N-[2-(diethylamino)ethyl]-5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-2,4-dimethyl-1H-pyrrole-3-carboxamide
| Title | Journal |
|---|---|
| Sunitinib induces hepatocyte mitochondrial damage and apoptosis in mice. | Toxicology 20181101 |
| Cytotoxicity of 34 FDA approved small-molecule kinase inhibitors in primary rat and human hepatocytes. | Toxicology letters 20180701 |
| Human precision-cut liver slices as a model to test antifibrotic drugs in the early onset of liver fibrosis. | Toxicology in vitro : an international journal published in association with BIBRA 20160901 |
| Differential Effects of Sunitinib on the Expression Profiles of Xenobiotic-Metabolizing Enzymes and Transporters in Rat Liver and Kidneys. | Basic & clinical pharmacology & toxicology 20160801 |
| Inflammatory and fibrotic processes are involved in the cardiotoxic effect of sunitinib: Protective role of L-carnitine. | Toxicology letters 20160122 |
| Identification of a Mitochondrial DNA Polymerase Affecting Cardiotoxicity of Sunitinib Using a Genome-Wide Screening on S. pombe Deletion Library. | Toxicological sciences : an official journal of the Society of Toxicology 20160101 |
| Bridging Functional and Structural Cardiotoxicity Assays Using Human Embryonic Stem Cell-Derived Cardiomyocytes for a More Comprehensive Risk Assessment. | Toxicological sciences : an official journal of the Society of Toxicology 20151101 |
| Utilization of human nuclear receptors as an early counter screen for off-target activity: a case study with a compendium of 615 known drugs. | Toxicological sciences : an official journal of the Society of Toxicology 20150601 |
| Suppression of cancer relapse and metastasis by inhibiting cancer stemness. | Proceedings of the National Academy of Sciences of the United States of America 20150210 |
| Association of single nucleotide polymorphisms in IL8 and IL13 with sunitinib-induced toxicity in patients with metastatic renal cell carcinoma. | European journal of clinical pharmacology 20150101 |
| Structure-activity relationship of 3,5-diaryl-2-aminopyridine ALK2 inhibitors reveals unaltered binding affinity for fibrodysplasia ossificans progressiva causing mutants. | Journal of medicinal chemistry 20141009 |
| Chloroquine synergizes sunitinib cytotoxicity via modulating autophagic, apoptotic and angiogenic machineries. | Chemico-biological interactions 20140625 |
| Development of cardiac hypertrophy by sunitinib in vivo and in vitro rat cardiomyocytes is influenced by the aryl hydrocarbon receptor signaling pathway. | Archives of toxicology 20140301 |
| Precision-cut liver slices as a model for the early onset of liver fibrosis to test antifibrotic drugs. | Toxicology and applied pharmacology 20140115 |
| A high-throughput screen for teratogens using human pluripotent stem cells. | Toxicological sciences : an official journal of the Society of Toxicology 20140101 |
| Flumatinib, a selective inhibitor of BCR-ABL/PDGFR/KIT, effectively overcomes drug resistance of certain KIT mutants. | Cancer science 20140101 |
| Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model. | Toxicological sciences : an official journal of the Society of Toxicology 20131201 |
| Multi-parameter in vitro toxicity testing of crizotinib, sunitinib, erlotinib, and nilotinib in human cardiomyocytes. | Toxicology and applied pharmacology 20131001 |
| Identification of potent Yes1 kinase inhibitors using a library screening approach. | Bioorganic & medicinal chemistry letters 20130801 |
| The development of CNS-active LRRK2 inhibitors using property-directed optimisation. | Bioorganic & medicinal chemistry letters 20130701 |
| Sunitinib, a tyrosine kinase inhibitor, induces cytochrome P450 1A1 gene in human breast cancer MCF7 cells through ligand-independent aryl hydrocarbon receptor activation. | Archives of toxicology 20130501 |
| Simultaneous analysis of anticancer agents bortezomib, imatinib, nilotinib, dasatinib, erlotinib, lapatinib, sorafenib, sunitinib and vandetanib in human plasma using LC/MS/MS. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20130501 |
| A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery. | The Biochemical journal 20130415 |
| Activity-based kinase profiling of approved tyrosine kinase inhibitors. | Genes to cells : devoted to molecular & cellular mechanisms 20130201 |
| A novel chordoma xenograft allows in vivo drug testing and reveals the importance of NF-κB signaling in chordoma biology. | PloS one 20130101 |
| A combination of liposomal sunitinib plus liposomal irinotecan and liposome co-loaded with two drugs enhanced antitumor activity in PC12-bearing mouse. | Journal of drug targeting 20121201 |
| Identification of novel scaffold of benzothiazepinones as non-ATP competitive glycogen synthase kinase-3β inhibitors through virtual screening. | Bioorganic & medicinal chemistry letters 20121201 |
| A pilot study of sunitinib malate in patients with metastatic uveal melanoma. | Melanoma research 20121201 |
| Quantitation of unbound sunitinib and its metabolite N-desethyl sunitinib (SU12662) in human plasma by equilibrium dialysis and liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study. | Biomedical chromatography : BMC 20121101 |
| Sunitinib causes dose-dependent negative functional effects on myocardium and cardiomyocytes. | BJU international 20121101 |
| Systematic classification and prediction of complications after nephrectomy in patients with metastatic renal cell carcinoma (RCC). | BJU international 20121101 |
| An indirect comparison of the toxicity of sunitinib and pazopanib in metastatic clear cell renal cancer. | European journal of cancer (Oxford, England : 1990) 20121101 |
| Determination of soluble vascular endothelial growth factor receptor 3 (sVEGFR-3) in plasma as pharmacodynamic biomarker. | Journal of pharmaceutical and biomedical analysis 20121101 |
| Activation of alternate prosurvival pathways accounts for acquired sunitinib resistance in U87MG glioma xenografts. | The Journal of pharmacology and experimental therapeutics 20121101 |
| Glioblastoma resistance to anti-VEGF therapy is associated with myeloid cell infiltration, stem cell accumulation, and a mesenchymal phenotype. | Neuro-oncology 20121101 |
| Multitargeted tyrosine kinase inhibition produces discordant changes between 99mTc-MDP bone scans and other disease biomarkers: analysis of a phase II study of sunitinib for metastatic castration-resistant prostate cancer. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20121101 |
| Lung toxicity in a patient treated with sunitinib. | The European respiratory journal 20121101 |
| Sunitinib inhibits catecholamine synthesis and secretion in pheochromocytoma tumor cells by blocking VEGF receptor 2 via PLC-γ-related pathways. | American journal of physiology. Endocrinology and metabolism 20121015 |
| Dynamic changes of live/apoptotic circulating tumour cells as predictive marker of response to sunitinib in metastatic renal cancer. | British journal of cancer 20121009 |
| Dose escalation and pharmacokinetics study of enzastaurin and sunitinib versus placebo and sunitinib in patients with metastatic renal cell carcinoma. | American journal of clinical oncology 20121001 |
| Sunitinib, a receptor tyrosine kinase inhibitor, increases blood pressure in rats without associated changes in cardiac structure and function. | Cardiovascular therapeutics 20121001 |
| Neoadjuvant therapy of renal cell carcinoma: a novel treatment option in the era of targeted therapy? | International journal of urology : official journal of the Japanese Urological Association 20121001 |
| C-reactive protein as a prognostic marker for advanced renal cell carcinoma treated with sunitinib. | International journal of urology : official journal of the Japanese Urological Association 20121001 |
| Platelet-derived growth factor may be a potential diagnostic and prognostic marker for cholangiocarcinoma. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20121001 |
| Immunotherapy and targeted therapies in metastatic renal cell carcinoma: is there a preferred sequence? | Cancer biotherapy & radiopharmaceuticals 20121001 |
| Blockade of NFκB activity by Sunitinib increases cell death in Bortezomib-treated endometrial carcinoma cells. | Molecular oncology 20121001 |
| Role of operative therapy in treatment of metastatic gastrointestinal stromal tumors. | The Journal of surgical research 20121001 |
| A prospective phase II single-institution trial of sunitinib for recurrent malignant glioma. | Journal of neuro-oncology 20121001 |
| Sunitinib in refractory adrenocortical carcinoma: a phase II, single-arm, open-label trial. | The Journal of clinical endocrinology and metabolism 20121001 |
| Phase I trial of sunitinib and gemcitabine in patients with advanced solid tumors. | Cancer chemotherapy and pharmacology 20121001 |
| Polymorphisms in endothelial nitric oxide synthase (eNOS) and vascular endothelial growth factor (VEGF) predict sunitinib-induced hypertension. | Clinical pharmacology and therapeutics 20121001 |
| Sunitinib- and sorafenib-induced nephrotic syndrome in a patient with gastrointestinal stromal tumor. | The Annals of pharmacotherapy 20121001 |
| Sunitinib can enhance BCG mediated cytotoxicity to transitional cell carcinoma through apoptosis pathway. | Urologic oncology 20120901 |
| The impact of sunitinib-induced hypothyroidism on progression-free survival of metastatic renal cancer patients: a prospective single-center study. | Urologic oncology 20120901 |
| Thyroid size change by CT monitoring after sorafenib or sunitinib treatment in patients with renal cell carcinoma: comparison with thyroid function. | European journal of radiology 20120901 |
| Sequential use of sorafenib and sunitinib in advanced renal cell carcinoma: does the order of sequencing matter? | Medical oncology (Northwood, London, England) 20120901 |
| Endothelial follicle stimulating hormone receptor in primary kidney cancer correlates with subsequent response to sunitinib. | Journal of cellular and molecular medicine 20120901 |
| A phase II clinical trial of sunitinib following hepatic transarterial embolization for metastatic neuroendocrine tumors. | Annals of oncology : official journal of the European Society for Medical Oncology 20120901 |
| Use of tyrosine kinase inhibitors in patients with metastatic kidney cancer receiving haemodialysis: a retrospective Italian survey. | BJU international 20120901 |
| A phase II trial (AGO 2.11) in platinum-resistant ovarian cancer: a randomized multicenter trial with sunitinib (SU11248) to evaluate dosage, schedule, tolerability, toxicity and effectiveness of a multitargeted receptor tyrosine kinase inhibitor monotherapy. | Annals of oncology : official journal of the European Society for Medical Oncology 20120901 |
| Sunitinib malate provides activity against murine bladder tumor growth and invasion in a preclinical orthotopic model. | Urology 20120901 |
| Unusual short-term complete response to two regimens of cytotoxic chemotherapy in a patient with poorly differentiated thyroid carcinoma. | The Journal of clinical endocrinology and metabolism 20120901 |
| Sunitinib plus erlotinib for the treatment of advanced/metastatic non-small-cell lung cancer: a lead-in study. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20120901 |
| A phase II study of intermittent sunitinib malate as second-line therapy in progressive malignant pleural mesothelioma. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20120901 |
| [Partial nephrectomy after neoadjuvant administration of sunitinib facilitates preservation of a solitary kidney]. | Aktuelle Urologie 20120901 |
| Resistance to targeted therapies in pancreatic neuroendocrine tumors (PNETs): molecular basis, preclinical data, and counteracting strategies. | Targeted oncology 20120901 |
| Rapid relapse after resection of a sunitinib-resistant gastrointestinal stromal tumor harboring a secondary mutation in exon 13 of the c-KIT gene. | Anticancer research 20120901 |
| [Responses to treatment and switching tyrosine kinase inhibitors in gastrointestinal stromal tumor(GIST)]. | Gan to kagaku ryoho. Cancer & chemotherapy 20120901 |
| [A case of interstitial lung disease due to sunitinib]. | Hinyokika kiyo. Acta urologica Japonica 20120901 |
| [Cardiac tamponade due to pericardial metastasis from renal cell carcinoma : a case report]. | Hinyokika kiyo. Acta urologica Japonica 20120901 |
| Sunitinib synergizes the antitumor effect of cisplatin via modulation of ERCC1 expression in models of gastric cancer. | Cancer letters 20120828 |
| Takotsubo syndrome in a patient treated with sunitinib for renal cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120820 |
| Sunitinib-induced changes in circulating endothelial cell-related proteins in patients with metastatic renal cell cancer. | International journal of cancer 20120815 |
| Sequential therapy with sunitinib and sorafenib in metastatic hepatocellular carcinoma. | Investigational new drugs 20120801 |
| Docetaxel combined with targeted therapies in metastatic breast cancer. | Cancer treatment reviews 20120801 |
| Two cases of bowel perforation associated with sunitinib treatment for renal cell carcinoma. | International journal of clinical oncology 20120801 |
| Managing progressive disease in patients with GIST: factors to consider besides acquired secondary tyrosine kinase inhibitor resistance. | Cancer treatment reviews 20120801 |
| VEGF-A/VEGFR-2 signaling plays an important role for the motility of pancreas cancer cells. | Annals of surgical oncology 20120801 |
| Multicenter phase II study of sunitinib in patients with non-clear cell renal cell carcinoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20120801 |
| Clinical and pharmacokinetic study of sunitinib and docetaxel in women with advanced breast cancer. | Breast (Edinburgh, Scotland) 20120801 |
| Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model. | The Journal of pathology 20120801 |
| Sunitinib targets PDGF-receptor and Flt3 and reduces survival and migration of human meningioma cells. | European journal of cancer (Oxford, England : 1990) 20120801 |
| Reproductive toxicity assessment of sunitinib, a multitargeted receptor tyrosine kinase inhibitor, in male and female rats. | Birth defects research. Part B, Developmental and reproductive toxicology 20120801 |
| First-line sunitinib plus FOLFIRI in Japanese patients with unresectable/metastatic colorectal cancer: a phase II study. | Cancer science 20120801 |
| Phase II study of maintenance sunitinib following irinotecan and carboplatin as first-line treatment for patients with extensive-stage small-cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20120801 |
| A case of acute adrenal insufficiency unmasked during sunitinib treatment for metastatic renal cell carcinoma. | Japanese journal of clinical oncology 20120801 |
| Differential drug class-specific metastatic effects following treatment with a panel of angiogenesis inhibitors. | The Journal of pathology 20120801 |
| Anti-VEGF antibody therapy does not promote metastasis in genetically engineered mouse tumour models. | The Journal of pathology 20120801 |
| Thyroid dysfunction in patients treated with tyrosine kinase inhibitors, sunitinib, sorafenib and axitinib, for metastatic renal cell carcinoma. | Japanese journal of clinical oncology 20120801 |
| Effect of sunitinib on functional reproductive outcome in a rabbit model. | Fertility and sterility 20120801 |
| The design, synthesis, and biological evaluation of potent receptor tyrosine kinase inhibitors. | Bioorganic & medicinal chemistry letters 20120801 |
| FDA approval summary: sunitinib for the treatment of progressive well-differentiated locally advanced or metastatic pancreatic neuroendocrine tumors. | The oncologist 20120801 |
| Targeting angiogenesis in metastatic breast cancer. | The oncologist 20120801 |
| Extreme hypothyroidism associated with sunitinib treatment for metastatic renal cancer. | Journal of chemotherapy (Florence, Italy) 20120801 |
| PRKX, TTBK2 and RSK4 expression causes Sunitinib resistance in kidney carcinoma- and melanoma-cell lines. | International journal of cancer 20120715 |
| The curative efficacy of namitecan (ST1968) in preclinical models of pediatric sarcoma is associated with antiangiogenic effects. | Biochemical pharmacology 20120715 |
| Rapid angiogenesis onset after discontinuation of sunitinib treatment of renal cell carcinoma patients. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120715 |
| Novel tricyclic indeno[2,1-d]pyrimidines with dual antiangiogenic and cytotoxic activities as potent antitumor agents. | Bioorganic & medicinal chemistry 20120715 |
| A biodegradable perivascular wrap for controlled, local and directed drug delivery. | Journal of controlled release : official journal of the Controlled Release Society 20120710 |
| Sunitinib-induced microangiopathic hemolytic anemia with fatal outcome. | American journal of therapeutics 20120701 |
| Lung Aspergillosis in renal cell carcinoma patient treated with sunitinib. | QJM : monthly journal of the Association of Physicians 20120701 |
| Angiostatic kinase inhibitors to sustain photodynamic angio-occlusion. | Journal of cellular and molecular medicine 20120701 |
| Fingolimod potentiates the effects of sunitinib malate in a rat breast cancer model. | Breast cancer research and treatment 20120701 |
| HGF/c-Met pathway is one of the mediators of sunitinib-induced tumor cell type-dependent metastasis. | Cancer letters 20120701 |
| Phase III study of nilotinib versus best supportive care with or without a TKI in patients with gastrointestinal stromal tumors resistant to or intolerant of imatinib and sunitinib. | Annals of oncology : official journal of the European Society for Medical Oncology 20120701 |
| High CXCR4 expression correlates with sunitinib poor response in metastatic renal cancer. | Current cancer drug targets 20120701 |
| Modulation of Akt/mTOR signaling overcomes sunitinib resistance in renal and prostate cancer cells. | Molecular cancer therapeutics 20120701 |
| 2-Anilino-4-(benzimidazol-2-yl)pyrimidines--a multikinase inhibitor scaffold with antiproliferative activity toward cancer cell lines. | European journal of medicinal chemistry 20120701 |
| Adjuvant therapy of gastrointestinal stromal tumors. | Current opinion in oncology 20120701 |
| In vivo, in vitro toxicity and in vitro angiogenic inhibition of sunitinib malate. | Current eye research 20120701 |
| Efficacy and safety of regorafenib in patients with metastatic and/or unresectable GI stromal tumor after failure of imatinib and sunitinib: a multicenter phase II trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120701 |
| A phase I study of sunitinib combined with modified FOLFOX6 in patients with advanced solid tumors. | Cancer chemotherapy and pharmacology 20120701 |
| Implications of the new histological classification (WHO 2010) for pancreatic neuroendocrine neoplasms. | Annals of oncology : official journal of the European Society for Medical Oncology 20120701 |
| Efficacy of sequential treatment with sunitinib-everolimus in an orthotopic mouse model of renal cell carcinoma. | Anticancer research 20120701 |
| Osteonecrosis of the jaws in patients assuming bisphosphonates and sunitinib: two case reports. | European review for medical and pharmacological sciences 20120701 |
| [A case of advanced renal cell carcinoma with inferior vena cava thrombus treated with sunitinib as neoadjuvant therapy]. | Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20120701 |
| Sunitinib-induced hyperparathyroidism: a possible mechanism to altered bone homeostasis. | Cancer 20120615 |
| Sunitinib plus erlotinib versus placebo plus erlotinib in patients with previously treated advanced non-small-cell lung cancer: a phase III trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120610 |
| Sequential treatment with sorafenib and sunitinib in metastatic renal cell carcinoma: clinical outcomes from a retrospective clinical study. | Medical oncology (Northwood, London, England) 20120601 |
| Concurrent and sequential administration of sunitinib malate and docetaxel in human non-small cell lung cancer cells and xenografts. | Medical oncology (Northwood, London, England) 20120601 |
| Safety and treatment patterns of angiogenesis inhibitors in patients with metastatic renal cell carcinoma: evidence from US community oncology clinics. | Medical oncology (Northwood, London, England) 20120601 |
| Simultaneous targeting of Src kinase and receptor tyrosine kinase results in synergistic inhibition of renal cell carcinoma proliferation and migration. | International journal of cancer 20120601 |
| Systematic review of escalated imatinib doses compared with sunitinib or best supportive care, for the treatment of people with unresectable/metastatic gastrointestinal stromal tumours whose disease has progressed on the standard imatinib dose. | Journal of gastrointestinal cancer 20120601 |
| Primary anti-vascular endothelial growth factor (VEGF)-refractory metastatic renal cell carcinoma: clinical characteristics, risk factors, and subsequent therapy. | Annals of oncology : official journal of the European Society for Medical Oncology 20120601 |
| A phase II study of sunitinib in recurrent and/or metastatic adenoid cystic carcinoma (ACC) of the salivary glands: current progress and challenges in evaluating molecularly targeted agents in ACC. | Annals of oncology : official journal of the European Society for Medical Oncology 20120601 |
| Sunitinib inhibits the phosphorylation of platelet-derived growth factor receptor β in the skin of mice with scleroderma-like features and prevents the development of the disease. | Arthritis and rheumatism 20120601 |
| Complete response after sequential sunitinib-sorafenib treatment in a patient with renal cell carcinoma: a case report. | Clinical genitourinary cancer 20120601 |
| Is there a role for targeted therapies in the collecting ducts of Bellini carcinoma? Efficacy data from a retrospective analysis of 7 cases. | Clinical and experimental nephrology 20120601 |
| Is apparent diffusion coefficient reliable and accurate for monitoring effects of antiangiogenic treatment in a longitudinal study? | Journal of magnetic resonance imaging : JMRI 20120601 |
| Combination of Temsirolimus and tyrosine kinase inhibitors in renal carcinoma and endothelial cell lines. | Journal of cancer research and clinical oncology 20120601 |
| Current treatment considerations in metastatic renal cell carcinoma. | Current treatment options in oncology 20120601 |
| Pancreatic neuroendocrine and carcinoid tumors: what's new, what's old, and what's different? | Current oncology reports 20120601 |
| Activation of the RAS/RAF/ERK signaling pathway contributes to resistance to sunitinib in thyroid carcinoma cell lines. | The Journal of clinical endocrinology and metabolism 20120601 |
| Underestimating cardiac toxicity in cancer trials: lessons learned? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120601 |
