Home Other Building Blocks (-)-Epicatechin Gallate

(-)-Epicatechin Gallate

CAS No.:
1257-08-5
Catalog Number:
AG0035XB
Molecular Formula:
C22H18O10
Molecular Weight:
442.3723
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
95%
In Stock USA
United States
$60
- +
5mg
95%
In Stock USA
United States
$87
- +
10mg
95%
In Stock USA
United States
$101
- +
25mg
95%
In Stock USA
United States
$157
- +
50mg
95%
In Stock USA
United States
$225
- +
Product Description
Catalog Number:
AG0035XB
Chemical Name:
(-)-Epicatechin Gallate
CAS Number:
1257-08-5
Molecular Formula:
C22H18O10
Molecular Weight:
442.3723
MDL Number:
MFCD00075936
IUPAC Name:
[(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
InChI:
InChI=1S/C22H18O10/c23-11-6-14(25)12-8-19(32-22(30)10-4-16(27)20(29)17(28)5-10)21(31-18(12)7-11)9-1-2-13(24)15(26)3-9/h1-7,19,21,23-29H,8H2/t19-,21-/m1/s1
InChI Key:
LSHVYAFMTMFKBA-TZIWHRDSSA-N
SMILES:
Oc1cc(O)c2c(c1)O[C@@H]([C@@H](C2)OC(=O)c1cc(O)c(c(c1)O)O)c1ccc(c(c1)O)O
EC Number:
603-088-4
UNII:
92587OVD8Z
Properties
Complexity:
649  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
0
Exact Mass:
442.09g/mol
Formal Charge:
0
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
7  
Isotope Atom Count:
0
Molecular Weight:
442.376g/mol
Monoisotopic Mass:
442.09g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
177A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.5  
Literature
Title Journal
Tea polyphenols ameliorates neural redox imbalance and mitochondrial dysfunction via mechanisms linking the key circadian regular Bmal1. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20171201
Green tea catechins alone or in combination alter functional parameters of human neutrophils via suppressing the activation of TLR-4/NFκB p65 signal pathway. Toxicology in vitro : an international journal published in association with BIBRA 20151001
A strategy for designing a concave Pt-Ni alloy through controllable chemical etching. Angewandte Chemie (International ed. in English) 20121207
Bioactivity-guided fractionation of Phyllanthus orbicularis and identification of the principal anti HSV-2 compounds. Phytotherapy research : PTR 20121001
Influence of gallate and pyrogallol moieties on the intestinal absorption of (-)-epicatechin and (-)-epicatechin gallate. Journal of food science 20121001
Benzophenone glycosides and epicatechin derivatives from Malania oleifera. Fitoterapia 20120901
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Catechins containing a galloyl moiety as potential anti-HIV-1 compounds. Drug discovery today 20120601
Chitosan-based luminescent/magnetic hybrid nanogels for insulin delivery, cell imaging, and antidiabetic research of dietary supplements. International journal of pharmaceutics 20120510
Intervention of human breast cell carcinogenesis chronically induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. Carcinogenesis 20120401
Tea catechins and flavonoids from the leaves of Camellia sinensis inhibit yeast alcohol dehydrogenase. Bioorganic & medicinal chemistry 20120401
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Glucuronidation and methylation of procyanidin dimers b2 and 3,3″-di-o-galloyl-b2 and corresponding monomers epicatechin and 3-o-galloyl-epicatechin in mouse liver. Pharmaceutical research 20120301
(-)-Epigallocatechin-3-gallate is a new inhibitor of hepatitis C virus entry. Hepatology (Baltimore, Md.) 20120301
A tea catechin, epigallocatechin-3-gallate, is a unique modulator of the farnesoid X receptor. Toxicology and applied pharmacology 20120115
Green tea catechin intervention of reactive oxygen species-mediated ERK pathway activation and chronically induced breast cell carcinogenesis. Carcinogenesis 20120101
Simultaneous determination of catechin, epicatechin and epicatechin gallate in rat plasma by LC-ESI-MS/MS for pharmacokinetic studies after oral administration of Cynomorium songaricum extract. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120101
Characterization of creaming precipitate of tea catechins and caffeine in aqueous solution. Chemical & pharmaceutical bulletin 20120101
Dietary flavanols exert different effects on antioxidant defenses and apoptosis/proliferation in Caco-2 and SW480 colon cancer cells. Toxicology in vitro : an international journal published in association with BIBRA 20111201
Anti-staphylococcal activity and β-lactam resistance attenuating capacity of structural analogues of (-)-epicatechin gallate. Bioorganic & medicinal chemistry letters 20111201
Analysis of binding interaction between (-)-epigallocatechin (EGC) and β-lactoglobulin by multi-spectroscopic method. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111101
Effects of green tea catechins on gramicidin channel function and inferred changes in bilayer properties. FEBS letters 20111003
A profile of bioactive compounds of Rumex vesicarius L. Journal of food science 20111001
Green tea polyphenols control dysregulated glutamate dehydrogenase in transgenic mice by hijacking the ADP activation site. The Journal of biological chemistry 20110930
The lipogenesis pathway as a cancer target. Journal of medicinal chemistry 20110825
