Sciences of the United States of America 20071106 |
| A phase I study of bi-weekly administration of 24-h gemcitabine followed by 24-h irinotecan in patients with solid tumors. | Cancer chemotherapy and pharmacology 20071101 |
| Phase II study of weekly irinotecan and cisplatin for refractory or recurrent non-small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20071101 |
| Capecitabine plus oxaliplatin and irinotecan regimen every other week: a phase I/II study in first-line treatment of metastatic colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20071101 |
| Systemic chemotherapy and two-stage hepatectomy for extensive bilateral colorectal liver metastases: perioperative safety and survival. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20071101 |
| Medical treatment for advanced gastroesophageal adenocarcinoma. | Current opinion in gastroenterology 20071101 |
| The cost-effectiveness of bevacizumab in the first-line treatment of metastatic colorectal cancer in England and Wales. | European journal of cancer (Oxford, England : 1990) 20071101 |
| Chemopreventive effects of Panax notoginseng and its major constituents on SW480 human colorectal cancer cells. | International journal of oncology 20071101 |
| Investigation of two dosing schedules of vandetanib (ZD6474), an inhibitor of vascular endothelial growth factor receptor and epidermal growth factor receptor signaling, in combination with irinotecan in a human colon cancer xenograft model. | Clinical cancer research : an official journal of the American Association for Cancer Research 20071101 |
| A randomized, phase II trial of two dose levels of temsirolimus (CCI-779) in patients with extensive-stage small-cell lung cancer who have responding or stable disease after induction chemotherapy: a trial of the Eastern Cooperative Oncology Group (E1500). | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20071101 |
| [Results of chemotherapy using new anti-cancer drugs since S-1 for advanced or recurrent gastric cancer in our institute]. | Gan to kagaku ryoho. Cancer & chemotherapy 20071101 |
| [A case of cytology-positive, stage IV gastric cancer, alive with no recurrence for 4 years, curatively treated with combination chemotherapy using S-1, CPT-11 and subsequent total gastrectomy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20071101 |
| [A patient with recurrent rectal cancer in whom pulmonary metastasis disappeared by FOLFOX 4 therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20071101 |
| Synthesis and structure-activity relationships of potent antitumor active quinoline and naphthyridine derivatives. | Anti-cancer agents in medicinal chemistry 20071101 |
| Successful desensitization protocol for hypersensitivity reactions caused by oxaliplatin. | International journal of clinical pharmacology and therapeutics 20071101 |
| Cetuximab efficacy in patients treated routinely in university hospitals. | Gastroenterologie clinique et biologique 20071101 |
| Phase II study of cisplatin combined to irinotecan administered alternatingly with docetaxel in advanced non-small cell lung cancer. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20071101 |
| [A long-term surviving patient with unresectable lung metastasis from colon cancer treated with intravenous administration of activated autologous lymphocytes and low-dose chemotherapy--a case report]. | Gan to kagaku ryoho. Cancer & chemotherapy 20071101 |
| [Transarterial chemoembolization with irinotecan (CPT-11) and degradable starch microspheres (DSM) in patients with liver metastases from colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20071101 |
| [An elderly patient with recurrent rectal cancer successfully responded to S-1 combined with CPT-11]. | Gan to kagaku ryoho. Cancer & chemotherapy 20071101 |
| [A case of multiple liver metastases from rectal cancer in poor performance status successfully treated with hepatic arterial infusion chemotherapy plus CPT-11]. | Gan to kagaku ryoho. Cancer & chemotherapy 20071101 |
| [Evaluation of bronchial arterial infusion (BAI) for lung cancer with carcinomatous pleuritis]. | Gan to kagaku ryoho. Cancer & chemotherapy 20071101 |
| [Carboplatin and CPT-11 chemotherapy in a hemodialysis patient with small-cell lung cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20071101 |
| [Three successful cases with CPT-11 + CDDP chemotherapy where S-1 failed to respond to recurrent gastric cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20071101 |
| [A case of unresectable gastric cancer successfully treated with combination chemotherapy of S-1 + CPT-11]. | Gan to kagaku ryoho. Cancer & chemotherapy 20071101 |
| [A case of S-1 resistant multiple lung metastases after curative total gastrectomy for gastric cancer successfully treated by S-1 combined with CPT-11 as the third-line chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20071101 |
| [Prediction of adverse drug reactions based on genomic information]. | Nihon rinsho. Japanese journal of clinical medicine 20071028 |
| Lactobacillus supplementation for diarrhoea related to chemotherapy of colorectal cancer: a randomised study. | British journal of cancer 20071022 |
| Final analysis of colorectal cancer patients treated with irinotecan and 5-fluorouracil plus folinic acid neoadjuvant chemotherapy for unresectable liver metastases. | British journal of cancer 20071022 |
| PTEN loss of expression predicts cetuximab efficacy in metastatic colorectal cancer patients. | British journal of cancer 20071022 |
| Taming glioblastoma: targeting angiogenesis. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071020 |
| Evaluation of alternate size descriptors for dose calculation of anticancer drugs in the obese. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071020 |
| Predicting treatment response of malignant gliomas to bevacizumab and irinotecan by imaging proliferation with [18F] fluorothymidine positron emission tomography: a pilot study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071020 |
| Bevacizumab plus irinotecan in recurrent glioblastoma multiforme. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071020 |
| Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: results from the BICC-C Study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071020 |
| Gene expression analysis of multiple gastrointestinal regions reveals activation of common cell regulatory pathways following cytotoxic chemotherapy. | International journal of cancer 20071015 |
| The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas. | Cancer research 20071015 |
| Randomized phase II trial of cetuximab, bevacizumab, and irinotecan compared with cetuximab and bevacizumab alone in irinotecan-refractory colorectal cancer: the BOND-2 study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071010 |
| Hepatic resection after rescue cetuximab treatment for colorectal liver metastases previously refractory to conventional systemic therapy. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071010 |
| Phase II trial of irinotecan in children with refractory solid tumors: a Children's Oncology Group Study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071010 |
| Phase I study of S-1, docetaxel and cisplatin combination chemotherapy in patients with unresectable metastatic gastric cancer. | British journal of cancer 20071008 |
| First-into-man phase I and pharmacokinetic study of XR5944.14, a novel agent with a unique mechanism of action. | British journal of cancer 20071008 |
| Carcinoma of an unknown primary: are EGF receptor, Her-2/neu, and c-Kit tyrosine kinases potential targets for therapy? | British journal of cancer 20071008 |
| Intra-ethnic differences in genetic variants of the UGT-glucuronosyltransferase 1A1 gene in Chinese populations. | The pharmacogenomics journal 20071001 |
| Phase I study of gefitinib, irinotecan, 5-fluorouracil and leucovorin in patients with metastatic colorectal cancer. | Cancer chemotherapy and pharmacology 20071001 |
| Short hairpin RNAs targeting Bcl-xL modulate senescence and apoptosis following SN-38 and irinotecan exposure in a colon cancer model. | Cancer chemotherapy and pharmacology 20071001 |
| MEK activation suppresses CPT11-induced apoptosis in rat intestinal epithelial cells through a COX-2-dependent mechanism. | Digestive diseases and sciences 20071001 |
| Isolated metastasis of lung cancer to the thyroid gland. | Lung cancer (Amsterdam, Netherlands) 20071001 |
| Expression and characterization of a human carboxylesterase 2 splice variant. | The Journal of pharmacology and experimental therapeutics 20071001 |
| Haplotypes and a novel defective allele of CES2 found in a Japanese population. | Drug metabolism and disposition: the biological fate of chemicals 20071001 |
| Convection-enhanced delivery of nanoliposomal CPT-11 (irinotecan) and PEGylated liposomal doxorubicin (Doxil) in rodent intracranial brain tumor xenografts. | Neuro-oncology 20071001 |
| Preoperative chemoradiotherapy with capecitabine and oxaliplatin in locally advanced rectal cancer. A phase I-II multicenter study of the Dutch Colorectal Cancer Group. | Annals of surgical oncology 20071001 |
| Acute toxicity of irinotecan in the ex-vivo isolated perfused human lung model--high-dose therapy during isolated perfusion without acute toxic lung edema. | Interactive cardiovascular and thoracic surgery 20071001 |
| Effect of betulinic acid on anticancer drug-resistant colon cancer cells. | Basic & clinical pharmacology & toxicology 20071001 |
| Survival and disease-progression benefits with treatment regimens for advanced colorectal cancer: a meta-analysis. | The Lancet. Oncology 20071001 |
| Effective second-line treatment with cetuximab and bevacizumab in a patient with hepatic metastases of colorectal cancer and hyperbilirubinemia. | Onkologie 20071001 |
| Severe toxicities after irinotecan-based chemotherapy in a patient with lung cancer: a homozygote for the SLCO1B1*15 allele. | Therapeutic drug monitoring 20071001 |
| Irinotecan-cisplatin therapy for patients with extensive-stage small cell lung cancer: use patterns among American medical oncologists 2000-2006. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20071001 |
| The therapeutic potential of O6-alkylguanine DNA alkyltransferase inhibitors. | Expert opinion on investigational drugs 20071001 |
| A phase II study of irinotecan with bi-weekly, low-dose leucovorin and bolus and continuous infusion 5-fluorouracil (modified FOLFIRI) as salvage therapy for patients with advanced or metastatic gastric cancer. | Japanese journal of clinical oncology 20071001 |
| [A case of unresectable gastric cancer complicated by serious pyloric stenosis in which S-1 administration after gastrojejunostomy proved effective]. | Gan to kagaku ryoho. Cancer & chemotherapy 20071001 |
| [A case of metastatic rectal cancer showing a sustained complete response to chemotherapy with FOLFIRI followed by UFT]. | Gan to kagaku ryoho. Cancer & chemotherapy 20071001 |
| [Neoadjuvant chemotherapy with combination of S-1 and CPT-11 in advanced rectal cancer - a case report]. | Gan to kagaku ryoho. Cancer & chemotherapy 20071001 |
| A reliable tool to determine cell viability in complex 3-d culture: the acid phosphatase assay. | Journal of biomolecular screening 20071001 |
| Case of rectal malignant melanoma showing immunohistochemical variability in a tumor. | Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20071001 |
| Adjuvant therapy for colon cancer. | Current gastroenterology reports 20071001 |
| Optimizing administration of epidermal growth factor receptor-targeted agents in the treatment of colorectal cancer. | Clinical colorectal cancer 20071001 |
| FOLFIRI chemotherapy for metastatic colorectal cancer patients. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20071001 |
| Comparative cytotoxicity of C-1311 in colon cancer in vitro and in vivo using the hollow fiber assay. | Journal of chemotherapy (Florence, Italy) 20071001 |
| Phase II trial of a biweekly regimen of fluorouracil and leucovorin plus irinotecan in patients with previously untreated advanced gastric cancer. | Journal of chemotherapy (Florence, Italy) 20071001 |
| The impact of the introduction of irinotecan and oxaliplatin on the outcome of patients with advanced colorectal cancer. | Journal of chemotherapy (Florence, Italy) 20071001 |
| Local-regional approach to diffuse malignant peritoneal mesothelioma. | Gastroenterologie clinique et biologique 20071001 |
| Malignant peritoneal mesothelioma: treatment with maximal cytoreductive surgery plus intraperitoneal chemotherapy. | Gastroenterologie clinique et biologique 20071001 |
| Current options for the management of rectal cancer. | Current treatment options in oncology 20071001 |
| Interstitial chemotherapy with biodegradable BCNU (Gliadel) wafers in the treatment of malignant gliomas. | Therapeutics and clinical risk management 20071001 |
| Targeting methylguanine-DNA methyltransferase in the treatment of neuroblastoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070915 |
| Combination treatment with TRA-8 anti death receptor 5 antibody and CPT-11 induces tumor regression in an orthotopic model of pancreatic cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070915 |
| Modulatory effects of heparin and short-length oligosaccharides of heparin on the metastasis and growth of LMD MDA-MB 231 breast cancer cells in vivo. | British journal of cancer 20070911 |
| UGT1A1*28 genotype and irinotecan-induced neutropenia: dose matters. | Journal of the National Cancer Institute 20070905 |
| Genetic linkage of UGT1A7 and UGT1A9 polymorphisms to UGT1A1*6 is associated with reduced activity for SN-38 in Japanese patients with cancer. | Cancer chemotherapy and pharmacology 20070901 |
| Interleukin-6 alters the cellular responsiveness to clopidogrel, irinotecan, and oseltamivir by suppressing the expression of carboxylesterases HCE1 and HCE2. | Molecular pharmacology 20070901 |
| Involvement of up-regulation of hepatic breast cancer resistance protein in decreased plasma concentration of 7-ethyl-10-hydroxycamptothecin (SN-38) by coadministration of S-1 in rats. | Drug metabolism and disposition: the biological fate of chemicals 20070901 |
| [Role of pharmacogenetics in chemotherapy of colorectal cancers]. | La Revue de medecine interne 20070901 |
| Role of UGT1A1*6, UGT1A1*28 and ABCG2 c.421C>A polymorphisms in irinotecan-induced neutropenia in Asian cancer patients. | Cancer science 20070901 |
| A phase II study of irinotecan, high-dose 24-h continuous intravenous infusion of floxuridine and leucovorin (IFLUX) for advanced, previously untreated colorectal cancer. | Anti-cancer drugs 20070901 |
| Irinotecan-based chemotherapy in a metastatic colorectal cancer patient under haemodialysis for chronic renal dysfunction: two cases considered. | Anti-cancer drugs 20070901 |
| Putative chemosensitivity predictive genes in colorectal cancer cell lines for anticancer agents. | Oncology reports 20070901 |
| Panitumumab monotherapy in patients with previously treated metastatic colorectal cancer. | Cancer 20070901 |
| Economic analysis of a multicentre, randomised, phase III trial comparing FOLFOXIRI with FOLFIRI in patients with metastatic colorectal cancer in Greece. | Current medical research and opinion 20070901 |
| Efficacy and safety of an irinotecan plus bolus 5-fluorouracil and L-leucovorin regimen for metastatic colorectal cancer in Japanese patients: experience in a single institution in Japan. | Japanese journal of clinical oncology 20070901 |
| 5T4-modified vaccinia ankara: progress in tumor-associated antigen-based immunotherapy. | Expert opinion on biological therapy 20070901 |
| Eye complications of cetuximab therapy. | European journal of cancer care 20070901 |
| Nuclear factor-kB tumor expression predicts response and survival in irinotecan-refractory metastatic colorectal cancer treated with cetuximab-irinotecan therapy. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070901 |
| Sequential chemotherapy with combination irinotecan and cisplatin followed by docetaxel for treatment-naïve patients with advanced non-small cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20070901 |
| Third-generation chemotherapy agents in the treatment of advanced non-small cell lung cancer: a meta-analysis. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20070901 |
| Irinotecan, carboplatin, and imatinib in untreated extensive-stage small-cell lung cancer: a phase II trial of the Minnie Pearl Cancer Research Network. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20070901 |
| Development and characterization of a model of liver metastasis using human colon cancer HCT-116 cells. | Biological & pharmaceutical bulletin 20070901 |
| Irinotecan chemotherapy during valproic acid treatment: pharmacokinetic interaction and hepatotoxicity. | Cancer biology & therapy 20070901 |
| [A case of advanced gastric cancer responding remarkably to neo-adjuvant combination chemotherapy using CPT-11 plus S-1]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070901 |
| VSL#3 probiotic treatment reduces chemotherapy-induced diarrhea and weight loss. | Cancer biology & therapy 20070901 |
| Oncologists' current opinion on the treatment of colon carcinoma. | Anti-cancer agents in medicinal chemistry 20070901 |
| Small cell lung cancer: have we made any progress over the last 25 years? | The oncologist 20070901 |
| Molecular markers in colorectal cancer: genetic bases for a customised treatment. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20070901 |
| Safety of irinotecan/cisplatin versus etoposide/cisplatin for patients with extensive-stage small-cell lung cancer: a metaanalysis. | Clinical lung cancer 20070901 |
| A Phase II study of cetuximab (Erbitux) plus FOLFIRI for irinotecan and oxaliplatin-refractory metastatic colorectal cancer. | Journal of Korean medical science 20070901 |
| Combined-modality therapy for rectal cancer: future prospects. | Clinical colorectal cancer 20070901 |
| Oxaliplatin and fixed-rate infusional gemcitabine in the second-line treatment of patients with metastatic colon cancer: final results of a Phase II trial prematurely closed as a result of poor accrual. | Clinical colorectal cancer 20070901 |
| Metachronous metastasis to the penis from a rectal adenocarcinoma. | Clinical colorectal cancer 20070901 |
| Translation of pharmacogenetic knowledge into cancer therapeutics. | Clinical advances in hematology & oncology : H&O 20070901 |
| Intravitreal bevacizumab: an analysis of the evidence. | Clinical ophthalmology (Auckland, N.Z.) 20070901 |
| Targeted therapy of advanced non-small cell lung cancer: the role of bevacizumab. | Biologics : targets & therapy 20070901 |
| Irinotecan, docetaxel and oxaliplatin combination in metastatic gastric or gastroesophageal junction adenocarcinoma. | British journal of cancer 20070828 |
| Intratumoural injection of the toll-like receptor-2/6 agonist 'macrophage-activating lipopeptide-2' in patients with pancreatic carcinoma: a phase I/II trial. | British journal of cancer 20070828 |
| 2,2,2-Trichloro-N-({2-[2-(dimethylamino)ethyl]-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin- 5-yl}carbamoyl)acetamide (UNBS3157), a novel nonhematotoxic naphthalimide derivative with potent antitumor activity. | Journal of medicinal chemistry 20070823 |
| A phase II study of S-1 monotherapy administered for 2 weeks of a 3-week cycle in advanced gastric cancer patients with poor performance status. | British journal of cancer 20070820 |
| Combined evaluation of Rad51 and ERCC1 expressions for sensitivity to platinum agents in non-small cell lung cancer. | International journal of cancer 20070815 |
| A renewed call for equipoise. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070810 |
| Irinotecan fluorouracil plus leucovorin is not superior to fluorouracil plus leucovorin alone as adjuvant treatment for stage III colon cancer: results of CALGB 89803. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070810 |
| Impact of complete response to chemotherapy on overall survival in advanced colorectal cancer: results from Intergroup N9741. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070810 |
| Vinorelbine/carboplatin vs gemcitabine/carboplatin in advanced NSCLC shows similar efficacy, but different impact of toxicity. | British journal of cancer 20070806 |
| Prognostic analysis of tumour angiogenesis, determined by microvessel density and expression of vascular endothelial growth factor, in high-risk primary breast cancer patients treated with high-dose chemotherapy. | British journal of cancer 20070806 |
| Combined modalities of resistance in an oxaliplatin-resistant human gastric cancer cell line with enhanced sensitivity to 5-fluorouracil. | British journal of cancer 20070806 |
| GAMEC--a new intensive protocol for untreated poor prognosis and relapsed or refractory germ cell tumours. | British journal of cancer 20070806 |
| Phase II study of UFT with leucovorin and irinotecan (TEGAFIRI): first-line therapy for metastatic colorectal cancer. | British journal of cancer 20070806 |
| Multicentre phase II study using increasing doses of irinotecan combined with a simplified LV5FU2 regimen in metastatic colorectal cancer. | Cancer chemotherapy and pharmacology 20070801 |
| A phase II study of irinotecan (CPT-11) and carboplatin in patients with limited disease small cell lung cancer (SCLC). | Lung cancer (Amsterdam, Netherlands) 20070801 |
| Novel stable camptothecin derivatives replacing the E-ring lactone by a ketone function are potent inhibitors of topoisomerase I and promising antitumor drugs. | Molecular pharmacology 20070801 |
| Pilot study evaluating the efficacy and toxicity of irinotecan plus oral etoposide for platinum- and taxane-resistant epithelial ovarian cancer. | Gynecologic oncology 20070801 |
| Updated efficacy and toxicity analysis of irinotecan and oxaliplatin (IROX) : intergroup trial N9741 in first-line treatment of metastatic colorectal cancer. | Cancer 20070801 |
| EGFR-targeted therapies in colorectal cancer. | Diseases of the colon and rectum 20070801 |
| Irinotecan and cisplatin with concurrent split-course radiotherapy in locally advanced nonsmall-cell lung cancer: a multiinstitutional phase 2 study. | Cancer 20070801 |
| Combined paclitaxel and cetuximab achieved a major response on the skin metastases of a patient with epidermal growth factor receptor-positive, estrogen receptor-negative, progesterone receptor-negative and human epidermal growth factor receptor-2-negative (triple-negative) breast cancer. | Anti-cancer drugs 20070801 |
| Reintroduction of oxaliplatin is associated with improved survival in advanced colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070801 |
| Irinotecan-induced apoptosis is inhibited by increased P-glycoprotein expression and decreased p53 in human hepatocellular carcinoma cells. | Biological & pharmaceutical bulletin 20070801 |
| [A case of small cell carcinoma of the esophagus with remarkable response to chemotherapy with CPT-11 and CDDP]. | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20070801 |
| [Bevacizumab (Avastin)]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070801 |
| [Cetuximab]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070801 |
| [Neuroendocrine carcinoma of the prostate effectively treated by cisplatin and irinotecan--a case report]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070801 |
| Pharmacogenomics in drug-metabolizing enzymes catalyzing anticancer drugs for personalized cancer chemotherapy. | Current drug metabolism 20070801 |
| Camptothecin: therapeutic potential and biotechnology. | Current pharmaceutical biotechnology 20070801 |
| Translating pharmacogenomics: challenges on the road to the clinic. | PLoS medicine 20070801 |
| [Efficacy of CPT-11 combined 5-FU/CF (FOLFIRI) regimen on advanced colorectal cancer]. | Ai zheng = Aizheng = Chinese journal of cancer 20070801 |
| AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action in vivo, pharmacokinetic/pharmacodynamic relationship, and potential for combination in preclinical models. | Molecular cancer therapeutics 20070801 |
| The selective poly(ADP-ribose) polymerase-1(2) inhibitor, CEP-8983, increases the sensitivity of chemoresistant tumor cells to temozolomide and irinotecan but does not potentiate myelotoxicity. | Molecular cancer therapeutics 20070801 |
| Progression-free survival and overall survival of patients with clear cell carcinoma of the ovary treated with paclitaxel-carboplatin or irinotecan-cisplatin: retrospective analysis. | International journal of clinical oncology 20070801 |
| A patient with gastric cancer and liver metastases successfully treated with combination chemotherapy including S-1. | International journal of clinical oncology 20070801 |
| Continuous hyperthermic peritoneal perfusion for desmoplastic small round cell tumor. | Journal of pediatric surgery 20070801 |
| Identification of drugs that interact with herbs in drug development. | Drug discovery today 20070801 |
| Epidemiology, disease progression, and economic burden of colorectal cancer. | Journal of managed care pharmacy : JMCP 20070801 |
| Capecitabine plus 3-weekly irinotecan (XELIRI regimen) as first-line chemotherapy for metastatic colorectal cancer: phase II trial results. | American journal of clinical oncology 20070801 |
| Phase II study of paclitaxel and irinotecan chemotherapy in patients with advanced nonsmall cell lung cancer. | American journal of clinical oncology 20070801 |
| Optical imaging of tumor cells in hollow fibers: evaluation of the antitumor activities of anticancer drugs and target validation. | Neoplasia (New York, N.Y.) 20070801 |
| Optimizing combination chemotherapy by controlling drug ratios. | Molecular interventions 20070801 |
| [Chemotherapy in lung cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070801 |
| Therapy of colon carcinoma: an oncology perspective. Interview with Piotr M. Czaykowski by Paul C. Adams. | Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20070801 |
| New medical options for liver tumours. | Clinical medicine (London, England) 20070801 |
| Targeted therapy in rectal cancer. | Oncology (Williston Park, N.Y.) 20070801 |
| Randomised phase III trial of carboplatin plus etoposide vs split doses of cisplatin plus etoposide in elderly or poor-risk patients with extensive disease small-cell lung cancer: JCOG 9702. | British journal of cancer 20070716 |
| Pharmacogenomics of gemcitabine: can genetic studies lead to tailor-made therapy? | British journal of cancer 20070716 |
| TIMP-1 is significantly associated with objective response and survival in metastatic colorectal cancer patients receiving combination of irinotecan, 5-fluorouracil, and folinic acid. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070715 |
| Single agent fluorouracil for first-line treatment of advanced colorectal cancer as standard? | Lancet (London, England) 20070714 |
| Sequential versus combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (CAIRO): a phase III randomised controlled trial. | Lancet (London, England) 20070714 |
| Different strategies of sequential and combination chemotherapy for patients with poor prognosis advanced colorectal cancer (MRC FOCUS): a randomised controlled trial. | Lancet (London, England) 20070714 |
| Pancreatic cancer: is this bleak landscape finally changing? Highlights from the '43rd ASCO Annual Meeting'. Chicago, IL, USA. June 1-5, 2007. | JOP : Journal of the pancreas 20070709 |
| A dose escalation and pharmacokinetic study of biweekly pegylated liposomal doxorubicin, paclitaxel and gemcitabine in patients with advanced solid tumours. | British journal of cancer 20070702 |
| Epidermal growth factor receptor (EGFR) downstream signalling pathway in primary colorectal tumours and related metastatic sites: optimising EGFR-targeted treatment options. | British journal of cancer 20070702 |
| Dual inhibition of EGFR and VEGFR pathways in combination with irradiation: antitumour supra-additive effects on human head and neck cancer xenografts. | British journal of cancer 20070702 |
| The role of chemotherapy in microsatellite unstable (MSI-H) colorectal cancer. | International journal of colorectal disease 20070701 |
| Phase II study of biweekly administration of docetaxel and irinotecan in patients with refractory or relapsed advanced non-small cell lung cancer. | Cancer chemotherapy and pharmacology 20070701 |
| Preoperative chemotherapy for colorectal liver metastases: impact on hepatic histology and postoperative outcome. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20070701 |
| Associations of ABCB1, ABCC2, and ABCG2 polymorphisms with irinotecan-pharmacokinetics and clinical outcome in patients with advanced non-small cell lung cancer. | Cancer 20070701 |
| Sensitivity to CPT-11 and platinum derivatives of stage I/II node-negative breast, lung, and gastric cancer with occult neoplastic cells in lymph node sinuses. | Oncology reports 20070701 |
| Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A1*6 and *28. | Pharmacogenetics and genomics 20070701 |
| Cigarette smoking and the personalization of irinotecan therapy. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070701 |
| Cigarette smoking and irinotecan treatment: pharmacokinetic interaction and effects on neutropenia. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070701 |
| Irinotecan activates p53 with its active metabolite, resulting in human hepatocellular carcinoma apoptosis. | Journal of pharmacological sciences 20070701 |
| Radiotherapy for localized rectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20070701 |
| [Therapeutic strategy for type 4 gastric cancer from the clinical oncologist standpoint]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070701 |
| Oxaliplatin plus 5-fluorouracil/leucovorin (FOLFOX-4) as salvage chemotherapy in patients with pretreated colorectal cancer. | Gan to kagaku ryoho. Cancer & chemotherapy 20070701 |
| [Irinotecan+cisplatin and irradiation are effective for brain metastases of gastric cancer--two case reports]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070701 |
| [Complete remission of hepatic metastasis of gastric cancer with CPT-11]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070701 |
| Management of gastric adenocarcinoma. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20070701 |
| Low dose gemcitabine plus cisplatin in a weekly-based regimen as salvage therapy for relapsed breast cancer after taxane-anthracycline-containing regimens. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20070701 |
| Effect of platinum combined with irinotecan or paclitaxel against large cell neuroendocrine carcinoma of the lung. | Japanese journal of clinical oncology 20070701 |
| Capecitabine and irinotecan in advanced gastric cancer. | The Lancet. Oncology 20070701 |
| Hepatic arterial infusion of oxaliplatin for a patient with hepatic metastases from colon cancer undergoing hemodialysis. | Japanese journal of clinical oncology 20070701 |
| Increased frequency of uridine diphosphate glucuronosyltransferase 1A1 7/7 in patients experiencing severe irinotecan-induced toxicities. | Clinical colorectal cancer 20070701 |
| Phase I/II study of CPT-11 plus UFT in patients with advanced/recurrent colorectal cancer: Osaka Gastrointestinal Cancer Chemotherapy Study Group (OGSG): Protocol 0102. | Japanese journal of clinical oncology 20070701 |
| Distribution of the UGT1A1*28 polymorphism in Caucasian and Asian populations in the US: a genomic analysis of 138 healthy individuals. | Anti-cancer drugs 20070701 |
| UFT/leucovorin and mitomycin C as salvage treatment in patients with advanced colorectal cancer - a retrospective analysis. | Anti-cancer drugs 20070701 |
| [Anti-angiogenic treatment and colorectal cancer]. | Bulletin du cancer 20070701 |
| Hydroxycamptothecin deactivation rates and binding to model membranes and HSA determined by fluorescence spectra analysis. | Combinatorial chemistry & high throughput screening 20070701 |
| C421 allele-specific ABCG2 gene amplification confers resistance to the antitumor triazoloacridone C-1305 in human lung cancer cells. | Biochemical pharmacology 20070630 |
| UGT1A1 promoter genotype correlates with SN-38 pharmacokinetics, but not severe toxicity in patients receiving low-dose irinotecan. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070620 |
| Mechanisms of adverse effects of anti-VEGF therapy for cancer. | British journal of cancer 20070618 |
| Combined modality chemoradiation in elderly oesophageal cancer patients. | British journal of cancer 20070618 |
| Synthesis and topoisomerase poisoning activity of A-ring and E-ring substituted luotonin A derivatives. | Bioorganic & medicinal chemistry 20070615 |
| Role of copper gluconate/triethanolamine in irinotecan encapsulation inside the liposomes. | International journal of pharmaceutics 20070607 |
| Effect of pH and human serum albumin on the cytotoxicity of a glucuronide prodrug of 9-aminocamptothecin. | Cancer chemotherapy and pharmacology 20070601 |
| Irinotecan-cisplatin interactions assessed in cell-based screening assays: cytotoxicity, drug accumulation and DNA adduct formation in an NSCLC cell line. | Cancer chemotherapy and pharmacology 20070601 |
| A phase I study of oral LY293111 given daily in combination with irinotecan in patients with solid tumours. | Investigational new drugs 20070601 |
| Pharmacokinetic and safety study of weekly irinotecan and oral capecitabine in patients with advanced solid cancers. | Investigational new drugs 20070601 |
| Optimization of hyperthermic intraperitoneal chemotherapy with oxaliplatin plus irinotecan at 43 degrees C after compete cytoreductive surgery: mortality and morbidity in 106 consecutive patients. | Annals of surgical oncology 20070601 |
| Chemotherapy of advanced gastric cancer. | Cancer treatment reviews 20070601 |
| A phase II trial of cisplatin and irinotecan alternating with doxorubicin, cyclophosphamide and etoposide in previously untreated patients with extensive-disease small-cell lung cancer. | Cancer chemotherapy and pharmacology 20070601 |
| Enhanced antitumor activity of irinotecan combined with propolis and its polyphenolic compounds on Ehrlich ascites tumor in mice. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20070601 |
| Phase I/II study of irinotecan (CPT-11) and S-1 in the treatment of advanced gastric cancer. | Anti-cancer drugs 20070601 |
| Therapeutic potential of the dual-targeted TAS-102 formulation in the treatment of gastrointestinal malignancies. | Cancer science 20070601 |
| DNA topoisomerase inhibitor, etoposide, enhances GC-box-dependent promoter activity via Sp1 phosphorylation. | Cancer science 20070601 |
| Comparison of three methods for genotyping the UGT1A1 (TA)n repeat polymorphism. | Clinical biochemistry 20070601 |
| The interactive transcript abundance index [c-myc*p73alpha]/[p21*Bcl-2] correlates with baseline level of apoptosis and response to CPT-11 in human bronchogenic carcinoma cell lines. | International journal of oncology 20070601 |
| UGT1A1 polymorphism can predict hematologic toxicity in patients treated with irinotecan. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070601 |
| Irinotecan toxicity to human blood cells in vitro: relationship between various biomarkers. | Basic & clinical pharmacology & toxicology 20070601 |
| Insights, challenges, and future directions in irinogenetics. | Therapeutic drug monitoring 20070601 |
| Gemcitabine and irinotecan for patients with untreated extensive stage small cell lung cancer: SWOG 0119. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20070601 |
| Irinotecan with 5-FU/FA in advanced biliary tract adenocarcinomas: a multicenter phase II trial. | American journal of clinical oncology 20070601 |
| A systematic review of economic analyses of pharmaceutical therapies for advanced colorectal cancer. | Expert opinion on pharmacotherapy 20070601 |
| [Second-line chemotherapy in gastric cancer following S-1 with CPT-11 chemotherapy performed as clinical trial]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070601 |
| [Evaluation of combination chemotherapy with 5-FU, CDDP and CPT-11 for human gastric carcinoma transplanted into nude mice - comparative study of in vivo chemosensitivity test]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070601 |
| [A case of unresectable advanced pancreatic cancer treated by S-1 with concurrent radiotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070601 |
| [Long survival of a colon cancer case with multiple liver metastases cured by multidisciplinary therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070601 |
| Serum amylase is a sensitive tumor marker for amylase-producing small cell lung cancer? | International journal of clinical oncology 20070601 |
| Role of repeated hepatectomy in the multimodal treatment of hepatic colorectal metastases. | Archives of surgery (Chicago, Ill. : 1960) 20070601 |
| Paclitaxel, ifosfamide, and nedaplatin (TIN) salvage chemotherapy for patients with advanced germ cell tumors. | International journal of urology : official journal of the Japanese Urological Association 20070601 |
| Canadian recommendations for the treatment of glioblastoma multiforme. | Current oncology (Toronto, Ont.) 20070601 |
| Outpatient-basis chemotherapy of oxaliplatin, 5-fluorouracil, and leucovorin as first-line treatment for patients with metastatic or recurrent colorectal cancer. | Journal of Korean medical science 20070601 |
| UGT1AI*6 and UGT1A1*27 for individualized irinotecan chemotherapy. | Current opinion in molecular therapeutics 20070601 |
| Hand-foot syndrome with scleroderma-like change induced by the oral capecitabine: a case report. | The Korean journal of internal medicine 20070601 |
| Chemotherapy-induced mucositis: focusing on diarrhea. | The journal of supportive oncology 20070601 |
| In vitro simulation study of individualized chemotherapy in lung cancer. | Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20070601 |
| Extensive colonic ischemia following treatment with bevacizumab, fluouracil and CPT-11 in a young patient with advanced adenocarcinoma of the rectum. | The Israel Medical Association journal : IMAJ 20070601 |
| Evaluation of adjuvant chemotherapy irinotecan + 5-fluorouracil + leucovorine in advanced colorectal cancer. | Acta chirurgica Belgica 20070601 |
| Schedule-dependent cytotoxicity of 5-fluorouracil and irinotecan in p53 mutant human colon cancer. | Journal of experimental & clinical cancer research : CR 20070601 |
| Sunitinib: a novel tyrosine kinase inhibitor. A brief review of its therapeutic potential in the treatment of renal carcinoma and gastrointestinal stromal tumors (GIST). | Therapeutics and clinical risk management 20070601 |
| A review of the role of capecitabine in the treatment of colorectal cancer. | Therapeutics and clinical risk management 20070601 |
| Cetuximab in the management of colorectal cancer. | Biologics : targets & therapy 20070601 |
| Cetuximab, a chimeric human mouse anti-epidermal growth factor receptor monoclonal antibody, in the treatment of human colorectal cancer. | Oncogene 20070528 |
| Current role of antibody therapy in patients with metastatic colorectal cancer. | Oncogene 20070528 |
| A phase II study of biweekly dose-intensified oral capecitabine plus irinotecan (bXELIRI) for patients with advanced or metastatic gastric cancer. | British journal of cancer 20070521 |
| Copper-transporting P-type ATPase, ATP7A, confers multidrug resistance and its expression is related to resistance to SN-38 in clinical colon cancer. | Cancer research 20070515 |
| A preclinical evaluation of pemetrexed and irinotecan combination as second-line chemotherapy in pancreatic cancer. | British journal of cancer 20070507 |
| First-line treatment with oxaliplatin and capecitabine in patients with advanced or metastatic oesophageal cancer: a phase II study. | British journal of cancer 20070507 |
| Antitumor activity of trastuzumab in combination with chemotherapy in human gastric cancer xenograft models. | Cancer chemotherapy and pharmacology 20070501 |
| Intensified neoadjuvant radiochemotherapy for locally advanced rectal cancer: a review. | International journal of colorectal disease 20070501 |
| Thrombotic microangiopathy and anti-VEGF agents. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501 |
| Effect of combined therapy with low-dose 5-aza-2'-deoxycytidine and irinotecan on colon cancer cell line HCT-15. | Annals of surgical oncology 20070501 |
| Efficacy of increasing the therapeutic index of irinotecan, plasma and tissue selenium concentrations is methylselenocysteine dose dependent. | Biochemical pharmacology 20070501 |
| Simultaneous determination of irinotecan (CPT-11) and SN-38 in tissue culture media and cancer cells by high performance liquid chromatography: application to cellular metabolism and accumulation studies. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501 |
| Imexon-based combination chemotherapy in A375 human melanoma and RPMI 8226 human myeloma cell lines. | Cancer chemotherapy and pharmacology 20070501 |
| A phase II study using a topoisomerase I-based approach in patients with multiply relapsed germ-cell tumours. | Annals of oncology : official journal of the European Society for Medical Oncology 20070501 |
| Phase II trial of irinotecan and cisplatin with early concurrent radiotherapy in limited-disease small-cell lung cancer. | Cancer 20070501 |
| CpG island methylation, response to combination chemotherapy, and patient survival in advanced microsatellite stable colorectal carcinoma. | Virchows Archiv : an international journal of pathology 20070501 |
| Combination of SN-38 with gefitinib or imatinib overcomes SN-38-resistant small-cell lung cancer cells. | Oncology reports 20070501 |
| Sensitivity to CPT-11 and platinum derivatives of stage III/Dukes' C colorectal cancer with occult neoplastic cells in lymph node sinuses. | Oncology reports 20070501 |
| Sensitivity to CPT-11 and platinum derivatives of stage II/Dukes' B colorectal cancer with occult neoplastic cells in lymph node sinuses. | Oncology reports 20070501 |
| Successful treatment of leptomeningeal disease in colorectal cancer with a regimen of bevacizumab, temozolomide, and irinotecan. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070501 |
| Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: the Gruppo Oncologico Nord Ovest. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070501 |
| Acute myelogenous leukemia following irinotecan-based chemotherapy for adenocarcinoma of the small intestine. | Leukemia & lymphoma 20070501 |
| [A case of ascending colon cancer with enlarged metastatic lymph nodes around superior mesenteric arterial root that responded dramatically to S-1 and CPT-11 combination chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070501 |
| [Adjuvant chemotherapy for colorectal cancer in Japan-current state and problem areas]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070501 |
| Integration of novel agents into combined-modality treatment for rectal cancer patients. | Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20070501 |
| Cellular FLICE-inhibitory protein regulates chemotherapy-induced apoptosis in breast cancer cells. | Molecular cancer therapeutics 20070501 |
| Local and distant immune-mediated control of colon cancer growth with fusogenic membrane glycoproteins in combination with viral oncolysis. | Human gene therapy 20070501 |
| 4-IBP, a sigma1 receptor agonist, decreases the migration of human cancer cells, including glioblastoma cells, in vitro and sensitizes them in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugs. | Neoplasia (New York, N.Y.) 20070501 |
| Serum total bilirubin as a predictive factor for severe neutropenia in lung cancer patients treated with cisplatin and irinotecan. | Japanese journal of clinical oncology 20070501 |
| Establishment and characterization of an IGSK-2 cell line derived from ascitic fluid of recurrent hCG and somatostatin secreted adenocarcinoma of the stomach. | Human cell 20070501 |
| Phase II trial of oxaliplatin/irinotecan/5-fluorouracil/leucovorin for metastatic colorectal cancer. | Clinical colorectal cancer 20070501 |
| Phase I study of irinotecan and gemcitabine in previously untreated patients with advanced non-small cell lung cancer. | Japanese journal of clinical oncology 20070501 |
| Vascular disrupting agents in clinical development. | British journal of cancer 20070423 |
| An individual patient data meta-analysis of adjuvant therapy with uracil-tegafur (UFT) in patients with curatively resected rectal cancer. | British journal of cancer 20070423 |
| Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by Cetuximab plus chemotherapy. | British journal of cancer 20070423 |
| Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070420 |
| Heat shock protein 27 is associated with irinotecan resistance in human colorectal cancer cells. | FEBS letters 20070417 |
| Safe liver resection following chemotherapy for colorectal metastases is a matter of timing. | British journal of cancer 20070410 |
| Oxaliplatin, 5-fluorouracil/leucovorin and epirubicin as first-line treatment in advanced gastric carcinoma: a phase II study. | British journal of cancer 20070410 |
| [Diagnosis of and therapy for pancreatic neoplasms]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20070410 |
| [Establishment of a multi drug-resistant human lung adenocarcinoma cell line and biological characteristics there of]. | Zhonghua yi xue za zhi 20070403 |
| Influence of low-energy laser in the prevention of oral mucositis in children with cancer receiving chemotherapy. | Pediatric blood & cancer 20070401 |
| Antitumor activity of HER1/EGFR tyrosine kinase inhibitor erlotinib, alone and in combination with CPT-11 (irinotecan) in human colorectal cancer xenograft models. | Cancer chemotherapy and pharmacology 20070401 |
| Clinical trial of CPT-11 and VM-26/VP-16 for patients with recurrent malignant brain tumors. | Journal of neuro-oncology 20070401 |
| Mediastinal signet-ring cell carcinoma of unknown primary: long-term survival by treatment with S-1, a novel derivative of 5-fluorouracil. | Lung cancer (Amsterdam, Netherlands) 20070401 |
| Gefitinib and irinotecan in patients with fluoropyrimidine-refractory, irinotecan-naive advanced colorectal cancer: a phase I-II study. | Annals of oncology : official journal of the European Society for Medical Oncology 20070401 |
| St. John's wort and irinotecan-induced diarrhea. | Toxicology and applied pharmacology 20070401 |
| Phase I study of carboplatin in combination with gemcitabine and irinotecan in patients with solid tumors: preliminary evidence of activity in small cell and neuroendocrine carcinomas. | Cancer 20070401 |
| Exatecan in pretreated adult patients with advanced soft tissue sarcoma: results of a phase II--study of the EORTC Soft Tissue and Bone Sarcoma Group. | European journal of cancer (Oxford, England : 1990) 20070401 |
| Circulating VEGF reduction, response and outcome in advanced colorectal cancer patients treated with cetuximab plus irinotecan. | Pharmacogenomics 20070401 |
| A randomised phase II study of irinotecan in combination with 5-FU/FA compared with irinotecan alone as second-line treatment of patients with metastatic colorectal carcinoma. | Onkologie 20070401 |
| Hypoxia-targeted over-expression of carboxylesterase as a means of increasing tumour sensitivity to irinotecan (CPT-11). | The journal of gene medicine 20070401 |
| Chemotherapy for advanced gastric cancer: across the years for a standard of care. | Expert opinion on pharmacotherapy 20070401 |
| Cetuximab plus irinotecan in refractory colorectal cancer patients. | Expert review of anticancer therapy 20070401 |
| Chemotherapy for colorectal cancer in the metastatic and adjuvant setting: past, present and future. | Expert review of anticancer therapy 20070401 |
| Molecular markers of chemotherapeutic response and toxicity in colorectal cancer. | Expert review of anticancer therapy 20070401 |
| S-phase checkpoints regulate Apo2 ligand/TRAIL and CPT-11-induced apoptosis of prostate cancer cells. | Molecular cancer therapeutics 20070401 |
| [Non-cisplatin based chemotherapy in advanced non-small cell lung cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070401 |
| [Outpatient chemotherapy for lung cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070401 |
| [A case of advanced gastric cancer with obstructive jaundice due to multiple liver metastasis successfully treated with the following combination therapy of CPT-11 and cisplatin after combination therapy of paclitaxel and TS-1]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070401 |
| [A case report of gastric small cell carcinoma with long survival time by adjuvant chemotherapy--reports of chemotherapy regimens for gastric small cell carcinoma]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070401 |
| [A case of TS-1 resistant recurrent gastric cancer with lung metastasis responding to TS-1 and irinotecan combination therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070401 |
| [Second-or third-line chemotherapy with CPT-11+TS-1 for 5 cases of metastatic and recurrent colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070401 |
| [A case of effective regimen of tegafur and uracil (UFT)/leucovorin (LV) plus irinotecan (CPT-11) for advanced rectal carcinoma with severe pelvic infiltration to be performed curative resection]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070401 |
| Adjuvant treatment of colon cancer: past, present and future. | Journal of chemotherapy (Florence, Italy) 20070401 |
| The role and limitations of 18-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) scan and computerized tomography (CT) in restaging patients with hepatic colorectal metastases following neoadjuvant chemotherapy: comparison with operative and pathological findings. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20070401 |
| Adjuvant therapy for stage II and III colorectal cancer. | Seminars in oncology 20070401 |
| Developing strategies for liver metastases from colorectal cancer. | Seminars in oncology 20070401 |
| Modified Irinotecan/5FU/Leucovorin therapy in advanced colorectal cancer and predicting therapeutic efficacy by expression of tumor-related enzymes. | Scandinavian journal of gastroenterology 20070401 |
| Velafermin improves gastrointestinal mucositis following irinotecan treatment in tumor-bearing DA rats. | Cancer biology & therapy 20070401 |
| Size matters. What can we learn from a small randomized trial? | Onkologie 20070401 |
| A case of small cell carcinoma of the kidney. | Hinyokika kiyo. Acta urologica Japonica 20070401 |
| Optimizing palliative treatment of metastatic colorectal cancer in the era of biologic therapy. | Oncology (Williston Park, N.Y.) 20070401 |
| [Preparation and characterization of 7-ethyl-10-hydroxycamptothecin-loaded hypomicron of amphiphilic block copolymer]. | Yao xue xue bao = Acta pharmaceutica Sinica 20070401 |
| Irinotecan toxicity. | Current opinion in supportive and palliative care 20070401 |
| Chemotherapy in advanced biliary tract carcinoma: a pooled analysis of clinical trials. | British journal of cancer 20070326 |
| A phase II study of capecitabine and irinotecan in combination with concurrent pelvic radiotherapy (CapIri-RT) as neoadjuvant treatment of locally advanced rectal cancer. | British journal of cancer 20070326 |
| Crystal structure of the Geobacillus stearothermophilus carboxylesterase Est55 and its activation of prodrug CPT-11. | Journal of molecular biology 20070316 |
| A simple and reproducible scoring system for EGFR in colorectal cancer: application to prognosis and prediction of response to preoperative brachytherapy. | British journal of cancer 20070312 |
| Changes in the status of p53 affect drug sensitivity to thymidylate synthase (TS) inhibitors by altering TS levels. | British journal of cancer 20070312 |
| Phase I and pharmacologic study of irinotecan and amrubicin in advanced non-small cell lung cancer. | Cancer chemotherapy and pharmacology 20070301 |
| A phase II study of weekly irinotecan as first-line therapy for patients with metastatic pancreatic cancer. | Cancer chemotherapy and pharmacology 20070301 |
| Nutrition intervention using an eicosapentaenoic acid (EPA)-containing supplement in patients with advanced colorectal cancer. Effects on nutritional and inflammatory status: a phase II trial. | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20070301 |
| FOLFIRI.3, a new regimen combining 5-fluorouracil, folinic acid and irinotecan, for advanced pancreatic cancer: results of an Association des Gastro-Enterologues Oncologues (Gastroenterologist Oncologist Association) multicenter phase II study. | Annals of oncology : official journal of the European Society for Medical Oncology 20070301 |
| Acneiform eruptions associated with epidermal growth factor receptor-targeted chemotherapy. | Journal of the American Academy of Dermatology 20070301 |
| Analysis of mammalian carboxylesterase inhibition by trifluoromethylketone-containing compounds. | Molecular pharmacology 20070301 |
| Preclinical efficacy of ST1976, a novel camptothecin analog of the 7-oxyiminomethyl series. | Biochemical pharmacology 20070301 |
| A medical health report on individuals with silent butyrylcholinesterase in the Vysya community of India. | Clinica chimica acta; international journal of clinical chemistry 20070301 |
| Coencapsulation of irinotecan and floxuridine into low cholesterol-containing liposomes that coordinate drug release in vivo. | Biochimica et biophysica acta 20070301 |
| Amrubicin, a novel 9-aminoanthracycline, enhances the antitumor activity of chemotherapeutic agents against human cancer cells in vitro and in vivo. | Cancer science 20070301 |
| Evidence of clinical activity for cetuximab combined with irinotecan in a patient with refractory anal canal squamous-cell carcinoma: report of a case. | Diseases of the colon and rectum 20070301 |
| Pooled efficacy analysis from a phase I-II study of biweekly irinotecan in combination with gemcitabine, 5-fluorouracil, leucovorin and cisplatin in patients with metastatic pancreatic cancer. | Anti-cancer drugs 20070301 |
| Combined analysis of genetic polymorphisms in thymidylate synthase, uridine diphosphate glucoronosyltransferase and X-ray cross complementing factor 1 genes as a prognostic factor in advanced colorectal cancer patients treated with 5-fluorouracil plus oxaliplatin or irinotecan. | Oncology reports 20070301 |
| Chemotherapy-associated hepatotoxicity and surgery for colorectal liver metastases. | The British journal of surgery 20070301 |
| A multicentre phase I and pharmacokinetic study of BN80915 (diflomotecan) administered daily as a 20-min intravenous infusion for 5 days every 3 weeks to patients with advanced solid tumours. | Annals of oncology : official journal of the European Society for Medical Oncology 20070301 |
| ABCG2: determining its relevance in clinical drug resistance. | Cancer metastasis reviews 20070301 |
| Gene expression signature in advanced colorectal cancer patients select drugs and response for the use of leucovorin, fluorouracil, and irinotecan. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070301 |
| Systematic review and economic evaluation of bevacizumab and cetuximab for the treatment of metastatic colorectal cancer. | Health technology assessment (Winchester, England) 20070301 |
| [Lung cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070301 |
| [Chemotherapy for elderly patients with colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070301 |
| [A retrospective study of irinotecan plus fluorouracil and l-leucovorin chemotherapy for advanced and metastatic colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070301 |
| [A recurrent ovarian cancer patient who achieved a complete response following irinotecan plus CDDP therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070301 |
| Irinotecan: a potential new chemotherapeutic agent for atypical or malignant meningiomas. | Journal of neurosurgery 20070301 |
| Incidence and management of cutaneous toxicities associated with cetuximab. | Expert opinion on drug safety 20070301 |
| Medicinal cannabis does not influence the clinical pharmacokinetics of irinotecan and docetaxel. | The oncologist 20070301 |
| Phase I study of radical thoracic radiation, weekly irinotecan, and cisplatin in locally advanced non-small cell lung carcinoma. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20070301 |
| Validation of rapid polymerase chain reaction-based detection of all length polymorphisms in the UGT 1A1 gene promoter. | Diagnostic molecular pathology : the American journal of surgical pathology, part B 20070301 |
| Panitumumab with irinotecan/leucovorin/5-fluorouracil for first-line treatment of metastatic colorectal cancer. | Clinical colorectal cancer 20070301 |
| Reversible grade 4 hyperbilirubinemia in a patient with UGT1A1 7/7 genotype treated with irinotecan and cetuximab. | Clinical colorectal cancer 20070301 |
| [Relationship between the expression of P-glycoprotein, glutathione S-transferase-pi and thymidylate synthase proteins and adenosine triphosphate tumor chemosensitivity assay in cervical cancer]. | Zhonghua fu chan ke za zhi 20070301 |
| [A randomized trial of irinotecan plus fuorouracil and leucovorin with thalidomide versus without thalidomide in the treatment for advanced colorectal cancer]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20070301 |
| Hypokalemia secondary to capecitabine: a hidden toxicity? | Therapeutics and clinical risk management 20070301 |
| First line targeted therapies in breast cancer: focus on bevacizumab. | Biologics : targets & therapy 20070301 |
| Trastuzumab in the management of early and advanced stage breast cancer. | Biologics : targets & therapy 20070301 |
| [Medical therapy of progressive colorectal cancer]. | Praxis 20070227 |
| A phase I/II study of irinotecan when added to 5-fluorouracil and leucovorin and pelvic radiation in locally advanced rectal cancer: a Colorectal Clinical Oncology Group Study. | British journal of cancer 20070226 |
| Treatment of 5-fluorouracil refractory metastatic colorectal cancer: an Australian population-based analysis. | British journal of cancer 20070226 |
| The thermodynamic dissociation constants of the anticancer drugs camptothecine, 7-ethyl-10-hydroxycamptothecine, 10-hydroxycamptothecine and 7-ethylcamptothecine by the least-squares nonlinear regression of multiwavelength spectrophotometric pH-titration data. | Analytica chimica acta 20070219 |
| Chimmitecan, a novel 9-substituted camptothecin, with improved anticancer pharmacologic profiles in vitro and in vivo. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070215 |
| Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070215 |
| Phase II trial of docetaxel, cisplatin and fluorouracil followed by carboplatin and radiotherapy in locally advanced oesophageal cancer. | British journal of cancer 20070212 |
| Uracil/ftorafur/leucovorin combined with irinotecan (TEGAFIRI) or oxaliplatin (TEGAFOX) as first-line treatment for metastatic colorectal cancer patients: results of randomised phase II study. | British journal of cancer 20070212 |
| [Standard chemotherapy for colonic neoplasms]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20070210 |
| Morphology control of polylactide microspheres enclosing irinotecan hydrochloride with polylactide based polymer surfactant for reduction of initial burst. | International journal of pharmaceutics 20070207 |
| Temozolomide and intravenous irinotecan for treatment of advanced Ewing sarcoma. | Pediatric blood & cancer 20070201 |
| Adsorption of irinotecan onto oral adsorbent AST-120 (Kremezin) for preventing delayed diarrhea. | Cancer chemotherapy and pharmacology 20070201 |
| A phase II trial of weekly fractionated irinotecan and cisplatin for advanced gastric cancer. | Cancer chemotherapy and pharmacology 20070201 |
| Irinotecan changes gene expression in the small intestine of the rat with breast cancer. | Cancer chemotherapy and pharmacology 20070201 |
| Comparison of antitumor activities in tumor xenograft treatment. | Contemporary clinical trials 20070201 |
| Cytotoxic effects of histone deacetylase inhibitor FK228 (depsipeptide, formally named FR901228) in combination with conventional anti-leukemia/lymphoma agents against human leukemia/lymphoma cell lines. | Investigational new drugs 20070201 |
| Importance of histological tumor response assessment in predicting the outcome in patients with colorectal liver metastases treated with neo-adjuvant chemotherapy followed by liver surgery. | Annals of oncology : official journal of the European Society for Medical Oncology 20070201 |
| Phase II trial of irinotecan/gemcitabine as second-line therapy for relapsed and refractory small-cell lung cancer: Cancer and Leukemia Group B Study 39902. | Annals of oncology : official journal of the European Society for Medical Oncology 20070201 |
| Phase II trial of capecitabine and oxaliplatin (CAPOX) plus cetuximab in patients with metastatic colorectal cancer who progressed after oxaliplatin-based chemotherapy. | Annals of oncology : official journal of the European Society for Medical Oncology 20070201 |
| Randomized phase III study of cisplatin plus irinotecan versus carboplatin plus paclitaxel, cisplatin plus gemcitabine, and cisplatin plus vinorelbine for advanced non-small-cell lung cancer: Four-Arm Cooperative Study in Japan. | Annals of oncology : official journal of the European Society for Medical Oncology 20070201 |
| Effects of green tea compounds on irinotecan metabolism. | Drug metabolism and disposition: the biological fate of chemicals 20070201 |
| Role of p53 in irinotecan-induced intestinal cell death and mucosal damage. | Anti-cancer drugs 20070201 |
| Cetuximab in the treatment of metastatic colorectal cancer. | Expert opinion on biological therapy 20070201 |
| Data acquisition for the histoculture drug response assay in lung cancer. | The Journal of thoracic and cardiovascular surgery 20070201 |
| Phase II trial of irinotecan in children with relapsed or refractory rhabdomyosarcoma: a joint study of the French Society of Pediatric Oncology and the United Kingdom Children's Cancer Study Group. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070201 |