| Circulating biomarkers of response to sunitinib in gastroenteropancreatic neuroendocrine tumors: current data and clinical outlook. | Molecular diagnosis & therapy 20120601 |
| Management of sunitinib adverse events in renal cell carcinoma patients: the Asian experience. | Asia-Pacific journal of clinical oncology 20120601 |
| Imaging response in neuroendocrine tumors treated with targeted therapies: the experience of sunitinib. | Targeted oncology 20120601 |
| New targeted agents in gastroenteropancreatic neuroendocrine tumors. | Targeted oncology 20120601 |
| Sunitinib malate for the treatment of renal cell carcinoma. | Expert opinion on pharmacotherapy 20120601 |
| Sunitinib in pancreatic neuroendocrine tumors. | Targeted oncology 20120601 |
| Complete longitudinal analyses of the randomized, placebo-controlled, phase III trial of sunitinib in patients with gastrointestinal stromal tumor following imatinib failure. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120601 |
| Multi-targeted tyrosine kinase inhibitor sunitinib: a novel strategy for sporadic malignant pheochromocytoma. | Chinese medical journal 20120601 |
| [Secondary mutation of c-kit/PDGFRα genotypes after imatinib mesylate therapy and its relationship with efficacy of sunitinib]. | Zhonghua bing li xue za zhi = Chinese journal of pathology 20120601 |
| Q-TWiST analysis to estimate overall benefit for patients with metastatic renal cell carcinoma treated in a phase III trial of sunitinib vs interferon-α. | British journal of cancer 20120508 |
| Novel molecular targeted therapies for refractory thyroid cancer. | Head & neck 20120501 |
| Clinical efficacy and prognostic factors for overall survival in Japanese patients with metastatic renal cell cancer treated with sunitinib. | BJU international 20120501 |
| Patterns of care, prognosis, and survival in patients with metastatic gastrointestinal stromal tumors (GIST) refractory to first-line imatinib and second-line sunitinib. | Annals of surgical oncology 20120501 |
| Antitumor effect of vascular endothelial growth factor inhibitor sunitinib in preclinical models of hepatocellular carcinoma. | European journal of gastroenterology & hepatology 20120501 |
| Cancer therapy modulates VEGF signaling and viability in adult rat cardiac microvascular endothelial cells and cardiomyocytes. | Journal of molecular and cellular cardiology 20120501 |
| Evaluation of subchronic toxicity of SIM010603, a potent inhibitor of receptor tyrosine kinase, after 28-day repeated oral administration in SD rats and beagle dogs. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120501 |
| Sunitinib enhances antitumor effects against chemotherapy-resistant bladder cancer through suppression of ERK1/2 phosphorylation. | International journal of oncology 20120501 |
| Incidence of thyroid hormone therapy in patients treated with sunitinib or sorafenib: a cohort study. | European journal of cancer (Oxford, England : 1990) 20120501 |
| Bisphosphonates combined with sunitinib may improve the response rate, progression free survival and overall survival of patients with bone metastases from renal cell carcinoma. | European journal of cancer (Oxford, England : 1990) 20120501 |
| The effect of sunitinib on primary renal cell carcinoma and facilitation of subsequent surgery. | The Journal of urology 20120501 |
| Synthesis and evaluation of 2-[2-(phenylthiomethyl)-1H-benzo[d] imidazol-1-yl)acetohydrazide derivatives as antitumor agents. | Bioorganic & medicinal chemistry letters 20120501 |
| Semaphorin 3A overcomes cancer hypoxia and metastatic dissemination induced by antiangiogenic treatment in mice. | The Journal of clinical investigation 20120501 |
| Off-label use of sunitinib in patients with advanced, epithelial thyroid cancer: a retrospective analysis. | Recent patents on endocrine, metabolic & immune drug discovery 20120501 |
| Presurgical treatment with sunitinib for renal cell carcinoma with a level III/IV vena cava tumour thrombus. | Anticancer research 20120501 |
| Survival of a patient with anaplastic thyroid cancer following intensity-modulated radiotherapy and sunitinib--a case report. | Anticancer research 20120501 |
| [Metastatic apocrine adenocarcinoma of the penis: cytostatic therapy]. | Aktuelle Urologie 20120501 |
| Efficacy and safety of sunitinib in Chinese patients with imatinib-resistant or -intolerant gastrointestinal stromal tumors. | Future oncology (London, England) 20120501 |
| Sunitinib and pancreatic neuroendocrine tumours. More assessment needed. | Prescrire international 20120501 |
| Discovery of the novel potent and selective FLT3 inhibitor 1-{5-[7-(3- morpholinopropoxy)quinazolin-4-ylthio]-[1,3,4]thiadiazol-2-yl}-3-p-tolylurea and its anti-acute myeloid leukemia (AML) activities in vitro and in vivo. | Journal of medicinal chemistry 20120426 |
| Randomised phase II trial of docetaxel and sunitinib in patients with metastatic gastric cancer who were previously treated with fluoropyrimidine and platinum. | British journal of cancer 20120424 |
| Randomized phase II trial of sunitinib on an intermittent versus continuous dosing schedule as first-line therapy for advanced renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120420 |
| Consequence of dose scheduling of sunitinib on host immune response elements and vaccine combination therapy. | International journal of cancer 20120415 |
| Analyzing the pivotal trial that compared sunitinib and IFN-α in renal cell carcinoma, using a method that assesses tumor regression and growth. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120415 |
| Radioiodinated sunitinib as a potential radiotracer for imaging angiogenesis-radiosynthesis and first radiopharmacological evaluation of 5-[125I]Iodo-sunitinib. | Bioorganic & medicinal chemistry letters 20120415 |
| Feasibility study of two schedules of sunitinib in combination with pemetrexed in patients with advanced solid tumors. | Investigational new drugs 20120401 |
| Sunitinib as a second-line therapy for advanced GISTs after failure of imatinib: relationship between efficacy and tumor genotype in Korean patients. | Investigational new drugs 20120401 |
| A phase II study of 2-methoxyestradiol nanocrystal colloidal dispersion alone and in combination with sunitinib malate in patients with metastatic renal cell carcinoma progressing on sunitinib malate. | Investigational new drugs 20120401 |
| Association of VEGF and VEGFR2 single nucleotide polymorphisms with hypertension and clinical outcome in metastatic clear cell renal cell carcinoma patients treated with sunitinib. | Cancer 20120401 |
| Combination of targeted agents in metastatic renal cell carcinoma: a path forward or a dead-end street? | Cancer 20120401 |
| Phase 1 trial of everolimus plus sunitinib in patients with metastatic renal cell carcinoma. | Cancer 20120401 |
| Sunitinib-induced nephrotic syndrome and irreversible renal dysfunction. | Clinical and experimental nephrology 20120401 |
| Sporadic CNS hemangioblastomatosis, response to sunitinib and secondary polycythemia. | Journal of neuro-oncology 20120401 |
| Evaluation of nilotinib in advanced GIST previously treated with imatinib and sunitinib. | Cancer chemotherapy and pharmacology 20120401 |
| Tolerability and pharmacokinetic profile of a sunitinib powder formulation in pediatric patients with refractory solid tumors: a Children's Oncology Group study. | Cancer chemotherapy and pharmacology 20120401 |
| Efficacy and safety of vascular endothelial growth factor receptor tyrosine kinase inhibitors in patients with metastatic renal cell carcinoma and poor risk features. | Journal of cancer research and clinical oncology 20120401 |
| P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) restrict brain accumulation of the active sunitinib metabolite N-desethyl sunitinib. | The Journal of pharmacology and experimental therapeutics 20120401 |
| Impact of sunitinib treatment on blood glucose levels in patients with metastatic renal cell carcinoma. | Japanese journal of clinical oncology 20120401 |
| New strategies for advanced neuroendocrine tumors in the era of targeted therapy. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120401 |
| Intracranial metastasis from pediatric GI stromal tumor. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120401 |
| Sunitinib plus paclitaxel in patients with advanced esophageal cancer: a phase II study from the Hoosier Oncology Group. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20120401 |
| Cutaneous side effects associated with sunitinib: an analysis of 8 cases. | International journal of clinical pharmacy 20120401 |
| The addition of Sunitinib to radiation delays tumor growth in a murine model of glioblastoma. | Neurological research 20120401 |
| Tyrosine kinase receptor inhibitor-targeted combined chemotherapy for metastatic bladder cancer. | The Kaohsiung journal of medical sciences 20120401 |
| Topical psoralen plus UV-A therapy for tyrosine kinase inhibitor-induced hand-foot syndrome. | Archives of dermatology 20120401 |
| First-line treatment of advanced breast cancer with sunitinib in combination with docetaxel versus docetaxel alone: results of a prospective, randomized phase III study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120320 |
| Sunitinib induces apoptosis in pheochromocytoma tumor cells by inhibiting VEGFR2/Akt/mTOR/S6K1 pathways through modulation of Bcl-2 and BAD. | American journal of physiology. Endocrinology and metabolism 20120315 |
| Meta-analysis of randomized controlled trials for the incidence and risk of treatment-related mortality in patients with cancer treated with vascular endothelial growth factor tyrosine kinase inhibitors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120310 |
| Three cases of severe ulcerative esophagitis induced by SUTENT®. | Journal of gastrointestinal cancer 20120301 |
| Could thyroid dysfunction influence outcome in sunitinib-treated metastatic renal cell carcinoma? | Annals of oncology : official journal of the European Society for Medical Oncology 20120301 |
| Sunitinib in combination with docetaxel and prednisone in chemotherapy-naive patients with metastatic, castration-resistant prostate cancer: a phase 1/2 clinical trial. | Annals of oncology : official journal of the European Society for Medical Oncology 20120301 |
| Determining the optimal dose and schedule of sunitinib: some answers, more questions. | Cancer 20120301 |
| Phase II trial of continuous once-daily dosing of sunitinib as first-line treatment in patients with metastatic renal cell carcinoma. | Cancer 20120301 |
| A phase I dose-escalation and pharmacokinetic study of sunitinib in combination with pemetrexed in patients with advanced solid malignancies, with an expanded cohort in non-small cell lung cancer. | Cancer chemotherapy and pharmacology 20120301 |
| RhoB mediates antitumor synergy of combined ixabepilone and sunitinib in human ovarian serous cancer. | Gynecologic oncology 20120301 |
| [Renal tolerance of targeted therapies]. | Bulletin du cancer 20120301 |
| Small intestine gastrointestinal stromal tumors. | Current opinion in gastroenterology 20120301 |
| Pharmacokinetics, distribution, and metabolism of [14C]sunitinib in rats, monkeys, and humans. | Drug metabolism and disposition: the biological fate of chemicals 20120301 |
| Alveolar soft part sarcoma in childhood: is Sunitinib-Sutent® treatment an effective approach? | Pediatric blood & cancer 20120301 |
| Sunitinib therapy for melanoma patients with KIT mutations. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120301 |
| Sunitinib: the first to arrive at first-line metastatic renal cell carcinoma. | Advances in therapy 20120301 |
| Phase I study of sunitinib plus modified FOLFOX6 in Japanese patients with treatment-naive colorectal cancer. | Anticancer research 20120301 |
| [Possibilities for inhibiting tumor-induced angiogenesis: results with multi-target tyrosine kinase inhibitors]. | Magyar onkologia 20120301 |
| [Resistance and treatment strategy of gastrointestinal stromal tumor target therapy]. | Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20120301 |
| Drug-induced palate osteonecrosis following nasal surgery. | The Israel Medical Association journal : IMAJ 20120301 |
| Sunitinib related osteonecrosis of jaw: a case report. | Oral surgery, oral medicine, oral pathology and oral radiology 20120301 |
| Serum 20S proteasome is elevated in patients with renal cell carcinoma and associated with poor prognosis. | British journal of cancer 20120227 |
| Long-term exposure of gastrointestinal stromal tumor cells to sunitinib induces epigenetic silencing of the PTEN gene. | International journal of cancer 20120215 |
| Inhibition of activated receptor tyrosine kinases by Sunitinib induces growth arrest and sensitizes melanoma cells to Bortezomib by blocking Akt pathway. | International journal of cancer 20120215 |
| Progression-free and overall survival in patients with relapsed/refractory germ cell tumors treated with single-agent chemotherapy: endpoints for clinical trial design. | Cancer 20120215 |
| Angiogenesis inhibitors identified by cell-based high-throughput screening: synthesis, structure-activity relationships and biological evaluation of 3-[(E)-styryl]benzamides that specifically inhibit endothelial cell proliferation. | Bioorganic & medicinal chemistry 20120215 |
| Baseline quality of life as a prognostic survival tool in patients receiving sunitinib for metastatic renal cell carcinoma. | British journal of cancer 20120214 |
| Second-line treatment for renal cell cancer. | British journal of cancer 20120214 |
| Treatment of patients with advanced neurofibromatosis type 2 with novel molecularly targeted therapies: from bench to bedside. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120210 |
| Complete remission with tyrosine kinase inhibitors in renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120210 |
| Phase II trial of sunitinib in patients with metastatic non-clear cell renal cell carcinoma. | Investigational new drugs 20120201 |
| Antitumor effect of sunitinib against skeletal metastatic renal cell carcinoma through inhibition of osteoclast function. | International journal of cancer 20120201 |
| Sunitinib followed by sorafenib or vice versa for metastatic renal cell carcinoma--data from the Czech registry. | Annals of oncology : official journal of the European Society for Medical Oncology 20120201 |
| [KIT and KIT: from biology to clinical use]. | Bulletin du cancer 20120201 |
| Dramatic reduction in tumor burden with neoadjuvant sunitinib prior to bilateral nephron-sparing surgery. | Urology 20120201 |
| Recurrent anaplastic meningioma treated by sunitinib based on results from quantitative proteomics. | Neuropathology and applied neurobiology 20120201 |
| Anti-angiogenic therapy: concept to clinic. | Microcirculation (New York, N.Y. : 1994) 20120201 |
| Sunitinib exerts only limited effects on the proliferation and differentiation of anaplastic thyroid cancer cells. | Thyroid : official journal of the American Thyroid Association 20120201 |
| Genital and inguinal cutaneous toxicity in male and female patients treated with sunitinib. | International journal of dermatology 20120201 |
| Inhibition of neuroblastoma cell proliferation with omega-3 fatty acids and treatment of a murine model of human neuroblastoma using a diet enriched with omega-3 fatty acids in combination with sunitinib. | Pediatric research 20120201 |
| Metastatic renal cell carcinoma treated sequentially with multiple VEGF receptor-targeted inhibitors--a case report. | Anticancer research 20120201 |
| Complete pathological response after sequential therapy with sunitinib and radiotherapy for metastatic clear cell renal carcinoma. | Anticancer research 20120201 |
| [Urgent patient admission to Working Group for Urological Oncology (AUO) studies on metastasized renal cell carcinoma needed: prospective randomized multicenter phase II study on resection of pulmonary metastases in clear cell renal cell carcinoma ± adjuvant sunitinib therapy over 1 year (SMAT - AN 20/04 of the AUO)]. | Der Urologe. Ausg. A 20120201 |
| Efficacy of Tie2 receptor antagonism in angiosarcoma. | Neoplasia (New York, N.Y.) 20120201 |
| Gingival bleeding and jaw bone necrosis in patients with metastatic renal cell carcinoma receiving sunitinib: report of 2 cases with clinical implications. | Oral surgery, oral medicine, oral pathology and oral radiology 20120201 |
| Structural and functional analysis of KIT gene encoding receptor tyrosine kinase and its interaction with sunitinib and HDAC inhibitors: an in silico approach. | Pakistan journal of biological sciences : PJBS 20120201 |
| VX-322: a novel dual receptor tyrosine kinase inhibitor for the treatment of acute myelogenous leukemia. | Journal of medicinal chemistry 20120126 |
| Targeted therapies for renal cell carcinoma: review of adverse event management strategies. | Journal of the National Cancer Institute 20120118 |
| Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway. | Cancer cell 20120117 |
| N⁴-Aryl-6-substitutedphenylmethyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines as receptor tyrosine kinase inhibitors. | Bioorganic & medicinal chemistry 20120115 |
| An update on targeted therapy in metastatic renal cell carcinoma. | Urologic oncology 20120101 |
| Treatment of multidrug resistant advanced alveolar soft part sarcoma with sunitinib. | American journal of therapeutics 20120101 |
| Feasibility and effects of high-dose hypofractionated radiation therapy and simultaneous multi-kinase inhibition with sunitinib in progressive metastatic renal cell cancer. | Urologic oncology 20120101 |
| Brain accumulation of sunitinib is restricted by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and can be enhanced by oral elacridar and sunitinib coadministration. | International journal of cancer 20120101 |
| A phase I study of sunitinib in combination with FOLFIRI in patients with untreated metastatic colorectal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20120101 |
| Hypertension as a predictive factor for survival outcomes in patients with metastatic renal cell carcinoma treated with sunitinib after progression on cytokines. | Kidney & blood pressure research 20120101 |
| Characterization of kinase inhibitors using different phosphorylation states of colony stimulating factor-1 receptor tyrosine kinase. | Journal of biochemistry 20120101 |
| Regression of established hepatocellular carcinoma is induced by chemoimmunotherapy in an orthotopic murine model. | Hepatology (Baltimore, Md.) 20120101 |
| Tyrosine kinase inhibitor sunitinib relieves systemic and oral antigen-induced anaphylaxes in mice. | Allergy 20120101 |
| The association of pre-treatment neutrophil to lymphocyte ratio with response rate, progression free survival and overall survival of patients treated with sunitinib for metastatic renal cell carcinoma. | European journal of cancer (Oxford, England : 1990) 20120101 |
| Tyrosine kinase inhibitors noncompetitively inhibit MCT8-mediated iodothyronine transport. | The Journal of clinical endocrinology and metabolism 20120101 |
| Gastrointestinal stromal tumors of the stomach. | Surgical oncology clinics of North America 20120101 |
| Sunitinib-induced systemic vasoconstriction in swine is endothelin mediated and does not involve nitric oxide or oxidative stress. | Hypertension (Dallas, Tex. : 1979) 20120101 |
| A phase II study of sunitinib as a second-line treatment in advanced biliary tract carcinoma: a multicentre, multinational study. | European journal of cancer (Oxford, England : 1990) 20120101 |
| An adaptive group sequential phase II design to compare treatments for survival endpoints in rare patient entities. | Journal of biopharmaceutical statistics 20120101 |
| Targeting of a platinum-bound sunitinib analog to renal proximal tubular cells. | International journal of nanomedicine 20120101 |
| Steve Jobs's cancer. Pancreatic neuroendocrine tumors are becoming more common (the bad news) and also more treatable (the good news). | Harvard health letter 20120101 |
| Neoadjuvant use of sunitinib in locally advanced GIST with intolerance to imatinib. | Chemotherapy 20120101 |
| The outcome and predictive factors of sunitinib therapy in advanced gastrointestinal stromal tumors (GIST) after imatinib failure - one institution study. | BMC cancer 20120101 |
| Sunitinib malate. | Profiles of drug substances, excipients, and related methodology 20120101 |
| Early assessment by FDG-PET/CT of patients with advanced renal cell carcinoma treated with tyrosine kinase inhibitors is predictive of disease course. | BMC cancer 20120101 |
| Sunitinib-induced autoimmune thyroiditis in a patient with metastatic renal cell carcinoma: a case report. | Chemotherapy 20120101 |
| Performing cytoreductive nephrectomy following targeted sunitinib therapy for metastatic renal cell carcinoma: a surgical perspective. | Urologia internationalis 20120101 |
| Current management of gastrointestinal stromal tumors--a comprehensive review. | International journal of surgery (London, England) 20120101 |
| Sunitinib treatment for refractory malignant pheochromocytoma. | Neuro endocrinology letters 20120101 |
| A pooled analysis of sequential therapies with sorafenib and sunitinib in metastatic renal cell carcinoma. | Oncology 20120101 |
| Surgery after treatment with imatinib and/or sunitinib in patients with metastasized gastrointestinal stromal tumors: is it worthwhile? | World journal of surgical oncology 20120101 |
| Epithelioid hemangioendothelioma of the kidney treated with sunitinib. | Onkologie 20120101 |
| Evaluation of poly-mechanistic antiangiogenic combinations to enhance cytotoxic therapy response in pancreatic cancer. | PloS one 20120101 |
| Chronic VEGF blockade worsens glomerular injury in the remnant kidney model. | PloS one 20120101 |
| Does sunitinib-induced hypothyroidism play a role in the activity of sunitinib in metastatic renal cell carcinoma? | Chemotherapy 20120101 |
| Phase II trial of concurrent sunitinib and image-guided radiotherapy for oligometastases. | PloS one 20120101 |
| Current status and perspectives of targeted therapy in well-differentiated neuroendocrine tumors. | Oncology 20120101 |
| Sunitinib-sensitive suicidal erythrocyte death. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101 |
| Sunitinib and everolimus in pancreatic neuroendocrine tumors. | Tumori 20120101 |
| Severe perirenal hematoma in a patient with a single kidney treated with sunitinib for metastatic pancreatic neuroendocrine tumor. | Journal of cancer research and therapeutics 20120101 |
| Sunitinib in patients with cisplatin-refractory germ cell tumors. | Onkologie 20120101 |
| The multi-targeted kinase inhibitor sunitinib induces apoptosis in colon cancer cells via PUMA. | PloS one 20120101 |
| Hypothyroidism during treatment with tyrosine kinase inhibitors. | Endokrynologia Polska 20120101 |