Bioactive components from the tea polyphenols influence on endogenous antioxidant defense system and modulate inflammatory cytokines after total-body irradiation in mice. Phytomedicine : international journal of phytotherapy and phytopharmacology 20110815
Comparative effects of dietary flavanols on antioxidant defences and their response to oxidant-induced stress on Caco2 cells. European journal of nutrition 20110801
Recent advances in understanding the antibacterial properties of flavonoids. International journal of antimicrobial agents 20110801
Pressurized liquid extraction of phenolic compounds from Anatolia propolis and their radical scavenging capacities. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110701
Interaction of epicatechin gallate with phospholipid membranes as revealed by solid-state NMR spectroscopy. Biochimica et biophysica acta 20110601
Effect of girdling at various positions of 'Huang Zhi Xiang' tea tree (Camellia sinensis) on the contents of catechins and starch in fresh leaf. Plant foods for human nutrition (Dordrecht, Netherlands) 20110601
Genotoxic effects of green tea extract on human laryngeal carcinoma cells in vitro. Arhiv za higijenu rada i toksikologiju 20110601
Stimulation of acidic reduction of nitrite to nitric oxide by soybean phenolics: possible relevance to gastrointestinal host defense. Journal of agricultural and food chemistry 20110525
Interactions of green tea catechins with organic anion-transporting polypeptides. Drug metabolism and disposition: the biological fate of chemicals 20110501
Epicatechin gallate and catechin gallate are superior to epigallocatechin gallate in growth suppression and anti-inflammatory activities in pancreatic tumor cells. Cancer science 20110401
Potential O-acyl-substituted (-)-Epicatechin gallate prodrugs as inhibitors of DMBA/TPA-induced squamous cell carcinoma of skin in Swiss albino mice. Chemistry & biodiversity 20110401
Evaluation of the bitterness of green tea catechins by a cell-based assay with the human bitter taste receptor hTAS2R39. Biochemical and biophysical research communications 20110225
Multistage carcinogenesis process as molecular targets in cancer chemoprevention by epicatechin-3-gallate. Food & function 20110201
Supplementation of green tea catechins in dentifrices suppresses gingival oxidative stress and periodontal inflammation. Archives of oral biology 20110101
Oligomeric proanthocyanidins from Rumex acetosa L. inhibit the attachment of herpes simplex virus type-1. Antiviral research 20110101
Effect of tea beverages on aldehyde oxidase activity. Drug metabolism and pharmacokinetics 20110101
Red wine: a source of potent ligands for peroxisome proliferator-activated receptor γ. Food & function 20110101
Analysis of the mechanism of inhibition of human matrix metalloproteinase 7 (MMP-7) activity by green tea catechins. Bioscience, biotechnology, and biochemistry 20110101
A comparative reverse docking strategy to identify potential antineoplastic targets of tea functional components and binding mode. International journal of molecular sciences 20110101
Catechin derivatives from Parapiptadenia rigida with in vitro wound-healing properties. Journal of natural products 20101227
Plasma tea polyphenol levels and subsequent risk of breast cancer among Japanese women: a nested case-control study. Breast cancer research and treatment 20101201
The evaluation of catechins that contain a galloyl moiety as potential HIV-1 integrase inhibitors. Clinical immunology (Orlando, Fla.) 20101201
Extraction of antioxidants and caffeine from green tea (Camelia sinensis) leaves: kinetics and modeling. Food science and technology international = Ciencia y tecnologia de los alimentos internacional 20101201
Genoprotective effects of the green tea-derived polyphenol/epicatechin gallate in C6 astroglial cells. Journal of medicinal food 20101001
Metabolism of green tea catechins by the human small intestine. Biotechnology journal 20101001
Epicatechin gallate suppresses oxidative stress-induced MUC5AC overexpression by interaction with epidermal growth factor receptor. American journal of respiratory cell and molecular biology 20100901
Green tea catechins are potent sensitizers of ryanodine receptor type 1 (RyR1). Biochemical pharmacology 20100815
The polyphenol epigallocatechin-3-gallate affects lipid rafts to block activation of the c-Met receptor in prostate cancer cells. Molecular carcinogenesis 20100801
Insertion of epicatechin gallate into the cytoplasmic membrane of methicillin-resistant Staphylococcus aureus disrupts penicillin-binding protein (PBP) 2a-mediated beta-lactam resistance by delocalizing PBP2. The Journal of biological chemistry 20100730
An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds. Journal of natural products 20100723
Structural characteristics of green tea catechins for formation of protein carbonyl in human serum albumin. Bioorganic & medicinal chemistry 20100715
Catechins inhibit CXCL10 production from oncostatin M-stimulated human gingival fibroblasts. The Journal of nutritional biochemistry 20100701