| Two consecutive phase II window trials of irinotecan alone or in combination with vincristine for the treatment of metastatic rhabdomyosarcoma: the Children's Oncology Group. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070201 |
| [Basic strategies on first- and second-line chemotherapy for advanced gastric cancers]. | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20070201 |
| [Up to date chemotherapy for colon cancer]. | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20070201 |
| [Clinical development of chemotherapy for advanced gastric cancer]. | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20070201 |
| Celecoxib and mucosal protection: translation from an animal model to a phase I clinical trial of celecoxib, irinotecan, and 5-fluorouracil. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070201 |
| Celecoxib prevents neuroblastoma tumor development and potentiates the effect of chemotherapeutic drugs in vitro and in vivo. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070201 |
| New, expanded, and modified use of approved antineoplastic agents in ovarian cancer. | The oncologist 20070201 |
| Circadian rhythms in the CNS and peripheral clock disorders: chronopharmacological findings on antitumor drugs. | Journal of pharmacological sciences 20070201 |
| [Feasibility of modified FOLFIRI regimen for patients with refractory advanced or recurrent colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070201 |
| Effective combination chemotherapy of carboplatin and paclitaxel in the treatment of a recurrent small-cell lung cancer patient. | Gan to kagaku ryoho. Cancer & chemotherapy 20070201 |
| A mechanistic study on altered pharmacokinetics of irinotecan by St. John's wort. | Current drug metabolism 20070201 |
| [Small cell carcinoma of the urinary bladder treated with neo-adjuvant cp chemotherapy (CPT-11 and CDDP): a case report]. | Hinyokika kiyo. Acta urologica Japonica 20070201 |
| Amrubicin for the treatment of small cell lung cancer: does effectiveness cross the Pacific? | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20070201 |
| Prevention and management of chemotherapy-induced diarrhea in patients with colorectal cancer: a consensus statement by the Canadian Working Group on Chemotherapy-Induced Diarrhea. | Current oncology (Toronto, Ont.) 20070201 |
| [Pre-operative chemotherapy for patients with hepatic metastases from colorectal cancer]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20070201 |
| Immunostaining of thymidylate synthase and p53 for predicting chemoresistance to S-1/cisplatin in gastric cancer. | British journal of cancer 20070129 |
| DCE-MRI biomarkers in the clinical evaluation of antiangiogenic and vascular disrupting agents. | British journal of cancer 20070129 |
| Cost-effectiveness analysis of cetuximab/irinotecan vs active/best supportive care for the treatment of metastatic colorectal cancer patients who have failed previous chemotherapy treatment. | British journal of cancer 20070129 |
| Mechanism of trifluorothymidine potentiation of oxaliplatin-induced cytotoxicity to colorectal cancer cells. | British journal of cancer 20070129 |
| Schedule-dependent activity of 5-fluorouracil and irinotecan combination in the treatment of human colorectal cancer: in vitro evidence and a phase I dose-escalating clinical trial. | British journal of cancer 20070115 |
| Concurrent irinotecan, oxaliplatin and UFT in first-line treatment of metastatic colorectal cancer: a phase I study. | British journal of cancer 20070115 |
| A phase I and pharmacokinetic study of pemetrexed plus irinotecan in patients with advanced solid malignancies. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070115 |
| CHIR-124, a novel potent inhibitor of Chk1, potentiates the cytotoxicity of topoisomerase I poisons in vitro and in vivo. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070115 |
| A phase I-II study of bi-weekly gemcitabine and irinotecan as second-line chemotherapy in non-small cell lung cancer after prior taxane + platinum-based regimens. | Cancer chemotherapy and pharmacology 20070101 |
| Thalidomide and celecoxib as potential modulators of irinotecan's activity in cancer patients. | Cancer chemotherapy and pharmacology 20070101 |
| Phase II trial of irinotecan plus oxaliplatin and 5-fluorouracil/leucovorin in patients with untreated metastatic gastric adenocarcinoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20070101 |
| The contribution of intestinal UDP-glucuronosyltransferases in modulating 7-ethyl-10-hydroxy-camptothecin (SN-38)-induced gastrointestinal toxicity in rats. | The Journal of pharmacology and experimental therapeutics 20070101 |
| Irinotecan drug eluting beads for use in chemoembolization: in vitro and in vivo evaluation of drug release properties. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070101 |
| Irinotecan-induced cytotoxicity to colon cancer cells in vitro is stimulated by pre-incubation with trifluorothymidine. | European journal of cancer (Oxford, England : 1990) 20070101 |
| Phase II study of the irinotecan (CPT-11), mitoxantrone and dexamethasone regimen in elderly patients with relapsed or refractory peripheral T-cell lymphoma. | Cancer science 20070101 |
| Chemotherapy for colorectal cancer prior to liver resection for colorectal cancer hepatic metastases does not adversely affect peri-operative outcomes. | Journal of surgical oncology 20070101 |
| Results from an in vitro and a clinical/pharmacological phase I study with the combination irinotecan and sorafenib. | European journal of cancer (Oxford, England : 1990) 20070101 |
| Successful treatment of childhood intramedullary spinal cord astrocytomas with irinotecan and cisplatin. | Neuro-oncology 20070101 |
| Efficacy and safety of first- or second-line irinotecan, cisplatin, and mitomycin in mesothelioma. | Cancer 20070101 |
| [Colorectal liver metastases. Neoadjuvant chemotherapy: aspects of medical and surgical oncology]. | Der Internist 20070101 |
| Irinotecan-induced diarrhea: functional significance of the polymorphic ABCC2 transporter protein. | Clinical pharmacology and therapeutics 20070101 |
| The role of SN-38 exposure, UGT1A1*28 polymorphism, and baseline bilirubin level in predicting severe irinotecan toxicity. | Journal of clinical pharmacology 20070101 |
| Chemotherapy-induced diarrhea is associated with changes in the luminal environment in the DA rat. | Experimental biology and medicine (Maywood, N.J.) 20070101 |
| Tumor-targeted enzyme/prodrug therapy mediates long-term disease-free survival of mice bearing disseminated neuroblastoma. | Cancer research 20070101 |
| [Chemotherapy in advanced gastric cancer--to ensure timely and appropriate switch to subsequent treatment options]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070101 |
| [Superficial small cell carcinoma of esophagus treated by endoscopic mucosal resection combined with chemoradiotherapy--a case report]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070101 |
| [A case of stage IV gastric cancer treated sequentially for over two years by TS-1, paclitaxel, and CPT-11]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070101 |
| [Successful CPT-11 treatment in a patient with pancreatic cancer associated with multiple liver metastases and chronic renal failure]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070101 |
| [A case of recurrent colon cancer with urinary bladder, para-aortic lymph nodes, and spleen metastases successfully treated with CPT-11]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070101 |
| [CR of rectal cancer and synchronous liver and lung metastases obtained with TS-1 plus CPT-11 combination therapy--case report]. | Gan to kagaku ryoho. Cancer & chemotherapy 20070101 |
| Anti-tumor effect of bisphosphonate (YM529) on non-small cell lung cancer cell lines. | BMC cancer 20070101 |
| High mobility group A2 is a target for miRNA-98 in head and neck squamous cell carcinoma. | Molecular cancer 20070101 |
| Human carboxylesterase 1A2 expressed from carboxylesterase 1A1 and 1A2 genes is a potent predictor of CPT-11 cytotoxicity in vitro. | Pharmacogenetics and genomics 20070101 |
| Individualized drug therapy. | Current opinion in drug discovery & development 20070101 |
| Colorectal cancer. | Mayo Clinic proceedings 20070101 |
| Genetic diagnosis for chemosensitivity with drug-resistance genes in epithelial ovarian cancer. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20070101 |
| Phase II study of irinotecan plus doxorubicin for early recurrent or platinum-refractory ovarian cancer: interim analysis. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20070101 |
| Systemic anticancer therapy in gynecological cancer patients with renal dysfunction. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20070101 |
| Severe diarrhea in patients with advanced-stage colorectal cancer receiving FOLFOX or FOLFIRI chemotherapy: the development of a risk prediction tool. | Clinical colorectal cancer 20070101 |
| Low-dose chemotherapy with leucovorin plus 5-fluorouracil for colorectal cancer can maintain host immunity. | Anticancer research 20070101 |
| Three-dimensional cellular spheroid formation provides human prostate tumor cells with tissue-like features. | Anticancer research 20070101 |
| Retrospective evaluation of sequential outpatient chemotherapy for advanced gastric cancer. | Chemotherapy 20070101 |
| Safety and efficacy of Y-90 microsphere treatment in patients with primary and metastatic liver cancer: the tumor selectivity of the treatment as a function of tumor to liver flow ratio. | Journal of translational medicine 20070101 |
| Clinical benefit of readministration of gefitinib for initial gefitinib-responders with non-small cell lung cancer. | BMC cancer 20070101 |
| Irinotecan plus weekly 5-fluorouracil and leucovorin as salvage treatment for patients with metastatic colorectal cancer: a phase II trial. | Digestive diseases (Basel, Switzerland) 20070101 |
| Impact of pharmacogenomics on clinical practice in oncology. | Molecular diagnosis & therapy 20070101 |
| Contribution of oncoproteomics to cancer biomarker discovery. | Molecular cancer 20070101 |
| [A prevalent genetic variety of UDP-glycuronosyl transferase predicts high risk of irinotecan toxicity]. | Medicina 20070101 |
| Triple combination chemotherapy with cisplatin, docetaxel, and irinotecan for advanced non-small cell lung cancer: a phase I/II trial. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20070101 |
| Current medical treatment of pancreatic neuroendocrine tumors. | Hepato-gastroenterology 20070101 |
| Genetic tests for predicting the toxicity and efficacy of anticancer chemotherapy. | Neoplasma 20070101 |
| Interventionally implanted port catheter systems for hepatic arterial infusion of chemotherapy in patients with colorectal liver metastases: a Phase II-study and historical comparison with the surgical approach. | BMC cancer 20070101 |
| The camptothecin derivative CPT-11 inhibits angiogenesis in a dual-color imageable orthotopic metastatic nude mouse model of human colon cancer. | Anticancer research 20070101 |
| CPT-11 (SN-38) chemotherapy may be selectively applicable to biliary tract cancer with low hMLH1 expression. | Anticancer research 20070101 |
| Multicenter phase II study of irinotecan plus bolus fluorouracil/l-leucovorin for metastasic colorectal cancer. | Anticancer research 20070101 |
| Primary rectal carcinoma in patients with stage IV resectable disease at diagnosis. | Anticancer research 20070101 |
| Adaptive evolution of multiple-variable exons and structural diversity of drug-metabolizing enzymes. | BMC evolutionary biology 20070101 |
| Panitumumab in metastatic colorectal cancer. | Clinical advances in hematology & oncology : H&O 20070101 |
| Sequential administration of 5-fluorouracil (5FU)/leucovorin (LV) followed by irinotecan (CPT-11) at relapse versus CPT-11 followed by 5-FU/LV in advanced colorectal carcinoma. A phase III randomized study. | Chemotherapy 20070101 |
| Meta analysis of advanced cancer survival data using lognormal parametric fitting: a statistical method to identify effective treatment protocols. | Current pharmaceutical design 20070101 |
| Adjuvant treatment of colorectal cancer. | CA: a cancer journal for clinicians 20070101 |
| Development and clinical indications of cetuximab. | The International journal of biological markers 20070101 |
| Cetuximab in colon cancer. | The International journal of biological markers 20070101 |
| The future of anti-EGFR therapy. | The International journal of biological markers 20070101 |
| A Phase I dose-finding study using an innovative sequential biweekly schedule of irinotecan followed 24 hours later by capecitabine. | Cancer investigation 20070101 |
| Front-line bevacizumab in combination with oxaliplatin, leucovorin and 5-fluorouracil (FOLFOX) in patients with metastatic colorectal cancer: a multicenter phase II study. | BMC cancer 20070101 |
| Feasible combination chemotherapy with nedaplatin and irinotecan for patients with non-small cell lung cancer and multiple high-risk factors. | Journal of experimental therapeutics & oncology 20070101 |
| Cetuximab and irinotecan as third line therapy in patients with advanced colorectal cancer after failure of irinotecan, oxaliplatin and 5-fluorouracil. | Acta oncologica (Stockholm, Sweden) 20070101 |
| Analysis of risk factors for severe adverse effects of oral 5-fluorouracil S-1 in patients with advanced gastric cancer. | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20070101 |
| A patient with 43 synchronous early gastric carcinomas with a Krukenberg tumor and pericardial metastasis. | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20070101 |
| [Irinotecan and liver dysfunctions]. | Therapie 20070101 |
| Impact of phase II trials with progression-free survival as end-points on survival-based phase III studies in patients with anaplastic gliomas. | BMC cancer 20070101 |
| Pilot study of simplified low-dose S-1 plus CPT-11 as first-line chemotherapy for patients with advanced colorectal cancer. | Anticancer research 20070101 |
| Dose escalating clinical study of high dose infusional 5-fluorouracil and leukovorin (AIO regimen) plus alternate weekly administration of oxaliplatin and irinotecan in patients with advanced tumors of the gastrointestinal tract. | Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20070101 |
| Prediction of efficacy and side effects of chemotherapy in colorectal cancer. | Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20070101 |
| Cetuximab: appraisal of a novel drug against colorectal cancer. | Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20070101 |
| Cost considerations in the treatment of colorectal cancer. | PharmacoEconomics 20070101 |
| Esophageal cancer: adjuvant therapy. | Cancer journal (Sudbury, Mass.) 20070101 |
| Adjuvant therapy of colon cancer: current status and future directions. | Cancer journal (Sudbury, Mass.) 20070101 |
| HIPEC with oxaliplatin in the treatment of peritoneal carcinomatosis of colorectal origin. | Cancer treatment and research 20070101 |
| Systemic chemotherapy in patients with peritoneal carcinomatosis from colorectal cancer. | Cancer treatment and research 20070101 |
| Successful paclitaxel-based chemotherapy for an alpha-fetoprotein-producing gastric cancer patient with multiple liver metastases. | World journal of surgical oncology 20070101 |
| Shiga toxin-mediated retrograde delivery of a topoisomerase I inhibitor prodrug. | Angewandte Chemie (International ed. in English) 20070101 |
| A pilot phase II study of chemotherapy with oxaliplatin, folinic acid, 5-fluorouracil and irinotecan in metastatic gastric cancer. | Tumori 20070101 |
| Significance of thymidine phosphorylase in metronomic chemotherapy using CPT-11 and doxifluridine for advanced colorectal carcinoma. | Anticancer research 20070101 |
| Phase I/II study of irinotecan and UFT for advanced or metastatic colorectal cancer. | Anticancer research 20070101 |
| Complete remission of ovarian small cell carcinoma treated with irinotecan and cisplatin: a case report. | Anticancer research 20070101 |
| Palliative chemotherapy for recurrent and metastatic esophageal cancer. | Anticancer research 20070101 |
| Neoadjuvant chemotherapy with irinotecan and mitomycin-C for locally advanced squamous cell carcinoma of the uterine cervix. | Anticancer research 20070101 |
| A phase II trial of weekly irinotecan in cisplatin-refractory esophageal cancer. | Anticancer research 20070101 |
| Expression of a molecular marker panel as a prognostic tool in gastric cancer patients treated postoperatively with docetaxel and irinotecan. A study of the Hellenic Cooperative Oncology Group. | Anticancer research 20070101 |
| Second-line chemotherapy of platinum compound plus CPT-11 following ADOC chemotherapy in advanced thymic carcinoma: analysis of seven cases. | Anticancer research 20070101 |
| Irinotecan and S-1 neoadjuvant chemoradiation therapy in patients with advanced rectal cancer. | Hepato-gastroenterology 20070101 |
| Establishment of a single-dose irinotecan model of gastrointestinal mucositis. | Chemotherapy 20070101 |
| Evaluation of HI-6 oxime: potential use in protection of human acetylcholinesterase inhibited by antineoplastic drug irinotecan and its cyto/genotoxicity in vitro. | Acta biochimica Polonica 20070101 |
| Mismatch repair status is a predictive factor of tumour response to 5-fluorouracil and irinotecan chemotherapy in patients with advanced colorectal cancer. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20070101 |
| Metastatic colorectal cancer: current systemic treatment options. | Drugs 20070101 |
| Phase II trial of weekly docetaxel/irinotecan combination in advanced pancreatic cancer. | Cancer journal (Sudbury, Mass.) 20070101 |
| A general review of the role of irinotecan (CPT11) in the treatment of gastric cancer. | Medical oncology (Northwood, London, England) 20070101 |
| Clinical trial update: implications and management of residual disease after neoadjuvant therapy for breast cancer. | Breast cancer research : BCR 20070101 |
| Increased preclinical efficacy of irinotecan and floxuridine coencapsulated inside liposomes is associated with tumor delivery of synergistic drug ratios. | Oncology research 20070101 |
| Secondary treatment and predictive factors for second-line chemotherapy after first-line oxaliplatin-based therapy in metastatic colorectal cancer. | Acta oncologica (Stockholm, Sweden) 20070101 |
| An update on treatment advances for the first-line therapy of metastatic colorectal cancer. | Cancer journal (Sudbury, Mass.) 20070101 |
| Modern management of small-cell lung cancer. | Drugs 20070101 |
| Complications after oesophagectomy with possible contribution of neoadjuvant therapy including an EGFR-antibody to a fatal outcome. | World journal of surgical oncology 20070101 |
| Responses of cancer cells with wild-type or tyrosine kinase domain-mutated epidermal growth factor receptor (EGFR) to EGFR-targeted therapy are linked to downregulation of hypoxia-inducible factor-1alpha. | Molecular cancer 20070101 |
| Safety and cost-effectiveness of single dose dispensing of bevacizumab for various retinal pathologies in developing countries. | Indian journal of ophthalmology 20070101 |
| Pharmacodynamic study of the Saltz regimen for metastatic colorectal cancer in a hemodialyzed patient. | Chemotherapy 20070101 |
| Impact of imatinib on the pharmacokinetics and in vivo efficacy of etoposide and/or ifosfamide. | BMC pharmacology 20070101 |
| [Angiogenesis targeting in gastro-intestinal cancers]. | Bulletin du cancer 20070101 |
| [Predictive factors of response to targeted therapies: the example of colorectal cancer]. | Bulletin du cancer 20070101 |
| A novel camptothecin analog with enhanced antitumor activity. | Anticancer research 20070101 |
| Clinical trials update: endocrine and biological therapy combinations in the treatment of breast cancer. | Breast cancer research : BCR 20070101 |
| Phase II clinical trial for prevention of delayed diarrhea with cholestyramine/levofloxacin in the second-line treatment with irinotecan biweekly in patients with metastatic colorectal carcinoma. | Oncology 20070101 |
| Phase I study of S-1 combined with irinotecan (CPT-11) in patients with advanced colorectal cancer. | Oncology 20070101 |
| Cetuximab: a review of its use in squamous cell carcinoma of the head and neck and metastatic colorectal cancer. | Drugs 20070101 |
| Immunohistochemical identification of primary peritoneal serous cystadenocarcinoma mimicking advanced colorectal carcinoma: a case report. | Journal of medical case reports 20070101 |
| Computational analysis of biological functions and pathways collectively targeted by co-expressed microRNAs in cancer. | BMC bioinformatics 20070101 |
| Irinotecan hydrochloride (CPT-11) and cisplatin as first-line chemotherapy after initial surgery for ovarian clear cell adenocarcinoma. | International surgery 20070101 |
| Optimal management strategies for rhabdomyosarcoma in children. | Paediatric drugs 20070101 |
| The multidisciplinary management of gastrointestinal cancer. Multimodal treatment of gastric cancer. | Best practice & research. Clinical gastroenterology 20070101 |
| The multidisciplinary management of gastrointestinal cancer. The integration of cytotoxics and biologicals in the treatment of metastatic colorectal cancer. | Best practice & research. Clinical gastroenterology 20070101 |
| Nitrosylcobalamin potentiates the anti-neoplastic effects of chemotherapeutic agents via suppression of survival signaling. | PloS one 20070101 |
| Biological characterization of two xenografts derived from human CUPs (carcinomas of unknown primary). | BMC cancer 20070101 |
| Spontaneous immune responses against glioma-associated antigens in a long term survivor with malignant glioma. | Journal of translational medicine 20070101 |
| Acneiform eruption induced by cetuximab. | Acta dermatovenerologica Croatica : ADC 20070101 |
| The fungus Ustilago maydis and humans share disease-related proteins that are not found in Saccharomyces cerevisiae. | BMC genomics 20070101 |
| Phase I dose escalation study of vinorelbine and topotecan combination chemotherapy in patients with recurrent lung cancer. | BMC cancer 20070101 |
| [Updated strategies in Small Cell Lung Cancer post ASCO 2007]. | Wiener medizinische Wochenschrift (1946) 20070101 |
| Irinotecan plus gemcitabine and 5-fluorouracil in advanced pancreatic cancer: a phase II study. | Oncology 20070101 |
| Intraarterial hepatic chemoembolization of liver metastases from colorectal cancer adopting irinotecan-eluting beads: results of a phase II clinical study. | In vivo (Athens, Greece) 20070101 |
| Long-term survivors after chemotherapy in advanced non-small cell lung cancer. | Anticancer research 20070101 |
| Antiangiogenic therapy in malignant glioma: promise and challenge. | Current pharmaceutical design 20070101 |
| Defective differentiation of myeloid and plasmacytoid dendritic cells in advanced cancer patients is not normalized by tyrosine kinase inhibition of the vascular endothelial growth factor receptor. | Clinical & developmental immunology 20070101 |
| A randomized phase II trial of pemetrexed plus irinotecan (ALIRI) versus leucovorin-modulated 5-FU plus irinotecan (FOLFIRI) in first-line treatment of locally advanced or metastatic colorectal cancer. | Oncology 20070101 |
| Phase II study of a combination of irinotecan and S-1 in patients with advanced gastric cancer (OGSG0002). | Oncology 20070101 |
| Phase II study of a 3-week schedule of irinotecan combined with cisplatin in previously untreated extensive-stage small-cell lung cancer. | Oncology 20070101 |
| [The choice of treatment in advanced gastric cancer]. | Tumori 20070101 |
| Cost-effectiveness of cetuximab in combination with irinotecan compared with current care in metastatic colorectal cancer after failure on irinotecan--a Belgian analysis. | Acta clinica Belgica 20070101 |
| [Combination chemotherapy with newly-developed cytostatics for disseminated small cell lung cancer]. | Voprosy onkologii 20070101 |
| Assessment of baseline clinical predictive factors of response to cetuximab-irinotecan in patients with irinotecan-refractory metastatic colorectal cancer. | Oncology 20070101 |
| XELOX followed by XELIRI or the reverse sequence in advanced colorectal cancer. | Oncology 20070101 |
| Thymidylate synthase gene expression in primary tumors predicts activity of s-1-based chemotherapy for advanced gastric cancer. | Gastrointestinal cancer research : GCR 20070101 |
| Chemotherapy for advanced gastric cancer: review of global and Japanese status. | Gastrointestinal cancer research : GCR 20070101 |
| Current status of adjuvant therapy for colon cancer. | Gastrointestinal cancer research : GCR 20070101 |
| Preoperative chemoradiotherapy in the management of localized rectal cancer: the new standard. | Gastrointestinal cancer research : GCR 20070101 |
| Second-line therapy for advanced colorectal cancer. | Gastrointestinal cancer research : GCR 20070101 |
| Predictive and prognostic markers in colorectal cancer. | Gastrointestinal cancer research : GCR 20070101 |
| Recent Developments in Cytotoxic Therapy for Advanced Gastric or Gastroesophageal Carcinoma: The Phase III Trials. | Gastrointestinal cancer research : GCR 20070101 |
| ABCB1, SLCO1B1 and UGT1A1 gene polymorphisms are associated with toxicity in metastatic colorectal cancer patients treated with first-line irinotecan. | Drug metabolism letters 20070101 |
| Antiangiogenic agents in first-line and second-line therapy for advanced colorectal cancer. | Gastrointestinal cancer research : GCR 20070101 |
| Discussion on the use of taxanes for treatment of breast cancers in BRCA1 mutations carriers. | Hereditary cancer in clinical practice 20070101 |
| Panitumumab: the evidence of its therapeutic potential in metastatic colorectal cancer care. | Core evidence 20070101 |
| Aprepitant: the evidence for its place in the prevention of chemotherapy-induced nausea and vomiting. | Core evidence 20070101 |
| Bevacizumab: the evidence for its clinical potential in the treatment of nonsmall cell lung cancer. | Core evidence 20070101 |
| FOLFIRI Is Tolerable after Subtotal Colectomy - A Patient with Familial Adenomatous Polyposis Who Developed Advanced Rectal Cancer. | Case reports in gastroenterology 20070101 |
| Resection of colorectal liver metastases following neoadjuvant chemotherapy. | Ecancermedicalscience 20070101 |
| A phase II trial of S-1 monotherapy in metastatic colorectal cancer after failure of irinotecan- and oxaliplatin-containing regimens. | British journal of cancer 20061218 |
| Three-week schedule of irinotecan plus cisplatin in patients with previously untreated extensive-stage small-cell lung cancer. | British journal of cancer 20061218 |
| Phase I/II study of S-1 combined with paclitaxel in patients with unresectable and/or recurrent advanced gastric cancer. | British journal of cancer 20061218 |
| Molecular determination of epidermal growth factor receptor in normal and neoplastic colorectal mucosa. | British journal of cancer 20061204 |
| Chemotherapy with bevacizumab, irinotecan, 5-fluorouracil and leucovorin (IFL) associated with a large, embolizing thrombus in the thoracic aorta. | Annals of oncology : official journal of the European Society for Medical Oncology 20061201 |
| Intestinal tract injury by drugs: Importance of metabolite delivery by yellow bile road. | Pharmacology & therapeutics 20061201 |
| A Phase 2 trial of the liposomal DACH platinum L-NDDP in patients with therapy-refractory advanced colorectal cancer. | Cancer chemotherapy and pharmacology 20061201 |
| Phase I trial of cetuximab in combination with capecitabine, weekly irinotecan, and radiotherapy as neoadjuvant therapy for rectal cancer. | International journal of radiation oncology, biology, physics 20061201 |
| Phase II study of carboplatin, irinotecan, and thalidomide combination in patients with extensive stage small-cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20061201 |
| A phase II trial of fractionated irinotecan plus carboplatin for previously untreated extensive-disease small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20061201 |
| Transition metal-mediated liposomal encapsulation of irinotecan (CPT-11) stabilizes the drug in the therapeutically active lactone conformation. | Pharmaceutical research 20061201 |
| A Phase I study of bortezomib plus irinotecan in patients with advanced solid tumors. | Cancer 20061201 |
| Adjuvant chemotherapy with irinotecan hydrochloride and cisplatin for clear cell carcinoma of the ovary. | Oncology reports 20061201 |
| Adding pharmacogenetics information to drug labels: lessons learned. | Pharmacogenetics and genomics 20061201 |
| Efficacy of oncolytic herpesvirus NV1020 can be enhanced by combination with chemotherapeutics in colon carcinoma cells. | Human gene therapy 20061201 |
| Consistent liver metastases in a rat model by portal injection of microencapsulated cancer cells. | Cancer research 20061201 |
| Targeting the expression of platelet-derived growth factor receptor by reactive stroma inhibits growth and metastasis of human colon carcinoma. | The American journal of pathology 20061201 |
| [Thymic basaloid carcinoma]. | Kyobu geka. The Japanese journal of thoracic surgery 20061201 |
| [Routine chemotherapeutic drug treatment effectiveness predictive molecules and chemotherapeutic drug selection]. | Ai zheng = Aizheng = Chinese journal of cancer 20061201 |
| Planned treatment interruptions and chemotherapy-free intervals in the treatment of metastatic colorectal cancer: time to start stopping? | Seminars in oncology 20061201 |
| Is there a third-line therapy for metastatic colorectal cancer? | Seminars in oncology 20061201 |
| Should preoperative or postoperative therapy be administered in the management of rectal cancer? | Seminars in oncology 20061201 |
| Pharmacogenetics of irinotecan: clinical perspectives on the utility of genotyping. | Pharmacogenomics 20061201 |
| [Combination chemotherapy with hepatic arterial infusion of 5-fluorouracil (5-FU) and systemic irinotecan (CPT-11) in patients with unresectable liver metastases from colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20061201 |
| [A recurrent endocrine cell cancer of the stomach showing almost complete remission after chemotherapy for 1 year]. | Gan to kagaku ryoho. Cancer & chemotherapy 20061201 |
| Gefitinib in combination with 5-fluorouracil (5-FU)/folinic acid and irinotecan in patients with 5-FU/oxaliplatin- refractory colorectal cancer: a phase I/II study of the Arbeitsgemeinschaft für Internistische Onkologie (AIO). | Onkologie 20061201 |
| Schedule-dependent cytotoxicity of 5-fluorouracil and irinotecan in a colon cancer cell line. | Journal of gastroenterology 20061201 |
| Treatment of metastatic colorectal cancer: from cytotoxic agents to molecular agents and multitargeted strategies. | Oncology (Williston Park, N.Y.) 20061201 |
| [Outpatient chemotherapy in gynecologic oncology]. | Gan to kagaku ryoho. Cancer & chemotherapy 20061201 |
| Ranibizumab in neovascular age-related macular degeneration. | Clinical interventions in aging 20061201 |
| Evaluation of irinotecan drug-eluting beads: a new drug-device combination product for the chemoembolization of hepatic metastases. | Journal of controlled release : official journal of the Controlled Release Society 20061128 |
| A bacterial protein enhances the release and efficacy of liposomal cancer drugs. | Science (New York, N.Y.) 20061124 |
| Gemcitabine and carboplatin in carcinoma of unknown primary site: a phase 2 Adelaide Cancer Trials and Education Collaborative study. | British journal of cancer 20061120 |
| Multicenter phase II study of irinotecan, cisplatin, and bevacizumab in patients with metastatic gastric or gastroesophageal junction adenocarcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061120 |
| Phase II study of etoposide and cisplatin with concurrent twice-daily thoracic radiotherapy followed by irinotecan and cisplatin in patients with limited-disease small-cell lung cancer: West Japan Thoracic Oncology Group 9902. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061120 |
| Irinotecan plus temozolomide for relapsed or refractory neuroblastoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061120 |
| [Long-term beneficial effects of cetuximab in a woman with metastasised rectal carcinoma without expression of the epidermal growth factor receptor]. | Nederlands tijdschrift voor geneeskunde 20061118 |
| Molecular determinants of irinotecan efficacy. | International journal of cancer 20061115 |
| Pharmacogenetics and irinotecan therapy. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20061115 |
| Searching for the Holy Grail of oncology. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20061115 |
| Biological properties of IDN5174, a new synthetic camptothecin with the open lactone ring. | Cancer research 20061115 |
| Fractionated administration of irinotecan and cisplatin in Japanese patients with extensive-stage-disease small-cell lung cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061110 |
| Cost-effectiveness of oxaliplatin and capecitabine in the adjuvant treatment of stage III colon cancer. | British journal of cancer 20061106 |
| Vinflunine: a new active drug for second-line treatment of advanced breast cancer. Results of a phase II and pharmacokinetic study in patients progressing after first-line anthracycline/taxane-based chemotherapy. | British journal of cancer 20061106 |
| BCRP/ABCG2 levels account for the resistance to topoisomerase I inhibitors and reversal effects by gefitinib in non-small cell lung cancer. | Cancer chemotherapy and pharmacology 20061101 |
| Irinotecan in combination with thalidomide in patients with advanced solid tumors: a clinical study with pharmacodynamic and pharmacokinetic evaluation. | Cancer chemotherapy and pharmacology 20061101 |
| Correlation between tumor response to first-line chemotherapy and prognosis in advanced gastric cancer patients. | Annals of oncology : official journal of the European Society for Medical Oncology 20061101 |
| The prognostic significance of pretreatment plasma levels of insulin-like growth factor (IGF)-1, IGF-2, and IGF binding protein-3 in patients with advanced non-small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20061101 |
| Aberrant promoter methylation of the ABCG2 gene in renal carcinoma. | Molecular and cellular biology 20061101 |
| Irinotecan in the treatment of colorectal cancer. | Cancer treatment reviews 20061101 |
| Transcriptional activation of the carboxylesterase 2 gene by the p53 pathway. | Cancer biology & therapy 20061101 |
| Pharmacogenetic impact of polymorphisms in the coding region of the UGT1A1 gene on SN-38 glucuronidation in Japanese patients with cancer. | Cancer science 20061101 |
| Real-time imaging and quantification of brain delivery of liposomes. | Pharmaceutical research 20061101 |
| Irinotecan cytotoxicity does not necessarily depend on the UGT1A1 polymorphism but on fluoropyrimidine: a molecular case report. | Oncology reports 20061101 |
| [A case of long-term survival of 3-years 4 months after combination chemotherapy of MTX, 5-FU and low-dose CDDP (MFP) for type 4 gastric cancer with pleuritis, peritoneal dissemination and Krukenberg tumor]. | Gan to kagaku ryoho. Cancer & chemotherapy 20061101 |
| [A case of advanced rectal carcinoma with multiple lung metastases responding to irinotecan combined with 5-fluorouracil and l-leucovorin (IFL) as neoadjuvant chemotherapy (NAC)]. | Gan to kagaku ryoho. Cancer & chemotherapy 20061101 |
| [What happened during these 12 years since CPT-11 was launched in Japan ?]. | Gan to kagaku ryoho. Cancer & chemotherapy 20061101 |
| [Place of neoadjuvant treatments in oesophageal cancers care]. | Bulletin du cancer 20061101 |
| Pharmacogenetic approach for cancer treatment-tailored medicine in practice. | Annals of the New York Academy of Sciences 20061101 |
| 5-fluorouracil and mitomycin-C: effective, low-cost chemotherapy for colorectal cancer. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20061101 |
| [Evaluation of bronchial arterial infusion (BAI) for lung cancer with brain metastasis]. | Gan to kagaku ryoho. Cancer & chemotherapy 20061101 |
| [A case report of small cell carcinoma of the esophagus successfully treated by irinotecan and cisplatin]. | Gan to kagaku ryoho. Cancer & chemotherapy 20061101 |
| A case report--The marked response to gemcitabine combined with irinotecan and low-dose cisplatin chemotherapy for advanced gastric cancer with multiple liver metastases. | Gan to kagaku ryoho. Cancer & chemotherapy 20061101 |
| [A case of successfully treated unresectable multiple liver metastases from colon cancer by hepatic arterial infusion chemotherapy and systemic chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20061101 |
| [A treatment for pulmonary metastases from colorectal cancer by pre-operative CPT-11/5'-DFUR combination therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20061101 |
| Establishment and characterization of a cell line derived from a human serous surface papillary carcinoma of the ovary. | Human cell 20061101 |
| [Small cell lung cancer (CPC). Second line treatment]. | Revue des maladies respiratoires 20061101 |
| A phase II study of irinotecan and carboplatin in advanced non-small cell lung cancer with pharmacogenomic analysis: final report. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20061101 |
| Phase II study of protracted irinotecan infusion and a low-dose cisplatin for metastatic gastric cancer. | World journal of gastroenterology 20061028 |
| TIMP-1 gene deficiency increases tumour cell sensitivity to chemotherapy-induced apoptosis. | British journal of cancer 20061023 |
| Randomized phase II trial of docetaxel/irinotecan and gemcitabine/irinotecan with or without celecoxib in the second-line treatment of non-small-cell lung cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061020 |
| Multicenter phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidines. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061020 |
| Irinotecan plus cisplatin compared with etoposide plus cisplatin for small cell lung cancer: a randomized clinical trial. | Zhongguo fei ai za zhi = Chinese journal of lung cancer 20061020 |
| St. John's wort attenuates irinotecan-induced diarrhea via down-regulation of intestinal pro-inflammatory cytokines and inhibition of intestinal epithelial apoptosis. | Toxicology and applied pharmacology 20061015 |
| Novel SN-38-incorporating polymeric micelles, NK012, eradicate vascular endothelial growth factor-secreting bulky tumors. | Cancer research 20061015 |
| Identification of gene polymorphisms of human DNA topoisomerase I in the National Cancer Institute panel of human tumour cell lines. | British journal of cancer 20061009 |
| High mortality from neo-adjuvant chemo-radiotherapy for rectal cancer needs to be evaluated against the alternative of adjuvant therapy. | British journal of cancer 20061009 |
| Optimal antidiarrhea treatment for antitumor agent irinotecan hydrochloride (CPT-11)-induced delayed diarrhea. | Cancer chemotherapy and pharmacology 20061001 |
| A mechanistic study on reduced toxicity of irinotecan by coadministered thalidomide, a tumor necrosis factor-alpha inhibitor. | The Journal of pharmacology and experimental therapeutics 20061001 |
| Inhibition of efflux transporter ABCG2/BCRP does not restore mitoxantrone sensitivity in irinotecan-selected human leukemia CPT-K5 cells: evidence for multifactorial multidrug resistance. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20061001 |
| Randomised study of sequential versus combination chemotherapy with capecitabine, irinotecan and oxaliplatin in advanced colorectal cancer, an interim safety analysis. A Dutch Colorectal Cancer Group (DCCG) phase III study. | Annals of oncology : official journal of the European Society for Medical Oncology 20061001 |
| Chemotherapy and regional therapy of hepatic colorectal metastases: expert consensus statement by Bartlett et al. | Annals of surgical oncology 20061001 |
| Chemotherapy and regional therapy of hepatic colorectal metastases: expert consensus statement. | Annals of surgical oncology 20061001 |
| Pharmacogenomics of colorectal cancer prevention and treatment. | Cancer investigation 20061001 |
| Topoisomerase I inhibitors: camptothecins and beyond. | Nature reviews. Cancer 20061001 |
| Uridine diphosphate glucuronosyltransferase (UGT) 1A1 and irinotecan: practical pharmacogenomics arrives in cancer therapy. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061001 |
| A pharmacokinetic-based test to prevent severe 5-fluorouracil toxicity. | Clinical pharmacology and therapeutics 20061001 |
| Effect of S-1 on pharmacokinetics of irinotecan in a patient with colorectal cancer. | Clinical pharmacology and therapeutics 20061001 |
| Targeting the lymphotoxin-beta receptor with agonist antibodies as a potential cancer therapy. | Cancer research 20061001 |
| Phase II study of 3-week scheduling of irinotecan in combination with cisplatin in patients with advanced nonsmall-cell lung cancer. | American journal of clinical oncology 20061001 |
| Docetaxel in the treatment of gastric cancer. | Future oncology (London, England) 20061001 |
| New drugs for the treatment of metastatic or refractory soft tissue sarcomas in children. | Future oncology (London, England) 20061001 |
| Challenges in the use of epidermal growth factor receptor inhibitors in colorectal cancer. | The oncologist 20061001 |
| Novel therapeutic developments other than EGFR and VEGF inhibition in colorectal cancer. | The oncologist 20061001 |
| Reversible posterior leukoencephalopathy syndrome after bevacizumab/FOLFIRI regimen for metastatic colon cancer. | Archives of neurology 20061001 |
| [A case of advanced gastric cancer with long-term survival treated by chemotherapy and surgical cytoreduction]. | Gan to kagaku ryoho. Cancer & chemotherapy 20061001 |
| [Case report of a liver metastasis from rectal cancer achieving complete response (CR) by a combination of intra-hepatic arterial infusion of irinotecan (CPT-11) with degradable starch microspheres (DSM) and weekly high-dose intra-hepatic arterial chemotherapy with 5-FU]. | Gan to kagaku ryoho. Cancer & chemotherapy 20061001 |
| [Colonic perforation in a patient treated with combination chemotherapy for recurrent ovarian clear cell adenocarcinoma]. | Gan to kagaku ryoho. Cancer & chemotherapy 20061001 |
| Cetuximab in the treatment of metastatic colorectal cancer: a model-based cost-effectiveness analysis. | Journal of chemotherapy (Florence, Italy) 20061001 |
| A prospective randomized study of irinotecan (CPT-11), leucovorin (LV) and 5-fluorouracil (5FU) versus leucovorin and 5-fluorouracil in patients with advanced colorectal carcinoma. | Journal of chemotherapy (Florence, Italy) 20061001 |
| Chemotherapeutic management of small bowel adenocarcinoma associated with Crohn's disease. | Journal of chemotherapy (Florence, Italy) 20061001 |
| Bevacizumab in the treatment of metastatic colorectal cancer (mCRC) in second- and third-line settings. | Seminars in oncology 20061001 |
| [Irinotecan plus cisplatin for the treatment of advanced non-small cell lung cancer]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20061001 |
| [Multicenter phase II study of modified FOLFIRI regimen in the advanced colorectal cancer patient refractory to fluoropyrimidine and oxaliplatin]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20061001 |
| [Application of monoclonal antibody in combination with irinotecan in the treatment of colorectal cancer]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20061001 |
| Phase II study of carboplatin, irinotecan, and thalidomide in patients with advanced non-small cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20061001 |
| Role of oxaliplatin combined with 5-fluorouracil and folinic acid in the first- and second-line treatment of advanced colorectal cancer. | Current oncology (Toronto, Ont.) 20061001 |
| CPT-11 and concomitant hyperfractionated accelerated radiotherapy induce efficient local control in rectal cancer patients: results from a phase II. | British journal of cancer 20060918 |
| Enhanced tumour antiangiogenic effects when combining gefitinib with the antivascular agent ZD6126. | British journal of cancer 20060918 |
| Induction cisplatin-irinotecan followed by concurrent cisplatin-irinotecan and radiotherapy without surgery in oesophageal cancer: multicenter phase II FFCD trial. | British journal of cancer 20060918 |
| Role for drug transporters beyond tumor resistance: hepatic functional imaging and genotyping of multidrug resistance transporters for the prediction of irinotecan toxicity. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060910 |
| Relationship of hepatic functional imaging to irinotecan pharmacokinetics and genetic parameters of drug elimination. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060910 |
| A phase I study of intravenous liposomal daunorubicin (DaunoXome) in paediatric patients with relapsed or resistant solid tumours. | British journal of cancer 20060904 |
| A multicenter phase III trial comparing irinotecan-gemcitabine (IG) with gemcitabine (G) monotherapy as first-line treatment in patients with locally advanced or metastatic pancreatic cancer. | British journal of cancer 20060904 |
| Pharmacokinetics and pharmacodynamics of irinotecan and its metabolites from plasma and saliva data in patients with metastatic digestive cancer receiving Folfiri regimen. | Cancer chemotherapy and pharmacology 20060901 |
| Cyclosporin A, tacrolimus and sirolimus are potent inhibitors of the human breast cancer resistance protein (ABCG2) and reverse resistance to mitoxantrone and topotecan. | Cancer chemotherapy and pharmacology 20060901 |
| Adjuvant therapy in colon cancer--what, when and how? | Annals of oncology : official journal of the European Society for Medical Oncology 20060901 |
| Effect of a novel vacuolar-H+-ATPase inhibitor on cell and tumor response to camptothecins. | The Journal of pharmacology and experimental therapeutics 20060901 |
| Phase II study of the CPT-11, mitoxantrone and dexamethasone regimen in combination with rituximab in elderly patients with relapsed diffuse large B-cell lymphoma. | Cancer science 20060901 |
| Emerging therapies for rectal cancer. | Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20060901 |
| A Phase II study of preoperative radiotherapy and concomitant weekly irinotecan in combination with protracted venous infusion 5-fluorouracil, for resectable locally advanced rectal cancer. | International journal of radiation oncology, biology, physics 20060901 |
| Phase II study of irinotecan plus cisplatin with concurrent radiotherapy for the patients with limited-disease small-cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20060901 |
| Potential application of GSTT1-null genotype in predicting toxicity associated to 5-fluouracil irinotecan and leucovorin regimen in advanced stage colorectal cancer patients. | Oncology reports 20060901 |
| Histone deacetylase inhibitor, trichostatin A, increases the chemosensitivity of anticancer drugs in gastric cancer cell lines. | Oncology reports 20060901 |
| Assessment of epidermal growth factor receptor (EGFR) expression in primary colorectal carcinomas and their related metastases on tissue sections and tissue microarray. | Virchows Archiv : an international journal of pathology 20060901 |
| Phase II study of combination chemotherapy with gemcitabine and irinotecan in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. | Japanese journal of clinical oncology 20060901 |
| A phase II study of high-dose bevacizumab in combination with irinotecan, 5-fluorouracil, leucovorin, as initial therapy for advanced colorectal cancer: results from the Eastern Cooperative Oncology Group study E2200. | Annals of oncology : official journal of the European Society for Medical Oncology 20060901 |
| Metastatic colorectal cancer: Therapeutic options. | Current treatment options in oncology 20060901 |
| Cancer of the gastroesophageal junction: Current therapy options. | Current treatment options in oncology 20060901 |
| Towards a pan-European consensus on the treatment of patients with colorectal liver metastases. | European journal of cancer (Oxford, England : 1990) 20060901 |
| Pharmacogenetics of SLCO1B1 gene and the impact of *1b and *15 haplotypes on irinotecan disposition in Asian cancer patients. | Pharmacogenetics and genomics 20060901 |
| A non-invasive method for detection of intestinal mucositis induced by different classes of chemotherapy drugs in the rat. | Cancer biology & therapy 20060901 |
| Biweekly oxaliplatin plus irinotecan and folinic acid-modulated 5-fluorouracil: a phase II study in pretreated patients with metastatic colorectal cancer. | Anti-cancer drugs 20060901 |
| Thymidine phosphorylase expression is associated with response to capecitabine plus irinotecan in patients with metastatic colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060901 |
| Pooled analysis of safety and efficacy of oxaliplatin plus fluorouracil/leucovorin administered bimonthly in elderly patients with colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060901 |
| [Pharmacokinetic study of cancer chemotherapy]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20060901 |
| Prophylaxis of irinotecan-induced diarrhea with neomycin and potential role for UGT1A1*28 genotype screening: a double-blind, randomized, placebo-controlled study. | The oncologist 20060901 |
| Systemic treatment of patients who have colorectal cancer and inflammatory bowel disease. | Gastroenterology clinics of North America 20060901 |
| [Malignant mesothelioma--diagnosis and treatment strategies]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060901 |
| [Hepatic arterial infusion chemotherapy for liver metastases from digestive cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060901 |
| [Evaluation of weekly low-dose CPT-11 combined with 5-FU/l-LV therapy for advanced and recurrent colorectal cancer--preliminary study]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060901 |
| [A case of non-curatively resected gastric cancer successfully treated over 17 months with TS-1 and irinotecan combination therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060901 |
| [A case of advanced gastric cancer with liver metastasis completely responding to CPT-11+low-dose 5-FU+CDDP chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060901 |
| [A case of non-curatively resected colon cancer with liver and lymph node metastases treated by TS-1/CPT-11 combination therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060901 |
| [A case of local recurrence of rectal cancer in long-term responding to combined therapy of low-dose CPT-11 and 5'-DFUR]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060901 |
| Hepatic transport, metabolism and biliary excretion of irinotecan in a cancer patient with an external bile drain. | Cancer biology & therapy 20060901 |
| Protocol consisting of cisplatin, etoposide and irinotecan induced complete pathological remission of primary small cell carcinoma of the bladder. | International journal of urology : official journal of the Japanese Urological Association 20060901 |
| Intracellular inhibition of carboxylesterases by benzil: modulation of CPT-11 cytotoxicity. | Molecular cancer therapeutics 20060901 |
| Highlights from: 42nd Annual Meeting of the American Society of Clinical Oncology. | Clinical colorectal cancer 20060901 |
| Phase I study of gefitinib plus FOLFIRI in previously untreated patients with metastatic colorectal cancer. | Clinical colorectal cancer 20060901 |
| [Application and recent research progress of irinotecan in treatment of advanced colorectal cancer]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20060901 |
| Angiogenesis in cancer. | Vascular health and risk management 20060901 |
| Temozolomide as prophylaxis for brain metastasis in non-small cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20060901 |
| Clinical pharmacokinetics of irinotecan-based chemotherapy in colorectal cancer patients. | Current clinical pharmacology 20060901 |
| Lung metastasis from an immature teratoma of the nasal cavity masquerading as small cell carcinoma of the lung. | Yonsei medical journal 20060831 |
| A phase II study of irinotecan plus cisplatin for patients with advanced stage IIIB or IV NSCLC previously treated with nonplatinum-based chemotherapy. | Cancer 20060815 |
| Hexosomes formed from glycerate surfactants--formulation as a colloidal carrier for irinotecan. | International journal of pharmaceutics 20060802 |
| [Follicular drug reaction from cetuximab: a common side effect in the treatment of metastatic colon carcinoma]. | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20060801 |
| A phase I and pharmacokinetic study of a powder-filled capsule formulation of oral irinotecan (CPT-11) given daily for 5 days every 3 weeks in patients with advanced solid tumors. | Cancer chemotherapy and pharmacology 20060801 |
| Heated intra-operative intraperitoneal oxaliplatin alone and in combination with intraperitoneal irinotecan: Pharmacologic studies. | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20060801 |
| Predicting the outcome of chemotherapy for colorectal cancer. | Current opinion in pharmacology 20060801 |
| Simultaneous chemoradiotherapy with irinotecan and cisplatin in limited disease small cell lung cancer: a phase I study. | Lung cancer (Amsterdam, Netherlands) 20060801 |
| First-line 5-fluorouracil/folinic acid, oxaliplatin and irinotecan (FOLFOXIRI) does not impair the feasibility and the activity of second line treatments in metastatic colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20060801 |
| Predictive value of D-dimer plasma levels in response and progressive disease in patients with lung cancer. | Lung cancer (Amsterdam, Netherlands) 20060801 |
| Determinants of chemosensitivity in gastric cancer. | Current opinion in pharmacology 20060801 |
| Exploiting the role of O6-methylguanine-DNA-methyltransferase (MGMT) in cancer therapy. | Current opinion in pharmacology 20060801 |
| A combination chemotherapy of carboplatin and irinotecan with granulocyte colony-stimulating factor (G-CSF) support in elderly patients with small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20060801 |
| Inhibition of poly(ADP-ribose) polymerase prevents irinotecan-induced intestinal damage and enhances irinotecan/temozolomide efficacy against colon carcinoma. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060801 |
| TPMT, UGT1A1 and DPYD: genotyping to ensure safer cancer therapy? | Trends in pharmacological sciences 20060801 |
| Growth inhibition and apoptosis induction in ovarian cancer cells. | International journal of oncology 20060801 |
| Response of heavily treated and relapsed hepatoblastoma in the transplanted liver to single-agent therapy with irinotecan. | Pediatric transplantation 20060801 |
| A photon counting technique for quantitatively evaluating progression of peritoneal tumor dissemination. | Cancer research 20060801 |
| In vitro drug response and molecular markers associated with drug resistance in malignant gliomas. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060801 |
| Growth-inhibitory effects of human anti-insulin-like growth factor-I receptor antibody (A12) in an orthotopic nude mouse model of anaplastic thyroid carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060801 |
| New agents, combinations, and opportunities in the treatment of advanced and early-stage colon cancer. | The Surgical clinics of North America 20060801 |
| [Lung cancer with bone metastasis]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060801 |
| [A case of pericardial tamponade caused by recurrent breast cancer treated with intrapericardial and intrapleural infusion of cisplatin (CDDP)]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060801 |
| [Multiple hepatic metastases of colon cancer responding to combined therapy with TS-1 and CPT-11--a case report]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060801 |
| Lack of usefulness of epidermal growth factor receptor expression determination for cetuximab therapy in patients with colorectal cancer. | Anti-cancer drugs 20060801 |
| Salvage chemotherapy with a combination of irinotecan hydrochloride and mitomycin C in elderly Japanese patients with gynecological malignancies: a pilot study. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20060801 |
| The role of targeted therapy in the treatment of colorectal cancer. | Clinical advances in hematology & oncology : H&O 20060801 |
| [Experimental study of effect of epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in combination with irinotecan]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20060801 |
| [Application of Camptosar in neoadjuvant chemotherapy for rectal cancer]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20060801 |
| Turning point for colorectal cancer clinical trials. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060720 |
| Randomized controlled trial of reduced-dose bolus fluorouracil plus leucovorin and irinotecan or infused fluorouracil plus leucovorin and oxaliplatin in patients with previously untreated metastatic colorectal cancer: a North American Intergroup Trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060720 |
| Phase II multicenter trial of bevacizumab plus fluorouracil and leucovorin in patients with advanced refractory colorectal cancer: an NCI Treatment Referral Center Trial TRC-0301. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060720 |
| Pooled analysis of phase II window studies in children with contemporary high-risk metastatic rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060720 |
| Inhibition of insulin receptor isoform-A signalling restores sensitivity to gefitinib in previously de novo resistant colon cancer cells. | British journal of cancer 20060717 |
| Management of advanced colorectal cancer: state of the art. | British journal of cancer 20060717 |
| Enhanced antitumor efficacy of telomerase-selective oncolytic adenoviral agent OBP-401 with docetaxel: preclinical evaluation of chemovirotherapy. | International journal of cancer 20060715 |
| Review of capecitabine as oral treatment of gastric, gastroesophageal, and esophageal cancers. | Cancer 20060715 |
| Pancreatic cancer: highlights from the 42nd annual meeting of the American Society of Clinical Oncology, 2006. | JOP : Journal of the pancreas 20060710 |
| The role of haemoglobin level in predicting the response to first-line chemotherapy in advanced colorectal cancer patients. | British journal of cancer 20060703 |
| The clinical and economic benefits of capecitabine and tegafur with uracil in metastatic colorectal cancer. | British journal of cancer 20060703 |
| Novel fluoro-substituted camptothecins: in vivo antitumor activity, reduced gastrointestinal toxicity and pharmacokinetic characterization. | Cancer chemotherapy and pharmacology 20060701 |
| The novel UGT1A9 intronic I399 polymorphism appears as a predictor of 7-ethyl-10-hydroxycamptothecin glucuronidation levels in the liver. | Drug metabolism and disposition: the biological fate of chemicals 20060701 |
| A phase I dose-finding clinical pharmacokinetic study of an oral formulation of irinotecan (CPT-11) administered for 5 days every 3 weeks in patients with advanced solid tumours. | Annals of oncology : official journal of the European Society for Medical Oncology 20060701 |
| Functional validation of the genetic polymorphisms of human ATP-binding cassette (ABC) transporter ABCG2: identification of alleles that are defective in porphyrin transport. | Molecular pharmacology 20060701 |
| Salvage chemotherapy with CPT-11 for recurrent meningioma. | Journal of neuro-oncology 20060701 |
| Effects of different combinations of gefitinib and irinotecan in lung cancer cell lines expressing wild or deletional EGFR. | Lung cancer (Amsterdam, Netherlands) 20060701 |
| Irinotecan-eluting stents inhibited neointimal proliferation in hypercholesterolemic rabbit aortas. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060701 |
| Biological agents versus chemotherapy in the treatment of colorectal cancer. | Expert opinion on pharmacotherapy 20060701 |
| The role of UGT1A1*28 polymorphism in the pharmacodynamics and pharmacokinetics of irinotecan in patients with metastatic colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060701 |
| Screening for adverse reactions to irinotecan treatment using the Invader UGT1A1 Molecular Assay. | Expert review of molecular diagnostics 20060701 |
| [Capecitabine]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060701 |
| [Current evidence of irinotecan combination chemotherapy with TS-1 in patients with advanced colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060701 |
| [24 hour infusion of CPT-11/oral UFT/LV]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060701 |
| [IFL]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060701 |
| [A case of inoperable gastric small cell carcinoma effectively treated by chemotherapy and radiotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060701 |
| The in vitro metabolism of irinotecan (CPT-11) by carboxylesterase and beta-glucuronidase in human colorectal tumours. | British journal of clinical pharmacology 20060701 |
| [Adjuvant treatment of colorectal cancer]. | Bulletin du cancer 20060701 |
| The effects of the oral, pan-VEGF-R kinase inhibitor CEP-7055 and chemotherapy in orthotopic models of glioblastoma and colon carcinoma in mice. | Molecular cancer therapeutics 20060701 |
| Ratiometric dosing of anticancer drug combinations: controlling drug ratios after systemic administration regulates therapeutic activity in tumor-bearing mice. | Molecular cancer therapeutics 20060701 |
| Role of panitumumab in the management of metastatic colorectal cancer. | Clinical colorectal cancer 20060701 |
| [Present status and prospect of irinotecan application in adjuvant therapy for colorectal cancer]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20060701 |
| Second-line treatment of small-cell lung cancer. | Current oncology reports 20060701 |
| Novel therapeutic approaches in pediatric and young adult sarcomas. | Current oncology reports 20060701 |
| Reduced tau expression in gastric cancer can identify candidates for successful Paclitaxel treatment. | British journal of cancer 20060619 |