| Polymorphisms to predict outcome to the tyrosine kinase inhibitors gefitinib, erlotinib, sorafenib and sunitinib. | Current topics in medicinal chemistry 20120101 |
| Physiology and pharmacology of nonbisphosphonate drugs implicated in osteonecrosis of the jaw. | Journal (Canadian Dental Association) 20120101 |
| Myeloid-derived suppressor cells adhere to physiologic STAT3- vs STAT5-dependent hematopoietic programming, establishing diverse tumor-mediated mechanisms of immunologic escape. | Immunological investigations 20120101 |
| The erythropoietin/erythropoietin receptor signaling pathway promotes growth and invasion abilities in human renal carcinoma cells. | PloS one 20120101 |
| Evaluation of tyrosine kinase inhibitor combinations for glioblastoma therapy. | PloS one 20120101 |
| A phase 1b trial of the combination of the antiangiogenic agent sunitinib and radiation therapy for patients with primary and metastatic central nervous system malignancies. | Cancer 20111215 |
| Pharmacodynamic study using FLT PET/CT in patients with renal cell cancer and other solid malignancies treated with sunitinib malate. | Clinical cancer research : an official journal of the American Association for Cancer Research 20111215 |
| A novel preclinical strategy for identifying cardiotoxic kinase inhibitors and mechanisms of cardiotoxicity. | Circulation research 20111209 |
| Potential pitfalls of crossover and thoughts on iniparib in triple-negative breast cancer. | Journal of the National Cancer Institute 20111207 |
| Severe clinical toxicities are correlated with survival in patients with advanced renal cell carcinoma treated with sunitinib and sorafenib. | British journal of cancer 20111206 |
| Phase II study of sunitinib as second-line treatment for advanced gastric cancer. | Investigational new drugs 20111201 |
| Preclinical evaluation of sunitinib as single agent or in combination with chemotherapy in nasopharyngeal carcinoma. | Investigational new drugs 20111201 |
| Long-term stable disease in metastatic renal cell carcinoma: sorafenib sequenced to sunitinib and everolimus: a case study. | Medical oncology (Northwood, London, England) 20111201 |
| VEGF pathway inhibition by anticancer agent sunitinib and susceptibility to atherosclerosis plaque disruption. | Investigational new drugs 20111201 |
| Long-term response with everolimus for metastatic renal cell carcinoma refractory to sunitinib. | Medical oncology (Northwood, London, England) 20111201 |
| Bilateral papilledema on sunitinib therapy for advanced renal cell carcinoma. | Medical oncology (Northwood, London, England) 20111201 |
| Sunitinib-induced severe hypothyroidism with cardiac compromise. | Medical oncology (Northwood, London, England) 20111201 |
| Hypothyroidism correlates with a better prognosis in metastatic renal cancer patients treated with sorafenib or sunitinib. | World journal of urology 20111201 |
| Monitoring the effect of targeted therapies in a gastrointestinal stromal tumor xenograft using a clinical PET/CT. | Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20111201 |
| Management of recurrent gastrointestinal stromal tumors. | Journal of surgical oncology 20111201 |
| Surgical intervention for imatinib and sunitinib-resistant gastrointestinal stromal tumors. | International journal of clinical oncology 20111201 |
| Preclinical and clinical activity of sunitinib in patients with cisplatin-refractory or multiply relapsed germ cell tumors: a Canadian Urologic Oncology Group/German Testicular Cancer Study Group cooperative study. | Annals of oncology : official journal of the European Society for Medical Oncology 20111201 |
| Phase II study of sunitinib as first-line treatment of urothelial cancer patients ineligible to receive cisplatin-based chemotherapy: baseline interleukin-8 and tumor contrast enhancement as potential predictive factors of activity. | Annals of oncology : official journal of the European Society for Medical Oncology 20111201 |
| Phase II study of sunitinib as maintenance therapy in patients with locally advanced or metastatic non-small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20111201 |
| Phase I study of sunitinib and irinotecan for patients with recurrent malignant glioma. | Journal of neuro-oncology 20111201 |
| Early primary tumor size reduction is an independent predictor of improved overall survival in metastatic renal cell carcinoma patients treated with sunitinib. | European urology 20111201 |
| Sequence therapy in patients with metastatic renal cell carcinoma: comparison of common targeted treatment options following failure of receptor tyrosine kinase inhibitors. | European urology 20111201 |
| Heart failure associated with sunitinib: lessons learned from animal models. | Current hypertension reports 20111201 |
| Tumor kinase activity in locally advanced rectal cancer: angiogenic signaling and early systemic dissemination. | Angiogenesis 20111201 |
| Sunitinib, hypertension, and heart failure: a model for kinase inhibitor-mediated cardiotoxicity. | Current hypertension reports 20111201 |
| Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance. | Clinical cancer research : an official journal of the American Association for Cancer Research 20111201 |
| Response rates and adverse effects of continuous once-daily sunitinib in patients with advanced renal cell carcinoma: a single-center study in Turkey. | Japanese journal of clinical oncology 20111201 |
| Synthesis and biological evaluation of 2-indolinone derivatives as potential antitumor agents. | European journal of medicinal chemistry 20111201 |
| Survivin expression and its potential clinical significance in gastrointestinal stromal sarcoma. | International immunopharmacology 20111201 |
| Advanced or metastatic gastrointestinal stromal tumors: systemic treatment options. | Journal of surgical oncology 20111201 |
| Systemic therapy for advanced gastrointestinal stromal tumors: beyond imatinib. | Journal of surgical oncology 20111201 |
| Phase 2 trial of linifanib (ABT-869) in patients with advanced renal cell cancer after sunitinib failure. | European journal of cancer (Oxford, England : 1990) 20111201 |
| Tyrosine kinase inhibitor-induced hypothyroidism: incidence, etiology, and management. | Targeted oncology 20111201 |
| Pilot trial of sunitinib therapy in patients with von Hippel-Lindau disease. | Annals of oncology : official journal of the European Society for Medical Oncology 20111201 |
| Sunitinib for advanced pancreatic neuroendocrine tumors. | Expert review of anticancer therapy 20111201 |
| Cost-effectiveness evaluation of sunitinib as first-line targeted therapy for metastatic renal cell carcinoma in Spain. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20111201 |
| New insights into molecular mechanisms of sunitinib-associated side effects. | Molecular cancer therapeutics 20111201 |
| VEGF pathway-targeted therapy for advanced renal cell carcinoma: a meta-analysis of randomized controlled trials. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20111201 |
| Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
| Correlation between IDH1 gene mutation status and survival of patients treated for recurrent glioma. | Anticancer research 20111201 |
| Sorafenib: muscle wasting. | Prescrire international 20111201 |
| Novel therapies for metastatic castrate-resistant prostate cancer. | Journal of the National Cancer Institute 20111116 |
| Use of human stem cell derived cardiomyocytes to examine sunitinib mediated cardiotoxicity and electrophysiological alterations. | Toxicology and applied pharmacology 20111115 |
| Targeting PIM kinase enhances the activity of sunitinib in renal cell carcinoma. | British journal of cancer 20111108 |
| Sunitinib facilitates the activation and recruitment of therapeutic anti-tumor immunity in concert with specific vaccination. | International journal of cancer 20111101 |
| Suppressing effects of sunitinib on allergic rhinitis: previously undefined side effects with therapeutic potential. | Journal of clinical pharmacology 20111101 |
| A USA registry of gastrointestinal stromal tumor patients: changes in practice over time and differences between community and academic practices. | Annals of oncology : official journal of the European Society for Medical Oncology 20111101 |
| Impact of tyrosine kinase inhibitors on the incidence of brain metastasis in metastatic renal cell carcinoma. | Cancer 20111101 |
| Experience in the use of sunitinib given as a single agent in metastatic chemoresistant and castration-resistant prostate cancer patients. | Expert opinion on pharmacotherapy 20111101 |
| Biomarkers to predict response to sunitinib therapy and prognosis in metastatic renal cell cancer. | Cancer science 20111101 |
| Sunitinib inhibits tumor vascularity and growth but does not affect Akt and ERK phosphorylation in xenograft tumors. | Oncology reports 20111101 |
| Neurosensory retinal detachment due to sunitinib treatment. | Eye (London, England) 20111101 |
| Drug interactions with mitotane by induction of CYP3A4 metabolism in the clinical management of adrenocortical carcinoma. | Clinical endocrinology 20111101 |
| Emerging therapies targeting tumor vasculature in multiple myeloma and other hematologic and solid malignancies. | Current cancer drug targets 20111101 |
| BRN-103, a novel nicotinamide derivative, inhibits VEGF-induced angiogenesis and proliferation in human umbilical vein endothelial cells. | Bioorganic & medicinal chemistry letters 20111101 |
| Sunitinib-induced nephrotic syndrome in association with drug response in a patient with Xp11.2 translocation renal cell carcinoma. | Japanese journal of clinical oncology 20111101 |
| Clinical experience with antiangiogenic therapy in leukemia. | Current cancer drug targets 20111101 |
| Brief report: a phase II study of sunitinib in malignant pleural mesothelioma. the NCIC Clinical Trials Group. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20111101 |
| Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: a multicentre, observational, prospective study. | The Lancet. Oncology 20111101 |
| Targeted therapy for patients with renal-cell carcinoma. | The Lancet. Oncology 20111101 |
| Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity. | Nature biotechnology 20111101 |
| Sunitinib-induced asthenia: from molecular basis to clinical relief. | Cancer biology & therapy 20111101 |
| Tyrosine kinase inhibitors for metastatic renal cell carcinoma. | Drug and therapeutics bulletin 20111101 |
| [Advanced sarcomatoid renal cell carcinoma effectively treated with sunitinib: report of a case]. | Hinyokika kiyo. Acta urologica Japonica 20111101 |
| [Twenty-one-year survival case of rectal GIST treated with combined therapies]. | Gan to kagaku ryoho. Cancer & chemotherapy 20111101 |
| [A case of gastrointestinal stromal tumor (GIST) successfully treated with resection after a long-term control medication by molecular targeted drugs]. | Gan to kagaku ryoho. Cancer & chemotherapy 20111101 |
| Comprehensive analysis of kinase inhibitor selectivity. | Nature biotechnology 20111030 |
| Reversible cardiomyopathy associated with sunitinib and sorafenib. | The New England journal of medicine 20111027 |
| Phase II study of sunitinib malate, a multitargeted tyrosine kinase inhibitor in patients with relapsed or refractory soft tissue sarcomas. Focus on three prevalent histologies: leiomyosarcoma, liposarcoma and malignant fibrous histiocytoma. | International journal of cancer 20111015 |
| Phase 2 study of nilotinib as third-line therapy for patients with gastrointestinal stromal tumor. | Cancer 20111015 |
| Antiangiogenic agent sunitinib transiently increases tumor oxygenation and suppresses cycling hypoxia. | Cancer research 20111015 |
| Pneumatosis intestinalis associated with treatment of cancer patients with the vascular growth factor receptor tyrosine kinase inhibitors sorafenib and sunitinib. | Investigational new drugs 20111001 |
| Blue toe syndrome and sunitinib. | International journal of clinical oncology 20111001 |
| A case study of metastatic Xp11.2 translocation renal cell carcinoma effectively treated with sunitinib. | International journal of clinical oncology 20111001 |
| Efficacy and toxicity of sunitinib in patients with metastatic renal cell carcinoma with severe renal impairment or on haemodialysis. | BJU international 20111001 |
| Addition of gemcitabine at the time of sunitinib resistance in metastatic renal cell cancer. | BJU international 20111001 |
| Efficacy and toxicity of sunitinib in patients with metastatic renal cell carcinoma with severe renal impairment or on haemodialysis. | BJU international 20111001 |
| Sequential use of sorafenib and sunitinib in advanced renal-cell carcinoma (RCC): an Italian multicentre retrospective analysis of 189 patient cases. | BJU international 20111001 |
| Efficacy of re-challenging metastatic renal cell carcinoma with mTOR inhibitors. | Acta oncologica (Stockholm, Sweden) 20111001 |
| Inhibition of fms-like tyrosine kinase 3 alleviates experimental arthritis by reducing formation of dendritic cells and antigen presentation. | Journal of leukocyte biology 20111001 |
| A phase II study of presurgical sunitinib in patients with metastatic clear-cell renal carcinoma and the primary tumor in situ. | Urology 20111001 |
| Sunitinib-induced hypothyroidism is due to induction of type 3 deiodinase activity and thyroidal capillary regression. | The Journal of clinical endocrinology and metabolism 20111001 |
| The heat shock protein 90 inhibitor IPI-504 induces KIT degradation, tumor shrinkage, and cell proliferation arrest in xenograft models of gastrointestinal stromal tumors. | Molecular cancer therapeutics 20111001 |
| Comparing the efficacy of sunitinib with sorafenib in xenograft models of human hepatocellular carcinoma: mechanistic explanation. | Current cancer drug targets 20111001 |
| Flare up of symptoms after discontinuation of sunitinib in patient with lung cancer. | Acta oncologica (Stockholm, Sweden) 20111001 |
| Synthesis and pharmacological evaluations of novel 2H-benzo[b][1,4]oxazin-3(4H)-one derivatives as a new class of anti-cancer agents. | European journal of medicinal chemistry 20111001 |
| Role of biological targeted therapies in gastroenteropancreatic neuroendocrine tumours. | Endocrine 20111001 |
| Targeted systemic radiotherapy with scVEGF/177Lu leads to sustained disruption of the tumor vasculature and intratumoral apoptosis. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20111001 |
| New target therapies for patients with neuroendocrine tumors of the pancreas. | Expert review of gastroenterology & hepatology 20111001 |
| [Renal carcinoma and fatigue: which challenge in the era of antiangiogenic drugs?]. | Bulletin du cancer 20111001 |
| Sunitinib: in advanced, well differentiated pancreatic neuroendocrine tumors. | BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20111001 |
| Sunitinib-induced hyperammonemic encephalopathy in gastrointestinal stromal tumors. | The Annals of pharmacotherapy 20111001 |
| Case report of pneumatosis intestinalis secondary to sunitinib treatment for refractory gastrointestinal stromal tumor. | Anticancer research 20111001 |
| Sunitinib re-challenge in metastatic renal cell carcinoma treated sequentially with tyrosine kinase inhibitors and everolimus. | Anticancer research 20111001 |
| Gastrointestinal stromal tumor: advances in diagnosis and management. | Archives of pathology & laboratory medicine 20111001 |
| Interleukin-6: a potential biomarker of resistance to multitargeted receptor tyrosine kinase inhibitors in castration-resistant prostate cancer. | Urology 20111001 |
| [Dermatologic side effects induced by new angiogenesis inhibitors]. | Bulletin du cancer 20111001 |
| Determination of sunitinib and its active metabolite N-desethylsunitinib in sweat of a patient. | Journal of analytical toxicology 20111001 |
| Reappraising antiangiogenic therapy for breast cancer. | Breast (Edinburgh, Scotland) 20111001 |
| HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants. | PLoS genetics 20111001 |
| Circulating perivascular progenitors: a target of PDGFR inhibition. | International journal of cancer 20110915 |
| Sequential FDG-PET/CT as a biomarker of response to Sunitinib in metastatic clear cell renal cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110915 |
| Acne rosacea associated imatinib mesylate in a gastrointestinal stromal tumor patient. | Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20110901 |
| Effect of the tyrosine kinase inhibitors (sunitinib, sorafenib, dasatinib, and imatinib) on blood glucose levels in diabetic and nondiabetic patients in general clinical practice. | Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20110901 |
| Sunitinib in combination with paclitaxel plus carboplatin in patients with advanced solid tumors: phase I study results. | Cancer chemotherapy and pharmacology 20110901 |
| Simultaneous anti-angiogenic therapy and single-fraction radiosurgery in clinically relevant metastases from renal cell carcinoma. | BJU international 20110901 |
| Economic evaluation of new targeted therapies for the first-line treatment of patients with metastatic renal cell carcinoma. | BJU international 20110901 |
| Comparative pre-clinical evaluation of receptor tyrosine kinase inhibitors for the treatment of multiple myeloma. | Leukemia research 20110901 |
| [Metastatic renal cell cancer in Germany in 2010. Impact of different target therapies]. | Der Urologe. Ausg. A 20110901 |
| Complete response to sunitinib in a patient with relapsed irresectable renal cell carcinoma. | Anti-cancer drugs 20110901 |
| Angiotensin system inhibitors and outcome of sunitinib treatment in patients with metastatic renal cell carcinoma: a retrospective examination. | European journal of cancer (Oxford, England : 1990) 20110901 |
| The outcome of patients treated with sunitinib prior to planned nephrectomy in metastatic clear cell renal cancer. | European urology 20110901 |
| New therapeutic options for metastatic malignant insulinomas. | Clinical endocrinology 20110901 |
| Sunitinib prior to planned cytoreductive nephrectomy: is this the new litmus test for metastatic renal cell carcinoma? | European urology 20110901 |
| Sunitinib inhibits papillary thyroid carcinoma with RET/PTC rearrangement but not BRAF mutation. | Cancer biology & therapy 20110901 |
| Sunitinib-induced acute psychosis: case report. | Clinical genitourinary cancer 20110901 |
| The Novel HSP90 inhibitor, IPI-493, is highly effective in human gastrostrointestinal stromal tumor xenografts carrying heterogeneous KIT mutations. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110901 |
| Synergistic interaction between sunitinib and docetaxel is sequence dependent in human non-small lung cancer with EGFR TKIs-resistant mutation. | Journal of cancer research and clinical oncology 20110901 |
| Incidence and risk of congestive heart failure in patients with renal and nonrenal cell carcinoma treated with sunitinib. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110901 |
| VEGF expression is related to good response and long progression-free survival in gastrointestinal stromal tumor patients treated with Sunitinib. | Diagnostic molecular pathology : the American journal of surgical pathology, part B 20110901 |
| Antitumour activity of sunitinib in combination with gemcitabine in experimental pancreatic cancer. | HPB : the official journal of the International Hepato Pancreato Biliary Association 20110901 |
| Impact of sunitinib pharmacokinetic monitoring in a patient with metastatic renal cell carcinoma undergoing hemodialysis. | Annals of oncology : official journal of the European Society for Medical Oncology 20110901 |
| Renal carcinoma with (6;11)(p21;q12) translocation: report of an adult case. | Pathology international 20110901 |
| Everolimus and sunitinib: from mouse models to treatment of pancreatic neuroendocrine tumors. | Future oncology (London, England) 20110901 |
| Efficacy and safety of sunitinib in the treatment of metastatic renal cell carcinoma. | Chinese medical journal 20110901 |
| Response of ETV6-FLT3-positive myeloid/lymphoid neoplasm with eosinophilia to inhibitors of FMS-like tyrosine kinase 3. | Blood 20110825 |
| Prognostic model for survival in patients with metastatic renal cell carcinoma: results from the international kidney cancer working group. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110815 |
| Nilotinib in patients with GIST who failed imatinib and sunitinib: importance of prior surgery on drug bioavailability. | Cancer chemotherapy and pharmacology 20110801 |
| A decade of tyrosine kinase inhibitor therapy: Historical and current perspectives on targeted therapy for GIST. | Cancer treatment reviews 20110801 |
| Comparison of RECIST and Choi criteria for computed tomographic response evaluation in patients with advanced gastrointestinal stromal tumor treated with sunitinib. | Annals of oncology : official journal of the European Society for Medical Oncology 20110801 |
| Added value of molecular targeted agents in oncology. | Annals of oncology : official journal of the European Society for Medical Oncology 20110801 |
| Molecular mechanisms of drug resistance in tyrosine kinases cAbl and cKit. | Critical reviews in biochemistry and molecular biology 20110801 |
| Dynamic microbubble contrast-enhanced US to measure tumor response to targeted therapy: a proposed clinical protocol with results from renal cell carcinoma patients receiving antiangiogenic therapy. | Radiology 20110801 |
| Life-threatening hypoglycemia induced by a tyrosine kinase inhibitor in a patient with neuroendocrine tumor: a case report. | Diabetes research and clinical practice 20110801 |
| Antiangiogenic agents and endothelin antagonists in advanced castration resistant prostate cancer. | European journal of cancer (Oxford, England : 1990) 20110801 |
| Vasculatures in tumors growing from preirradiated tissues: formed by vasculogenesis and resistant to radiation and antiangiogenic therapy. | International journal of radiation oncology, biology, physics 20110801 |
| Design, synthesis and biological evaluation of novel 4-thiazolidinones containing indolin-2-one moiety as potential antitumor agent. | European journal of medicinal chemistry 20110801 |
| Sunitinib in urothelial cancer: clinical, pharmacokinetic, and immunohistochemical study of predictors of response. | European urology 20110801 |
| The vascular endothelial growth factor receptor inhibitor sunitinib causes a preeclampsia-like syndrome with activation of the endothelin system. | Hypertension (Dallas, Tex. : 1979) 20110801 |
| Phase I and pharmacokinetic study of sunitinib in pediatric patients with refractory solid tumors: a children's oncology group study. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110801 |
| The emerging role of sunitinib in the treatment of advanced epithelial thyroid cancer: our experience and review of literature. | Mini reviews in medicinal chemistry 20110801 |