Tea polyphenols inhibit IL-6 production in tumor necrosis factor superfamily 14-stimulated human gingival fibroblasts. Molecular nutrition & food research 20100701
Binding affinity of tea catechins for HSA: characterization by high-performance affinity chromatography with immobilized albumin column. Molecular nutrition & food research 20100601
Epicatechin gallate decreases the viability and subsequent embryonic development of mouse blastocysts. Taiwanese journal of obstetrics & gynecology 20100601
The inhibition of collagenase induced degradation of collagen by the galloyl-containing polyphenols tannic acid, epigallocatechin gallate and epicatechin gallate. Journal of materials science. Materials in medicine 20100501
Tea catechins reduce inflammatory reactions via mitogen-activated protein kinase pathways in toll-like receptor 2 ligand-stimulated dental pulp cells. Life sciences 20100424
Effect of green tea catechins and hydrolyzable tannins on benzo[a]pyrene-induced DNA adducts and structure-activity relationship. Chemical research in toxicology 20100419
New inhibitors for expression of IgE receptor on human mast cell. Bioorganic & medicinal chemistry letters 20100401
Anti-inflammatory effect of catechin on cultured human dental pulp cells affected by bacteria-derived factors. European journal of oral sciences 20100401
Synthesis and antimicrobial activities of 3-O-alkyl analogues of (+)-catechin: improvement of stability and proposed action mechanism. European journal of medicinal chemistry 20100301
Separation of major catechins from green tea by ultrahigh pressure extraction. International journal of pharmaceutics 20100215
Statistical correlation between flavanolic composition, colour and sensorial parameters in grape seed during ripening. Analytica chimica acta 20100215
A potential proliferative gene, NUDT6, is down-regulated by green tea catechins at the posttranscriptional level. The Journal of nutritional biochemistry 20100201
Green tea catechin inhibits lipopolysaccharide-induced bone resorption in vivo. Journal of periodontal research 20100201
Tea catechins' affinity for human cannabinoid receptors. Phytomedicine : international journal of phytotherapy and phytopharmacology 20100101
Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids. Bioorganic & medicinal chemistry 20100101
In vitro drug interactions of gallates with antibiotics in Staphylococcus Aureus. Frontiers in bioscience (Elite edition) 20100101
Influence of the galloyl moiety in tea catechins on binding affinity for human serum albumin. Journal of nutritional science and vitaminology 20100101
Borate complexation-assisted field-enhanced sample injection for on-line preconcentration of cis-diol-containing compounds in capillary electrophoresis. Talanta 20091215
Binding of natural and synthetic polyphenols to human dihydrofolate reductase. International journal of molecular sciences 20091201
Ambivalent role of gallated catechins in glucose tolerance in humans: a novel insight into non-absorbable gallated catechin-derived inhibitors of glucose absorption. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20091201
Tea catechins inhibit hepatocyte growth factor receptor (MET kinase) activity in human colon cancer cells: kinetic and molecular docking studies. Journal of medicinal chemistry 20091112
Epigallocatechin-3-gallate is an inhibitor of Na+, K(+)-ATPase by favoring the E1 conformation. Biochemical pharmacology 20091015
Catechol type polyphenol is a potential modifier of protein sulfhydryls: development and application of a new probe for understanding the dietary polyphenol actions. Chemical research in toxicology 20091001
Some phenolic compounds increase the nitric oxide level in endothelial cells in vitro. Journal of agricultural and food chemistry 20090909
Green tea (-)-epigallocatechin gallate inhibits insulin stimulation of 3T3-L1 preadipocyte mitogenesis via the 67-kDa laminin receptor pathway. American journal of physiology. Cell physiology 20090701
Fast GC-FID based metabolic fingerprinting of Japanese green tea leaf for its quality ranking prediction. Journal of separation science 20090701
Disruption of D-alanyl esterification of Staphylococcus aureus cell wall teichoic acid by the {beta}-lactam resistance modifier (-)-epicatechin gallate. The Journal of antimicrobial chemotherapy 20090601
Tea polyphenols can restrict benzo[a]pyrene-induced lung carcinogenesis by altered expression of p53-associated genes and H-ras, c-myc and cyclin D1. The Journal of nutritional biochemistry 20090501
Absorption, metabolism and excretion of Choladi green tea flavan-3-ols by humans. Molecular nutrition & food research 20090501
Free radicals generated during oxidation of green tea polyphenols: electron paramagnetic resonance spectroscopy combined with density functional theory calculations. Free radical biology & medicine 20090415
Measurement of xanthine oxidase inhibition activity of phenolics and flavonoids with a modified cupric reducing antioxidant capacity (CUPRAC) method. Analytica chimica acta 20090316
Polyphenols prevent clinorotation-induced expression of atrogenes in mouse C2C12 skeletal myotubes. The journal of medical investigation : JMI 20090201