| Biweekly oxaliplatin, raltitrexed, 5-fluorouracil and folinic acid combination chemotherapy during preoperative radiation therapy for locally advanced rectal cancer: a phase I-II study. | British journal of cancer 20060619 |
| Different susceptibility of osteosarcoma cell lines and primary cells to treatment with oncolytic adenovirus and doxorubicin or cisplatin. | British journal of cancer 20060619 |
| Phase I/II study of docetaxel and S-1 in patients with advanced gastric cancer. | British journal of cancer 20060619 |
| Microvessel density and VEGF expression are prognostic factors in colorectal cancer. Meta-analysis of the literature. | British journal of cancer 20060619 |
| Dose-finding phase I clinical and pharmacokinetic study of orally administered irinotecan in patients with advanced solid tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060615 |
| Phase 1 and pharmacokinetic study of intravenous irinotecan in refractory solid tumor patients with hepatic dysfunction. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060615 |
| Vascular endothelial growth factor receptor-1 mediates migration of human colorectal carcinoma cells by activation of Src family kinases. | British journal of cancer 20060605 |
| Phase 1 trial of the antiangiogenic peptide ATN-161 (Ac-PHSCN-NH(2)), a beta integrin antagonist, in patients with solid tumours. | British journal of cancer 20060605 |
| Methylenetetrahydrofolate reductase gene polymorphisms: genomic predictors of clinical response to fluoropyrimidine-based chemotherapy? | Cancer chemotherapy and pharmacology 20060601 |
| Secondary acute promyelocytic leukemia following irinotecan and oxaliplatin for advanced colon cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20060601 |
| Small cell carcinoma of the larynx treated with irinotecan and cisplatin. | Auris, nasus, larynx 20060601 |
| Immunotherapy with dendritic cells and CpG oligonucleotides can be combined with chemotherapy without loss of efficacy in a mouse model of colon cancer. | International journal of cancer 20060601 |
| Economic impact of simplified de Gramont regimen in first-line therapy in metastatic colorectal cancer. | The European journal of health economics : HEPAC : health economics in prevention and care 20060601 |
| Expression of drug pathway proteins is independent of tumour type. | The Journal of pathology 20060601 |
| Trichostatin A enhances the response of chemotherapeutic agents in inhibiting pancreatic cancer cell proliferation. | Virchows Archiv : an international journal of pathology 20060601 |
| Phase II study of combination therapy with S-1 and irinotecan in patients with advanced colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20060601 |
| In vitro sensitivity to platinum-derived drugs is associated with expression of thymidylate synthase and dihydropyrimidine dehydrogenase in human lung cancer. | Oncology reports 20060601 |
| Resin 90Y-microsphere brachytherapy for unresectable colorectal liver metastases: modern USA experience. | International journal of radiation oncology, biology, physics 20060601 |
| Gene expression analysis using human cancer xenografts to identify novel predictive marker genes for the efficacy of 5-fluorouracil-based drugs. | Cancer science 20060601 |
| Inhibition of glutathione synthesis overcomes Bcl-2-mediated topoisomerase inhibitor resistance and induces nonapoptotic cell death via mitochondrial-independent pathway. | Cancer research 20060601 |
| Natural history and chemotherapy effectiveness for advanced adenocarcinoma of the small bowel: a retrospective review of 113 cases. | American journal of clinical oncology 20060601 |
| FOLFIRI with or without celecoxib in advanced colorectal cancer: a randomized phase II study of the Gruppo Oncologico dell'Italia Meridionale (GOIM). | Annals of oncology : official journal of the European Society for Medical Oncology 20060601 |
| Cetuximab for treatment of metastatic colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20060601 |
| First- and second-line therapy of metastatic colorectal cancer. | Expert review of anticancer therapy 20060601 |
| Bevacizumab: new drug. Metastatic colorectal cancer: good in theory, not in practice. | Prescrire international 20060601 |
| [Complete response to CPT-11 and UFT/LV combination therapy in a case with simultaneous multiple lung metastases from colon cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060601 |
| [A patient with hepatic, pulmonary, and nodal metastases of colon cancer responding to CPT-11/TS-1 therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060601 |
| [Advanced rectal cancer in an older patient, in whom metastatic liver lesions were effectively controlled with oral UFT+LV and venous CPT-11 administration--case report]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060601 |
| [Collision cancer of squamous cell carcinoma and small cell carcinoma of the lung; report of a case]. | Kyobu geka. The Japanese journal of thoracic surgery 20060601 |
| Epidermal growth factor receptor tyrosine kinase inhibitors: present and future role in gastrointestinal cancer treatment: a review. | The oncologist 20060601 |
| Development of an etoposide prodrug for dual prodrug-enzyme antitumor therapy. | Molecular cancer therapeutics 20060601 |
| A phase II trial of irinotecan and cisplatin in patients with metastatic neuroendocrine tumors. | Digestive diseases and sciences 20060601 |
| [S-1 for gastric cancer-S-1 monotherapy and its progress]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060601 |
| [Clinical development of S-1 (TS-1) for advanced gastric cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060601 |
| [Irinotecan plus oral S-1 in patients with advanced gastric cancer-biweekly IRIS regimen]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060601 |
| [Combination chemotherapy of S-1 +CPT-11 (q 4-5 w) for metastatic gastric cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060601 |
| [S-1 as a single agent for colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060601 |
| [The current evidence of S-1 and irinotecan hydrochloride combination chemotherapy with tri-weekly schedule]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060601 |
| [Irinotecan plus oral S-1 in patients with advanced colorectal cancer--biweekly IRIS regimen]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060601 |
| [Combination chemotherapy with S-1 plus CPT-11 for patients with advanced or recurrent colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060601 |
| [Long-term repeatable chemotherapy for patients with advanced pancreatic cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060601 |
| Pancreatic metastasis and obstructive jaundice in small cell lung carcinoma. | The Korean journal of internal medicine 20060601 |
| Clinical implications of angiogenesis in cancers. | Vascular health and risk management 20060601 |
| A pilot study of cisplatin, irinotecan, leucovorin and 5-fluorouracil (PILF) combination chemotherapy for advanced gastric cancer. | Cancer research and treatment : official journal of Korean Cancer Association 20060601 |
| Pleiotrophin, a candidate gene for poor tumor vasculature and in vivo neuroblastoma sensitivity to irinotecan. | Oncogene 20060525 |
| Phase II study of docetaxel and irinotecan combination chemotherapy in metastatic gastric carcinoma. | British journal of cancer 20060522 |
| Clear cell carcinoma of the ovary: a retrospective multicentre experience of 254 patients with complete surgical staging. | British journal of cancer 20060522 |
| Vinflunine -- an active chemotherapy for treatment of advanced non-small-cell lung cancer previously treated with a platinum-based regimen: results of a phase II study. | British journal of cancer 20060522 |
| Phase II study of capecitabine and irinotecan combination chemotherapy in patients with advanced gastric cancer. | British journal of cancer 20060522 |
| Irinogenetics: what is the right star? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060520 |
| Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060520 |
| Neuroblastoma cell death in response to docosahexaenoic acid: sensitization to chemotherapy and arsenic-induced oxidative stress. | International journal of cancer 20060515 |
| Phase II trial of combined irinotecan and oxaliplatin given every 3 weeks to patients with metastatic colorectal cancer. | Cancer 20060515 |
| Interpreting disparate responses to cancer therapy: the role of human population genetics. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060510 |
| The place of VEGF inhibition in the current management of renal cell carcinoma. | British journal of cancer 20060508 |
| A phase II study of FOLFIRI-3 (double infusion of irinotecan combined with LV5FU) after FOLFOX in advanced colorectal cancer patients. | British journal of cancer 20060508 |
| A phase I and II study of 2-weekly irinotecan with capecitabine in advanced gastroesophageal adenocarcinoma. | British journal of cancer 20060508 |
| Phase II study of irinotecan combined with carboplatin in previously untreated small-cell lung cancer. | British journal of cancer 20060508 |
| Invader UGT1A1 molecular assay for irinotecan toxicity. A genetic test for an increased risk of toxicity from the cancer chemotherapy drug irinotecan (Camptosar). | The Medical letter on drugs and therapeutics 20060508 |
| HPLC method for determination of SN-38 content and SN-38 entrapment efficiency in a novel liposome-based formulation, LE-SN38. | Journal of pharmaceutical and biomedical analysis 20060503 |
| Phase I and pharmacokinetic study of docetaxel, irinotecan, and celecoxib in patients with advanced non-small cell lung cancer. | Investigational new drugs 20060501 |
| Overexpression of thymosin beta-4 renders SW480 colon carcinoma cells more resistant to apoptosis triggered by FasL and two topoisomerase II inhibitors via downregulating Fas and upregulating Survivin expression, respectively. | Carcinogenesis 20060501 |
| Growth inhibition of orthotopic anaplastic thyroid carcinoma xenografts in nude mice by PTK787/ZK222584 and CPT-11. | Head & neck 20060501 |
| Bcr-abl positive blast crisis of chronic myeloid leukemia emerging in a case of metastatic colorectal cancer 3 months after completion of an 8-month course of cetuximab and irinotecan. | European journal of haematology 20060501 |
| Angiogenesis modifications related with cetuximab plus irinotecan as anticancer treatment in advanced colorectal cancer patients. | Annals of oncology : official journal of the European Society for Medical Oncology 20060501 |
| Treatment of hepatic metastases from colorectal cancer: many doubts, some certainties. | Cancer treatment reviews 20060501 |
| Increased tolerability of bimonthly 12-hour timed flat infusion 5-fluorouracil/irinotecan regimen in advanced colorectal cancer: A dose-finding study. | Oncology reports 20060501 |
| Multimodality treatment of esophageal cancer: a review of the current status and future directions. | Current oncology reports 20060501 |
| Individualizing chemotherapeutic treatment of colorectal cancer. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20060501 |
| Evolving role of antineoplastic agents in colorectal cancer. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20060501 |
| Randomized phase III trial comparing irinotecan/cisplatin with etoposide/cisplatin in patients with previously untreated extensive-stage disease small-cell lung cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060501 |
| Chemotherapy regimen predicts steatohepatitis and an increase in 90-day mortality after surgery for hepatic colorectal metastases. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060501 |
| Antitumor efficacy of edotecarin as a single agent and in combination with chemotherapy agents in a xenograft model. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060501 |
| [The present state and future of home care for gastric cancer patients]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060501 |
| [Lung carcinoma]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060501 |
| [Outpatient based colorectal cancer treatment--the current status, challenges and future outlook]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060501 |
| [Comparison of ramosetron and azasetron for prevention of acute and delayed cisplatin-induced emesis in lung cancer patients]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060501 |
| [A case of gastric cancer presenting with obstructive jaundice and responding to biweekly CPT-11 and CDDP combination administration]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060501 |
| [Development of acute type, CD 8 positive adult T-cell leukemia in a carrier of hepatitis B virus--possible therapeutic effect of lamivudine combined with chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060501 |
| Pharmacokinetic mechanisms for reduced toxicity of irinotecan by coadministered thalidomide. | Current drug metabolism 20060501 |
| Optimal treatment of metastatic colorectal cancer. | Expert review of anticancer therapy 20060501 |
| [Efficacy of Avastin in combination with irinotecan for metastatic colorectal cancer]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20060501 |
| [Irinotecan for the treatment of metastatic colorectal cancer]. | Bulletin du cancer 20060501 |
| Targeted agents for adjuvant therapy of colon cancer. | Clinical colorectal cancer 20060501 |
| First line chemotherapy in advanced or metastatic NSCLC. | Annals of oncology : official journal of the European Society for Medical Oncology 20060501 |
| Chemotherapy advances in small cell lung cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20060501 |
| [Palliative chemotherapy and CUP-syndrome: medical intentions versus patients' attitudes in decision making]. | Wiener medizinische Wochenschrift (1946) 20060501 |
| Monoclonal antibodies against epidermal growth factor receptor in advanced colorectal carcinoma: clinical efficacy and markers of sensitivity. | Reviews on recent clinical trials 20060501 |
| Mutational studies of G553 in TM5 of ABCG2: a residue potentially involved in dimerization. | Biochemistry 20060425 |
| MRI in patients with high-grade gliomas treated with bevacizumab and chemotherapy. | Neurology 20060425 |
| Phase I/II study of S-1 combined with irinotecan for metastatic advanced gastric cancer. | British journal of cancer 20060424 |
| Phase II study of erlotinib (OSI-774) in patients with metastatic colorectal cancer. | British journal of cancer 20060424 |
| Gastrazole (JB95008), a novel CCK2/gastrin receptor antagonist, in the treatment of advanced pancreatic cancer: results from two randomised controlled trials. | British journal of cancer 20060424 |
| HER2 expression as a potential marker for response to therapy targeted to the EGFR. | British journal of cancer 20060424 |
| Potentiation of irinotecan sensitivity by Se-methylselenocysteine in an in vivo tumor model is associated with downregulation of cyclooxygenase-2, inducible nitric oxide synthase, and hypoxia-inducible factor 1alpha expression, resulting in reduced angiogenesis. | Oncogene 20060420 |
| Phase II study of capecitabine, oxaliplatin, and erlotinib in previously treated patients with metastastic colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060420 |
| New issues on cetuximab mechanism of action in epidermal growth factor receptor-negative colorectal cancer: the role of vascular endothelial growth factor. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060420 |
| Preclinical differentiation between apparently safe and potentially hepatotoxic applications of TRAIL either alone or in combination with chemotherapeutic drugs. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060415 |
| Circadian regulation of mouse topoisomerase I gene expression by glucocorticoid hormones. | Biochemical pharmacology 20060414 |
| Surgical resection of hepatic metastases from colorectal cancer: a systematic review of published studies. | British journal of cancer 20060410 |
| Concurrent chemoradiation with capecitabine and weekly irinotecan as preoperative treatment for rectal cancer: results from a phase I/II study. | British journal of cancer 20060410 |
| A phase II study of fixed-dose capecitabine and assessment of predictors of toxicity in patients with advanced/metastatic colorectal cancer. | British journal of cancer 20060410 |
| XELOX (capecitabine plus oxaliplatin) as first-line treatment for elderly patients over 70 years of age with advanced colorectal cancer. | British journal of cancer 20060410 |
| A randomized phase II trial of irinotecan plus carboplatin versus etoposide plus carboplatin treatment in patients with extended disease small-cell lung cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20060401 |
| Phase II study of irinotecan and docetaxel in patients with previously treated non-small cell lung cancer: an Alpe-Adria Thoracic Oncology Multidisciplinary group study (ATOM 007). | Lung cancer (Amsterdam, Netherlands) 20060401 |
| The antitumor effect of a novel differentiation inducer, 2, 2-Bis (4-(4-amino-3-hydroxyphenoxy) phenyl) adamantane (DPA), in combinatory therapy on human colon cancer. | International journal of oncology 20060401 |
| The combination effect of amrubicin with cisplatin or irinotecan for small-cell lung cancer cells. | Oncology reports 20060401 |
| Optimal combination chemotherapy and chemoradiotherapy with etoposide for advanced cervical squamous cancer cells in vitro. | Oncology reports 20060401 |
| A phase 2 trial of irinotecan (CPT-11) in patients with recurrent malignant glioma: a North American Brain Tumor Consortium study. | Neuro-oncology 20060401 |
| Chemotherapy for advanced pancreatic cancer. | Best practice & research. Clinical gastroenterology 20060401 |
| Irinotecan, oxaliplatin and raltitrexed for the treatment of advanced colorectal cancer. | Expert opinion on pharmacotherapy 20060401 |
| Phase I/pilot study of SU5416 (semaxinib) in combination with irinotecan/bolus 5-FU/LV (IFL) in patients with metastatic colorectal cancer. | American journal of clinical oncology 20060401 |
| Phase II trial of gemcitabine plus irinotecan in patients with esophageal cancer: a Southwest Oncology Group (SWOG) trial. | American journal of clinical oncology 20060401 |
| [A case of gastric cancer with multiple liver metastases resistant to TS-1 responding to chemotherapy with paclitaxel plus doxifluridine]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060401 |
| Postchemotherapy characteristics of hepatic colorectal metastases: remnants of uncertain malignant potential. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20060401 |
| [Non-surgical treatment for pancreatic cancer]. | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20060401 |
| [Chemotherapy in rectal cancer]. | The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20060401 |
| [A case report: simultaneous bilateral testicular tumors with different cell types--complete response after combination chemotherapy of cisplatin and irrinotecan hydrochloride--]. | Hinyokika kiyo. Acta urologica Japonica 20060401 |
| [Prevention of anticancer drug-induced premature ovarian failure]. | Nihon rinsho. Japanese journal of clinical medicine 20060401 |
| [Molecular targets in colon cancer]. | Therapeutische Umschau. Revue therapeutique 20060401 |
| Genetic variation and haplotype structure of the ABC transporter gene ABCG2 in a Japanese population. | Drug metabolism and pharmacokinetics 20060401 |
| Individualizing cancer chemotherapy. | Clinical advances in hematology & oncology : H&O 20060401 |
| Anti-EGFR therapies: clinical experience in colorectal, lung, and head and neck cancers. | Oncology (Williston Park, N.Y.) 20060401 |
| Nondermatologic adverse events associated with anti-EGFR therapy. | Oncology (Williston Park, N.Y.) 20060401 |
| Adjuvant therapy for colorectal cancer: yesterday, today, and tomorrow. | Oncology (Williston Park, N.Y.) 20060401 |
| A phase II study of irinotecan, 5-fluorouracil and leucovorin for treatment in patients with previously untreated advanced colorectal cancer. | Cancer research and treatment : official journal of Korean Cancer Association 20060401 |
| DNA damage-induced expression of p53 suppresses mitotic checkpoint kinase hMps1: the lack of this suppression in p53MUT cells contributes to apoptosis. | The Journal of biological chemistry 20060331 |
| MDR- and CYP3A4-mediated drug-herbal interactions. | Life sciences 20060327 |
| Capecitabine and mitomycin C in patients with metastatic colorectal cancer resistant to fluorouracil and irinotecan. | British journal of cancer 20060327 |
| Raltitrexed-eloxatin salvage chemotherapy in gemcitabine-resistant metastatic pancreatic cancer. | British journal of cancer 20060327 |
| Cetuximab and irinotecan as third-line therapy in advanced colorectal cancer patients: a single centre phase II trial. | British journal of cancer 20060327 |
| FOLFOXIRI (folinic acid, 5-fluorouracil, oxaliplatin and irinotecan) vs FOLFIRI (folinic acid, 5-fluorouracil and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): a multicentre randomised phase III trial from the Hellenic Oncology Research Group (HORG). | British journal of cancer 20060327 |
| Development of a highly active nanoliposomal irinotecan using a novel intraliposomal stabilization strategy. | Cancer research 20060315 |
| From bedside to bench to bedside to clinical practice: an odyssey with irinotecan. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060315 |
| Irinotecan inactivation is modulated by epigenetic silencing of UGT1A1 in colon cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060315 |
| Correspondence re: Cecchin et al., Carboxylesterase isoform 2 mRNA expression in peripheral blood mononuclear cells is a predictive marker of the irinotecan to SN38 activation step in colorectal cancer patients. Clin Cancer Res 2005;11:6901-7. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060315 |
| Concurrent chemotherapy (carboplatin, paclitaxel, etoposide) and involved-field radiotherapy in limited stage small cell lung cancer: a Dutch multicenter phase II study. | British journal of cancer 20060313 |
| [Adjuvant and palliative chemotherapy of colorectal cancer in Germany outside controlled trials]. | Deutsche medizinische Wochenschrift (1946) 20060310 |
| Role of pharmacogenetics in irinotecan therapy. | Cancer letters 20060308 |
| [The modern treatment of colorectal cancer. Present and future]. | Orvosi hetilap 20060305 |
| Irinotecan (CPT-11) combined with cisplatin for small cell carcinoma of the nasal cavity. | Auris, nasus, larynx 20060301 |
| Lack of response of cetuximab plus oxaliplatin in advanced colorectal cancer patients resistant to both oxaliplatin and cetuximab plus irinotecan. | Annals of oncology : official journal of the European Society for Medical Oncology 20060301 |
| Investigation of clinical and dosimetric factors associated with postoperative pulmonary complications in esophageal cancer patients treated with concurrent chemoradiotherapy followed by surgery. | International journal of radiation oncology, biology, physics 20060301 |
| Pharmacogenetics of irinotecan metabolism and transport: an update. | Toxicology in vitro : an international journal published in association with BIBRA 20060301 |
| Cetuximab and irinotecan/5-fluorouracil/folinic acid is a safe combination for the first-line treatment of patients with epidermal growth factor receptor expressing metastatic colorectal carcinoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20060301 |
| Recent developments in the use of chemotherapy in brain tumours. | European journal of cancer (Oxford, England : 1990) 20060301 |
| Irinotecan as first-line chemotherapy in patients with advanced hepatocellular carcinoma: a multicenter phase II study with dose adjustment according to baseline serum bilirubin level. | European journal of cancer (Oxford, England : 1990) 20060301 |
| Uridine diphosphate glucuronosyl transferase 1A1 promoter polymorphism predicts the risk of gastrointestinal toxicity and fatigue induced by irinotecan-based chemotherapy. | Cancer 20060301 |
| Direct activation of the human major vault protein gene by DNA-damaging agents. | Oncology reports 20060301 |
| Hyperforin in St. John's wort drug interactions. | European journal of clinical pharmacology 20060301 |
| The integration of oral capecitabine into chemoradiation regimens for locally advanced rectal cancer: how successful have we been? | Annals of oncology : official journal of the European Society for Medical Oncology 20060301 |
| Irinotecan in the treatment of small cell lung cancer: a review of patient safety considerations. | Expert opinion on drug safety 20060301 |
| Novel nanoliposomal CPT-11 infused by convection-enhanced delivery in intracranial tumors: pharmacology and efficacy. | Cancer research 20060301 |
| Rapid identification of three functionally relevant polymorphisms in the OATP1B1 transporter gene using Pyrosequencing. | Pharmacogenomics 20060301 |
| [A case of small-cell lung cancer responding remarkably to CPT-11 and CDDP combination chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060301 |
| [A case of small-cell lung cancer effectively treated by bi-weekly administration of amrubicin]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060301 |
| Phase II trial alternating FOLFOX-6 and FOLFIRI regimens in second-line therapy of patients with metastatic colorectal cancer (FIREFOX study). | Cancer investigation 20060301 |
| [Chemotherapy for lung cancer patients]. | Journal of UOEH 20060301 |
| Role of ABCG2 as a biomarker for predicting resistance to CPT-11/SN-38 in lung cancer. | Cancer science 20060301 |
| Novel missense mutation of the DNA topoisomerase I gene in SN-38-resistant DLD-1 cells. | Molecular cancer therapeutics 20060301 |
| Small cell lung cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20060301 |
| Neoadjuvant treatment of unresectable liver metastases from colorectal cancer. | Clinical colorectal cancer 20060301 |
| Efficacy and safety of cetuximab/irinotecan in chemotherapy-refractory metastatic colorectal adenocarcinomas: a clinical practice setting, multicenter experience. | Clinical colorectal cancer 20060301 |
| Multicenter phase II study of fixed sequences of capecitabine combined with oxaliplatin or irinotecan in patients with previously untreated metastatic colorectal cancer. | Clinical colorectal cancer 20060301 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20060301 |
| Randomized phase III trial of cisplatin/irinotecan versus cisplatin/etoposide in patients with extensive-stage small-cell lung cancer. | Clinical lung cancer 20060301 |
| Tumour regression and mesorectal lymph node changes after intensified neoadjuvant chemoradiation for carcinoma of the rectum. | APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20060301 |
| Prevention of irinotecan associated diarrhea by intestinal alkalization. A pilot study in gastrointestinal cancer patients. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20060301 |
| Irinotecan for children with relapsed solid tumors. | Pediatric hematology and oncology 20060301 |
| Phase I and pharmacokinetic study of combination chemotherapy using irinotecan and paclitaxel in patients with lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20060301 |
| Phase II trial of temozolomide and irinotecan as second-line treatment for advanced non-small cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20060301 |
| Renal cell carcinoma and the use of sorafenib. | Therapeutics and clinical risk management 20060301 |
| Synergistic effects of protein tyrosine kinase inhibitor genistein with camptothecins against three cell lines in vitro. | Cancer letters 20060227 |
| Gemcitabine and oxaliplatin (GEMOX) in gemcitabine refractory advanced pancreatic adenocarcinoma: a phase II study. | British journal of cancer 20060227 |
| Targeting insulin-like growth factor pathways. | British journal of cancer 20060227 |
| Lyotropic liquid crystalline phases formed from glycerate surfactants as sustained release drug delivery systems. | International journal of pharmaceutics 20060217 |
| Randomized Phase II study of two opposite administration sequences of irinotecan and cisplatin in patients with advanced nonsmall cell lung carcinoma. | Cancer 20060215 |
| A phase I and pharmacokinetic study of fixed-dose selenomethionine and irinotecan in solid tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060215 |
| Intestinal microflora and digestive toxicity of irinotecan in mice. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060215 |
| [Recent progress in the treatment of colorectal cancer]. | Medizinische Klinik (Munich, Germany : 1983) 20060215 |
| Neoadjuvant chemotherapy prior to preoperative chemoradiation or radiation in rectal cancer: should we be more cautious? | British journal of cancer 20060213 |
| Association of activated transcription factor nuclear factor kappab with chemoradiation resistance and poor outcome in esophageal carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060210 |
| c-FLIP inhibits chemotherapy-induced colorectal cancer cell death. | Oncogene 20060209 |
| A pilot study on the safety of combining chrysin, a non-absorbable inducer of UGT1A1, and irinotecan (CPT-11) to treat metastatic colorectal cancer. | Cancer chemotherapy and pharmacology 20060201 |
| Temozolomide after radiotherapy for newly diagnosed high-grade glioma and unfavorable low-grade glioma in children. | Journal of neuro-oncology 20060201 |
| Long-term outcome of concurrent chemotherapy and reirradiation for recurrent and second primary head-and-neck squamous cell carcinoma. | International journal of radiation oncology, biology, physics 20060201 |
| Short-time infusion of oxaliplatin in combination with capecitabine (XELOX30) as second-line therapy in patients with advanced colorectal cancer after failure to irinotecan and 5-fluorouracil. | Annals of oncology : official journal of the European Society for Medical Oncology 20060201 |
| The safety and efficacy of the weekly dosing of irinotecan for platinum- and taxanes-resistant epithelial ovarian cancer. | Gynecologic oncology 20060201 |
| A phase I, pharmacokinetic and biologic correlative study of oblimersen sodium (Genasense, G3139) and irinotecan in patients with metastatic colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20060201 |
| Phase II study of a protracted irinotecan schedule in children with refractory or recurrent soft tissue sarcoma. | Cancer 20060201 |
| in vitro synergistic antitumor activity of a combination of 5-fluorouracil and irinotecan in human colon cancer. | International journal of oncology 20060201 |
| Current status of cetuximab for the treatment of patients with solid tumors. | The Annals of pharmacotherapy 20060201 |
| PET/CT in the evaluation of response to treatment of liver metastases from colorectal cancer with bevacizumab and irinotecan. | Technology in cancer research & treatment 20060201 |
| Study of the genetic determinants of UGT1A1 inducibility by phenobarbital in cultured human hepatocytes. | Pharmacogenetics and genomics 20060201 |
| Recent developments in the systemic therapy of advanced gastroesophageal malignancies. | Expert opinion on investigational drugs 20060201 |
| Identification and immunotherapeutic targeting of antigens induced by chemotherapy. | Nature biotechnology 20060201 |
| Cefixime allows greater dose escalation of oral irinotecan: a phase I study in pediatric patients with refractory solid tumors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060201 |
| Randomized phase II study of neoadjuvant combined-modality chemoradiation for distal rectal cancer: Radiation Therapy Oncology Group Trial 0012. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060201 |
| A Phase I study of escalating doses of the tyrosine kinase inhibitor semaxanib (SU5416) in combination with irinotecan in patients with advanced colorectal carcinoma. | Japanese journal of clinical oncology 20060201 |
| Central nervous system toxicity induced by irinotecan. | Journal of the National Cancer Institute 20060201 |
| Transarterial chemoembolization with degradable starch microspheres, irinotecan, and mitomycin-C in patients with liver metastases. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20060201 |
| Irinotecan, oxaliplatin plus bolus 5-fluorouracil and low dose folinic acid every 2 weeks: a feasibility study in metastatic colorectal cancer patients. | American journal of clinical oncology 20060201 |
| Designer combination therapy for cancer. | Nature biotechnology 20060201 |
| Changing paradigms--an update on the multidisciplinary management of malignant glioma. | The oncologist 20060201 |
| [Reflexion on a good strategy of use of oxaliplatine with 5-fluorouracil and its derivatives in patients with advanced colorectal cancer]. | Bulletin du cancer 20060201 |
| [Progress in therapy for testicular tumors]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060201 |
| [A case of gastric cancer with peritoneal dissemination who achieved five-year survival by successive treatments with TS-1 alone and in combination with other drugs]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060201 |
| The cardenolide UNBS1450 is able to deactivate nuclear factor kappaB-mediated cytoprotective effects in human non-small cell lung cancer cells. | Molecular cancer therapeutics 20060201 |
| [Mechanisms of substrate transport by ABC transporter, MRP1/ABCC1]. | Seikagaku. The Journal of Japanese Biochemical Society 20060201 |
| Novel single nucleotide polymorphism of UGT1A7 gene in Japanese. | Drug metabolism and pharmacokinetics 20060201 |
| Novel single nucleotide polymorphism of UGT1A9 gene in Japanese. | Drug metabolism and pharmacokinetics 20060201 |
| [Treatment of colorectal cancer liver metastases]. | Minerva medica 20060201 |
| Administration of anti-EGFR therapy: a practical review. | Seminars in oncology nursing 20060201 |
| [Is small cell lung cancer an orphan disease?]. | Revue de pneumologie clinique 20060201 |
| [From ASCO and WCLC 2005 to clinical practice: 'conventional' treatments]. | Revue de pneumologie clinique 20060201 |
| Targeted therapy in colorectal cancer. | Clinical advances in hematology & oncology : H&O 20060201 |
| Natural health products that inhibit angiogenesis: a potential source for investigational new agents to treat cancer-Part 1. | Current oncology (Toronto, Ont.) 20060201 |
| Polymorphisms of glutathione S-transferases (GST) and thymidylate synthase (TS)--novel predictors for response and survival in gastric cancer patients. | British journal of cancer 20060130 |
| Adrenomedullin and tumour angiogenesis. | British journal of cancer 20060116 |
| SCOTROC 2B: feasibility of carboplatin followed by docetaxel or docetaxel-irinotecan as first-line therapy for ovarian cancer. | British journal of cancer 20060116 |
| 'A phase II study of oral uracil/ftorafur (UFT) plus leucovorin combined with oxaliplatin (TEGAFOX) as first-line treatment in patients with metastatic colorectal cancer'. | British journal of cancer 20060116 |
| Phase I studies of imatinib mesylate combined with cisplatin and irinotecan in patients with small cell lung carcinoma. | Cancer 20060115 |
| Delta-24 increases the expression and activity of topoisomerase I and enhances the antiglioma effect of irinotecan. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060115 |
| Novel toll-like receptor 9 agonist induces epidermal growth factor receptor (EGFR) inhibition and synergistic antitumor activity with EGFR inhibitors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060115 |
| Cetuximab and irinotecan interact synergistically to inhibit the growth of orthotopic anaplastic thyroid carcinoma xenografts in nude mice. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060115 |
| Equivalent effect of DNA damage-induced apoptotic cell death or long-term cell cycle arrest on colon carcinoma cell proliferation and tumour growth. | Oncogene 20060112 |
| A phase I study of irinotecan administered on a weekly schedule in pediatric patients. | Pediatric blood & cancer 20060101 |
| Phase I study of the combination of topotecan and irinotecan in children with refractory solid tumors. | Cancer chemotherapy and pharmacology 20060101 |
| Characterization of secretory intestinal transport of the lactone form of CPT-11. | Cancer chemotherapy and pharmacology 20060101 |
| Sequential administration of irinotecan and cytarabine in the treatment of relapsed and refractory acute myeloid leukemia. | Cancer chemotherapy and pharmacology 20060101 |
| Phase II study of tailored chemotherapy for advanced colorectal cancer with either 5-fluouracil and leucovorin or oxaliplatin and irinotecan based on the expression of thymidylate synthase and dihydropyrimidine dehydrogenase. | Annals of oncology : official journal of the European Society for Medical Oncology 20060101 |
| Activity of irinotecan and the tyrosine kinase inhibitor CEP-751 in medullary thyroid cancer. | The Journal of clinical endocrinology and metabolism 20060101 |
| Comparative genomics analysis of human sequence variation in the UGT1A gene cluster. | The pharmacogenomics journal 20060101 |
| Irinotecan (CPT-11) combined with bolus 5-fluorouracil/leucovorin (Saltz regimen) as first-line chemotherapy of patients with advanced colorectal cancer. | Anti-cancer drugs 20060101 |
| Gemcitabine-related radiation recall in a patient with pancreatic cancer. | Anti-cancer drugs 20060101 |
| A National Cancer Institute of Canada Clinical Trials Group Study--IND.135: Phase I/II study of irinotecan (camptosar), oxaliplatin and raltitrexed (tomudex) (COT) in patients with advanced colorectal cancer. | European journal of cancer (Oxford, England : 1990) 20060101 |
| What is the best sequence of chemotherapy in advanced colorectal cancer? Final results of a five-arm study. | Chemotherapy 20060101 |
| Second- and third-line treatments in non-small cell lung cancer. | Current treatment options in oncology 20060101 |
| Management of small cell lung cancer. | Current treatment options in oncology 20060101 |
| Novel two-step resection for lesions between the middle hepatic vein and vena cava which allows the middle hepatic vein to be preserved. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20060101 |
| Rubitecan. | Expert opinion on investigational drugs 20060101 |
| Unresectable hepatic colorectal metastases: need for new surgical strategies. | Annals of surgical oncology 20060101 |
| Treatment with 5-fluorouracil/folinic acid, oxaliplatin, and irinotecan enables surgical resection of metastases in patients with initially unresectable metastatic colorectal cancer. | Annals of surgical oncology 20060101 |
| Intraperitoneal versus intravenous CPT-11 given intra- and postoperatively for peritoneal carcinomatosis in a rat model. | Surgery today 20060101 |
| Adjuvant therapy for colon cancer 2005: new options in the twenty-first century. | Surgical oncology clinics of North America 20060101 |
| [Comparison of dexamethasone 8 mg and 16 mg for the prevention of acute and delayed cisplatin-induced emesis in patients with lung cancer]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20060101 |
| Adding pharmacogenomics to the development of new marine-derived anticancer agents. | Journal of translational medicine 20060101 |
| Gefitinib response of erlotinib-refractory lung cancer involving meninges--role of EGFR mutation. | Nature clinical practice. Oncology 20060101 |
| Novel three-pronged strategy to enhance cancer cell killing in glioblastoma cell lines: histone deacetylase inhibitor, chemotherapy, and oncolytic adenovirus dl520. | Human gene therapy 20060101 |
| [Management of chemotherapy-induced mucositis and diarrhea]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060101 |
| [A case report of poorly-differentiated adenocarcinoma in sigmoid colon cancer with liver and pulmonary metastasis responding to TS-1 and CPT-11]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060101 |
| A case of bone metastasis of colon cancer that markedly responded to S-1/CPT-11 combination chemotherapy and became curable by resection. | World journal of surgical oncology 20060101 |
| Enhancement of DNA topoisomerase I inhibitor-induced apoptosis by ursodeoxycholic acid. | Molecular cancer therapeutics 20060101 |
| Cetuximab preclinical antitumor activity (monotherapy and combination based) is not predicted by relative total or activated epidermal growth factor receptor tumor expression levels. | Molecular cancer therapeutics 20060101 |
| Neutropenic colitis during standard dose combination chemotherapy with nedaplatin and irinotecan for testicular cancer. | Japanese journal of clinical oncology 20060101 |
| Transport mechanism-based drug molecular design: novel camptothecin analogues to circumvent ABCG2-associated drug resistance of human tumor cells. | Current pharmaceutical design 20060101 |
| [Irinotecan chemotherapy for patients with advanced or relapsed pancreatic neoplasm]. | Nihon rinsho. Japanese journal of clinical medicine 20060101 |
| Prognostic significance of pathological response after neoadjuvant chemotherapy or chemoradiation for locally advanced cervical carcinoma. | International seminars in surgical oncology : ISSO 20060101 |
| An integrated psychological strategy for advanced colorectal cancer patients. | Health and quality of life outcomes 20060101 |
| Influence of irinotecan and SN-38 on the irradiation response of WHO3 human oesophageal tumour cells under hypoxic conditions. | Anticancer research 20060101 |
| Circumvention of camptothecin-induced resistance during the adaptive cellular stress response. | Anticancer research 20060101 |
| [A case of small cell carcinoma of the lung associated with paraneoplastic cerebellar degeneration and Lambert-Eaton myasthenic syndrome]. | No to shinkei = Brain and nerve 20060101 |
| Small cell lung cancer: an update on therapeutic aspects. | The Indian journal of chest diseases & allied sciences 20060101 |
| Phase I study of intermittent and chronomodulated oral therapy with capecitabine in patients with advanced and/or metastatic cancer. | BMC cancer 20060101 |
| Prognostic significance of HER3 and HER4 protein expression in colorectal adenocarcinomas. | BMC cancer 20060101 |
| Genetic polymorphisms of drug-metabolising enzymes and drug transporters in the chemotherapeutic treatment of cancer. | Clinical pharmacokinetics 20060101 |
| Disruption of nucleocytoplasmic trafficking of cyclin D1 and topoisomerase II by sanguinarine. | BMC cell biology 20060101 |
| Metastatic ovarian carcinoma one year after surgical removal of colon carcinoma during pregnancy: a case report. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101 |
| Chylous ascites following operation for para-aortic lymph node dissection in a patient with cervical cancer. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101 |
| Phospholipid fatty acid composition and diamine oxidase activity of intestinal mucosa from rats treated with irinotecan hydrochloride (CPT-11) under vegetable oil-enriched diets: comparison between perilla oil and corn oil. | JPEN. Journal of parenteral and enteral nutrition 20060101 |
| Camptothecin and podophyllotoxin derivatives: inhibitors of topoisomerase I and II - mechanisms of action, pharmacokinetics and toxicity profile. | Drug safety 20060101 |
| Characterization of a CC49-based single-chain fragment-beta-lactamase fusion protein for antibody-directed enzyme prodrug therapy (ADEPT). | Bioconjugate chemistry 20060101 |
| Deciphering cellular states of innate tumor drug responses. | Genome biology 20060101 |
| [Myelotoxity of the nuclear enzyme inhibitors irinotecan and etoposide]. | Eksperimental'naia i klinicheskaia farmakologiia 20060101 |
| Irinotecan as a new agent for urachal cancer. | Urologia internationalis 20060101 |
| Perioperative intraperitoneal chemotherapy for peritoneal surface malignancy. | Journal of translational medicine 20060101 |
| Second-line combination chemotherapy of oral S-1 with cisplatin and irinotecan for colorectal cancer resistant to 5-FU. | Hepato-gastroenterology 20060101 |
| A phase I trial of CPT-11 in combination with 5-fluorouracil plus leucovorin chemotherapy for patients with metastatic colorectal cancer. | Hepato-gastroenterology 20060101 |
| Combination effect of TZT-1027 (Soblidotin) with other anticancer drugs. | Anticancer research 20060101 |
| In vivo disposition of irinotecan (CPT-11) and its metabolites in combination with the monoclonal antibody cetuximab. | Anticancer research 20060101 |
| Potential predictors of long-term survival after surgery for patients with stage IV colorectal cancer. | Anticancer research 20060101 |
| Feasibility study of biweekly CPT-11 plus CDDP for S-1- and paclitaxel-refractory, metastatic gastric cancer. | Anticancer research 20060101 |
| Salvage treatment with single-agent capecitabine in patients with heavily pretreated advanced colorectal cancer. | Anticancer research 20060101 |
| The challenge for genetic epidemiologists: how to analyze large numbers of SNPs in relation to complex diseases. | BMC genetics 20060101 |
| Multicenter phase II study of gemcitabine and oxaliplatin (GEMOX) as second-line chemotherapy in colorectal cancer patients pretreated with 5-fluorouracil plus irinotecan. | Oncology 20060101 |
| A phase II study of irinotecan with 5-fluorouracil and leucovorin in patients with pretreated gastroenteropancreatic well-differentiated endocrine carcinomas. | Oncology 20060101 |
| A phase II study of LFP therapy (5-FU (5-fluorourasil) continuous infusion (CVI) and Low-dose consecutive (Cisplatin) CDDP) in advanced biliary tract carcinoma. | BMC cancer 20060101 |
| Cancer and kinases: reports from the front line. | Genome biology 20060101 |
| Neoadjuvant chemotherapy in cervical cancer: a 67 patients experience. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101 |
| Treatment of non-small cell lung cancer with intensity-modulated radiation therapy in combination with cetuximab: the NEAR protocol (NCT00115518). | BMC cancer 20060101 |
| HER 2/neu protein expression in colorectal cancer. | BMC cancer 20060101 |
| A 96-well efflux assay to identify ABCG2 substrates using a stably transfected MDCK II cell line. | Molecular pharmaceutics 20060101 |
| Downregulation of survivin expression and concomitant induction of apoptosis by celecoxib and its non-cyclooxygenase-2-inhibitory analog, dimethyl-celecoxib (DMC), in tumor cells in vitro and in vivo. | Molecular cancer 20060101 |
| Cellular response to 5-fluorouracil (5-FU) in 5-FU-resistant colon cancer cell lines during treatment and recovery. | Molecular cancer 20060101 |
| Radiosensitizers in cervical cancer. Cisplatin and beyond. | Radiation oncology (London, England) 20060101 |
| Spotlight on bevacizumab in advanced colorectal cancer, breast cancer, and non-small cell lung cancer. | BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20060101 |
| About the cover: St. John's wort. | Journal of the Society for Integrative Oncology 20060101 |
| Stable disease in advanced colorectal cancer: therapeutic implications. | Anticancer research 20060101 |
| Both bronchial and vascular stenting followed by chemoradiotherapy for locally advanced non-small cell lung cancer. | Anticancer research 20060101 |
| Single-agent irinotecan for recurrent/metastatic colorectal cancer: a retrospective analysis. | Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20060101 |
| A Phase II NCCTG study of irinotecan and docetaxel in previously treated patients with non-small cell lung cancer. | Cancer investigation 20060101 |
| Mechanism of central nervous system toxicity by irinotecan. | Medical hypotheses 20060101 |
| Survival of patients with colorectal cancer liver metastases treated by regional chemotherapy. | Hepato-gastroenterology 20060101 |
| Evaluation of gefitinib for treatment of refractory solid tumors and central nervous system malignancies in pediatric patients. | Cancer investigation 20060101 |
| Glucuronidation of SN-38 and NU/ICRF 505 in human colon cancer and adjacent normal colon. | Anticancer research 20060101 |
| A phase I study of irinotecan in combination with amrubicin for advanced lung cancer patients. | Anticancer research 20060101 |
| Proteasome inhibition with bortezomib enhances activity of topoisomerase I-targeting drugs by NF-kappaB-independent mechanisms. | Anticancer research 20060101 |
| Review camptothecin: current perspectives. | Current medicinal chemistry 20060101 |
| Gemcitabine in combination with EGF-Receptor antibody (Cetuximab) as a treatment of cholangiocarcinoma: a case report. | BMC cancer 20060101 |
| Irinotecan combined with infusional 5-fluorouracil and high-dose leucovorin for the treatment of advanced gastric carcinoma as the first-line chemotherapy. | Chemotherapy 20060101 |
| Pharmacogenetics of uridine diphosphoglucuronosyltransferase (UGT) 1A family members and its role in patient response to irinotecan. | Drug metabolism reviews 20060101 |
| [Pharmacogenetics and pharmacogenomics]. | Bulletin de l'Academie nationale de medecine 20060101 |
| Topical treatment with oxaliplatin for the prevention of port-site metastases in laparoscopic surgery for colorectal cancer. | JSLS : Journal of the Society of Laparoendoscopic Surgeons 20060101 |
| PARP-1 inhibitors: are they the long-sought genetically specific drugs for BRCA1/2-associated breast cancers? | International journal of medical sciences 20060101 |
| Decreasing dosage of irinotecan, 5-flurouracil (5-FU) and leucovorin (LV) in the treatment of advanced and/or metastatic colorectal cancer: a phase II study. | Chang Gung medical journal 20060101 |
| Combination chemotherapy with irinotecan and cisplatin in pretreated patients with unresectable or recurrent gastric cancer. | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20060101 |
| A case report and discussion of cetuximab-induced folliculitis. | American journal of clinical dermatology 20060101 |
| Combined chemotherapy of irinotecan and low-dose cisplatin (I/low-P) against metastatic biliary tract cancer. | Journal of hepato-biliary-pancreatic surgery 20060101 |
| Clinical predictors of severe toxicity in patients treated with combination chemotherapy with irinotecan and/or oxaliplatin for metastatic colorectal cancer: a single center experience. | Medical oncology (Northwood, London, England) 20060101 |
| Clinicopathological significance of stromal variables: angiogenesis, lymphangiogenesis, inflammatory infiltration, MMP and PINCH in colorectal carcinomas. | Molecular cancer 20060101 |
| Chemotherapy with mitomycin C and capecitabine in patients with advanced colorectal cancer pretreated with irinotecan and oxaliplatin. | Tumori 20060101 |
| Single-agent irinotecan as second-line weekly chemotherapy in elderly patients with advanced colorectal cancer. | Tumori 20060101 |
| In vitro thermochemotherapy of colon cancer cell lines with irinotecan alone and combined with mitomycin C. | Hepato-gastroenterology 20060101 |
| Modeling biological rhythms in failure time data. | Journal of circadian rhythms 20060101 |
| Trans-arterial chemoembolization (TACE) of liver metastases from colorectal cancer using irinotecan-eluting beads: preliminary results. | Anticancer research 20060101 |
| Recent progress in target therapy in colorectal cancer. | Anticancer research 20060101 |
| New molecular mechanisms of action of camptothecin-type drugs. | Anticancer research 20060101 |
| Panitumumab: in the treatment of metastatic colorectal cancer. | Drugs 20060101 |
| Radiation-sparing managements for cervical cancer: a developing countries perspective. | World journal of surgical oncology 20060101 |
| Chronomodulated irinotecan, oxaliplatin, and leucovorin-modulated 5-Fluorouracil as ambulatory salvage therapy in patients with irinotecan- and oxaliplatin-resistant metastatic colorectal cancer. | The oncologist 20060101 |
| Preliminary results of phase I trial of oral uracil/tegafur (UFT), leucovorin plus irinotecan and radiation therapy for patients with locally recurrent rectal cancer. | World journal of surgical oncology 20060101 |
| Complete response of highly advanced colon cancer with multiple lymph node metastases to irinotecan combined with UFT: report of a case. | Surgery today 20060101 |
| Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma. | Molecular cancer 20060101 |
| Pharmacogenomics and colorectal cancer. | Advances in experimental medicine and biology 20060101 |
| Is EGFR expression altered following postoperative chemotherapy for colorectal adenocarcinoma? | World journal of surgical oncology 20060101 |
| Irinotecan, fluorouracil and folinic acid (FOLFIRI) as effective treatment combination for patients with advanced gastric cancer in poor clinical condition. | Tumori 20060101 |
| Multiple-target chemotherapy (LV-modulated 5-FU bolus and continuous infusion, oxaliplatin, CPT- 11) in advanced 5-FU-refractory colorectal cancer: MTD definition and efficacy evaluation. A phase I-II study. | Tumori 20060101 |
| Drug-herb interactions: eliminating toxicity with hard drug design. | Current pharmaceutical design 20060101 |
| Development of a tumor-selective approach to treat metastatic cancer. | PloS one 20060101 |
| Financial considerations in the conduct of multi-centre randomised controlled trials: evidence from a qualitative study. | Trials 20060101 |
| Apigenin inhibits pancreatic cancer cell proliferation through G2/M cell cycle arrest. | Molecular cancer 20060101 |
| Expression of genes for 5-FU-metabolizing enzymes and response to irinotecan plus 5-FU-leucovorin in colorectal cancer. | Anticancer research 20060101 |
| Post-operative combined radiation and chemotherapy with temozolomide and irinotecan in patients with high-grade astrocytic tumors. A phase II study with biomarker evaluation. | Anticancer research 20060101 |
| Weekly administration of irinotecan (CPT-11) plus cisplatin for non-small cell lung cancer. | Anticancer research 20060101 |
| Hepatic metastases of colorectal cancer: locoregional intra-arterial treatment. | Anticancer research 20060101 |
| [Chemotherapy agents, response rates and mechanisms of resistance in the therapy of the colorectal carcinoma]. | Magyar onkologia 20060101 |
| Genome-wide cDNA microarray screening of genes related to the benefits of paclitaxel and irinotecan chemotherapy in patients with advanced non-small cell lung cancer. | Journal of experimental therapeutics & oncology 20060101 |
| [Metastatic colorectal cancer: adjournments from ESMO 2006]. | Tumori 20060101 |
| [A review of chemotherapy for metastatic colon cancer]. | Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20060101 |
| Novel approaches to treatment of advanced colorectal cancer with anti-EGFR monoclonal antibodies. | Annals of medicine 20060101 |
| Resection of small bowel adenocarcinoma liver metastasis combined with neoadjuvant and adjuvant chemotherapy results in extended disease-free period--a case report. | International journal of gastrointestinal cancer 20060101 |
| Feasibility of sequential therapy with FOLFIRI followed by docetaxel/cisplatin in patients with radically resected gastric adenocarcinoma. A randomized phase III trial. | Oncology 20060101 |
| Colorectal cancer: from epidemiology to current treatment. | The Libyan journal of medicine 20060101 |
| Conformal radiotherapy and molecular imaging: complementary technologies in cancer therapy. | Biomedical imaging and intervention journal 20060101 |
| Trans-arterial hepatic radioembolisation of yttrium-90 microspheres. | Biomedical imaging and intervention journal 20060101 |
| Overall survival of patients with advanced colorectal cancer correlates with availability of fluorouracil, irinotecan, and oxaliplatin regardless of whether doublet or single-agent therapy is used first line. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051220 |
| Esters and amides of 2,3-dimethoxy-8,9-methylenedioxy-benzo[i]phenanthridine-12-carboxylic acid: potent cytotoxic and topoisomerase I-targeting agents. | Bioorganic & medicinal chemistry 20051215 |
| Inhibition of acetylcholinesterase by the anticancer prodrug CPT-11. | Chemico-biological interactions 20051215 |
| The 3D structure of the anticancer prodrug CPT-11 with Torpedo californica acetylcholinesterase rationalizes its inhibitory action on AChE and its hydrolysis by butyrylcholinesterase and carboxylesterase. | Chemico-biological interactions 20051215 |
| Phase II study of weekly irinotecan plus capecitabine for chemotherapy-naive patients with advanced nonsmall cell lung carcinoma. | Cancer 20051215 |
| A phase I/II trial of irinotecan-cisplatin combined with an anti-late-diarrhoeal programme to evaluate the safety and antitumour response of this combination therapy in patients with advanced non-small-cell lung cancer. | British journal of cancer 20051212 |
| [Colorectal carcinoma in elderly patients]. | Praxis 20051207 |
| Activation and antitumor activity of CPT-11 in plasma esterase-deficient mice. | Cancer chemotherapy and pharmacology 20051201 |
| A phase I trial of celecoxib in combination with docetaxel and irinotecan in patients with advanced cancer. | Cancer chemotherapy and pharmacology 20051201 |
| Conventional surgery and systemic chemotherapy for peritoneal carcinomatosis of colorectal origin: a prospective study. | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20051201 |
| Gefitinib (Iressa) inhibits the CYP3A4-mediated formation of 7-ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin but activates that of 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino]carbonyloxycamptothecin from irinotecan. | Drug metabolism and disposition: the biological fate of chemicals 20051201 |
| [Which role do new therapeutic options play in palliative care of colorectal cancer?]. | Der Internist 20051201 |
| Evaluation of irinotecan plus paclitaxel in patients with advanced non-small cell lung cancer. | Cancer biology & therapy 20051201 |
| Pharmacogenetics of irinotecan: a promoter polymorphism of UGT1A1 gene and severe adverse reactions to irinotecan. | Investigational new drugs 20051201 |
| Clinical usefulness of oral granisetron hydrochloride for alleviation of delayed nausea and vomiting induced by CPT-11. | European journal of cancer care 20051201 |
| Pharmacokinetic modelling of 5-FU production from capecitabine--a population study in 40 adult patients with metastatic cancer. | Journal of pharmacokinetics and pharmacodynamics 20051201 |
| Biological markers as a predictor for response and prognosis of unresectable gastric cancer patients treated with irinotecan and cisplatin. | Japanese journal of clinical oncology 20051201 |
| Pharmacogenetics of colorectal cancer. | Expert opinion on pharmacotherapy 20051201 |
| A multicenter phase II study of 'adjuvant' irinotecan following resection of colorectal hepatic metastases. | American journal of clinical oncology 20051201 |
| Efficacy and tolerability of oxaliplatin plus irinotecan 5-fluouracil and leucovorin regimen in advanced stage colorectal cancer patients pretreated with irinotecan 5-fluouracil and leucovorin. | American journal of clinical oncology 20051201 |
| Irinotecan (CPT-11) and mitomycin-C (MMC) as second-line therapy in advanced gastric cancer: a phase II study of the Gruppo Oncologico dell' Italia Meridionale (prot. 2106). | American journal of clinical oncology 20051201 |
| [Progression of adjuvant chemotherapy for colon cancer]. | Ai zheng = Aizheng = Chinese journal of cancer 20051201 |
| [Recent progress of chemotherapy for colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20051201 |
| [CPT-11-induced diarrhea treated with indisetron hydrochloride--a case report]. | Gan to kagaku ryoho. Cancer & chemotherapy 20051201 |
| Metastatic colorectal cancer: first- and second-line treatment in 2005. | Seminars in oncology 20051201 |
| Biweekly irinotecan and cisplatin as second-line chemotherapy in pretreated patients with advanced gastric cancer: a multicenter phase II study. | Journal of Korean medical science 20051201 |
| Antivascular therapy of oral tongue squamous cell carcinoma with PTK787. | The Laryngoscope 20051201 |
| Phase I study of cisplatin and irinotecan combined with concurrent hyperfractionated accelerated thoracic radiotherapy for locally advanced non-small cell lung carcinoma. | International journal of clinical oncology 20051201 |
| Small cell carcinoma of the esophagus responding to fourth-line chemotherapy with weekly paclitaxel. | International journal of clinical oncology 20051201 |
| Intravenous irinotecan plus oral ciclosporin. | Clinical oncology (Royal College of Radiologists (Great Britain)) 20051201 |
| Irinotecan with bolus and infusional 5-flurouracil and folinic acid for patients with advanced or metastatic colorectal cancer previously treated with 5-flurouracil: a possible alternative to single-agent irinotecan in a 'real-life' setting. | Clinical oncology (Royal College of Radiologists (Great Britain)) 20051201 |
| Sensitization of DNA damage-induced apoptosis by the proteasome inhibitor PS-341 is p53 dependent and involves target proteins 14-3-3sigma and survivin. | Molecular cancer therapeutics 20051201 |
| Chemotherapy and TRAIL-mediated colon cancer cell death: the roles of p53, TRAIL receptors, and c-FLIP. | Molecular cancer therapeutics 20051201 |
| First-line chemotherapy for advanced-stage non-small-cell lung cancer: focus on docetaxel. | Clinical lung cancer 20051201 |
| Multimodality therapy of local regional esophageal cancer. | Seminars in oncology 20051201 |
| Front-line therapy for advanced colorectal cancer: emphasis on chemotherapy. | Seminars in oncology 20051201 |
| The role of bevacizumab as first-line therapy for colon cancer. | Seminars in oncology 20051201 |
| Second-line treatment of patients with metastatic colorectal cancer. | Seminars in oncology 20051201 |
| The role of cetuximab in the therapy of previously treated advanced colorectal cancer. | Seminars in oncology 20051201 |
| Correlation between the response to cetuximab alone or in combination with irinotecan and the activated/phosphorylated epidermal growth factor receptor in metastatic colorectal cancer. | Seminars in oncology 20051201 |
| Adjuvant chemotherapy of stage III colon cancer. | Seminars in oncology 20051201 |
| Neoadjuvant chemotherapy, surgery, and adjuvant intraperitoneal chemotherapy in patients with locally advanced gastric or gastroesophageal junction carcinoma: a phase II study. | Seminars in oncology 20051201 |