| Arthrinins A-D: novel diterpenoids and further constituents from the sponge derived fungus Arthrinium sp. | Bioorganic & medicinal chemistry 20110801 |
| Systemic therapy for metastatic non-clear-cell renal cell carcinoma: recent progress and future directions. | Hematology/oncology clinics of North America 20110801 |
| FLT3 inhibition as therapy in acute myeloid leukemia: a record of trials and tribulations. | The oncologist 20110801 |
| Cost-effectiveness of sunitinib in metastatic renal cell carcinoma. | Expert review of pharmacoeconomics & outcomes research 20110801 |
| Complementary information from magnetic resonance imaging and (18)F-fluoromisonidazole positron emission tomography in the assessment of the response to an antiangiogenic treatment in a rat brain tumor model. | Nuclear medicine and biology 20110801 |
| Are all multi-targeted tyrosine kinase inhibitors created equal? An in vitro study of sunitinib and pazopanib in renal cell carcinoma cell lines. | The Canadian journal of urology 20110801 |
| [Gastrointestinal stromal tumour (GIST): current standards in multimodal management]. | Zentralblatt fur Chirurgie 20110801 |
| [Systemic treatment of renal cell carcinoma - recent update]. | Wiener medizinische Wochenschrift (1946) 20110801 |
| A shining light in the darkness for the treatment of pancreatic neuroendocrine tumors. | Cancer discovery 20110801 |
| Inhibition of RNase L and RNA-dependent protein kinase (PKR) by sunitinib impairs antiviral innate immunity. | The Journal of biological chemistry 20110729 |
| [Adverse effects of new oncologic therapies]. | Praxis 20110727 |
| Targeting lymphangiogenesis after islet transplantation prolongs islet allograft survival. | Transplantation 20110715 |
| Phase II study of sunitinib malate in patients with recurrent high-grade glioma. | Journal of neuro-oncology 20110701 |
| Myeloid derived suppressor cells in human diseases. | International immunopharmacology 20110701 |
| Sunitinib in advanced alveolar soft part sarcoma: evidence of a direct antitumor effect. | Annals of oncology : official journal of the European Society for Medical Oncology 20110701 |
| MDSC as a mechanism of tumor escape from sunitinib mediated anti-angiogenic therapy. | International immunopharmacology 20110701 |
| Sunitinib inhibits postoperative adhesions in a rabbit model. | Surgery 20110701 |
| Treatment of gastrointestinal stromal tumor after imatinib and sunitinib. | Current opinion in oncology 20110701 |
| Changes in tumor density in patients with advanced hepatocellular carcinoma treated with sunitinib. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110701 |
| The use of 24-h ambulatory blood pressure monitoring (ABPM) during the first cycle of sunitinib improves the diagnostic accuracy and management of hypertension in patients with advanced renal cancer. | European journal of cancer (Oxford, England : 1990) 20110701 |
| An open-label, multicentre biomarker-oriented AIO phase II trial of sunitinib for patients with chemo-refractory advanced gastric cancer. | European journal of cancer (Oxford, England : 1990) 20110701 |
| Treatment of tenosynovial giant cell tumor and pigmented villonodular synovitis. | Current opinion in oncology 20110701 |
| An adjusted indirect comparison of everolimus and sorafenib therapy in sunitinib-refractory metastatic renal cell carcinoma patients using repeated matched samples. | Expert opinion on pharmacotherapy 20110701 |
| Phase II study of sunitinib in patients with non-small cell lung cancer and irradiated brain metastases. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110701 |
| Temsirolimus and bevacizumab, or sunitinib, or interferon alfa and bevacizumab for patients with advanced renal cell carcinoma (TORAVA): a randomised phase 2 trial. | The Lancet. Oncology 20110701 |
| Metastatic renal cell carcinoma: relationship between initial metastasis hypoxia, change after 1 month's sunitinib, and therapeutic response: an 18F-fluoromisonidazole PET/CT study. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110701 |
| Cancer patients treated with sunitinib or sorafenib have sufficient antibody and cellular immune responses to warrant influenza vaccination. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110701 |
| [Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma]. | Aktuelle Urologie 20110701 |
| Irreversible Nek2 kinase inhibitors with cellular activity. | Journal of medicinal chemistry 20110623 |
| Response to sunitinib in an adult patient with rhabdoid renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110620 |
| A proof of concept phase II non-inferiority criterion. | Statistics in medicine 20110615 |
| Chemoresponse assay for evaluating response to sunitinib in primary cultures of breast cancer. | Cancer biology & therapy 20110615 |
| Sunitinib in pretreated advanced non-small-cell lung carcinoma: a primary result from Asian population. | Medical oncology (Northwood, London, England) 20110601 |
| Tubulocystic renal carcinoma: a clinical perspective. | World journal of urology 20110601 |
| Combined positron emission tomography/computed tomography in sunitinib therapy assessment of patients with metastatic renal cell carcinoma. | Clinical oncology (Royal College of Radiologists (Great Britain)) 20110601 |
| Response of renal lesions during systemic treatment with sunitinib in patients with metastatic renal cell carcinoma: a single center experience with 14 patients. | World journal of urology 20110601 |
| Hemorrhagic complications in a phase II study of sunitinib in patients of nasopharyngeal carcinoma who has previously received high-dose radiation. | Annals of oncology : official journal of the European Society for Medical Oncology 20110601 |
| Interaction of green tea polyphenol epigallocatechin-3-gallate with sunitinib: potential risk of diminished sunitinib bioavailability. | Journal of molecular medicine (Berlin, Germany) 20110601 |
| Mutational spectrum and therapy response of metastasized GIST in Central Switzerland - a population-based study. | European journal of cancer (Oxford, England : 1990) 20110601 |
| Response by Choi criteria to sunitinib plus octreotide LAR in a functional heavily pretreated advanced pancreatic neuroendocrine tumor. | Anti-cancer drugs 20110601 |
| The impact of targeted molecular therapies on the level of renal cell carcinoma vena caval tumor thrombus. | European urology 20110601 |
| Hemorrhage caused by antiangiogenic therapy within previously irradiated areas: expected consequence of tumor shrinkage or a warning for antiangiogenic agents combined to radiotherapy? | Annals of oncology : official journal of the European Society for Medical Oncology 20110601 |
| MVA-5T4-induced immune responses are an early marker of efficacy in renal cancer patients. | Cancer immunology, immunotherapy : CII 20110601 |
| Exposure-response relationships in patients with metastatic renal cell carcinoma receiving sunitinib: maintaining optimum efficacy in clinical practice. | Anti-cancer drugs 20110601 |
| Discovery, synthesis, and investigation of the antitumor activity of novel piperazinylpyrimidine derivatives. | European journal of medicinal chemistry 20110601 |
| Targeted caval cytoreduction: solid foundations or shifting sands? | European urology 20110601 |
| Sequential therapies with sorafenib and sunitinib in advanced or metastatic renal cell carcinoma. | World journal of urology 20110601 |
| The effects of four different tyrosine kinase inhibitors on medullary and papillary thyroid cancer cells. | The Journal of clinical endocrinology and metabolism 20110601 |
| Treatment of metastatic renal cell carcinoma and renal pelvic cancer. | Clinical and experimental nephrology 20110601 |
| [Gottron-like papules induced by sunitinib]. | Actas dermo-sifiliograficas 20110601 |
| Potent activity of ponatinib (AP24534) in models of FLT3-driven acute myeloid leukemia and other hematologic malignancies. | Molecular cancer therapeutics 20110601 |
| Phase II trial of sunitinib maintenance therapy after platinum-based chemotherapy in patients with extensive-stage small cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110601 |
| [New therapeutic options for advanced thyroid cancer]. | Deutsche medizinische Wochenschrift (1946) 20110601 |
| Targeting angiogenesis in esophagogastric adenocarcinoma. | The oncologist 20110601 |
| [Sunitinib as a second-line therapy for imatinib-resistant gastrointestinal stromal tumors]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110601 |
| Bevacizumab, sunitinib: osteonecrosis of the jaw. | Prescrire international 20110601 |
| Multikinase inhibitors in metastatic renal cell carcinoma: indirect comparison meta-analysis. | Clinical therapeutics 20110601 |
| Vatalanib for metastatic gastrointestinal stromal tumour (GIST) resistant to imatinib: final results of a phase II study. | British journal of cancer 20110524 |
| Synthesis and antitumor activity of 5-[1-(3-(dimethylamino)propyl)-5-halogenated-2-oxoindolin-(3Z)-ylidenemethyl]-2,4-dimethyl-1H-pyrrole-3-carboxamides. | Bioorganic & medicinal chemistry letters 20110515 |
| Advances in pancreatic neuroendocrine tumor treatment. | The New England journal of medicine 20110512 |
| Advances in pancreatic neuroendocrine tumor treatment. | The New England journal of medicine 20110512 |
| Advances in pancreatic neuroendocrine tumor treatment. | The New England journal of medicine 20110512 |
| Advances in pancreatic neuroendocrine tumor treatment. | The New England journal of medicine 20110512 |
| Hypertension as a biomarker of efficacy in patients with metastatic renal cell carcinoma treated with sunitinib. | Journal of the National Cancer Institute 20110504 |
| Sunitinib improves chemotherapeutic efficacy and ameliorates cisplatin-induced nephrotoxicity in experimental animals. | Cancer chemotherapy and pharmacology 20110501 |
| Evolving strategies for the treatment of hepatocellular carcinoma: from clinical-guided to molecularly-tailored therapeutic options. | Cancer treatment reviews 20110501 |
| Role of sorafenib and sunitinib in the induction of expressions of NKG2D ligands in nasopharyngeal carcinoma with high expression of ABCG2. | Journal of cancer research and clinical oncology 20110501 |
| Sunitinib for the treatment of metastatic renal cell carcinoma. | Cancer treatment reviews 20110501 |
| Lower limbs erosions induced by sunitinib. | Acta dermato-venereologica 20110501 |
| Epithelial-to-mesenchymal transition and acquired resistance to sunitinib in a patient with hepatocellular carcinoma. | Journal of hepatology 20110501 |
| Antiangiogenic tyrosine kinase inhibition related gastrointestinal perforations: a case report and literature review. | Angiogenesis 20110501 |
| Hypertension as predictor of sunitinib treatment outcome in metastatic renal cell carcinoma. | Acta oncologica (Stockholm, Sweden) 20110501 |
| The safety and efficacy of sunitinib before planned nephrectomy in metastatic clear cell renal cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20110501 |
| Sorafenib and sunitinib, two anticancer drugs, inhibit CYP3A4-mediated and activate CY3A5-mediated midazolam 1'-hydroxylation. | Drug metabolism and disposition: the biological fate of chemicals 20110501 |
| Comparison of four early posttherapy imaging changes (EPTIC; RECIST 1.0, tumor shrinkage, computed tomography tumor density, Choi criteria) in assessing outcome to vascular endothelial growth factor-targeted therapy in patients with advanced renal cell carcinoma. | European urology 20110501 |
| Targeted therapies: Good news for advanced-stage pancreatic neuroendocrine tumors. | Nature reviews. Clinical oncology 20110501 |
| Sunitinib in relapsed or refractory diffuse large B-cell lymphoma: a clinical and pharmacodynamic phase II multicenter study of the NCIC Clinical Trials Group. | Leukemia & lymphoma 20110501 |
| Long-term response and postsurgical complete remissions after treatment with sunitinib malate, an oral multitargeted receptor tyrosine kinase inhibitor, in patients with metastatic renal cell carcinoma. | Cancer investigation 20110501 |
| Reversible posterior leucoencephalopathy syndrome in an elderly male on sunitinib therapy. | British journal of clinical pharmacology 20110501 |
| Sunitinib in metastatic renal cell carcinoma: recommendations for management of noncardiovascular toxicities. | The oncologist 20110501 |
| Novel nephrotoxins. | Advances in chronic kidney disease 20110501 |
| [Evidence-based treatment of gastrointestinal stromal tumor (GIST) with tyrosine kinase inhibitors-imatinib and sunitinib]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110501 |
| [A case of imatinib-resistant GIST treated by sunitinib]. | Gan to kagaku ryoho. Cancer & chemotherapy 20110501 |
| [Indications and current development of new targeted therapies in pediatric oncology]. | Bulletin du cancer 20110501 |
| Phase I study of sunitinib and erlotinib in advanced nonsquamous non-small cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110501 |
| Sunitinib for Taiwanese patients with gastrointestinal stromal tumor after imatinib treatment failure or intolerance. | World journal of gastroenterology 20110428 |
| [Novelties in the treatment for advanced renal-cell cancer]. | Orvosi hetilap 20110424 |
| Recent studies show promise for treating rare pancreatic tumors. | Journal of the National Cancer Institute 20110420 |
| IL6-STAT3-HIF signaling and therapeutic response to the angiogenesis inhibitor sunitinib in ovarian clear cell cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110415 |
| Double-transduced MDCKII cells to study human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) interplay in drug transport across the blood-brain barrier. | Molecular pharmaceutics 20110404 |
| Metastatic collecting duct carcinoma of the kidney responded to sunitinib. | International journal of clinical oncology 20110401 |
| Negative impact of bone metastasis on outcome in clear-cell renal cell carcinoma treated with sunitinib. | Annals of oncology : official journal of the European Society for Medical Oncology 20110401 |
| Increased haematopoietic progenitor cells are associated with poor outcome in patients with metastatic renal cancer treated with sunitinib. | Annals of oncology : official journal of the European Society for Medical Oncology 20110401 |
| Predicting and preventing cardiotoxicity in the era of breast cancer targeted therapies. Novel molecular tools for clinical issues. | Breast (Edinburgh, Scotland) 20110401 |
| Development and characterization of clinically relevant tumor models from patients with renal cell carcinoma. | European urology 20110401 |
| Mitotane has a strong and a durable inducing effect on CYP3A4 activity. | European journal of endocrinology 20110401 |
| Pyoderma gangrenosum with the use of sunitinib. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110401 |
| Initial patterns of care with oral targeted therapies for patients with renal cell carcinoma. | Urology 20110401 |
| Neoadjuvant systemic therapy or early cystectomy? Single-center analysis of outcomes after therapy for patients with clinically localized micropapillary urothelial carcinoma of the bladder. | Urology 20110401 |
| Tumor size is a potential predictor of response to tyrosine kinase inhibitors in renal cell cancer. | Urology 20110401 |
| Identification of soluble candidate biomarkers of therapeutic response to sunitinib in medullary thyroid carcinoma in preclinical models. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110401 |
| Effects of targeting the VEGF and PDGF pathways in diffuse orthotopic glioma models. | The Journal of pathology 20110401 |
| Development and validation of a liquid chromatography/tandem mass spectrometry procedure for the quantification of sunitinib (SU11248) and its active metabolite, N-desethyl sunitinib (SU12662), in human plasma: application to an explorative study. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110401 |
| Two drug interaction studies of sirolimus in combination with sorafenib or sunitinib in patients with advanced malignancies. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110401 |
| [Treatment of metastatic renal cell carcinoma]. | Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20110401 |
| Sunitinib suppresses tumor growth and metastases in a highly metastatic mouse mammary cancer model. | Anticancer research 20110401 |
| Sunitinib plus paclitaxel versus bevacizumab plus paclitaxel for first-line treatment of patients with advanced breast cancer: a phase III, randomized, open-label trial. | Clinical breast cancer 20110401 |
| Chromophobe renal cell carcinoma with prolonged response to sequential sunitinib and everolimus. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110320 |
| Translational medicine: Cancer lessons from mice to humans. | Nature 20110317 |
| The impact of tumor burden characteristics in patients with metastatic renal cell carcinoma treated with sunitinib. | Cancer 20110315 |
| Fibroblast growth factor 2 regulates endothelial cell sensitivity to sunitinib. | Oncogene 20110310 |
| Pancreatic neuroendocrine tumors: role of novel agents. Highlights from the '2011 ASCO Gastrointestinal Cancers Symposium'. San Francisco, CA, USA. January 20-22, 2011. | JOP : Journal of the pancreas 20110309 |
| Osteonecrosis of the jaw related to sunitinib. | Oral and maxillofacial surgery 20110301 |
| Marginal increase of sunitinib exposure by grapefruit juice. | Cancer chemotherapy and pharmacology 20110301 |
| [Multimodal interventional therapy of a large renal cell carcinoma in a patient with high anesthesia risk - a case report]. | RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 20110301 |
| Sunitinib and other targeted therapies for renal cell carcinoma. | British journal of cancer 20110301 |
| PET of αvbeta3-integrin and αvbeta5-integrin expression with 18F-fluciclatide for assessment of response to targeted therapy: ready for prime time? | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110301 |
| Monitoring tumor response to antiangiogenic sunitinib therapy with 18F-fluciclatide, an 18F-labeled αVbeta3-integrin and αV beta5-integrin imaging agent. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110301 |
| Spontaneous regression of metastatic renal cancer after short-term treatment with sunitinib. | International journal of urology : official journal of the Japanese Urological Association 20110301 |
| A CT scan aspect of 'hypodense thyroid gland' after sunitinib treatment for metastatic carcinoma of the kidney. | The Journal of clinical endocrinology and metabolism 20110301 |
| [Clinical case of the month. A patient with advanced non-small-cell lung cancer presenting with an exceptional response to targeted therapies]. | Revue medicale de Liege 20110301 |
| [Current status in molecular-targeted therapy and IFNα for renal cell carcinoma in Japan]. | Hinyokika kiyo. Acta urologica Japonica 20110301 |
| Exploratory analysis of early toxicity of sunitinib in advanced hepatocellular carcinoma patients: kinetics and potential biomarker value. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110215 |
| Phase 1 dose-escalation trial of tremelimumab plus sunitinib in patients with metastatic renal cell carcinoma. | Cancer 20110215 |
| Current and emerging pharmacological treatments for gastrointestinal stromal tumour. | Drugs 20110212 |
| Sunitinib malate for the treatment of pancreatic neuroendocrine tumors. | The New England journal of medicine 20110210 |
| Promising advances in the treatment of malignant pancreatic endocrine tumors. | The New England journal of medicine 20110210 |
| Osteonecrosis of the jaw and the role of macrophages. | Journal of the National Cancer Institute 20110202 |
| Perfusion patterns of metastatic gastrointestinal stromal tumor lesions under specific molecular therapy. | European journal of radiology 20110201 |
| Prognostic factors for progression-free and overall survival with sunitinib targeted therapy and with cytokine as first-line therapy in patients with metastatic renal cell carcinoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20110201 |
| A phase II study of sunitinib in patients with recurrent epithelial ovarian and primary peritoneal carcinoma: an NCIC Clinical Trials Group Study. | Annals of oncology : official journal of the European Society for Medical Oncology 20110201 |
| Hypothyroidism in patients with renal cell carcinoma: blessing or curse? | Cancer 20110201 |
| Sunitinib in metastatic renal cell carcinoma patients with brain metastases. | Cancer 20110201 |
| Genetic polymorphisms associated with a prolonged progression-free survival in patients with metastatic renal cell cancer treated with sunitinib. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110201 |
| Nasal metastases from renal cell carcinoma are associated with Memorial Sloan-Kettering Cancer Center poor-prognosis classification. | Chinese journal of cancer 20110201 |
| [Management of hypothyroidism secondary to tyrosine kinase inhibitors: description of treatment in three distinct clinical settings]. | Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20110201 |
| The oral tyrosine kinase inhibitors lapatinib and sunitinib: new opportunities for the treatment of brain metastases from breast cancer? | Expert review of anticancer therapy 20110201 |
| Targeted therapies for the treatment of metastatic renal cell carcinoma: clinical evidence. | The oncologist 20110201 |
| Beyond traditional outcomes: improving quality of life in patients with renal cell carcinoma. | The oncologist 20110201 |
| Treatment-associated adverse event management in the advanced renal cell carcinoma patient treated with targeted therapies. | The oncologist 20110201 |
| The incidence and mechanism of sunitinib-induced thyroid atrophy in patients with metastatic renal cell carcinoma. | British journal of cancer 20110118 |
| Evolution of renal function in patients treated with antiangiogenics after nephrectomy for renal cell carcinoma. | Urologic oncology 20110101 |
| An adult Xp11.2 translocation renal carcinoma showing response to treatment with sunitinib. | Urologic oncology 20110101 |
| Targeting immune suppressing myeloid-derived suppressor cells in oncology. | Critical reviews in oncology/hematology 20110101 |
| Effect of tyrosine kinase inhibitor treatment of renal cell carcinoma on the accumulation of carbonic anhydrase IX-specific chimeric monoclonal antibody cG250. | BJU international 20110101 |
| Predictors of response to sequential sunitinib and the impact of prior VEGF-targeted drug washout in patients with metastatic clear-cell renal cell carcinoma. | Urologic oncology 20110101 |
| Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells. | Journal of neuro-oncology 20110101 |
| Clinical efficacy and safety of sunitinib after imatinib failure in Japanese patients with gastrointestinal stromal tumor. | Japanese journal of clinical oncology 20110101 |
| Molecular basis of hypertension side effects induced by sunitinib. | Anti-cancer drugs 20110101 |