Flavonoids inhibit the AU-rich element binding of HuC. BMB reports 20090131
Protective role of tea catechins on erythrocytes subjected to oxidative stress during human aging. Natural product research 20090101
Catechins inhibit CCL20 production in IL-17A-stimulated human gingival fibroblasts. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20090101
Simultaneous determination of the major active components of tea polyphenols in rat plasma by a simple and specific HPLC assay. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081115
Antioxidant synergism of green tea polyphenols with alpha-tocopherol and L-ascorbic acid in SDS micelles. Biochimie 20081001
(-)-Epicatechin gallate accumulates in foamy macrophages in human atherosclerotic aorta: implication in the anti-atherosclerotic actions of tea catechins. Biochemical and biophysical research communications 20080926
Absorption and pharmacokinetics of green tea catechins in beagles. The British journal of nutrition 20080901
Studies on the interaction of copper complexes of (-)-epicatechin gallate and (-)-epigallocatechin gallate with calf thymus DNA. Journal of inorganic biochemistry 20080901
Presence or absence of a gallate moiety on catechins affects their cellular transport. The Journal of pharmacy and pharmacology 20080901
The impact of the 67kDa laminin receptor on both cell-surface binding and anti-allergic action of tea catechins. Archives of biochemistry and biophysics 20080815
Antioxidant effects of green tea and its polyphenols on bladder cells. Life sciences 20080704
Galloylated catechins as potent inhibitors of hypochlorous acid-induced DNA damage. Chemical research in toxicology 20080701
Stopped-flow kinetic study of the aroxyl radical-scavenging action of catechins and vitamin C in ethanol and micellar solutions. Journal of agricultural and food chemistry 20080625
Green tea catechin enhances cholesterol 7alpha-hydroxylase gene expression in HepG2 cells. The British journal of nutrition 20080601
Diastereomeric difference of inclusion modes between (-)-epicatechin gallate, (-)-epigallocatechin gallate and (+)-gallocatechin gallate, with beta-cyclodextrin in aqueous solvent. Magnetic resonance in chemistry : MRC 20080501
Effects of water-soluble natural antioxidants on photosensitized oxidation of conjugated linoleic acid in an oil-in-water emulsion system. Journal of food science 20080501
Synthesis and biological activity of a 3,4,5-trimethoxybenzoyl ester analogue of epicatechin-3-gallate. Journal of medicinal chemistry 20080410
Catechin gallates are NADP+-competitive inhibitors of glucose-6-phosphate dehydrogenase and other enzymes that employ NADP+ as a coenzyme. Bioorganic & medicinal chemistry 20080401
Potential anthelmintics: polyphenols from the tea plant Camellia sinensis L. are lethally toxic to Caenorhabditis elegans. Journal of natural medicines 20080401
Epicatechin gallate increases glutamate uptake and S100B secretion in C6 cell lineage. Molecular and cellular biochemistry 20080301
The polyphenol (-)-epicatechin gallate disrupts the secretion of virulence-related proteins by Staphylococcus aureus. Letters in applied microbiology 20080201
New polyphenols active on beta-amyloid aggregation. Bioorganic & medicinal chemistry letters 20080115
Validation of green tea polyphenol biomarkers in a phase II human intervention trial. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080101
Identification of a PKCepsilon-dependent regulation of myocardial contraction by epicatechin-3-gallate. American journal of physiology. Heart and circulatory physiology 20080101
Inhibitory effects of various beverages on human recombinant sulfotransferase isoforms SULT1A1 and SULT1A3. Biopharmaceutics & drug disposition 20071201
Structures of epicatechin gallate trimer and tetramer produced by enzymatic oxidation. Chemical & pharmaceutical bulletin 20071201
Dynamic behavior of tea catechins interacting with lipid membranes as determined by NMR spectroscopy. Journal of agricultural and food chemistry 20071128
Characterization of the constituents and antioxidant activity of Brazilian green tea (Camellia sinensis var. assamica IAC-259 cultivar) extracts. Journal of agricultural and food chemistry 20071114
Theaflavins attenuate hepatic lipid accumulation through activating AMPK in human HepG2 cells. Journal of lipid research 20071101
Green tea catechin (-)-epicatechin gallate induces tumour suppressor protein ATF3 via EGR-1 activation. European journal of cancer (Oxford, England : 1990) 20071101
A new LC/MS/MS rapid and sensitive method for the determination of green tea catechins and their metabolites in biological samples. Journal of agricultural and food chemistry 20071031
Catechin degradation with concurrent formation of homo- and heterocatechin dimers during in vitro digestion. Journal of agricultural and food chemistry 20071031
Methylation suppresses the proteasome-inhibitory function of green tea polyphenols. Journal of cellular physiology 20071001
Inhibition of HuR and MMP-9 expression in macrophage-differentiated HL-60 myeloid leukemia cells by green tea polyphenol EGCg. Leukemia research 20070901