| Cetuximab: new drug. Metastatic colorectal cancer: an inappropriate evaluation. | Prescrire international 20051201 |
| Chemotherapy of metastatic colorectal cancer: fluorouracil plus folinic acid and irinotecan or oxaliplatin. | Prescrire international 20051201 |
| A phase II trial of irinotecan in patients with previously untreated advanced esophageal and gastric adenocarcinoma. | Digestive diseases and sciences 20051201 |
| The emerging role of oxaliplatin in the treatment of gastric cancer. | Journal of chemotherapy (Florence, Italy) 20051201 |
| A slow disengagement from platinum-based chemotherapy for patients with advanced non-small cell lung cancer. | Cancer biology & therapy 20051201 |
| A case of esophageal small cell carcinoma with multiple liver metastases responding to chemotherapy with irinotecan plus cisplatin. | Journal of experimental & clinical cancer research : CR 20051201 |
| Optimizing chemotherapy for advanced non-small cell lung cancer: focus on docetaxel. | Lung cancer (Amsterdam, Netherlands) 20051201 |
| Management of oxaliplatin-induced peripheral neuropathy. | Therapeutics and clinical risk management 20051201 |
| Liposomalization of SN-38 as active metabolite of CPT-11. | Journal of controlled release : official journal of the Controlled Release Society 20051128 |
| Phase II randomised trial of raltitrexed-oxaliplatin vs raltitrexed-irinotecan as first-line treatment in advanced colorectal cancer. | British journal of cancer 20051128 |
| A meta-analysis of two randomised trials of early chemotherapy in asymptomatic metastatic colorectal cancer. | British journal of cancer 20051128 |
| The radical scavenger edaravone enhances the anti-tumor effects of CPT-11 in murine colon cancer by increasing apoptosis via inhibition of NF-kappaB. | Cancer letters 20051118 |
| Potential hazard of pharmacokinetic interactions between lopinavir-ritonavir protease inhibitors and irinotecan. | AIDS (London, England) 20051118 |
| Phase II study of concurrent chemoradiotherapy with capecitabine and cisplatin in patients with locally advanced squamous cell carcinoma of the head and neck. | British journal of cancer 20051114 |
| Front-line paclitaxel and irinotecan combination chemotherapy in advanced non-small-cell lung cancer: a phase I-II trial. | British journal of cancer 20051114 |
| Phase II study of gemcitabine and cisplatin in locally advanced/metastatic oesophageal cancer. | British journal of cancer 20051114 |
| [Drug therapy of patients with metastatic colorectal cancer]. | Ugeskrift for laeger 20051107 |
| Evidence of activity of Irinotecan in patients with advanced AIDS-related Kaposi's sarcoma. | AIDS (London, England) 20051104 |
| National differences in reporting 'pneumonia' and 'pneumonia interstitial': an analysis of the WHO International Drug Monitoring Database on 15 drugs in nine countries for seven pulmonary conditions. | Pharmacoepidemiology and drug safety 20051101 |
| Irinotecan combined with docetaxel in pre-treated metastatic breast cancer patients: a phase II study. | Cancer chemotherapy and pharmacology 20051101 |
| Spectrophotometric investigation of the chemical compatibility of the anticancer drugs irinotecan-HCl and epirubicin-HCl in the same infusion solution. | Cancer chemotherapy and pharmacology 20051101 |
| S-phase modulation by irinotecan: pilot studies in advanced solid tumors. | Cancer chemotherapy and pharmacology 20051101 |
| Phase I study of etoposide, cisplatin and irinotecan triplet in patients with advanced-stage small-cell lung cancer. | Cancer chemotherapy and pharmacology 20051101 |
| Chemotherapy for colorectal cancer--an overview of current management for surgeons. | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20051101 |
| Plant-based anticancer molecules: a chemical and biological profile of some important leads. | Bioorganic & medicinal chemistry 20051101 |
| Combination chemotherapy with gemcitabine and irinotecan in patients with previously treated carcinoma of an unknown primary site: a Minnie Pearl Cancer Research Network Phase II trial. | Cancer 20051101 |
| Human multidrug resistance associated protein 4 confers resistance to camptothecins. | Pharmaceutical research 20051101 |
| Cost-effectiveness projections of oxaliplatin and infusional fluorouracil versus irinotecan and bolus fluorouracil in first-line therapy for metastatic colorectal carcinoma. | Cancer 20051101 |
| Combination effects of irradiation and irinotecan on cervical squamous cell carcinoma cells in vitro. | Oncology reports 20051101 |
| Chemotherapy and radiotherapy in the management of gastric cancer. | Current opinion in gastroenterology 20051101 |
| The epidermal growth factor receptor tyrosine kinase inhibitor gefitinib sensitizes colon cancer cells to irinotecan. | Anti-cancer drugs 20051101 |
| Irinotecan (CPT-11) in the treatment of mycosis fungoides. | The British journal of dermatology 20051101 |
| Drug Insight: Metastatic colorectal cancer--oral fluoropyrimidines and new perspectives in the adjuvant setting. | Nature clinical practice. Oncology 20051101 |
| Effect of milk thistle (Silybum marianum) on the pharmacokinetics of irinotecan. | Clinical cancer research : an official journal of the American Association for Cancer Research 20051101 |
| [SNPs associated with adverse effects]. | Gan to kagaku ryoho. Cancer & chemotherapy 20051101 |
| [A case of cecal cancer with multiple liver metastases responding to irinotecan (CPT-11)/cisplatin (CDDP) combination therapy for elevation of CA19-9 after complete response (CR) by l-leucovorin(LV)/5-fluorouracil(5-FU) therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20051101 |
| [A case of rectal cancer treated by preoperative chemoradiation]. | Gan to kagaku ryoho. Cancer & chemotherapy 20051101 |
| Successful treatment of chemoresistant stage 3 neuroblastoma using irinotecan as a single agent. | Journal of pediatric hematology/oncology 20051101 |
| [A case of metastasis-induced acute pancreatitis improved by chemotherapy]. | The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20051101 |
| Recent data with anti-epidermal growth factor receptor antibodies and irinotecan in colon cancer. | Clinical colorectal cancer 20051101 |
| Enhancing oxaliplatin-based regimens in colorectal cancer by inhibiting the epidermal growth factor receptor pathway. | Clinical colorectal cancer 20051101 |
| Phase I/II dose-escalation study of pemetrexed plus irinotecan in patients with advanced colorectal cancer. | Clinical colorectal cancer 20051101 |
| FOLFOX alternated with FOLFIRI as first-line chemotherapy for metastatic colorectal cancer. | Clinical colorectal cancer 20051101 |
| Outcomes in elderly patients with advanced colorectal cancer treated with capecitabine: a population-based analysis. | Clinical colorectal cancer 20051101 |
| UGT1A1 genotyping in patients undergoing treatment with irinotecan. | Clinical advances in hematology & oncology : H&O 20051101 |
| Cytotoxic chemotherapy for advanced colorectal cancer. Recent advances in management. | Oncology (Williston Park, N.Y.) 20051101 |
| Longitudinal quality of life study in patients with metastatic gastric cancer. Analysis modalities and clinical applicability of QoL in randomized phase II trial in a digestive oncology. | Gastroenterologie clinique et biologique 20051101 |
| Prospective validation of quantitative CEA mRNA detection in peritoneal washes in gastric carcinoma patients. | British journal of cancer 20051031 |
| A phase I/II study of oxaliplatin when added to 5-fluorouracil and leucovorin and pelvic radiation in locally advanced rectal cancer: a Colorectal Clinical Oncology Group (CCOG) study. | British journal of cancer 20051031 |
| A phase I pharmacokinetic and pharmacodynamic study of BGC9331 and carboplatin in relapsed gynaecological malignancies. | British journal of cancer 20051017 |
| Modulation of 5-fluorouracil as adjuvant systemic chemotherapy in colorectal cancer: the IGCS-COL multicentre, randomised, phase III study. | British journal of cancer 20051017 |
| The novel lipophilic camptothecin analogue gimatecan is very active in vitro in human neuroblastoma: a comparative study with SN38 and topotecan. | Biochemical pharmacology 20051015 |
| Second-line treatment with irinotecan plus cisplatin vs cisplatin of patients with advanced non-small-cell lung cancer pretreated with taxanes and gemcitabine: a multicenter randomised phase II study. | British journal of cancer 20051003 |
| Modulation of irinotecan with cyclosporine: a phase II trial in advanced colorectal cancer. | Cancer chemotherapy and pharmacology 20051001 |
| Front-line treatment of advanced non-small cell lung cancer with irinotecan and docetaxel: a multicentre phase II study. | Lung cancer (Amsterdam, Netherlands) 20051001 |
| Functional characterization of three naturally occurring single nucleotide polymorphisms in the CES2 gene encoding carboxylesterase 2 (HCE-2). | Drug metabolism and disposition: the biological fate of chemicals 20051001 |
| Phase I trial of irinotecan plus temozolomide in adults with recurrent malignant glioma. | Cancer 20051001 |
| MRP1 mutated in the L0 region transports SN-38 but not leukotriene C4 or estradiol-17 (beta-D-glucuronate). | Biochemical pharmacology 20051001 |
| Genetic determinants of cancer drug efficacy and toxicity: practical considerations and perspectives. | Anti-cancer drugs 20051001 |
| Systemic therapy for pancreatic cancer. | Seminars in radiation oncology 20051001 |
| Modulation of cytochrome P450 activity: implications for cancer therapy. | The Lancet. Oncology 20051001 |
| A phase I/II study of trimetrexate and capecitabine in patients with advanced refractory colorectal cancer. | American journal of clinical oncology 20051001 |
| Carboxylesterase isoform 2 mRNA expression in peripheral blood mononuclear cells is a predictive marker of the irinotecan to SN38 activation step in colorectal cancer patients. | Clinical cancer research : an official journal of the American Association for Cancer Research 20051001 |
| Effect of p53 status and STAT1 on chemotherapy-induced, Fas-mediated apoptosis in colorectal cancer. | Cancer research 20051001 |
| Reduced dose intensity FOLFOX-4 as first line palliative chemotherapy in elderly patients with advanced colorectal cancer. | Journal of Korean medical science 20051001 |
| [A case of advanced gastric cancer with obstructive jaundice that responded to TS-1/CPT-11 combination therapy after percutaneous transhepatic cholangio drainage]. | Gan to kagaku ryoho. Cancer & chemotherapy 20051001 |
| [A case of small cell carcinoma of the stomach]. | Gan to kagaku ryoho. Cancer & chemotherapy 20051001 |
| [A case of colon cancer with multiple liver, lung and bone metastases successfully treated with combined weekly high-dose 5-FU (WHF) chemotherapy with UFT and CPT-11]. | Gan to kagaku ryoho. Cancer & chemotherapy 20051001 |
| Advanced colorectal cancer: current treatment and nursing management with economic considerations. | Clinical journal of oncology nursing 20051001 |
| [Surgical treatment for locally advanced lung cancer; therapeutic response of induction chemotherapy and postoperative chemotherapy]. | Kyobu geka. The Japanese journal of thoracic surgery 20051001 |
| In vitro detection of cross-resistant and non-cross-resistant agents with fluorouracil for patients with colorectal cancer. | International journal of clinical oncology 20051001 |
| Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity. | Current drug metabolism 20051001 |
| Topotecan: weighing in when there are many options. | The oncologist 20051001 |
| Combined therapy with weekly irinotecan, infusional 5-fluorouracil and the selective COX-2 inhibitor rofecoxib is a safe and effective second-line treatment in metastatic colorectal cancer. | The oncologist 20051001 |
| Drug Discovery Technology and Development 2005 - IBC's Tenth World Congress. Cancer mouse models and other techniques for improved prediction of efficacy. | IDrugs : the investigational drugs journal 20051001 |
| Rapid evolution in colorectal cancer: therapy now and over the next five years. | The oncologist 20051001 |
| [Host immunity in colorectal cancer patients treated with TS-1 plus CPT-11]. | Gan to kagaku ryoho. Cancer & chemotherapy 20051001 |
| [Chemotherapy for patients with advanced/recurrent gastric cancer and the practice at our institute]. | Gan to kagaku ryoho. Cancer & chemotherapy 20051001 |
| [Chemotherapy for liver metastasis of colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20051001 |
| [A case of peritoneal dissemination disappeared by CPT-11 + TS-1 combination chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20051001 |
| [A case of an increase in resectability with preoperative chemotherapy TS-1 combined with CPT-11 for unresectable rectal cancer in downstaging]. | Gan to kagaku ryoho. Cancer & chemotherapy 20051001 |
| [A case of metastatic colon cancer treated with oxaliplatin combination chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20051001 |
| [A case of chemoradiation with tissue expander for local reccurence of rectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20051001 |
| [Two cases of postoperative local skin recurrence of breast cancer successfully treated with chemotherapy of irinotecan hydrochloride (CPT-11)]. | Gan to kagaku ryoho. Cancer & chemotherapy 20051001 |
| [A case report of recurrence of liver metastases from colorectal cancer, which seemed to have vanished for a time by intra-aortic chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20051001 |
| Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism. | Bioorganic & medicinal chemistry letters 20050915 |
| Fluorescence detection combined with either HPLC or HPTLC for pharmaceutical quality control in a hospital chemotherapy production unit: application to camptothecin derivatives. | Journal of pharmaceutical and biomedical analysis 20050915 |
| A phase I study and pharmacologic evaluation of irinotecan and carboplatin for patients with advanced ovarian carcinoma who previously received platinum-containing chemotherapy. | Cancer 20050915 |
| Molecular alterations in tumors and response to combination chemotherapy with gefitinib for advanced colorectal cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050915 |
| Effects of ketoconazole on glucuronidation by UDP-glucuronosyltransferase enzymes. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050915 |
| Regulation of hepatocyte engraftment and proliferation after cytotoxic drug-induced perturbation of the rat liver. | Transplantation 20050915 |
| Dendritic supramolecular assemblies for drug delivery. | Chemical communications (Cambridge, England) 20050914 |
| Capecitabine and mitomycin C as third-line therapy for patients with metastatic colorectal cancer resistant to fluorouracil and irinotecan. | British journal of cancer 20050905 |
| Palifermin reduces diarrhea and increases survival following irinotecan treatment in tumor-bearing DA rats. | International journal of cancer 20050901 |
| Pharmacogenomics in colorectal carcinomas: future perspectives in personalized therapy. | Journal of cellular physiology 20050901 |
| Inhibition of cell proliferation, cytotoxicity and induction of apoptosis of 1,4-bis(1-naphthyl)-2,3-dinitro-1,3-butadiene in gastrointestinal tumour cell lines and preliminary evaluation of its toxicity in vivo. | Pharmacological research 20050901 |
| Recent advances in conventional-dose salvage chemotherapy in patients with cisplatin-resistant or refractory testicular germ cell tumors. | European urology 20050901 |
| Gastric cancer. Treatment of advanced disease and new drugs. | Frontiers in bioscience : a journal and virtual library 20050901 |
| The role of thymidylate synthase and dihydropyrimidine dehydrogenase in resistance to 5-fluorouracil in human lung cancer cells. | Lung cancer (Amsterdam, Netherlands) 20050901 |
| Oxaliplatin, folinic acid and 5-fluorouracil (FOLFOX-4) combination chemotherapy as second-line treatment in advanced colorectal cancer patients with irinotecan failure: a Korean single-center experience. | Japanese journal of clinical oncology 20050901 |
| Comparison between triple therapy with octreotide, galanin and serotonin vs. irinotecan or oxaliplatin in combination with 5-fluorouracil/leukovorin in human colon cancer. | International journal of oncology 20050901 |
| Thymidylate synthase expression levels: a prognostic and predictive role in advanced colorectal cancer. | Oncology reports 20050901 |
| Synergistic interaction between oxaliplatin and SN-38 in human gastric cancer cell lines in vitro. | Oncology reports 20050901 |
| Determination of thalidomide by high performance liquid chromatography: plasma pharmacokinetic studies in the rat. | Journal of pharmaceutical and biomedical analysis 20050901 |
| Combination of trabectedin and irinotecan is highly effective in a human rhabdomyosarcoma xenograft. | Anti-cancer drugs 20050901 |
| In vitro partition of irinotecan (CPT-11) in human volunteer blood: the influence of concentration, gender and smoking. | Anti-cancer drugs 20050901 |
| Prognostic impact of race and ethnicity in the treatment of colorectal cancer. | The Medical clinics of North America 20050901 |
| Regression of colorectal adenomas with intravenous cytotoxic chemotherapy in a patient with familial adenomatous polyposis. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050901 |
| Phase I study of S-1 combined with irinotecan (CPT-11) in patients with advanced gastric cancer (OGSG 0002). | Japanese journal of clinical oncology 20050901 |
| Have we made progress in pharmacogenomics? The implementation of molecular markers in colon cancer. | Pharmacogenomics 20050901 |
| ERCC1 codon 118 polymorphism is a predictive factor for the tumor response to oxaliplatin/5-fluorouracil combination chemotherapy in patients with advanced colorectal cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050901 |
| Activity of novel cytotoxic agents in lung cancer: epothilones and topoisomerase I inhibitors. | Clinical lung cancer 20050901 |
| Phase II trial of gemcitabine/irinotecan in refractory or relapsed small-cell lung cancer. | Clinical lung cancer 20050901 |
| [Clinical evaluation of chemotherapy with irinotecan (CPT-11), l-leucovorin (l-LV), 5-fluorouracil (5-FU), and UFT for metastatic or recurrent colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20050901 |
| [Clinical significant of semiquantificating DNA topoisomerase- I mRNA in colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20050901 |
| [A case of colon cancer with liver and lung metastases-efficacy of CPT-11/5-FU/l-LV (IFL) as part of ambulatory treatment]. | Gan to kagaku ryoho. Cancer & chemotherapy 20050901 |
| Irinotecan therapy in a 12-year-old girl with recurrent brain stem glioma and without functional polymorphisms in UGT1A1 activity: case report. | Journal of neuro-oncology 20050901 |
| Analysis of prognostic factors and applicability of Kohne's prognostic groups in patients with metastatic colorectal cancer treated with first-line irinotecan or oxaliplatin-based chemotherapy. | Clinical colorectal cancer 20050901 |
| Safety and efficacy of irinotecan plus high-dose leucovorin and intravenous bolus 5-fluorouracil for metastatic colorectal cancer: pooled analysis of two consecutive southern Italy cooperative oncology group trials. | Clinical colorectal cancer 20050901 |
| [Functional SNPs of the breast cancer resistance protein (ABCG2) gene altering the pharmacokinetics/pharmacodynamics of anticancer agents]. | Seikagaku. The Journal of Japanese Biochemical Society 20050901 |
| Non-invasive fluorescence imaging of cell death in fresh human colon epithelia treated with 5-Fluorouracil, CPT-11 and/or TRAIL. | Cancer biology & therapy 20050901 |
| Irinotecan, continuous 5-fluorouracil, and low dose of leucovorin (modified FOLFIRI) as first line of therapy in recurrent or metastatic colorectal cancer. | The Korean journal of internal medicine 20050901 |
| [Successful salvage therapy of continuous low-dose irinotecan for a patient with relapsed and refractory diffuse large B-cell lymphoma]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20050901 |
| Plants as a source of anti-cancer agents. | Journal of ethnopharmacology 20050822 |
| Phase II study of gefitinib, fluorouracil, leucovorin, and oxaliplatin therapy in previously treated patients with metastatic colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050820 |
| Cetuximab therapy and symptomatic hypomagnesemia. | Journal of the National Cancer Institute 20050817 |
| Signaling through IFN regulatory factor-5 sensitizes p53-deficient tumors to DNA damage-induced apoptosis and cell death. | Cancer research 20050815 |
| Phase I/II combined chemoimmunotherapy with carcinoembryonic antigen-derived HLA-A2-restricted CAP-1 peptide and irinotecan, 5-fluorouracil, and leucovorin in patients with primary metastatic colorectal cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050815 |
| pH-dependent association of SN-38 with lipid bilayers of a novel liposomal formulation. | International journal of pharmaceutics 20050811 |
| [Clinical effects of combination chemotherapy with irinotecan hydrochloride and cisplatin on cervical cancer: study of 46 patients]. | Zhonghua yi xue za zhi 20050810 |
| Fluvastatin synergistically enhances the antiproliferative effect of gemcitabine in human pancreatic cancer MIAPaCa-2 cells. | British journal of cancer 20050808 |
| Effects of Onyx-015 among metastatic colorectal cancer patients that have failed prior treatment with 5-FU/leucovorin. | Cancer gene therapy 20050801 |
| Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: a multicenter study of the Gruppo Oncologico Dell'Italia Meridionale. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050801 |
| Phase III study of weekly high-dose infusional fluorouracil plus folinic acid with or without irinotecan in patients with metastatic colorectal cancer: European Organisation for Research and Treatment of Cancer Gastrointestinal Group Study 40986. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050801 |
| Whither irinotecan? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050801 |
| Inactivation of antineoplastics in clinical wastewater by electrolysis. | Chemosphere 20050801 |
| Phase I trial of systemic oxaliplatin combination chemotherapy with hepatic arterial infusion in patients with unresectable liver metastases from colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050801 |
| Increased anticancer activity of the thymidylate synthase inhibitor BGC9331 combined with the topoisomerase I inhibitor SN-38 in human colorectal and breast cancer cells: induction of apoptosis and ROCK cleavage through caspase-3-dependent and -independent mechanisms. | International journal of oncology 20050801 |
| Irinotecan and etoposide for previously untreated extensive-disease small cell lung cancer: a phase II trial of West Japan Thoracic Oncology Group. | Lung cancer (Amsterdam, Netherlands) 20050801 |
| Pharmacokinetic changes of irinotecan by intestinal alkalinization in an advanced colorectal cancer patient. | Therapeutic drug monitoring 20050801 |
| Pharmacokinetic profile of cetuximab (Erbitux) alone and in combination with irinotecan in patients with advanced EGFR-positive adenocarcinoma. | European journal of cancer (Oxford, England : 1990) 20050801 |
| Brain tumor oncolysis with replication-conditional herpes simplex virus type 1 expressing the prodrug-activating genes, CYP2B1 and secreted human intestinal carboxylesterase, in combination with cyclophosphamide and irinotecan. | Cancer research 20050801 |
| Pilot study of concurrent etoposide and cisplatin plus accelerated hyperfractionated thoracic radiotherapy followed by irinotecan and cisplatin for limited-stage small cell lung cancer: Japan Clinical Oncology Group 9903. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050801 |
| Phase II trial of induction gemcitabine/CPT-11 followed by a twice-weekly infusion of gemcitabine and concurrent external beam radiation for the treatment of locally advanced pancreatic cancer. | American journal of clinical oncology 20050801 |
| [Application of adenosine triphosphate tumor chemosensitive assay system to individual chemotherapy for hepatocellular carcinoma]. | Ai zheng = Aizheng = Chinese journal of cancer 20050801 |
| Bi-weekly chemotherapy of paclitaxel and cisplatin in patients with metastatic or recurrent esophageal cancer. | Journal of Korean medical science 20050801 |
| Analysis of incomplete quality of life data in advanced stage cancer: a practical application of multiple imputation. | Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 20050801 |
| Current stage-specific chemotherapeutic options in colon cancer. | Expert review of anticancer therapy 20050801 |
| [A case of advanced gastric cancer with lymphangitis carcinomatosa after operation of Krukenberg tumor treated by TS-1 plus CPT-11 as third-line chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20050801 |
| [Four cases of advanced colorectal cancer successfully treated with irinotecan plus 5-fluorouracil and l-leucovorin combination chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20050801 |
| [Oxaliplatin]. | Gan to kagaku ryoho. Cancer & chemotherapy 20050801 |
| Pharmacogenetics in gastrointestinal tumors. | Onkologie 20050801 |
| Good tolerance of weekly irinotecan in a patient with metastatic colorectal cancer on chronic hemodialysis. | Journal of chemotherapy (Florence, Italy) 20050801 |
| Patient with angina secondary to capecitabine. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20050801 |
| Metastatic colorectal cancer: is there one standard approach? | Oncology (Williston Park, N.Y.) 20050801 |
| [Pharmacological skills for targeting EGFR and VEGF]. | Bulletin du cancer 20050801 |
| [Targeting the epidermal growth factor receptor in colorectal cancer: clinical results]. | Bulletin du cancer 20050801 |
| Thymidylate synthase, thymidine phosphorylase, VEGF and p53 protein expression in primary colorectal cancer for predicting response to 5-fluorouracil-based chemotherapy. | Cancer research and treatment : official journal of Korean Cancer Association 20050801 |
| Adjuvant therapy of colon cancer: current status and future developments. | Clinics in colon and rectal surgery 20050801 |
| Simultaneous determination of the lactone and carboxylate forms of irinotecan (CPT-11) and its active metabolite SN-38 by high-performance liquid chromatography: application to plasma pharmacokinetic studies in the rat. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050725 |
| Gemcitabine with or without continuous infusion 5-FU in advanced pancreatic cancer: a randomised phase II trial of the Italian oncology group for clinical research (GOIRC). | British journal of cancer 20050725 |
| A phase II trial of TIP (paclitaxel, ifosfamide and cisplatin) given as second-line (post-BEP) salvage chemotherapy for patients with metastatic germ cell cancer: a medical research council trial. | British journal of cancer 20050725 |
| Phase II study of weekly oxaliplatin plus infusional fluorouracil and folinic acid (FUFOX regimen) as first-line treatment in metastatic gastric cancer. | British journal of cancer 20050725 |
| Capecitabine plus oxaliplatin for the first-line treatment of elderly patients with metastatic colorectal carcinoma: final results of the Southern Italy Cooperative Oncology Group Trial 0108. | Cancer 20050715 |
| A phase I clinical trial of continual alternating etoposide and topotecan in refractory solid tumours. | British journal of cancer 20050711 |
| Diffuse EGFR staining is associated with reduced overall survival in locally advanced oesophageal squamous cell cancer. | British journal of cancer 20050711 |
| Role of genomic markers in colorectal cancer treatment. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050710 |
| Systemic therapy for metastatic colorectal cancer: current options, current evidence. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050710 |
| Mitomycin-C and capecitabine as third-line chemotherapy in patients with advanced colorectal cancer: a phase II study. | Cancer chemotherapy and pharmacology 20050701 |
| Phase I clinical and pharmacokinetic trial of docetaxel and irinotecan administered on a weekly schedule. | Cancer chemotherapy and pharmacology 20050701 |
| Differential rates of glucuronidation for 7-ethyl-10-hydroxy-camptothecin (SN-38) lactone and carboxylate in human and rat microsomes and recombinant UDP-glucuronosyltransferase isoforms. | Drug metabolism and disposition: the biological fate of chemicals 20050701 |
| Synthesis and antitumor activity of the hexacyclic camptothecin derivatives. | Bioorganic & medicinal chemistry letters 20050701 |
| Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. | Journal of pharmaceutical sciences 20050701 |
| Salvage chemotherapy with irinotecan and cisplatin in patients with metastatic gastric cancer failing both 5-fluorouracil and taxanes. | Anti-cancer drugs 20050701 |
| Dosimetric correlations of acute esophagitis in lung cancer patients treated with radiotherapy. | International journal of radiation oncology, biology, physics 20050701 |
| A phase I/II and pharmacokinetic study of irinotecan in combination with capecitabine as first-line therapy for advanced colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20050701 |
| A mouse model for developing treatment for secondary liver tumors. | International journal of oncology 20050701 |
| Chemotherapy under cachectic conditions and the possibility of cachexia-controlled chemotherapy. | Oncology reports 20050701 |
| Developing new drugs for the treatment of lymphoma. | European journal of haematology. Supplementum 20050701 |
| Chemotherapy for metastatic colorectal cancer. | Journal of the National Comprehensive Cancer Network : JNCCN 20050701 |
| [Second-line chemotherapy with bi-weekly CPT-11 and cisplatin for recurrent colorectal cancer resistant to 5-FU based chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20050701 |
| [Combination chemotherapy with oral TS-1 and low-dose CPT-11 by hepatic arterial infusion for multiple hepatic metastases from colon cancer--a case report]. | Gan to kagaku ryoho. Cancer & chemotherapy 20050701 |
| [Long-term survival in a case of large bowel cancer--efficacy of CPT-11-based chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20050701 |
| [A case report of bowel obstruction due to peritonitis carcinomatosa using combined administration with CPT-11 and CDDP]. | Gan to kagaku ryoho. Cancer & chemotherapy 20050701 |
| [Childhood rhabdomyosarcoma]. | Nihon Geka Gakkai zasshi 20050701 |
| Adjuvant irinotecan regimens in combination with infusional 5-fluorouracil/leucovorin fail to improve outcomes in surgically resected colorectal cancer. | Clinical colorectal cancer 20050701 |
| Changing patterns of bone and brain metastases in patients with colorectal cancer. | Clinical colorectal cancer 20050701 |
| Selenium protects against toxicity induced by anticancer drugs and augments antitumor activity: a highly selective, new, and novel approach for the treatment of solid tumors. | Clinical colorectal cancer 20050701 |
| [Assessment of immunotoxicity of irinotecan determined by the novel method, by which productivity of TNF-alpha from whole blood is stimulated by lipopolysaccharide]. | Rinsho byori. The Japanese journal of clinical pathology 20050701 |
| [Favorable response obtained by low dose chemotherapy in an elderly patient with extensive small cell lung cancer and renal dysfunction]. | Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20050701 |
| Chemotherapy dosing in the setting of liver dysfunction. | Oncology (Williston Park, N.Y.) 20050701 |
| Phase II trial of fortnightly irinotecan (CPT-11) in the treatment of colorectal cancer patients resistant to previous fluoropyrimidine-based chemotherapy. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20050701 |
| [New oncolytic agents and immunomodulators and their application]. | Nederlands tijdschrift voor geneeskunde 20050625 |
| [Chemotherapy of patients with colorectal carcinoma]. | Nederlands tijdschrift voor geneeskunde 20050625 |
| Randomised phase II evaluation of irinotecan plus high-dose 5-fluorouracil and leucovorin (ILF) vs 5-fluorouracil, leucovorin, and etoposide (ELF) in untreated metastatic gastric cancer. | British journal of cancer 20050620 |
| Capecitabine plus docetaxel every 3 weeks in first- and second-line metastatic oesophageal cancer: final results of a phase II trial. | British journal of cancer 20050620 |
| Gene expression signatures for colorectal cancer microsatellite status and HNPCC. | British journal of cancer 20050620 |
| Impact of the extent and duration of cytoreductive surgery on postoperative hematological toxicity after intraperitoneal chemohyperthermia for peritoneal carcinomatosis. | Journal of surgical oncology 20050615 |
| Report of two protocol planned interim analyses in a randomised multicentre phase III study comparing capecitabine with fluorouracil and oxaliplatin with cisplatin in patients with advanced oesophagogastric cancer receiving ECF. | British journal of cancer 20050606 |
| Pharmacogenetic testing: proofs of principle and pharmacoeconomic implications. | Mutation research 20050603 |
| Gefitinib (Iressa, ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells. | Cancer chemotherapy and pharmacology 20050601 |
| Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: results of a randomized phase II trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050601 |
| The histone-deacetylase inhibitor SAHA potentiates proapoptotic effects of 5-fluorouracil and irinotecan in hepatoma cells. | Journal of cancer research and clinical oncology 20050601 |
| The crystal structure of the complex of the anticancer prodrug 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin (CPT-11) with Torpedo californica acetylcholinesterase provides a molecular explanation for its cholinergic action. | Molecular pharmacology 20050601 |
| Oxaliplatin plus high-dose folinic acid and 5-fluorouracil i.v. bolus (OXAFAFU) versus irinotecan plus high-dose folinic acid and 5-fluorouracil i.v. bolus (IRIFAFU) in patients with metastatic colorectal carcinoma: a Southern Italy Cooperative Oncology Group phase III trial. | Annals of oncology : official journal of the European Society for Medical Oncology 20050601 |
| Rapid up-regulation of cyclooxygenase-2 by 5-fluorouracil in human solid tumors. | Anti-cancer drugs 20050601 |
| Irinotecan or oxaliplatin combined with leucovorin and 5-fluorouracil as first-line treatment in advanced colorectal cancer: a multicenter, randomized, phase II study. | Annals of oncology : official journal of the European Society for Medical Oncology 20050601 |
| A phase I trial of irinotecan (CPT-11) with amifostine in patients with metastatic colorectal cancer. | Investigational new drugs 20050601 |
| Weekly irinotecan plus UFT and leucovorin as first-line chemotherapy of patients with advanced colorectal cancer. | Investigational new drugs 20050601 |
| Irinotecan or oxaliplatin for first-line treatment of advanced colorectal cancer? | Annals of oncology : official journal of the European Society for Medical Oncology 20050601 |
| Irinotecan for malignant mesothelioma A phase II trial by the Cancer and Leukemia Group B. | Lung cancer (Amsterdam, Netherlands) 20050601 |
| Irinotecan hydrochloride (CPT-11) and mitomycin C as the first line chemotherapy for ovarian clear cell adenocarcinoma. | Gynecologic oncology 20050601 |
| Perioperative adjunctive treatment in the management of operable gastric cancer. | Journal of surgical oncology 20050601 |
| Genome-wide expression analysis of therapy-resistant tumors reveals SPARC as a novel target for cancer therapy. | The Journal of clinical investigation 20050601 |
| [Systemic therapy for colorectal cancer]. | Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 20050601 |
| Effect of steatohepatitis associated with irinotecan or oxaliplatin pretreatment on resectability of hepatic colorectal metastases. | Journal of the American College of Surgeons 20050601 |
| A long-term survival case of small cell lung cancer in an HIV-infected patient. | Japanese journal of clinical oncology 20050601 |
| ZD6474--clinical experience to date. | British journal of cancer 20050601 |
| The realisation of targeted antitumour therapy. | British journal of cancer 20050601 |
| Role of novel targeted therapies in the clinic. | British journal of cancer 20050601 |
| Targeted antitumour therapy--future perspectives. | British journal of cancer 20050601 |
| ZD6474--a novel inhibitor of VEGFR and EGFR tyrosine kinase activity. | British journal of cancer 20050601 |
| A phase I pharmacologic and pharmacogenetic trial of sequential 24-hour infusion of irinotecan followed by leucovorin and a 48-hour infusion of fluorouracil in adult patients with solid tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050601 |
| Preclinical evaluation of gemcitabine combination regimens for application in acute myeloid leukemia. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050601 |
| [Feasibility survey (Phase I-II) of a four drugs combination (5-fluorouracil, folinic acid, carboplatin and irinotecan) delivered using a chronomodulated infusion in the treatment of advanced colorectal cancer]. | Pathologie-biologie 20050601 |
| St. John's Wort modulates the toxicities and pharmacokinetics of CPT-11 (irinotecan) in rats. | Pharmaceutical research 20050601 |
| In vitro and in vivo irinotecan-induced changes in expression profiles of cell cycle and apoptosis-associated genes in acute myeloid leukemia cells. | Molecular cancer therapeutics 20050601 |
| [Chemotherapy for advanced non-small cell lung cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20050601 |
| [Treatment of small cell lung cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20050601 |
| [New anti-cancer agents--from cytotoxic systemic chemotherapy to target-based agents]. | Gan to kagaku ryoho. Cancer & chemotherapy 20050601 |
| [Complete response of recurrent gastric cancer to chemotherapy with TS-1 and CPT-11--a case report]. | Gan to kagaku ryoho. Cancer & chemotherapy 20050601 |
| [A case of peritoneal dissemination of gastric cancer successfully treated by irinotecan combined with cisplatin]. | Gan to kagaku ryoho. Cancer & chemotherapy 20050601 |
| Beyond 5-fluorouracil: new horizons in systemic therapy for advanced colorectal cancer. | Expert opinion on investigational drugs 20050601 |
| Oxaliplatin (Eloxatin) plus irinotecan combination chemotherapy found effective in refractory metastatic insular thyroid carcinoma. | Thyroid : official journal of the American Thyroid Association 20050601 |
| Treatment of small cell lung cancer. | Seminars in respiratory and critical care medicine 20050601 |
| Modeling antitumor activity in xenograft tumor treatment. | Biometrical journal. Biometrische Zeitschrift 20050601 |
| Cetuximab: an epidermal growth factor receptor monoclonal antibody for the treatment of colorectal cancer. | Clinical therapeutics 20050601 |
| [Molecular biology in clinical cancer research: the example of digestive cancers]. | Revue d'epidemiologie et de sante publique 20050601 |
| Paclitaxel chemotherapy: from empiricism to a mechanism-based formulation strategy. | Therapeutics and clinical risk management 20050601 |
| Surface morphology control of polylactide microspheres enclosing irinotecan hydrochloride. | International journal of pharmaceutics 20050530 |
| Distinct roles for p53 transactivation and repression in preventing UCN-01-mediated abrogation of DNA damage-induced arrest at S and G2 cell cycle checkpoints. | Oncogene 20050526 |
| Gefitinib treatment affects androgen levels in non-small-cell lung cancer patients. | British journal of cancer 20050523 |
| Salvage chemotherapy with irinotecan, 5-fluorouracil and leucovorin for taxane- and cisplatin-refractory, metastatic gastric cancer. | British journal of cancer 20050523 |
| A phase II trial of gefitinib with 5-fluorouracil, leucovorin, and irinotecan in patients with colorectal cancer. | British journal of cancer 20050523 |
| Phase II study of irinotecan plus cisplatin induction followed by concurrent twice-daily thoracic irradiation with etoposide plus cisplatin chemotherapy for limited-disease small-cell lung cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050520 |
| Molecular determinants of cetuximab efficacy. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050520 |
| Irinotecan in combination with fluorouracil in a 48-hour continuous infusion as first-line chemotherapy for elderly patients with metastatic colorectal cancer: a Spanish Cooperative Group for the Treatment of Digestive Tumors study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050520 |
| A phase I clinical trial of the sequential combination of irinotecan followed by flavopiridol. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050515 |
| Preclinical relevance of dosing time for the therapeutic index of gemcitabine-cisplatin. | British journal of cancer 20050509 |
| Cooperative stimulation of vascular endothelial growth factor expression by hypoxia and reactive oxygen species: the effect of targeting vascular endothelial growth factor and oxidative stress in an orthotopic xenograft model of bladder carcinoma. | British journal of cancer 20050509 |
| Phase III study of 5FU, etoposide and leucovorin (FELV) compared to epirubicin, cisplatin and 5FU (ECF) in previously untreated patients with advanced biliary cancer. | British journal of cancer 20050509 |
| A phase II study of biweekly oxaliplatin plus infusional 5-fluorouracil and folinic acid (FOLFOX-4) as first-line treatment of advanced gastric cancer patients. | British journal of cancer 20050509 |
| Liquid chromatographic-tandem mass spectrometric assay for the simultaneous quantification of Camptosar and its metabolite SN-38 in mouse plasma and tissues. | Journal of chromatography. A 20050506 |
| Enhanced antitumor activity of irofulven in combination with irinotecan in pediatric solid tumor xenograft models. | Cancer chemotherapy and pharmacology 20050501 |
| Uptake of irinotecan metabolite SN-38 by the human intestinal cell line Caco-2. | Cancer chemotherapy and pharmacology 20050501 |
| Severe chemotherapy-induced diarrhea in patients with colorectal cancer: a cost of illness analysis. | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20050501 |
| Secretory transport of irinotecan metabolite SN-38 across isolated intestinal tissue. | Cancer chemotherapy and pharmacology 20050501 |
| Identification and characterization of a functional TATA box polymorphism of the UDP glucuronosyltransferase 1A7 gene. | Molecular pharmacology 20050501 |
| Blocking of PI3K/Akt pathway enhances apoptosis induced by SN-38, an active form of CPT-11, in human hepatoma cells. | International journal of oncology 20050501 |
| Oxaliplatin combined with irinotecan and 5-fluorouracil/leucovorin (OCFL) in metastatic colorectal cancer: a phase I-II study. | Annals of oncology : official journal of the European Society for Medical Oncology 20050501 |
| Monoclonal antibodies targeting epidermal growth factor receptor and vascular endothelial growth factor with a focus on head and neck tumors. | Current opinion in oncology 20050501 |
| A phase I, dose-finding study of irinotecan (CPT-11) short i.v. infusion combined with fixed dose of 5-fluorouracil (5-FU) protracted i.v. infusion in adult patients with advanced solid tumours. | Cancer chemotherapy and pharmacology 20050501 |
| The use of irinotecan and oxaliplatin in the treatment of advanced colorectal cancer. | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20050501 |
| First-line therapy for advanced colorectal cancer. | Current oncology reports 20050501 |
| Second-line therapy for advanced colorectal carcinoma. | Current oncology reports 20050501 |
| Chemotherapy for advanced pancreatic cancer: past, present, and future. | Current oncology reports 20050501 |
| New combinations in metastatic colorectal cancer: what are our expectations? | The oncologist 20050501 |
| 5-Fluorouracil/irinotecan induced lethal toxicity as a result of a combined pharmacogenetic syndrome: report of a case. | Journal of clinical pathology 20050501 |
| Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study. | The Lancet. Oncology 20050501 |
| Haplotypes of variants in the UDP-glucuronosyltransferase1A9 and 1A1 genes. | Pharmacogenetics and genomics 20050501 |
| Drg1 expression in 131 colorectal liver metastases: correlation with clinical variables and patient outcomes. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050501 |
| Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model. | Cancer research 20050501 |
| Adding irinotecan to first-line gemcitabine improves tumour response in advanced pancreatic cancer. | Cancer treatment reviews 20050501 |
| Combined systemic chronotherapy and hepatic artery infusion for the treatment of metastatic colorectal cancer confined to the liver. | Chemotherapy 20050501 |
| The irinotecan/5-fluorouracil combination induces apoptosis and enhances manganese superoxide dismutase activity in HT-29 human colon carcinoma cells. | Chemotherapy 20050501 |
| Molecularly targeted therapy for gastrointestinal cancer. | Current cancer drug targets 20050501 |
| Irinotecan pharmacokinetic and pharmacogenomic alterations induced by methylselenocysteine in human head and neck xenograft tumors. | Molecular cancer therapeutics 20050501 |
| FOLFIRI regimen in advanced colorectal cancer: the experience of the Gruppo Oncologico dell'Italia Meridionale (GOIM). | Annals of oncology : official journal of the European Society for Medical Oncology 20050501 |
| Adjuvant therapy in colon cancer: which treatment in 2005? | Annals of oncology : official journal of the European Society for Medical Oncology 20050501 |
| Results of a phase II open-label study of capecitabine in combination with irinotecan as first-line treatment for metastatic colorectal cancer. | Clinical colorectal cancer 20050501 |
| Severe irinotecan-induced toxicities in a patient with uridine diphosphate glucuronosyltransferase 1A1 polymorphism. | Clinical colorectal cancer 20050501 |
| [Irinotecan combined with fluoropyrimidine in treatment for advanced/metastatic colorectal carcinoma]. | Zhonghua wai ke za zhi [Chinese journal of surgery] 20050501 |
| [Prognostic value of thymidylate synthase, topoisomerase-1 and Ki-67 in advanced colorectal cancer patients on irinotecan and fluorouracil treatment]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20050501 |
| [Successful treatment of refractory mantle cell lymphoma with irinotecan]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20050501 |
| HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo. | British journal of cancer 20050425 |
| Intensified concurrent chemoradiotherapy with 5-fluorouracil and irinotecan as neoadjuvant treatment in patients with locally advanced rectal cancer. | British journal of cancer 20050411 |
| Thromboembolic events in gastric cancer: high incidence in patients receiving irinotecan- and bevacizumab-based therapy. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050410 |
| The role of checkpoint kinase 1 in sensitivity to topoisomerase I poisons. | The Journal of biological chemistry 20050408 |
| [Colon cancer: molecular markers]. | Deutsche medizinische Wochenschrift (1946) 20050408 |
| Discovery of a fluoroindolo[2,3-a]carbazole clinical candidate with broad spectrum antitumor activity in preclinical tumor models superior to the marketed oncology drug, CPT-11. | Journal of medicinal chemistry 20050407 |
| Anti-angiogenic effects of SN38 (active metabolite of irinotecan): inhibition of hypoxia-inducible factor 1 alpha (HIF-1alpha)/vascular endothelial growth factor (VEGF) expression of glioma and growth of endothelial cells. | Journal of cancer research and clinical oncology 20050401 |
| Carcinoembryonic antigen antibody inhibits lung metastasis and augments chemotherapy in a human colonic carcinoma xenograft. | Cancer immunology, immunotherapy : CII 20050401 |
| Cerebrospinal fluid-disseminated meningioma. | Cancer 20050401 |
| Tumor necrosis factor enhances SN38-mediated apoptosis in mesothelioma cells: the role of nuclear factor-kappaB pathway activation. | Cancer 20050401 |
| Gefitinib ('Iressa', ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells. | Cancer chemotherapy and pharmacology 20050401 |
| Irinotecan combined or alternated with bolus 5-fluorouracil and folinic acid versus the Mayo Clinic regimen in the first-line therapy of advanced colorectal cancer. | Oncology reports 20050401 |
| Phase I study of combination chemotherapy with gemcitabine and irinotecan for non-small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20050401 |
| Pharmacogenetic profiling across the irinotecan pathway in Asian patients with cancer. | British journal of clinical pharmacology 20050401 |
| Critical evaluation of current treatments in metastatic colorectal cancer. | The oncologist 20050401 |
| Expression of multidrug transporter MRP4/ABCC4 is a marker of poor prognosis in neuroblastoma and confers resistance to irinotecan in vitro. | Molecular cancer therapeutics 20050401 |
| Phase II study of irinotecan, 5-fluorouracil and leucovorin as first-line therapy for advanced colorectal cancer. | Japanese journal of clinical oncology 20050401 |
| Complete response of brain metastases to irinotecan-based chemotherapy. | Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20050401 |
| [A case of recurrent breast cancer with bone metastasis causing pancytopenia--efficacy of low-dose CPT-11+ MPA]. | Gan to kagaku ryoho. Cancer & chemotherapy 20050401 |
| Irinotecan-induced colitis. | International journal of surgical pathology 20050401 |
| Epidermal growth factor receptor as a target for chemotherapy. | Clinical colorectal cancer 20050401 |
| Cetuximab in previously treated colorectal cancer. | Clinical colorectal cancer 20050401 |
| Irinotecan-based regimens in the adjuvant therapy of colorectal cancer. | Clinical colorectal cancer 20050401 |
| [A young patient with invasive small cell carcinoma of the urinary bladder: a case report]. | Hinyokika kiyo. Acta urologica Japonica 20050401 |
| Phase II study of irinotecan, leucovorin, 5-fluorouracil and tegafur/uracil for metastatic colorectal cancer. | Journal of chemotherapy (Florence, Italy) 20050401 |
| Current therapies for advanced colorectal cancer. | Oncology (Williston Park, N.Y.) 20050401 |
| Management of advanced colorectal cancer in older patients. | Oncology (Williston Park, N.Y.) 20050401 |
| Docetaxel in the management of advanced pancreatic cancer. | Seminars in oncology 20050401 |
| Experience with docetaxel in the treatment of gastric cancer. | Seminars in oncology 20050401 |
| Docetaxel in the treatment of esophageal cancer. | Seminars in oncology 20050401 |
| Combination of gemcitabine and irinotecan for recurrent metastatic osteogenic sarcoma. | Clinical advances in hematology & oncology : H&O 20050401 |
| Cetuximab in the treatment of colorectal cancer. | Future oncology (London, England) 20050401 |
| Chemotherapy for advanced gastric cancer: slow but further progress. | Cancer research and treatment : official journal of Korean Cancer Association 20050401 |
| Optimisation of irinotecan dose in the treatment of patients with metastatic colorectal cancer after 5-FU failure: results from a multinational, randomised phase II study. | British journal of cancer 20050328 |
| Engineering and characterisation of chimeric monoclonal antibody 806 (ch806) for targeted immunotherapy of tumours expressing de2-7 EGFR or amplified EGFR. | British journal of cancer 20050328 |
| Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050320 |
| Is there a new drug beyond floxuridine for intra-arterial hepatic chemotherapy in liver metastases from colorectal cancer? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050320 |
| A phase I clinical and pharmacokinetic study of capecitabine (Xeloda) and irinotecan combination therapy (XELIRI) in patients with metastatic gastrointestinal tumours. | British journal of cancer 20050314 |
| Australian experience of a modified schedule of FOLFOX with high activity and tolerability and improved convenience in untreated metastatic colorectal cancer patients. | British journal of cancer 20050314 |
| Adenoviral vector-mediated expression of a gene encoding secreted, EpCAM-targeted carboxylesterase-2 sensitises colon cancer spheroids to CPT-11. | British journal of cancer 20050314 |
| In vivo efficacy of HSV-TK transcriptionally targeted to the tumour vasculature is augmented by combination with cytotoxic chemotherapy. | The journal of gene medicine 20050301 |
| Racial variability in haplotype frequencies of UGT1A1 and glucuronidation activity of a novel single nucleotide polymorphism 686C> T (P229L) found in an African-American. | Drug metabolism and disposition: the biological fate of chemicals 20050301 |
| Phase I study of an oral formulation of irinotecan administered daily for 14 days every 3 weeks in patients with advanced solid tumours. | Cancer chemotherapy and pharmacology 20050301 |
| Role of organic anion transporter OATP1B1 (OATP-C) in hepatic uptake of irinotecan and its active metabolite, 7-ethyl-10-hydroxycamptothecin: in vitro evidence and effect of single nucleotide polymorphisms. | Drug metabolism and disposition: the biological fate of chemicals 20050301 |
| Chemotherapy permits resection of metastatic colorectal cancer: experience from Intergroup N9741. | Annals of oncology : official journal of the European Society for Medical Oncology 20050301 |
| Phase I trial of capecitabine and weekly irinotecan in combination with radiotherapy for neoadjuvant therapy of rectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050301 |
| From molecular characteristics to cellular events in apoptosis-resistant HL-60 cells. | International journal of oncology 20050301 |
| [Pharmacogenetics of anticancer drugs]. | Pathologie-biologie 20050301 |
| Gene expression profiling of the irinotecan pathway in colorectal cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050301 |
| Advances in colon cancer chemotheapy: nursing implications. | Home healthcare nurse 20050301 |
| Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays. | Molecular cancer therapeutics 20050301 |
| Sequential treatment with irinotecan and doxifluridine: optimal dosing schedule in murine models and in a phase I study for metastatic colorectal cancer. | Chemotherapy 20050301 |
| Gastrointestinal Cancers--Second Annual Symposium. 27-29 January 2005, Hollywood, FL, USA. | IDrugs : the investigational drugs journal 20050301 |
| [Induction of CPT-11 in a patient on hemodialysis with metastatic rectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20050301 |
| The effect of granisetron on in vitro metabolism of doxorubicin, irinotecan and etoposide. | Current medical research and opinion 20050301 |
| Classification and occurrence of clinically significant drug interactions with irinotecan and oxaliplatin in patients with metastatic colorectal cancer. | Clinical therapeutics 20050301 |
| Synthesis and antitumor activity of A-ring modified hexacyclic analogues of camptothecin. | Yao xue xue bao = Acta pharmaceutica Sinica 20050301 |
| Alternative administration of camptothecin analogues. | Expert opinion on drug delivery 20050301 |
| Clinical outcomes and management of mechanism-based inhibition of cytochrome P450 3A4. | Therapeutics and clinical risk management 20050301 |
| Oxaliplatin combined with infusional 5-fluorouracil and concomitant radiotherapy in inoperable and metastatic rectal cancer: a phase I trial. | British journal of cancer 20050227 |
| Antitumour activity of XR5944 in vitro and in vivo in combination with 5-fluorouracil and irinotecan in colon cancer cell lines. | British journal of cancer 20050227 |
| Modification of interleukin-15 serum levels in workers exposed to chemotherapeutic agents. | Mediators of inflammation 20050224 |
| Irinotecan plus oxaliplatin and leucovorin-modulated fluorouracil in advanced pancreatic cancer--a Groupe Tumeurs Digestives of the Federation Nationale des Centres de Lutte Contre le Cancer study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050220 |
| Prognostic factors in cytokine-refractory renal cell carcinoma treated with irinotecan, Cisplatin, and mitomycin chemotherapy. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050220 |
| Five-day courses of irinotecan as palliative therapy for patients with neuroblastoma. | Cancer 20050215 |
| Gefitinib ('Iressa', ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, reverses breast cancer resistance protein/ABCG2-mediated drug resistance. | Cancer research 20050215 |
| Phase I pharmacokinetic, food effect, and pharmacogenetic study of oral irinotecan given as semisolid matrix capsules in patients with solid tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050215 |
| Effects of nonselective cyclooxygenase inhibition with low-dose ibuprofen on tumor growth, angiogenesis, metastasis, and survival in a mouse model of colorectal cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050215 |
| MEN4901/T-0128, a new camptothecin derivative-carboxymethyldextran conjugate, has potent antitumor activities in a panel of human tumor xenografts in nude mice. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050215 |
| Association between intratumoral free and total VEGF, soluble VEGFR-1, VEGFR-2 and prognosis in breast cancer. | British journal of cancer 20050214 |
| Non-small-cell lung cancer in a French department, (1982-1997): management and outcome. | British journal of cancer 20050214 |
| Identification of a novel cardenolide (2''-oxovoruscharin) from Calotropis procera and the hemisynthesis of novel derivatives displaying potent in vitro antitumor activities and high in vivo tolerance: structure-activity relationship analyses. | Journal of medicinal chemistry 20050210 |
| A simple and sensitive LC/MS/MS assay for 7-ethyl-10-hydroxycamptothecin (SN-38) in mouse plasma and tissues: application to pharmacokinetic study of liposome entrapped SN-38 (LE-SN38). | Journal of pharmaceutical and biomedical analysis 20050207 |
| Systemic therapy for colorectal cancer. | The New England journal of medicine 20050203 |
| Phase II study of irinotecan (CPT-11) as salvage therapy for advanced nasopharyngeal carcinoma. | Cancer 20050201 |
| Herb-drug interactions: an overview of the clinical evidence. | Fundamental & clinical pharmacology 20050201 |
| A randomized phase II trial of capecitabine and two different schedules of irinotecan in first-line treatment of metastatic colorectal cancer: efficacy, quality-of-life and toxicity. | Annals of oncology : official journal of the European Society for Medical Oncology 20050201 |
| Comparison of docetaxel and docetaxel-irinotecan combination as second-line chemotherapy in advanced non-small-cell lung cancer: a randomized phase II trial. | Annals of oncology : official journal of the European Society for Medical Oncology 20050201 |
| Phase I and pharmacokinetic study of oral irinotecan given once daily for 5 days every 3 weeks in combination with capecitabine in patients with solid tumors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050201 |
| Management of chemotherapy-induced nausea, vomiting, oral mucositis, and diarrhoea. | The Lancet. Oncology 20050201 |
| A case of Bowen's disease and small-cell lung carcinoma: long-term consequences of chronic arsenic exposure in Chinese traditional medicine. | Environmental health perspectives 20050201 |
| Phase II study of oral S-1 plus irinotecan in patients with advanced colorectal cancer: Hokkaido Gastrointestinal Cancer Study Group HGCSG0302. | Japanese journal of clinical oncology 20050201 |
| UGT1A7 and UGT1A9 polymorphisms predict response and toxicity in colorectal cancer patients treated with capecitabine/irinotecan. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050201 |
| Molecular imaging of antiangiogenic agents. | The oncologist 20050201 |
| Cancer pharmacogenomics: powerful tools in cancer chemotherapy and drug development. | The oncologist 20050201 |
| Screening of brain metastasis with limited magnetic resonance imaging (MRI): clinical implications of using limited brain MRI during initial staging for non-small cell lung cancer patients. | Journal of Korean medical science 20050201 |
| Oral capecitabine: bridging the Atlantic divide in colon cancer treatment. | Seminars in oncology 20050201 |
| Adjuvant therapy of colon cancer. | Seminars in oncology 20050201 |
| Combined modality treatment for rectal cancer. | Seminars in oncology 20050201 |
| Pharmacogenetic influences on treatment response and toxicity in colorectal cancer. | Seminars in oncology 20050201 |
| Intratumoral molecular or genetic markers as predictors of clinical outcome with chemotherapy in colorectal cancer. | Seminars in oncology 20050201 |
| Estimating the cost of illness in colorectal cancer patients who were hospitalized for severe chemotherapy-induced diarrhea. | Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20050201 |
| Inhibitory effects of asiatic acid and CPT-11 on growth of HT-29 cells. | The journal of medical investigation : JMI 20050201 |
| Therapeutic options in the management of colon cancer: 2005 update. | Clinical journal of oncology nursing 20050201 |
| Available options in chemotherapy for advanced gastric cancer: the current developments in Japan. | Expert opinion on pharmacotherapy 20050201 |
| Cetuximab: an epidermal growth factor receptor chemeric human-murine monoclonal antibody. | Drugs of today (Barcelona, Spain : 1998) 20050201 |
| Isolated hepatic perfusion for the treatment of patients with colorectal cancer liver metastases after irinotecan-based therapy. | Annals of surgical oncology 20050201 |
| Treatment of a Gilbert's syndrome patient with irinotecan, leucovorin and 5-fluorouracil. | Journal of chemotherapy (Florence, Italy) 20050201 |
| Cytotoxic and antiangiogenic activity of AW464 (NSC 706704), a novel thioredoxin inhibitor: an in vitro study. | British journal of cancer 20050131 |
| Phase II study of capecitabine and cisplatin as first-line combination therapy in patients with gastric cancer recurrent after fluoropyrimidine-based adjuvant chemotherapy. | British journal of cancer 20050131 |
| Unfavourable expression of pharmacologic markers in mucinous colorectal cancer. | British journal of cancer 20050131 |