| The effect of sunitinib on immune subsets in metastatic clear cell renal cancer. | Urologia internationalis 20110101 |
| Nephrotoxicities associated with the use of tyrosine kinase inhibitors: a single-center experience and review of the literature. | Nephron. Clinical practice 20110101 |
| The impact of cytoreductive nephrectomy on survival of patients with metastatic renal cell carcinoma receiving vascular endothelial growth factor targeted therapy. | The Journal of urology 20110101 |
| VEGF-PET imaging is a noninvasive biomarker showing differential changes in the tumor during sunitinib treatment. | Cancer research 20110101 |
| PDGFR signaling blockade in marrow stroma impairs lung cancer bone metastasis. | Cancer research 20110101 |
| Kidney cancer: Does hypothyroidism predict clinical outcome? | Nature reviews. Urology 20110101 |
| Metastatic gastrointestinal stromal tumors. | Cancer chemotherapy and pharmacology 20110101 |
| Management of a new isolated metastasis during sunitinib treatment in renal cell carcinoma patients: a lesson from two cases. | Urologia internationalis 20110101 |
| Role of tyrosine kinase inhibitors in tumor immunology. | Immunotherapy 20110101 |
| A phase I study of recombinant human interleukin-21 (rIL-21) in combination with sunitinib in patients with metastatic renal cell carcinoma (RCC). | Acta oncologica (Stockholm, Sweden) 20110101 |
| Biomarker response on exposure to sunitinib and its primary metabolite (SU12662) in metastatic colorectal cancer patients. | International journal of clinical pharmacology and therapeutics 20110101 |
| A preliminary report of a Phase II study of folinic acid, 5-fluorouracil, irinotecan (FOLFIRI) plus sunitinib with toxicity, efficacy, pharmacokinetics, biomarker, imaging data in patients with colorectal cancer with liver metastases as 1st line treatment. | International journal of clinical pharmacology and therapeutics 20110101 |
| Mechanisms of resistance to imatinib and sunitinib in gastrointestinal stromal tumor. | Cancer chemotherapy and pharmacology 20110101 |
| Effect of sunitinib combined with ionizing radiation on endothelial cells. | Journal of radiation research 20110101 |
| In pursuit of new anti-angiogenic therapies for cancer treatment. | Frontiers in bioscience (Landmark edition) 20110101 |
| Therapeutic advances in women's cancers. | Frontiers in bioscience (Scholar edition) 20110101 |
| A novel angiogenesis inhibitor, sunitinib malate, in encapsulating peritoneal sclerosis. | Journal of nephrology 20110101 |
| Tumor fistulization associated with targeted therapy: computed tomographic findings and clinical consequences. | Journal of computer assisted tomography 20110101 |
| Pleiotropic stromal effects of vascular endothelial growth factor receptor 2 antibody therapy in renal cell carcinoma models. | Neoplasia (New York, N.Y.) 20110101 |
| [AUO (Working Group on Urological Oncology) study of metastasized renal cell carcinoma: prospective randomized multicenter phase II study on resection of pulmonary metastases in clear cell renal cell carcinoma with or without adjuvant sunitinib therapy over 1 year (SMAT - AN 20/04 AUO)]. | Der Urologe. Ausg. A 20110101 |
| [Experience with sunitinib in hormone-resistant metastatic prostate cancer that is unresponsive to docetaxel]. | Actas urologicas espanolas 20110101 |
| [Comment to: 'Experience with sunitinib in hormone-resistant metastatic prostate cancer that is unresponsive to docetaxel']. | Actas urologicas espanolas 20110101 |
| A 51-year-old man with rapidly progressive metastatic sarcomatoid renal cell carcinoma: an apparent complete clinical response to second-line therapy with sunitinib and low-dose interferon-alpha. | Clinical advances in hematology & oncology : H&O 20110101 |
| Psychotic symptoms in the course of sunitinib treatment for advanced renal cell cancer. Two cases. | General hospital psychiatry 20110101 |
| Multidrug resistance protein 2 implicates anticancer drug-resistance to sorafenib. | Biological & pharmaceutical bulletin 20110101 |
| Safety and treatment patterns of multikinase inhibitors in patients with metastatic renal cell carcinoma at a tertiary oncology center in Italy. | BMC cancer 20110101 |
| Management of tyrosine kinase inhibitor-induced hand-foot skin reaction: viewpoints from the medical oncologist, dermatologist, and oncology nurse. | The journal of supportive oncology 20110101 |
| [Tumor lysis syndrome in a patient with a renal carcinoma treated with sunitinib]. | Medicina 20110101 |
| Early experience with targeted therapy and dendritic cell vaccine in metastatic renal cell carcinoma after nephrectomy. | International braz j urol : official journal of the Brazilian Society of Urology 20110101 |
| Development of an AlphaScreen-based high-throughput screening assay for inhibitors of human vascular endothelial growth factor receptor-3. | Journal of immunoassay & immunochemistry 20110101 |
| [Use of sunitinib in metastatic renal cell carcinoma patients with poor prognosis]. | Voprosy onkologii 20110101 |
| Efficacy of temsirolimus after previous treatment with sunitinib, sorafenib or everolimus in advanced renal cell cancer. | Oncology 20110101 |
| Efficacy of sunitinib rechallenge in kidney cancer: are mTOR inhibitors involved or is it only a matter of time? | Onkologie 20110101 |
| Efficacy of sunitinib re-exposure after failure of an mTOR inhibitor in patients with metastatic RCC. | Onkologie 20110101 |
| Bevacizumab plus interferon-α versus sunitinib for first-line treatment of renal cell carcinoma in Italy: a cost-minimization analysis. | Clinical drug investigation 20110101 |
| [Gastrointestinal stromal tumors]. | Annali italiani di chirurgia 20110101 |
| Angiogenesis in peritoneal dialysis. | Kidney & blood pressure research 20110101 |
| Sunitinib inhibits lymphatic endothelial cell functions and lymph node metastasis in a breast cancer model through inhibition of vascular endothelial growth factor receptor 3. | Breast cancer research : BCR 20110101 |
| New perspectives: role of Sunitinib in breast cancer. | La Clinica terapeutica 20110101 |
| Evidence of distinct tumour-propagating cell populations with different properties in primary human hepatocellular carcinoma. | PloS one 20110101 |
| How to manage hypersensitivity reactions to biological agents? | European journal of dermatology : EJD 20110101 |
| Metastatic collecting duct carcinoma of the kidney treated with sunitinib. | World journal of surgical oncology 20110101 |
| Identification of novel therapeutic targets in microdissected clear cell ovarian cancers. | PloS one 20110101 |
| Intrinsic resistance to tyrosine kinase inhibitors is associated with poor clinical outcome in metastatic renal cell carcinoma. | BMC cancer 20110101 |
| Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib. | Journal of translational medicine 20110101 |
| Targeted drug therapies and cancer. | Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20110101 |
| Sunitinib for Asian patients with advanced renal cell carcinoma: a comparable efficacy with different toxicity profiles. | Oncology 20110101 |
| Nilotinib is effective in imatinib and sunitinib resistant GIST: a case report. | Hepato-gastroenterology 20110101 |
| [Evaluation of information about prophylactic treatment and management of hand-foot reactions caused by antiangiogenic therapies]. | Annales de dermatologie et de venereologie 20110101 |
| Cutaneous toxicities of the multikinase inhibitors sorafenib and sunitinib. | Dermatologic therapy 20110101 |
| The expression and role of protein kinase C (PKC) epsilon in clear cell renal cell carcinoma. | Journal of experimental & clinical cancer research : CR 20110101 |
| Improved curve fits to summary survival data: application to economic evaluation of health technologies. | BMC medical research methodology 20110101 |
| Nilotinib in advanced gastrointestinal stromal tumors after imatinib and sunitinib therapy. | Hepato-gastroenterology 20110101 |
| Sunitinib induced pyoderma gangrenosum-like ulcerations. | European journal of medical research 20110101 |
| Functional MRI techniques demonstrate early vascular changes in renal cell cancer patients treated with sunitinib: a pilot study. | Cancer imaging : the official publication of the International Cancer Imaging Society 20110101 |
| Successful treatment with sunitinib in a young patient with metastatic gastrointestinal stromal tumor after failure on adjuvant imatinib. | Journal of cancer research and therapeutics 20110101 |
| Successful treatment of T4 renal cell carcinoma after a neoadjuvant targeted therapy using sunitinib: report of a case. | The Kurume medical journal 20110101 |
| HGF/c-Met acts as an alternative angiogenic pathway in sunitinib-resistant tumors. | Cancer research 20101215 |
| Dual functional monoclonal antibody PF-04605412 targets integrin alpha5beta1 and elicits potent antibody-dependent cellular cytotoxicity. | Cancer research 20101215 |
| Recurrent scrotal hemangiomas during treatment with sunitinib. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101210 |
| Phase I/II study of sunitinib malate in Japanese patients with gastrointestinal stromal tumor after failure of prior treatment with imatinib mesylate. | Investigational new drugs 20101201 |
| Phase I/II trial of sunitinib plus gefitinib in patients with metastatic renal cell carcinoma. | American journal of clinical oncology 20101201 |
| SABRE-B: an evaluation of paclitaxel and bevacizumab with or without sunitinib as first-line treatment of metastatic breast cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20101201 |
| Metastatic renal cell carcinoma complicated with diffuse alveolar hemorrhage: a rare adverse effect of sunitinib. | International journal of clinical oncology 20101201 |
| Presurgical targeted therapy with tyrosine kinase inhibitors for advanced renal cell carcinoma: clinical results and histopathological therapeutic effects. | Japanese journal of clinical oncology 20101201 |
| [Thyroid dysfunction in patients with advanced renal cell carcinoma treated with sunitinib: a multifactorial issue]. | Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20101201 |
| Overall survival and updated results from a phase II study of sunitinib in Japanese patients with metastatic renal cell carcinoma. | Japanese journal of clinical oncology 20101201 |
| Sorafenib in patients with metastatic renal cell carcinoma refractory to either sunitinib or bevacizumab. | Cancer 20101201 |
| Third-line sorafenib after sequential therapy with sunitinib and mTOR inhibitors in metastatic renal cell carcinoma. | European urology 20101201 |
| Fatal necrotizing pancreatitis during combined treatment with erlotinib and sunitinib. | Lung cancer (Amsterdam, Netherlands) 20101201 |
| The immunocytokine F8-IL2 improves the therapeutic performance of sunitinib in a mouse model of renal cell carcinoma. | The Journal of urology 20101201 |
| Phase II trials of single-agent anti-VEGF therapy for patients with chronic lymphocytic leukemia. | Leukemia & lymphoma 20101201 |
| Sunitinib rechallenge in metastatic renal cell carcinoma patients. | Cancer 20101201 |
| Targeting STAT3 in adoptively transferred T cells promotes their in vivo expansion and antitumor effects. | Cancer research 20101201 |
| A Cancer and Leukemia Group B phase II study of sunitinib malate in patients with previously treated metastatic pancreatic adenocarcinoma (CALGB 80603). | The oncologist 20101201 |
| [Recent advancements in the treatment of renal cell carcinoma--focus on international guidelines]. | Magyar onkologia 20101201 |
| The effects of anti-VEGFR and anti-EGFR agents on glioma cell migration through implication of growth factors with integrins. | Anticancer research 20101201 |
| Efficacy of sunitinib in patients with renal cell carcinoma with bone metastases. | Anticancer research 20101201 |
| Response and safety of sunitinib in a heavily pre-treated metastatic non-small cell lung carcinoma patient. | Anticancer research 20101201 |
| More than 4 years of progression-free survival in a patient with metastatic renal cell carcinoma treated sequentially with sunitinib, everolimus, sorafenib, and temsirolimus. | Anticancer research 20101201 |
| Novel potent orally active multitargeted receptor tyrosine kinase inhibitors: synthesis, structure-activity relationships, and antitumor activities of 2-indolinone derivatives. | Journal of medicinal chemistry 20101125 |
| Activation state-dependent binding of small molecule kinase inhibitors: structural insights from biochemistry. | Chemistry & biology 20101124 |
| Vascular endothelial growth factor-targeted therapy for the treatment of adult metastatic Xp11.2 translocation renal cell carcinoma. | Cancer 20101115 |
| The cancer-HIV/AIDS treatment conundrum. | Journal of the National Cancer Institute 20101103 |
| Sunitinib in combination with gemcitabine plus cisplatin for advanced non-small cell lung cancer: a phase I dose-escalation study. | Lung cancer (Amsterdam, Netherlands) 20101101 |
| Association of percentage of tumour burden removed with debulking nephrectomy and progression-free survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted therapy. | BJU international 20101101 |
| Feasibility and efficacy of neoadjuvant sunitinib before nephron-sparing surgery. | BJU international 20101101 |
| Angiogenesis as a therapeutic target in urothelial carcinoma. | Anti-cancer drugs 20101101 |
| Changes in resting energy expenditure (REE) as a function of tumor response to sunitinib in a cachexic patient with a metastatic endocrine tumor of the pancreas. | Acta oncologica (Stockholm, Sweden) 20101101 |
| Phase II study of daily sunitinib in FDG-PET-positive, iodine-refractory differentiated thyroid cancer and metastatic medullary carcinoma of the thyroid with functional imaging correlation. | Clinical cancer research : an official journal of the American Association for Cancer Research 20101101 |
| Pharmacophore modeling and virtual screening studies for new VEGFR-2 kinase inhibitors. | European journal of medicinal chemistry 20101101 |
| A novel primary KIT exon 9 single nucleotide substitution c.1427G>T (p.Ser476Ile) in a gastrointestinal stromal tumor. | Virchows Archiv : an international journal of pathology 20101101 |
| Progression of intramedullary metastasis during perioperative cessation of sunitinib. | Nature reviews. Urology 20101101 |
| [Multimodality therapy concepts for soft tissue sarcomas]. | Der Internist 20101101 |
| Bevacizumab for metastatic renal cell carcinoma: a monoclonal antibody in a sea of small molecules. | Expert opinion on biological therapy 20101101 |
| ¹¹C-methionine positron-emission tomography and computed tomography (PET-CT) in evaluating metastatic transitional cell carcinoma response to sunitinib therapy. | BJU international 20101101 |
| Biological targeted therapies in patients with advanced enteropancreatic neuroendocrine carcinomas. | Cancer treatment reviews 20101101 |
| mTOR inhibition by everolimus counteracts VEGF induction by sunitinib and improves anti-tumor activity against gastric cancer in vivo. | Cancer letters 20101028 |
| [New possibilities of targeted therapy in the treatment of hepatocellular carcinoma with the help of molecular biology]. | Orvosi hetilap 20101024 |
| Risk of arterial thrombosis not increased by sorafenib or sunitinib. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101020 |
| Novel azulene-based derivatives as potent multi-receptor tyrosine kinase inhibitors. | Bioorganic & medicinal chemistry letters 20101015 |
| Comment on 'costs of managing adverse events in the treatment of first-line metastatic renal cell carcinoma: bevacizumab in combination with interferon-α2a compared with sunitinib'. | British journal of cancer 20101012 |
| A phase I study of sunitinib plus capecitabine in patients with advanced solid tumors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101010 |
| Sunitinib inducing tumor lysis syndrome in a patient treated for renal carcinoma. | Investigational new drugs 20101001 |
| An in vitro study, evaluating the effect of sunitinib and/or lapatinib on two glioma cell lines. | Investigational new drugs 20101001 |
| Phase II study of sunitinib malate in head and neck squamous cell carcinoma. | Investigational new drugs 20101001 |
| Gastrointestinal stromal tumors: current management. | Journal of surgical oncology 20101001 |
| The potential role of sunitinib in gastrointestinal cancers other than GIST. | Critical reviews in oncology/hematology 20101001 |
| The efficacy and safety of sunitinib in korean patients with advanced renal cell carcinoma: high incidence of toxicity leads to frequent dose reduction. | Japanese journal of clinical oncology 20101001 |
| Optimizing the use of sunitinib in metastatic renal cell carcinoma: an update from clinical practice. | Cancer investigation 20101001 |
| Inhibition of corneal neovascularization by topical bevacizumab (Anti-VEGF) and Sunitinib (Anti-VEGF and Anti-PDGF) in an animal model. | American journal of ophthalmology 20101001 |
| Autophagy plays an important role in sunitinib-mediated cell death in H9c2 cardiac muscle cells. | Toxicology and applied pharmacology 20101001 |
| Prediction of response to preoperative chemoradiotherapy in rectal cancer by multiplex kinase activity profiling. | International journal of radiation oncology, biology, physics 20101001 |
| Metastatic mucinous tubular and spindle cell carcinoma of the kidney responding to sunitinib. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101001 |
| SU11248, a selective tyrosine kinases inhibitor suppresses breast tumor angiogenesis and growth via targeting both tumor vasculature and breast cancer cells. | Cancer biology & therapy 20101001 |
| Implications of mutational analysis for the management of patients with gastrointestinal stromal tumors and the application of targeted therapies. | Cancer investigation 20101001 |
| Sunitinib may raise the risk of bisphosphonate-related osteonecrosis of the jaw: presentation of three cases. | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20101001 |
| Evidence-based urology in practice: randomized controlled trials stopped early for benefit. | BJU international 20101001 |
| Deciphering the anticancer mechanisms of sunitinib. | Cancer biology & therapy 20101001 |
| Recall pneumonitis during systemic treatment with sunitinib. | Annals of oncology : official journal of the European Society for Medical Oncology 20101001 |
| Renal cell carcinoma and acute promyelocytic leukemia: a nonrandom association? | American journal of hematology 20101001 |
| Receptor tyrosine kinase inhibition, hypertension, and proteinuria: is endothelin the smoking gun? | Hypertension (Dallas, Tex. : 1979) 20101001 |
| Hypertension induced by the tyrosine kinase inhibitor sunitinib is associated with increased circulating endothelin-1 levels. | Hypertension (Dallas, Tex. : 1979) 20101001 |
| [Leg ulcerations and sunitinib]. | Annales de dermatologie et de venereologie 20101001 |
| [Molecular targeted therapy for renal cell carcinoma and other urological cancers]. | Nihon rinsho. Japanese journal of clinical medicine 20101001 |
| Novel multitargeted anticancer oral therapies: sunitinib and sorafenib as a paradigm. | The Israel Medical Association journal : IMAJ 20101001 |
| [Clinical manifestation of targeted drugs in individualized therapy of malignant tumors]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20101001 |
| A phase I, dose-finding study of sunitinib in combination with irinotecan in patients with advanced solid tumours. | British journal of cancer 20100928 |
| Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser(910)/Ser(935), disruption of 14-3-3 binding and altered cytoplasmic localization. | The Biochemical journal 20100915 |
| Safety and efficacy of the combination of erlotinib and sirolimus for the treatment of metastatic renal cell carcinoma after failure of sunitinib or sorafenib. | British journal of cancer 20100907 |
| Imatinib mesylate-induced acute liver failure in a patient with gastrointestinal stromal tumors. | Medical oncology (Northwood, London, England) 20100901 |
| Spontaneous pyopneumothorax in patients treated with mTOR inhibitors for subpleural pulmonary metastases. | Medical oncology (Northwood, London, England) 20100901 |
| Recovery of paraneoplastic hypercalcemia by sunitinib treatment for renal cell carcinoma: a case report and review of the literature. | Medical oncology (Northwood, London, England) 20100901 |
| Analysis of anti-proliferative and chemosensitizing effects of sunitinib on human esophagogastric cancer cells: Synergistic interaction with vandetanib via inhibition of multi-receptor tyrosine kinase pathways. | International journal of cancer 20100901 |
| Sunitinib in combination with docetaxel in patients with advanced solid tumors: a phase I dose-escalation study. | Cancer chemotherapy and pharmacology 20100901 |
| Pharmacokinetics of sunitinib malate in subjects with hepatic impairment. | Cancer chemotherapy and pharmacology 20100901 |
| Angiogenic blockade and radiotherapy in hepatocellular carcinoma. | International journal of radiation oncology, biology, physics 20100901 |
| Targeted agents in metastatic Xp11 translocation/TFE3 gene fusion renal cell carcinoma (RCC): a report from the Juvenile RCC Network. | Annals of oncology : official journal of the European Society for Medical Oncology 20100901 |
| Carbonic anhydrase IX and pathological features as predictors of outcome in patients with metastatic clear-cell renal cell carcinoma receiving vascular endothelial growth factor-targeted therapy. | BJU international 20100901 |
| Downsizing treatment with tyrosine kinase inhibitors in patients with advanced gastrointestinal stromal tumors improved resectability. | World journal of surgery 20100901 |
| Sunitinib-induced pseudoprogression after whole-brain radiotherapy for metastatic renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100901 |
| Sunitinib-induced reduction in skin microvascular density is a reversible phenomenon. | Annals of oncology : official journal of the European Society for Medical Oncology 20100901 |
| Sunitinib inhibits MEK/ERK and SAPK/JNK pathways and increases sodium/iodide symporter expression in papillary thyroid cancer. | Thyroid : official journal of the American Thyroid Association 20100901 |
| Prospective clinical trial of preoperative sunitinib in patients with renal cell carcinoma. | The Journal of urology 20100901 |
| Multicenter phase II randomized trial evaluating antiangiogenic therapy with sunitinib as consolidation after objective response to taxane chemotherapy in women with HER2-negative metastatic breast cancer. | Breast cancer research and treatment 20100901 |
| Severe rhabdomyolysis during sunitinib treatment of metastatic renal cell carcinoma. A report of two cases. | Annals of oncology : official journal of the European Society for Medical Oncology 20100901 |
| Sunitinib-induced thyrotoxicosis followed by persistent hypothyroidism with shrinkage of thyroid volume. | The Tohoku journal of experimental medicine 20100901 |