Tea polyphenols inhibit rat vascular smooth muscle cell adhesion and migration on collagen and laminin via interference with cell-ECM interaction. Journal of biomedical science 20070901
Common tea formulations modulate in vitro digestive recovery of green tea catechins. Molecular nutrition & food research 20070901
(-)-Epicatechin-3-gallate, a green tea polyphenol is a potent agent against UVB-induced damage in HaCaT keratinocytes. Molecules (Basel, Switzerland) 20070814
Inhibitory activities of dietary phenolic compounds on heterocyclic amine formation in both chemical model system and beef patties. Molecular nutrition & food research 20070801
Uniformly-sized, molecularly imprinted polymers for (-)-epigallocatechin gallate, -epicatechin gallate and -gallocatechin gallate by multi-step swelling and polymerization method. Journal of chromatography. A 20070713
The beta-lactam-resistance modifier (-)-epicatechin gallate alters the architecture of the cell wall of Staphylococcus aureus. Microbiology (Reading, England) 20070701
Effects of infusion time and addition of milk on content and absorption of polyphenols from black tea. Journal of agricultural and food chemistry 20070613
Structure-reactivity relationships of flavan-3-ols on product generation in aqueous glucose/glycine model systems. Journal of agricultural and food chemistry 20070502
Green tea catechins upregulate superoxide dismutase and catalase in fruit flies. Molecular nutrition & food research 20070501
Epigallocatechin-3-gallate and epicatechin-3-gallate from green tea decrease plasma non-transferrin bound iron and erythrocyte oxidative stress. Medicinal chemistry (Shariqah (United Arab Emirates)) 20070501
[Dihydroflavonol glycosides and flavan-3-ols from Bauhinia aurea]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070501
Identification of major phenolic compounds of Chinese water chestnut and their antioxidant activity. Molecules (Basel, Switzerland) 20070425
The kinetics and mechanisms of the complex formation and antioxidant behaviour of the polyphenols EGCg and ECG with iron(III). Journal of inorganic biochemistry 20070401
Green tea as inhibitor of the intestinal absorption of lipids: potential mechanism for its lipid-lowering effect. The Journal of nutritional biochemistry 20070301
Green tea catechins potentiate triclosan binding to enoyl-ACP reductase from Plasmodium falciparum (PfENR). Journal of medicinal chemistry 20070222
Determination of rutin, catechin, epicatechin, and epicatechin gallate in buckwheat Fagopyrum esculentum Moench by micro-high-performance liquid chromatography with electrochemical detection. Journal of agricultural and food chemistry 20070221
Antimalarial properties of green tea. Biochemical and biophysical research communications 20070202
Effects of green tea compounds on irinotecan metabolism. Drug metabolism and disposition: the biological fate of chemicals 20070201
Attomole catechins determination by capillary liquid chromatography with electrochemical detection. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20070201
Green tea catechins inhibit bacterial DNA gyrase by interaction with its ATP binding site. Journal of medicinal chemistry 20070125
Food components inhibiting recombinant human histidine decarboxylase activity. Journal of agricultural and food chemistry 20070124
Synthesis and preliminary anticancer activity studies of C4 and C8-modified derivatives of catechin gallate (CG) and epicatechin gallate (ECG). The Journal of organic chemistry 20061222
Growth inhibition and apoptosis by (-)-epicatechin gallate are mediated by cyclin D1 suppression in head and neck squamous carcinoma cells. European journal of cancer (Oxford, England : 1990) 20061201
Epicatechin gallate, a component of green tea, reduces halotolerance in Staphylococcus aureus. International journal of food microbiology 20061001
Methylation of green tea polyphenols affects their binding to and inhibitory poses of the proteasome beta5 subunit. International journal of molecular medicine 20061001
Differential alterations in metabolic pattern of the spliceosomal UsnRNAs during pre-malignant lung lesions induced by benzo(a)pyrene: modulation by tea polyphenols. Molecular and cellular biochemistry 20060901
Sex- and strain-dependent effects of epigallocatechin gallate (EGCG) and epicatechin gallate (ECG) in the mouse. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060901
Bioassay-guided purification and identification of antimicrobial components in Chinese green tea extract. Journal of chromatography. A 20060901
Copper complexes of (-)-epicatechin gallate and (-)-epigallocatechin gallate act as inhibitors of Ribonuclease A. FEBS letters 20060821
Kinetic study of the thermal stability of tea catechins in aqueous systems using a microwave reactor. Journal of agricultural and food chemistry 20060809
Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids. Journal of medicinal chemistry 20060601
Determination of the predominant catechins in Acacia catechu by liquid chromatography/electrospray ionization-mass spectrometry. Journal of agricultural and food chemistry 20060503