| [Stomach cancer]. | La Revue du praticien 20050131 |
| Intensive systemic chemotherapy combined with surgery for metastatic colorectal cancer: results of a phase II study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050120 |
| Relationship of serum bilirubin to toxicity in patients with metastatic colorectal cancer treated with single-agent high-dose irinotecan. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050120 |
| A randomised phase II trial of docetaxel vs docetaxel and irinotecan in patients with stage IIIb-IV non-small-cell lung cancer who failed first-line treatment. | British journal of cancer 20050117 |
| Adjuvant sequential methotrexate --> 5-fluorouracil vs 5-fluorouracil plus leucovorin in radically resected stage III and high-risk stage II colon cancer. | British journal of cancer 20050117 |
| Repeated-measures models with constrained parameters for incomplete data in tumour xenograft experiments. | Statistics in medicine 20050115 |
| Phase II trial of irinotecan plus celecoxib in adults with recurrent malignant glioma. | Cancer 20050115 |
| Estrogen-mediated post transcriptional down-regulation of breast cancer resistance protein/ABCG2. | Cancer research 20050115 |
| Role of temozolomide after radiotherapy for newly diagnosed diffuse brainstem glioma in children: results of a multiinstitutional study (SJHG-98). | Cancer 20050101 |
| Efficacy of the third-generation bisphosphonate, zoledronic acid alone and combined with anti-cancer agents against small cell lung cancer cell lines. | Lung cancer (Amsterdam, Netherlands) 20050101 |
| Irinotecan (CPT-11)-based chemotherapy as induction treatment for advanced colorectal cancer. | Anti-cancer drugs 20050101 |
| Irinotecan and capecitabine as second-line treatment after failure for first-line infusional 24-h 5-fluorouracil/folinic acid in advanced colorectal cancer: a phase II study. | Anti-cancer drugs 20050101 |
| Statistical validation of the EORTC prognostic model for malignant pleural mesothelioma based on three consecutive phase II trials. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050101 |
| Loperamide inhibits the biliary excretion of irinotecan (CPT-11) in the rat isolated perfused liver. | The Journal of pharmacy and pharmacology 20050101 |
| Effect of carboxylesterase inhibition on the anti-tumour effects of irinotecan. | The Journal of international medical research 20050101 |
| Synergistic antitumor activity of capecitabine in combination with irinotecan. | Clinical colorectal cancer 20050101 |
| Importance of preclinical investigations of the integration of capecitabine into polychemotherapy regimens. | Clinical colorectal cancer 20050101 |
| [Second-line chemotherapy for advanced colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20050101 |
| [Second-line chemotherapy for recurrent ovarian cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20050101 |
| [The second-line chemotherapy for urological cancers]. | Gan to kagaku ryoho. Cancer & chemotherapy 20050101 |
| [A patient with recurrent gallbladder cancer responding to chemotherapy with CDDP/CPT-11 and gemcitabine]. | Gan to kagaku ryoho. Cancer & chemotherapy 20050101 |
| Topoisomerases in the treatment of metastatic or recurrent squamous carcinoma of the head and neck. | Expert opinion on pharmacotherapy 20050101 |
| Toxicity of the topoisomerase I inhibitors. | Expert opinion on drug safety 20050101 |
| Chemoresistance in non-small cell lung cancer. | Current medicinal chemistry. Anti-cancer agents 20050101 |
| New drugs for colorectal cancer (irinotecan, oxaliplatin, raltitrexed) meet expectations in routine practice: a single center's experience before and after their introduction. | International journal of gastrointestinal cancer 20050101 |
| Pharmacogenomics of fluorouracil, irinotecan, and oxaliplatin in hepatic metastases of colorectal cancer: clinical implications. | American journal of pharmacogenomics : genomics-related research in drug development and clinical practice 20050101 |
| Small-cell lung cancer: current therapy and novel agents. | Oncology (Williston Park, N.Y.) 20050101 |
| Drug bioactivation, covalent binding to target proteins and toxicity relevance. | Drug metabolism reviews 20050101 |
| Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs. | Clinical pharmacokinetics 20050101 |
| Capecitabine: a review. | Clinical therapeutics 20050101 |
| Third-line chemotherapy with paclitaxel, irinotecan hydrochloride and cisplatin for recurrent gastric cancer: a case report. | Hepato-gastroenterology 20050101 |
| First-line treatment with irinotecan and raltitrexed in metastatic colorectal cancer. Mature results of a multicenter phase II study. | Oncology 20050101 |
| Response to temozolomide in second-line treatment of recurrent nonsmall cell lung carcinoma: case report. | Cancer investigation 20050101 |
| Preclinical safety, pharmacokinetics and antitumor efficacy profile of liposome-entrapped SN-38 formulation. | Anticancer research 20050101 |
| Selenium supplementation may increase the efficacy of cetuximab in metastatic colorectal cancer patients. | Medical hypotheses 20050101 |
| Benefit-risk assessment of irinotecan in advanced colorectal cancer. | Drug safety 20050101 |
| Genetic polymorphism in the phenobarbital-responsive enhancer module of the UDP-glucuronosyltransferase 1A1 gene and irinotecan toxicity. | Pharmacogenetics and genomics 20050101 |
| Current status and future prospects of chemotherapy for metastatic gastric cancer: a review. | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20050101 |
| Neoadjuvant radiotherapy and radiochemotherapy for rectal cancer. | Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20050101 |
| Indications and effect on survival of standard chemotherapy in advanced colorectal cancer. | Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20050101 |
| New chemotherapeutic strategies in colorectal cancer. | Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20050101 |
| Phase 1/11 study of bi-weekly irinotecan plus cisplatin in the treatment of advanced gastric cancer. | Anticancer research 20050101 |
| Phase II trial of irinotecan and raltitrexed in chemotherapy-naive advanced colorectal cancer. | Anticancer research 20050101 |
| Pre-clinical evaluation of the activity of irinotecan as a basis for regional chemotherapy. | Anticancer research 20050101 |
| (Neo-)adjuvant treatments in colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20050101 |
| Irinotecan plus cisplatin combination against metastatic gastric cancer: phase II study. | Medical oncology (Northwood, London, England) 20050101 |
| Prognostic impact of epidermal growth factor receptor (EGFR) expression on loco-regional recurrence after preoperative radiotherapy in rectal cancer. | BMC cancer 20050101 |
| Phase I study of concomitant chemoradiotherapy with irinotecan, 5-FU, and hydroxyurea for patients with advanced and/or recurrent head and neck cancer. | Cancer journal (Sudbury, Mass.) 20050101 |
| Novel agents that potentially inhibit irinotecan-induced diarrhea. | Current medicinal chemistry 20050101 |
| Determinants of cisplatin and irinotecan activities in human lung adenocarcinoma cells: evidence of cisplatin accumulation and topoisomerase I activity. | In vivo (Athens, Greece) 20050101 |
| The role of 5-fluorouracil (5-FU) reintroduction with irinotecan or oxaliplatin in truly 5-FU-refractory advanced colorectal cancer patients. | Oncology 20050101 |
| Prospective, double-blind, placebo-controlled, multicenter, randomized phase III study with orally administered budesonide for prevention of irinotecan (CPT-11)-induced diarrhea in patients with advanced colorectal cancer. | Oncology 20050101 |
| Biweekly docetaxel-irinotecan treatment with filgrastim support is highly active in antracycline-Paclitaxel-refractory breast cancer patients. | Oncology 20050101 |
| Cancer cell adaptation to chemotherapy. | BMC cancer 20050101 |
| Brain metastases in breast cancer--an in vitro study to evaluate new systemic chemotherapeutic options. | Anticancer research 20050101 |
| Overcoming cisplatin resistance by mTOR inhibitor in lung cancer. | Molecular cancer 20050101 |
| Phase I dose-escalating study of docetaxel in combination with 5-day continuous infusion of 5-fluorouracil in patients with advanced gastric cancer. | BMC cancer 20050101 |
| Multicenter phase II study of oral capecitabine plus irinotecan as first-line chemotherapy in advanced colorectal cancer: a Korean Cancer Study Group trial. | Acta oncologica (Stockholm, Sweden) 20050101 |
| Capecitabine as third line therapy in patients with advanced colorectal cancer. | Acta oncologica (Stockholm, Sweden) 20050101 |
| Phase I study of irinotecan and amrubicin in patients with advanced non-small-cell lung cancer. | Anticancer research 20050101 |
| Exogenous expression of hRFI induces multidrug resistance through escape from apoptosis in colorectal cancer cells. | Anticancer research 20050101 |
| Pharmacokinetics and metabolism of irinotecan combined with capecitabine in patients with advanced colorectal cancer. | Anticancer research 20050101 |
| Nuclear area is a prognostic determinant in advanced colorectal cancer. | Anticancer research 20050101 |
| Continuous infusion of oxaliplatin plus chronomodulated capecitabine in 5-fluorouracil- and irinotecan-resistant advanced colorectal cancer patients. | Oncology 20050101 |
| A phase II trial of irinotecan, 5-fluorouracil and leucovorin combined with celecoxib and glutamine as first-line therapy for advanced colorectal cancer. | Oncology 20050101 |
| Transfection assays with allele-specific constructs: functional analysis of UDP-glucuronosyltransferase variants. | Methods in molecular biology (Clifton, N.J.) 20050101 |
| Circulating vascular endothelial growth factor and interferon-gamma-inducible protein-10 levels in pancreatic cancer during chemotherapy. | Anticancer research 20050101 |
| Successful analysis of anticancer drug sensitivity by CD-DST using pleural fluid and ascites from patients with advanced ovarian cancer: case reports. | Anticancer research 20050101 |
| Docetaxel in combination with irinotecan (CPT-11) in platinum-resistant paclitaxel-pretreated ovarian cancer. | Anticancer research 20050101 |
| Bevacizumab as treatment for chemotherapy-resistant pancreatic cancer. | Anticancer research 20050101 |
| A phase II study of dose-intensified weekly concomitant administration of cisplatin and irinotecan in chemonaive patients with extensive-disease small-cell lung cancer. | Medical oncology (Northwood, London, England) 20050101 |
| Liver resection after irinotecan, 5-fluorouracil, and folinic acid for patients with unresectable colorectal liver metastases: a multicenter phase II study by the Cancer Therapeutic Research Group. | Medical oncology (Northwood, London, England) 20050101 |
| Survey of oxaliplatin-associated neurotoxicity using an interview-based questionnaire in patients with metastatic colorectal cancer. | BMC cancer 20050101 |
| [Utilizing synergism]. | Krankenpflege Journal 20050101 |
| Pre-exenterative chemotherapy, a novel therapeutic approach for patients with persistent or recurrent cervical cancer. | BMC cancer 20050101 |
| Clinical trial designs for prospective validation of biomarkers. | American journal of pharmacogenomics : genomics-related research in drug development and clinical practice 20050101 |
| A prospective evaluation of treatment with Selective Internal Radiation Therapy (SIR-spheres) in patients with unresectable liver metastases from colorectal cancer previously treated with 5-FU based chemotherapy. | BMC cancer 20050101 |
| Acute presentation of rheumatoid arthritis following cancer chemotherapy using the topoisomerase I inhibitor irinotecan. | Acta oncologica (Stockholm, Sweden) 20050101 |
| Clinical pharmacogenetics of irinotecan (CPT-11). | Drug metabolism reviews 20050101 |
| Concomitant administration of bevacizumab, irinotecan, 5-fluorouracil, and leucovorin: nonclinical safety and pharmacokinetics. | International journal of toxicology 20050101 |
| Can the addition of cetuximab to irinotecan improve outcome in colorectal cancer? | Nature clinical practice. Oncology 20050101 |
| Can the addition of cetuximab to irinotecan improve outcome in colorectal cancer? | Nature clinical practice. Gastroenterology & hepatology 20050101 |
| Irinotecan and oxaliplatin combination, as second-line treatment, in fluoropyrimidine-pretreated advanced colorectal cancer. A phase II study by the Hellenic Cooperative Oncology Group (HeCOG). | Tumori 20050101 |
| High salt culture conditions suppress proliferation of rat C6 glioma cell by arresting cell-cycle progression at S-phase. | Journal of molecular neuroscience : MN 20050101 |
| An alternating regimen of irinotecan/ 5-fluorouracil/folinic acid and oxaliplatin/ 5-fluorouracil/folinic acid in metastatic colorectal cancer: a Phase II trial. | Oncology 20050101 |
| Combination chemotherapy in advanced small bowel adenocarcinoma. | Oncology 20050101 |
| [Biotherapy in colorectal cancer]. | Journal de chirurgie 20050101 |
| Bevacizumab combined with standard fluoropyrimidine-based chemotherapy regimens to treat colorectal cancer. | Oncology 20050101 |
| Same-day pegfilgrastim and chemotherapy. | Cancer investigation 20050101 |
| Combination of irinotecan (CPT-11) plus 5-fluorouracil and leucovorin (FOLFIRI regimen) as first line treatment for elderly patients with metastatic colorectal cancer: a phase II trial. | Oncology 20050101 |
| Survival after oxaliplatin therapy of irinotecan-pretreated advanced colorectal cancer patients. | Hepato-gastroenterology 20050101 |
| [Irinotecan in combination with 5-fluorouracil and leucovorin in the treatment of metastatic colorectal cancer]. | Casopis lekaru ceskych 20050101 |
| Primary undifferentiated carcinoma arising from the retroperitoneum: a case report. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20050101 |
| Progresses in the medical treatment of advanced colorectal cancer. | Roczniki Akademii Medycznej w Bialymstoku (1995) 20050101 |
| Advances in the treatment of metastatic colorectal cancer. | The oncologist 20050101 |
| Evolving chemotherapy for advanced gastric cancer. | The oncologist 20050101 |
| SW-620 cells treated with topoisomerase I inhibitor SN-38: gene expression profiling. | Journal of translational medicine 20050101 |
| Preoperative chemotherapy with irinotecan and mitomycin for FIGO stage IIIb cervical squamous cell carcinoma: a pilot study. | European journal of gynaecological oncology 20050101 |
| Chemotherapy for colorectal cancer. | Digestive surgery 20050101 |
| Irinotecan/5-fluorouracil combination induces alterations in mitochondrial membrane potential and caspases on colon cancer cell lines. | Oncology research 20050101 |
| [New chances in therapy of gastrointestinal tumors]. | Krankenpflege Journal 20050101 |
| [The results of cetuximab treatment of a patient with multiple pretreated, irinotecan resistant metastatic colorectal cancer]. | Magyar onkologia 20050101 |
| Molecular characterization of established human colon carcinoma cell lines (HCT-8) made resistant to 5-fluorouracil by different selection schedules. | Oncology research 20050101 |
| Irinotecan plus weekly 5-fluorouracil and leucovorin as salvage treatment for patients with metastatic colorectal cancer: A phase II trial. | Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20050101 |
| [Chemotherapy of advanced stomach cancer]. | Zhonghua yi xue za zhi 20041217 |
| Elimination of hepatic metastases of colon cancer cells via p53-independent cross-talk between irinotecan and Apo2 ligand/TRAIL. | Cancer research 20041215 |
| HPC1/RNASEL mediates apoptosis of prostate cancer cells treated with 2',5'-oligoadenylates, topoisomerase I inhibitors, and tumor necrosis factor-related apoptosis-inducing ligand. | Cancer research 20041215 |
| Phase II study of irinotecan combined with carboplatin in previously untreated non-small-cell lung cancer. | Cancer chemotherapy and pharmacology 20041201 |
| Two schedules of second-line irinotecan for metastatic colon carcinoma. | Cancer 20041201 |
| Bevacizumab in combination with irinotecan plus fluorouracil plus leucovorin chemotherapy prolongs survival but increases adverse events in people with metastatic colorectal cancer. | Cancer treatment reviews 20041201 |
| Gene expression profiles of colorectal carcinoma in response to neo-adjuvant chemotherapy. | International journal of oncology 20041201 |
| Suppressive effect of CPT-11 on rat esophageal tumorigenesis induced by N-nitrosomethylbenzylamine. | Oncology reports 20041201 |
| Long-term survival of patients with advanced colorectal cancer may not be due to the response to chemotherapy. | Oncology reports 20041201 |
| First-line treatment of metastatic colorectal cancer with irinotecan, oxaliplatin and 5-fluorouracil/leucovorin (FOLFOXIRI): results of a phase II study with a simplified biweekly schedule. | Annals of oncology : official journal of the European Society for Medical Oncology 20041201 |
| Irinotecan in combination with 5-fluorouracil and folinic acid or with cisplatin in patients with advanced gastric or esophageal-gastric junction adenocarcinoma: results of a randomized phase II study. | Annals of oncology : official journal of the European Society for Medical Oncology 20041201 |
| Second-line chemotherapy with irinotecan plus carmustine in glioblastoma recurrent or progressive after first-line temozolomide chemotherapy: a phase II study of the Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO). | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20041201 |
| Tumor progression while on chemotherapy: a contraindication to liver resection for multiple colorectal metastases? | Annals of surgery 20041201 |
| Which drug combination for colorectal cancer? | Expert opinion on pharmacotherapy 20041201 |
| Proteasomal degradation of topoisomerase I is preceded by c-Jun NH2-terminal kinase activation, Fas up-regulation, and poly(ADP-ribose) polymerase cleavage in SN38-mediated cytotoxicity against multiple myeloma. | Cancer research 20041201 |
| [Clinical pathway based on evidence-based medicine (EBM) for chemotherapy for lung cancer]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20041201 |
| Atazanavir for the treatment of human immunodeficiency virus infection. | Pharmacotherapy 20041201 |
| Lack of microvessels in well-differentiated regions of human head and neck squamous cell carcinoma A253 associated with functional magnetic resonance imaging detectable hypoxia, limited drug delivery, and resistance to irinotecan therapy. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041201 |
| Pharmacogenetics of human carboxylesterase 2, an enzyme involved in the activation of irinotecan into SN-38. | Clinical pharmacology and therapeutics 20041201 |
| [Colorectal cancer: current treatment options]. | Zeitschrift fur Gastroenterologie 20041201 |
| Capecitabine: the new generation of fluoropyrimidines in colorectal cancer. | Expert review of anticancer therapy 20041201 |
| Bevacizumab for advanced colorectal cancer. | Issues in emerging health technologies 20041201 |
| Chemoradiotherapy for lung cancer: current status and perspectives. | International journal of clinical oncology 20041201 |
| A phase I-II, dose-escalating trial of ZD9331 in combination with irinotecan (CPT11) in previously pretreated metastatic colorectal cancer patients. | Bulletin du cancer 20041201 |
| [Topoisomerase I inhibitor (irinotecan hydrochloride)]. | Nihon rinsho. Japanese journal of clinical medicine 20041201 |
| Irinotecan and other agents in the management of multiple tumor types. Highlights from the 6th University of Texas M. D. Anderson Cancer Center Investigators' Workshop. July 16-20, 2003, Amelia Island, Florida, USA. | Oncology (Williston Park, N.Y.) 20041201 |
| Irinotecan and carboplatin in metastatic or recurrent NSCLC: an update. | Oncology (Williston Park, N.Y.) 20041201 |
| Phase II trial of weekly irinotecan/cisplatin in advanced esophageal cancer. | Oncology (Williston Park, N.Y.) 20041201 |
| Irinotecan and 5-FU/ leucovorin in metastatic colorectal cancer: balancing efficacy, toxicity, and logistics. | Oncology (Williston Park, N.Y.) 20041201 |
| Concurrent RT with 5-FU/epirubicin and cisplatin or irinotecan for locally advanced upper GI adenocarcinoma. | Oncology (Williston Park, N.Y.) 20041201 |
| Gemcitabine/Irinotecan/celecoxib in pancreatic cancer. | Oncology (Williston Park, N.Y.) 20041201 |
| Irinotecan, epirubicin, and capecitabine in metastatic adenocarcinomas: preliminary results of a phase I study. | Oncology (Williston Park, N.Y.) 20041201 |
| Combined-modality therapy of rectal cancer with irinotecan-based regimens. | Oncology (Williston Park, N.Y.) 20041201 |
| Perspectives in the treatment of colorectal cancer. | Seminars in oncology 20041201 |
| Phase II study of nedaplatin and irinotecan for elderly patients with advanced non-small cell lung cancer. | Journal of experimental therapeutics & oncology 20041201 |
| [Molecular biology methods in cancer medicine: options beyond steel instrument, ray and chemotherapy]. | MMW Fortschritte der Medizin 20041118 |
| Mortality associated with daily bolus 5-fluorouracil/leucovorin administered in combination with either irinotecan or oxaliplatin: results from Intergroup Trial N9741. | Cancer 20041115 |
| Phase II study of UFT and oxaliplatin in first-line treatment of advanced colorectal cancer. | British journal of cancer 20041115 |
| Phase II study of S-1 in patients with advanced biliary tract cancer. | British journal of cancer 20041115 |
| Vector targeting makes 5-fluorouracil chemotherapy less toxic and more effective in animal models of epithelial neoplasms. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041115 |
| Prediction of irinotecan pharmacokinetics by use of cytochrome P450 3A4 phenotyping probes. | Journal of the National Cancer Institute 20041103 |
| Complete remission of primary colon cancer in a metastatic patient treated with CPT-11 plus capecitabine. | International journal of colorectal disease 20041101 |
| Antiproliferative effects of ZD0473 (AMD473) in combination with 5-fluorouracil or SN38 in human colorectal cancer cell lines. | Investigational new drugs 20041101 |
| The absence of early diarrhea with atropine premedication during irinotecan therapy in metastatic colorectal patients. | International journal of colorectal disease 20041101 |
| Phase II trial of the antiangiogenic agent IM862 in metastatic renal cell carcinoma. | British journal of cancer 20041101 |
| Treatment of small cell lung cancer. | Critical reviews in oncology/hematology 20041101 |
| Randomized multicenter phase II trial of a biweekly regimen of fluorouracil and leucovorin (LV5FU2), LV5FU2 plus cisplatin, or LV5FU2 plus irinotecan in patients with previously untreated metastatic gastric cancer: a Federation Francophone de Cancerologie Digestive Group Study--FFCD 9803. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20041101 |
| Induction and concurrent chemotherapy with high-dose thoracic conformal radiation therapy in unresectable stage IIIA and IIIB non-small-cell lung cancer: a dose-escalation phase I trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20041101 |
| Phase II study of activated charcoal to prevent irinotecan-induced diarrhea. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20041101 |
| Palliative chemotherapy for advanced gastric cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20041101 |
| A phase I trial of pharmacologic modulation of irinotecan with cyclosporine and phenobarbital. | Clinical pharmacology and therapeutics 20041101 |
| Inhibition of acetylcholinesterase in patients receiving irinotecan (camptothecin-11). | Clinical pharmacology and therapeutics 20041101 |
| Effect of fractionated ifosfamide on the pharmacokinetics of irinotecan in pediatric patients with osteosarcoma. | Journal of pediatric hematology/oncology 20041101 |
| Overview of bevacizumab: a new cancer therapeutic strategy targeting vascular endothelial growth factor. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20041101 |
| Intergroup trial fails to demonstrate a benefit with the addition of irinotecan to bolus 5-fluorouracil/leucovorin in stage III colon cancer. | Clinical colorectal cancer 20041101 |
| [A randomized phase II clinical trial of tailored CPT-11 + TS-1 vs TS-1 in patients with advanced or recurrent gastric carcinoma as the first-line chemotherapy (JFMC31-0301)]. | Gan to kagaku ryoho. Cancer & chemotherapy 20041101 |
| [CPT-11 combined chemotherapy for metastatic gastric cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20041101 |
| [A case of liver metastatic recurrence of gastric cancer effectively treated by combined chemotherapy of CPT-11 and CDDP]. | Gan to kagaku ryoho. Cancer & chemotherapy 20041101 |
| Chemotherapy in metastatic colorectal cancer. | Techniques in coloproctology 20041101 |
| Anti-VEGF antibody bevacizumab (Avastin) with 5FU/LV as third line treatment for colorectal cancer. | Techniques in coloproctology 20041101 |
| Pemetrexed in advanced colorectal cancer. | Oncology (Williston Park, N.Y.) 20041101 |
| Limited potential of hepatic arterial infusion of irinotecan. | Journal of chemotherapy (Florence, Italy) 20041101 |
| Prospective clinical trials using a pharmacogenetic/pharmacogenomic approach. | Journal of chemotherapy (Florence, Italy) 20041101 |
| Uridine diphosphoglucuronosyl transferase and methylenetetrahydrofolate reductase polymorphisms as genomic predictors of toxicity and response to irinotecan-, antifolate- and fluoropyrimidine-based chemotherapy. | Journal of chemotherapy (Florence, Italy) 20041101 |
| Targeting angiogenesis in cancer: clinical development of bevacizumab. | Nature clinical practice. Oncology 20041101 |
| Expression of kinase-defective mutants of c-Src in human metastatic colon cancer cells decreases Bcl-xL and increases oxaliplatin- and Fas-induced apoptosis. | The Journal of biological chemistry 20041029 |
| Accelerated approval of oncology products: a decade of experience. | Journal of the National Cancer Institute 20041020 |
| Elderly patients with fluoropyrimidine and thymidylate synthase inhibitor-resistant advanced colorectal cancer derive similar benefit without excessive toxicity when treated with irinotecan monotherapy. | British journal of cancer 20041018 |
| A randomised phase II multicentre trial of irinotecan (CPT-11) using four different schedules in patients with metastatic colorectal cancer. | British journal of cancer 20041018 |
| Phase II study of a triplet regimen in advanced colorectal cancer using methotrexate, oxaliplatin and 5-fluorouracil. | British journal of cancer 20041018 |
| Phase I dose-escalation trial of irinotecan with continuous infusion 5-FU first line, in metastatic colorectal cancer. | British journal of cancer 20041018 |
| Phase I and pharmacokinetic study of XR11576, an oral topoisomerase I and II inhibitor, administered on days 1-5 of a 3-weekly cycle in patients with advanced solid tumours. | British journal of cancer 20041018 |
| Lack of efficacy of troglitazone at clinically achievable concentrations, with or without 9-cis retinoic acid or cytotoxic agents, for hepatocellular carcinoma cell lines. | British journal of cancer 20041018 |
| Multicentre phase II study of bifractionated CPT-11 with bimonthly leucovorin and 5-fluorouracil in patients with metastatic colorectal cancer pretreated with FOLFOX. | British journal of cancer 20041018 |
| Development of a chemoresistant orthotopic human nonsmall cell lung carcinoma model in nude mice: analyses of tumor heterogenity in relation to the immunohistochemical levels of expression of cyclooxygenase-2, ornithine decarboxylase, lung-related resistance protein, prostaglandin E synthetase, and glutathione-S-transferase-alpha (GST)-alpha, GST-mu, and GST-pi. | Cancer 20041015 |
| Gefitinib enhances the antitumor activity and oral bioavailability of irinotecan in mice. | Cancer research 20041015 |
| Bevacizumab in colorectal cancer. | The New England journal of medicine 20041014 |
| Cetuximab in colon cancer. | The New England journal of medicine 20041007 |
| Cetuximab in colon cancer. | The New England journal of medicine 20041007 |
| Excited-state proton transfer reactions of 10-hydroxycamptothecin. | Journal of the American Chemical Society 20041006 |
| Predicting resistance or response to chemotherapy by proton magnetic resonance spectroscopy in neuroblastoma. | Journal of the National Cancer Institute 20041006 |
| Thymidylate synthase predictive power is overcome by irinotecan combination therapy with S-1 for gastric cancer. | British journal of cancer 20041004 |
| Systemic BCNU enhances the efficacy of local delivery of a topoisomerase I inhibitor against malignant glioma. | Cancer chemotherapy and pharmacology 20041001 |
| Identification of the cytosolic carboxylesterase catalyzing the 5'-deoxy-5-fluorocytidine formation from capecitabine in human liver. | Drug metabolism and disposition: the biological fate of chemicals 20041001 |
| Monoclonal gammopathy of undetermined significance (MGUS) in patients with solid tumors: effects of chemotherapy on the monoclonal protein. | Annals of hematology 20041001 |
| Recent advances in management of small-cell lung cancer. | Cancer treatment reviews 20041001 |
| New approaches to prevent intestinal toxicity of irinotecan-based regimens. | Cancer treatment reviews 20041001 |
| The epidermal growth factor receptor as a target for gastrointestinal cancer therapy. | Current treatment options in oncology 20041001 |
| New options and old dilemmas in the treatment of patients with advanced colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20041001 |
| Heated intra-operative intraperitoneal oxaliplatin plus irinotecan after complete resection of peritoneal carcinomatosis: pharmacokinetics, tissue distribution and tolerance. | Annals of oncology : official journal of the European Society for Medical Oncology 20041001 |
| Rescue surgery for unresectable colorectal liver metastases downstaged by chemotherapy: a model to predict long-term survival. | Annals of surgery 20041001 |
| Phase II study of irinotecan combined with mitomycin-C for advanced or recurrent squamous cell carcinoma of the uterine cervix: the JGOG study. | Gynecologic oncology 20041001 |
| [Advances in palliative and adjuvant chemotherapy of colon cancer]. | Deutsche medizinische Wochenschrift (1946) 20041001 |
| Meta-analysis of new treatment strategies for metastatic colorectal cancer. | Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 20041001 |
| Phase II study of irinotecan (CPT-11) administered every 2 weeks as treatment for patients with colorectal cancer resistant to previous treatment with 5-fluorouracil-based therapies: comparison of two different dose schedules (250 and 200 mg/m2) according to toxicity prognostic factors. | Anti-cancer drugs 20041001 |
| Studies of synergistic and antagonistic combinations of conventional cytotoxic agents with the multiple eicosanoid pathway modulator LY 293111. | Anti-cancer drugs 20041001 |
| A review of oxaliplatin and its clinical use in colorectal cancer. | Expert opinion on pharmacotherapy 20041001 |
| Utility of PET, CT, and EUS to identify pathologic responders in esophageal cancer. | The Annals of thoracic surgery 20041001 |
| Pharmacogenetics of irinotecan toxicity. | Pharmacogenomics 20041001 |
| Camptothecin, over four decades of surprising findings. | Phytochemistry 20041001 |
| Phase I trial of irinotecan, infusional 5-fluorouracil, and leucovorin (FOLFIRI) with erlotinib (OSI-774): early termination due to increased toxicities. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041001 |
| Liposomal irinotecan: formulation development and therapeutic assessment in murine xenograft models of colorectal cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041001 |
| A predictive model of human myelotoxicity using five camptothecin derivatives and the in vitro colony-forming unit granulocyte/macrophage assay. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041001 |
| Integrating the anti-VEGF-A humanized monoclonal antibody bevacizumab with chemotherapy in advanced colorectal cancer. | Clinical colorectal cancer 20041001 |
| [Histoculture drug response assay for solitary fibrous tumor--a case report]. | Gan to kagaku ryoho. Cancer & chemotherapy 20041001 |
| [Irinotecan hydrochloride (CPT-11) for advanced cervical cancer]. | Nihon rinsho. Japanese journal of clinical medicine 20041001 |
| [Chemotherapy using nedaplatin for advanced gynecologic cancers]. | Nihon rinsho. Japanese journal of clinical medicine 20041001 |
| [Treatment of platinum-resistant ovarian cancer]. | Nihon rinsho. Japanese journal of clinical medicine 20041001 |
| [Kampo therapy for side effects of gynecologic carcinomatous chemotherapy]. | Nihon rinsho. Japanese journal of clinical medicine 20041001 |
| Phase I/II study of irinotecan, 5-fluorouracil, and l-leucovorin combination therapy (modified Saltz regimen) in patients with metastatic colorectal cancer. | International journal of clinical oncology 20041001 |
| Doublet regimen of cisplatin plus docetaxel for second-line chemotherapy after prior therapy with cisplatin plus irinotecan for non-small cell lung cancer: a phase II study. | International journal of clinical oncology 20041001 |
| Complete response to irinotecan hydrochloride and nedaplatin in a patient with advanced ovarian clear cell carcinoma. | International journal of clinical oncology 20041001 |
| [Experimental study for a combination chemo-immunotherapy using dendritic cells]. | Gan to kagaku ryoho. Cancer & chemotherapy 20041001 |
| [Successful treatment of liver metastasis and extrahepatic metastasis with hepatic arterial infusion of CDDP, CPT-11, and 5-FU]. | Gan to kagaku ryoho. Cancer & chemotherapy 20041001 |
| [Case report--Complete response of liver metastasis of rectal cancer after combination chemotherapy of CPT-11 + UFT-E]. | Gan to kagaku ryoho. Cancer & chemotherapy 20041001 |
| [CPT-11 hepatic arterial infusion chemotherapy for metastatic liver tumor from gastric cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20041001 |
| [Evaluation of bronchial arterial infusion (BAI) for metastatic lung tumor from colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20041001 |
| [A case of disseminated tumor from cecal cancer with survival for over 5 years after twice surgical resection and systemic chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20041001 |
| [Clinical practice guideline: 2003 update of Standards, Options et Recommendations for first line palliative chemotherapy in patients with metastatic colorectal cancer (summary report)]. | Bulletin du cancer 20041001 |
| Irinotecan combined with bolus 5-fluorouracil and folinic acid for metastatic colorectal cancer: is this really a dangerous treatment? | Journal of chemotherapy (Florence, Italy) 20041001 |
| Cetuximab (Erbitux)--an emerging targeted therapy for epidermal growth factor receptor-expressing tumours. | International journal of clinical practice 20041001 |
| Combination chemotherapy with irinotecan hydrochloride (CPT-11) and mitomycin C in platinum-refractory ovarian cancer. | American journal of clinical oncology 20041001 |
| Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040915 |
| Potentiation of cytotoxicity of topoisomerase i poison by concurrent and sequential treatment with the checkpoint inhibitor UCN-01 involves disparate mechanisms resulting in either p53-independent clonogenic suppression or p53-dependent mitotic catastrophe. | Cancer research 20040915 |
| No topoisomerase I alteration in a neuroblastoma model with in vivo acquired resistance to irinotecan. | British journal of cancer 20040913 |
| Phase I-II study of irinotecan (CPT-11) plus nedaplatin (254-S) with recombinant human granulocyte colony-stimulating factor support in patients with advanced or recurrent cervical cancer. | British journal of cancer 20040913 |
| Adjuvant immunochemotherapy with oral Tegafur/Uracil plus PSK in patients with stage II or III colorectal cancer. | British journal of cancer 20040913 |
| Concise prediction models of anticancer efficacy of 8 drugs using expression data from 12 selected genes. | International journal of cancer 20040910 |
| Prevention of irinotecan-induced diarrhoea by oral carbonaceous adsorbent (Kremezin) in cancer patients. | Oncology reports 20040901 |
| Octreotide LAR resolves severe chemotherapy-induced diarrhoea (CID) and allows continuation of full-dose therapy. | European journal of cancer care 20040901 |
| Clinical overview: adjuvant therapy of gastrointestinal cancer. | Cancer chemotherapy and pharmacology 20040901 |
| Integration of novel agents in the treatment of colorectal cancer. | Cancer chemotherapy and pharmacology 20040901 |
| Recent phase III trials of fluorouracil, irinotecan, and oxaliplatin as chemotherapy for metastatic colorectal cancer. | Cancer chemotherapy and pharmacology 20040901 |
| Pharmacogenomics and stomach cancer. | Pharmacogenomics 20040901 |
| ABCG2 pharmacogenetics: ethnic differences in allele frequency and assessment of influence on irinotecan disposition. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040901 |
| Gefitinib reverses breast cancer resistance protein-mediated drug resistance. | Molecular cancer therapeutics 20040901 |
| Topoisomerase I inhibitors in the treatment of gastrointestinal cancer: from intravenous to oral administration. | Clinical colorectal cancer 20040901 |
| The role of pemetrexed in the treatment of gastrointestinal malignancy. | Clinical colorectal cancer 20040901 |
| Current status of clinical studies for colorectal cancer in Taiwan. | Clinical colorectal cancer 20040901 |
| Roles of infusional high-dose 5-fluorouracil with leucovorin in advanced colorectal cancer. | Clinical colorectal cancer 20040901 |
| Evidence-based update of chemotherapy options for metastatic colorectal cancer. | ANZ journal of surgery 20040901 |
| [Clinical study of irinotecan therapy in patients with fluoropyrimidine-resistant advanced colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040901 |
| [A case report of metastatic pancreatic cancer that responded remarkably to the combination of thalidomide, celecoxib and irinotecan]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040901 |
| [A case of metastatic liver tumor from colorectal carcinoma--continued arterial infusion chemotherapy through a microcatheter located in replaced right hepatic artery]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040901 |
| [A case of 5-FU-resistant recurrent colon cancer treated with low-dose CPT-11/CDDP on an outpatient basis]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040901 |
| Determination and analysis of single nucleotide polymorphisms and haplotype structure of the human carboxylesterase 2 gene. | Pharmacogenetics 20040901 |
| [New drugs for colorectal cancer]. | Praxis 20040901 |
| Biweekly administration of 24-h infusion of irinotecan followed by a 1-h infusion of docetaxel: a phase I study. | Anti-cancer drugs 20040901 |
| Enhanced therapeutic efficacy of a novel liposome-based formulation of SN-38 against human tumor models in SCID mice. | Anti-cancer drugs 20040901 |
| The novel highly lipophilic topoisomerase I inhibitor DB67 is effective in the treatment of liver metastases of murine CT-26 colon carcinoma. | Neoplasia (New York, N.Y.) 20040901 |
| Mayo regimen plus three different second-line chemotherapy regimens in sequential therapy in patients with advanced colorectal cancer (ACRC). | Journal of experimental & clinical cancer research : CR 20040901 |
| The treatment of colorectal carcinoma: standard chemotherapy and beyond. | Clinical advances in hematology & oncology : H&O 20040901 |
| Emerging therapies for metastatic colorectal cancer: focus on EGFR and VEGF inhibition. | Journal of the National Comprehensive Cancer Network : JNCCN 20040901 |
| Capecitabine in combination with mitomycin C in patients with gastrointestinal cancer: results of an extended multicentre phase-I trial. | British journal of cancer 20040831 |
| Phase II study of capecitabine and mitomycin C as first-line treatment in patients with advanced colorectal cancer. | British journal of cancer 20040831 |
| Topoisomerase-I, thymidylate synthase primary tumour expression and clinical efficacy of 5-FU/CPT-11 chemotherapy in advanced colorectal cancer patients. | International journal of cancer 20040820 |
| Multi-institutional phase II trial of irinotecan, cisplatin, and etoposide for sensitive relapsed small-cell lung cancer. | British journal of cancer 20040816 |
| UGT1A1 gene variations and irinotecan treatment in patients with metastatic colorectal cancer. | British journal of cancer 20040816 |
| Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: potential role for breast cancer resistance protein in clinical drug-drug interactions. | Cancer research 20040815 |
| Targeting the epidermal growth factor receptor. | British journal of cancer 20040802 |
| Irinotecan plus gemcitabine vs irinotecan for the second-line treatment of patients with advanced non-small-cell lung cancer pretreated with docetaxel and cisplatin: a multicentre, randomised, phase II study. | British journal of cancer 20040802 |
| UFT/leucovorin and oxaliplatin alternated with UFT/leucovorin and irinotecan in metastatic colorectal cancer. | British journal of cancer 20040802 |
| Temozolomide in paediatric high-grade glioma: a key for combination therapy? | British journal of cancer 20040802 |
| ABCG2 mediates differential resistance to SN-38 (7-ethyl-10-hydroxycamptothecin) and homocamptothecins. | The Journal of pharmacology and experimental therapeutics 20040801 |
| Phase I trial of combined irinotecan and oxaliplatin given every three weeks to patients with metastatic colorectal cancer. | Investigational new drugs 20040801 |
| Effects of oxaliplatin and CPT-11 on cytotoxicity and nucleic acid incorporation of the fluoropyrimidines. | Journal of cancer research and clinical oncology 20040801 |
| Oxaliplatin and irinotecan plus granulocyte-colony stimulating factor as third-line treatment in relapsed or cisplatin-refractory germ-cell tumor patients: a phase II study. | European urology 20040801 |
| Cisplatin enhances the p53-independent apoptosis induced by a topoisomerase I inhibitor (CPT-11) in the lens epithelial tumors in transgenic mice. | Oncology reports 20040801 |
| Usefulness of collagen gel droplet embedded culture drug sensitivity testing in ovarian cancer. | Oncology reports 20040801 |
| UGT1A1*28 polymorphism in ovarian cancer patients. | Oncology reports 20040801 |
| Developments in combination chemotherapy for colorectal cancer. | Expert review of anticancer therapy 20040801 |
| Inducible nuclear factor-kappaB activation contributes to chemotherapy resistance in gastric cancer. | Journal of the American College of Surgeons 20040801 |
| Combination of irinotecan (CPT-11) plus oxaliplatin (L-OHP) as first-line treatment in locally advanced or metastatic gastric cancer: a multicentre phase II trial. | Annals of oncology : official journal of the European Society for Medical Oncology 20040801 |
| Neomycin as secondary prophylaxis for irinotecan-induced diarrhea. | Annals of oncology : official journal of the European Society for Medical Oncology 20040801 |
| Rapid detection of UGT1A1 gene polymorphisms by newly developed Invader assay. | Clinical chemistry 20040801 |
| Extent of hepatic resection does not correlate with toxicity following adjuvant chemotherapy. | Journal of surgical oncology 20040801 |
| A randomized trial comparing defined-duration with continuous irinotecan until disease progression in fluoropyrimidine and thymidylate synthase inhibitor-resistant advanced colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040801 |
| Influence of genetic variants in UGT1A1 and UGT1A9 on the in vivo glucuronidation of SN-38. | Journal of clinical pharmacology 20040801 |
| Cisplatin and irinotecan in squamous cell carcinoma of the cervix: a phase II study of the Gynecologic Oncology Group. | Gynecologic oncology 20040801 |
| Relevance of different UGT1A1 polymorphisms in irinotecan-induced toxicity: a molecular and clinical study of 75 patients. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040801 |
| Characterization of inhibitors of specific carboxylesterases: development of carboxylesterase inhibitors for translational application. | Molecular cancer therapeutics 20040801 |
| Treatment issues in pediatric gastric adenocarcinoma. | Journal of pediatric surgery 20040801 |
| [A case of hepatic metastasis from colon cancer successfully treated with 5-FU, levofolinate (l-LV) and low-dose CPT-11]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040801 |
| [A successfully resected case of colorectal cancer with multiple liver metastases treated with systemic chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040801 |
| Interstitial lung disease in patients with non-small-cell lung cancer: causes, mechanisms and management. | British journal of cancer 20040801 |
| Treatment of non-small-cell lung cancer: a perspective on the recent advances and the experience with gefitinib. | British journal of cancer 20040801 |
| Interstitial lung disease associated with drug therapy. | British journal of cancer 20040801 |
| Understanding the mechanisms of drug-associated interstitial lung disease. | British journal of cancer 20040801 |
| [Five cytostatic substances in animal studies for prevention and treatment of experimentally induced peritoneal carcinomatosis]. | Zentralblatt fur Chirurgie 20040801 |
| Phase II study of irinotecan, 5-fluorouracil, and leucovorin in relapsed or metastatic colorectal cancer as first-line therapy. | Cancer research and treatment : official journal of Korean Cancer Association 20040801 |
| The price tag on progress--chemotherapy for colorectal cancer. | The New England journal of medicine 20040722 |
| Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. | The New England journal of medicine 20040722 |
| New treatment options for colorectal cancer. | The New England journal of medicine 20040722 |
| A multivariate analysis of genomic polymorphisms: prediction of clinical outcome to 5-FU/oxaliplatin combination chemotherapy in refractory colorectal cancer. | British journal of cancer 20040719 |
| Adjusting for differential proportions of second-line treatment in cancer clinical trials. Part II: an application in a clinical trial of unresectable non-small-cell lung cancer. | Statistics in medicine 20040715 |
| Randomized phase II study of two irinotecan schedules for patients with metastatic breast cancer refractory to an anthracycline, a taxane, or both. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040715 |
| Recommended guidelines for the treatment of cancer treatment-induced diarrhea. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040715 |
| Increased expression of metallothionein is associated with irinotecan resistance in gastric cancer. | Cancer research 20040715 |
| Phase I and pharmacokinetic (PK) study of MAG-CPT (PNU 166148): a polymeric derivative of camptothecin (CPT). | British journal of cancer 20040705 |
| Combination chemotherapy with epirubicin, docetaxel and cisplatin (EDP) in metastatic or recurrent, unresectable gastric cancer. | British journal of cancer 20040705 |
| Saccharic acid 1.4-lactone protects against CPT-11-induced mucosa damage in rats. | Journal of cancer research and clinical oncology 20040701 |
| Treatment options for small cell lung cancer. | Current oncology reports 20040701 |
| The schedule-dependent enhanced cytotoxic activity of 7-ethyl-10-hydroxy-camptothecin (SN-38) in combination with Gefitinib (Iressa, ZD1839). | Biochemical pharmacology 20040701 |
| Hepatic arterial chemotherapy for colorectal cancer liver metastases: a review of advances in 2003. | Current opinion in oncology 20040701 |
| A phase I study and pharmacokinetics of irinotecan (CPT-11) and paclitaxel in patients with advanced non-small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20040701 |
| Phase I study of docetaxel and irinotecan in patients with advanced non-small-cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20040701 |
| Irinotecan and docetaxel as first line chemotherapy in patients with stage IIIB/IV non-small cell lung cancer--experience from a prematurely closed phase II study. | Lung cancer (Amsterdam, Netherlands) 20040701 |
| Predictive factors of survival in patients with advanced colorectal cancer: an individual data analysis of 602 patients included in irinotecan phase III trials. | Annals of oncology : official journal of the European Society for Medical Oncology 20040701 |
| Dose-finding study of weekly 24-h continuous infusion of 5-fluorouracil associated with alternating oxaliplatin or irinotecan in advanced colorectal cancer patients. | Annals of oncology : official journal of the European Society for Medical Oncology 20040701 |
| Irinotecan chemotherapy associated with transient dysarthria and aphasia. | Annals of oncology : official journal of the European Society for Medical Oncology 20040701 |
| Combined topoisomerase I inhibition for the treatment of metastatic colon cancer. | Anti-cancer drugs 20040701 |
| The in vitro effects of CRE-decoy oligonucleotides in combination with conventional chemotherapy in colorectal cancer cell lines. | European journal of biochemistry 20040701 |
| Cetuximab: an IgG(1) monoclonal antibody for the treatment of epidermal growth factor receptor-expressing tumours. | Expert opinion on pharmacotherapy 20040701 |
| Enhanced 7-ethyl-10-hydroxycamptothecin (SN-38) lethality by methylselenocysteine is associated with Chk2 phosphorylation at threonine-68 and down-regulation of Cdc6 expression. | Molecular pharmacology 20040701 |
| [A case of TS-1 resistant recurrent gastric cancer responding to TS-1 +CPT-11 combination therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040701 |
| Chemotherapy in gastric cancer: a brief chronicle with emphasis on recent developments. | The Israel Medical Association journal : IMAJ 20040701 |
| Retrospective study of resection of pulmonary metastases in patients with advanced colorectal cancer: the development of a preoperative chemotherapy strategy. | Clinical colorectal cancer 20040701 |
| [Evidence-based practice guideline for unresectable advanced lung cancer in 2003]. | Nihon Geka Gakkai zasshi 20040701 |
| Current paradigms in first-line treatment of non-small-cell lung cancer. | Oncology (Williston Park, N.Y.) 20040701 |
| Clinical trials for malignant lymphoma in Japan. | Japanese journal of clinical oncology 20040701 |
| Circadian rhythm of irinotecan tolerability in mice. | Chronobiology international 20040701 |
| Flat-fixed dosing of irinotecan: influence on pharmacokinetic and pharmacodynamic variability. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040615 |
| Cytotoxic chemotherapy in advanced non-small cell lung cancer: a review of standard treatment paradigms. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040615 |
| A phase I study with MAG-camptothecin intravenously administered weekly for 3 weeks in a 4-week cycle in adult patients with solid tumours. | British journal of cancer 20040614 |
| Mechanisms of camptothecin resistance by human topoisomerase I mutations. | Journal of molecular biology 20040611 |
| Two new drugs for colon cancer. | The Medical letter on drugs and therapeutics 20040607 |
| Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. | The New England journal of medicine 20040603 |
| Phase I and pharmacokinetic study of the farnesyltransferase inhibitor R115777 in combination with irinotecan in patients with advanced cancer. | Cancer chemotherapy and pharmacology 20040601 |
| Neoadjuvant treatment of unresectable liver disease with irinotecan and 5-fluorouracil plus folinic acid in colorectal cancer patients. | Annals of oncology : official journal of the European Society for Medical Oncology 20040601 |
| Discovery of novel selective inhibitors of human intestinal carboxylesterase for the amelioration of irinotecan-induced diarrhea: synthesis, quantitative structure-activity relationship analysis, and biological activity. | Molecular pharmacology 20040601 |
| An immediate hemolytic reaction induced by repeated administration of oxaliplatin. | Transfusion 20040601 |
| Preoperative induction of CPT-11 and cisplatin chemotherapy followed by chemoradiotherapy in patients with locoregional carcinoma of the esophagus or gastroesophageal junction. | Cancer 20040601 |
| Phase I study of the combination of oxaliplatin, irinotecan and continuous infusion 5-fluorouracil in digestive tumors. | Anti-cancer drugs 20040601 |
| Prospective multicenter phase II study of irinotecan as third-line therapy in metastatic colorectal cancer and progression after bolus and infusional 5-fluorouracil. | Anti-cancer drugs 20040601 |
| Oxaliplatin plus irinotecan and FU-FOL combination and pharmacokinetic analysis in advanced colorectal cancer patients. | American journal of clinical oncology 20040601 |
| 'Irinogenetics' and UGT1A: from genotypes to haplotypes. | Clinical pharmacology and therapeutics 20040601 |
| UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer. | Clinical pharmacology and therapeutics 20040601 |
| A novel mouse model of rectal cancer established by orthotopic implantation of colon cancer cells. | Cancer science 20040601 |
| In vitro conversion of irinotecan to SN-38 in human plasma. | Cancer science 20040601 |
| Dependence of chemotherapy response on p53 mutation status in a panel of human cancer lines maintained in nude mice. | Cancer science 20040601 |
| [Management of chemotherapy induced diarrhea]. | Zeitschrift fur Gastroenterologie 20040601 |
| Drug sensitivity-related benefit of systematic lymphadenectomy during cytoreductive surgery in optimally debulked stages IIIc and IV ovarian cancer. | Gynecologic oncology 20040601 |
| Current approaches to first-line treatment of advanced colorectal cancer. | Clinical colorectal cancer 20040601 |
| Current status of second-line therapy for metastatic colorectal cancer. | Clinical colorectal cancer 20040601 |
| An overview of adjuvant systemic chemotherapy for colon cancer. | Clinical colorectal cancer 20040601 |
| Oxaliplatin plus oral fluoropyrimidines in colorectal cancer. | Clinical colorectal cancer 20040601 |
| Application of pharmacogenomics in the individualization of chemotherapy for gastrointestinal malignancies. | Clinical colorectal cancer 20040601 |
| Potential interactions between irinotecan and rifampin in a patient with small-cell lung cancer. | International journal of clinical oncology 20040601 |
| [Retrospective study of irinotecan plus fluorouracil and l-leucovorin chemotherapy for advanced and metastatic colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040601 |
| [Successful downstaging by a low-dose, fractional administration of irinotecan hydrochloride (CPT-11) in combination with cisplatin in peritoneal lavage cytology positive, 5-fluorouracil refractory advanced gastric cancer patients]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040601 |
| Pharmacokinetic modulation of irinotecan metabolites by sulphobromophthalein in rats. | The Journal of pharmacy and pharmacology 20040601 |
| Phase I dose escalation study of carboplatin to a fixed dose of irinotecan as first-line treatment of small cell lung cancer. | Onkologie 20040601 |
| [New therapy options in colorectal carcinoma]. | Therapeutische Umschau. Revue therapeutique 20040601 |
| Topoisomerase I inhibitors in small-cell lung cancer. The Japanese experience. | Oncology (Williston Park, N.Y.) 20040601 |
| Irinotecan in advanced lung cancer: focus on North American trials. | Oncology (Williston Park, N.Y.) 20040601 |
| Topoisomerase I inhibitors in the combined-modality therapy of lung cancer. | Oncology (Williston Park, N.Y.) 20040601 |
| Pharmacokinetic interactions of drugs with St John's wort. | Journal of psychopharmacology (Oxford, England) 20040601 |
| Activity of irinotecan, cisplatin and dacarbazine (CPD) combination in previously treated patients with advanced colorectal carcinoma. | Experimental oncology 20040601 |
| A randomized phase II clinical trial of tailored CPT-11 + S-1 vs S-1 in patients with advanced or recurrent gastric carcinoma as the first line chemotherapy. | Japanese journal of clinical oncology 20040601 |
| Pegylated liposomal doxorubicin in combination with mitomycin C, infusional 5-fluorouracil and sodium folinic acid. A phase-I-study in patients with upper gastrointestinal cancer. | British journal of cancer 20040517 |
| Oxaliplatin- or irinotecan-based chemotherapy for metastatic colorectal cancer in the elderly. | British journal of cancer 20040517 |
| Chemoresistance: impact of nuclear factor (NF)-kappaB inhibition by small interfering RNA. Commentary re J. Guo et al., Enhanced chemosensitivity to irinotecan by RNA interference-mediated down-regulation of the NF-kappaB p65 subunit. Clin Cancer Res 2004;10:3333-3341. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040515 |
| Enhanced chemosensitivity to irinotecan by RNA interference-mediated down-regulation of the nuclear factor-kappaB p65 subunit. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040515 |
| ABCG2 overexpression in colon cancer cells resistant to SN38 and in irinotecan-treated metastases. | International journal of cancer 20040510 |
| Small-cell carcinoma of the gastrointestinal tract: a retrospective study of 64 cases. | British journal of cancer 20040504 |
| A novel biweekly multidrug regimen of gemcitabine, oxaliplatin, 5-fluorouracil (5-FU), and folinic acid (FA) in pretreated patients with advanced colorectal carcinoma. | British journal of cancer 20040504 |
| Modeling antitumor activity by using a non-linear mixed-effects model. | Mathematical biosciences 20040501 |
| Indirect determination of the irinotecan metabolite 7-ethyl-10-O-glucuronyl-camptothecin in human samples. | Analytical biochemistry 20040501 |
| Hydrolysis of irinotecan and its oxidative metabolites, 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino] carbonyloxycamptothecin and 7-ethyl-10-[4-(1-piperidino)-1-amino]-carbonyloxycamptothecin, by human carboxylesterases CES1A1, CES2, and a newly expressed carboxylesterase isoenzyme, CES3. | Drug metabolism and disposition: the biological fate of chemicals 20040501 |
| A flow cytometric assay for simultaneous assessment of drug efflux, proliferation, and apoptosis. | Cytometry. Part B, Clinical cytometry 20040501 |
| Irinotecan-induced interstitial pneumonia. | The Lancet. Oncology 20040501 |
| In vivo treatment with CPT-11 leads to differentiation of neuroblastoma xenografts and topoisomerase I alterations. | Cancer research 20040501 |
| The expressions of p21 and pRB may be good indicators for the sensitivity of esophageal squamous cell cancers to CPT-11: Cell proliferation activity correlates with the effect of CPT-11. | Cancer science 20040501 |
| [Chemotherapy for small cell lung cancer]. | Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20040501 |
| [A case of gastric metastasis of small cell cancer of the lung, regression of the gastric lesion after chemotherapy]. | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20040501 |
| [Chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040501 |
| [A case of colon carcinoma with unresectable multiple liver metastases responding to various combined chemotherapies centering on hepatic arterial infusion therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040501 |
| Reactivation of hepatitis C virus after chemotherapy for colon cancer. | Clinical oncology (Royal College of Radiologists (Great Britain)) 20040501 |
| Pancreatic carcinoma with brain metastases: case report and literature review. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20040501 |
| Phase II trial of capecitabine/irinotecan and capecitabine/oxaliplatin in advanced gastrointestinal cancers. | Clinical colorectal cancer 20040501 |
| Progress in the development of novel treatments for colorectal cancer. | Oncology (Williston Park, N.Y.) 20040501 |
| Current strategies in previously untreated advanced colorectal cancer. | Oncology (Williston Park, N.Y.) 20040501 |
| Current status of adjuvant therapy for colorectal cancer. | Oncology (Williston Park, N.Y.) 20040501 |
| A preliminary study of preoperative chemotherapy combining irinotecan and cisplatin in patients with gastric cancer with unresectable para-aortic lymph node metastases. | Japanese journal of clinical oncology 20040501 |
| [Homocamptothecins--novel promising anticancer drugs as inhibitors of topoisomerase I]. | Yao xue xue bao = Acta pharmaceutica Sinica 20040501 |
| Irinotecan plus raltitrexed as first-line treatment in advanced colorectal cancer: a phase II study. | British journal of cancer 20040419 |
| Phase I and pharmacokinetic study of irinotecan in combination with R115777, a farnesyl protein transferase inhibitor. | British journal of cancer 20040419 |
| A phase II study of gemcitabine and cisplatin in chemotherapy-naive, unresectable gall bladder cancer. | British journal of cancer 20040419 |
| Irinotecan pharmacogenetics: is it time to intervene? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040415 |
| Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040415 |
| New systemic frontline treatment for metastatic colorectal carcinoma. | Cancer 20040415 |
| Relationship of baseline serum bilirubin to efficacy and toxicity of single-agent irinotecan in patients with metastatic colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040415 |
| Oral RDP58 allows CPT-11 dose intensification for enhanced tumor response by decreasing gastrointestinal toxicity. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040415 |
| Efficient and chemoselective N-acylation of 10-amino-7-ethyl camptothecin with poly(ethylene glycol). | Bioorganic & medicinal chemistry letters 20040405 |
| A novel combination of cisplatin, irinotecan, and capecitabine in patients with advanced cancer. | Investigational new drugs 20040401 |
| Chemoembolization of rat liver metastasis with irinotecan and quantification of tumor cell reduction. | Journal of cancer research and clinical oncology 20040401 |
| Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040401 |
| Weekly administration of irinotecan (CPT-11) plus cisplatin for refractory or relapsed small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20040401 |