| Sunitinib for metastatic renal cell carcinoma. | Future oncology (London, England) 20100901 |
| [A case of recurrent intracaval renal cell carcinoma effectively treated with sunitinib]. | Hinyokika kiyo. Acta urologica Japonica 20100901 |
| Sunitinib (SU11248) inhibits growth of human ovarian cancer in xenografted mice. | Anticancer research 20100901 |
| Myelosuppression by sunitinib is flt-3 genotype dependent. | British journal of cancer 20100824 |
| Anti-inflammatory M2 type macrophages characterize metastasized and tyrosine kinase inhibitor-treated gastrointestinal stromal tumors. | International journal of cancer 20100815 |
| Neoadjuvant treatment of unresectable medullary thyroid cancer with sunitinib. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100810 |
| Phase II trial of sunitinib in patients with relapsed or refractory germ cell tumors. | Investigational new drugs 20100801 |
| Sunitinib and sorafenib in metastatic renal cell carcinoma patients with renal insufficiency. | Annals of oncology : official journal of the European Society for Medical Oncology 20100801 |
| MGMT modulates glioblastoma angiogenesis and response to the tyrosine kinase inhibitor sunitinib. | Neuro-oncology 20100801 |
| Current and predicted cost of metastatic renal cell carcinoma in Finland. | Acta oncologica (Stockholm, Sweden) 20100801 |
| Identification of a secondary FLT3/A848P mutation in a patient with FLT3-ITD-positive blast phase CMML and response to sunitinib and sorafenib. | Leukemia 20100801 |
| Crystal structures of IL-2-inducible T cell kinase complexed with inhibitors: insights into rational drug design and activity regulation. | Chemical biology & drug design 20100801 |
| Metastatic renal carcinoma: evaluation of antiangiogenic therapy with dynamic contrast-enhanced CT. | Radiology 20100801 |
| The application of the National Institute of Clinical Excellence guidelines for treatment of metastatic renal cell carcinoma in the United Kingdom: friend or foe? | BJU international 20100801 |
| Sunitinib in patients with metastatic renal cell carcinoma: Birmingham experience. | Oncology reports 20100801 |
| Addition of sunitinib to cetuximab and irinotecan in patients with heavily pre-treated advanced colorectal cancer. | Acta oncologica (Stockholm, Sweden) 20100801 |
| Differences in effects on myocardium and mitochondria by angiogenic inhibitors suggest separate mechanisms of cardiotoxicity. | Toxicologic pathology 20100801 |
| [Cutaneous side effects of the multikinase inhibitors sorafenib and sunitinib]. | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20100801 |
| Benefits from pharmacological and pharmacokinetic properties of sunitinib for clinical development. | Expert opinion on drug metabolism & toxicology 20100801 |
| Impact of the incorporation of tyrosine kinase inhibitor agents on the treatment of patients with a diagnosis of advanced renal cell carcinoma: study based on experience at the Hospital Universitario Central de Asturias. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20100801 |
| Phase II study of sunitinib in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis. | Clinical lymphoma, myeloma & leukemia 20100801 |
| A cost-effectiveness analysis of sunitinib in patients with metastatic renal cell carcinoma intolerant to or experiencing disease progression on immunotherapy: perspective of the Spanish National Health System. | Journal of clinical pharmacy and therapeutics 20100801 |
| Synergistic antitumor effect of TRAIL in combination with sunitinib in vitro and in vivo. | Cancer letters 20100728 |
| Sunitinib deregulates tumor adaptation to hypoxia by inhibiting HIF-1alpha synthesis in HT-29 colon cancer cells. | Biochemical and biophysical research communications 20100723 |
| Design, synthesis and evaluation of 2-amino-4-m-bromoanilino-6-arylmethyl-7H-pyrrolo[2,3-d]pyrimidines as tyrosine kinase inhibitors and antiangiogenic agents. | Bioorganic & medicinal chemistry 20100715 |
| Sunitinib in metastatic thymic carcinomas: laboratory findings and initial clinical experience. | British journal of cancer 20100713 |
| Comparison of conventional time-intensity curves vs. maximum intensity over time for post-processing of dynamic contrast-enhanced ultrasound. | European journal of radiology 20100701 |
| Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: results of a pharmacokinetic/pharmacodynamic meta-analysis. | Cancer chemotherapy and pharmacology 20100701 |
| An exploratory study of sunitinib plus paclitaxel as first-line treatment for patients with advanced breast cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20100701 |
| Spontaneous bilateral pneumothorax in metastatic renal cell carcinoma on sunitinib therapy. | Cancer chemotherapy and pharmacology 20100701 |
| New drugs in neuroendocrine tumors: rising of new therapeutic philosophies? | Current opinion in oncology 20100701 |
| SU11248 (sunitinib) directly inhibits the activity of mammalian 5'-AMP-activated protein kinase (AMPK). | Cancer biology & therapy 20100701 |
| Cardiovascular safety of VEGF-targeting therapies: current evidence and handling strategies. | The oncologist 20100701 |
| Synthesis and structure-activity relationship of 6-arylureido-3-pyrrol-2-ylmethylideneindolin-2-one derivatives as potent receptor tyrosine kinase inhibitors. | Bioorganic & medicinal chemistry 20100701 |
| Close encounters of a novel kind: a multi-targeted cancer drug meets a metabolic sensor. | Cancer biology & therapy 20100701 |
| Metronomic gemcitabine in combination with sunitinib inhibits multisite metastasis and increases survival in an orthotopic model of pancreatic cancer. | Molecular cancer therapeutics 20100701 |
| Tyrosine kinase inhibitors in treating soft tissue sarcomas: sunitinib in non-GIST sarcomas. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20100701 |
| [Efficacy of tyrosine kinase inhibitor therapy combined with surgical resection in patients with metastatic gastrointestinal stromal tumor]. | Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20100701 |
| [The role of pathologists in the target therapy of gastrointestinal tumors]. | Zhonghua bing li xue za zhi = Chinese journal of pathology 20100701 |
| Drug-induced vessel remodeling in bone metastases as assessed by dynamic contrast enhanced magnetic resonance imaging and vessel size imaging: a longitudinal in vivo study. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100615 |
| Molecular basis and management of gastrointestinal stromal tumors. | World journal of gastroenterology 20100614 |
| Toxicity of sunitinib plus bevacizumab in renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100610 |
| Decreased exposure to sunitinib due to concomitant administration of ifosfamide: results of a phase I and pharmacokinetic study on the combination of sunitinib and ifosfamide in patients with advanced solid malignancies. | British journal of cancer 20100608 |
| Feasibility of sequential use of sunitinib and temsirolimus in advanced renal cell carcinoma. | Medical oncology (Northwood, London, England) 20100601 |
| Olecranon bursitis in patients treated with sunitinib for renal cell carcinoma. | Medical oncology (Northwood, London, England) 20100601 |
| Frequent dose interruptions are required for patients receiving oral kinase inhibitor therapy for advanced renal cell carcinoma. | American journal of clinical oncology 20100601 |
| Update on systemic therapies of metastatic renal cell carcinoma. | World journal of urology 20100601 |
| Pharmacological interaction with sunitinib is abolished by a germ-line mutation (1291T>C) of BCRP/ABCG2 gene. | Cancer science 20100601 |
| ABCG2 421C>A polymorphism and high exposure of sunitinib in a patient with renal cell carcinoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20100601 |
| Treatment with tyrosine kinase inhibitors for patients with differentiated thyroid cancer: the M. D. Anderson experience. | The Journal of clinical endocrinology and metabolism 20100601 |
| Improvement of psoriasis during sunitinib therapy for renal cell carcinoma. | The American journal of the medical sciences 20100601 |
| Management of sunitinib-related adverse events: an evidence- and expert-based consensus approach. | World journal of urology 20100601 |
| [Antiangionic drugs in soft tissue sarcoma]. | Bulletin du cancer 20100601 |
| [Focus on GIST management]. | Bulletin du cancer 20100601 |
| Molecular imaging of changes in the prevalence of vascular endothelial growth factor receptor in sunitinib-treated murine mammary tumors. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100601 |
| Morphology, Attenuation, Size, and Structure (MASS) criteria: assessing response and predicting clinical outcome in metastatic renal cell carcinoma on antiangiogenic targeted therapy. | AJR. American journal of roentgenology 20100601 |
| Reversible epithelial to mesenchymal transition and acquired resistance to sunitinib in patients with renal cell carcinoma: evidence from a xenograft study. | Molecular cancer therapeutics 20100601 |
| Harvesting the low-hanging fruit: kinase inhibitors for therapy of advanced medullary and nonmedullary thyroid cancer. | The Journal of clinical endocrinology and metabolism 20100601 |
| [Treatment with antiangiogenic drugs]. | Nihon rinsho. Japanese journal of clinical medicine 20100601 |
| [Anti-angiogenic drugs]. | Nihon rinsho. Japanese journal of clinical medicine 20100601 |
| Hematologic toxicity in patients treated with sunitinib for advanced thyroid cancer. | Thyroid : official journal of the American Thyroid Association 20100601 |
| Renal cell carcinoma: ten years of significant advances. | Targeted oncology 20100601 |
| Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors. | Oncogene 20100520 |
| Pharmacologic modulation of niche accessibility via tyrosine kinase inhibition enhances marrow and thymic engraftment after hematopoietic stem cell transplantation. | Blood 20100520 |
| Synthesis and biological activity of N(4)-phenylsubstituted-6-(2,4-dichloro phenylmethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines as vascular endothelial growth factor receptor-2 inhibitors and antiangiogenic and antitumor agents. | Bioorganic & medicinal chemistry 20100515 |
| Tyrosine kinase inhibitors and acute pancreatitis. | JOP : Journal of the pancreas 20100505 |
| Optimizing the size variation threshold for the CT evaluation of response in metastatic renal cell carcinoma treated with sunitinib. | Annals of oncology : official journal of the European Society for Medical Oncology 20100501 |
| The loss of radiographic enhancement in primary renal cell carcinoma tumors following multitargeted receptor tyrosine kinase therapy is an additional indicator of response. | Urology 20100501 |
| Tumor response to sunitinib malate observed in clear-cell sarcoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20100501 |
| Progression of a caval vein thrombus in two patients with primary renal cell carcinoma on pretreatment with sunitinib. | Acta oncologica (Stockholm, Sweden) 20100501 |
| Predictive value of baseline serum vascular endothelial growth factor and neutrophil gelatinase-associated lipocalin in advanced kidney cancer patients receiving sunitinib. | Kidney international 20100501 |
| Phase III randomized trial of sunitinib versus capecitabine in patients with previously treated HER2-negative advanced breast cancer. | Breast cancer research and treatment 20100501 |
| Inhibition of gamma-secretase by the CK1 inhibitor IC261 does not depend on CK1delta. | Bioorganic & medicinal chemistry letters 20100501 |
| Risk of arterial thromboembolic events with sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100501 |
| Pharmacokinetic/pharmacodynamic modeling of biomarker response to sunitinib in healthy volunteers. | Clinical pharmacology and therapeutics 20100501 |
| The promise of biomarkers for personalized renal cancer care. | Kidney international 20100501 |
| Direct and differential suppression of myeloid-derived suppressor cell subsets by sunitinib is compartmentally constrained. | Cancer research 20100501 |
| Editorial comment. | Urology 20100501 |
| Editorial comment. | Urology 20100501 |
| Sunitinib malate and figitumumab in solitary fibrous tumor: patterns and molecular bases of tumor response. | Molecular cancer therapeutics 20100501 |
| [Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma]. | Aktuelle Urologie 20100501 |
| Necrosis of a skin autograft after short-term treatment with sunitinib in a 14-year-old girl with metastatic alveolar soft part sarcoma of the thigh. | Klinische Padiatrie 20100501 |
| Current management of GISTs. | Clinical advances in hematology & oncology : H&O 20100501 |
| Present state of target therapy for disseminated renal cell carcinoma. | Immunotherapy 20100501 |
| The cardiotoxicity and myocyte damage caused by small molecule anticancer tyrosine kinase inhibitors is correlated with lack of target specificity. | Toxicology and applied pharmacology 20100415 |
| Ongoing under-reporting of clinically relevant safety data in phase II studies of tyrosine kinase inhibitors. | British journal of cancer 20100413 |
| Hemangiopericytoma and antiangiogenic therapy: clinical benefit of antiangiogenic therapy (sorafenib and sunitinib) in relapsed malignant haemangioperyctoma /solitary fibrous tumour. | Investigational new drugs 20100401 |
| Pharmacokinetics and safety of sunitinib malate in subjects with impaired renal function. | Journal of clinical pharmacology 20100401 |
| Disease stabilization of progressive olfactory neuroblastoma (esthesioneuroblastoma) under treatment with sunitinib mesylate. | Journal of neuro-oncology 20100401 |
| Sunitinib impairs the proliferation and function of human peripheral T cell and prevents T-cell-mediated immune response in mice. | Clinical immunology (Orlando, Fla.) 20100401 |
| Reduction in skin microvascular density and changes in vessel morphology in patients treated with sunitinib. | Anti-cancer drugs 20100401 |
| Drug binding and resistance mechanism of KIT tyrosine kinase revealed by hydrogen/deuterium exchange FTICR mass spectrometry. | Protein science : a publication of the Protein Society 20100401 |
| Function of activation loop tyrosine phosphorylation in the mechanism of c-Kit auto-activation and its implication in sunitinib resistance. | Journal of biochemistry 20100401 |
| Vascular endothelial growth factor targeted therapy in the perioperative setting: implications for patient care. | The Lancet. Oncology 20100401 |
| Inhibition of receptor tyrosine kinases restores immunocompetence and improves immune-dependent chemotherapy against experimental leishmaniasis in mice. | The Journal of clinical investigation 20100401 |
| Sunitinib, sorafenib, temsirolimus or bevacizumab in the treatment of metastatic renal cell carcinoma: a review of health economic evaluations. | Journal of chemotherapy (Florence, Italy) 20100401 |
| NCCN Task Force report: update on the management of patients with gastrointestinal stromal tumors. | Journal of the National Comprehensive Cancer Network : JNCCN 20100401 |
| [Neoadjuvant treatment and breast conserving surgery - a success of clinical research in breast cancer]. | Wiener medizinische Wochenschrift (1946) 20100401 |
| Regarding: 'Costs of managing adverse events in the treatment of first-line metastatic renal cell carcinoma: bevacizumab in combination with interferon-alpha2a compared with sunitinib'. | British journal of cancer 20100330 |
| Rlip76 transports sunitinib and sorafenib and mediates drug resistance in kidney cancer. | International journal of cancer 20100315 |
| Quantification of sunitinib in mouse plasma, brain tumor and normal brain using liquid chromatography-electrospray ionization-tandem mass spectrometry and pharmacokinetic application. | Journal of pharmaceutical and biomedical analysis 20100311 |
| Bioanalytical method for the quantification of sunitinib and its n-desethyl metabolite SU12662 in human plasma by ultra performance liquid chromatography/tandem triple-quadrupole mass spectrometry. | Journal of pharmaceutical and biomedical analysis 20100311 |
| Phase II study of sunitinib in patients with metastatic urothelial cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100310 |
| Neuroendocrine tumors of the pancreas: what's new. Highlights from the '2010 ASCO Gastrointestinal Cancers Symposium'. Orlando, FL, USA. January 22-24, 2010. | JOP : Journal of the pancreas 20100305 |
| Choi response criteria for early prediction of clinical outcome in patients with metastatic renal cell cancer treated with sunitinib. | British journal of cancer 20100302 |
| Sunitinib-induced hand-foot syndrome: a new, distinct form. | Clinical and experimental dermatology 20100301 |
| A phase II study of sunitinib in patients with recurrent and/or metastatic non-nasopharyngeal head and neck cancer. | Cancer chemotherapy and pharmacology 20100301 |
| Efficacy of targeted therapy in patients with renal cell carcinoma with pre-existing or new bone metastases. | Journal of cancer research and clinical oncology 20100301 |
| A phase II study of sunitinib in Japanese patients with metastatic renal cell carcinoma: insights into the treatment, efficacy and safety. | Japanese journal of clinical oncology 20100301 |
| [Impact of immunotherapy in metastatic kidney cancer in Germany after introduction of new target therapy--results of a telephone survey of the German Society of Immuno- and Targeted Therapy (DGFIT)]. | Aktuelle Urologie 20100301 |
| [Gastrointestinal stromal tumors: evolution of a tumor concept from unclassifiable neoplasms to targeted molecular therapy]. | Der Pathologe 20100301 |
| Inhibition of tyrosine kinases by sunitinib associated with focal segmental glomerulosclerosis lesion in addition to thrombotic microangiopathy. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100301 |
| Safety and efficacy of combining sunitinib with bevacizumab + paclitaxel/carboplatin in non-small cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20100301 |
| Shrinkage of thyroid volume in sunitinib-treated patients with renal-cell carcinoma: a potential marker of irreversible thyroid dysfunction? | Thyroid : official journal of the American Thyroid Association 20100301 |
| Colony stimulating factor-1 receptor as a target for small molecule inhibitors. | Bioorganic & medicinal chemistry 20100301 |
| How does sunitinib cause hypothyroidism? | Thyroid : official journal of the American Thyroid Association 20100301 |
| Sunitinib induces hypothyroidism with a markedly reduced vascularity. | Thyroid : official journal of the American Thyroid Association 20100301 |
| Continuous Sunitinib treatment in patients with advanced hepatocellular carcinoma: a Swiss Group for Clinical Cancer Research (SAKK) and Swiss Association for the Study of the Liver (SASL) multicenter phase II trial (SAKK 77/06). | The oncologist 20100301 |
| [Recent progress in the molecular-targeting treatment of neuroendocrine tumors]. | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20100301 |
| Sunitinib for the management of advanced renal cell carcinoma. | Expert review of anticancer therapy 20100301 |
| Molecular response prediction in gastrointestinal stromal tumors. | Targeted oncology 20100301 |
| A new prognostic score derived from phase I study participants with advanced solid tumours is also valid in patients with brain metastasis. | Anticancer research 20100301 |
| [Clinical study of Sunitinib in the treatment of metastatic renal clear cell carcinoma: a single center 23 cases experience]. | Zhonghua wai ke za zhi [Chinese journal of surgery] 20100301 |
| FLT3-mutant allelic burden and clinical status are predictive of response to FLT3 inhibitors in AML. | Blood 20100218 |
| Health-related quality of life in patients with metastatic renal cell carcinoma treated with sunitinib vs interferon-alpha in a phase III trial: final results and geographical analysis. | British journal of cancer 20100216 |
| Synergistic antitumor effects of FGFR2 inhibitor with 5-fluorouracil on scirrhous gastric carcinoma. | International journal of cancer 20100215 |
| Synthesis, structure-activity relationship and crystallographic studies of 3-substituted indolin-2-one RET inhibitors. | Bioorganic & medicinal chemistry 20100215 |
| Metastatic renal cell carcinoma treated with sunitinib: early evaluation of treatment response using dynamic contrast-enhanced ultrasonography. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100215 |
| Sorafenib-associated remission of psoriasis in hypernephroma: case report. | Dermatology online journal 20100215 |
| Novel 3-arylideneindolin-2-ones as inhibitors of NAD+ -dependent histone deacetylases (sirtuins). | Journal of medicinal chemistry 20100211 |
| Sunitinib efficacy in the treatment of metastatic skin adnexal carcinomas: report of two patients with hidradenocarcinoma and trichoblastic carcinoma. | Journal of the European Academy of Dermatology and Venereology : JEADV 20100201 |
| Statins potentiate cytostatic/cytotoxic activity of sorafenib but not sunitinib against tumor cell lines in vitro. | Cancer letters 20100201 |
| Sunitinib malate for metastatic castration-resistant prostate cancer following docetaxel-based chemotherapy. | Annals of oncology : official journal of the European Society for Medical Oncology 20100201 |
| Pharmacological management of gastrointestinal stromal tumours: an update on the role of sunitinib. | Annals of oncology : official journal of the European Society for Medical Oncology 20100201 |
| A phase II study of sunitinib in patients with locally advanced or metastatic cervical carcinoma: NCIC CTG Trial IND.184. | Gynecologic oncology 20100201 |
| Successful desensitization protocol for hypersensitivity reaction caused by sunitinib in a patient with a gastrointestinal stromal tumor. | Japanese journal of clinical oncology 20100201 |
| Cytoreductive surgery in patients with metastatic gastrointestinal stromal tumor treated with sunitinib malate. | Annals of surgical oncology 20100201 |
| Combined treatment strategies in gastrointestinal stromal tumors (GISTs) after imatinib and sunitinib therapy. | Cancer treatment reviews 20100201 |
| VEGFR TKI 'resistance' or transient clinical insensitivity to VEGFR TKI in metastatic renal cell carcinoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20100201 |
| Good response to second-line bevacizumab and interferon-alpha in a sunitinib-refractory patient with metastatic renal cell carcinoma. | Anti-cancer drugs 20100201 |
| Radiation recall dermatitis triggered by multi-targeted tyrosine kinase inhibitors: sunitinib and sorafenib. | Anti-cancer drugs 20100201 |
| Re: Sequential sorafenib and sunitinib for renal cell carcinoma M. P. Sablin, S. Negrier, A. Ravaud, S. Oudard, C. Balleyguier, J. Gautier, C. Celier, J. Medioni and B. Escudier J Urol 2009; 182: 29-34. | The Journal of urology 20100201 |