Electrofocusing of methanolic extracts for identification of individual flavonol biomolecules in Camellia species. Journal of agricultural and food chemistry 20060419
The green tea catechins, (-)-Epigallocatechin-3-gallate (EGCG) and (-)-Epicatechin-3-gallate (ECG), inhibit HGF/Met signaling in immortalized and tumorigenic breast epithelial cells. Oncogene 20060323
Catalytic inhibition of human DNA topoisomerase II by interactions of grape cell culture polyphenols. Journal of agricultural and food chemistry 20060322
Cellular and in vivo hepatotoxicity caused by green tea phenolic acids and catechins. Free radical biology & medicine 20060215
Novel inhibitors of fatty-acid synthase from green tea (Camellia sinensis Xihu Longjing) with high activity and a new reacting site. Biotechnology and applied biochemistry 20060101
A quantitative approach to the free radical interaction between alpha-tocopherol or ascorbate and flavonoids. In vivo (Athens, Greece) 20060101
Assessment of the polyphenolic composition of the organic extracts of Mauritian black teas: a potential contributor to their antioxidant functions. BioFactors (Oxford, England) 20060101
The comparison of effect of catechins and green tea extract on oxidative modification of LDL in vitro. Advances in medical sciences 20060101
Stereoselective oxidation at C-4 of flavans by the endophytic fungus Diaporthe sp. isolated from a tea plant. Chemical & pharmaceutical bulletin 20051201
Antiviral effect of catechins in green tea on influenza virus. Antiviral research 20051101
Epigallocatechin-3-gallate, a polyphenol component of green tea, suppresses both collagen production and collagenase activity in hepatic stellate cells. International journal of molecular medicine 20051001
Kinetic study of the quenching reaction of singlet oxygen by tea catechins in ethanol solution. Free radical biology & medicine 20050915
Antimycobacterial agents from selected Mexican medicinal plants. The Journal of pharmacy and pharmacology 20050901
Efficiency of foam fractionation for the enrichment of nonpolar compounds from aqueous extracts of plant materials. Journal of natural products 20050901
Separation of catechin constituents from five tea cultivars using high-speed counter-current chromatography. Journal of chromatography. A 20050812
Seasonal variations of phenolic compounds in Australia-grown tea (Camellia sinensis). Journal of agricultural and food chemistry 20050810
Catechins prevent vascular smooth muscle cell invasion by inhibiting MT1-MMP activity and MMP-2 expression. Cardiovascular research 20050801
Heteroactivation of cytochrome P450 1A1 by teas and tea polyphenols. British journal of pharmacology 20050801
The absorption, metabolism and excretion of flavan-3-ols and procyanidins following the ingestion of a grape seed extract by rats. The British journal of nutrition 20050801
Theaflavin derivatives in black tea and catechin derivatives in green tea inhibit HIV-1 entry by targeting gp41. Biochimica et biophysica acta 20050525
Kinetics of the inhibition of bovine liver dihydrofolate reductase by tea catechins: origin of slow-binding inhibition and pH studies. Biochemistry 20050524
Synthesis and antibacterial activity of hydrolytically stable (-)-epicatechin gallate analogues for the modulation of beta-lactam resistance in Staphylococcus aureus. Bioorganic & medicinal chemistry letters 20050516
Inhibition of human liver catechol-O-methyltransferase by tea catechins and their metabolites: structure-activity relationship and molecular-modeling studies. Biochemical pharmacology 20050515
Structure-activity relationship of the tocopherol-regeneration reaction by catechins. Free radical biology & medicine 20050501
Dietary gallate esters of tea catechins reduce deposition of visceral fat, hepatic triacylglycerol, and activities of hepatic enzymes related to fatty acid synthesis in rats. Bioscience, biotechnology, and biochemistry 20050501
Protective effects of (-)-epicatechin-3-gallate on UVA-induced damage in HaCaT keratinocytes. Archives of dermatological research 20050401
Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins. The Journal of biological chemistry 20050304
Differential in vitro cytotoxicity of (-)-epicatechin gallate (ECG) to cancer and normal cells from the human oral cavity. Toxicology in vitro : an international journal published in association with BIBRA 20050301
Flavanols in somatic cell division and male meiosis of tea (Camellia sinensis) anthers. Plant biology (Stuttgart, Germany) 20050301
Pharmacokinetics of TJ-8117(Onpi-to), a drug for renal failure (II): effects of food, repeated administration and renal failure to plasma concentration of [3H]-(-)epicatechin 3-O-gallate in rats. European journal of drug metabolism and pharmacokinetics 20050101
Investigation of intestinal absorption and disposition of green tea catechins by Caco-2 monolayer model. International journal of pharmaceutics 20041209
Epicatechin gallate-induced expression of NAG-1 is associated with growth inhibition and apoptosis in colon cancer cells. Carcinogenesis 20041201
Ellipsometry analysis of the in vitro adsorption of tea polyphenols onto salivary pellicles. European journal of oral sciences 20041201