| Is overall survival a realistic primary end point in advanced colorectal cancer studies? A critical assessment based on four clinical trials comparing fluorouracil plus leucovorin with the same treatment combined either with oxaliplatin or with CPT-11. | Annals of oncology : official journal of the European Society for Medical Oncology 20040401 |
| Phase I/II trial of irinotecan plus high-dose 5-fluorouracil (TTD regimen) as first-line chemotherapy in advanced colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20040401 |
| Survival of patients with advanced colorectal cancer improves with the availability of fluorouracil-leucovorin, irinotecan, and oxaliplatin in the course of treatment. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040401 |
| Down-regulation of thymidylate synthase expression and its steady-state mRNA by oxaliplatin in colon cancer cells. | Anti-cancer drugs 20040401 |
| Imatinib mesylate is a potent inhibitor of the ABCG2 (BCRP) transporter and reverses resistance to topotecan and SN-38 in vitro. | Cancer research 20040401 |
| Selective modulation of the therapeutic efficacy of anticancer drugs by selenium containing compounds against human tumor xenografts. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040401 |
| Phase I study of CPT-11 and bolus 5-FU/ l-leucovorin in patients with metastatic colorectal cancer. | International journal of clinical oncology 20040401 |
| [Screening of DNA topoisomerase inhibitors]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040401 |
| [Screening for inhibitors of tumor invasion into basement membranes]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040401 |
| [Structure-activity relationship analysis]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040401 |
| [Report of two cases with pleural effusion and ascites that responded dramatically to the combination of thalidomide, celecoxib, irinotecan, and CDDP infused in thoracic and abdominal cavities]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040401 |
| Phase 2 trial of BCNU plus irinotecan in adults with malignant glioma. | Neuro-oncology 20040401 |
| Phase 1 trial of irinotecan plus BCNU in patients with progressive or recurrent malignant glioma. | Neuro-oncology 20040401 |
| Phase I study of the combination of irinotecan hydrochloride, carboplatin, and dexamethasone for the treatment of relapsed or refractory malignant lymphoma. | International journal of hematology 20040401 |
| Pharmacogenetics of neoplastic diseases: new trends. | Pharmacological research 20040401 |
| Transport of SN-38 by the wild type of human ABC transporter ABCG2 and its inhibition by quercetin, a natural flavonoid. | Journal of experimental therapeutics & oncology 20040401 |
| Phase I/II study of cisplatin combined with weekly paclitaxel in patients with advanced non-small-cell lung cancer. | British journal of cancer 20040322 |
| Oral capecitabine vs intravenous 5-fluorouracil and leucovorin: integrated efficacy data and novel analyses from two large, randomised, phase III trials. | British journal of cancer 20040322 |
| Comparative pharmacokinetics of weekly and every-three-weeks docetaxel. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040315 |
| Characterization of p53 wild-type and null isogenic colorectal cancer cell lines resistant to 5-fluorouracil, oxaliplatin, and irinotecan. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040315 |
| Preoperative concurrent chemoradiotherapy with cisplatin and docetaxel in patients with locally advanced non-small-cell lung cancer. | British journal of cancer 20040308 |
| Adjuvant immunochemotherapy with oral Tegafur/Uracil plus PSK in patients with stage II or III colorectal cancer: a randomised controlled study. | British journal of cancer 20040308 |
| Enhanced sensitivity to irinotecan by Cdk1 inhibition in the p53-deficient HT29 human colon cancer cell line. | Oncogene 20040304 |
| Thrombospondin-1 plus irinotecan: a novel antiangiogenic-chemotherapeutic combination that inhibits the growth of advanced human colon tumor xenografts in mice. | Cancer chemotherapy and pharmacology 20040301 |
| Phase I trial of UFT/leucovorin and irinotecan in patients with advanced cancer. | European journal of cancer (Oxford, England : 1990) 20040301 |
| Emerging role of epidermal growth factor receptor inhibition in therapy for advanced malignancy: focus on NSCLC. | International journal of radiation oncology, biology, physics 20040301 |
| Involvement of organic anion transporting polypeptides in the transport of troglitazone sulfate: implications for understanding troglitazone hepatotoxicity. | Drug metabolism and disposition: the biological fate of chemicals 20040301 |
| Randomized phase II trial of gemcitabine plus irinotecan or docetaxel in stage IIIB or stage IV NSCLC. | Annals of oncology : official journal of the European Society for Medical Oncology 20040301 |
| Enzyme-catalyzed activation of anticancer prodrugs. | Pharmacological reviews 20040301 |
| Quantification of tumor tissue populations by multispectral analysis. | Magnetic resonance in medicine 20040301 |
| Gilbert's syndrome and fluorouracil toxicity in colorectal cancer patients: which correlation? | Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20040301 |
| Camptothecins in clinical development. | Expert opinion on investigational drugs 20040301 |
| A phase I and pharmacokinetic study of irinotecan given as a 7-day continuous infusion in metastatic colorectal cancer patients pretreated with 5-fluorouracil or raltitrexed. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040301 |
| Phase I dose-finding study of biweekly irinotecan in combination with fixed doses of 5-fluorouracil/leucovorin, gemcitabine and cisplatin (G-FLIP) in patients with advanced pancreatic cancer or other solid tumors. | Anti-cancer drugs 20040301 |
| Sequence-dependent effect of a cyclooxygenase-2 inhibitor on topoisomerase I inhibitor and 5-fluorouracil-induced cytotoxicity of colon cancer cells. | Anti-cancer drugs 20040301 |
| [Two cases of metastatic or recurrent rectal cancer responding to combined chemotherapy of low-dose CPT-11 and 5'-DFUR as second-line chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040301 |
| [A case report of colon cancer with liver and lung metastases responding to combination chemotherapy with l-LV, 5-fluorouracil and CPT-11]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040301 |
| [A case of highly advanced ascending colon cancer with multiple bone and liver metastases and pleuritis carcinomatosa treated with pharmacokinetic modulating chemotherapy and low-dose CPT-11]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040301 |
| Drug interactions with St. John's Wort (Hypericum perforatum): a review of the clinical evidence. | International journal of clinical pharmacology and therapeutics 20040301 |
| Chemotherapy-induced lung disease. | Clinics in chest medicine 20040301 |
| Chemotherapy of small cell lung cancer: state of the art. | Current opinion in oncology 20040301 |
| Systemic treatment of oesophageal cancer. | European journal of gastroenterology & hepatology 20040301 |
| Systemic treatment of gastric cancer. | European journal of gastroenterology & hepatology 20040301 |
| Systemic treatment of advanced colorectal carcinoma. | European journal of gastroenterology & hepatology 20040301 |
| [Resection of liver metastasis of colorectal origin following chemotherapy with irinotecan]. | Annales de chirurgie 20040301 |
| [Surgery of liver metastasis from colorectal cancer following irinotecan and 5FU-folinic acid]. | Annales de chirurgie 20040301 |
| Predictive molecular markers: has the time come for routine use in lung cancer? | Journal of the National Comprehensive Cancer Network : JNCCN 20040301 |
| Synthesis, characterization, and preliminary in vivo tests of new poly(ethylene glycol) conjugates of the antitumor agent 10-amino-7-ethylcamptothecin. | Journal of medicinal chemistry 20040226 |
| Molecular modeling of CPT-11 metabolism by carboxylesterases (CEs): use of pnb CE as a model. | Biochemistry 20040224 |
| Pheophorbide a is a specific probe for ABCG2 function and inhibition. | Cancer research 20040215 |
| p53 disruption profoundly alters the response of human glioblastoma cells to DNA topoisomerase I inhibition. | Oncogene 20040212 |
| Development and characterization of a novel liposome-based formulation of SN-38. | International journal of pharmaceutics 20040211 |
| Gefitinib ('Iressa', ZD1839) and new epidermal growth factor receptor inhibitors. | British journal of cancer 20040209 |
| Temozolomide in combination with irinotecan for treatment of recurrent malignant glioma. | American journal of clinical oncology 20040201 |
| First-line hepatic infusion of pirarubicin in patients with isolated liver metastases: is it really promising? | Annals of oncology : official journal of the European Society for Medical Oncology 20040201 |
| Predictive pharmacokinetic-pharmacodynamic modeling of tumor growth kinetics in xenograft models after administration of anticancer agents. | Cancer research 20040201 |
| Cullin 3 promotes proteasomal degradation of the topoisomerase I-DNA covalent complex. | Cancer research 20040201 |
| Phase I trial of temozolomide and protracted irinotecan in pediatric patients with refractory solid tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040201 |
| Therapeutic synergy between irinotecan and 5-fluorouracil against human tumor xenografts. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040201 |
| Camptothecin and taxol: historic achievements in natural products research. | Journal of natural products 20040201 |
| Focus on gastric cancer. | Cancer cell 20040201 |
| Unresectable alpha fetoprotein-producing gastric cancer successfully treated with irinotecan and mitomycin C after S-1 failure. | Internal medicine (Tokyo, Japan) 20040201 |
| Innovative drugs and strategies in the treatment of upper gastrointestinal tract carcinomas. | Onkologie 20040201 |
| A prospective blinded study of the predictive value of an extreme drug resistance assay in patients receiving CPT-11 for recurrent glioma. | Journal of neuro-oncology 20040201 |
| The modulated oral fluoropyrimidine prodrug S-1, and its use in gastrointestinal cancer and other solid tumors. | Anti-cancer drugs 20040201 |
| New developments in the treatment of esophageal cancer. | Clinical advances in hematology & oncology : H&O 20040201 |
| [Colorectal cancers: management of metastatic cancers]. | La Revue du praticien 20040131 |
| UFT/leucovorin and oxaliplatin alternated with UFT/leucovorin and irinotecan in metastatic colorectal cancer. | British journal of cancer 20040126 |
| Phase I trial of concurrent chemoradiotherapy with docetaxel, cisplatin and 5-fluorouracil (TPF) in patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN). | British journal of cancer 20040126 |
| Improved survival in patients with peritoneal metastases from colorectal cancer: a preliminary study. | British journal of cancer 20040126 |
| Biliary excretion of irinotecan and its metabolites. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20040123 |
| Synergistic interaction between the EGFR tyrosine kinase inhibitor gefitinib ('Iressa') and the DNA topoisomerase I inhibitor CPT-11 (irinotecan) in human colorectal cancer cells. | International journal of cancer 20040120 |
| FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040115 |
| Randomized multicenter Phase II trial of two different schedules of irinotecan combined with capecitabine as first-line treatment in metastatic colorectal carcinoma. | Cancer 20040115 |
| Angiogenesis inhibitors in clinical development; where are we now and where are we going? | British journal of cancer 20040112 |
| Cancer pharmacogenetics. | British journal of cancer 20040112 |
| Phase II study of viscum fraxini-2 in patients with advanced hepatocellular carcinoma. | British journal of cancer 20040112 |
| Definitive chemoradiation in patients with inoperable oesophageal carcinoma. | British journal of cancer 20040112 |
| Randomised phase II study of docetaxel/cisplatin vs docetaxel/irinotecan in advanced non-small-cell lung cancer: a West Japan Thoracic Oncology Group Study (WJTOG9803). | British journal of cancer 20040112 |
| Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361. | Journal of the National Cancer Institute 20040107 |
| Biweekly docetaxel-irinotecan with filgrastim support in pretreated breast and non-small-cell lung cancer patients. A phase I study. | Cancer chemotherapy and pharmacology 20040101 |
| A phase II study of intravenous exatecan mesylate (DX-8951f) administered daily for 5 days every 3 weeks to patients with advanced ovarian, tubal or peritoneal cancer resistant to platinum, taxane and topotecan. | Cancer chemotherapy and pharmacology 20040101 |
| Reversal of breast cancer resistance protein (BCRP/ABCG2)-mediated drug resistance by novobiocin, a coumermycin antibiotic. | International journal of cancer 20040101 |
| CD44 variant 6 expression predicts response to treatment in advanced colorectal cancer. | Oncology reports 20040101 |
| Enzyme-prodrug systems: carboxylesterase/CPT-11. | Methods in molecular medicine 20040101 |
| A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040101 |
| Glucuronidation as a mechanism of intrinsic drug resistance in colon cancer cells: contribution of drug transport proteins. | Biochemical pharmacology 20040101 |
| Continuous infusion of hepatic arterial irinotecan in pretreated patients with colorectal cancer metastatic to the liver. | Annals of oncology : official journal of the European Society for Medical Oncology 20040101 |
| Phase II study of irinotecan and 5-fluorouracil/leucovorin in patients with primary refractory or relapsed advanced oesophageal and gastric carcinoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20040101 |
| Effect of re-treatment with gefitinib ('Iressa', ZD1839) after acquisition of resistance. | Annals of oncology : official journal of the European Society for Medical Oncology 20040101 |
| Serum levels of KL-6 for predicting the occurrence of radiation pneumonitis after stereotactic radiotherapy for lung tumors. | Chest 20040101 |
| First-line treatment strategies to improve survival in patients with advanced colorectal cancer. | Drugs 20040101 |
| Cetuximab: in the treatment of metastatic colorectal cancer. | Drugs 20040101 |
| Combretastatin A-4 phosphate enhances CPT-11 activity independently of the administration sequence. | European journal of cancer (Oxford, England : 1990) 20040101 |
| Anticancer drug response and expression of molecular markers in early-passage xenotransplanted colon carcinomas. | European journal of cancer (Oxford, England : 1990) 20040101 |
| Camptothecin analogs (irinotecan or topotecan) plus high-dose cyclophosphamide as preparative regimens for antibody-based immunotherapy in resistant neuroblastoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040101 |
| [Principles of postoperative therapy in rectal carcinoma]. | Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 20040101 |
| Biological characterization of MLN944: a potent DNA binding agent. | Molecular cancer therapeutics 20040101 |
| Phase 2 trial of carboplatin, paclitaxel, and irinotecan in ovarian, fallopian tube, and primary peritoneal cancers. | Gynecologic oncology 20040101 |
| FDA drug approval summaries: oxaliplatin. | The oncologist 20040101 |
| Phase 2 study of weekly irinotecan in adults with recurrent malignant glioma: final report of NABTT 97-11. | Neuro-oncology 20040101 |
| Phase 1 trial of irinotecan (CPT-11) in patients with recurrent malignant glioma: a North American Brain Tumor Consortium study. | Neuro-oncology 20040101 |
| Management of colorectal cancer in elderly patients: focus on the cost of chemotherapy. | Drugs & aging 20040101 |
| [Colon cancer: what is new in 2004?]. | Bulletin du cancer 20040101 |
| Pilot study of low-dose, divided maximum tolerated dose of CPT-11 in 21 consecutive patients with metastatic colorectal or gastric cancer. | Surgery today 20040101 |
| Treatment of colorectal cancer metastasis: the role of chemotherapy. | Cancer metastasis reviews 20040101 |
| Weekly irinotecan in patients with metastatic gastric cancer failing cisplatin-based chemotherapy. | Japanese journal of clinical oncology 20040101 |
| The role of new agents in the treatment of colorectal cancer. | Oncology 20040101 |
| Response to chemotherapy (irinotecan plus 5-fluorouracil) in colorectal carcinoma can be predicted by tumour DNA content. | Oncology 20040101 |
| [Combined treatment of esophageal cancer: a review]. | Medicina (Kaunas, Lithuania) 20040101 |
| [The guidelines for diagnostics and treatment of cervical cancer]. | Medicina (Kaunas, Lithuania) 20040101 |
| Membrane transport of camptothecin: facilitation by human P-glycoprotein (ABCB1) and multidrug resistance protein 2 (ABCC2). | BMC medicine 20040101 |
| Dose escalation study of paclitaxel in combination with fixed-dose irinotecan in patients with advanced non-small cell lung cancer (JCOG 9807). | Oncology 20040101 |
| Efficacy of treatment with irinotecan and oxaliplatin combination in FU-resistant metastatic colorectal cancer patients. | Oncology 20040101 |
| Effect of human noxa on irinotecan-induced apoptosis in human gastric carcinoma cell lines. | Hepato-gastroenterology 20040101 |
| Cancer patients submitted to innovative chemotherapeutic agents of intermediate emetogenic potential: antiemetic prescriptions and incidence of emesis. | Tumori 20040101 |
| 5-Fluorouracil: identification of novel downstream mediators of tumour response. | Anticancer research 20040101 |
| A novel approach in the treatment of neuroendocrine gastrointestinal tumors: additive antiproliferative effects of interferon-gamma and meta-iodobenzylguanidine. | BMC cancer 20040101 |
| Cellular parameters predictive of the clinical response of colorectal cancers to irinotecan. A preliminary study. | Anticancer research 20040101 |
| New chemotherapeutic advances in pancreatic, colorectal, and gastric cancers. | The oncologist 20040101 |
| Targeted therapy of colorectal cancer: clinical experience with bevacizumab. | The oncologist 20040101 |
| [Capecitabine and irinotecan]. | I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.] 20040101 |
| A multicenter phase II study of the combination of irinotecan and gemcitabine in previously treated patients with small-cell lung cancer. | Oncology 20040101 |
| Effect of selenite combined with chemotherapeutic agents on the proliferation of human carcinoma cell lines. | Biological trace element research 20040101 |
| Phase II study of neoadjuvant 5-FU + leucovorin + CPT-11 in patients with resectable liver metastases from colorectal adenocarcinoma. | BMC cancer 20040101 |
| Efficacy of quality criteria to identify potentially harmful information: a cross-sectional survey of complementary and alternative medicine web sites. | Journal of medical Internet research 20040101 |
| Efficacy of cancer chemotherapy in relation to the pretreatment number of lymphocytes in patients with metastatic solid tumors. | The International journal of biological markers 20040101 |
| Phase I/II study of first-line irinotecan combined with 5-fluorouracil and folinic acid Mayo Clinic schedule in patients with advanced colorectal cancer. | BMC cancer 20040101 |
| Irinotecan plus folinic acid/continuous 5-fluorouracil as simplified bimonthly FOLFIRI regimen for first-line therapy of metastatic colorectal cancer. | BMC cancer 20040101 |
| Oxaliplatin hepatic arterial infusion chemotherapy for hepatic metastases from colorectal cancer: a phase I-II clinical study. | Anticancer research 20040101 |
| [Liver resection after downstaging with neoadjuvant chemotherapy for 'unresectable' colorectal metastases]. | Chirurgia italiana 20040101 |
| [Present-day potential of medication for disseminated cervical carcinoma]. | Voprosy onkologii 20040101 |
| New targets for therapy in breast cancer: small molecule tyrosine kinase inhibitors. | Breast cancer research : BCR 20040101 |
| First-line chemotherapy with irinotecan plus capecitabine for advanced colorectal cancer. | Oncology 20040101 |
| A phase II study of irinotecan alternated with a weekly schedule of oxaliplatin, high-dose leucovorin and 48-hour infusion 5-fluorouracil in patients with advanced colorectal cancer. | Oncology 20040101 |
| Development of and clinical experience with capecitabine (Xeloda) in the treatment of solid tumours. | European journal of oncology nursing : the official journal of European Oncology Nursing Society 20040101 |
| Drug interactions with St John's wort : mechanisms and clinical implications. | Drug safety 20040101 |
| Long-term survivor of gastric small cell carcinoma. | Hepato-gastroenterology 20040101 |
| Weekly irinotecan (CPT-11) in 5-FU heavily pretreated and poor-performance-status patients with advanced colorectal cancer. | Medical oncology (Northwood, London, England) 20040101 |
| Role of DNA mismatch repair in apoptotic responses to therapeutic agents. | Environmental and molecular mutagenesis 20040101 |
| Current perspectives in the treatment of metastatic colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20040101 |
| Chemotherapy for gastro-enteropancreatic endocrine tumours. | Neuroendocrinology 20040101 |
| Fully human IgG and IgM antibodies directed against the carcinoembryonic antigen (CEA) Gold 4 epitope and designed for radioimmunotherapy (RIT) of colorectal cancers. | BMC cancer 20040101 |
| A phase I trial of olanzapine (Zyprexa) for the prevention of delayed emesis in cancer patients: a Hoosier Oncology Group study. | Cancer investigation 20040101 |
| Microsatellite status and cell cycle associated markers in rectal cancer patients undergoing a combined regimen of 5-FU and CPT-11 chemotherapy and radiotherapy. | Anticancer research 20040101 |
| Neoadjuvant therapy of rectal cancer new treatment perspectives. | Tumori 20040101 |
| Modulation of c-Kit/SCF pathway leads to alterations in topoisomerase-I activity in small cell lung cancer. | Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20040101 |
| UGT1A10 is responsible for SN-38 glucuronidation and its expression in human lung cancers. | Anticancer research 20040101 |
| Combined irinotecan and oxaliplatin in patients with advanced pre-treated pancreatic cancer. | Oncology 20040101 |
| The in vitro effect of gefitinib ('Iressa') alone and in combination with cytotoxic chemotherapy on human solid tumours. | BMC cancer 20040101 |
| Carcinoma of unknown primary site: sequential treatment with paclitaxel/carboplatin/etoposide and gemcitabine/irinotecan: a Minnie Pearl Cancer Research Network phase II trial. | The oncologist 20040101 |
| Role of new agents in the treatment of colorectal cancer. | Surgical oncology 20040101 |
| Salvage chemotherapy with mitomycin, docetaxel, and irinotecan (MDI regimen) in metastatic pancreatic adenocarcinoma: a phase I and II trial. | Cancer investigation 20040101 |
| Capecitabine: fixed daily dose and continuous (noncyclic) dosing schedule. | Cancer investigation 20040101 |
| Low overexpression of HER-2/neu in advanced colorectal cancer limits the usefulness of trastuzumab (Herceptin) and irinotecan as therapy. A phase II trial. | Cancer investigation 20040101 |
| [Recent results of irinotecan therapy in colorectal cancer]. | Magyar onkologia 20040101 |
| Rapid tumor lysis syndrome in a patient with metastatic colon cancer as a complication of treatment with 5-fluorouracil/leucoverin and irinotecan. | Tumori 20040101 |
| Prevention of irinotecan-induced diarrhea by oral sodium bicarbonate and influence on pharmacokinetics. | Oncology 20040101 |
| Cisplatin down-regulates topoisomerase I activity in lung cancer cell lines. | Anticancer research 20040101 |
| Establishment of a 7-ethyl-10-hydroxy-camptothecin-resistant small cell lung cancer cell line. | Anticancer research 20040101 |
| Systemic treatment of colorectal cancer in Serbia: what have we done and what can we offer in the new century? | Acta chirurgica Iugoslavica 20040101 |
| (Neo)adjuvant strategies of advanced gastric carcinoma: time for a change? | Digestive diseases (Basel, Switzerland) 20040101 |
| Antitumor activity of beta-cyclodextrin polymer-camptothecin conjugates. | Molecular pharmaceutics 20040101 |
| Phase I study of postoperative radiotherapy with concomitant weekly irinotecan, 5- fluorouracil and folinic acid in locally advanced rectal cancer. | Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20040101 |
| Progress in treatment of small-cell lung cancer: role of CPT-11. | British journal of cancer 20031215 |
| Combination chemotherapy in advanced gastrointestinal cancers: ex vivo sensitivity to gemcitabine and mitomycin C. | British journal of cancer 20031215 |
| Single amino acid substitutions in the transmembrane domains of breast cancer resistance protein (BCRP) alter cross resistance patterns in transfectants. | International journal of cancer 20031210 |
| Theanine and glutamate transporter inhibitors enhance the antitumor efficacy of chemotherapeutic agents. | Biochimica et biophysica acta 20031205 |
| Second-line chemotherapy with low-dose CPT-11 and cisplatin for colorectal cancer resistant to 5-FU-based chemotherapy. | Cancer chemotherapy and pharmacology 20031201 |
| Two different schedules of irinotecan (CPT-11) in patients with advanced colorectal carcinoma relapsing after a 5-fluorouracil and leucovorin combination. A randomized study. | Cancer chemotherapy and pharmacology 20031201 |
| Increased expression of CEA and MHC class I in colorectal cancer cell lines exposed to chemotherapy drugs. | Journal of cancer research and clinical oncology 20031201 |
| Oesophageal cancer: new developments in systemic therapy. | Cancer treatment reviews 20031201 |
| A phase I and pharmacokinetic study of irinotecan in patients with hepatic or renal dysfunction or with prior pelvic radiation: CALGB 9863. | Annals of oncology : official journal of the European Society for Medical Oncology 20031201 |
| Novel chemotherapeutic agents for the treatment of glioblastoma multiforme. | Expert opinion on investigational drugs 20031201 |
| Haplotype analysis of ABCB1/MDR1 blocks in a Japanese population reveals genotype-dependent renal clearance of irinotecan. | Pharmacogenetics 20031201 |
| Prognostic factors for survival in patients with advanced oesophageal cancer treated with cisplatin-based combination chemotherapy. | British journal of cancer 20031201 |
| Protracted infusional 5-fluorouracil plus high-dose folinic acid combined with bolus mitomycin C in patients with gastrointestinal cancer: a phase I/II dose escalation study. | British journal of cancer 20031201 |
| Efficacy of cytotoxic agents used in the treatment of testicular germ cell tumours under normoxic and hypoxic conditions in vitro. | British journal of cancer 20031201 |
| A sensitive and rapid liquid chromatography tandem mass spectrometry method for quantitative determination of 7-ethyl-10-hydroxycamptothecin (SN-38) in human plasma containing liposome-based SN-38 (LE-SN38). | Biomedical chromatography : BMC 20031201 |
| Chemotherapy for ovarian cancer: yesterday, today and tomorrow. | British journal of cancer 20031201 |
| Resistance to chemotherapy in advanced ovarian cancer: mechanisms and current strategies. | British journal of cancer 20031201 |
| Docetaxel: promising and novel combinations in ovarian cancer. | British journal of cancer 20031201 |
| Weekly docetaxel for patients with platinum/paclitaxel/irinotecan-resistant relapsed ovarian cancer: a phase I study. | International journal of clinical oncology 20031201 |
| Phase I study of irinotecan and S-1 combination therapy in patients with metastatic gastric cancer. | International journal of clinical oncology 20031201 |
| Complications of gastrectomy following CPT-11-based neoadjuvant chemotherapy for gastric cancer. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20031201 |
| Perioperative complications in patients undergoing major liver resection with or without neoadjuvant chemotherapy. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20031201 |
| A Phase II study of weekly irinotecan and capecitabine in patients with previously treated non-small cell lung cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20031201 |
| Glucuronidation as a mechanism of intrinsic drug resistance in human colon cancer: reversal of resistance by food additives. | Cancer research 20031201 |
| Drug-drug interaction pharmacokinetic study with the Raf kinase inhibitor (RKI) BAY 43-9006 administered in combination with irinotecan (CPT-11) in patients with solid tumors. | International journal of clinical pharmacology and therapeutics 20031201 |
| [Concurrent chemoradiation experience of recurrent gastric cancers resistant to TS-1]. | Gan to kagaku ryoho. Cancer & chemotherapy 20031201 |
| [Palliative therapy of colorectal cancer]. | Onkologie 20031201 |
| [Chemotherapy of advanced colorectal carcinoma: treatment options for elderly patients]. | Onkologie 20031201 |
| [Novel molecular approaches in the therapy of advanced colorectal carcinoma]. | Onkologie 20031201 |
| Chemosensitization and radiosensitization of human cancer by antisense anti-MDM2 oligonucleotides: in vitro and in vivo activities and mechanisms. | Annals of the New York Academy of Sciences 20031201 |
| The toxicity rates of two different regimens of irinotecan. | Hepato-gastroenterology 20031201 |
| Repair of and checkpoint response to topoisomerase I-mediated DNA damage. | Mutation research 20031127 |
| [Patient with stomach cancer with metastases. What is the value of chemotherapy?]. | MMW Fortschritte der Medizin 20031127 |
| A phase II trial of capecitabine (Xeloda) in recurrent ovarian cancer. | British journal of cancer 20031117 |
| A phase II irinotecan-cisplatin combination in advanced pancreatic cancer. | British journal of cancer 20031117 |
| Prospective randomised phase II study of gemcitabine at standard or fixed dose rate schedule in unresectable hepatocellular carcinoma. | British journal of cancer 20031117 |
| A phase II study of irinotecan plus chronomodulated oxaliplatin, 5-fluorouracil and folinic acid in advanced colorectal cancer patients. | British journal of cancer 20031117 |
| Study of in vitro and in vivo effects of 1,6-Bis[4-(4-amino-3-hydroxyphenoxy)phenyl]diamantane (DPD), a novel cytostatic and differentiation inducing agent, on human colon cancer cells. | British journal of cancer 20031117 |
| c-Myc overexpression sensitises colon cancer cells to camptothecin-induced apoptosis. | British journal of cancer 20031103 |
| Ex vivo analysis of topotecan: advancing the application of laboratory-based clinical therapeutics. | British journal of cancer 20031103 |
| Alleviation of side effects induced by irinotecan hydrochloride (CPT-11) in rats by intravenous infusion. | Cancer chemotherapy and pharmacology 20031101 |
| Sensitive HPLC-fluorescence method for irinotecan and four major metabolites in human plasma and saliva: application to pharmacokinetic studies. | Clinical chemistry 20031101 |
| Weekly regimen of irinotecan/docetaxel in previously treated non-small cell lung cancer patients and correlation with uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) polymorphism. | Investigational new drugs 20031101 |
| Activity of weekly irinotecan (CPT-11) in patients with advanced non-small cell lung cancer pretreated with platinum and taxanes. | Investigational new drugs 20031101 |
| Enhancement of in vivo antitumor activity of classical anticancer agents by combination with the new, glutathione-interacting DNA minor groove-binder, brostallicin. | Clinical cancer research : an official journal of the American Association for Cancer Research 20031101 |
| Activation of a camptothecin prodrug by specific carboxylesterases as predicted by quantitative structure-activity relationship and molecular docking studies. | Molecular cancer therapeutics 20031101 |
| [Chemotherapy for gastric cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20031101 |
| [Chemotherapy for colorectal carcinoma]. | Gan to kagaku ryoho. Cancer & chemotherapy 20031101 |
| [A case of advanced cancer with liver metastasis and paraaortic lymph node metastasis responding remarkably to combination chemotherapy of low-dose CDDP, 5-FU and CPT-11]. | Gan to kagaku ryoho. Cancer & chemotherapy 20031101 |
| [A case of gastric carcinoma with multiple skin, bone, and bilateral ovary metastasis; effective treatment by chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20031101 |
| Presentations from the Walter Reed Army Medical Center. Case 1: rectal carcinoma. | Oncology (Williston Park, N.Y.) 20031101 |
| [Campto (CPT-11) treatment of advanced large intestinal cancer: clinical experience]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20031101 |
| Overview of chemotherapy-induced diarrhea. | Seminars in oncology nursing 20031101 |
| Development of new agents for the treatment of advanced colorectal cancer. | Clinical colorectal cancer 20031101 |
| A multicenter phase II study of irinotecan in patients with advanced colorectal cancer previously treated with 5-fluorouracil. | Clinical colorectal cancer 20031101 |
| Randomized trial comparing the addition of oxaliplatin or irinotecan to high-dose leucovorin and 5-Fluorouracil intravenous bolus every two weeks in metastatic colorectal carcinoma: Southern Italy Cooperative Oncology Group 0103. | Clinical colorectal cancer 20031101 |
| Biweekly irinotecan plus bolus 5-fluorouracil and folinic acid in patients with advanced stage colorectal cancer. | Japanese journal of clinical oncology 20031101 |
| [A case of isolated hepatic malignant lymphoma representing characteristic findings on radiological imaging]. | Fukuoka igaku zasshi = Hukuoka acta medica 20031101 |
| Oxaliplatin- or irinotecan-based chemotherapy for metastatic colorectal cancer in the elderly. | British journal of cancer 20031020 |
| Mechanisms of resistance to topoisomerase I-targeting drugs. | Oncogene 20031020 |
| Phase I and pharmacokinetic study of two different schedules of oxaliplatin, irinotecan, Fluorouracil, and leucovorin in patients with solid tumors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031015 |
| Therapeutic strategies for metastatic colorectal cancer: simultaneous, sequential, or specific? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031015 |
| A phase I study of irinotecan as a 3-week schedule in children with refractory or recurrent solid tumors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031015 |
| Carboxylesterases expressed in human colon tumor tissue and their role in CPT-11 hydrolysis. | Clinical cancer research : an official journal of the American Association for Cancer Research 20031015 |
| A prodrug strategy using ONYX-015-based replicating adenoviruses to deliver rabbit carboxylesterase to tumor cells for conversion of CPT-11 to SN-38. | Cancer research 20031015 |
| Modified de Gramont with oxaliplatin in the first-line treatment of advanced colorectal cancer. | British journal of cancer 20031006 |
| First-line gemcitabine with cisplatin or epirubicin in advanced non-small-cell lung cancer: a phase III trial. | British journal of cancer 20031006 |
| Increased NF-kappaB DNA binding but not transcriptional activity during apoptosis induced by the COX-2-selective inhibitor NS-398 in colorectal carcinoma cells. | British journal of cancer 20031006 |
| Determination of irinotecan (CPT-11) and SN-38 in human whole blood and red blood cells by liquid chromatography with fluorescence detection. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031005 |
| A multicenter phase II study of irinotecan (CPT-11) alternated with 5-fluorouracil and leucovorin as first-line treatment of patients with metastatic colorectal cancer. | Cancer chemotherapy and pharmacology 20031001 |
| Colorectal cancer: integrating oxaliplatin. | Current treatment options in oncology 20031001 |
| Novel functional polymorphisms in the UGT1A7 and UGT1A9 glucuronidating enzymes in Caucasian and African-American subjects and their impact on the metabolism of 7-ethyl-10-hydroxycamptothecin and flavopiridol anticancer drugs. | The Journal of pharmacology and experimental therapeutics 20031001 |
| Multimodal therapy with intravenous biweekly leucovorin, 5-fluorouracil and irinotecan combined with hepatic arterial infusion pirarubicin in non-resectable hepatic metastases from colorectal cancer (a European Association for Research in Oncology trial). | Annals of oncology : official journal of the European Society for Medical Oncology 20031001 |
| Review article: colorectal cancer chemotherapy. | Alimentary pharmacology & therapeutics 20031001 |
| Platinum retreatment of platinum-resistant ovarian cancer after nonplatinum therapy. | Gynecologic oncology 20031001 |
| Apoptotic pathways of epothilone BMS 310705. | Gynecologic oncology 20031001 |
| Second-line treatment in advanced colon cancer: are multiple phase II trials informative enough to guide clinical practice? | Anti-cancer drugs 20031001 |
| Weekly high-dose 5-fluorouracil as 24-h infusion and folinic acid (AIO) plus irinotecan as second- and third-line treatment in patients with colorectal cancer pre-treated with AIO plus oxaliplatin. | Anti-cancer drugs 20031001 |
| Selective serotonin reuptake inhibitor-induced rhabdomyolysis associated with irinotecan. | Southern medical journal 20031001 |
| [Treatment of metastatic liver carcinoma: chemotherapy and immunotherapy]. | Nihon Geka Gakkai zasshi 20031001 |
| [The platelet-sparing effect of carboplatin and docetaxel combination chemotherapy for lung cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20031001 |
| [Retrospective study on utility of irinotecan hydrochloride in patients with advanced and recurrent breast cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20031001 |
| Systemic therapy for colorectal cancer: focus on newer chemotherapy and novel agents. | Seminars in radiation oncology 20031001 |
| Chemotherapeutic and biologic agents as radiosensitizers in rectal cancer. | Seminars in radiation oncology 20031001 |
| Irinotecan as salvage chemotherapy for advanced small bowel adenocarcinoma: a series of three patients. | Journal of chemotherapy (Florence, Italy) 20031001 |
| Irinotecan (Campto) in the treatment of pancreatic cancer. | Expert review of anticancer therapy 20031001 |
| [Experimental study on intraperitoneal versus intravenous CPT-11 for peritoneal seeding and liver metastasis]. | Gan to kagaku ryoho. Cancer & chemotherapy 20031001 |
| [A case of resected spinal metastasis following colectomy and hepatectomy for descending colon carcinoma]. | Gan to kagaku ryoho. Cancer & chemotherapy 20031001 |
| [A case of hepatic metastasis and local recurrence from rectal cancer responding to hepatic arterial infusion and systemic chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20031001 |
| [A case of unresectable liver metastases from rectosigmoid colon cancer with survival for over 3 years after multidisciplinary treatment]. | Gan to kagaku ryoho. Cancer & chemotherapy 20031001 |
| [A case of spinal infarction related to hepatic arterial infusion chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20031001 |
| [Long-term survival after neck lymph node metastases from sigmoid colon cancer--a case report]. | Gan to kagaku ryoho. Cancer & chemotherapy 20031001 |
| [Two patients with metastatic ovarian tumor (Krukenberg's tumor) of gastric origin who underwent oophorectomy with paraaortic and intrapelvic lymph node dissection]. | Gan to kagaku ryoho. Cancer & chemotherapy 20031001 |
| An oncology perspective on the benefits and cost of combined androgen blockade in advanced prostate cancer. | The Canadian journal of urology 20031001 |
| Current treatment and future directions in neuroblastoma. | Indian journal of pediatrics 20031001 |
| Irinotecan (CPT-11) in metastatic colorectal cancer patients resistant to 5-fluorouracil (5-FU): a phase II study. | Methods and findings in experimental and clinical pharmacology 20031001 |
| Are there any better camptothecins than the ones we have? | Clinical advances in hematology & oncology : H&O 20031001 |
| Pharmacogenomics: road to anticancer therapeutics nirvana? | Oncogene 20030929 |
| Simple non-ion-paired high-performance liquid chromatographic method for simultaneous quantitation of carboxylate and lactone forms of 14 new camptothecin derivatives. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030925 |
| Irinotecan plus leucovorin-modulated 5-fluorouracil I.V. bolus every other week may be a suitable therapeutic option also for elderly patients with metastatic colorectal carcinoma. | British journal of cancer 20030915 |
| Irinotecan is active in chemonaive patients with metastatic gastric cancer: a phase II multicentric trial. | British journal of cancer 20030915 |
| Phase II study of cisplatin, ifosfamide, and irinotecan with rhG-CSF support in patients with stage IIIb and IV non-small-cell lung cancer. | British journal of cancer 20030915 |
| Irinotecan in patients with relapsed or cisplatin-refractory germ cell cancer: a phase II study of the German Testicular Cancer Study Group. | British journal of cancer 20030915 |
| Cisplatin in combination with either gemcitabine or irinotecan in carcinomas of unknown primary site: results of a randomized phase II study--trial for the French Study Group on Carcinomas of Unknown Primary (GEFCAPI 01). | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030915 |
| Microsatellite instability is a predictive factor of the tumor response to irinotecan in patients with advanced colorectal cancer. | Cancer research 20030915 |
| Irinotecan causes severe small intestinal damage, as well as colonic damage, in the rat with implanted breast cancer. | Journal of gastroenterology and hepatology 20030901 |
| Comment: Usefulness of herbal and dietary supplement references. | The Annals of pharmacotherapy 20030901 |
| Treatment of T4 tumours: the role of radiotherapy. | Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20030901 |
| Individualised dosing strategy for high-dose carboplatin in patients with germ cell cancer. | British journal of cancer 20030901 |
| Phase I/II study of docetaxel and cisplatin with concurrent thoracic radiation therapy for locally advanced non-small-cell lung cancer. | British journal of cancer 20030901 |
| Phase I/II study of daily carboplatin, 5-fluorouracil and concurrent radiation therapy for locally advanced non-small-cell lung cancer. | British journal of cancer 20030901 |
| Plasma concentrations of 5-fluorouracil and F-beta-alanine following oral administration of S-1, a dihydropyrimidine dehydrogenase inhibitory fluoropyrimidine, as compared with protracted venous infusion of 5-fluorouracil. | British journal of cancer 20030901 |
| Combination of TRAIL gene therapy and chemotherapy enhances antitumor and antimetastasis effects in chemosensitive and chemoresistant breast cancers. | Molecular therapy : the journal of the American Society of Gene Therapy 20030901 |
| Phase I/II study of hepatic arterial therapy with floxuridine and dexamethasone in combination with intravenous irinotecan as adjuvant treatment after resection of hepatic metastases from colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030901 |
| Capecitabine and irinotecan as first-line chemotherapy in patients with metastatic colorectal cancer: results of an extended phase I study. | Annals of oncology : official journal of the European Society for Medical Oncology 20030901 |
| Weekly treatment with irinotecan, folinic acid and infusional 5-fluorouracil (ILF) in patients with advanced gastric cancer. | Anti-cancer drugs 20030901 |
| [Controversial issues in chemotherapy for inoperable gastric cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20030901 |
| [Controversy of treatment for advanced colorectal cancer--intermedisine]. | Gan to kagaku ryoho. Cancer & chemotherapy 20030901 |
| PG490-88, a derivative of triptolide, causes tumor regression and sensitizes tumors to chemotherapy. | Molecular cancer therapeutics 20030901 |
| Phase II trial of irinotecan (CPT-11) in relapsed or refractory non-Hodgkin's lymphomas. | Leukemia & lymphoma 20030901 |
| Irinotecan and other agents in upper gastrointestinal and colorectal carcinomas. The University of Texas M. D. Anderson Cancer Center Investigators' Workshop, Volume 3. Introduction. | Oncology (Williston Park, N.Y.) 20030901 |
| Irinotecan and paclitaxel in metastatic adenocarcinoma of the esophagus and gastric cardia. | Oncology (Williston Park, N.Y.) 20030901 |
| Irinotecan and fixed-dose-rate gemcitabine in advanced pancreatic and biliary cancer: phase I study. | Oncology (Williston Park, N.Y.) 20030901 |
| Irinotecan/cisplatin followed by 5-FU/paclitaxel/radiotherapy and surgery in esophageal cancer. | Oncology (Williston Park, N.Y.) 20030901 |
| Gemcitabine and irinotecan in locally advanced or metastatic biliary cancer: preliminary report. | Oncology (Williston Park, N.Y.) 20030901 |
| Phase II study of docetaxel and irinotecan in metastatic or recurrent esophageal cancer: a preliminary report. | Oncology (Williston Park, N.Y.) 20030901 |
| Irinotecan in esophageal cancer. | Oncology (Williston Park, N.Y.) 20030901 |
| Improving the toxicity of irinotecan/5-FU/leucovorin: a 21-day schedule. | Oncology (Williston Park, N.Y.) 20030901 |
| [Polymorphism in colorectal cancer]. | Nihon rinsho. Japanese journal of clinical medicine 20030901 |
| [Chemotherapy for colon cancer]. | Nihon rinsho. Japanese journal of clinical medicine 20030901 |
| [Application and problems in hepatic arterial infusion chemotherapy]. | Nihon rinsho. Japanese journal of clinical medicine 20030901 |
| [Home chemotherapy and outpatient treatment for metastatic colorectal cancer]. | Nihon rinsho. Japanese journal of clinical medicine 20030901 |
| [5-fluorouracil and leucovorin therapy for advanced colorectal cancer]. | Nihon rinsho. Japanese journal of clinical medicine 20030901 |
| [Irinotecan plus fluorouracil and leucovorin for advanced colorectal cancer]. | Nihon rinsho. Japanese journal of clinical medicine 20030901 |
| [Present status of chemotherapy for colorectal cancer in countries outside of Japan]. | Nihon rinsho. Japanese journal of clinical medicine 20030901 |
| [Toxicities associated with chemotherapy in colorectal cancer]. | Nihon rinsho. Japanese journal of clinical medicine 20030901 |
| [Radiotherapy for locally relapsed rectal cancer]. | Nihon rinsho. Japanese journal of clinical medicine 20030901 |
| [Therapeutic approach for colorectal cancer with topoisomerase as a molecular target]. | Nihon rinsho. Japanese journal of clinical medicine 20030901 |
| [Guidance and informed consent in colon cancer therapy]. | Nihon rinsho. Japanese journal of clinical medicine 20030901 |
| Influence of clinical parameters on quality of life during chemotherapy in patients with advanced non-small cell lung cancer: application of a general linear model. | Japanese journal of clinical oncology 20030901 |
| Nanoparticle drug delivery system for intravenous delivery of topoisomerase inhibitors. | Journal of controlled release : official journal of the Controlled Release Society 20030828 |
| [Treatment of patients with liver metastases from colorectal cancer. More patients can benefit from the treatment!]. | Lakartidningen 20030828 |
| Onycholysis associated with capecitabine in combination with irinotecan in two patients with colorectal cancer. | Journal of the National Cancer Institute 20030820 |
| Phase I study of cisplatin, irinotecan, and epirubicin administered every 3 weeks in patients with advanced solid tumours. | British journal of cancer 20030818 |
| Phase II trial of irinotecan plus docetaxel in cisplatin-pretreated relapsed or refractory oesophageal cancer. | British journal of cancer 20030818 |
| Irinotecan pathway genotype analysis to predict pharmacokinetics. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030815 |
| Hypersensitivity reactions related to oxaliplatin (OHP). | British journal of cancer 20030804 |
| Feasibility of quality of life assessment in patients with upper gastrointestinal tract cancer. | British journal of cancer 20030804 |
| Functional characterization of human UDP-glucuronosyltransferase 1A9 variant, D256N, found in Japanese cancer patients. | The Journal of pharmacology and experimental therapeutics 20030801 |
| Phase II study of biweekly irinotecan and mitomycin C combination therapy in patients with fluoropyrimidine-resistant advanced colorectal cancer. | Cancer chemotherapy and pharmacology 20030801 |
| Randomized study of dexamethasone treatment for delayed emesis, anorexia and fatigue induced by irinotecan. | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20030801 |
| Advanced NSCLC: new cytostatic agents. | Lung cancer (Amsterdam, Netherlands) 20030801 |
| Carboxylesterase-mediated sensitization of human tumor cells to CPT-11 cannot override ABCG2-mediated drug resistance. | Molecular pharmacology 20030801 |
| Intestinal permeability in colorectal cancer patients treated by raltitrexed or irinotecan. | Journal of clinical gastroenterology 20030801 |
| Intracellular conversion of irinotecan to its active form, SN-38, by native carboxylesterase in human non-small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20030801 |
| Preoperative hyperfractionated accelerated radiotherapy (HART) and concomitant CPT-11 in locally advanced rectal carcinoma: a phase I study. | International journal of radiation oncology, biology, physics 20030801 |
| A phase I/II study of oral uracil/tegafur (UFT), leucovorin and irinotecan in patients with advanced colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20030801 |
| Safety and toxicity analysis of oxaliplatin combined with fluorouracil or as a single agent in patients with previously treated advanced colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030801 |
| Phase I trial of escalating-dose irinotecan given weekly with cisplatin and concurrent radiotherapy in locally advanced esophageal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030801 |
| Missing evidence for the adequacy of a 1-cm distal margin in resected rectal cancer. | Annals of surgical oncology 20030801 |
| Tailoring chemotherapy in advanced colorectal cancer. | Current opinion in pharmacology 20030801 |
| Apoptosis induction in prostate cancer cells and xenografts by combined treatment with Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand and CPT-11. | Cancer research 20030801 |
| Phase I clinical and pharmacokinetic study of irinotecan in adults with recurrent malignant glioma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030801 |
| Expression and functional analyses of breast cancer resistance protein in lung cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030801 |
| Clinical and cellular pharmacology in relation to solid tumours of childhood. | Cancer treatment reviews 20030801 |
| [A case of multiple lung metastases from colon cancer after sigmoidectomy treated effectively by chemotherapy]. | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20030801 |
| Second-line chemotherapy for non-small cell lung cancer. | Expert review of anticancer therapy 20030801 |
| Role of targeted therapy in non-small cell lung cancer: hype or hope? | Expert review of anticancer therapy 20030801 |
| [A patient with peritoneal metastasis from gastric cancer who responded to weekly chemotherapy with paclitaxel on the third line and could take meal]. | Gan to kagaku ryoho. Cancer & chemotherapy 20030801 |
| [A case of effective weekly paclitaxel administration for metastatic gastric cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20030801 |
| Gene-directed enzyme prodrug therapy for osteosarcoma: sensitization to CPT-11 in vitro and in vivo by adenoviral delivery of a gene encoding secreted carboxylesterase-2. | Molecular cancer therapeutics 20030801 |
| Validation of the role of angiogenesis as a chemotherapeutic target. | Clinical colorectal cancer 20030801 |
| Adding a humanized antibody to vascular endothelial growth factor (Bevacizumab, Avastin) to chemotherapy improves survival in metastatic colorectal cancer. | Clinical colorectal cancer 20030801 |
| Capecitabine in combination with irinotecan or oxaliplatin in advanced colorectal cancer. | Clinical colorectal cancer 20030801 |
| The latest advances in chemotherapy for gastrointestinal cancers. | International journal of clinical oncology 20030801 |
| 5-fluorouracil as a protracted continuous infusion plus irinotecan (CPT-11) in patients with advanced colorectal cancer treated with fluoropyrimidine-based regimens as first line. | Anti-cancer drugs 20030801 |
| Quantitation of dihydropyrimidine dehydrogenase (DPD) mRNA expression levels in normal colon and colorectal cancer tumor paraffin-embedded tissue specimens. | Anti-cancer drugs 20030801 |
| CPT-11 and cisplatin in the treatment of advanced gastric cancer in Asians. | Journal of chemotherapy (Florence, Italy) 20030801 |
| New perspectives in the management of pancreas cancer. | Seminars in oncology 20030801 |
| Current and ongoing trials with irinotecan in the United States. | Seminars in oncology 20030801 |
| Alternative schedules with irinotecan. | Seminars in oncology 20030801 |
| Induction therapy in patients with metastatic colorectal cancer. | Seminars in oncology 20030801 |
| Recent experience with oxaliplatin or irinotecan combined with 5-fluorouracil and leucovorin in the treatment of colorectal cancer. | Seminars in oncology 20030801 |
| Evolving role of irinotecan in small-cell lung cancer. | Clinical advances in hematology & oncology : H&O 20030801 |
| Enhanced effectiveness of last generation antiblastic compounds vs. cisplatin on malignant pleural mesothelioma cell lines. | European journal of pharmacology 20030725 |
| Experimental design and sample size determination for testing synergism in drug combination studies based on uniform measures. | Statistics in medicine 20030715 |
| Determination by liquid chromatography with fluorescence detection of total 7-ethyl-10-hydroxy-camptothecin (SN-38) in beagle dog plasma after intravenous administration of liposome-based SN-38 (LE-SN38). | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030705 |
| Phase I/II study of escalating doses of nedaplatin in combination with irinotecan for advanced non-small-cell lung cancer. | Cancer chemotherapy and pharmacology 20030701 |
| Dramatic response of multiply relapsed hepatoblastoma to irinotecan (CPT-11). | Medical and pediatric oncology 20030701 |
| A pilot study of irinotecan (CPT-11) as single-agent therapy in patients with locally advanced or metastatic esophageal carcinoma. | International journal of colorectal disease 20030701 |
| Is liver disease an octreotide side effect? | Journal of clinical gastroenterology 20030701 |
| A phase II study of irinotecan in patients with advanced renal cell carcinoma. | Cancer 20030701 |
| A randomized phase II trial of irinotecan in combination with infusional or two different bolus 5-fluorouracil and folinic acid regimens as first-line therapy for advanced colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20030701 |
| Multicenter phase II trial evaluating a three-weekly schedule of irinotecan plus raltitrexed in patients with 5-fluorouracil-refractory advanced colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20030701 |
| Antisense Bcl-xl down-regulation switches the response to topoisomerase I inhibition from senescence to apoptosis in colorectal cancer cells, enhancing global cytotoxicity. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030701 |
| Combination chemotherapy with irinotecan and ifosfamide as second-line treatment of refractory or sensitive relapsed small cell lung cancer: a phase II study. | Chemotherapy 20030701 |
| Population-based maximum tolerated dose of irinotecan and carboplatin. | Oncology (Williston Park, N.Y.) 20030701 |
| Dose-dense therapy with a novel irinotecan regimen for small-cell lung cancer. | Oncology (Williston Park, N.Y.) 20030701 |
| Irinotecan, cisplatin/carboplatin, and COX-2 inhibition in small-cell lung cancer. | Oncology (Williston Park, N.Y.) 20030701 |
| Irinotecan and carboplatin in metastatic or recurrent non-small-cell lung cancer. | Oncology (Williston Park, N.Y.) 20030701 |
| The global role of irinotecan in the treatment of lung cancer: 2003 update. | Oncology (Williston Park, N.Y.) 20030701 |
| A novel red fluorescent protein orthotopic pancreatic cancer model for the preclinical evaluation of chemotherapeutics. | The Journal of surgical research 20030701 |
| Pharmacology of intraperitoneal CPT-11. | Surgical oncology clinics of North America 20030701 |
| Compassionate use programme of irinotecan in colorectal cancer patients in The Netherlands. | The Netherlands journal of medicine 20030701 |
| Phase I study of weekly alternating therapy with irinotecan/cisplatin and etoposide/cisplatin for patients with small-cell lung cancer. | Clinical lung cancer 20030701 |
| Diagnosis and therapy for advanced esophageal cancer. | Current opinion in gastroenterology 20030701 |
| A review of systemic therapy for advanced pancreatic cancer. | Clinical advances in hematology & oncology : H&O 20030701 |
| The camptothecins. | Lancet (London, England) 20030628 |
| Effect of antivascular endothelial growth factor treatment on the intratumoral uptake of CPT-11. | British journal of cancer 20030616 |
| Differential effects of the breast cancer resistance protein on the cellular accumulation and cytotoxicity of 9-aminocamptothecin and 9-nitrocamptothecin. | Cancer research 20030615 |
| Superiority of oxaliplatin and fluorouracil-leucovorin compared with either therapy alone in patients with progressive colorectal cancer after irinotecan and fluorouracil-leucovorin: interim results of a phase III trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030601 |
| In vitro effects of combinations of cis-amminedichloro (2-methylpyridine) platinum (II) (ZD0473) with other novel anticancer drugs on the growth of SBC-3, a human small cell lung cancer cell line. | Lung cancer (Amsterdam, Netherlands) 20030601 |
| Phase II study of irinotecan and carboplatin in patients with the refractory or relapsed small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20030601 |
| Heterogeneity of chemosensitivity of colorectal adenocarcinoma determined by a modified ex vivo ATP-tumor chemosensitivity assay (ATP-TCA). | Anti-cancer drugs 20030601 |
| Bimonthly leucovorin, infusion 5-fluorouracil, hydroxyurea, and irinotecan (FOLFIRI-2) for pretreated metastatic colorectal cancer. | American journal of clinical oncology 20030601 |
| Phase II clinical study of irinotecan and cisplatin as first-line chemotherapy in metastatic or recurrent cervical cancer. | Gynecologic oncology 20030601 |
| The interaction of thymidylate synthase expression with p53-regulated signaling pathways in tumor cells. | Seminars in oncology 20030601 |
| Development of ZD1839 in colorectal cancer. | Seminars in oncology 20030601 |
| Optimal use of the combination of irinotecan and 5-fluorouracil. | Seminars in oncology 20030601 |
| Effect of P-glycoprotein modulator, cyclosporin A, on the gastrointestinal excretion of irinotecan and its metabolite SN-38 in rats. | Pharmaceutical research 20030601 |
| [Recent advances in chemotherapy for digestive cancers with special references to gastric and colonic cancers]. | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20030601 |
| [Chemotherapy-induced diarrhea]. | Gan to kagaku ryoho. Cancer & chemotherapy 20030601 |
| [A case of gastric cancer with multiple liver metastasis responding to combination therapy of CPT-11 and CDDP]. | Gan to kagaku ryoho. Cancer & chemotherapy 20030601 |
| Phase II study of irinotecan and mitomycin C in 5-fluorouracil-pretreated patients with advanced colorectal and gastric cancer. | Journal of chemotherapy (Florence, Italy) 20030601 |
| Chemotherapy with irinothecan, 5-fluorouracil and folinic acid in the first-line management of advanced colorectal carcinoma: retrospective study. | Journal of chemotherapy (Florence, Italy) 20030601 |
| Advances in colon cancer. | Drug news & perspectives 20030601 |
| Nitro and amino substitution in the D-ring of 5-(2-dimethylaminoethyl)- 2,3-methylenedioxy-5H-dibenzo[c,h][1,6]naphthyridin-6-ones: effect on topoisomerase-I targeting activity and cytotoxicity. | Journal of medicinal chemistry 20030522 |
| Prophylactic options in patients with 5-fluorouracil-associated cardiotoxicity. | British journal of cancer 20030519 |
| Analysis of the time course and prognostic factors determining toxicity due to infused fluorouracil. | British journal of cancer 20030519 |
| IPM chemotherapy in cytokine refractory renal cell cancer. | British journal of cancer 20030519 |
| High-performance liquid chromatographic assay with fluorescence detection for the simultaneous measurement of carboxylate and lactone forms of irinotecan and three metabolites in human plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030505 |
| Status of treatment for advanced gastric carcinoma. | Current oncology reports 20030501 |
| Preventive effect of Kampo medicine (Hangeshashin-to) against irinotecan-induced diarrhea in advanced non-small-cell lung cancer. | Cancer chemotherapy and pharmacology 20030501 |
| Randomized phase II study of cisplatin, irinotecan and etoposide combinations administered weekly or every 4 weeks for extensive small-cell lung cancer (JCOG9902-DI). | Annals of oncology : official journal of the European Society for Medical Oncology 20030501 |
| Prevention of irinotecan plus 5-fluorouracil/leucovorin-induced diarrhoea by oral administration of neomycin plus bacitracin in first-line treatment of advanced colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20030501 |
| Irinotecan in the treatment of glioma patients: current and future studies of the North Central Cancer Treatment Group. | Cancer 20030501 |
| The emerging role of irinotecan (CPT-11) in the treatment of malignant glioma in brain tumors. | Cancer 20030501 |
| Combination therapy with irinotecan and protein kinase C inhibitors in malignant glioma. | Cancer 20030501 |
| Effect of intrapatient dosage escalation of irinotecan on its pharmacokinetics in pediatric patients who have high-grade gliomas and receive enzyme-inducing anticonvulsant therapy. | Cancer 20030501 |
| Two studies evaluating irinotecan treatment for recurrent malignant glioma using an every-3-week regimen. | Cancer 20030501 |