| Sunitinib acts primarily on tumor endothelium rather than tumor cells to inhibit the growth of renal cell carcinoma. | Cancer research 20100201 |
| Interleukin-8 mediates resistance to antiangiogenic agent sunitinib in renal cell carcinoma. | Cancer research 20100201 |
| Bronchial fistula associated with sunitinib in a patient previously treated with radiation therapy. | The Annals of pharmacotherapy 20100201 |
| Seven 3-methylidene-1H-indol-2(3H)-ones related to the multiple-receptor tyrosine kinase inhibitor sunitinib. | Acta crystallographica. Section C, Crystal structure communications 20100201 |
| Anti-vascular endothelial growth factor therapies and cardiovascular toxicity: what are the important clinical markers to target? | The oncologist 20100201 |
| Risk of bleeding not increased by sorafenib or sunitinib. | The Lancet. Oncology 20100201 |
| Efficacy of sunitinib in advanced medullary thyroid carcinoma: intermediate results of phase II THYSU. | The oncologist 20100201 |
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| SUN vs BEVthornIFN in first-line mRCC therapy: no evidence for a statistically significant difference in progression-free survival. | British journal of cancer 20100105 |
| Metastatic adamantinoma responds to treatment with receptor tyrosine kinase inhibitor. | Acta oncologica (Stockholm, Sweden) 20100101 |
| Complete remission achieved with angiogenic therapy in metastatic renal cell carcinoma including surgical intervention. | Urologic oncology 20100101 |
| Therapeutic activity of sunitinib for Her2/neu induced mammary cancer in FVB mice. | International immunopharmacology 20100101 |
| Aortic dissection in a patient treated by sunitinib for metastatic renal cell carcinoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20100101 |
| Nephrotic syndrome caused by the angiogenesis inhibitor sorafenib. | Annals of oncology : official journal of the European Society for Medical Oncology 20100101 |
| Targeted therapies in the treatment of GIST: Adverse events and maximising the benefits of sunitinib through proactive therapy management. | Acta oncologica (Stockholm, Sweden) 20100101 |
| About tyrosine kinase inhibitors (TKIs) in prostate cancer: where do we go from here? | Annals of oncology : official journal of the European Society for Medical Oncology 20100101 |
| Phase II study of sunitinib in recurrent or metastatic squamous cell carcinoma of the head and neck: GORTEC 2006-01. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100101 |
| CT response assessment combining reduction in both size and arterial phase density correlates with time to progression in metastatic renal cancer patients treated with targeted therapies. | Cancer biology & therapy 20100101 |
| Bevacizumab, sorafenib tosylate, sunitinib and temsirolimus for renal cell carcinoma: a systematic review and economic evaluation. | Health technology assessment (Winchester, England) 20100101 |
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| Compounds in clinical Phase III and beyond. | Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20100101 |
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| Anti-cancer drugs. Editorial. | Anti-cancer drugs 20100101 |
| Renal cell carcinoma: complete pathological response in a patient with gastric metastasis of renal cell carcinoma. | Anti-cancer drugs 20100101 |
| Renal cell carcinoma: complete response. | Anti-cancer drugs 20100101 |
| Breast cancer: complete response with the combination of sunitinib and trastuzumab in a patient with grade III ductal carcinoma. | Anti-cancer drugs 20100101 |
| Colorectal cancer: response to sunitinib in a heavily pretreated colorectal cancer patient. | Anti-cancer drugs 20100101 |
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| Identification of N-(5-tert-butyl-isoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea dihydrochloride (AC220), a uniquely potent, selective, and efficacious FMS-like tyrosine kinase-3 (FLT3) inhibitor. | Journal of medicinal chemistry 20091210 |
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| Sunitinib malate in the treatment of recurrent or persistent uterine leiomyosarcoma: a Gynecologic Oncology Group phase II study. | Gynecologic oncology 20091201 |
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| N-(4-(6,7-Disubstituted-quinolin-4-yloxy)-3-fluorophenyl)-2-oxo-3-phenylimidazolidine-1-carboxamides: a novel series of dual c-Met/VEGFR2 receptor tyrosine kinase inhibitors. | Bioorganic & medicinal chemistry letters 20091201 |
| Identification of TNF-alpha and MMP-9 as potential baseline predictive serum markers of sunitinib activity in patients with renal cell carcinoma using a human cytokine array. | British journal of cancer 20091201 |
| Sunitinib paves the way for targeted therapies in neuroendocrine tumors. | Targeted oncology 20091201 |
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| Metastatic renal cell carcinoma: current standards of care. | Clinical journal of oncology nursing 20091201 |
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| Electrocardiographic characterization of the QTc interval in patients with advanced solid tumors: pharmacokinetic- pharmacodynamic evaluation of sunitinib. | Clinical cancer research : an official journal of the American Association for Cancer Research 20091115 |
| Phase II study of continuous daily sunitinib dosing in patients with previously treated advanced non-small cell lung cancer. | British journal of cancer 20091103 |
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| Cutaneous adverse effects in patients treated with the multitargeted kinase inhibitors sorafenib and sunitinib. | The British journal of dermatology 20091101 |
| Sunitinib, an orally available receptor tyrosine kinase inhibitor, induces monocytic differentiation of acute myelogenous leukemia cells that is enhanced by 1,25-dihydroxyvitamin D(3). | Leukemia 20091101 |
| [An image of vena cava thrombosis]. | Journal des maladies vasculaires 20091101 |
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| AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML). | Blood 20091001 |
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| A phase I study of sunitinib plus bevacizumab in advanced solid tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20091001 |
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| Tolerability of first-line therapy for metastatic renal cell carcinoma. | Cancer treatment reviews 20090501 |
| Sunitinib, a novel therapy for anthracycline- and cisplatin-refractory malignant pheochromocytoma. | Japanese journal of clinical oncology 20090501 |
| Recent advances in molecular targeted therapy for metastatic renal cell carcinoma. | International journal of urology : official journal of the Japanese Urological Association 20090501 |
| [Targeted therapies and their indications in solid neoplasias]. | La Revue de medecine interne 20090501 |
| [Potential role of antiangiogenic treatment in neuroblastoma]. | Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20090501 |
| Progress in the treatment of neuroendocrine tumors. | Current oncology reports 20090501 |
| Targeted therapies in metastatic renal cancer in 2009. | BJU international 20090501 |
| [Necrotizing hand-foot skin reaction induced by antiangiogenic in a patient with Thevenard neuroacropathy]. | Journal des maladies vasculaires 20090501 |
| Ligand-dependent platelet-derived growth factor receptor (PDGFR)-alpha activation sensitizes rare lung cancer and sarcoma cells to PDGFR kinase inhibitors. | Cancer research 20090501 |
| Cardiac dysfunction induced by novel targeted anticancer therapy: an emerging issue. | Current cardiology reports 20090501 |
| Reversible posterior leucoencephalopathy syndrome associated with sunitinib. | Internal medicine journal 20090501 |
| Assessment of vascular remodeling under antiangiogenic therapy using DCE-MRI and vessel size imaging. | Journal of magnetic resonance imaging : JMRI 20090501 |
| Phase II study of sunitinib in men with advanced prostate cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20090501 |
| Arterial hypertension and clinical benefit of sunitinib, sorafenib and bevacizumab in first and second-line treatment of metastatic renal cell cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20090501 |
| In vivo antitumor and antimetastatic activity of sunitinib in preclinical neuroblastoma mouse model. | Neoplasia (New York, N.Y.) 20090501 |
| Prognostic markers and new, innovative treatments in renal cell carcinoma. | Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20090501 |
| Is hypothyroidism a clinically relevant toxicity of tyrosine kinase inhibitors? | Thyroid : official journal of the American Thyroid Association 20090501 |
| Expanding the boundaries of clinical practice: building on experience with targeted therapies. | Annals of oncology : official journal of the European Society for Medical Oncology 20090501 |
| New paradigms in gastrointestinal stromal tumour management. | Annals of oncology : official journal of the European Society for Medical Oncology 20090501 |
| Tyrosine kinase inhibition in renal cell carcinoma and gastrointestinal stromal tumours: case reports. | Annals of oncology : official journal of the European Society for Medical Oncology 20090501 |
| Targeting both HIF-1 and HIF-2 in human colon cancer cells improves tumor response to sunitinib treatment. | Molecular cancer therapeutics 20090501 |
| Management of cardiac adverse events occurring with sunitinib treatment. | Anticancer research 20090501 |
| Sunitinib and PF-562,271 (FAK/Pyk2 inhibitor) effectively block growth and recovery of human hepatocellular carcinoma in a rat xenograft model. | Cancer biology & therapy 20090501 |
| Extra-abdominal subcutaneous metastasis of a gastrointestinal stromal tumor: report of a case and a review of the literature. | Journal of cutaneous pathology 20090501 |
| Angiogenesis regulated by VEGF and its receptors and its clinical application. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20090501 |
| Influence of bevacizumab, sunitinib and sorafenib as single agents or in combination on the inhibitory effects of VEGF on human dendritic cell differentiation from monocytes. | British journal of cancer 20090407 |
| Acute hepatic failure following monotherapy with sunitinib for ovarian cancer. | Cancer chemotherapy and pharmacology 20090401 |
| Treatment of metastatic renal cell cancer with sunitinib during chronic hemodialysis. | Urology 20090401 |
| A population pharmacokinetic meta-analysis of sunitinib malate (SU11248) and its primary metabolite (SU12662) in healthy volunteers and oncology patients. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090401 |
| Response to sorafenib after sunitinib-induced acute heart failure in a patient with metastatic renal cell carcinoma: case report and review of the literature. | Pharmacotherapy 20090401 |
| Hypothyroidism related to tyrosine kinase inhibitors: an emerging toxic effect of targeted therapy. | Nature reviews. Clinical oncology 20090401 |
| Treatment of gastrointestinal stromal tumours: imatinib, sunitinib -- and then? | Expert opinion on investigational drugs 20090401 |
| Fatal liver failure in a patient on acetaminophen treated with sunitinib malate and levothyroxine. | The Annals of pharmacotherapy 20090401 |
| Sunitinib prolongs survival in genetically engineered mouse models of multistep lung carcinogenesis. | Cancer prevention research (Philadelphia, Pa.) 20090401 |
| NICE celebrates 10th anniversary amid renal cancer drug controversy. | BJU international 20090401 |
| Hypofractionated radiotherapy with concomitant sunitinib - is there a radiosensitizing effect? | The Canadian journal of urology 20090401 |
| [Pharmacology profile of sunitinib malate (Sutent) Capsules) and clinical findings on this drug]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20090401 |
| Cardiovascular toxicities: clues to optimal administration of vascular endothelial growth factor signaling pathway inhibitors. | Targeted oncology 20090401 |
| Sunitinib-resistant gastrointestinal stromal tumors harbor cis-mutations in the activation loop of the KIT gene. | International journal of clinical oncology 20090401 |
| Renal toxicity of targeted therapies. | Targeted oncology 20090401 |
| From theoretical synergy to clinical supra-additive toxicity. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090320 |
| Phase I trial of bevacizumab plus escalated doses of sunitinib in patients with metastatic renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090320 |
| Effects of sunitinib on tumor hemodynamics and delivery of chemotherapy. | International journal of cancer 20090315 |
| Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis and reduces immunosuppressive cells. | Cancer research 20090315 |
| Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090315 |
| The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies. | Cancer research 20090315 |
| Sunitinib-induced hemoglobin changes are related to the dosing schedule. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090310 |
| Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. | Cancer cell 20090303 |
| Pharmacokinetics of sunitinib in an obese patient with a GIST. | Annals of oncology : official journal of the European Society for Medical Oncology 20090301 |
| Metastatic adrenocortical carcinoma treated with sunitinib: a case report. | Japanese journal of clinical oncology 20090301 |
| Osteonecrosis of the jaw under bisphosphonate and antiangiogenic therapies: cumulative toxicity profile? | Annals of oncology : official journal of the European Society for Medical Oncology 20090301 |
| N-(3-fluoro-4-(2-arylthieno[3,2-b]pyridin-7-yloxy)phenyl)-2-oxo-3-phenylimidazolidine-1-carboxamides: a novel series of dual c-Met/VEGFR2 receptor tyrosine kinase inhibitors. | Bioorganic & medicinal chemistry letters 20090301 |
| Sunitinib adverse event: oral bullous and lichenoid mucositis. | The Annals of pharmacotherapy 20090301 |
| Recommendations from the Spanish Oncology Genitourinary Group for the treatment of metastatic renal cancer. | Cancer chemotherapy and pharmacology 20090301 |
| Recent advances in the systemic treatment of metastatic papillary renal cancer. | Expert review of anticancer therapy 20090301 |
| Tyrosine kinase inhibitors in treatment of fibrous histiocytoma. | Experimental oncology 20090301 |
| Sunitinib-induced myxedema coma. | The American journal of emergency medicine 20090301 |
| Emerging data with antiangiogenic therapies in early and advanced non-small-cell lung cancer. | Clinical lung cancer 20090301 |
| Pathological activation of KIT in metastatic tumors of acral and mucosal melanomas. | International journal of cancer 20090215 |
| A population-based study evaluating the impact of sunitinib on overall survival in the treatment of patients with metastatic renal cell cancer. | Cancer 20090215 |
| NICE recommends kidney cancer drug it previously rejected on cost grounds. | BMJ (Clinical research ed.) 20090209 |
| Metastatic renal cell carcinoma with partial response to sunitinib complicated by ureteral obstruction from necrotic tumor. | Urology 20090201 |
| Editorial comment on: Metastin inhibits migration and invasion of renal cell carcinoma with overexpression of metastin receptor. | European urology 20090201 |
| Colonic pneumatosis and intestinal perforations with sunitinib treatment for renal cell carcinoma. | Investigational new drugs 20090201 |
| Sunitinib (Sutent, SU11248), a small-molecule receptor tyrosine kinase inhibitor, blocks function of the ATP-binding cassette (ABC) transporters P-glycoprotein (ABCB1) and ABCG2. | Drug metabolism and disposition: the biological fate of chemicals 20090201 |
| Vascular endothelial growth factor and angiopoietin-2 play a major role in the pathogenesis of vascular leakage in cirrhotic rats. | Gut 20090201 |
| Use of the tyrosine kinase inhibitor sunitinib in a patient with von Hippel-Lindau disease: targeting angiogenic factors in pheochromocytoma and other von Hippel-Lindau disease-related tumors. | The Journal of clinical endocrinology and metabolism 20090201 |
| Biopsy-proven acute interstitial nephritis associated with the tyrosine kinase inhibitor sunitinib: a class effect? | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090201 |
| Thrombotic microangiopathy secondary to VEGF pathway inhibition by sunitinib. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090201 |
| Response of the primary tumor to neoadjuvant sunitinib in patients with advanced renal cell carcinoma. | The Journal of urology 20090201 |
| Treatment of hemodialyzed patient with sunitinib. | Annals of oncology : official journal of the European Society for Medical Oncology 20090201 |
| Response to sunitinib malate in advanced alveolar soft part sarcoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090201 |
| 18F-FDG PET/CT imaging for an early assessment of response to sunitinib in metastatic renal carcinoma: preliminary study. | Cancer biotherapy & radiopharmaceuticals 20090201 |
| Sunitinib-induced cardiotoxicity is mediated by off-target inhibition of AMP-activated protein kinase. | Clinical and translational science 20090201 |
| Patient with malignant paraganglioma responding to the multikinase inhibitor sunitinib malate. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090120 |
| Early prediction of response to sunitinib after imatinib failure by 18F-fluorodeoxyglucose positron emission tomography in patients with gastrointestinal stromal tumor. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090120 |
| Molecular therapy for the treatment of hepatocellular carcinoma. | British journal of cancer 20090113 |
| Activity of sunitinib in patients with advanced neuroendocrine tumors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090110 |
| Metastatic sarcomatoid renal cell carcinoma treated with vascular endothelial growth factor-targeted therapy. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090110 |
| Surgical resection of residual disease in initially inoperable imatinib-resistant/intolerant gastrointestinal stromal tumor treated with sunitinib. | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20090101 |
| Sunitinib malate is active against human urothelial carcinoma and enhances the activity of cisplatin in a preclinical model. | Urologic oncology 20090101 |
| Pre-treatment global quality of health predicts progression free survival in metastatic kidney cancer patients treated with sorafenib or sunitinib. | Journal of cancer research and clinical oncology 20090101 |
| Risk of hypertension and renal dysfunction with an angiogenesis inhibitor sunitinib: systematic review and meta-analysis. | Acta oncologica (Stockholm, Sweden) 20090101 |
| Pharmacokinetics of sunitinib in hemodialysis. | Annals of oncology : official journal of the European Society for Medical Oncology 20090101 |
| Treatment with sunitinib enabled complete resection of massive lymphadenopathy not previously amenable to excision in a patient with renal cell carcinoma. | European urology 20090101 |
| Worsening of osteonecrosis of the jaw during treatment with sunitinib in a patient with metastatic renal cell carcinoma. | Bone 20090101 |
| Bone marrow multipotent mesenchymal stroma cells act as pericyte-like migratory vehicles in experimental gliomas. | Molecular therapy : the journal of the American Society of Gene Therapy 20090101 |
| Rationale and evidence for sunitinib in the treatment of malignant paraganglioma/pheochromocytoma. | The Journal of clinical endocrinology and metabolism 20090101 |
| Pre-surgical targeted molecular therapy in renal cell carcinoma. | BJU international 20090101 |
| Sequential therapy with sorafenib and sunitinib in renal cell carcinoma. | Cancer 20090101 |
| Early development of sunitinib in hepatocellular carcinoma. | Expert review of anticancer therapy 20090101 |
| Flare-up: an often unreported phenomenon nevertheless familiar to oncologists prescribing tyrosine kinase inhibitors. | Acta oncologica (Stockholm, Sweden) 20090101 |
| Cytoreductive nephrectomy in metastatic clear-cell renal cell carcinoma: perspectives in the tyrosine kinase inhibitor era. | The oncologist 20090101 |
| Metastatic renal cell cancer treatments: an indirect comparison meta-analysis. | BMC cancer 20090101 |
| [Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma]. | Aktuelle Urologie 20090101 |
| [Medical treatment of metastatic renal cell carcinoma after the approval and market entry of multitargeted tyrosine kinase inhibitors in Germany]. | Aktuelle Urologie 20090101 |
| Activity of nilotinib (AMN-107) alone in advanced gastrointestinal stromal tumors progressing on imatinib and sunitinib. Case report. | Chemotherapy 20090101 |
| Reversible myocardial dysfunction in a young woman with metastatic renal cell carcinoma treated with sunitinib. | Acta oncologica (Stockholm, Sweden) 20090101 |
| Increased numbers of small circulating endothelial cells in renal cell cancer patients treated with sunitinib. | Angiogenesis 20090101 |
| Tyrosine kinase inhibitors in advanced renal cell carcinoma: the evolving treatment paradigm. | Clinical genitourinary cancer 20090101 |
| Risk of hand-foot skin reaction with the multitargeted kinase inhibitor sunitinib in patients with renal cell and non-renal cell carcinoma: a meta-analysis. | Clinical genitourinary cancer 20090101 |
| Phase I study combining treatment with temsirolimus and sunitinib malate in patients with advanced renal cell carcinoma. | Clinical genitourinary cancer 20090101 |
| Phase I trial of sunitinib malate plus interferon-alpha for patients with metastatic renal cell carcinoma. | Clinical genitourinary cancer 20090101 |
| Compassionate use of sorafenib in patients with advanced renal cell cancer. | Clinical genitourinary cancer 20090101 |
| Carcinoma of the collecting ducts of Bellini of the kidney: adjuvant chemotherapy followed by multikinase inhibition with sunitinib. | Clinical genitourinary cancer 20090101 |
| Acalculous cholecystitis in a patient with metastatic renal cell carcinoma treated with sunitinib. | Clinical genitourinary cancer 20090101 |
| Retrospective analysis of the safety and efficacy of interleukin-2 after prior VEGF-targeted therapy in patients with advanced renal cell carcinoma. | Journal of immunotherapy (Hagerstown, Md. : 1997) 20090101 |
| Prolonged use of the tyrosine kinase inhibitor in a peritoneal dialysis patient with metastatic renal cell carcinoma: possible beneficial effects on peritoneal membrane and peritonitis rates. | International urology and nephrology 20090101 |
| Perioperative treatment of gastrointestinal stromal tumors. | Oncology (Williston Park, N.Y.) 20090101 |
| Perioperative tyrosine kinase inhibitors for GIST: standard ... or an idea that needs further investigation? | Oncology (Williston Park, N.Y.) 20090101 |
| Controversies in the surgical management of GIST in the era of imatinib. | Oncology (Williston Park, N.Y.) 20090101 |