Hypoxia-inducible factor-1 activation by (-)-epicatechin gallate: potential adverse effects of cancer chemoprevention with high-dose green tea extracts. Journal of natural products 20041201
Catechin gallates inhibit multidrug resistance (MDR) in Staphylococcus aureus. Planta medica 20041201
[Preparation and component analysis of tea pigments]. Wei sheng yan jiu = Journal of hygiene research 20041101
Anticancer activity of 3-O-acyl and alkyl-(-)-epicatechin derivatives. Bioorganic & medicinal chemistry letters 20041018
Prooxidative activities of tea catechins in the presence of Cu2+. Bioscience, biotechnology, and biochemistry 20040901
Glucuronidation of the green tea catechins, (-)-epigallocatechin-3-gallate and (-)-epicatechin-3-gallate, by rat hepatic and intestinal microsomes. Free radical research 20040901
Study of the green tea polyphenols catechin-3-gallate (CG) and epicatechin-3-gallate (ECG) as proteasome inhibitors. Bioorganic & medicinal chemistry 20040701
Effects of epicatechin gallate on wound healing and scar formation in a full thickness incisional wound healing model in rats. The American journal of pathology 20040701
Effect of tea catechins on the change of glutathione levels caused by Pb(++) in PC12 cells. Chemical research in toxicology 20040701
Polyphenols from Camellia sinenesis prevent primary graft failure after transplantation of ethanol-induced fatty livers from rats. Free radical biology & medicine 20040515
Modulation of beta-lactam resistance in Staphylococcus aureus by catechins and gallates. International journal of antimicrobial agents 20040501
Inhibitory effect of green tea catechins on cysteine proteinases in Porphyromonas gingivalis. Oral microbiology and immunology 20040401
[MDR-reversing effect of two components of catechin on human hepatocellular carcinoma BEL-7404/Adr in vitro]. Ai zheng = Aizheng = Chinese journal of cancer 20040401
Role of hydrogen peroxide in bactericidal action of catechin. Biological & pharmaceutical bulletin 20040301
(-)-Epicatechin 3-O-gallate ameliorates the damages related to peroxynitrite production by mechanisms distinct from those of other free radical inhibitors. The Journal of pharmacy and pharmacology 20040201
Unravelling green tea's mechanisms of action: more than meets the eye. Molecular pharmacology 20040101
Pharmacokinetics of TJ-8117 (Onpi-to), a drug for renal failure (I): Plasma concentration, distribution and excretion of [3H]-(-)epicatechin 3-O-gallate in rats and dogs. European journal of drug metabolism and pharmacokinetics 20040101
A difference between epigallocatechin-3-gallate and epicatechin-3-gallate on anti-allergic effect is dependent on their distinct distribution to lipid rafts. BioFactors (Oxford, England) 20040101
Tea polyphenols inhibit the transport of dietary phenolic acids mediated by the monocarboxylic acid transporter (MCT) in intestinal Caco-2 cell monolayers. Journal of agricultural and food chemistry 20031203
Heat-epimerized tea catechins rich in gallocatechin gallate and catechin gallate are more effective to inhibit cholesterol absorption than tea catechins rich in epigallocatechin gallate and epicatechin gallate. Journal of agricultural and food chemistry 20031203
Epigallocatechin gallate modulates CYP450 isoforms in the female Swiss-Webster mouse. Toxicological sciences : an official journal of the Society of Toxicology 20031201
The galloyl moiety of green tea catechins is the critical structural feature to inhibit fatty-acid synthase. Biochemical pharmacology 20031115
Cellular uptake and efflux of the tea flavonoid (-)epicatechin-3-gallate in the human intestinal cell line Caco-2. The Journal of pharmacology and experimental therapeutics 20031101
Catechins and the treatment of breast cancer: possible utility and mechanistic targets. IDrugs : the investigational drugs journal 20031101
Epigallocatechin gallate, the main component of tea polyphenol, binds to CD4 and interferes with gp120 binding. The Journal of allergy and clinical immunology 20031101
Involvement of multidrug resistance-associated proteins in regulating cellular levels of (-)-epigallocatechin-3-gallate and its methyl metabolites. Biochemical and biophysical research communications 20031010
Tea catechins protect against lead-induced ROS formation, mitochondrial dysfunction, and calcium dysregulation in PC12 cells. Chemical research in toxicology 20030901
A combination effect of epigallocatechin gallate, a major compound of green tea catechins, with antibiotics on Helicobacter pylori growth in vitro. Current microbiology 20030901
Identification of metabolites of (-)-epicatechin gallate and their metabolic fate in the rat. Journal of agricultural and food chemistry 20030827
A novel convenient process to obtain a raw decaffeinated tea polyphenol fraction using a lignocellulose column. Journal of agricultural and food chemistry 20030507
Pharmacokinetics of (-)-epicatechin-3-O-gallate, an active component of Onpi-to, in rats. Biological & pharmaceutical bulletin 20030501
Tea catechin synergies in inhibition of cancer cell proliferation and of a cancer specific cell surface oxidase (ECTO-NOX). Pharmacology & toxicology 20030501