| Pilot trial of intravenous infusion of a replication-selective adenovirus (ONYX-015) in combination with chemotherapy or IL-2 treatment in refractory cancer patients. | Cancer gene therapy 20030501 |
| Thermal enhancement of new chemotherapeutic agents at moderate hyperthermia. | Annals of surgical oncology 20030501 |
| Clinical update: proteasome inhibitors in solid tumors. | Cancer treatment reviews 20030501 |
| Phase I evaluation of sequential topoisomerase targeting with irinotecan/cisplatin followed by etoposide in patients with advanced malignancy. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030501 |
| Pharmacogenetics of irinotecan. | Current medicinal chemistry. Anti-cancer agents 20030501 |
| Overview of preoperative and postoperative therapy for colorectal cancer: the European and United States perspectives. | Clinical colorectal cancer 20030501 |
| [A case of colon cancer with liver metastases and lymph node metastases successfully treated with surgery followed by CPT-11 and 5-FU chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20030501 |
| Irinotecan: promising activity in the treatment of malignant glioma. | Oncology (Williston Park, N.Y.) 20030501 |
| Improvement of radiotherapy or chemoradiotherapy by targeting COX-2 enzyme. | Oncology (Williston Park, N.Y.) 20030501 |
| Rationale for mitomycin and irinotecan use in advanced breast cancer. | Oncology (Williston Park, N.Y.) 20030501 |
| Japanese ovarian trials: focus on irinotecan. | Oncology (Williston Park, N.Y.) 20030501 |
| Toxicity associated with carboplatin/paclitaxel/Irinotecan use in advanced ovarian cancer: preliminary analysis. | Oncology (Williston Park, N.Y.) 20030501 |
| Phase I. Trial of irinotecan plus carboplatin in two dose schedules. | Oncology (Williston Park, N.Y.) 20030501 |
| Phase I. Trial of irinotecan and temozolomide in patients with solid tumors. | Oncology (Williston Park, N.Y.) 20030501 |
| Combined inhibition of topoisomerases: a phase I. Study of irinotecan and epirubicin. | Oncology (Williston Park, N.Y.) 20030501 |
| Irinotecan treatment in cancer patients with UGT1A1 polymorphisms. | Oncology (Williston Park, N.Y.) 20030501 |
| Combination chemotherapy with docetaxel and irinotecan in metastatic malignant melanoma. | Clinical oncology (Royal College of Radiologists (Great Britain)) 20030501 |
| Phlebitis due to irinotecan. | Clinical oncology (Royal College of Radiologists (Great Britain)) 20030501 |
| [Renal metastasis after curative resection of an epidermoid carcinoma of the esophagus]. | Gastroenterologie clinique et biologique 20030501 |
| Concurrent radiation therapy and irinotecan in stage IIIB cervical cancer. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20030501 |
| Irinotecan plus raltitrexed vs raltitrexed alone in patients with gemcitabine-pretreated advanced pancreatic adenocarcinoma. | British journal of cancer 20030422 |
| Serum markers of matrix turnover as predictors for the evolution of colorectal cancer metastasis under chemotherapy. | British journal of cancer 20030422 |
| Expression profiles of non-small cell lung cancers on cDNA microarrays: identification of genes for prediction of lymph-node metastasis and sensitivity to anti-cancer drugs. | Oncogene 20030410 |
| Neoadjuvant systemic fluorouracil and mitomycin C prior to synchronous chemoradiation is an effective strategy in locally advanced rectal cancer. | British journal of cancer 20030407 |
| Combination chemotherapy for advanced colorectal cancer. | British journal of cancer 20030407 |
| Multicentre phase II study and pharmacokinetic analysis of irinotecan in chemotherapy-naïve patients with glioblastoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20030401 |
| Lipid membrane with low proton permeability. | Biochimica et biophysica acta 20030401 |
| Dramatic effect of ZD1839 ('Iressa') in a patient with advanced non-small-cell lung cancer and poor performance status. | Lung cancer (Amsterdam, Netherlands) 20030401 |
| Longer time interval between completion of neoadjuvant chemoradiation and surgical resection does not improve downstaging of rectal carcinoma. | Diseases of the colon and rectum 20030401 |
| Chemopotentiation of temozolomide, irinotecan, and cisplatin activity by CEP-6800, a poly(ADP-ribose) polymerase inhibitor. | Molecular cancer therapeutics 20030401 |
| [Drug-resistant proteins in breast cancer: recent progress in multidrug resistance]. | Ai zheng = Aizheng = Chinese journal of cancer 20030401 |
| Irinotecan in the treatment of advanced colorectal cancer in patients pretreated with Fluorouracil-based chemotherapy: a study to determine recommendable therapeutic dosage. | American journal of clinical oncology 20030401 |
| [A case of irinotecan-resistant colon cancer responding to chronotherapy with oxaliplatin, 5-FU, l-LV]. | Gan to kagaku ryoho. Cancer & chemotherapy 20030401 |
| Efficacy of chemoradiotherapy on pain relief in patients with intrapelvic recurrence of rectal cancer. | Japanese journal of clinical oncology 20030401 |
| Nonsteroidal anti-inflammatory drugs in colorectal cancer: from prevention to therapy. | British journal of cancer 20030324 |
| Phase I/II trial of weekly cisplatin, etoposide, and irinotecan chemotherapy for metastatic lung cancer: JCOG 9507. | British journal of cancer 20030324 |
| Cancer pharmacogenomics: current and future applications. | Biochimica et biophysica acta 20030317 |
| Phase I and pharmacokinetic study of intravenous irinotecan plus oral ciclosporin in patients with fuorouracil-refractory metastatic colon cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030315 |
| Synthesis and cytotoxic activity of carboxamide derivatives of benzo[b][1,6]naphthyridines. | Journal of medicinal chemistry 20030313 |
| Cancer chemotherapy: a SN-38 (7-ethyl-10-hydroxycamptothecin) glucuronide prodrug for treatment by a PMT (Prodrug MonoTherapy) strategy. | Bioorganic & medicinal chemistry letters 20030310 |
| EORTC Early Clinical Studies Group early phase II trial of S-1 in patients with advanced or metastatic colorectal cancer. | British journal of cancer 20030310 |
| CPT-11-induced cell death in leukemic cells is not affected by the MDR phenotype. | Leukemia research 20030301 |
| Treatment of pancreatic cancer with a combination of irinotecan (CPT-11) and gemcitabine: a multicenter phase II study by the Greek Cooperative Group for Pancreatic Cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20030301 |
| An open phase I study assessing the feasibility of the triple combination: oxaliplatin plus irinotecan plus leucovorin/ 5-fluorouracil every 2 weeks in patients with advanced solid tumors. | Annals of oncology : official journal of the European Society for Medical Oncology 20030301 |
| Recent advances in the pharmacological treatment of colorectal cancer. | Expert opinion on investigational drugs 20030301 |
| Phase III comparison of two irinotecan dosing regimens in second-line therapy of metastatic colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030301 |
| Concern about similarity of manuscripts. | Clinical pharmacology and therapeutics 20030301 |
| [A case of metastatic liver tumor of colorectal cancer responding to low-dose CPT-11 chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20030301 |
| Weekly hepatic arterial infusion of 5-fluorouracil and subsequent systemic chemotherapy for liver metastases from colorectal cancer. | Japanese journal of clinical oncology 20030301 |
| Irinotecan (CPT11) plus high-dose 5-fluorouracil (5-FU) and leucovorin (LV) as salvage therapy for metastatic colorectal cancer (MCRC) after failed oxaliplatin plus 5-FU and LV: a pilot study in Taiwan. | Japanese journal of clinical oncology 20030301 |
| [Severe acute cytomegalovirus colitis after administration of irinotecan and raltitrexed chemotherapy]. | Gastroenterologie clinique et biologique 20030301 |
| [A case of paraneoplastic syndrome improved following chemoradiotherapy for lung cancer]. | Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20030301 |
| [A symphony for the camptothecins]. | Bulletin du cancer 20030301 |
| Experimental therapy of human prostate cancer by inhibiting MDM2 expression with novel mixed-backbone antisense oligonucleotides: in vitro and in vivo activities and mechanisms. | The Prostate 20030215 |
| Minidose warfarin prophylaxis for catheter-associated thrombosis in cancer patients: can it be safely associated with fluorouracil-based chemotherapy? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030215 |
| Randomised phase III trial of irinotecan combined with cisplatin for advanced non-small-cell lung cancer. | British journal of cancer 20030210 |
| Successful clinical response to irinotecan in relapsed neuroblastoma. | Medical and pediatric oncology 20030201 |
| Limited stage small cell lung cancer: treatment and therapy. | Current treatment options in oncology 20030201 |
| p53-mediated regulation of expression of a rabbit liver carboxylesterase confers sensitivity to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11). | The Journal of pharmacology and experimental therapeutics 20030201 |
| High-performance liquid chromatographic analysis of the anticancer drug irinotecan (CPT-11) and its active metabolite SN-38 in human plasma. | Therapeutic drug monitoring 20030201 |
| Inhibition of cyclooxygenase-2 by rofecoxib attenuates the growth and metastatic potential of colorectal carcinoma in mice. | Cancer research 20030201 |
| Hepatic artery infusion for liver metastases from colorectal cancer. | Lancet (London, England) 20030201 |
| Phase I clinical and pharmacologic study of weekly cisplatin and irinotecan combined with amifostine for refractory solid tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030201 |
| Three-week schedule of irinotecan and cisplatin in advanced non-small cell lung cancer: a multicentre phase II study. | Lung cancer (Amsterdam, Netherlands) 20030201 |
| Phase II trial of CPT-11 in myelodysplastic syndromes with excess of marrow blasts. | Leukemia 20030201 |
| Activity and safety of a low dose, fractional administration of irinotecan hydrochloride (CPT-11) in combination with cisplatin for relapsed gastric cancer patients: a preliminary report. | International journal of clinical oncology 20030201 |
| [Current status and future perspectives in chemotherapy for testicular cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20030201 |
| [Optimal dosing schedule in combination therapy with irinotecan and doxifluridine in a human colorectal cancer xenograft model]. | Gan to kagaku ryoho. Cancer & chemotherapy 20030201 |
| [A phase I study of gemcitabine and irinotecan as second line treatment for advanced non-small cell lung cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20030201 |
| The combination of capecitabine and oxaliplatin in metastatic colorectal cancer. | Clinical colorectal cancer 20030201 |
| Adjuvant radiation therapy of patients with rectal cancer. | Clinical colorectal cancer 20030201 |
| Predictive markers for colorectal cancer: current status and future prospects. | Clinical colorectal cancer 20030201 |
| Phase I/IIA randomized study of PHY906, a novel herbal agent, as a modulator of chemotherapy in patients with advanced colorectal cancer. | Clinical colorectal cancer 20030201 |
| Chemotherapy for small cell lung cancer. | Seminars in oncology 20030201 |
| [Economic assessment of adjuvant and palliative chemotherapy in colorectal cancer: a review]. | Bulletin du cancer 20030201 |
| Potentiation of chemotherapeutic agents following antagonism of nuclear factor kappa B in human gliomas. | Journal of neuro-oncology 20030201 |
| [Genetic polymorphisms on drug metabolizing enzymes in relation to anti-cancer drug effectiveness]. | Rinsho byori. The Japanese journal of clinical pathology 20030201 |
| [Chemotherapy for colorectal cancers]. | Journal de chirurgie 20030201 |
| Chemotherapy for malignant pleural mesothelioma: past results and recent developments. | British journal of cancer 20030127 |
| Cell kinetics-dependent antitumor effect of irinotecan hydrochloride induced by the synchronizing effect of hydroxyurea: cell kinetics and dosing time. | Life sciences 20030124 |
| Phase II trial of irinotecan in patients with metastatic epithelial ovarian cancer or peritoneal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030115 |
| Docetaxel induction therapy in locally advanced squamous cell carcinoma of the head and neck. | British journal of cancer 20030113 |
| Multicenter phase II study of fractionated bimonthly oxaliplatin with leucovorin and 5-fluorouracil in patients with metastatic colorectal cancer, pre-treated with chemotherapy. | Oncology reports 20030101 |
| Homocamptothecins: potent topoisomerase I inhibitors and promising anticancer drugs. | Critical reviews in oncology/hematology 20030101 |
| Mouse liver and kidney carboxylesterase (M-LK) rapidly hydrolyzes antitumor prodrug irinotecan and the N-terminal three quarter sequence determines substrate selectivity. | Drug metabolism and disposition: the biological fate of chemicals 20030101 |
| Glucuronidation of 7-ethyl-10-hydroxycamptothecin (SN-38), an active metabolite of irinotecan (CPT-11), by human UGT1A1 variants, G71R, P229Q, and Y486D. | Drug metabolism and disposition: the biological fate of chemicals 20030101 |
| Breast cancer resistance protein (BCRP/ABCG2) induces cellular resistance to HIV-1 nucleoside reverse transcriptase inhibitors. | Molecular pharmacology 20030101 |
| Phase II trial of preoperative 3D conformal radiotherapy, protracted venous infusion 5-fluorouracil, and weekly CPT-11, followed by surgery for ultrasound-staged T3 rectal cancer. | International journal of radiation oncology, biology, physics 20030101 |
| Recent advances in traditional plant drugs and orchids. | Acta pharmacologica Sinica 20030101 |
| Colorectal cancer in the elderly: is palliative chemotherapy of value? | Drugs & aging 20030101 |
| Antitumor properties of irinotecan-containing nanoparticles prepared using poly(DL-lactic acid) and poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol). | Biological & pharmaceutical bulletin 20030101 |
| Safety and efficacy of outpatient treatment with CPT-11 plus bolus folinic acid/5-fluorouracil as first-line chemotherapy for metastatic colorectal cancer. | Anti-cancer drugs 20030101 |
| The role of the ubiquitination-proteasome pathway in breast cancer: applying drugs that affect the ubiquitin-proteasome pathway to the therapy of breast cancer. | Breast cancer research : BCR 20030101 |
| Modulators of ceramide metabolism sensitize colorectal cancer cells to chemotherapy: a novel treatment strategy. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20030101 |
| Pharmacokinetic study of two infusion schedules of irinotecan combined with cisplatin in patients with advanced gastric cancer. | Oncology 20030101 |
| Lessons learned from the irinotecan metabolic pathway. | Current medicinal chemistry 20030101 |
| A Phase II study of irinotecan in combination with 120-h infusion of 5-fluorouracil in patients with metastatic colorectal carcinoma: Japan Clinical Oncology Group Study (JCOG9703). | Japanese journal of clinical oncology 20030101 |
| The effect of whole-body hyperthermia combined with 'metronomic' chemotherapy on rat mammary adenocarcinoma metastases. | International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 20030101 |
| Developments in the systemic therapy of pancreatic cancer. | Cancer investigation 20030101 |
| Expression profiling of blood samples from an SU5416 Phase III metastatic colorectal cancer clinical trial: a novel strategy for biomarker identification. | BMC cancer 20030101 |
| Phase II study of weekly irinotecan (CPT-11) as second-line treatment of patients with advanced colorectal cancer. | Medical oncology (Northwood, London, England) 20030101 |
| Recent advances in colorectal cancer therapy. | Cancer biology & therapy 20030101 |
| Fractionated administration of irinotecan and cisplatin for treatment of extensive-disease small-cell lung cancer: a phase II study. | Anticancer research 20030101 |
| Camptothecin analogues and vinblastine in the treatment of renal cell carcinoma: an in vivo study using a human orthotopic renal cancer xenograft. | Urologic oncology 20030101 |
| Oxaliplatin: a new drug for the treatment of metastatic carcinoma of the colon or rectum. | Reviews in gastroenterological disorders 20030101 |
| Antitumor activity of new combination chemotherapy with irinotecan hydrochloride and nedaplatin against human cervical cancer cell lines. | Oncology reports 20030101 |
| Second-line chemotherapy with combined irinotecan and low-dose cisplatin for patients with metastatic gastric carcinoma resistant to 5-fluorouracil. | Oncology reports 20030101 |
| The modulation of irinotecan-induced diarrhoea and pharmacokinetics by three different classes of pharmacologic agents. | Oncology reports 20030101 |
| [Cytoreductive surgery of liver metastasis from colorectal cancer: principles of intra-arterial regional chemotherapy]. | Khirurgiia 20030101 |
| Adjuvant therapy for colon cancer in the new millenium. | Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society 20030101 |
| Palliative treatment of patients with colorectal cancer. | Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society 20030101 |
| A novel carbazole topoisomerase II poison, ER-37328: potent tumoricidal activity against human solid tumors in vitro and in vivo. | Cancer science 20030101 |
| A phase II study of docetaxel-irinotecan combination in advanced pancreatic cancer. | Hepato-gastroenterology 20030101 |
| Implications of genetic testing in the management of colorectal cancer. | American journal of pharmacogenomics : genomics-related research in drug development and clinical practice 20030101 |
| Phase II study of irinotecan and ifosfamide in patients with advanced non-small cell lung cancer. | Oncology 20030101 |
| Gemcitabine plus irinotecan in breast cancer patients pretreated with taxanes and anthracyclines: a multicenter phase II study. | Oncology 20030101 |
| S-1 in gastric cancer: a comprehensive review. | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20030101 |
| Metastatic colorectal cancer: systemic treatment in the new millennium. | Cancer control : journal of the Moffitt Cancer Center 20030101 |
| Salvage chemotherapy with a combination of irinotecan hydrochloride and mitomycin C in platinum- and paclitaxel-resistant epithelial ovarian cancer: case reports. | European journal of gynaecological oncology 20030101 |
| Epidemiology, treatment and chemoprevention in colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20030101 |
| Metastatic colorectal cancer: integrating irinotecan into combination and sequential chemotherapy. | Annals of oncology : official journal of the European Society for Medical Oncology 20030101 |
| Chemotherapy and surgery: new perspectives on the treatment of unresectable liver metastases. | Annals of oncology : official journal of the European Society for Medical Oncology 20030101 |
| Irinotecan in metastatic colorectal cancer: dose intensification and combination with new agents, including biological response modifiers. | Annals of oncology : official journal of the European Society for Medical Oncology 20030101 |
| Colorectal cancer in the adjuvant setting: perspectives on treatment and the role of prognostic factors. | Annals of oncology : official journal of the European Society for Medical Oncology 20030101 |
| Irinotecan in the treatment of gastric cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20030101 |
| Future strategies and adjuvant treatment of gastric cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20030101 |
| Current treatments and future perspectives in colorectal and gastric cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20030101 |
| Adjuvant chemotherapy using CPT-11, leucovorin plus bolus 5-fluorouracil and radiotherapy in patients with rectal cancer. A feasibility study. | Anticancer research 20030101 |
| Biomodulation of cancer chemotherapy for metastatic colorectal cancer: a randomized study of weekly low-dose irinotecan alone versus irinotecan plus the oncostatic pineal hormone melatonin in metastatic colorectal cancer patients progressing on 5-fluorouracil-containing combinations. | Anticancer research 20030101 |
| Chemotherapy for advanced pancreatic cancer. | International journal of radiation oncology, biology, physics 20030101 |
| Weekly irinotecan in patients with metastatic colorectal cancer failing 5-fluorouracil-based chemotherapy: efficacy and prognostic factors. | Tumori 20030101 |
| Irinotecan enhances IL-12 production by OK-432-activated murine macrophages. | Anticancer research 20030101 |
| Epidermal growth factor receptor inhibition induces trichomegaly. | Acta oncologica (Stockholm, Sweden) 20030101 |
| Pharmacogenetics of stomach cancer. | I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.] 20030101 |
| Treatment of advanced disease and new drugs. | I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.] 20030101 |
| Multicenter phase II study of CPT-11 fractionated over two days with bimonthly leucovorin and 5-fluorouracil in patients with metastatic colorectal cancer. | Anticancer research 20030101 |
| Raltitrexed and mitomycin-C as third-line chemotherapy for colorectal cancer after combination regimens including 5-fluorouracil, irinotecan and oxaliplatin: a phase II study. | Anticancer research 20030101 |
| Phase I study of combination chemotherapy using irinotecan hydrochloride and nedaplatin for advanced or recurrent cervical cancer. | Oncology 20030101 |
| Current chemotherapy for glioblastoma. | Cancer journal (Sudbury, Mass.) 20030101 |
| Oxaliplatin: a review of its use in combination therapy for advanced metastatic colorectal cancer. | Drugs 20030101 |
| SNP analysis by using ferrocenyl naphthalene diimide (FND)-based electrochemical hybridization assay (EHA). | Nucleic acids research. Supplement (2001) 20030101 |
| Biweekly administration regimen of docetaxel combined with CPT-11 in patients with inoperable or recurrent gastric cancer. | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20030101 |
| Prodrugs in genetic chemoradiotherapy. | Current pharmaceutical design 20030101 |
| Biweekly low-dose sequential gemcitabine, 5-fluorouracil, leucovorin, and cisplatin (GFP): a highly active novel therapy for metastatic adenocarcinoma of the exocrine pancreas. | Cancer investigation 20030101 |
| A phase II study of modified deGramont 5-fluorouracil, leucovorin, and oxaliplatin in previously treated patients with metastatic colorectal cancer. | Cancer investigation 20030101 |
| The relative contributions of carboxylesterase and beta-glucuronidase in the formation of SN-38 in human colorectal tumours. | Oncology reports 20030101 |
| [The update on pancreatic cancer chemotherapy]. | Medicina (Kaunas, Lithuania) 20030101 |
| Are herbal remedies and dietary supplements safe and effective for breast cancer patients? | Breast cancer research : BCR 20030101 |
| Health food store recommendations: implications for breast cancer patients. | Breast cancer research : BCR 20030101 |
| Clinical studies of camptothecin and derivatives. | The Alkaloids. Chemistry and biology 20030101 |
| Radiotherapy and oral capecitabine in the preoperative treatment of patients with rectal cancer: rationale, preliminary results and perspectives. | Tumori 20030101 |
| Irinotecan hepatic arterial infusion chemotherapy for hepatic metastases from colorectal cancer: a phase II clinical study. | Tumori 20030101 |
| Single-agent irinotecan as second-line treatment for advanced gastric cancer. | Tumori 20030101 |
| Cisplatin and irinotecan (CPT-11) for peritoneal mesothelioma. | Cancer investigation 20030101 |
| Combined modality therapy in esophageal cancer: the Memorial experience. | Seminars in surgical oncology 20030101 |
| An update on hepatic arterial infusion chemotherapy for colorectal cancer. | The oncologist 20030101 |
| Palliative cytostatic treatment of cervical carcinoma. | European journal of gynaecological oncology 20030101 |
| Irinotecan and gemcitabine in patients with advanced non-small cell lung cancer, previously treated with cisplatin-based chemotherapy. A phase II study. | Anticancer research 20030101 |
| Unexpected interactions between nicotinamide and CPT-11 in a rhabdomyosarcoma tumor model. | Anticancer research 20030101 |
| Effective weekly docetaxel for recurrent ovarian cancer: A case report. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20030101 |
| Innovative chemotherapies for stage III colon cancer: a cost-effectiveness study. | Hepato-gastroenterology 20030101 |
| A phase II study with CPT-11 plus leucovorin and bolus IV 5-fluorouracil in patients with advanced colorectal carcinoma. | Cancer investigation 20030101 |
| New developments in systemic chemotherapy in advanced colorectal cancer. | Scandinavian journal of gastroenterology. Supplement 20030101 |
| [Systemic treatment of colorectal cancers--factual standards and perspectives]. | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20030101 |
| Gemcitabine and carboplatin regimens in advanced non-small-cell lung cancer: focus on randomized phase III trials. | Clinical lung cancer 20030101 |
| [Novel combinations of irinotecan with molecular-targeted drugs in the treatment of colorectal carcinoma]. | Tumori 20030101 |
| Short-time infusion of oxaliplatin (Eloxatin) in combination with capecitabine (Xeloda) in patients with advanced colorectal cancer. | Acta oncologica (Stockholm, Sweden) 20030101 |
| Understanding and managing chemotherapy-induced diarrhea. | The journal of supportive oncology 20030101 |
| Eight novel single nucleotide polymorphisms in ABCG2/BCRP in Japanese cancer patients administered irinotacan. | Drug metabolism and pharmacokinetics 20030101 |
| Twelve novel single nucleotide polymorphisms in the CES2 gene encoding human carboxylesterase 2 (hCE-2). | Drug metabolism and pharmacokinetics 20030101 |
| Effect of composition on the stability of liposomal irinotecan prepared by a pH gradient method. | Journal of bioscience and bioengineering 20030101 |
| Colon cancer. Clinical practice guidelines in oncology. | Journal of the National Comprehensive Cancer Network : JNCCN 20030101 |
| Rectal cancer. Clinical practice guidelines in oncology. | Journal of the National Comprehensive Cancer Network : JNCCN 20030101 |
| Toxicological implications of hepatobiliary transporters. | Toxicology 20021227 |
| Erbitux trial flawed from the beginning, committee finds. | Journal of the National Cancer Institute 20021218 |
| Model of chemotherapy-induced myelosuppression with parameter consistency across drugs. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20021215 |
| Triplet chemotherapy with vinorelbine, gemcitabine, and cisplatin for advanced non-small cell lung cancer: a phase II study. | British journal of cancer 20021202 |
| Complete response to radiation therapy in a patient with chemotherapy-resistant ovarian clear cell adenocarcinoma. | Archives of gynecology and obstetrics 20021201 |
| Phase II study of irinotecan and carboplatin for advanced non-small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20021201 |
| Irinotecan: mechanisms of tumor resistance and novel strategies for modulating its activity. | Annals of oncology : official journal of the European Society for Medical Oncology 20021201 |
| Irinotecan combined with bolus 5-fluorouracil and folinic acid Nordic schedule as first-line therapy in advanced colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20021201 |
| Oxaliplatin plus irinotecan and leucovorin-modulated 5-fluorouracil triplet regimen every other week: a dose-finding study in patients with advanced gastrointestinal malignancies. | Annals of oncology : official journal of the European Society for Medical Oncology 20021201 |
| Early detection of toxicity and adjustment of ongoing clinical trials: the history and performance of the North Central Cancer Treatment Group's real-time toxicity monitoring program. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20021201 |
| Pharmacokinetics of irinotecan and its metabolites. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20021201 |
| Developing therapeutic pharmaceuticals for the treatment of soft-tissue sarcomas. | Expert opinion on investigational drugs 20021201 |
| Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups. | Pharmacogenetics 20021201 |
| Second-line chemotherapy in relapsing or refractory patients with non-small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20021201 |
| Novel therapeutic approaches in the treatment of children with hepatoblastoma. | Journal of pediatric hematology/oncology 20021201 |
| Oxaliplatin with high-dose leucovorin and infusional 5-fluorouracil in irinotecan-pretreated patients with advanced colorectal cancer (ACC). | American journal of clinical oncology 20021201 |
| Challenging the platinum combinations in the chemotherapy of NSCLC. | Lung cancer (Amsterdam, Netherlands) 20021201 |
| Adjuvant and neoadjuvant treatments for NSCLC. | Lung cancer (Amsterdam, Netherlands) 20021201 |
| Molecular markers and targeted therapy with novel agents: prospects in the treatment of non-small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20021201 |
| Population pharmacokinetic model for irinotecan and two of its metabolites, SN-38 and SN-38 glucuronide. | Clinical pharmacology and therapeutics 20021201 |
| New drugs for the treatment of cancer, 1990-2001. | The Israel Medical Association journal : IMAJ 20021201 |
| Capecitabine/irinotecan in colorectal cancer: European early-phase data and planned trials. | Oncology (Williston Park, N.Y.) 20021201 |
| Current status of capecitabine in the treatment of colorectal cancer. | Oncology (Williston Park, N.Y.) 20021201 |
| [Effectiveness of chemotherapy for outpatients with gastric or colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20021201 |
| Weekly oxaliplatin, high-dose folinic acid and 24h-5-fluorouracil (FUFOX) as salvage therapy in metastatic colorectal cancer patients pretreated with irinotecan and folinic acid/5-fluorouracil regimens. | Zeitschrift fur Gastroenterologie 20021201 |
| Pemetrexed: single-agent and combination phase I study overview. | Seminars in oncology 20021201 |
| The role of pemetrexed in the treatment of colorectal cancer. | Seminars in oncology 20021201 |
| Gemcitabine in the treatment of advanced pancreatic cancer: a comparative analysis of randomized trials. | Seminars in oncology 20021201 |
| Future directions in the treatment of pancreatic cancer. | Seminars in oncology 20021201 |
| [New strategies in the treatment of esophageal cancer]. | Minerva chirurgica 20021201 |
| Comprehensive evaluation of carboxylesterase-2 expression in normal human tissues using tissue array analysis. | Applied immunohistochemistry & molecular morphology : AIMM 20021201 |
| The mechanism of topoisomerase I poisoning by a camptothecin analog. | Proceedings of the National Academy of Sciences of the United States of America 20021126 |
| Prognostic role of serum vascular endothelial growth factor, basic fibroblast growth factor and nitric oxide in patients with colorectal carcinoma. | Cytokine 20021124 |
| Phase II study of irinotecan with bolus and high dose infusional 5-FU and folinic acid (modified de Gramont) for first or second line treatment of advanced or metastatic colorectal cancer. | British journal of cancer 20021118 |
| Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ. | The Journal of biological chemistry 20021115 |
| Phosphorylation of chk1 at serine-345 affected by topoisomerase I poison SN-38. | International journal of oncology 20021101 |
| The importance of tumor glucuronidase in the activation of irinotecan in a mouse xenograft model. | The Journal of pharmacology and experimental therapeutics 20021101 |
| Irinotecan plus cisplatin has substantial antitumor effect as salvage chemotherapy against germ cell tumors. | Cancer 20021101 |
| Dosage adjustment and pharmacokinetic profile of irinotecan in cancer patients with hepatic dysfunction. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20021101 |
| Use of a topoisomerase I inhibitor (irinotecan, CPT-11) in metastatic adrenocortical carcinoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20021101 |
| Non-platinum gemcitabine combinations in non-small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20021101 |
| Unexpected pleural effusions in 3 pediatric patients treated with STI-571. | Journal of pediatric hematology/oncology 20021101 |
| Adding weekly irinotecan to high-dose 5-fluorouracil and folinic acid (HD-5-FU/FA) after failure for first-line HD-5-FU/FA in advanced colorectal cancer--a phase II study. | Anti-cancer drugs 20021101 |
| High-dose, single-agent irinotecan as first-line therapy in the treatment of metastatic colorectal cancer. | Cancer chemotherapy and pharmacology 20021101 |
| [Glutamate transporter mediated increase of antitumor activity by theanine, an amino acid in green tea]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20021101 |
| [A case of AFP-producing gastric cancer with multiple liver metastases responding to CPT-11 and cisplatin combination chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20021101 |
| [Two patients with recurrent colon cancer who underwent surgery following a combination of irinotecan and UFT]. | Gan to kagaku ryoho. Cancer & chemotherapy 20021101 |
| [Dysarthria during irinotecan administration]. | La Revue de medecine interne 20021101 |
| Highlights from: 27th congress of the European Society for Medical Oncology. Nice, France. October 18-22, 2002. | Clinical colorectal cancer 20021101 |
| Perspectives on the role of sequential or combination chemotherapy for first-line and salvage therapy in advanced colorectal cancer. | Clinical colorectal cancer 20021101 |
| Systemic chemotherapy for metastatic colorectal cancer: reasons to combine. | Clinical colorectal cancer 20021101 |
| Combination of 5-fluorouracil and irinotecan on modulation of thymidylate synthase and topoisomerase I expression and cell cycle regulation in human colon cancer LoVo cells: clinical relevance. | Clinical colorectal cancer 20021101 |
| [A case of postoperative liver metastasis of alpha-fetoprotein producing gastric cancer successfully treated with intrahepatic chemotherapy (adriamycin, cisplatin, irinotecan hydrochloride)]. | Gan to kagaku ryoho. Cancer & chemotherapy 20021101 |
| [Pharmacokinetic study of CPT-11, SN-38 and SN-38 glucuronide in the ascites, plasma and bile after intraperitoneal administration of CPT-11]. | Gan to kagaku ryoho. Cancer & chemotherapy 20021101 |
| [A case of ovarian cancer in which a remarkable effect was seen with low-dose CDDP intratumoral injection of CPT-11]. | Gan to kagaku ryoho. Cancer & chemotherapy 20021101 |
| [Hepatic arterial infusion with irinotecan for the colorectal cancer patient with liver metastasis--a case report]. | Gan to kagaku ryoho. Cancer & chemotherapy 20021101 |
| [A case of stage IV diffusely infiltrating colon cancer treated by surgical resection and chemoradiation therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20021101 |
| [A case of gastric cancer associated with synchronous liver metastasis successfully treated with combination therapy of systemic and hepatic arterial infusion chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20021101 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20021101 |
| [Gastrointestinal toxicity caused by irinotecan in the case of preexistent passage problems]. | Nederlands tijdschrift voor geneeskunde 20021026 |
| [Therapy of colorectal carcinoma in internal medicine]. | Praxis 20021023 |
| Contribution of apoptosis in the cytotoxicity of the oxaliplatin-irinotecan combination in the HT29 human colon adenocarcinoma cell line. | Biochemical pharmacology 20021015 |
| Cyclooxygenase-2 inhibition with celecoxib enhances antitumor efficacy and reduces diarrhea side effect of CPT-11. | Cancer research 20021015 |
| Effects of tumor necrosis factor-related apoptosis-inducing ligand alone and in combination with chemotherapeutic agents on patients' colon tumors grown in SCID mice. | Cancer research 20021015 |
| Platinum drugs in the treatment of non-small-cell lung cancer. | British journal of cancer 20021007 |
| Irinotecan, cisplatin and mitomycin in inoperable gastro-oesophageal and pancreatic cancers - a new active regimen. | British journal of cancer 20021007 |
| Phase II trial of irinotecan, paclitaxel and carboplatin in patients with previously untreated Stage IIIB/IV nonsmall cell lung carcinoma. | Cancer 20021001 |
| Biweekly chemotherapy with oxaliplatin, irinotecan, infusional Fluorouracil, and leucovorin: a pilot study in patients with metastatic colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20021001 |
| Phase I and pharmacokinetic study of irinotecan in combination with raltitrexed. | Cancer chemotherapy and pharmacology 20021001 |
| SN-38 induces cell cycle arrest and apoptosis in human testicular cancer. | European urology 20021001 |
| Phase I study of irinotecan and cisplatin with concurrent split-course radiotherapy in limited-disease small-cell lung cancer. | European journal of cancer (Oxford, England : 1990) 20021001 |
| Antitumour activity of three second-line treatment combinations in patients with metastatic colorectal cancer after optimal 5-FU regimen failure: a randomised, multicentre phase II study. | Annals of oncology : official journal of the European Society for Medical Oncology 20021001 |
| A phase I study of sequential irinotecan and 5-fluorouracil/leucovorin. | Annals of oncology : official journal of the European Society for Medical Oncology 20021001 |
| Second-line chemotherapy with irinotecan and vinorelbine in stage IIIB and IV non-small-cell lung cancer: a phase II study. | American journal of clinical oncology 20021001 |
| Phase I clinical trial of irinotecan with oral capecitabine in patients with gastrointestinal and other solid malignancies. | American journal of clinical oncology 20021001 |
| Preclinical activity of an i.v. formulation of rubitecan in IDD-P against human solid tumor xenografts. | Anti-cancer drugs 20021001 |
| Oxaliplatin: results in colorectal carcinoma. | Critical reviews in oncology/hematology 20021001 |
| [A case of colon metastasis to the lung treated successfully with combined chemotherapy of CPT-11 and 5'-DFUR]. | Gan to kagaku ryoho. Cancer & chemotherapy 20021001 |
| The role of oxaliplatin in the treatment of advanced metastatic colorectal cancer: prospects and future directions. | Seminars in oncology 20021001 |
| Safety experience with IMC-C225, an anti-epidermal growth factor receptor antibody. | Seminars in oncology 20021001 |
| DNA topoisomerases in cancer chemotherapy: using enzymes to generate selective DNA damage. | Current opinion in investigational drugs (London, England : 2000) 20021001 |
| Adjuvant therapy in colon cancer: current status and future directions. | Cancer treatment reviews 20021001 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20021001 |
| Epithelial growth factor receptor interacting agents. | Hematology/oncology clinics of North America 20021001 |
| Irinotecan in patients with relapsed or cisplatin-refractory germ cell cancer: a phase II study of the German Testicular Cancer Study Group. | British journal of cancer 20020923 |
| Chemotherapy for advanced non-small-cell lung cancer: who, what, when, why? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020915 |
| Raltitrexed treatment promotes systemic inflammatory reaction in patients with colorectal carcinoma. | British journal of cancer 20020909 |
| A phase I and pharmacokinetic study of MAG-CPT, a water-soluble polymer conjugate of camptothecin. | British journal of cancer 20020909 |
| DNA topoisomerase I and II expression in drug resistant germ cell tumours. | British journal of cancer 20020909 |
| Secreted and tumour targeted human carboxylesterase for activation of irinotecan. | British journal of cancer 20020909 |
| Treatment-related death from chemotherapy and thoracic radiotherapy for advanced cancer. | Panminerva medica 20020901 |
| Pharmacogenomics of human UDP-glucuronosyltransferases and irinotecan toxicity. | Molecular pharmacology 20020901 |
| Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38). | Molecular pharmacology 20020901 |
| Irinotecan and raltitrexed: an active combination in advanced colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20020901 |
| Phase I study of weekly oxaliplatin plus irinotecan in previously treated patients with metastatic colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20020901 |
| Phase I and pharmacokinetic study of paclitaxel and irinotecan for patients with advanced non-small cell lung cancer. | European journal of cancer (Oxford, England : 1990) 20020901 |
| Efficacy and toxicity of a virus-directed enzyme prodrug therapy purging method: preclinical assessment and application to bone marrow samples from neuroblastoma patients. | Cancer research 20020901 |
| Cellular effects of CPT-11 on colon carcinoma cells: dependence on p53 and hMLH1 status. | International journal of cancer 20020901 |
| Phase I study of weekly irinotecan combined with weekly cisplatin in patients with advanced solid tumors. | Chemotherapy 20020901 |
| The impact of pharmacogenomics on gastrointestinal cancer therapy. | Pharmacogenomics 20020901 |
| Small-sample inference for incomplete longitudinal data with truncation and censoring in tumor xenograft models. | Biometrics 20020901 |
| Phase II study of weekly irinotecan and carboplatin for refractory or relapsed small-cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20020901 |
| Clinical pharmacokinetics of irinotecan and its metabolites in relation with diarrhea. | Clinical pharmacology and therapeutics 20020901 |
| Salvage chemotherapy with CPT-11 for recurrent oligodendrogliomas. | Journal of neuro-oncology 20020901 |
| Chronomodulated chemotherapy in metastatic gastrointestinal cancer combining 5-FU and sodium folinate with oxaliplatin, irinotecan or gemcitabine: the Jena experience in 79 patients. | Journal of cancer research and clinical oncology 20020901 |
| [Randomized controlled trials in Japan--lung cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20020901 |
| Significance of nuclear glutathione S-transferase pi in resistance to anti-cancer drugs. | Japanese journal of cancer research : Gann 20020901 |
| Irinotecan in combination with radiation therapy for small-cell and non-small-cell lung cancer. | Oncology (Williston Park, N.Y.) 20020901 |
| Camptothecin and taxane regimens for small-cell lung cancer. | Oncology (Williston Park, N.Y.) 20020901 |
| Irinotecan plus cisplatin in small-cell lung cancer. | Oncology (Williston Park, N.Y.) 20020901 |
| Current role of irinotecan in the treatment of non-small-cell lung cancer. | Oncology (Williston Park, N.Y.) 20020901 |
| Efficacy and tolerability of irinotecan in patients with advanced colorectal cancer in Singapore. | Annals of the Academy of Medicine, Singapore 20020901 |
| Reduced gastrointestinal toxicity following inhibition of the biliary excretion of irinotecan and its metabolites by probenecid in rats. | Pharmaceutical research 20020901 |
| O6-benzylguanine-mediated enhancement of chemotherapy. | Molecular cancer therapeutics 20020901 |
| Establishment and characterization of a cell-line originated from human mucinous cystadenocarcinoma of the ovary. | Human cell 20020901 |
| The case for the introduction of new chemotherapy agents in the treatment of advanced non small cell lung cancer in the wake of the findings of The National Institute of Clinical Excellence (NICE). | British journal of cancer 20020827 |
| Weekly gemcitabine plus Epirubicin as effective chemotherapy for advanced pancreatic cancer: a multicenter phase II study. | British journal of cancer 20020827 |
| St. John's Wort: more implications for cancer patients. | Journal of the National Cancer Institute 20020821 |
| Effects of St. John's wort on irinotecan metabolism. | Journal of the National Cancer Institute 20020821 |
| Nitric oxide-induced Cl- secretion in isolated rat colon is mediated by the release of thromboxane A2. | The Journal of physiology 20020815 |
| Concurrent administration of Docetaxel and Stealth liposomal doxorubicin with radiotherapy in non-small cell lung cancer : excellent tolerance using subcutaneous amifostine for cytoprotection. | British journal of cancer 20020812 |
| A 'modified de Gramont' regimen of fluorouracil, alone and with oxaliplatin, for advanced colorectal cancer. | British journal of cancer 20020812 |
| Preclinical combination chemotherapy of nedaplatin with gemcitabine against gemcitabine-refractory human lung cancer. | Cancer letters 20020808 |
| Pemetrexed disodium combined with oxaliplatin, SN38, or 5-fluorouracil, based on the quantitation of drug interactions in human HT29 colon cancer cells. | International journal of oncology 20020801 |
| Phase I study of weekly CPT-11 (irinotecan)/docetaxel in patients with advanced solid tumors. | Lung cancer (Amsterdam, Netherlands) 20020801 |
| Clinical pharmacokinetics of irinotecan and its metabolites: a population analysis. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020801 |
| Anemia in oncology practice: relation to diseases and their therapies. | American journal of clinical oncology 20020801 |
| Gemcitabine (2',2'-difluoro-2'-deoxycytidine), an antimetabolite that poisons topoisomerase I. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020801 |
| Human carboxylesterase 2 is commonly expressed in tumor tissue and is correlated with activation of irinotecan. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020801 |
| Irinotecan activation by human carboxylesterases in colorectal adenocarcinoma cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020801 |
| Whole-body hyperthermia (41.8 degrees C) combined with bimonthly oxaliplatin, high-dose leucovorin and 5-fluorouracil 48-hour continuous infusion in pretreated metastatic colorectal cancer: a phase II study. | Annals of oncology : official journal of the European Society for Medical Oncology 20020801 |
| Targeting vascular endothelial growth factor in colorectal cancer. | Oncology (Williston Park, N.Y.) 20020801 |
| Phase I trial of irinotecan and epirubicin in advanced cancer. Preliminary report. | Oncology (Williston Park, N.Y.) 20020801 |
| Mitomycin as a modulator of irinotecan anticancer activity. | Oncology (Williston Park, N.Y.) 20020801 |
| Irinotecan in relapsed or refractory non-Hodgkin's lymphomas. Indications of activity in a phase II trial. | Oncology (Williston Park, N.Y.) 20020801 |
| Influence of anticonvulsants on the metabolism and elimination of irinotecan. A North American Brain Tumor Consortium preliminary report. | Oncology (Williston Park, N.Y.) 20020801 |
| Successful salvage therapy of irinotecan for relapsed Hodgkin's lymphoma. | Internal medicine (Tokyo, Japan) 20020801 |
| [Three patients with advanced nonresectable and recurrent gastric cancer responding to chronomodulation chemotherapy with tegafur + cisplatin + isovorin followed by CPT-11 administration]. | Gan to kagaku ryoho. Cancer & chemotherapy 20020801 |
| [CPT-11 hepatic arterial injection plus oral UFT administration for liver metastasis of rectal cancer--report of two cases]. | Gan to kagaku ryoho. Cancer & chemotherapy 20020801 |
| Second-Line Treatment of Advanced Colorectal Cancer with a Biweekly Oxaliplatin plus Irinotecan Combination Regimen. | Onkologie 20020801 |
| [Gemcitabine-based combinations in inoperable pancreatic cancers]. | Bulletin du cancer 20020801 |
| Oxaliplatin combinations as first-line therapy in advanced colorectal cancer. | Clinical colorectal cancer 20020801 |
| N9741: a phase III study comparing irinotecan to oxaliplatin-containing regimens in advanced colorectal cancer. | Clinical colorectal cancer 20020801 |
| The palliative benefit of irinotecan in 5-fluorouracil-refractory colorectal cancer: its prospective evaluation by a Multicenter Canadian Trial. | Clinical colorectal cancer 20020801 |
| Irinotecan in 5-fluorouracil-refractory colorectal cancer. | Clinical colorectal cancer 20020801 |
| Irinotecan, oxaliplatin, and 5-fluorouracil/leucovorin combination chemotherapy in advanced colorectal carcinoma: a phase II study. | Clinical colorectal cancer 20020801 |
| Application of pharmacokinetic modelling to the routine therapeutic drug monitoring of anticancer drugs. | Fundamental & clinical pharmacology 20020801 |
| Systemic therapy for advanced pancreatic cancer. | Expert review of anticancer therapy 20020801 |
| Dose-escalation study of weekly irinotecan and daily carboplatin with concurrent thoracic radiotherapy for unresectable stage III non-small cell lung cancer. | British journal of cancer 20020729 |
| Hepatic cytochrome P450 3A drug metabolism is reduced in cancer patients who have an acute-phase response. | British journal of cancer 20020729 |
| Abrogation of the S phase DNA damage checkpoint results in S phase progression or premature mitosis depending on the concentration of 7-hydroxystaurosporine and the kinetics of Cdc25C activation. | The Journal of biological chemistry 20020719 |
| Irinotecan pharmacokinetics-pharmacodynamics: the clinical relevance of prolonged exposure to SN-38. | British journal of cancer 20020715 |
| Modulation of irinotecan metabolism by ketoconazole. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020715 |
| Drg1, a novel target for modulating sensitivity to CPT-11 in colon cancer cells. | Cancer research 20020715 |
| Chk1 signaling pathways that mediated G(2)M checkpoint in relation to the cellular resistance to the novel topoisomerase I poison BNP1350. | Biochemical and biophysical research communications 20020712 |
| GEM 231, a second-generation antisense agent complementary to protein kinase A RIalpha subunit, potentiates antitumor activity of irinotecan in human colon, pancreas, prostate and lung cancer xenografts. | International journal of oncology 20020701 |
| Antisense oligonucleotide targeted to RIalpha subunit of cAMP-dependent protein kinase (GEM231) enhances therapeutic effectiveness of cancer chemotherapeutic agent irinotecan in nude mice bearing human cancer xenografts: in vivo synergistic activity, pharmacokinetics and host toxicity. | International journal of oncology 20020701 |
| Intestinal transport of irinotecan in Caco-2 cells and MDCK II cells overexpressing efflux transporters Pgp, cMOAT, and MRP1. | Drug metabolism and disposition: the biological fate of chemicals 20020701 |
| Phase I evaluation of prolonged-infusion gemcitabine with irinotecan for relapsed or refractory leukemia or lymphoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020701 |
| Altered irinotecan pharmacokinetics in pediatric high-grade glioma patients receiving enzyme-inducing anticonvulsant therapy. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020701 |
| Novel camptothecin derivative BNP1350 in experimental human ovarian cancer: determination of efficacy and possible mechanisms of resistance. | International journal of cancer 20020701 |
| Nonsurgical methods for liver metastases including cryotherapy, radiofrequency ablation, and infusional treatment: what's new in 2001? | Current opinion in oncology 20020701 |
| Another NICE mess. | The Lancet. Oncology 20020701 |
| [A case-control study of prevention of irinotecan-induced diarrhea: the reducing side effects of irinotecan by oral alkalization combined with control of defecation]. | Gan to kagaku ryoho. Cancer & chemotherapy 20020701 |
| Chemotherapy for metastatic colorectal cancer. | Drug and therapeutics bulletin 20020701 |
| Prevention and treatment of peritoneal carcinomatosis in experimental investigations with CPT-11 and oxaliplatin. | Anti-cancer drugs 20020701 |
| Non-linear pharmacokinetics of irinotecan in mice. | Anti-cancer drugs 20020701 |
| A phase II trial of farnesyl protein transferase inhibitor SCH 66336, given by twice-daily oral administration, in patients with metastatic colorectal cancer refractory to 5-fluorouracil and irinotecan. | Annals of oncology : official journal of the European Society for Medical Oncology 20020701 |
| Cetuximab (Imclone/Merck/Bristol-Myers Squibb). | Current opinion in investigational drugs (London, England : 2000) 20020701 |
| Esophageal carcinoma: surgery, radiotherapy, and chemotherapy. | Current opinion in gastroenterology 20020701 |
| Effective combination chemotherapy with paclitaxel and cisplatin with or without human granulocyte colony-stimulating factor and/or erythropoietin in patients with advanced gastric cancer. | British journal of cancer 20020617 |
| Oxaliplatin plus raltitrexed and leucovorin-modulated 5-fluorouracil i.v. bolus: a salvage regimen for colorectal cancer patients. | British journal of cancer 20020617 |
| [Oral fluoropyrimidines registered for the treatment of metastatic colorectal carcinoma: a possible gain]. | Nederlands tijdschrift voor geneeskunde 20020615 |
| [Drug therapy of colorectal carcinoma]. | Wiener klinische Wochenschrift 20020614 |
| Why hasn't the National Institute been 'NICE' to patients with colorectal cancer? National Institute of Clinical Excellence. | British journal of cancer 20020605 |
| Which endpoints should we use in evaluating the use of novel fluoropyrimidine regimens in colorectal cancer? | British journal of cancer 20020605 |
| Clinical and economic benefits of irinotecan in combination with 5-fluorouracil and folinic acid as first line treatment of metastatic colorectal cancer. | British journal of cancer 20020605 |
| Determination of drug interactions occurring with the metabolic pathways of irinotecan. | Drug metabolism and disposition: the biological fate of chemicals 20020601 |
| Recent and ongoing clinical trials for treating colorectal cancer. | Expert opinion on investigational drugs 20020601 |
| Triplet combination with irinotecan plus oxaliplatin plus continuous-infusion fluorouracil and leucovorin as first-line treatment in metastatic colorectal cancer: a multicenter phase II trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020601 |
| Thalidomide and irinotecan-associated diarrhea. | American journal of clinical oncology 20020601 |
| Weekly chemotherapy with carboplatin, docetaxel and irinotecan in advanced non-small-cell-lung cancer: a phase II study. | European journal of cancer (Oxford, England : 1990) 20020601 |
| Advanced colorectal cancer treatment in Europe: what have we achieved? | Anti-cancer drugs 20020601 |
| Phase I study of carboplatin, irinotecan and docetaxel on a divided schedule with recombinant human granulocyte colony stimulating factor support in patients with stage IIIB or IV non-small cell lung cancer. | Anti-cancer drugs 20020601 |
| Sensitivity to anticancer agents and resistance mechanisms in clear cell carcinoma of the ovary. | Japanese journal of cancer research : Gann 20020601 |
| Cytotoxic effects of 27 anticancer drugs in HeLa and MDR1-overexpressing derivative cell lines. | Biological & pharmaceutical bulletin 20020601 |
| [A case of advanced colon cancer with para-aortic lymph node metastasis responding greatly to treatment by adjuvant chemotherapy of low-dose CPT-11 on an outpatient basis]. | Gan to kagaku ryoho. Cancer & chemotherapy 20020601 |
| Present and future treatment of advanced non-small cell lung cancer. | Seminars in oncology 20020601 |
| Present and future treatment of pancreatic cancer. | Seminars in oncology 20020601 |
| Gemcitabine and pemetrexed (Alimta) in thoracic cancers: present and future perspectives. Introduction and current controversies. | Seminars in oncology 20020601 |
| Comparison of chemosensitivity tests: clonogenic assay versus MTT assay. | Acta medica Okayama 20020601 |
| New studies highlight benefit of Xeloda in new combination treatments for colorectal cancer. | Expert review of anticancer therapy 20020601 |
| ERBITUX as a single agent and in combination in colorectal carcinoma. | Expert review of anticancer therapy 20020601 |
| Addition of either irinotecan or methotrexate to bolus 5-fluorouracil and high-dose folinic acid every 2 weeks in advanced colorectal carcinoma: a randomised study by the Southern Italy Cooperative Oncology Group. | Annals of oncology : official journal of the European Society for Medical Oncology 20020601 |
| Current and future therapeutic approaches in locally advanced (stage III) non-small cell lung cancer. | Seminars in oncology 20020601 |
| Perspectives and opportunities: Docetaxel in the current and future treatment of non-small cell lung cancer. | Seminars in oncology 20020601 |
| Pharmacology of topoisomerase I inhibitors irinotecan (CPT-11) and topotecan. | Current cancer drug targets 20020601 |
| C421A polymorphism in the human breast cancer resistance protein gene is associated with low expression of Q141K protein and low-level drug resistance. | Molecular cancer therapeutics 20020601 |
| Loss of one allele of the p53 gene in the lens epithelial tumor in transgenic mice suppresses apoptosis induced by a topoisomerase I inhibitor (CPT-11). | Cancer letters 20020528 |
| [Irinotekan in spread small cell lung cancer. More studies are required to change the practice]. | Lakartidningen 20020523 |
| Anti-tumour activity and toxicity of the new prodrug 9-aminocamptothecin glucuronide (9ACG) in mice. | British journal of cancer 20020520 |
| Enhanced tumor killing by Apo2L/TRAIL and CPT-11 co-treatment is associated with p21 cleavage and differential regulation of Apo2L/TRAIL ligand and its receptors. | Oncogene 20020516 |
| [New drugs in bronchial cancer]. | Presse medicale (Paris, France : 1983) 20020511 |
| Novel camptothecin derivatives. Part 1: oxyalkanoic acid esters of camptothecin and their in vitro and in vivo antitumor activity. | Bioorganic & medicinal chemistry letters 20020506 |
| Effect of non-steroidal anti-inflammatory drugs on colon carcinoma Caco-2 cell responsiveness to topoisomerase inhibitor drugs. | British journal of cancer 20020506 |
| Predictive values of sex and tumour site for survival benefit from 5FU in colorectal cancer. | British journal of cancer 20020506 |
| Irinotecan in small-cell lung cancer. | The New England journal of medicine 20020502 |
| An analytical method for irinotecan (CPT-11) and its metabolites using a high-performance liquid chromatography: parallel detection with fluorescence and mass spectrometry. | Biomedical chromatography : BMC 20020501 |
| New developments in the treatment of esophageal cancer. | Current oncology reports 20020501 |
| Structural insights into CPT-11 activation by mammalian carboxylesterases. | Nature structural biology 20020501 |
| Systemic treatment of colorectal cancer. | European journal of cancer (Oxford, England : 1990) 20020501 |
| Enhanced antitumor activity of anti-epidermal growth factor receptor monoclonal antibody IMC-C225 in combination with irinotecan (CPT-11) against human colorectal tumor xenografts. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020501 |
| Overexpression of PTEN increases sensitivity to SN-38, an active metabolite of the topoisomerase I inhibitor irinotecan, in ovarian cancer cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020501 |
| Modulation of marrow proliferation and chemosensitivity by tumor-produced cytokines from syngeneic pancreatic tumor lines. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020501 |
| Irinotecan (CPT-11) in patients with advanced colon carcinoma relapsing after 5-fluorouracil-leucovorin combination. | Chemotherapy 20020501 |
| Genetic polymorphisms of the UDP-glucuronosyltransferase 1A7 gene and irinotecan toxicity in Japanese cancer patients. | Japanese journal of cancer research : Gann 20020501 |
| [Current status of the chemotherapy for lung cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20020501 |
| [A case of rectal cancer with multiple liver metastases that responded dramatically to pharmacokinetic modulating chemotherapy/CPT-11 therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20020501 |
| [Usefulness of low-dose irinotecan for multiple lung metastases of cholangiocellular carcinoma after operation--a case report]. | Gan to kagaku ryoho. Cancer & chemotherapy 20020501 |
| [A case of recurrent small cell lung cancer with symptoms improved by nogitecan hydrochloride]. | Gan to kagaku ryoho. Cancer & chemotherapy 20020501 |
| Introduction to colorectal cancer. | Seminars in oncology nursing 20020501 |
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| Irinotecan, cisplatin, and radiation in esophageal cancer. | Oncology (Williston Park, N.Y.) 20020501 |
| Irinotecan/cisplatin in advanced, treated gastric or gastroesophageal junction carcinoma. | Oncology (Williston Park, N.Y.) 20020501 |
| Irinotecan and gemcitabine in patients with solid tumors: phase I trial. | Oncology (Williston Park, N.Y.) 20020501 |
| Irinotecan/gemcitabine followed by twice-weekly gemcitabine/radiation in locally advanced pancreatic cancer. | Oncology (Williston Park, N.Y.) 20020501 |
| Irinotecan in epithelial ovarian cancer. | Oncology (Williston Park, N.Y.) 20020501 |
| Irinotecan for the treatment of cervical cancer. | Oncology (Williston Park, N.Y.) 20020501 |
| Combined-modality therapy for rectal cancer using irinotecan. | Oncology (Williston Park, N.Y.) 20020501 |
| Preoperative chemoradiation for locally advanced rectal cancer: emerging treatment strategies. | Oncology (Williston Park, N.Y.) 20020501 |
| Future directions in adjuvant therapy for rectal cancer. | Oncology (Williston Park, N.Y.) 20020501 |
| Irinotecan/5-fluorouracil/leucovorin in advanced colorectal cancer: Oncologic Drugs Advisory committee summary. | Clinical colorectal cancer 20020501 |
| Postmarketing re-evaluation of irinotecan plus 5-fluorouracil/leucovorin for first-line treatment of metastatic colorectal cancer. | Clinical colorectal cancer 20020501 |
| Lessons learned from the Saltz and Mayo Clinic regimens. | Clinical colorectal cancer 20020501 |
| Chemoradiation with novel agents for rectal cancer. | Clinical colorectal cancer 20020501 |
| The role of docetaxel in nonplatinum-based combination chemotherapy for non-small-cell lung cancer. | Clinical lung cancer 20020501 |
| How to calculate the dose of chemotherapy. | British journal of cancer 20020422 |
| Phase II trial of irinotecan in combination with amifostine in patients with advanced colorectal carcinoma. | Cancer 20020415 |
| Impact of the oxaliplatin-5 fluorouracil-folinic acid combination on respective intracellular determinants of drug activity. | British journal of cancer 20020408 |