| Sunitinib treatment for patients with clear-cell metastatic renal cell carcinoma: clinical outcomes and plasma angiogenesis markers. | BMC cancer 20090101 |
| Sunitinib treatment for patients with advanced clear-cell renal-cell carcinoma after progression on sorafenib. | Oncology 20090101 |
| Toxic dermatolysis, tissue necrosis and impaired wound healing due to sunitinib treatment leading to forefoot amputation. | Urologia internationalis 20090101 |
| Sunitinib malate, a receptor tyrosine kinase inhibitor, is effective in the treatment of restrictive heart failure due to heart metastases from renal cell carcinoma. | Cardiology 20090101 |
| The reverse side of the victory: flare up of symptoms after discontinuation of sunitinib or sorafenib in renal cell cancer patients. A report of three cases. | Acta oncologica (Stockholm, Sweden) 20090101 |
| Onset of male gynaecomastia in a patient treated with sunitinib for metastatic renal cell carcinoma. | Clinical drug investigation 20090101 |
| A case of acute haemolysis with 2 different multi target thyrosine kinase inhibitors in a patient with renal cancer. | Bulletin de la Societe des sciences medicales du Grand-Duche de Luxembourg 20090101 |
| How can second-line therapy for metastatic renal cell carcinoma help to define an overall management strategy? | Oncology 20090101 |
| Prostatic metastasis of renal cell carcinoma successfully treated with sunitinib. | Urologia internationalis 20090101 |
| Understanding the causes of multidrug resistance in cancer: a comparison of doxorubicin and sunitinib. | Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20090101 |
| Benefit-risk assessment of sunitinib in gastrointestinal stromal tumours and renal cancer. | Drug safety 20090101 |
| Development of sunitinib in hepatocellular carcinoma: rationale, early clinical experience, and correlative studies. | Cancer journal (Sudbury, Mass.) 20090101 |
| 11C-acetate PET for early prediction of sunitinib response in metastatic renal cell carcinoma. | Tumori 20090101 |
| [Treatment of extensive disease]. | Wiener medizinische Wochenschrift (1946) 20090101 |
| [Treatment with sunitinib and hypothyroidism--a case report and overview of literature]. | Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 20090101 |
| New therapeutic approaches in the management of metastatic renal cell carcinoma. | Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20090101 |
| Imbalance and gait disturbance from tyrosine kinase inhibition in hepatocellular cancer. | Journal of gastrointestinal cancer 20090101 |
| Sunitinib: a multitargeted receptor tyrosine kinase inhibitor in the era of molecular cancer therapies. | BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20090101 |
| Hand-foot syndrome (hand-foot skin reaction, palmar-plantar erythrodysesthesia): focus on sorafenib and sunitinib. | Oncology 20090101 |
| Multifocal brain metastases in clear cell renal cell carcinoma with complete response to sunitinib. | Urologia internationalis 20090101 |
| [Effect of sutent and celecoxib on the properties of endothelial cells in vitro]. | Voprosy onkologii 20090101 |
| Gastrointestinal stromal tumor: a bridge between bench and bedside. | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20090101 |
| Synergistic antitumor activity of ixabepilone (BMS-247550) plus bevacizumab in multiple in vivo tumor models. | Clinical cancer research : an official journal of the American Association for Cancer Research 20081215 |
| Cost effectiveness of sunitinib. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081210 |
| Sunitinib malate as the salvage therapy in advanced rectal carcinoid tumor. | International journal of colorectal disease 20081201 |
| Sequential use of the tyrosine kinase inhibitors sorafenib and sunitinib in metastatic renal cell carcinoma: a retrospective outcome analysis. | European urology 20081201 |
| Exploring the role of novel agents in the treatment of renal cell carcinoma. | Cancer treatment reviews 20081201 |
| Mechanisms of myocyte cytotoxicity induced by the multiple receptor tyrosine kinase inhibitor sunitinib. | Molecular pharmacology 20081201 |
| Vascular complications of selected cancer therapies. | Nature clinical practice. Cardiovascular medicine 20081201 |
| Nonclinical safety evaluation of sunitinib: a potent inhibitor of VEGF, PDGF, KIT, FLT3, and RET receptors. | Toxicologic pathology 20081201 |
| Novel approaches to gastrointestinal stromal tumors resistant to imatinib and sunitinib. | Current gastroenterology reports 20081201 |
| [Vascular and renal effects of anti-angiogenic therapy]. | Nephrologie & therapeutique 20081201 |
| Imatinib-induced interstitial lung disease and sunitinib-associated intra-tumour haemorrhage. | Hong Kong medical journal = Xianggang yi xue za zhi 20081201 |
| Cost-effectiveness analysis of sunitinib in patients with metastatic and/or unresectable gastrointestinal stroma tumours (GIST) after progression or intolerance with imatinib. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20081201 |
| Carcinoma of the collecting ducts of Bellini of the kidney: adjuvant chemotherapy followed by multikinase-inhibition with sunitinib. | European journal of medical research 20081124 |
| Prognosis, imatinib dose, and benefit of sunitinib in GIST: knowing the genotype. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081120 |
| Primary and secondary kinase genotypes correlate with the biological and clinical activity of sunitinib in imatinib-resistant gastrointestinal stromal tumor. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081120 |
| Tyrosine kinase inhibitors: can promising new therapy associated with cardiac toxicity strengthen the concept of teamwork? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081110 |
| Cardiac toxicity of sunitinib and sorafenib in patients with metastatic renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081110 |
| Sunitinib malate (SU-11248) alone or in combination with low-dose docetaxel inhibits the growth of DU-145 prostate cancer xenografts. | Cancer letters 20081108 |
| Blood glucose levels in patients with metastatic renal cell carcinoma treated with sunitinib. | British journal of cancer 20081104 |
| Hand foot skin reaction in cancer patients treated with the multikinase inhibitors sorafenib and sunitinib. | Annals of oncology : official journal of the European Society for Medical Oncology 20081101 |
| Effect of the multitargeted tyrosine kinase inhibitors imatinib, dasatinib, sunitinib, and sorafenib on mitochondrial function in isolated rat heart mitochondria and H9c2 cells. | Toxicological sciences : an official journal of the Society of Toxicology 20081101 |
| Addition of receptor tyrosine kinase inhibitor to radiation increases tumour control in an orthotopic murine model of breast cancer metastasis in bone. | European journal of cancer (Oxford, England : 1990) 20081101 |
| Acute exacerbation of hemorrhagic rectocolitis during antiangiogenic therapy with sunitinib and sorafenib. | Annals of oncology : official journal of the European Society for Medical Oncology 20081101 |
| [Molecular basis of targeted therapy in metastatic renal cancer]. | Der Pathologe 20081101 |
| Indomethacin inhibits cell growth of medullary thyroid carcinoma by reducing cell cycle progression into S phase. | Experimental biology and medicine (Maywood, N.J.) 20081101 |
| Documentation of thyroid function in clinical studies with sunitinib: why does it matter? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081101 |
| Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. | Nature chemical biology 20081101 |
| Sunitinib (SUTENT) for the treatment of metastatic renal cell carcinoma. | Expert review of anticancer therapy 20081101 |
| Systemic therapy for metastatic renal cell carcinoma. | The Urologic clinics of North America 20081101 |
| Sunitinib and periodic hair depigmentation due to temporary c-KIT inhibition. | Archives of dermatology 20081101 |
| Perforation of the colon by invading recurrent gastrointestinal stromal tumors during sunitinib treatment. | World journal of gastroenterology 20081021 |
| Quantification of sunitinib in human plasma by high-performance liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081015 |
| Sunitinib reverses type-1 immune suppression and decreases T-regulatory cells in renal cell carcinoma patients. | Clinical cancer research : an official journal of the American Association for Cancer Research 20081015 |
| Thyrotoxicosis during sunitinib treatment for renal cell carcinoma. | Clinical endocrinology 20081001 |
| Re: Pierre I. Karakiewicz, Nazareno Suardi, Claudio Jeldres, et al. Neoadjuvant Sutent induction therapy may effectively down-stage renal cell carcinoma atrial thrombi. Eur Urol 2008;53:845-8. | European urology 20081001 |
| Acute severe hypothyroidism induced by sunitinib. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20081001 |
| [Value of targeted therapies for renal cell cancer]. | Der Urologe. Ausg. A 20081001 |
| [Targeted therapy - point blank or single shot]. | Der Urologe. Ausg. A 20081001 |
| Prognostic nomogram for sunitinib in patients with metastatic renal cell carcinoma. | Cancer 20081001 |
| Novel drugs for renal cell carcinoma. | Expert opinion on investigational drugs 20081001 |
| [Systemic therapy of metastasizing renal cell carcinoma]. | Der Urologe. Ausg. A 20081001 |
| Recent advances in the treatment of renal cell carcinoma and the role of targeted therapies. | European journal of cancer (Oxford, England : 1990) 20081001 |
| Targeted therapies for metastatic renal cell carcinoma: an overview of toxicity and dosing strategies. | The oncologist 20081001 |
| Rapid improvement in pain and functional level in a patient with metastatic renal cell carcinoma: a case report and review of the literature. | Journal of palliative medicine 20081001 |
| Drug essentials. Small molecule multitargeted TKI therapy. | Oncology (Williston Park, N.Y.) 20081001 |
| Sunitinib-induced macrocytosis in patients with metastatic renal cell carcinoma. | Cancer 20080915 |
| Sunitinib-induced myeloid lineage redistribution in renal cell cancer patients: CD1c+ dendritic cell frequency predicts progression-free survival. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080915 |
| Major treatment improvements encourage kidney cancer researchers to seek further gains. | Journal of the National Cancer Institute 20080903 |
| Cytoreductive nephrectomy in the era of targeted molecular agents: is it time to consider presurgical systemic therapy? | European urology 20080901 |
| Inhibition of intra-abdominal adhesion formation with the angiogenesis inhibitor sunitinib. | The Journal of surgical research 20080901 |
| Neoadjuvant targeted therapy and advanced kidney cancer: observations and implications for a new treatment paradigm. | BJU international 20080901 |
| Cardiotoxicity associated with the cancer therapeutic agent sunitinib malate. | Annals of oncology : official journal of the European Society for Medical Oncology 20080901 |
| Sunitinib in the treatment of tubulocystic carcinoma of the kidney. A case report. | Annals of oncology : official journal of the European Society for Medical Oncology 20080901 |
| Heterogeneity of kinase inhibitor resistance mechanisms in GIST. | The Journal of pathology 20080901 |
| von Hippel-Lindau gene status and response to vascular endothelial growth factor targeted therapy for metastatic clear cell renal cell carcinoma. | The Journal of urology 20080901 |
| Targeted therapy in renal cell carcinoma. | Current opinion in urology 20080901 |
| The case / progressive hypertension and proteinuria on anti-angiogenic therapy. | Kidney international 20080901 |
| Evolving strategies for the management of hand-foot skin reaction associated with the multitargeted kinase inhibitors sorafenib and sunitinib. | The oncologist 20080901 |
| Novel therapeutic options in metastatic renal cancer - review and post ASCO 2007 update. | Reviews on recent clinical trials 20080901 |
| Continuous daily dosing of sunitinib in patients with metastatic renal cell cancer. | Onkologie 20080901 |
| Continuous therapy with sunitinib in patients with metastatic renal cell carcinoma. | Onkologie 20080901 |
| [Renal cell carcinoma]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080901 |
| Sunitinib-induced acute hemolysis without hypertension: a case report. | Clinical genitourinary cancer 20080901 |
| Phase II trial of sunitinib for the therapy of progressive metastatic castration-refractory prostate cancer after previous docetaxel chemotherapy. | Clinical genitourinary cancer 20080901 |
| Cardiovascular toxicity of new agents. | Clinical advances in hematology & oncology : H&O 20080901 |
| [Anti-angiogenic treatment in the management of metastatic renal cell carcinoma]. | Bulletin du cancer 20080901 |
| Scrotal cutaneous side effects of sunitinib. | The New England journal of medicine 20080828 |
| Economic evaluation of sunitinib malate for the first-line treatment of metastatic renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080820 |
| Secondary erythrocytosis produced by the tyrosine kinase inhibitors sunitinib and sorafenib. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080820 |
| Watchdog set to reject four drugs for kidney cancer on the NHS. | BMJ (Clinical research ed.) 20080814 |
| The clinical implications of sunitinib-induced hypothyroidism: a prospective evaluation. | British journal of cancer 20080805 |
| Sunitinib in the management of gastrointestinal stromal tumours (GISTs). | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20080801 |
| Sunitinib-related fulminant hepatic failure: case report and review of the literature. | Pharmacotherapy 20080801 |
| Antitumor activity and biomarker analysis of sunitinib in patients with bevacizumab-refractory metastatic renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080801 |
| Quality of life in patients with metastatic renal cell carcinoma treated with sunitinib or interferon alfa: results from a phase III randomized trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080801 |
| Palmar-plantar erythrodysesthesia secondary to sunitinib treatment resulting in necrotic foot syndrome aggravated by background diabetic vascular disease. | Archives of dermatology 20080801 |
| [Molecular targeted therapy for renal cell carcinoma]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20080801 |
| Predictive factors for severe toxicity of sunitinib in unselected patients with advanced renal cell cancer. | British journal of cancer 20080722 |
| Activity of sunitinib in patients with advanced neuroendocrine tumors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080710 |
| Efficacy of sunitinib and sorafenib in non-clear cell renal cell carcinoma: results from expanded access studies. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080710 |
| Initial testing (stage 1) of sunitinib by the pediatric preclinical testing program. | Pediatric blood & cancer 20080701 |
| Surgical morbidity associated with administration of targeted molecular therapies before cytoreductive nephrectomy or resection of locally recurrent renal cell carcinoma. | The Journal of urology 20080701 |
| Pyoderma gangrenosum: another cutaneous side-effect of sunitinib? | The British journal of dermatology 20080701 |
| SU11248 (sunitinib) sensitizes pancreatic cancer to the cytotoxic effects of ionizing radiation. | International journal of radiation oncology, biology, physics 20080701 |
| Biomarkers of angiogenesis for the development of antiangiogenic therapies in oncology: tools or decorations? | Nature clinical practice. Oncology 20080701 |
| Stability of sunitinib in oral suspension. | The Annals of pharmacotherapy 20080701 |
| Renal cell carcinoma: the translation of molecular biology into new treatments, new patient outcomes, and nursing implications. | Oncology nursing forum 20080701 |
| Sunitinib-associated lymphocytic thyroiditis without circulating antithyroid antibodies. | Thyroid : official journal of the American Thyroid Association 20080701 |
| [Antiangiogenics: new therapeutic standards in metastatic kidney cancer]. | Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20080701 |
| Novel approaches to imatinib- and sunitinib-resistant GIST. | Current oncology reports 20080701 |
| [Gastrointestinal stromal tumors. An update]. | Revista medica de Chile 20080701 |
| Sorafenib, but not sunitinib, affects function of dendritic cells and induction of primary immune responses. | Blood 20080615 |
| A pharmaco-economic analysis of second-line treatment with imatinib or sunitinib in patients with advanced gastrointestinal stromal tumours. | British journal of cancer 20080603 |
| Blockade of MEK/ERK signaling enhances sunitinib-induced growth inhibition and apoptosis of leukemia cells possessing activating mutations of the FLT3 gene. | Leukemia research 20080601 |
| Targeting c-KIT, PDGFR in cancer of unknown primary: a screening study for molecular markers of benefit. | Journal of cancer research and clinical oncology 20080601 |
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| Rare case of hemangiopericytoma responds to sunitinib. | Translational research : the journal of laboratory and clinical medicine 20080301 |
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| Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma and various other solid tumors. | The Journal of steroid biochemistry and molecular biology 20080201 |
| New developments in multitargeted therapy for patients with solid tumours. | Cancer treatment reviews 20080201 |
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| Supra-additive antitumor effect of sunitinib malate (SU11248, Sutent) combined with docetaxel. A new therapeutic perspective in hormone refractory prostate cancer. | Journal of cancer research and clinical oncology 20080101 |
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| Gentisyl alcohol derivatives from the marine-derived fungus Penicillium terrestre. | Journal of natural products 20080101 |
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| Brain metastases in patients with renal cell cancer receiving new targeted treatment. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080101 |
| Thymic carcinoid responds to neoadjuvant therapy with sunitinib and octreotide: a case report. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20080101 |
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| An update on the medical therapy of advanced metastatic renal cell carcinoma. | Scandinavian journal of urology and nephrology 20080101 |
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| Pathological evidence of necrosis in recurrent renal mass following treatment with sunitinib. | International journal of urology : official journal of the Japanese Urological Association 20071201 |
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| Randomized, double-blind, placebo-controlled phase II trial of maintenance sunitinib versus placebo after chemotherapy for patients with advanced urothelial carcinoma: scientific rationale and study design. | Clinical genitourinary cancer 20071201 |
| FLT3 kinase inhibitors in the management of acute myeloid leukemia. | Clinical lymphoma & myeloma 20071201 |
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| Sunitinib efficacy against advanced renal cell carcinoma. | The Journal of urology 20071101 |
| Playing only one instrument may be not enough: limitations and future of the antiangiogenic treatment of cancer. | BioEssays : news and reviews in molecular, cellular and developmental biology 20071101 |
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| Reversible cognitive disorders after sunitinib for advanced renal cell cancer in patients with preexisting arteriosclerotic leukoencephalopathy. | Annals of oncology : official journal of the European Society for Medical Oncology 20071001 |
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| Blood-based biomarkers of SU11248 activity and clinical outcome in patients with metastatic imatinib-resistant gastrointestinal stromal tumor. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070501 |
| Vascular endothelial growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer: a review of recent clinical trials. | Reviews on recent clinical trials 20070501 |
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| SU-011248, a vascular endothelial growth factor receptor-tyrosine kinase inhibitor, controls chronic psoriasis. | Translational research : the journal of laboratory and clinical medicine 20070301 |
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| Approval summary: sunitinib for the treatment of imatinib refractory or intolerant gastrointestinal stromal tumors and advanced renal cell carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070301 |
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| Role of anti-angiogenesis agents in treating NSCLC: focus on bevacizumab and VEGFR tyrosine kinase inhibitors. | Current treatment options in oncology 20070201 |
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| Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. | The New England journal of medicine 20070111 |
| Salvation by registration. | The New England journal of medicine 20070111 |
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| Sunitinib malate and sorafenib may be beneficial at the treatment of advanced bladder cancer due to their anti-angiogenic effects. | Medical hypotheses 20070101 |
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| Targeting von Hippel-Lindau pathway in renal cell carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20061215 |
| Targeted therapy for metastatic renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061210 |
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| Tyrosine kinase inhibitors compared with cytokine therapy for metastatic renal cell carcinoma: overview of recent clinical trials differentiating clinical response and adverse effects. | Clinical genitourinary cancer 20061201 |
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| FLT3 K663Q is a novel AML-associated oncogenic kinase: Determination of biochemical properties and sensitivity to Sunitinib (SU11248). | Leukemia 20061101 |
| Gastrointestinal stromal tumors: imatinib and beyond. | Current treatment options in oncology 20061101 |
| Beyond imatinib: second generation c-KIT inhibitors for the management of gastrointestinal stromal tumors. | Clinical colorectal cancer 20061101 |
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| Clinical response to therapy targeted at vascular endothelial growth factor in metastatic renal cell carcinoma: impact of patient characteristics and Von Hippel-Lindau gene status. | BJU international 20061001 |
| An orally administered multitarget tyrosine kinase inhibitor, SU11248, is a novel potent inhibitor of thyroid oncogenic RET/papillary thyroid cancer kinases. | The Journal of clinical endocrinology and metabolism 20061001 |
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