Protective activity of (-)-epicatechin 3-O-gallate against peroxynitrite-mediated renal damage. Free radical research 20030501
Inhibition of adenovirus infection and adenain by green tea catechins. Antiviral research 20030401
The relationship between the antioxidant and the antibacterial properties of galloylated catechins and the structure of phospholipid model membranes. Free radical biology & medicine 20030315
Green tea polyphenol targets the mitochondria in tumor cells inducing caspase 3-dependent apoptosis. Anticancer research 20030101
Direct scavenging of nitric oxide and superoxide by green tea. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021201
Green tea polyphenols inhibit metalloproteinase activities in the skin, muscle, and blood of rainbow trout. Journal of agricultural and food chemistry 20021120
Tea enhances insulin activity. Journal of agricultural and food chemistry 20021120
Polyphenol-induced inhibition of the response of na(+)/glucose cotransporter expressed in Xenopus oocytes. Journal of agricultural and food chemistry 20020828
Spectrofluorometric determination of catechins with 1,2-diphenylethylenediamine. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20020801
Effects of tea components on the response of GABA(A) receptors expressed in Xenopus Oocytes. Journal of agricultural and food chemistry 20020703
Effect of tea catechins on cellular lipid peroxidation and cytotoxicity in HepG2 cells. Bioscience, biotechnology, and biochemistry 20020701
Inhibition of the PDGF beta-receptor tyrosine phosphorylation and its downstream intracellular signal transduction pathway in rat and human vascular smooth muscle cells by different catechins. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020601
Study of non-covalent complexation between catechin derivatives and peptides by electrospray ionization mass spectrometry. Journal of mass spectrometry : JMS 20020601
Antimutagenic activity of selenium-enriched green tea toward the heterocyclic amine 2-amino-3-methylimidazo[4,5-f]quinoline. Biological trace element research 20020501
Protective activity of green tea against free radical- and glucose-mediated protein damage. Journal of agricultural and food chemistry 20020410
Enhancement of inward Ca(2+) currents in bovine chromaffin cells by green tea polyphenol extracts. Neurochemistry international 20020201
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Kinetic analysis and mechanistic aspects of autoxidation of catechins. Biochimica et biophysica acta 20020115
Plasma concentrations of individual tea catechins after a single oral dose in humans. Xenobiotica; the fate of foreign compounds in biological systems 20011201
Effects of purified green and black tea polyphenols on cyclooxygenase- and lipoxygenase-dependent metabolism of arachidonic acid in human colon mucosa and colon tumor tissues. Biochemical pharmacology 20011101
Simplified catechin-gallate inhibitors of HIV-1 reverse transcriptase. Bioorganic & medicinal chemistry letters 20011022
Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450. Mutation research 20010808
Prolyl endopeptidase inhibitors from green tea. Archives of pharmacal research 20010801
Stereospecificity in membrane effects of catechins. Chemico-biological interactions 20010314
The effects of phenolic components of tea on the production of pro- and anti-inflammatory cytokines by human leukocytes in vitro. Cytokine 20010307
Structural features of procyanidin interactions with salivary proteins. Journal of agricultural and food chemistry 20010201
Degradation of green tea catechins in tea drinks. Journal of agricultural and food chemistry 20010101
Pharmacokinetics and system linearity of tea catechins in rat. Xenobiotica; the fate of foreign compounds in biological systems 20010101
Influence of metal ions on flavonoid protection against asbestos-induced cell injury. Archives of biochemistry and biophysics 20010101
Green tea and its catechins inhibit breast cancer xenografts. Nutrition and cancer 20010101
Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. Nutrition and cancer 20010101
Prolyl endopeptidase inhibitory activity of fourteen Kampo formulas and inhibitory constituents of Tokaku-joki-to. Chemical & pharmaceutical bulletin 20000701
Inhibition of 12-O-tetradecanoylphorbol-13-acetate and other skin tumor-promoter-caused induction of epidermal interleukin-1 alpha mRNA and protein expression in SENCAR mice by green tea polyphenols. The Journal of investigative dermatology 19950901
Inhibition of HIV infection by flavanoids. Antiviral research 19931001
Inhibition of human immunodeficiency viral replication by tannins and related compounds. Antiviral research 19920501
Differential inhibitory effects of some catechin derivatives on the activities of human immunodeficiency virus reverse transcriptase and cellular deoxyribonucleic and ribonucleic acid polymerases. Biochemistry 19900320
Differential inhibition of HIV-reverse transcriptase and various DNA and RNA polymerases by some catechin derivatives. Nucleic acids symposium series 19890101
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