| Antisense anti-MDM2 mixed-backbone oligonucleotides enhance therapeutic efficacy of topoisomerase I inhibitor irinotecan in nude mice bearing human cancer xenografts: In vivo activity and mechanisms. | International journal of oncology 20020401 |
| Interaction of irinotecan (CPT-11) and its active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38) with human cytochrome P450 enzymes. | Drug metabolism and disposition: the biological fate of chemicals 20020401 |
| Induction of biphasic DNA double strand breaks and activation of multiple repair protein complexes by DNA topoisomerase I drug 7-ethyl-10-hydroxy-camptothecin. | Molecular pharmacology 20020401 |
| Determinants of the cytotoxicity of irinotecan in two human colorectal tumor cell lines. | Cancer chemotherapy and pharmacology 20020401 |
| Biliary transport of irinotecan and metabolites in normal and P-glycoprotein-deficient mice. | Cancer chemotherapy and pharmacology 20020401 |
| Phase II study of irinotecan (CPT-11) in children with high-risk malignant brain tumors: the Duke experience. | Neuro-oncology 20020401 |
| Irinotecan treatment for recurrent malignant glioma using an every-3-week regimen. | American journal of clinical oncology 20020401 |
| Lung cancer: a review. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20020401 |
| Cholinergic toxic syndrome by the anticancer drug irinotecan: acetylcholinesterase does not play a major role. | Clinical pharmacology and therapeutics 20020401 |
| The treatment of advanced colorectal cancer: where are we now and where do we go? | Best practice & research. Clinical gastroenterology 20020401 |
| [Antitumor activity of combination treatment combining gemcitabine with topotecin against human lung cancer xenografted in nude mice]. | Gan to kagaku ryoho. Cancer & chemotherapy 20020401 |
| [A case of recurrent rectal cancer responding to weekly low-dose CPT-11/isovorin/5-fluorouracil]. | Gan to kagaku ryoho. Cancer & chemotherapy 20020401 |
| Chemotherapy options for gastric cancer. | Seminars in radiation oncology 20020401 |
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| A new chemoembolization protocol in refractory liver metastasis of colorectal cancer--a feasibility study. | Onkologie 20020401 |
| Update on European adjuvant trials with irinotecan for colorectal cancer. | Oncology (Williston Park, N.Y.) 20020401 |
| Irinotecan/thalidomide in metastatic colorectal cancer. | Oncology (Williston Park, N.Y.) 20020401 |
| Capecitabine/irinotecan combination regimens in colorectal cancer. | Oncology (Williston Park, N.Y.) 20020401 |
| Irinotecan therapy for small-cell lung cancer. | Oncology (Williston Park, N.Y.) 20020401 |
| Phase I trials of pemetrexed. | Seminars in oncology 20020401 |
| Pemetrexed in patients with gastrointestinal carcinoma. | Seminars in oncology 20020401 |
| Raltitrexed: current clinical status and future directions. | Annals of oncology : official journal of the European Society for Medical Oncology 20020401 |
| Inhibition of cell growth by NB1011 requires high thymidylate synthase levels and correlates with p53, p21, bax, and GADD45 induction. | Molecular cancer therapeutics 20020401 |
| Consumption of an omega-3 fatty acids product, INCELL AAFA, reduced side-effects of CPT-11 (irinotecan) in mice. | British journal of cancer 20020318 |
| Circadian optimisation of irinotecan and oxaliplatin efficacy in mice with Glasgow osteosarcoma. | British journal of cancer 20020318 |
| Stability of irinotecan hydrochloride in aqueous solutions. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20020315 |
| DNA damage is able to induce senescence in tumor cells in vitro and in vivo. | Cancer research 20020315 |
| Phase II study of bi-weekly administration of paclitaxel and cisplatin in patients with advanced oesophageal cancer. | British journal of cancer 20020304 |
| Point mutations in the topoisomerase I gene in patients with non-small cell lung cancer treated with irinotecan. | Lung cancer (Amsterdam, Netherlands) 20020301 |
| Irinotecan plus gemcitabine induces both radiographic and CA 19-9 tumor marker responses in patients with previously untreated advanced pancreatic cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020301 |
| Combined chemotherapy trials require combined pharmacogenetic approaches. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020301 |
| Promising drug is victim of bad business. | Nature medicine 20020301 |
| Comparison of camptothecin derivatives presently in clinical trials: genotoxic potency and mitotic recombination. | Mutagenesis 20020301 |
| Fighting wars, winning battles. | Annals of surgical oncology 20020301 |
| Systemic irinotecan and regional floxuridine after hepatic cytoreduction in 185 patients with unresectable colorectal cancer metastases. | Annals of surgical oncology 20020301 |
| Current perspectives on the clinical experience, pharmacology, and continued development of the camptothecins. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020301 |
| [A case of hepatic metastasis from rectal carcinoma successfully treated with pharmacokinetic modulating chemotherapy (PMC)-CPT-11 therapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20020301 |
| Update on pharmacogenetics in cancer chemotherapy. | European journal of cancer (Oxford, England : 1990) 20020301 |
| Estrone and 17beta-estradiol reverse breast cancer resistance protein-mediated multidrug resistance. | Japanese journal of cancer research : Gann 20020301 |
| Factors influencing the cellular accumulation of SN-38 and camptothecin. | Cancer chemotherapy and pharmacology 20020301 |
| [Initial results of randomized studies of metastatic colorectal carcinoma urge careful and controlled use of CPT-11]. | Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20020301 |
| Anaphylactic shock secondary to intravenous administration of folinic acid: a first report. | Annals of oncology : official journal of the European Society for Medical Oncology 20020301 |
| Chemotherapy regimens in advanced non-small-cell lung cancer: recent randomized trials. | Clinical lung cancer 20020301 |
| Mortality associated with irinotecan plus bolus fluorouracil/leucovorin. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020215 |
| Enhanced clearance of topoisomerase I inhibitors from human colon cancer cells by glucuronidation. | Biochemical pharmacology 20020215 |
| Preoperative induction chemotherapy with cisplatin and irinotecan for pathological N(2) non-small cell lung cancer. | British journal of cancer 20020212 |
| Human topoisomerase I inhibition: docking camptothecin and derivatives into a structure-based active site model. | Biochemistry 20020205 |
| Sphingomyelin enhances chemotherapy efficacy and increases apoptosis in human colonic tumor xenografts. | International journal of oncology 20020201 |
| Polymorphisms of UDP-glucuronosyltransferase and pharmacokinetics of irinotecan. | Therapeutic drug monitoring 20020201 |
| Nothing succeeds like failure. | Nature biotechnology 20020201 |
| Irinotecan (CPT-11) in combination with infusional 5-fluorouracil and leucovorin (de Gramont regimen) as first-line treatment in patients with advanced colorectal cancer: a multicenter phase II study. | American journal of clinical oncology 20020201 |
| Continuous administration of irinotecan by hepatic arterial infusion: a phase I and pharmacokinetic study. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020201 |
| Future treatment options with capecitabine in solid tumours. | European journal of cancer (Oxford, England : 1990) 20020201 |
| ImClone BLA is declined. | Nature biotechnology 20020201 |
| Irinotecan hydrochloride for the treatment of recurrent and refractory non-Hodgkin lymphoma: a single institution experience. | Cancer 20020201 |
| CPT-11 plus cisplatin in patients with advanced, untreated gastric or gastroesophageal junction carcinoma: results of a phase II study. | Cancer 20020201 |
| [Globalization of anti-cancer therapies]. | Gan to kagaku ryoho. Cancer & chemotherapy 20020201 |
| [Apoptosis as a measure of chemosensitivity to anti-cancer drugs in gynecological cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20020201 |
| [A case of advanced ovarian carcinosarcoma that responded remarkably to neoadjuvant chemotherapy of combined CPT-11 and CDDP]. | Gan to kagaku ryoho. Cancer & chemotherapy 20020201 |
| Recent development of anti-cancer drugs for treatment of GI malignancies in Japan. | Gan to kagaku ryoho. Cancer & chemotherapy 20020201 |
| Retrospective comparison of single-agent chemotherapy with weekly 5-fluorouracil or weekly irinotecan in previously treated patients with metastatic colorectal cancer. | Journal of chemotherapy (Florence, Italy) 20020201 |
| Weekly irinotecan in a patient with metastatic colorectal cancer on hemodialysis due to chronic renal failure. | Onkologie 20020201 |
| Gemcitabine-based combination treatment of pancreatic cancer. | Seminars in oncology 20020201 |
| Brief communication: use of the multitargeted antifolate pemetrexed (Alimta) in genitourinary cancer. | Seminars in oncology 20020201 |
| Altered irinotecan metabolism in a patient receiving phenytoin. | Anti-cancer drugs 20020201 |
| Prediction of the response of colorectal cancer to systemic therapy. | The Lancet. Oncology 20020201 |
| [Developed new agents for lung cancer]. | Nihon Geka Gakkai zasshi 20020201 |
| Thalidomide in cancer. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20020201 |
| Irinotecan for pediatric solid tumors: the Memorial Sloan-Kettering experience. | Journal of pediatric hematology/oncology 20020201 |
| Influence of phenytoin on the disposition of irinotecan: a case report. | Journal of pediatric hematology/oncology 20020201 |
| Clinical trials using irinotecan. | Journal of pediatric hematology/oncology 20020201 |
| Phase I study of irinotecan in pediatric patients with malignant solid tumors. | Journal of pediatric hematology/oncology 20020201 |
| Antitumoral effect of irinotecan (CPT-11) on an experimental model of malignant neuroectodermal tumor. | Journal of neuro-oncology 20020201 |
| A comprehensive update on the use of chemotherapy for metastatic pancreatic adenocarcinoma. | Hematology/oncology clinics of North America 20020201 |
| Adjuvant therapy of colon cancer: a review. | Clinical colorectal cancer 20020201 |
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| Infusional 5-fluorouracil, cisplatin and mitomycin C in advanced gastric cancer: a low cost effective regimen. | British journal of cancer 20020121 |
| HER-2/neu overexpression is rare in hepatocellular carcinoma and not predictive of anti-HER-2/neu regulation of cell growth and chemosensitivity. | Cancer 20020115 |
| Irinotecan plus cisplatin compared with etoposide plus cisplatin for extensive small-cell lung cancer. | The New England journal of medicine 20020110 |
| Lung cancer--time to move on from chemotherapy. | The New England journal of medicine 20020110 |
| Irinotecan dosing: does the CPT in CPT-11 stand for 'Can't Predict Toxicity'? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020101 |
| Impact of body-size measures on irinotecan clearance: alternative dosing recommendations. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020101 |
| Randomized multicenter phase II trial of oxaliplatin plus irinotecan versus raltitrexed as first-line treatment in advanced colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020101 |
| Intestinal alkalization as a possible preventive mechanism in irinotecan (CPT-11)-induced diarrhea. | Cancer research 20020101 |
| Synergistic effects of topoisomerase I inhibitor, 7-ethyl-10-hydroxycamptothecin, and irradiation in a cisplatin-resistant human small cell lung cancer cell line. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020101 |
| O(6)-methylguanine-DNA methyltransferase (MGMT) as a determinant of resistance to camptothecin derivatives. | Japanese journal of cancer research : Gann 20020101 |
| Radiation enhancement by the combined use of topoisomerase I inhibitors, RFS-2000 or CPT-11, and topoisomerase II inhibitor etoposide in human lung cancer cells. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20020101 |
| Prediction of cell kill kinetics of anticancer agents using the collagen gel droplet embedded-culture drug sensitivity test. | Oncology reports 20020101 |
| Randomized phase II study of irinotecan plus mitomycin C vs. oxaliplatin plus mitomycin C in patients with advanced fluoropyrimidine/leucovorin-pretreated colorectal cancer. | Cancer investigation 20020101 |
| Raltitrexed (Tomudex) administration in patients with relapsed metastatic colorectal cancer after weekly irinotecan/5-Fluorouracil/Leucovorin chemotherapy. | BMC cancer 20020101 |
| Efficient induction of apoptosis by ONYX-015 adenovirus in human colon cancer cell lines regardless of p53 status. | Anti-cancer drugs 20020101 |
| Randomized clinical trials in advanced and metastatic colorectal carcinoma. | Surgical oncology clinics of North America 20020101 |
| Thalidomide in cancer treatment: a potential role in the elderly? | Drugs & aging 20020101 |
| Chronotherapy of colorectal cancer. | Chronobiology international 20020101 |
| Third Wave, Daiichi to develop personalized cancer treatment. | Expert review of molecular diagnostics 20020101 |
| Schedule-selective biochemical modulation of 5-fluorouracil in advanced colorectal cancer--a phase II study. | BMC cancer 20020101 |
| UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity. | The pharmacogenomics journal 20020101 |
| Neoadjuvant chemotherapy with CPT-11 and cisplatin downstages locally advanced gastric cancer. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20020101 |
| Adjuvant and neoadjuvant radiotherapy and concurrent radiochemotherapy for rectal cancer. | Pathology oncology research : POR 20020101 |
| Salvage chemotherapy with CPT-11 for recurrent glioblastoma multiforme. | Journal of neuro-oncology 20020101 |
| New therapeutic options in colon cancer: focus on oxaliplatin. | Clinical journal of oncology nursing 20020101 |
| An HIV treatment the world may never see. | Positively aware : the monthly journal of the Test Positive Aware Network 20020101 |
| In vitro schedule-dependent interaction between irinotecan and vinorelbine in NCI H460 non-small cell lung cancer cell line. | Anticancer research 20020101 |
| Antisense anti-MDM2 oligonucleotides as a novel approach to the treatment of glioblastoma multiforme. | Anticancer research 20020101 |
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| Is there a preferred combination chemotherapy regimen for metastastic non-small cell lung cancer? | The oncologist 20020101 |
| A phase II study of irinotecan alternated with a weekly schedule of high-dose leucovorin and 48-hour 5-fluorouracil infusion in patients with metastatic colorectal cancer. | Oncology 20020101 |
| Outpatient therapy with irinotecan and low-dose cisplatin for metastatic colorectal cancer resistant to 5-fluorouracil. | Oncology reports 20020101 |
| Neoadjuvant chemotherapy of irinotecan, 5-fluorouracil and leucovorin in patients with advanced rectal cancer. Report of two cases. | Hepato-gastroenterology 20020101 |
| Effect of irinotecan on the phenotype of peripheral blood leukocyte populations in patients with metastatic colorectal cancer. | Hepato-gastroenterology 20020101 |
| A dose-escalation study of irinotecan (CPT-11) in combination with gemcitabine in patients with advanced non-small cell lung cancer previously treated with a cisplatin-based front line chemotherapy. | Anticancer research 20020101 |
| Adjuvant therapy for colorectal carcinoma. | Anticancer research 20020101 |
| Irinotecan (CPT-11) and cisplatin as first-line chemotherapy for advanced ovarian cancer. | Oncology 20020101 |
| Multicenter phase I study of irinotecan plus raltitrexed in patients with 5-fluorouracil-refractory advanced colorectal cancer. | Oncology 20020101 |
| Intermittent, repetitive administrations of irinotecan (CPT-11) reduces its side-effects. | Cancer detection and prevention 20020101 |
| Camptothecins: a review of their chemotherapeutic potential. | Drugs 20020101 |
| Current status and perspectives in the development of camptothecins. | Current pharmaceutical design 20020101 |
| Combined irinotecan, oxaliplatin and 5-fluorouracil in patients with advanced colorectal cancer. a feasibility pilot study. | Oncology 20020101 |
| Augmented anti-metastatic efficacy of a selective matrix metalloproteinase inhibitor, MMI-166, in combination with CPT-11. | Clinical & experimental metastasis 20020101 |
| In vivo advantage of combined administration with CPT-11 and 5-fluorouracil in rats. | Journal of experimental therapeutics & oncology 20020101 |
| Chemotherapy in colorectal cancer: new options and new challenges. | British medical bulletin 20020101 |
| [Raltitrexed and oxaliplatin in colorectal cancer: in vitro and in vivo study of a synergistic cytostatic combination]. | Acta medica Austriaca 20020101 |
| CDK inhibitors: cell cycle arrest versus apoptosis. | Cell cycle (Georgetown, Tex.) 20020101 |
| The search for enhanced therapeutic index in breast cancer: targeting the tumor and modulation of enzyme expression. | Cancer investigation 20020101 |
| New chemotherapeutic agents: update of major chemoradiation trials in solid tumors. | Oncology 20020101 |
| Molecular and cellular characterization of imexon-resistant RPMI8226/I myeloma cells. | Molecular cancer therapeutics 20020101 |
| Irinotecan plus low-dose cisplatin for alpha-fetoprotein-producing gastric carcinoma with multiple liver metastases: report of two cases. | Surgery today 20020101 |
| Irinotecan and vinorelbine in patients with non-small cell lung cancer previously treated with platinum-based chemotherapy. A phase II study of the Hellenic Cooperative Oncology Group. | Anticancer research 20020101 |
| Efficacy of prophylactic anti-diarrhoeal treatment in patients receiving Campto for advanced colorectal cancer. | Anticancer research 20020101 |
| Topoisomerase inhibitor-induced apoptosis accompanied by down-regulation of Bcl-2 in human lung cancer cells. | Anticancer research 20020101 |
| Phase I dose escalation trial of weekly docetaxel plus irinotecan in patients with advanced cancer. | Cancer biology & therapy 20020101 |
| Topoisomerase I interactive agents. | Cancer chemotherapy and biological response modifiers 20020101 |
| Influence of multiple dose activated charcoal on the disposition kinetics of irinotecan in rats. | Drug metabolism and drug interactions 20020101 |
| The role of chemotherapy in the current treatment of gastric cancer. | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20020101 |
| CPT-11 for bile-duct and gallbladder carcinoma: a phase II North Central Cancer Treatment Group (NCCTG) study. | International journal of gastrointestinal cancer 20020101 |
| A phase II trial of docetaxel and CPT-11 in patients with metastatic adenocarcinoma of the esophagus, gastroesophageal junction, and gastric cardia. | International journal of gastrointestinal cancer 20020101 |
| The potential for an interaction between MRP2 (ABCC2) and various therapeutic agents: probenecid as a candidate inhibitor of the biliary excretion of irinotecan metabolites. | Drug metabolism and pharmacokinetics 20020101 |
| Does ABCG2 need a heterodimer partner? Expression and functional evaluation of ABCG2 (Arg 482)*. | Drug metabolism and pharmacokinetics 20020101 |
| Three novel single nucleotide polymorphisms in UGT1A10. | Drug metabolism and pharmacokinetics 20020101 |
| Phase I trial of weekly irinotecan combined with UFT as second-line treatment for advanced colorectal cancer. | European journal of cancer (Oxford, England : 1990) 20011201 |
| Doxorubicin-induced DNA intercalation and scavenging by nuclear glutathione S-transferase pi. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011201 |
| ERCC1 and thymidylate synthase mRNA levels predict survival for colorectal cancer patients receiving combination oxaliplatin and fluorouracil chemotherapy. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20011201 |
| Oxaliplatin: available data in non-colorectal gastrointestinal malignancies. | Critical reviews in oncology/hematology 20011201 |
| Acetylcholinesterase blockade does not account for the adverse cardiovascular effects of the antitumor drug irinotecan: a preclinical study. | Toxicology and applied pharmacology 20011201 |
| Topoisomerase I inhibitors combination chemotherapy in non-small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20011201 |
| Cisplatin and irinotecan (CPT-11) as second-line treatment in patients with advanced non-small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20011201 |
| Radiosensitization with chemotherapeutic agents. | Lung cancer (Amsterdam, Netherlands) 20011201 |
| CPT-11 may provide therapeutic efficacy for esophageal squamous cell cancer and the effects correlate with the level of DNA topoisomerase I protein. | Japanese journal of cancer research : Gann 20011201 |
| Augmentation of apoptosis and tumor regression by flavopiridol in the presence of CPT-11 in Hct116 colon cancer monolayers and xenografts. | Clinical cancer research : an official journal of the American Association for Cancer Research 20011201 |
| [Phase I study with irinotecan hydrochloride (CPT-11) for advanced neuroblastoma]. | Gan to kagaku ryoho. Cancer & chemotherapy 20011201 |
| [Chemotherapy of colorectal carcinoma]. | Der Internist 20011201 |
| Phase I/II and pharmacologic study of irinotecan and carboplatin for patients with lung cancer. | Cancer chemotherapy and pharmacology 20011201 |
| Pancreatic cancer: the evolving role of systemic therapy. | Expert opinion on pharmacotherapy 20011201 |
| Phase I-II study of irinotecan combined with mitomycin-C in patients with advanced gastric cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20011201 |
| Metastatic colorectal cancer. | Current treatment options in oncology 20011201 |
| Quantitation of camptothecin and related compounds. | Journal of chromatography. B, Biomedical sciences and applications 20011125 |
| Analytical approaches for traditional chinese medicines exhibiting antineoplastic activity. | Journal of chromatography. B, Biomedical sciences and applications 20011125 |
| Randomized multicenter phase II study comparing a combination of fluorouracil and folinic acid and alternating irinotecan and oxaliplatin with oxaliplatin and irinotecan in fluorouracil-pretreated metastatic colorectal cancer patients. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20011115 |
| Transport of 7-ethyl-10-hydroxycamptothecin (SN-38) by breast cancer resistance protein ABCG2 in human lung cancer cells. | Biochemical and biophysical research communications 20011109 |
| A new metabolite of irinotecan in which formation is mediated by human hepatic cytochrome P-450 3A4. | Drug metabolism and disposition: the biological fate of chemicals 20011101 |
| Unique action determinants of double acting topoisomerase inhibitor, TAS-103. | International journal of oncology 20011101 |
| Activation of nuclear factor kappaB through the IKK complex by the topoisomerase poisons SN38 and doxorubicin: a brake to apoptosis in HeLa human carcinoma cells. | Cancer research 20011101 |
| Characterization of a thymidylate synthase (TS)-inducible cell line: a model system for studying sensitivity to TS- and non-TS-targeted chemotherapies. | Clinical cancer research : an official journal of the American Association for Cancer Research 20011101 |
| Paclitaxel and SN-38 overcome cisplatin resistance of ovarian cancer cell lines by down-regulating the influx and efflux system of cisplatin. | Japanese journal of cancer research : Gann 20011101 |
| Oxaliplatin and protracted venous infusion of 5-fluorouracil in patients with advanced or relapsed 5-fluorouracil pretreated colorectal cancer. | British journal of cancer 20011101 |
| [A case of lung metastasis from colon cancer treated successfully with combined chemotherapy of CPT-11 and 5'-DFUR]. | Gan to kagaku ryoho. Cancer & chemotherapy 20011101 |
| Treatment of human colon carcinoma cell lines with anti-neoplastic agents enhances their lytic sensitivity to antigen-specific CD8+ cytotoxic T lymphocytes. | Cancer immunology, immunotherapy : CII 20011101 |
| Toxicity of irinotecan in patients with colorectal cancer. | The New England journal of medicine 20011101 |
| A phase II study of irinotecan with 5-fluorouracil and leucovorin in patients with previously untreated gastric adenocarcinoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20011101 |
| Phase I dose-finding and pharmacokinetic trial of irinotecan (CPT-11) administered every two weeks. | Annals of oncology : official journal of the European Society for Medical Oncology 20011101 |
| [New therapeutic approaches in non-small-cell lung carcinoma (NSCLC), stages IV]. | Revue de pneumologie clinique 20011101 |
| Perspectives in colorectal cancer meeting. Miami, Florida. September 28-29, 2001. | Clinical colorectal cancer 20011101 |
| Capecitabine combinations in the treatment of advanced colorectal cancer. | Clinical colorectal cancer 20011101 |
| Irinotecan plus oxaliplatin: a promising combination for advanced colorectal cancer. | Clinical colorectal cancer 20011101 |
| A lipophilic vasoactive intestinal peptide analog enhances the antiproliferative effect of chemotherapeutic agents on cancer cell lines. | Cancer 20011015 |
| Phase I clinical and pharmacogenetic trial of irinotecan and raltitrexed administered every 21 days to patients with cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20011015 |
| Downregulation of topoisomerase I in differentiating human intestinal epithelial cells. | International journal of cancer 20011015 |
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| High-performance liquid chromatographic technique for the simultaneous determination of lactone and hydroxy acid forms of camptothecin and SN-38 in tissue culture media and cancer cells. | Analytical biochemistry 20011001 |
| Non-operative management of the primary tumour in patients with incurable stage IV colorectal cancer. | The British journal of surgery 20011001 |
| Combination of oxaliplatin and irinotecan on human colon cancer cell lines: activity in vitro and in vivo. | Anti-cancer drugs 20011001 |
| [Standard therapy of CPT-11 for colorectal cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20011001 |
| Human liver UDP-glucuronosyltransferase isoforms involved in the glucuronidation of 7-ethyl-10-hydroxycamptothecin. | Xenobiotica; the fate of foreign compounds in biological systems 20011001 |
| [Pharmacokinetic study of the intraperitoneal administration of CPT-11 for patients with peritoneal seedings of gastric and colonic cancers]. | Gan to kagaku ryoho. Cancer & chemotherapy 20011001 |
| [Sigmoid colon cancer with multiple liver metastasis (H3) effectively treated with CPT-11 and DSM (degradable starch microsphere) HAI therapy and intensive high dosage 5-FU HAI therapy--a case report]. | Gan to kagaku ryoho. Cancer & chemotherapy 20011001 |
| [Four cases of multiple liver metastasis of colorectal cancer treated with hepatic resection after chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20011001 |
| [Two cases of multiple liver metastases of colon cancer with systemic irinotecan and hepatic arterial injection of 5-FU]. | Gan to kagaku ryoho. Cancer & chemotherapy 20011001 |
| Irinotecan-induced dysarthria. | Journal of the National Cancer Institute 20010919 |
| Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells. | Cancer research 20010915 |
| Mortality associated with irinotecan plus bolus fluorouracil/leucovorin: summary findings of an independent panel. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010915 |
| [Recent aspects of palliative treatment of metastasized colorectal carcinoma]. | Medizinische Klinik (Munich, Germany : 1983) 20010915 |
| Cryptophycins: a novel class of potent antimitotic antitumor depsipeptides. | Current pharmaceutical design 20010901 |
| Apoptosis induced by the homocamptothecin anticancer drug BN80915 in HL-60 cells. | Molecular pharmacology 20010901 |
| Irinotecan and oxaliplatin: an overview of the novel chemotherapeutic options for the treatment of advanced colorectal cancer. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20010901 |
| Body-surface area-based dosing does not increase accuracy of predicting cisplatin exposure. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010901 |
| Comment on a published paper. The adverse cholinergic effects of the chemotherapeutic agent irinotecan (CPT-11) were unlikely to be mediated by the inhibition of acetylcholinesterase (AChE). | British journal of pharmacology 20010901 |
| Trends and perspectives in multimodality therapy of locoregionally advanced non-small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20010901 |
| Chemotherapy as treatment of primary and recurrent small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20010901 |
| [Levofolinate and fluorouracil combination therapy]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20010901 |
| [A case of esophageal small-cell carcinoma responding to chemotherapy with CTP-11]. | Gan to kagaku ryoho. Cancer & chemotherapy 20010901 |
| Limited sampling models for CPT-11, SN-38, and SN-38 glucuronide. | Cancer chemotherapy and pharmacology 20010901 |
| Multicenter phase II trial of dose-fractionated irinotecan in patients with advanced colorectal cancer failing oxaliplatin-based first-line combination chemotherapy. | Annals of oncology : official journal of the European Society for Medical Oncology 20010901 |
| The role of topoisomerase I inhibitor in cisplatin-resistant ovarian cancer. | Human cell 20010901 |
| Structural constraints affect the metabolism of 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11) by carboxylesterases. | Molecular pharmacology 20010801 |
| Phase I clinical trial of weekly combined topotecan and irinotecan. | American journal of clinical oncology 20010801 |
| Sequence effect of irinotecan and fluorouracil treatment on pharmacokinetics and toxicity in chemotherapy-naive metastatic colorectal cancer patients. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010801 |
| Two unusual sites of colon cancer metastases and a rare thyroid lymphoma. Case 2. Chemotherapy-responsive right artial metastasis from colon carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010801 |
| Toxicity of irinotecan (CPT-11) and hepato-renal dysfunction. | Anti-cancer drugs 20010801 |
| Clinical pharmacokinetics and metabolism of irinotecan (CPT-11). | Clinical cancer research : an official journal of the American Association for Cancer Research 20010801 |
| Marked antitumor activity of a new potent acronycine derivative in orthotopic models of human solid tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20010801 |
| High-performance liquid chromatographic assay for glucuronidation activity of 7-ethyl-10-hydroxycamptothecin (SN-38), the active metabolite of irinotecan (CPT-11), in human liver microsomes. | Biomedical chromatography : BMC 20010801 |
| New options for outpatient chemotherapy--the role of oral fluoropyrimidines. | Cancer treatment reviews 20010801 |
| Temozolomide in combination with other cytotoxic agents. | Seminars in oncology 20010801 |
| Dose escalation study of irinotecan combined with carboplatin for advanced non-small-cell lung cancer. | Cancer chemotherapy and pharmacology 20010801 |
| [Oxaliplatin: a first DACH-platinum in oncology]. | Bulletin du cancer 20010801 |
| [Oxaliplatin in combination with 5-fluoro-uracil and folinic acid as treatment of metastatic colorectal cancer]. | Bulletin du cancer 20010801 |
| [Oxaliplatin in combination with non fluoropyrimidine drugs in colorectal cancer]. | Bulletin du cancer 20010801 |
| Clinical effect of irinotecan in advanced and metastatic breast cancer patients previously treated with doxorubicin- and docetaxel-containing regimens. | Japanese journal of clinical oncology 20010801 |
| Chemotherapy with irinotecan (CPT-11), a topoisomerase-I inhibitor, for refractory and relapsed non-Hodgkin's lymphoma. | Leukemia & lymphoma 20010801 |
| Natural products in anticancer therapy. | Current opinion in pharmacology 20010801 |
| Multiple drug resistance phenotype of human endothelial cells induced by vascular endothelial growth factor 165. | Acta pharmacologica Sinica 20010801 |
| Cellular, pharmacokinetic, and pharmacodynamic aspects of response to camptothecins: can we improve it? | Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20010801 |
| Irinotecan in the treatment of small cell lung cancer. | Expert review of anticancer therapy 20010801 |
| Management of small cell lung cancer. | Expert review of anticancer therapy 20010801 |
| Therapeutic advances in the management of metastatic colorectal cancer. | Expert review of anticancer therapy 20010801 |
| Recommendation for irinotecan, 5-fluorouracil, and leucovorin as first-line therapy for colorectal cancer. | Clinical colorectal cancer 20010801 |
| Irinotecan/5-FU/leucovorin, oxaliplatin/5-FU/leucovorin, and oxaliplatin/irinotecan are each effective in the treatment of 5-FU-resistant advanced colorectal cancer. | Clinical colorectal cancer 20010801 |
| Review of the role of CPT-11 in the treatment of colorectal cancer. | Clinical colorectal cancer 20010801 |
| Recommendation for caution with irinotecan, fluorouracil, and leucovorin for colorectal cancer. | The New England journal of medicine 20010712 |
| Recommendation for caution with irinotecan, fluorouracil, and leucovorin for colorectal cancer. | The New England journal of medicine 20010712 |
| New chemotherapy approaches in colorectal cancer. | Current opinion in oncology 20010701 |
| Sensitization of human tumor cells to CPT-11 via adenoviral-mediated delivery of a rabbit liver carboxylesterase. | Cancer research 20010701 |
| A virus-directed enzyme prodrug therapy approach to purging neuroblastoma cells from hematopoietic cells using adenovirus encoding rabbit carboxylesterase and CPT-11. | Cancer research 20010701 |
| Phase I study of irinotecan and cisplatin with concurrent split-course radiotherapy in unresectable and locally advanced non-small cell lung cancer. | European journal of cancer (Oxford, England : 1990) 20010701 |
| In vivo antitumour efficacy of MGI-114 (6-hydroxymethylacylfulvene, HMAF) in various human tumour xenograft models including several lung and gastric tumours. | European journal of cancer (Oxford, England : 1990) 20010701 |
| Fractionated administration of irinotecan and cisplatin for treatment of non-small-cell lung cancer: a phase II study of Okayama Lung Cancer Study Group. | British journal of cancer 20010701 |
| Researchers urge caution with standard regimen for metastatic colorectal cancer. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20010701 |
| [Usefulness of chemotherapy with CPT-11 in clinic for three colorectal cancer in terminal stage]. | Gan to kagaku ryoho. Cancer & chemotherapy 20010701 |
| Therapeutic activity of 7-[(2-trimethylsilyl)ethyl)]-20 (S)-camptothecin against central nervous system tumor-derived xenografts in athymic mice. | Cancer chemotherapy and pharmacology 20010701 |
| [Adjuvant chemotherapy in liver malignancy for improving operability]. | Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 20010701 |
| The emerging world role of irinotecan in lung cancer. | Oncology (Williston Park, N.Y.) 20010701 |
| Irinotecan and radiation in combined-modality therapy for solid tumors. | Oncology (Williston Park, N.Y.) 20010701 |
| Rationale for non-platinum chemotherapy in advanced NSCLC. | Oncology (Williston Park, N.Y.) 20010701 |
| Topoisomerase I inhibitors in the treatment of head and neck cancer. | Oncology (Williston Park, N.Y.) 20010701 |
| Irinotecan in relapsed or refractory non-Hodgkin's lymphoma. | Oncology (Williston Park, N.Y.) 20010701 |
| Role of topoisomerase I inhibitors in small-cell lung cancer. | Oncology (Williston Park, N.Y.) 20010701 |
| Recent advances in the chemotherapy of non-small cell lung cancer. | Japanese journal of clinical oncology 20010701 |
| Combination therapy with irinotecan (CPT-11), mitoxantrone, and dexamethasone in relapsed or refractory non-Hodgkin's lymphoma: a pilot study. | Annals of hematology 20010701 |
| Hepatic extraction, metabolism, and biliary excretion of irinotecan in the isolated perfused rat liver. | Journal of pharmaceutical sciences 20010601 |
| Active transepithelial transport of irinotecan (CPT-11) and its metabolites by human intestinal Caco-2 cells. | Anti-cancer drugs 20010601 |
| Phase I-II study of irinotecan in combination with mitomycin C in patients with advanced gastrointestinal cancer. | American journal of clinical oncology 20010601 |
| Control of irinotecan-induced diarrhea by octreotide after loperamide failure. | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20010601 |
| [A case of advanced gastric cancer treated with neoadjuvant chemotherapy of low-dose CPT-11 + CDDP]. | Gan to kagaku ryoho. Cancer & chemotherapy 20010601 |
| [A case of papillary adenocarcinoma of the ovary that responded favorably to irinotecan hydrochloride and cisplatin after the administration of paclitaxel and carboplatin]. | Gan to kagaku ryoho. Cancer & chemotherapy 20010601 |
| Non-platinum based combination chemotherapy: phase I and II trials of docetaxel plus gemcitabine, vinorelbine, or irinotecan. | Seminars in oncology 20010601 |
| [Irinotecan plus fluorouracil and folinic acid in metastatic colorectal cancer]. | Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20010601 |
| Treatment of metastatic pancreatic adenocarcinoma: a comprehensive review. | The Surgical clinics of North America 20010601 |
| Therapy for regionally unresectable pancreatic cancer. | The Surgical clinics of North America 20010601 |
| Excretion into gastrointestinal tract of irinotecan lactone and carboxylate forms and their pharmacodynamics in rodents. | Pharmaceutical research 20010601 |
| Beyond pancreatic cancer: irinotecan and gemcitabine in solid tumors and hematologic malignancies. | Seminars in oncology 20010601 |
| In vitro schedule dependency in the treatment of topoisomerase I and II inhibitor. | Osaka city medical journal 20010601 |
| Cellular, pharmacokinetic, and pharmacodynamic aspects of response to camptothecins: can we improve it? | Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20010601 |
| Innovative treatments for non-small cell lung cancer. | Expert opinion on investigational drugs 20010601 |
| Phase I study of hepatic arterial infusion of floxuridine and dexamethasone with systemic irinotecan for unresectable hepatic metastases from colorectal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010515 |
| Potentiation of antitumor activity of irinotecan by chemically modified oligonucleotides. | International journal of oncology 20010501 |
| Integrating the oral fluoropyrimidines into the management of advanced colorectal cancer. | European journal of cancer (Oxford, England : 1990) 20010501 |
| Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: implications for systemic nuclear factor-kappaB inhibition. | Cancer research 20010501 |
| Impact on survival following successful neoadjuvant chemotherapy and radical surgery for Stage IIb bulky and Stage IIIb cervical cancer. | Gynecologic oncology 20010501 |
| Modulation of irinotecan-induced diarrhea by cotreatment with neomycin in cancer patients. | Clinical cancer research : an official journal of the American Association for Cancer Research 20010501 |
| CPT-11 alters the circadian rhythm of dihydropyrimidine dehydrogenase mRNA in mouse liver. | Japanese journal of cancer research : Gann 20010501 |
| [Platinum compounds in cancer therapy--past, present, and future]. | Gan to kagaku ryoho. Cancer & chemotherapy 20010501 |
| [A modified administrated schedule for combination therapy with irinotecan and cisplatin as a neoadjuvant chemotherapy in locally advanced cervical cancer--a report of 2 cases as a pilot study]. | Gan to kagaku ryoho. Cancer & chemotherapy 20010501 |
| Preliminary study of fortnightly irinotecan hydrochloride plus cisplatin therapy in patients with advanced gastric and colorectal cancer. | Cancer chemotherapy and pharmacology 20010501 |
| Phase I trial of gemcitabine and CPT-11 given weekly for four weeks every six weeks. | Annals of oncology : official journal of the European Society for Medical Oncology 20010501 |
| Second-line treatment with oxaliplatin + raltitrexed in patients with advanced colorectal cancer failing fluoropyrimidine/leucovorin-based chemotherapy. | Annals of oncology : official journal of the European Society for Medical Oncology 20010501 |
| Rhabdomyosarcoma and undifferentiated sarcoma in the first two decades of life: a selective review of intergroup rhabdomyosarcoma study group experience and rationale for Intergroup Rhabdomyosarcoma Study V. | Journal of pediatric hematology/oncology 20010501 |
| New therapies, new directions: advances in the systemic treatment of metastatic colorectal cancer. | The Lancet. Oncology 20010501 |
| 25th European Society for Medical Oncology Congress. Hamburg, Germany. October 13-17, 2000. | Clinical colorectal cancer 20010501 |
| Advances in the treatment of metastatic colorectal cancer. | Clinical colorectal cancer 20010501 |
| Systemic irinotecan or regional floxuridine chemotherapy prolongs survival after hepatic cryosurgery in patients with metastatic colon cancer refractory to 5-fluorouracil. | Clinical colorectal cancer 20010501 |
| Role of topoisomerase I inhibitors in small-cell lung cancer. | Clinical lung cancer 20010501 |
| Irinotecan in small-cell lung cancer: current data. | Clinical lung cancer 20010501 |
| Irinotecan: future directions in small-cell lung cancer. | Clinical lung cancer 20010501 |
| Irinotecan and platinums in the treatment of non small-cell lung cancer. | Clinical lung cancer 20010501 |
| Irinotecan and taxane combinations for non small-cell lung cancer. | Clinical lung cancer 20010501 |
| Irinotecan (CPT-11) in triplet combinations in patients with advanced non small-cell lung cancer: a review and report of a phase I/II trial. | Clinical lung cancer 20010501 |
| Topoisomerase I inhibitors in the combined modality therapy of lung cancer. | Clinical lung cancer 20010501 |
| Prevention of irinotecan (CPT-11)-induced diarrhea by oral alkalization combined with control of defecation in cancer patients. | International journal of cancer 20010415 |
| Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues. | Cancer research 20010415 |
| Inhibitory effect of berberine on the mediastinal lymph node metastasis produced by orthotopic implantation of Lewis lung carcinoma. | Cancer letters 20010410 |
| Pharmacogenetics of anticancer agents: lessons from amonafide and irinotecan. | Drug metabolism and disposition: the biological fate of chemicals 20010401 |
| Use of a modified ornithine decarboxylase promoter to achieve efficient c-MYC- or N-MYC-regulated protein expression. | Cancer research 20010401 |
| Circumvention of breast cancer resistance protein (BCRP)-mediated resistance to camptothecins in vitro using non-substrate drugs or the BCRP inhibitor GF120918. | Clinical cancer research : an official journal of the American Association for Cancer Research 20010401 |
| [Chemotherapy by combination of low-dose CPT-11 and PSK in an elderly man with liver metastasis from gastric cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20010401 |
| Antitumor activity of XR5944, a novel and potent topoisomerase poison. | Anti-cancer drugs 20010401 |
| Human plasma carboxylesterase and butyrylcholinesterase enzyme activity: correlations with SN-38 pharmacokinetics during a prolonged infusion of irinotecan. | Cancer chemotherapy and pharmacology 20010401 |
| The role of irinotecan and oxaliplatin in the treatment of advanced colorectal cancer. | Oncology (Williston Park, N.Y.) 20010401 |
| A phase II trial of irinotecan (CPT-11) for unresectable biliary tree carcinoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20010401 |
| Safe administration of irinotecan, oxaliplatin and raltitrexed in a DPD-deficient patient with metastatic colon cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20010401 |
| 26S proteasome inhibition induces apoptosis and limits growth of human pancreatic cancer. | Journal of cellular biochemistry 20010401 |
| [Chemotherapy of irinotecan (CPT-11) combined with cisplatin in patients with advanced gastric cancer]. | Nihon rinsho. Japanese journal of clinical medicine 20010401 |
| [Irinotecan (CPT-11) therapy for advanced gastric cancer]. | Nihon rinsho. Japanese journal of clinical medicine 20010401 |
| [Home chemotherapy and/or outpatient chemotherapy for patient with advanced gastric cancer]. | Nihon rinsho. Japanese journal of clinical medicine 20010401 |
| [New chemotherapies for colorectal cancer treatment]. | Gastroenterologie clinique et biologique 20010401 |
| Irinotecan as first-line treatment of colorectal cancer: new indication. A modest advantage. | Prescrire international 20010401 |
| [Chemotherapy of colonic carcinoma in the year 2001]. | Praxis 20010322 |
| Roles of NF-kappaB and 26 S proteasome in apoptotic cell death induced by topoisomerase I and II poisons in human nonsmall cell lung carcinoma. | The Journal of biological chemistry 20010316 |
| Determinants of prognosis and response to therapy in colorectal cancer. | Current oncology reports 20010301 |
| Oxaliplatin: a new agent for colorectal cancer. | Current oncology reports 20010301 |
| Topoisomerase I targeting agents in small-cell lung cancer. | Current oncology reports 20010301 |
| Optimizing chemoradiation therapy approaches to unresectable stage III non--small cell lung cancer. | Current opinion in oncology 20010301 |
| Irinotecan in the treatment of colorectal cancer: clinical overview. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010301 |
| [A case of AFP-producing gastric cancer responding to low-dose CPT-11 and low-dose cisplatin combination chemotherapy]. | Gan to kagaku ryoho. Cancer & chemotherapy 20010301 |
| Cisplatin and irinotecan in upper gastrointestinal malignancies. | Oncology (Williston Park, N.Y.) 20010301 |
| Irinotecan/gemcitabine combination chemotherapy in pancreatic cancer. | Oncology (Williston Park, N.Y.) 20010301 |
| Irinotecan plus cisplatin in advanced gastric or gastroesophageal junction carcinoma. | Oncology (Williston Park, N.Y.) 20010301 |
| The Intergroup Rhabdomyosarcoma Study Group (IRSG): Major Lessons From the IRS-I Through IRS-IV Studies as Background for the Current IRS-V Treatment Protocols. | Sarcoma 20010301 |
| Effect of bile acids on the uptake of irinotecan and its active metabolite, SN-38, by intestinal cells. | Biochimica et biophysica acta 20010216 |
| Phase I trial of the combination of irinotecan, paclitaxel, and carboplatin in patients with advanced non-small-cell lung cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010215 |
| Phase II study of irinotecan as first-line chemotherapy for patients with advanced colorectal carcinoma. | Cancer 20010215 |
| Irinotecan and chronomodulated infusion of 5-fluorouracil and folinic acid in the treatment of patients with advanced colorectal carcinoma: a phase I study. | Cancer 20010215 |
| Breast cancer resistance protein directly confers SN-38 resistance of lung cancer cells. | Biochemical and biophysical research communications 20010209 |
| Combination chemotherapy in patients with malignant pleural effusions from non-small cell lung cancer : cisplatin, ifosfamide, and irinotecan with recombinant human granulocyte colony-stimulating factor support. | Chest 20010201 |
| Ternary combination of irinotecan, fluorouracil-folinic acid and oxaliplatin: results on human colon cancer cell lines. | British journal of cancer 20010201 |
| Different susceptibilities of postmitotic checkpoint-proficient and -deficient Balb / 3T3 cells to ICRF-193, a catalytic inhibitor of DNA topoisomerase II. | Japanese journal of cancer research : Gann 20010201 |
| Prospective phase II trial of iriontecan, 5-fluorouracil, and leucovorin in combination as salvage therapy for advanced colorectal cancer. | American journal of clinical oncology 20010201 |
| [Weekly low dose CPT-11 for multiple lung metastases of colon cancer on an out-patient treatment: a case report]. | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20010201 |
| Adjuvant therapy of colon cancer. | Seminars in oncology 20010201 |
| Modulation of camptothecin analogs in the treatment of cancer: a review. | Anti-cancer drugs 20010201 |
| North Central Cancer Treatment Group--Mayo Clinic trials in colon cancer. | Seminars in oncology 20010201 |
| [Medical treatment of pulmonary neoplasms]. | Recenti progressi in medicina 20010201 |
| The current status of docetaxel for advanced non-small cell lung cancer. | Anti-cancer drugs 20010201 |
| [Chemotherapy of colorectal cancer--which therapy is justified for elderly patients?]. | Onkologie 20010201 |
| A novel B-ring modified homocamptothecin, 12-Cl-hCPT, showing antiproliferative and topoisomerase I inhibitory activities superior to SN-38. | Anti-cancer drug design 20010201 |
| Irinotecan/cisplatin versus vindesine/cisplatin versus irinotecan alone in advanced non-small-cell lung cancer. | Clinical lung cancer 20010201 |
| Repression of cyclin B1 expression after treatment with adriamycin, but not cisplatin in human lung cancer A549 cells. | Biochemical and biophysical research communications 20010126 |
| Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. | The New England journal of medicine 20010125 |
| Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. | The New England journal of medicine 20010125 |
| Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. | The New England journal of medicine 20010125 |
| Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. | The New England journal of medicine 20010125 |
| Glucagon-like peptide (GLP)-2 reduces chemotherapy-associated mortality and enhances cell survival in cells expressing a transfected GLP-2 receptor. | Cancer research 20010115 |
| The HER tyrosine kinase inhibitor CI1033 enhances cytotoxicity of 7-ethyl-10-hydroxycamptothecin and topotecan by inhibiting breast cancer resistance protein-mediated drug efflux. | Cancer research 20010115 |
| The changing face of chemotherapy in colorectal cancer. | British journal of cancer 20010101 |
| A phase II study of irinotecan in patients with advanced hepatocellular carcinoma. | Cancer 20010101 |
| Gemcitabine: progress in the treatment of pancreatic cancer. | Oncology 20010101 |
| Characterization of a novel mechanism accounting for the adverse cholinergic effects of the anticancer drug irinotecan. | British journal of pharmacology 20010101 |
| Irinotecan: a new agent comes of age. | The oncologist 20010101 |
| Irinotecan (CPT-11): recent developments and future directions--colorectal cancer and beyond. | The oncologist 20010101 |
| Irinotecan plus fluorouracil/leucovorin for metastatic colorectal cancer: a new survival standard. | The oncologist 20010101 |
| Influence of cytokines, monoclonal antibodies and chemotherapeutic drugs on epithelial cell adhesion molecule (EpCAM) and LewisY antigen expression. | Clinical and experimental immunology 20010101 |
| [Refinement and role of the diagnosis of Gilbert disease with molecular biology]. | Annales de biologie clinique 20010101 |
| [A case of small cell carcinoma of esophagus successfully treated by chemotherapy with CPT-11 and CDDP]. | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20010101 |
| Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20010101 |
| In vitro synergistic interactions between the cisplatin analogue nedaplatin and the DNA topoisomerase I inhibitor irinotecan and the mechanism of this interaction. | Clinical cancer research : an official journal of the American Association for Cancer Research 20010101 |
| A phase I study of irinotecan in pediatric patients: a pediatric oncology group study. | Clinical cancer research : an official journal of the American Association for Cancer Research 20010101 |
| Weekly irinotecan and cisplatin in advanced non-small cell lung cancer: a multicenter phase II study. | Clinical cancer research : an official journal of the American Association for Cancer Research 20010101 |
| Oral fluoropyrimidine-based combination therapy in gastrointestinal cancer. | Oncology (Williston Park, N.Y.) 20010101 |
| Irinotecan in small-cell lung cancer: the US experience. | Oncology (Williston Park, N.Y.) 20010101 |
| Establishment of the standard regimen for non-small-cell lung cancer in Japan. | Oncology (Williston Park, N.Y.) 20010101 |
| Treatment of non-small-cell lung cancer in North America: the emerging role of irinotecan. | Oncology (Williston Park, N.Y.) 20010101 |
| Rationale and dose-finding studies of the combination of irinotecan and a taxane on a weekly schedule. | Oncology (Williston Park, N.Y.) 20010101 |
| Irinotecan in combined-modality therapy for locally advanced non-small-cell lung cancer. | Oncology (Williston Park, N.Y.) 20010101 |
| Docetaxel followed by gemcitabine and irinotecan in solid tumors. | Oncology (Williston Park, N.Y.) 20010101 |
| Irinotecan: summary and future directions. | Oncology (Williston Park, N.Y.) 20010101 |
| Current status of irinotecan in lung cancer. | Oncology (Williston Park, N.Y.) 20010101 |
| New state of the art in small-cell lung cancer. | Oncology (Williston Park, N.Y.) 20010101 |
| Chemoradiation in locally advanced non-small cell lung cancer. | Cancer treatment and research 20010101 |
| Lung cancer: therapeutic options for stage IV and recurrent NSCLC. | Cancer treatment and research 20010101 |
| Treatment of extensive stage small cell lung cancer. | Cancer treatment and research 20010101 |
| Irinotecan and mitomycin C in 5-fluorouracil-refractory colorectal cancer patients. A phase I/II study of the Southern Italy Cooperative Oncology Group. | Oncology 20010101 |
| Perioperative radiotherapy and concurrent radiochemotherapy in rectal cancer. | Seminars in surgical oncology 20010101 |
| Factors affecting the pharmacokinetics of CPT-11: the body mass index, age and sex are independent predictors of pharmacokinetic parameters of CPT-11. | Investigational new drugs 20010101 |
| Topoisomerase I-DNA covalent complexes in human colorectal cancer xenografts with different p53 and microsatellite instability status: relation with their sensitivity to CTP-11. | Anticancer research 20010101 |
| [Irinotecan in colorectal cancer]. | Tumori 20010101 |
| [Molecular factors predictive of response to chemotherapy in advanced stages of colorectal cancer]. | Tumori 20010101 |
| Adjuvant therapy for colon cancer: the European experience. | Tumori 20010101 |
| A dose-finding study of irinotecan (CPT-11) plus a four-day continuous 5-fluorouracil infusion in advanced colorectal cancer. | Oncology 20010101 |
| Advances in chemotherapy for small cell lung cancer: single-agent activity of newer agents. | Cancer journal (Sudbury, Mass.) 20010101 |
| Management of chemotherapy-induced adverse effects in the treatment of colorectal cancer. | Drug safety 20010101 |
| Thalidomide in cancer: potential uses and limitations. | BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20010101 |
| A systematic overview of chemotherapy effects in colorectal cancer. | Acta oncologica (Stockholm, Sweden) 20010101 |
| A systematic overview of chemotherapy effects in non-small cell lung cancer. | Acta oncologica (Stockholm, Sweden) 20010101 |
| Morphological classification of dental lesions induced by various antitumor drugs in mice. | Toxicologic pathology 20010101 |
| Treatment of liver metastases from colorectal cancer: what is the best approach today? | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20010101 |
| The inhibitory effects of camptothecin, a topoisomerase I inhibitor, on collagen synthesis in fibroblasts from patients with systemic sclerosis. | Arthritis research 20010101 |
| Therapeutic response to octreotide in patients with refractory CPT-11 induced diarrhea. | Investigational new drugs 20010101 |
| New adjuvant therapies for esophageal cancer. | Advances in surgery 20010101 |
| Optimizing the use of irinotecan in colorectal cancer. | The oncologist 20010101 |
| New advances in lung cancer chemotherapy: topotecan and the role of topoisomerase I inhibitors. | Oncology 20010101 |
| Is cisplatin required for the treatment of non-small-cell lung cancer? Experience and preliminary results of a phase I/II trial with topotecan and vinorelbine. | Oncology 20010101 |
| Response of metastatic epidermoid anal cancer to single agent irinotecan: a case report. | Tumori 20010101 |
| Topoisomerase I interactive agents. | Cancer chemotherapy and biological response modifiers 20010101 |
| Disease management considerations: disease management considerations. | Drugs 20010101 |
| A polymorphism of the XRCC1 gene predicts for response to platinum based treatment in advanced colorectal cancer. | Anticancer research 20010101 |
| Identification and activities of human carboxylesterases for the activation of CPT-11, a clinically approved anticancer drug. | Bioconjugate chemistry 20010101 |
| Streptococcal preparation OK-432 enhances the antitumor activity of CPT-11 by increasing Th1-cytokine production in mice. | Anticancer research 20010101 |
| Controversies in the management of brain metastases: the role of chemotherapy. | Forum (Genoa, Italy) 20010101 |
| Paclitaxel: a pharmacoeconomic review of its use in non-small cell lung cancer. | PharmacoEconomics 20010101 |
| Irinotecan combined with gemcitabine, 5-fluorouracil, leucovorin, and cisplatin (G-FLIP) is an effective and noncrossresistant treatment for chemotherapy refractory metastatic pancreatic cancer. | The oncologist 20010101 |
| The development of camptothecin analogs in childhood cancers. | The oncologist 20010101 |
| Combination chemotherapy of irinotecan plus cisplatin for advanced gastric cancer: efficacy and feasibility in clinical practice. | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20010101 |
| [Irinotecan and fluorouracil in combination in colorectal carcinoma: a little clarity]. | Tumori 20010101 |
| Malignant mixed mesodermal tumor of the ovary treated with a cisplatin-irinotecan combination: case report. | European journal of gynaecological oncology 20010101 |
| Capecitabine: a review of its use in the treatment of advanced or metastatic colorectal cancer. | Drugs 20010101 |
| UGT1A1 polymorphism predicts irinotecan toxicity: evolving proof. | AAPS pharmSci 20010101 |
| Regional administration of irinotecan in combination with 5-fluorouracil and leucovorin in patients with colorectal cancer liver metastases--a pilot experience. | Hepato-gastroenterology 20010101 |
| [Irinotecan and tomudex in the treatment of patients with advanced cancer of the large intestine]. | Voprosy onkologii 20010101 |
| Severe CPT-11-induced diarrhea in presence of FK-506 following liver transplantation for hepatocellular carcinoma. | Anticancer research 20010101 |
| Irinotecan hepatic arterial infusion chemotherapy for hepatic metastases from colorectal cancer: results of a phase I clinical study. | Tumori 20010101 |
| A rapid and systematic review of the evidence for the clinical effectiveness and cost-effectiveness of irinotecan, oxaliplatin and raltitrexed for the treatment of advanced colorectal cancer. | Health technology assessment (Winchester, England) 20010101 |
| [Proceedings of the 3rd National Conference of Medical Oncology. Irinotecan: present and future. Napoli, Italy, 5 November 2001]. | Tumori 20010101 |
| [Colorectal cancer: irinotecan in combination with newer drugs]. | Tumori 20010101 |
| [Irinotecan in the treatment of stomach cancer]. | Tumori 20010101 |
| [Role of irinotecan in the treatment of small cell carcinoma]. | Tumori 20010101 |
| The inhibition of acetylcholinesterase by irinotecan and related camptothecins: key structural properties and experimental variables. | Anti-cancer drug design 20010101 |
| Irinotecan hydrochloride. | Clinical journal of oncology nursing 20010101 |
| New highly lipophilic camptothecin BNP1350 is an effective drug in experimental human cancer. | International journal of cancer 20001015 |
| Characterization of CPT-11 hydrolysis by human liver carboxylesterase isoforms hCE-1 and hCE-2. | Cancer research 20000301 |
| Comparison of in vitro activities of camptothecin and nitidine derivatives against fungal and cancer cells. | Antimicrobial agents and chemotherapy 19991201 |
| Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells. | Cancer research 19991201 |
| Bradycardia induced by irinotecan: a case report. | Japanese journal of clinical oncology 19981101 |
| Reversal of CPT-11 resistance of lung cancer cells by adenovirus-mediated gene transfer of the human carboxylesterase cDNA. | Cancer research 19981001 |
| 4-[3,5-Bis(trimethylsilyl)benzamido] benzoic acid (TAC-101) inhibits the intrahepatic spread of hepatocellular carcinoma and prolongs the life-span of tumor-bearing animals. | Clinical & experimental metastasis 19981001 |
| Identification of a new metabolite of CPT-11 (irinotecan): pharmacological properties and activation to SN-38. | The Journal of pharmacology and experimental therapeutics 19980701 |
| Clinical pharmacokinetics of irinotecan. | Clinical pharmacokinetics 19971001 |
| Therapeutic activity of CPT-11, a DNA-topoisomerase I inhibitor, against peripheral primitive neuroectodermal tumour and neuroblastoma xenografts. | British journal of cancer 19960801 |
| Comparison of topoisomerase I inhibition, DNA damage, and cytotoxicity of camptothecin derivatives presently in clinical trials. | Journal of the National Cancer Institute 19940601 |
| Therapeutic efficacy of the topoisomerase I inhibitor 7-ethyl-10-(4-[1-piperidino]-1-piperidino)-carbonyloxy-camptothecin against human tumor xenografts: lack of cross-resistance in vivo in tumors with acquired resistance to the topoisomerase I inhibitor 9-dimethylaminomethyl-10-hydroxycamptothecin. | Cancer research 19930615 |
| Antitumor effect of CPT-11, a new derivative of camptothecin, against pleiotropic drug-resistant tumors in vitro and in vivo. | Cancer chemotherapy and pharmacology 19880101 |
| Inhibition of spontaneous and experimental metastasis by a new derivative of camptothecin, CPT-11, in mice. | Cancer chemotherapy and pharmacology 19880101 |
| Antitumor activity of 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothec in, a novel water-soluble derivative of camptothecin, against murine tumors. | Cancer research 19871115 |